3655

Species: Tetrahymena
Alias: 3655, PreTt03655, 96.m00124, TTHERM_00655570, 6
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2

Sequence

Name Sequence Type Origin Length Description Download
3655.AA Protein None 418 None Fasta, JSON
3655.NA RNA None 1257 None Fasta, JSON
3655.kin_dom Protein Kinase Domain None 278 None Fasta, JSON

Protein domain

Protein domains of 3655.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 3655.AA AGC 22-299 24 3.2e-123 320.06 In-house 1-395 (395) Show / Hide
Range on Protein: 22-299
Range on HMM: 1-395/395
Sequence Identity: 24% (104 aa)

FYFHFVIGRGGFGKVWKVESK------KQKQLYALKEMSKSK-IISKR--SVQSVMNE------------KQLLSSLR----------HDFLIN-MIYAF
| |. |||.|.||||. |. |        ...||.| ..|.. |. |.   |. .|.|            .. |. ..          |.|... . |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

SDRSN--LYLVMDLLT---------GG-DLRFHIS---RHRRFTEQQTKFFAAC-------IVVGLEYLHQ-NGILHRD-IKPENLVFDNKGYLRITDLG
 | ..  ||.||...          || .| .|.    . .||.|....|.||.       || .|||||. .|| ||| .||||...|..|....|| |
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

IARI--------------------------------------WKPEN--------------SSDTSG--TPGYMAPEVMCRQNHGVAVDYYA--LGIIVY
 . .                                      |. .|               .   |  || |||||.     .| |.|...  ||.. |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ECMMGRRPYLGRTRQ----------EIRDQILARQVQIKKSEVP-----------DKWSLEAADFCNRVRKNLQVYQDKQKYFFQKQLIQRKPMNRLG-L
| . |. |. | ..|          |. ..|. ... |.. .             ...| || |....                   |... | .||| .
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKK-------------------LLCKDPEKRLGCG

N------GPEEVKNHPWF
.      | ||.||||||
GNDFGDKGAEEIKNHPWF

Kinase 3655.AA Ciliate-E2-Unclassified 22-299 30 5e-116 391.78 In-house 1-352 (352) Show / Hide
Range on Protein: 22-299
Range on HMM: 1-352/352
Sequence Identity: 30% (113 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLYALKEMSKSKIISKRSVQSV---------MNEKQ-------------LLSSLRHDFLINMIYAFSDRSNLYLVM
. .. .||.||||||.|.. |||||.||.|.|.|..|.........         ||.|.             .|... | |...|.|.| |. |.|.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

DLLTGGDLRFHIS----------------RH-RRFTEQQTK-----FFAACIVVGLEYLHQNG-ILHRDIKPENLVFDNKG---YLRITDLGIAR-----
... ||||...|.                .. ..|||||.|     |..|.|..||||||... |.||||||||..|||.|   |..|.|.||..     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------IWKPENSSDTSGTPGYM----APEVMCRQNHG----VAVDYYALGIIVYECMMGRRPYLGRTRQE----------------IRDQILA
            |||........|||.||    ||||...||..     ..|...||.| ||...|..|. .... .                ....|..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

RQVQIKKSE---VPDKWSLEAADFCNRVRKNLQVYQDKQKYFFQKQLIQRKPMNRLGLN-GPEEVKNHPWF
...|..|..   .|..|| ||.||.|                   .|.|... .... . ..|...|||||
KNIQFPKFPWQQIPKHWSPEAKDFIN-------------------DLLQKMLKKNPNKRITFEQILNHPWF

Kinase 3655.AA Ciliate-E2 22-299 25 1.6e-95 323.61 In-house 1-365 (365) Show / Hide
Range on Protein: 22-299
Range on HMM: 1-365/365
Sequence Identity: 25% (100 aa)

FYFHFVIGRGGFG-----KVWKVES------------------KKQKQLYALKEMSKSKIISKRSVQSVM----------NEKQLLSSLRHDFLINMIYA
. |. .||.|.||     |||||                    | ....||.| |.|..|... .....|          |||..|..| |...|.|...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FS--DRSNLYLVMDLLTGGDLRFHIS------------------RHRR-FTEQQTK-------FFAACIVVGLEYLHQNG-ILHRDIKPENLVFDNKGYL
|   |..|.||||... ||||. .|                   .... ...|...       |..|||...|||||... |.||||||||..|     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RITDLGIARI---------------WKPENSSDT-------------------SGTPGYMAPEVMCRQN---------HGVAVDYYALGIIVYECMMGRR
 |.|.|....               |... ..||                    |||||||||.  ...         .. ..|...||.| ||...|..
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYLGRTRQEIRDQILARQVQIKKSE-------------VPDKWSLEAADFCNRVRKNLQVYQDKQKYFFQKQLIQRKPMNRLGLNGPEEVKNHPWF
|.         .||.  .... . |              ..|||.|. |.... . . .            ...|..| .|..  |.|...|||||
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKK-F-G-K------------RMLQKDPEKRIT--GWEQILNHPWF

Kinase 3655.AA S_TKc 22-299 27 8e-81 275.74 SMART 1-231 (231) Show / Hide
Range on Protein: 22-299
Range on HMM: 1-231/231
Sequence Identity: 27% (79 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLYALKEMSKSKIISKRSVQSVMNEKQLLSSLRHDFLINMIYAFSDRSNLYLVMDLLTG--GDLRFHISRHRR---
. .. .||.|.||||.|.  || ....|.|...          .....| |.|.. .|.........| | ..||.||... |  |||. .| ...|   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTEQQTKFFAACIVVGLEYLHQNGILHRDIKPENLVFDNKGYLRITDLGIARIWKPENSSDTSGTPGYMAPEVMCRQNHGV-AVDYYALGIIVYECM
   |.| ...|... |. .|||.|..||.|||.||||. .|.   . |.| |.||.      .   ||| ||||||.    .|  ..| ...|.|.||..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

MGRRPYLGRTRQEIRDQILARQVQIKKSEVPDKWSLEAADFCNRVRKNLQVYQDKQKYFFQKQLIQRKPMNRLGLNGPEE----VKNHPWF
 |. |.   . |.. ..|.                                  ...   | ... |. | .|..     .    .|.||||
CGYPPFP--QMQMMFKKIG----------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 3655.AA Akt 22-299 33 2.6e-77 246.69 In-house 1-264 (264) Show / Hide
Range on Protein: 22-299
Range on HMM: 1-264/264
Sequence Identity: 33% (97 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLY-ALKEMSKSKIISKRSVQSVMNEKQLLSSLRHDFLINMIYAFSDRSNLYLVMDLLTGGDLRFHISRHRRFTEQ
|.|  |.|.| ||||  |. |. ...| |.|  .|..|| |. |. .. |. .|   .| |..|. |.| .  .||.|||   ||.| .|..| |||.|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

QTKFFAACIVVGLEYLHQNGILHRD-IKPENLVFDNKGYLRITDLGIAR-I-WKPENSSDT-SGTPGYMAPEVMCRQNHGVAVDYYA-LGIIVYECMMGR
...|..| |. ..|.||...|  ||  ||||.. |..|....|| | .. .  |     .|  ||| |.|||.   . |. ||| .. ||.. || | ||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

RPYLGRTRQEIRDQILARQVQIKKSEVPDKWSLEAADFCNRVRKNLQVYQDKQKYFFQKQLIQRKPMNRLG--LNGPEEVKNHPWF
 |.  . ...  ..|.  .|....    |..| |. |. ..                   | .. | .|||   |. .|.|.||||
PPFYNQDHHQMFKKIKNQPVKFPDK---DWISPECKDLISG-------------------LLNKDPKKRLGGGPNDAQEIKRHPWF

Kinase 3655.AA SGK 22-248 35 2.1e-73 225.9 In-house 1-255 (283) Show / Hide
Range on Protein: 22-248
Range on HMM: 1-255/283
Sequence Identity: 35% (90 aa)

FYFHFVIGRGGFGKVWKVESKKQ------------------KQLYALKEMSKSKII-------SKRSVQSVMNEK-QLLSSLRHDFLINMIYAFSDRSNL
| |  ||| |.||||  |. |.                   ...||.|  .|  ||        | ..  .| |.  .|. ..| |..|  |||     |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLVMDLLTGGDLRFHISRHRRFTEQQTKFFAACIVVGLEYLHQNGILHRDIKPENLVFDNKGYLRITDLGIAR--IWKPENSSDTSGTPGYMAPEVMCRQ
|.||| . ||.. .|. | ..| | . .| || ||  |||||   | .|| ||||.. | .|....|| | .   | . .  .   ||| |.||||.  |
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

NHGVAVDYYALGIIVYECMMGRRPYLGRTRQEIRDQILARQVQIKKSEVPDKWSL
 |. .|| . ||.. || |.|  |.  | .|.  |.|.    ||...  .| |.|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDL

Kinase 3655.AA AktR 22-299 31 2.2e-70 240.16 In-house 1-268 (268) Show / Hide
Range on Protein: 22-299
Range on HMM: 1-268/268
Sequence Identity: 31% (90 aa)

FYFHFVIGRGGFGKVWKVESK-KQKQLYALKEMSKSKIISKRSVQSVMNEKQLLS-SLRHDFLINMIYAFSDRSNLYLVMDLLTGGDLRFHISRHRRFTE
| .. ..|.|.||||  |. | . ...||.|  .|.||| ..  . . .|.. .    .| |.... |.| ....|...|.   ||.| .|... ..|.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

QQTKFFAACIVVGLEYLHQN-GILHRDIKPENLVFDNKGYLRITDLGIAR--IWKPENSSDTS--GTPGYMAPEVMCR-QNHGVAVDYYALGIIVYECMM
.|..|..| |. .||||||.  |  ||.||||.. |  |...||| | ..  . . ..   .|  ||| |||||.  . . |. .||..|.|| .|| ..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GRRPYLGRTRQEIRDQILARQ-VQIKKSEVPDKWSLEAADFCNRVRKNLQVYQDKQKYFFQKQLIQRKPMNRLG--LNGPEEVKNHPWF
|  |     .... . |.  | .......   . | .. |...|                  .| .. | .|||   ||.||.|.||||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPS---YFSSQCKDLIQR------------------KLLCKNPNKRLGYYCNGWEEIKSHPWF

Kinase 3655.AA Pkinase 22-256 29 5e-67 233.79 Pfam 1-272 (293) Show / Hide
Range on Protein: 22-256
Range on HMM: 1-272/293
Sequence Identity: 29% (82 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLYALKEMSKSKIISKRSVQSVM-NEKQLLSSLRHDFLINMIYAFSDRSNLYLVMDLLTGG----DLRFHIS--RH
. .. .||.|.||.|.|   |.  ...|.|...|... |.  .. .  .| |.. .|.|.. . ....| |....|.||... ||    ||  .||  ||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RRF--TEQQTKFFAACIVVGLEYLHQNGILHRDIKPENLVFDNKGYL----RITDLGIAR---IWKPENSSDTSGTPGYMAPEVMC-RQNHGVAVDYYAL
..|  .|.. ||..  |. ||||.|..||.|||.||||. .||.|..    .|.| |.|.   . . .  ..  |||.||||||   .| .| .|| ...
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIIVYECMMGRRPYLGR------TRQEIRDQILARQVQIKKSEVPD----------------KWSLEAADFCNR
|.|.|| . || |. |.      . ... ..|. ...    ..  .                .|| |. ||...
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

Kinase 3655.AA CAMK 27-253 18 1.6e-63 203.29 In-house 1-401 (425) Show / Hide
Range on Protein: 27-253
Range on HMM: 1-401/425
Sequence Identity: 18% (73 aa)

VIGRGGFGKVWKVESKKQK------------QLYALKEMSKSKIIS-------------------------KRSVQSVMNEKQLLSS-------LRHDFL
..|||.|||| ... |. .            | .| | ..|.|. .                          .. ..|..| .....       |.|  .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

INMIYAFSD-------------------RSNLYLVM---DLLTGG----DLRFHISRH---------------RRFTEQQTKFFAACIVVGLEYLHQNGI
|... .. |                   ....|.||   .. .||    ||  .| .|               .||||......   |. ...|.|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDIKPENLVFDNKG----------------Y-LRITDLGIARIWKPEN-------------------------SSDTSGTPGYMA-PEVMCRQN----
 |||.||||. .|...                . . |.| | |.. .| .                          ..  |||.||| |||  ..     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------HGVAVDYYALGIIVYECMMGRRPYLGRTRQEIRD---------QILARQVQIKKSEVPDKWSL-----------------------EAAD
          .| ..|  ..|.| | .  |. |. | ...||..         ... .  . | .  |...|                        |. |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

F
.
L

Kinase 3655.AA RSK 25-231 33 6.6e-62 211.99 In-house 1-228 (278) Show / Hide
Range on Protein: 25-231
Range on HMM: 1-228/278
Sequence Identity: 33% (76 aa)

HFVIGRGGFGKVWKVESK---KQKQLYALKEMSKSKIISK-RSVQSVMNEKQLLSSLR-HDFLINMIYAFSDRSNLYLVMDLLTGGDLRFHISRHRR---
. | |.||.|||  .  .   ...|.|| |  .|.||. . ...  .| | . |.  . | |...  ||| . . |||.|... ||.|  |......   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTEQQTKFFAACIVVGLEYLHQNGILHRDIKPENLVFDN---KGYLRITDLGIARIWKPENSSDTS---GTPGYMAPEVMC---RQN-HGVAVDYYALGI
|.|   .| .| ||. .|.||| || |||.|||| ..|.    | ...|| | ... ...... |    .|  |||||.     .|. |. |.|.. ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

IVYECMMGRRPYLG---RTRQEIRDQIL
. ||  .|..|. |    .|.|| ..|.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQ

Kinase 3655.AA PKA 22-217 37 2.4e-57 196.85 In-house 1-198 (263) Show / Hide
Range on Protein: 22-217
Range on HMM: 1-198/263
Sequence Identity: 37% (75 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLYALKEMSKSKIISKRSVQSVMNEKQLLSSLRHDFLIN-MIYAFSDRSNLYLVMDLLTGGDLRFHISRHRRFTEQ
| .  ..|.| ||.|  . .|. .. ||.| ..|..|.  . |. |.|||. |....| |... |.. | |...||.||..  ||..  .. . .||...
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

QTKFFAA-CIVVGLEYLHQNGILHRDIKPENLVFDNKGYLRITDLGIARIWKPENSSDTSGTPGYMAPEVMCRQ-NHGVAVDYYALGIIVYECMMGRRP
..|| ||  ||  |||||.  | .|| ||||.  |..|.. ||| | |   .  ...   ||| |.|||.  .   || .||  ||||..|| . |  |
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

Kinase 3655.AA MAST 22-169 32 1.1e-45 137.16 In-house 1-151 (337) Show / Hide
Range on Protein: 22-169
Range on HMM: 1-151/337
Sequence Identity: 32% (49 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLYALKEMSKSKIISKRSVQSVMNEKQLLSSLRHDFLINMIYAFSD--RSNLYLVMDLLTGGDLRFHISRHR-RFT
|.|  .|..|..|.|..|. || ....|.| . .. .| |  |..|. |.  |. .  .|  .| |.|    .  |..||. . |||  ....    .. 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EQQTKFFAACIVVGLEYLHQNGILHRDIKPENLVFDNKGYLRITDLGIARI
|  .|.  | .| .|||||  || |||.||.|...| .| . .|| | . .
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKV

Kinase 3655.AA MAST 180-256 36 5.6e-18 50.91 In-house 230-313 (337) Show / Hide
Range on Protein: 180-256
Range on HMM: 230-313/337
Sequence Identity: 36% (31 aa)

GTPGYMAPEVMCRQN-HGVAVDYYALGIIVYECMMGRRPYLGRTRQE-IRDQILARQVQIKKSEV-----PDKWSLEAADFCNR
||| |.||||  .|  .| .||....|||.||   |  |  | |..| | ..|. ..  |   |.      |. | || | ...
GTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKK

Kinase 3655.AA TyrKc 22-261 17 1.7e-14 11.62 SMART 1-280 (280) Show / Hide
Range on Protein: 22-261
Range on HMM: 1-280/280
Sequence Identity: 17% (52 aa)

FYFHFVIGRGGFGKVWKVESKKQKQLYALKEMSKSKIISKRSVQSVMNEKQLLSSL--RHDFLINMIYAFSDR-------SNLYLVMDLLTGGDLRFHIS
  .  ..|.| ||.|.| . |   .  | | . ...      ..  |.| .....|  .|. ..... . ..          |..|| .  .|||. .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RHRR-FTEQQTKFFAACIVVGLEYLHQNGILHRDIKPENLVFDNKGYLRITDLGIARIWKPE------NSSDTS----GTPG-----YMAPEVMCRQNHG
.||. .. ..   |.  |  | ||||.... |||.   |   ....  .|.| | .| .. .       .  ..    |. .      ||||..      
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

VAVDYYALGIIVYE-CMMGRRPYLG-----RTRQEIRDQILARQVQIKKSE--------VPDKWSLEAADFCNR----------VRKNL
 . | .. |.  .| .  |  || |      . ||.. .. ..    .  .         ||.      . ...          ... .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 3655.AA Pkinase_Tyr 22-146 23 5.5e-11 37.83 Pfam 1-137 (270) Show / Hide
Range on Protein: 22-146
Range on HMM: 1-137/270
Sequence Identity: 23% (32 aa)

FYFHFVIGRGGFGKVWKVESK----KQKQLYALKEMSKSKIISKRS--VQSVMNEKQLLSSL-RHDFLINMIYAFS-DRSN--LYLVMDLLTGGDLRFHI
  |  ..|.| ||.|.| . |    ..|.  | | . |    ...    .. |.| .....| .|. ..... . . ..    .|.|| .  .|||. . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

SRH----RRFTEQQTKFFAACIVVGLEYLHQNGILHRDI
 .|    ...| ..   ... |  |.|||..... |||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL

Kinase 3655.AA SGK 274-299 44 2.4e-09 24.51 In-house 257-283 (283) Show / Hide
Range on Protein: 274-299
Range on HMM: 257-283/283
Sequence Identity: 44% (12 aa)

KQLIQRKPMNRLGLN-GPEEVKNHPWF
..| |. | .||| . . .|.||||.|
QGLLQKDPKKRLGTKRDFMEIKNHPFF

Kinase 3655.AA MAST 274-299 53 2.6e-08 20.79 In-house 312-337 (337) Show / Hide
Range on Protein: 274-299
Range on HMM: 312-337/337
Sequence Identity: 53% (14 aa)

KQLIQRKPMNRLGLNGPEEVKNHPWF
|.| |  |  ||| || .|.|.|| |
KKLLQPNPKKRLGANGADEIKQHPFF

Kinase 3655.AA RSK 274-299 42 1.9e-07 23.65 In-house 251-278 (278) Show / Hide
Range on Protein: 274-299
Range on HMM: 251-278/278
Sequence Identity: 42% (12 aa)

KQLIQRKPMNRLG--LNGPEEVKNHPWF
... .| | .|||   .. ||.|.||||
RKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 3655.AA PKA 274-299 42 0.001621 12.81 In-house 236-263 (263) Show / Hide
Range on Protein: 274-299
Range on HMM: 236-263/263
Sequence Identity: 42% (12 aa)

KQLIQRKPMNRLG--LNGPEEVKNHPWF
|.|.|. .  |.|   || . .|||.||
KKLLQVDLTKRYGNMKNGVNDIKNHKWF

Kinase 3655.AA CAMK 291-299 55 0.003822 5.18 In-house 417-425 (425) Show / Hide
Range on Protein: 291-299
Range on HMM: 417-425/425
Sequence Identity: 55% (5 aa)

EEVKNHPWF
|...||||.
EQCLNHPWM

Kinase 3655.AA Pkinase 274-299 30 0.005221 11.72 Pfam 271-293 (293) Show / Hide
Range on Protein: 274-299
Range on HMM: 271-293/293
Sequence Identity: 30% (8 aa)

KQLIQRKPMNRLGLNGPEEVKNHPWF
| .....|  |..   .|....||||
KWCLCKDPKKRPT---AEQILQHPWF