5656

Species: Tetrahymena
Alias: 50.m00225, PreTt05656, 657, 3681.m00084, 5656, TTHERM_00442560
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2

Sequence

Name Sequence Type Origin Length Description Download
5656.AA Protein None 496 None Fasta, JSON
5656.kin_dom Protein Kinase Domain None 271 None Fasta, JSON
5656.NA RNA None 1491 None Fasta, JSON

Protein domain

Protein domains of 5656.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 5656.AA Ciliate-E2-Unclassified 162-432 27 2.4e-98 333.04 In-house 1-352 (352) Show / Hide
Range on Protein: 162-432
Range on HMM: 1-352/352
Sequence Identity: 27% (96 aa)

YRLGKKIGEGAHSVVRECSVRAQPEQSPHILPQNNNKELVVKIMKYRDTEILFQLLEEE-----------KIMN-EFRNNPNLVRKVDFLIEKQKKTAYL
|...|.||.|....|..|  . |  |  ..   . ...  .|.... | ||.....|..           |||. ...|.|.... ..| ....|.. |.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMERANGSNLTEILRQKTK-----------------LSEFESK-----LILKQVIQAVDYLHKKN-ICHRDITNNNIIYDESTR--RVKIIDFSVSKQLH
||| ..| .| ...... |                 ..|...|      ...|..|. .|||.|| |.||||. .||..|.. .  ..|||||. ||.. 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

KP---------------SQMLWTNTGSIGFM----APEIFTECNYD----KMVDMWSVGVVAHSLVTGYLPFYEKCDNQ--------------QQLIQAI
..               .||.||..|....|    |||.. ..|||    ...|.||.||... ...||.||| ....|              .||.| |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

IKGQLYLEEIGS-----HLSPECIDFLL----KCLEKDPSKRLKPSEALNHPWI
......  .        |.|||..||.     |.|.|.|.||. ....|||||.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 5656.AA Ciliate-E2 162-432 25 1.9e-88 300.14 In-house 1-365 (365) Show / Hide
Range on Protein: 162-432
Range on HMM: 1-365/365
Sequence Identity: 25% (98 aa)

YRLGKKIGEGAHSVVRECSVRAQPEQSPHILPQNNN------------KELVVKIMKYRDTEILFQLLEEE--------KIMNE-----FRNNPNLVRKV
| . ||||.|....|..|.|. ...|. ... . ..            |.  .|||| .. |...| . .         || ||     . |.||... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMY

DFLIEKQKKTAYLVMERANGSNLTEILRQK-----------TKLSEFESKLILKQVIQ---------------AVDYLHKKN-ICHRDITNNNIIYDEST
.. .||.... ||||| ..| .| ......            ...|.| | | ||..|               |. |||.|| |.||||  .||..    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

RRVKIIDFSVSKQLHKPSQ-------------------------------MLWTNTGSIGFMAPEIFTECN---------YDKMVDMWSVGVVAHSLVTG
  .|||||  ||......|                               | .|  |. |.|||||.   .         ||...|.||.||. . ...|
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

YLPFYEKCDNQQQLIQAIIKGQLYLEEI---------------GSHLSPECIDFLLK----CLEKDPSKRLK-PSEALNHPWI
..||          .| |..... . .                  ..|.||.|.. |    .|.|||.||.  ....|||||.
KPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 5656.AA CAMK 167-432 19 1.2e-77 249.63 In-house 1-425 (425) Show / Hide
Range on Protein: 167-432
Range on HMM: 1-425/425
Sequence Identity: 19% (83 aa)

KIGEGAHSVVRECSVRAQP----EQSPHILPQNNNKELVVKIMKYR----------------------------DTEILFQLLEEEKIMNEFR------N
..|.|. ..|..|  .  .    . . ||   | ...  .||.. .                            . . . ... | .||.  .      .
TLGRGSFGKVKLCIHKNTTGKERV-H-HI-YTN-GQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLD

NPNLVRKVDFLIEKQ-----------------KKTAYLVM---ERANGS----NLTEILRQKTK---------------LSEFESKLILKQVIQAVDYLH
 ||...  ..   ..                 .|  |.||   | . |      | . ......               ..| | . . .|...||.|.|
HPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCH

KKNICHRDITNNNIIYDEST----------------RRVKIIDFSVSKQLHK-----------------------PSQMLWTNTGSIGFMA-PEIFTECN
..||.|||.   || .|..                   .|||||  .... .                       . |...|  |. ..|| ||..  . 
SHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG

--------------YDKMVDMWSVGVVAHSLVTGYLPFYEKCD-----------NQQQLIQAIIKGQLY-LEEIGSH--------------------LSP
              |.. .||||.||.   ...||.|||..||           |...| . |.||. .  ..  |.                    .|.
HCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQ

ECIDFLLKCLEKDPSKRLKPSEALNHPWI
||.|.. |.|..||.||.. ...|||||.
ECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 5656.AA S_TKc 162-432 27 3.3e-73 250.45 SMART 1-231 (231) Show / Hide
Range on Protein: 162-432
Range on HMM: 1-231/231
Sequence Identity: 27% (79 aa)

YRLGKKIGEGAHSVVRECSVRAQPEQSPHILPQNNNKELVVKIMKYRDTEILFQLLEEEKIMNEFRNNPNLVRKVDFLIEKQKKTAYLVMERANG--SNL
|....|||.|| ..|. |  .              ...  .||.|        ... | .|. .  . ||.|.  |.  .   .  |.||| ..|   .|
YEILRKIGKGAFGKVYKCRHKK------------TGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDL

TEILRQKTK------LSEFESKLILKQVIQAVDYLHKKNICHRDITNNNIIYDESTRRVKIIDFSVSKQLHKPSQMLWTNTGSIGFMAPEIFTECNYDK-
 ...... .      ..| . . ...|...|..|.|...|.|||.   ||  ||   ..||.|| ...||        |  |.  .||||..    |.| 
FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKC

MVDMWSVGVVAHSLVTGYLPFYEKCDNQQQLIQAIIKGQLYLEEIGSHLSPECIDFLLKCLEKDPSKRLKPSEALN-------HPWI
 .|.||.|..   ...|| ||.    ..|.... |              |||..||. |||.|||.||.   |||.       |||.
KCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 5656.AA Pkinase 162-432 27 1.3e-67 235.76 Pfam 1-293 (293) Show / Hide
Range on Protein: 162-432
Range on HMM: 1-293/293
Sequence Identity: 27% (87 aa)

YRLGKKIGEGAHSVVRECSVRAQPEQSPHILPQNNNKELVVKIMKYRDTEILFQ--LLE--EEKIMNEFRNNPNLVRKVDFLIEKQKKTAYLVMERANGS
|..|.|||.|. ..|..|  .  ..            . .|||.|.|...  ..  ..   | .||... | || ||  |.  .  |.  |.||| ..| 
YHIGRKIGSGSFGCVYKCHHKGTGK------------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGG

----NLTEILR--QKTKL--SEFESKLILKQVIQAVDYLHKKNICHRDITNNNIIYDESTRR---VKIIDFSVSKQL-HKPSQMLWTNTGSIGFMAPEIF
     | ....  .....  || | | ...|......|.|...|.|||.   || .|.       |||.|| ..||. . ... ..| .|....||||. 
LYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVI

T-ECNYDKMVDMWSVGVVAHSLVTGYLPFY-E----KCDNQQQLIQAIIKGQLYLEEIGSHL------------------SPECIDFLLKCLEKDPSKRL
     |.. |||||.|.. . ...|..||. .    . ..|.|.|. | ...|  ..  ..                   |.||.||. .||.|||.||.
RGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP

KPSEALNHPWI
 . ..|.|||.
TAEQILQHPWF

Kinase 5656.AA CAMKL 162-432 28 2e-58 185.03 In-house 1-297 (297) Show / Hide
Range on Protein: 162-432
Range on HMM: 1-297/297
Sequence Identity: 28% (89 aa)

YRLGKKIGEGAHSVVRECSV-RAQPEQSPHILPQNNNKELVVKIMKYR----DTEILFQ-----------LLEEEKIMNEFR--NNPNLVRKVDFLIEKQ
||.|| .|.|. ..|. .   | .            ...  .||.. .    |. ..             .  | .||  ..    || ..  . .  ..
YRIGKTLGKGSFGKVKLATHIRTT------------GEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPE

K----KTAYLVMERANGSN--LTEILRQK----TKLSEFESKLILKQVIQAVDYLHKKNICHRDITNNNIIYDESTR-RVKIIDFSVSKQLHK----PSQ
.    |  ||||| . | .  | . ....     ...| | . . .|.. ||.|.|...|.||||   ||  ||. .  .|||||  | .  .    | |
HDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQ

MLWTNTGSIGFMAPEIFTE--CNYD-KMVDMWSVGVVAHSLVTGYLPFYEKCDN-----QQQLIQAIIKGQLYLEEIGSHLSPECIDFLLKCLEKDPSKR
.| |  ||  .||||||      || . ||.|| ||.   .|.||||| . ..|      . .   .|... | . | .|.| .|.|.. | |...|.||
KLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKR

LKPSEALNHPWI
 .  . .|||| 
PTIHQIMNHPWM

Kinase 5656.AA STE 162-432 22 6e-47 162.28 In-house 1-359 (359) Show / Hide
Range on Protein: 162-432
Range on HMM: 1-359/359
Sequence Identity: 22% (84 aa)

YRLGKKIGEGAHS-VVRECSV------------RAQPEQSPHILPQNNNKELVVKIMKYRDT-----------------EILFQLLEEEKIMNEFRN-NP
... .|||.||   |.. . .                         ....   .|.|....                  |.. |.|.| |||.....  |
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVEN----------NGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHP

NLVRKVDFLI-----EKQKKTAYLVMERANGSNLTEILRQK--------------TKLSEFESKLILKQVIQA-VDYLHKKNICHRDITNNNIIYDESTR
| |.  .  .     .|.. . ...||  .|  |..|...|              ....| . . |..|....  .|||...| ||||   ||       
NIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----

RVKIIDFSVSKQLHK---------------PSQ-MLWTNTGSIGFMAPEIFTE------CNYDKMVDMWSVGVVAHSLVTGYLPF---------YEKCDN
 ||..|| |..|| .                .| .  | .|.  .||||. .         ||  .|.||.| ..  ..||  |.         ... .|
-VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFN

Q-----QQLIQAIIKGQLY-LEEIGS----------------HLSPECIDFLLKCLEKDPSKRLKPSEALN--HPWI
.      ... .|..|.   |..  |                ..|||..||. |||.|||.|| ..|. |.  ||.|
YHMQQQFEQL-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 5656.AA CAMK-Unique 162-432 20 9.9e-47 152.17 In-house 1-363 (363) Show / Hide
Range on Protein: 162-432
Range on HMM: 1-363/363
Sequence Identity: 20% (76 aa)

YRLGKKIGEGAHSVVRECSVRAQPEQSPHILPQNNNKELVVKIMKY-RDT-EILFQ------------------LLEEEKIMNEFRNNPNLVRKVDF---
|.... ||.|. ..|.||            . . . |. ..|. |  ..  ... |                  | .|. |.  . . ||... .|.   
YKMHRIIGHGNFGHVYEC------------MDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIW-KMVDHPNIIKLYDWNNP

LIEKQKK--------------TAYLVMERANGSNLTEILRQ--------------------KTKLSE--FESKLILKQVIQAVDYLHKKNICHRDITNNN
. .  |.                |.|||...|  | ... .                    ....||   .. .|  .. .|| |.|...| |||.   |
IFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLEN

IIYDES---------------TRRVKIIDFSVSKQLH-KPSQ-MLWTNTGSIGFMAP--------------EIFTECNYDKMV----DMWSVGVVAHSLV
| . .|                 ..|..||  ..... . .  |. |  |.. .|||              |.  .  ||  .    | || ||..... 
IMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYML

TGYLPFYEKCDNQ------QQLIQAIIKGQL-YLEEIGSHL----SPECIDFLLKCLEKDPSKRLKPSEALNHPWI
.|..||.. |..         ....| ||.. ....   |.    |.| .||. .|.. ||..|.. .|.| |.||
CGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase 5656.AA RSK 248-432 32 7.3e-45 155.37 In-house 77-278 (278) Show / Hide
Range on Protein: 248-432
Range on HMM: 77-278/278
Sequence Identity: 32% (66 aa)

YLVMERANGSNLTEILRQKTK---LSEFESKLILKQVIQAVDYLHKKNICHRDITNNNIIYDE--STRRVKIIDFSVSKQ-LHKPSQMLWTNTGSIGFMA
||.||  .|  |.. |...     .|| | . .. ... ||..||.. | |||.   ||.||.  . ...|..||  .||   . .|.. |  ..| .||
YLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMA

PEIFT----ECNYDKMVDMWSVGVVAHSLVTGYLPFYEKCD-NQQQLIQAIIKGQ--LYLEEIGSHLSPECIDFLLKCLEKDPSKRLK-----PSEALNH
||. .    .. .|| .| || ||. . . ||..||.   | |...... | ||.  | .. . . ||.|. |.. |.|..||.|||.      .| ..|
PEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMP-NWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQH

PWI
||.
PWF

Kinase 5656.AA CAMK-Tt 277-432 37 9.7e-44 149.18 In-house 229-396 (396) Show / Hide
Range on Protein: 277-432
Range on HMM: 229-396/396
Sequence Identity: 37% (64 aa)

ILKQVIQAVDYLHKKNICHRDITNNNIIYDESTRRVKIIDFSVSKQL------HKPSQML------WTNTGSIGFMAPEIFTECN-YDKMVDMWSVGVVA
| ||...|..|.|.. .||||   |||  .|    ||| || |||         | . |       || || . | ||||| |   ||  .|||| |.. 
IFKQILDAIKYMHENYVCHRDLKPNNILCNEDGTCVKITDFNVSKFCDHYKNYKKDNLMNHQNIKMWTYTGTVAFSAPEIFNEDCCYDETIDMWSAGCIL

HSLVTGYLPFYEKCDNQQQLIQAIIKGQLYLE-EIGSHLSPECIDFLLKCLEKDPSKRLKPSEALNHPWI
  .  |. || .     . ||. |....   . .. .| | |  |   |||  .| .| || ..| ||||
YTMLCGQEPFQA--EYVHDLIKKICQADYNFPSHVWQHISEEAKDLIKKCLTINPEQRIKPDQMLQHPWI

Kinase 5656.AA ULK 194-432 25 9.9e-43 147.01 In-house 22-329 (329) Show / Hide
Range on Protein: 194-432
Range on HMM: 22-329/329
Sequence Identity: 25% (78 aa)

QNN---NKELVVKIMK---YRDTE-------ILFQLLEEEKIMNEFR-------NNPNLVRKVDFLIEKQKKTAYLVMERANGSNLTEILRQKTK-----
...   |.  ..|..     .  .       ....|  | ||| .          .|| |.  |.. ... .  |..||  || .| ... .. |     
KTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDT

-----LSEFESKLILKQVIQAVDYLHKKNICHRD-------ITNNNIIYDESTRR------VKIIDFSVSKQLHKP---SQMLWTNT------GSIGFMA
     ||| | . ..|| ...  .|||.|| |||       |.|... . .|. .      .|| ||  .|.. ..    ||. | .      |.  .||
EEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKT-DSK-KVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMA

PEIFT----ECNYD-KMVDMWSVGVVAHSLVTGYLPFYEKCDNQQQ------LIQA-------IIKGQLYLEEIG--SHLSPECIDFLLKCLEKDPSKRL
|.|.     ...|. . .|.||.|.. . ...|. |||.   |.|.      ||.        | | .|  .  |   ..||||.|.. ..|..|...| 
PQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRI

KPSEALNHPWI
   | .||||.
SWEELFNHPWF

Kinase 5656.AA MARK 244-432 37 1e-41 134.28 In-house 73-262 (262) Show / Hide
Range on Protein: 244-432
Range on HMM: 73-262/262
Sequence Identity: 37% (73 aa)

KKT-AYLVMERANGSNLTEILRQK--TKLSEFESKLILKQVIQAVDYLHKKNICHRDITNNNIIYDEST-RRVKIIDFSVSKQLHKPSQMLWTNTGSIGF
...  ||.|| | | .| . ....   .|.| | . | .|.. || |.|.|||.||||   ||  || . . .|||||  | .  .| |.| |  |.  .
EQHQIYLIMEYASGGELYDYIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICI-PPGQKLNTFCGTPPY

MAPEIFTECNYD-KMVDMWSVGVVAHSLVTGYLPFYEKCDNQQQLIQAIIKGQLYLEEIGSHLSPECIDFLLKCLEKDPSKRLKPSEALNHPWI
||||||    || . ||.|| |||   .|.||.|| ... .. .| . | .|.     | .|.|.|| ... . |  .|..| . .| ..|||.
MAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYD---IPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 5656.AA TyrKc 162-432 22 2.4e-13 -6.96 SMART 1-280 (280) Show / Hide
Range on Protein: 162-432
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

YRLGKKIGEGAHSVVRECSVRAQPEQSPHILPQNNNKELVVKIMKYRDTEILFQLLEEEKIMNEF-RNNPNLVRKVDFLIEKQK-----KTAYLVMERAN
 .||||.||||  .|...  .                .  || .|      .  ...| .|| ..  ..||.|| .   ....      .  ..||| . 
ITLGKKLGEGAFGEVYKGTWK---------------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMP

GSNLTEILRQKTK-LSEFESKLILKQVIQAVDYLHKKNICHRDITNNNIIYDESTRRVKIIDFSVSKQLHKP------SQMLWTNTGSIGF-------MA
. .| . || . . |.  .   .  |. .  .|||.||. |||.   |. ..|   .||| ||  |. ..        ...  . ... |        ||
HGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PEIFTECNYDKMVDMWSVGVVAHSLVTGYLPFYEKC----DNQQQLIQAIIKGQLYLEEIGSH--------LSPECIDFLLKCLEKDPSKRLKPSEALNH
|| . .. .    | || ||.   . |   . |.       . |..|. . .|  |  ..  .         ..|  .  ..| . ||..|   ||   |
PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG--YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--H

PWI
  .
ECF

Kinase 5656.AA Pkinase_Tyr 162-325 25 4.6e-05 17.77 Pfam 1-163 (270) Show / Hide
Range on Protein: 162-325
Range on HMM: 1-163/270
Sequence Identity: 25% (44 aa)

YRLGKKIGEGAHSVVRECSVRAQPEQSPHILPQNNNKELVVKIM--KYRDTE-ILFQLLEEEKIMNEFRNNPNLVRKVDFLIEKQKK-TAYLVMERANGS
 ..|||.||||  .|...  .         .|.|.. .  ||..  .. . . ..  ...| ||| .. ..||.|| .   .....    |.||| . . 
ITFGKKLGEGAFGEVYKGTWKG--------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG

NLTEILRQ----KTKLSEFESKLILKQVIQAVDYLHKKNICHRDITNNNIIYDESTRRVKIIDFSVSKQLHK
.| . ||.    | .|.  .   .  |. .. .||. ||. |||.   |.  .| .. ||| ||  .. ...
DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-NNVVKICDFGLARDIYN

Kinase 5656.AA MARK 162-177 37 0.00018 10.72 In-house 1-16 (262) Show / Hide
Range on Protein: 162-177
Range on HMM: 1-16/262
Sequence Identity: 37% (6 aa)

YRLGKKIGEGAHSVVR
|...| ||.|....|.
YKMLKTIGHGSYAKVK

Kinase 5656.AA RSK 164-179 27 0.064625 3.24 In-house 1-18 (278) Show / Hide
Range on Protein: 164-179
Range on HMM: 1-18/278
Sequence Identity: 27% (5 aa)

LGKK--IGEGAHSVVREC
|  .  .| |.....|.|
LKVLGQGGYGKVFLCRKC

Kinase 5656.AA ULK 162-176 33 0.286613 0.29 In-house 1-15 (329) Show / Hide
Range on Protein: 162-176
Range on HMM: 1-15/329
Sequence Identity: 33% (5 aa)

YRLGKKIGEGAHSVV
| | ...|.|.  .|
YCLNHCLGKGSFGKV