7231

Species: Tetrahymena
Alias: 669, 46.m00286, 7231, PreTt07231, 3679.m00136, TTHERM_00421070
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2

Sequence

Name Sequence Type Origin Length Description Download
7231.AA Protein None 1738 None Fasta, JSON
7231.kin_dom Protein Kinase Domain None 260 None Fasta, JSON
7231.NA RNA None 5217 None Fasta, JSON

Protein domain

Protein domains of 7231.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 7231.AA CAMK 1386-1640 23 3.4e-103 333.41 In-house 1-425 (425) Show / Hide
Range on Protein: 1386-1640
Range on HMM: 1-425/425
Sequence Identity: 23% (100 aa)

VIGKGAFAKVCLAVQLLTG------------KFVAIKLIDKSILRS-------------------------ESAKKRVLQEVQILKKLN------NHKHV
..|.|.|.|| |... .|.            . |||| |||. |..                         .. .|.|..|..|.|||.      .|...
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKLLEVFEN-------------------RKLIFIVT---EYFRGQ----DLMKMMKERNG-------------EPYTENQVRYMLTQIISGLRYIHGNMV
.||.||.|.                   .| ...|.   ||  |     ||  . .|. .               .|| ..|..  ||.|...|.| . .
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

LHRDIKLDNILVDSQ-----------------LNLKIIDFGISRIILK------------------------DQKMMEQCGTPAFLA-PEIIAN------
 |||.|..|||.|.                   |.|||||| .... .                        .||| ..||||.. | ||..        
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KGYEGFGSDLWSLGVLIYILLFGKVPFKGN-------------NLTELHRNILNGVLPLDEMR------------ETNVSQE--------AQD
       | | |. .| ||.||. ||.| |. || |              |. ||...|..|    ..                ..|.|        ..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLQKILKLKVKERINLEGIANSAWM
|..|.|.   ..|...| . |  ||
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 7231.AA CAMKL 1381-1640 31 2.7e-98 314.3 In-house 1-297 (297) Show / Hide
Range on Protein: 1381-1640
Range on HMM: 1-297/297
Sequence Identity: 31% (94 aa)

YKVLHVIGKGAFAKVCLAVQ-LLTGKFVAIKLIDKSILR-SESAKKR-----------VLQEVQILKKLN--NHKHVLKLLEVFENRKL------IFIVT
|... ..|||.|.|| ||.  ..||. |||| |||. ..  . .||.           . .|.||.|.||   |... ||.||.|...       |..|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYFRGQD--LMKMMKERNG--EPYTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQL--NLKIIDFGISRIILK-----DQKMMEQCGTPAFL
||  | .  |. . ... .  .. .|.. | . .||.|.. |.| ... |||||..|||.|..   |.|||||| | .. .     .||....||.|.. 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEIIAN--KGYEGFGSDLWSLGVLIYILLFGKVPFKGNNL-----TELHRNILNGVLPLDEM-RETNVSQEAQDLLQKILKLKVKERINLEGIANSAWM
||||..   | |.|.  | ||.||. | ...|..||.. ..     .   .  .       ..     || ...||..|.|. . ..|.... | |  ||
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM





Kinase 7231.AA S_TKc 1381-1640 30 4.5e-92 313.11 SMART 1-231 (231) Show / Hide
Range on Protein: 1381-1640
Range on HMM: 1-231/231
Sequence Identity: 30% (84 aa)

YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSESAKKRVLQEVQILKKLNNHKHVLKLLEVFENRKLIFIVTEYFRG--QDLMKMMKERNGEP
|..| .||||||.||....   ||. |||| |.          .....|.|||||  .|... ||..||.. . ...|.||  |   ||....|.|....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----YTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLNLKIIDFGISRIILKDQKMMEQCGTPAFLAPEIIANKGYEGFGSDLWSLGVLIYI
    ..| ..|... ||...| |.| . ..|||.| .|||.|.  ..||.|||..|..      . .|||| ..|||..   || .. .| ||.|...|.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLFGKVPFKGNNLTELHRNILNGVLPLDEMRETNVSQEAQDLLQKILKLKVKERINLEGIAN-------SAWM
.| |. ||   .. .. ..|.              |.|| |...|.|.   ..|.    . .         |.
MLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 7231.AA Ciliate-E2-Unclassified 1381-1640 25 8.3e-92 311.31 In-house 1-352 (352) Show / Hide
Range on Protein: 1381-1640
Range on HMM: 1-352/352
Sequence Identity: 25% (92 aa)

YKVLHVIGKGAFAKVCLAVQLLTGKF-------VAIKLIDKSILRSESAKKRVLQEVQILKKLNNHK----------------HVLKLLEVFENRKLIFI
||....||.|.|.||.....  ....       ....  .|.|....  ... ..|....|| ....                ...|....|.... |.|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VTEYFRGQDLMKMMKERNG---------------EPYTENQVR-----YMLTQIISGLRYIHGN-MVLHRDIKLDNILVDSQL---NLKIIDFGISRIIL
|.||..|.||....|.|..               .  ||.|..     ... ||..|| |.| . ...|||||..|||.|..    ..||||||||. . 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------KDQKMMEQCGTPAFL----APEIIANKGYEG---FGSDLWSLGVLIYILLFGKVPFKGNNLTE----------------LHRNI
                |.|.|  .|||| ..    |||.. ...|..   . .| |||||..| .|||. ||..|| ..                |..||
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

LNGVLPLDEMRE----TNVSQEAQDLLQ----KILKLKVKERINLEGIANSAWM
... .  ... .     ..|.||.|...    |.|| . ..||..| | |  |.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 7231.AA MARK 1381-1640 38 1e-91 300.07 In-house 1-262 (262) Show / Hide
Range on Protein: 1381-1640
Range on HMM: 1-262/262
Sequence Identity: 38% (103 aa)

YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSESAKKRVLQEVQILKKLNNHKHVLKLLEVFE--NRKL-IFIVTEYFRGQDLMKMMKERNGE
||.| .||.|..||| ||. ..||. |||| ..|  |    ..| |  |..|.||| .|... ||..|.|  ...  |... ||  |..|.  .|.. . 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKL-DHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

PYTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQL--NLKIIDFGISRIILKDQKMMEQCGTPAFLAPEIIANKGYEGFGSDLWSLGVLIYIL
. .|.  | . .||.|.. | | ... |||||..|||.|..   | |||||| |..|  .||  . ||||.. ||||.  | |.|.  | |||||. |..
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

LFGKVPFKGNN--LTELHRNILNGVLPLDEMRETNVSQEAQDLLQKILKLKVKERINLEGIANSAWM
. |..||.| .  . ||...||.|. .   .    || |...|.|..|..  .||. .| | .  ||
VCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 7231.AA AGC 1381-1640 22 1.4e-88 228.42 In-house 1-395 (395) Show / Hide
Range on Protein: 1381-1640
Range on HMM: 1-395/395
Sequence Identity: 22% (88 aa)

YKVLHVIGKGAFAKVCLAVQL------LTGKFVAIKLID---KSILRSESAKKRVLQE------------VQILKKLNN---------HKHVLK-LLEVF
...| |||||.| ||.|.          |||. |.| ..   | ... .   .... |             .||.|.|.         |  . | |   |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ENRKL--IFIVTE----YFR-----GQ-DLMKMMKER-NGEPYTENQVRYMLTQ-------IISGLRYIHG-NMVLHRD-IKLDNILVDSQLNLKIIDFG
.. .   ...| |    | .     |  .|. ....| .    .|...|... .       |...| |.|  . . ||| .|..||| |.. ..|. |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

ISRIILKD---------------------------------------------------QKMMEQCG--TPAFLAPEIIANKGYEGFGSDLWS--LGVLI
 . .. .|                                                   ..    ||  || ..||||.      |.  | ||  ||.|.
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

YILLFGKVPFKGNNLT----------ELHRNILNGVLPLDEM------------RETNVSQEAQDLLQKILKLKVKERIN----------LEGIANSAWM
| .|.|. || |.|            |.. .|.|| . . .              . ..|.||.||..| |.   ..|.            | | |  | 
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF





Kinase 7231.AA Ciliate-E2a 1381-1640 33 1.5e-88 260.81 In-house 1-275 (275) Show / Hide
Range on Protein: 1381-1640
Range on HMM: 1-275/275
Sequence Identity: 33% (92 aa)

YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSESAKKRVLQEVQILKKLNNHKHVLKLLEVFENRKLIFIVTEYFRGQDLMKMMKERNGEPYT
||.. .||||.|..| || .. |||  |.| ..| .  ..  |. . .|..|...| .|....|| ||.|. . ...|.||. | .|.. .|.   . . 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQL-DHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

ENQVRYMLTQIIS-GLRYIHGNMVLHRDIKLDNILVD---SQ----LNLKIIDFGISRIILKDQK--MMEQCGTPAFLAPEIIANKG------YEGFGSD
..... .. |... || |.| . ..|||.|..||| .   ..    ...|||||| .. | ||.|  |  .|||| ..|||...||       | .   |
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQY-DTKCD

LWSLGVLIYILLFGKVPFKGNNLTELHRNILNGVLPLDEMR-ETNVSQEAQDLLQKILKLKVKERINLEGIANSAWM
.||.|| .||||.|| |||| . .|   .. .  . ..      ..|.|..||..| |.   |.||. . . |. |.
MWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF

Kinase 7231.AA Ciliate-E2 1381-1640 24 5.7e-86 291.92 In-house 1-365 (365) Show / Hide
Range on Protein: 1381-1640
Range on HMM: 1-365/365
Sequence Identity: 24% (92 aa)

YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSE-------------------SAKKRVLQEVQILKKLN---------------NHKHVLKLL
||.. .||.|.|..|... . ...| .|||.||  .. .                    . .. ..|| .|....|               ||....|. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

EVFE--NRKLIFIVTEYFRGQDLMKMMKER----------NGEPYTENQVRYMLTQIIS---------------GLRYIHGNM-VLHRDIKLDNILVDSQ
|.|.  ... |..|.||. |.||.. .|..            ...||....|. .||..               .|.|.| .  ..|||||..|||.   
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---

LNLKIIDFGISRIILKD---------QKMMEQ-----------------------CGTPAFLAPEIIANKGYEG--------FGSDLWSLGVLIYILLFG
  .||||||.|... .|         .|.. .                       |||| ..||||. .|.|..        . .|.|||||..|..|||
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

KVPFKGNNLTELHRNILNGVLPLDEMRET--------------NVSQEAQDLLQK----ILKLKVKERIN-LEGIANSAWM
| ||         ..|... . ...   .              ..|||..||..|    .|. . ..||.  | | |  |.
KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 7231.AA Pkinase 1381-1640 28 1.2e-81 282.36 Pfam 1-293 (293) Show / Hide
Range on Protein: 1381-1640
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSESAKKRVLQ--EVQILKKLNNHKHVLKLLEVFENRKLIFIVTEYFRGQ----DLMKMMKER
|... .||.|.|..|....   ||| ||.| |.|.  .... ... .   |.||.|.| ||.....|...||... | .|.|| .|     ||. ... .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

NGEPY--TENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLNL----KIIDFGISRI--ILKDQKMMEQCGTPAFLAPEIIANKGYEGFGSDLW
.. ..  .|.... ...||..|| |.| . ..|||.|..|||.|.. ..    ||.|||...   . ... |.  |||| ..|||.|    | |  .| |
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGVLIYILLFGKVPFKGN------NLTELHRNILNGVLPLDEMRETNVS-----------------QEAQDLLQKILKLKVKERINLEGIANSAWM
|.|...|..|.|. ||.|       .  .....|. . |. |.  . ..|                 .|..|.. ..|... |.|.. | | .. |.
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 7231.AA ULK 1381-1640 27 6.1e-69 235.34 In-house 1-324 (324) Show / Hide
Range on Protein: 1381-1640
Range on HMM: 1-324/324
Sequence Identity: 27% (90 aa)

YKVLHVIGKGAFA-KVCLA--VQLLT-GKFVAIKLIDKSILRS-------ESAKKRVLQEVQILKKLN--NHKH--VLKLLEVFENR--KLIFIVTEYFR
| . |..|||.|. ||. .  ..  | ...||.| |||. ..        . ...   .|.||.|||.  .|..  . ||...||.   . |.|..||  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GQDLMKMMKERNGEP-------YTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLN------------LKIIDFGISRIILKD----QKMME
| || . .|.....|        .|....  . ||..|....| . . |||||..|||.                 ||| ||| .... ..    |....
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

QC------GTPAFLAPEIIA----NKGYEGFGSDLWSLGVLIYILLFGKVPFKGN--NLT----ELHRN-------ILNGVLPLDEM-RETNVSQEAQDL
..      ||| . ||.|.     .| |  . .|.||||...| .|.||.||...  ..     .| .|       | |  .. .    . ..|.| .||
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

LQKILKLKVKERINLEGIANSAWM
... |. . |.||. | | |  |.
IRRMLQYDEKDRISWEEIFNHPWF

Kinase 7231.AA ULK 1381-1640 27 6.3e-68 231.97 In-house 1-329 (329) Show / Hide
Range on Protein: 1381-1640
Range on HMM: 1-329/329
Sequence Identity: 27% (90 aa)

YKVLHVIGKGAFAKVCLAVQLLT----GKFVAIKLIDKSILRSES-------AKKRVLQEVQILKKLN---NHKH----VLKLLEVFENR--KLIFIVTE
| . |..|||.|.||. .    |    .. ||.| |||. .. ..       ... . .|..|.|||.   .||.    . ||...||.   . |.|..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YFRGQDLMKMMKERNGEP--------YTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLN------------LKIIDFGISRIILKD----Q
|  | ||.. .|.....|         .|....  . ||..|....| . . |||||..|||..                ||| ||| .. . .|    |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

KMMEQC------GTPAFLAPEIIA----NKGYEGFGSDLWSLGVLIYILLFGKVPFKGNNLTELH-----RN----------ILNGVLPLDEM-RETNVS
 || .       ||| . ||.|.     .| |  . .|.||||...| .|.||.||...  ...      ..          | .  |  .    . ..|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

QEAQDLLQKILKLKVKERINLEGIANSAWM
.| .||... |. . |.||. | . |  |.
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 7231.AA QIK 1381-1640 35 2.7e-66 226.58 In-house 1-272 (272) Show / Hide
Range on Protein: 1381-1640
Range on HMM: 1-272/272
Sequence Identity: 35% (99 aa)

YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSESAKKRVLQEVQILKKLNNHKHVLKLLEVFENRKLIFIVTEYFRGQDLMKMMKE--R----
| .   |||| || | ||    | . |||| |||| | .|  .| .  ||||.| | .| |. ||..| |  . ..|||||  . ..   . .  |    
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQK-CYREVQIMKML-YHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVK

------------NGEPYTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLNLKIIDFGISRIILKDQKMMEQCGTPAFLAPEIIANKGYEGFG
             | | .||. | . .||.|.  | |   . |||.|  ||| |...| ||.||| |    ..| .|  ||.|.. |||.   | |.|  
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK

SDLWSLGVLIYILLFGKVPFKGNNLTELHRNILNGVLPLDEMRETNVSQEAQDLLQKILKLKVKERINLEGIANSAWM
.| ||.||. |.|  |. || | .|..| . .| |   .       .||. ..|  . | .  . |.. . | .  ||
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFF----MSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase 7231.AA Pkinase_Tyr 1381-1597 27 3.2e-22 75.87 Pfam 1-232 (270) Show / Hide
Range on Protein: 1381-1597
Range on HMM: 1-232/270
Sequence Identity: 27% (65 aa)

YKVLHVIGKGAFAKVCLAVQL----LTGKFVAIKLIDKSILRSES-AKKRVLQEVQILKKLNNHKHVLKLLEVFE-NRKL--IFIVTEYFRGQDLMKMMK
 . ....|.||| .|....       |.  ||.| . |    .|   ..  ..|..|.|.| .|.....|. |    ..   |.||.||  . || .  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

ER--NGEPYTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLNLKIIDFGISRII-LKDQK--MMEQCGTPAF-LAPEIIANKGYEGFGSDLW
..  ...| |  .   | .|| .|. | . .   |||.   |.||....  || ||| .| |  .|.   . . .  | . .||| |... .    || |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKF-TTKSDVW

SLGVLIY-ILLFGKVP-FKGNNLTELHRNI-LNG
| |||.. |. .|. | ..|   .|. . |  .|
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG

Kinase 7231.AA TyrKc 1381-1638 21 5.6e-17 51.82 SMART 1-280 (280) Show / Hide
Range on Protein: 1381-1638
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

YKVLHVIGKGAFAKVCLAVQLLTGKFVAIKLIDKSILRSESAKKRVLQEVQILKKL-NNHKHVLKLLEVFENR-------KLIFIVTEYFRGQDLMKMMK
 . ....| ||| .|....       ||.| . ..       ..  ..| .|..||  .|.....|. |           . ..||.||  . || .  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ERNGEPYTENQVRYMLTQIISGLRYIHGNMVLHRDIKLDNILVDSQLNLKIIDFGISRIILKD--------QKMMEQ--CGTP----AFLAPEIIANKGY
.. ..  .  .  .. .|| .| .|.| . . |||.   |.||....  || ||| || |  |         ... .  .|        .||| | |.| 
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGK

EGFGSDLWSLGVLIY-ILLFGKVPFKG-----NNLTELHRNILNG-VLPLDEMRETN-----VSQEAQDLLQKILKLKVKERINLEGIANSA
  . || || ||... |. .|. |  |      . .|..... .|  .|  .  .        ..|  .. ..  . . ..| . . |    
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

UBA_CAMKL 7231.AA UBA_CAMKL 1683-1720 31 3e-06 20.87 In-house 1-41 (41) Show / Hide
Range on Protein: 1683-1720
Range on HMM: 1-41/41
Sequence Identity: 31% (13 aa)

DEKIIGQIEGF--GYSREYILRCLNKGGL-SHVNAIYKLIK
||.|| . .    |..|| | ..|...    |. |.| |. 
DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL