Gene 7413 (Tetrahymena)
7413
Sequence
Protein domains of 7413.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 7413.AA | Ciliate-E2-Unclassified | 24-308 | 28 | 1.7e-104 | 353.43 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 24-308
Range on HMM: 1-352/352
Sequence Identity: 28% (107 aa)
FNFLYVIGRGGFGKVWKVEHKKTKQLYAMKEMSKAKQNY-LLSNQ-----------NNK------------------MATIFIVNMVWAFQDRENLYLVM
......||.||||||.|..|||.||.||||.|.|.... .. .. ||| . .|||.|...|||..|.|.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM
DLLGGGDLRYHIGRQKK-----------------FTEEQTK-----FFIACLVQALEYLHYNS-ILHRDVKPENLVLDDQG---YLRLTDLGVAR-----
... ||||...| .|| |||.|.| |..|...|.|||||.. |.||| ||||...|..| |....|.| ..
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN
------------IWKPDNQSDTSGTPGYM----APEVMCRQVHGQSLFKNQLSFYIIQFQKSVAADYYAVGVITYECMLGKRPYIGRTRKE---------
|||........|||.|| ||||...| ...| . ..|....||| ||.. |..|. ......
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA--------------YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI
-------LRDQIIARQVQVRKSE---IPHGWSLEAADFINKVNKLEKDNINSKKYQKTIQRKPQNRLGLN-GPDEVKEHPWL
|...|.....|..|.. ||..|| ||.|||| . .|........ . .......|||.
NNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIN----------------DLLQKMLKKNPNKRITFEQILNHPWF
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| Kinase | 7413.AA | AGC | 24-308 | 22 | 1.2e-98 | 255.05 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 24-308 Range on HMM: 1-395/395 Sequence Identity: 22% (99 aa) FNFLYVIGRGGFGKVWKVEHK------KTKQLYAMKEMSKAK---------QNYLLSNQ-----------NNKMATIF-------------IVN-MVWAF |.|| |||.|.||||. |..| |...|||| ..|.. . . .. . | .... ||. . .| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QDREN--LYLVMDLLG---------GG-DLRYHI-G--RQKKFTEEQTKFFIAC-------LVQALEYLHY-NSILHRD-VKPENLVLDDQGYLRLTDLG || .. ||.||... || .| .|. | ....|.||...|..|. .| |||||| . | ||| .||||..||..|...||| | QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG VARI--------------------------------------WKPDN--------------QSDTSG--TPGYMAPEVMCRQVHGQSLFKNQLSFYIIQF . . |. .| . | || |||||. LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL--------------------- QKSVAADYYA--VGVITYECMLGKRPYIGRT----------RKELRDQIIARQ-VQVRKSEIP----------HGWSLEAADFINKVNKLEKDNINSKKY . |.|... .|.. || . |. |. | . ..|. ..|. .. .. | ..| .| || |.|.| -YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKK-------------- QKTIQRKPQNRLG-LN------GPDEVKEHPWL ... | .||| .. | .|.|.||| --LLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | 7413.AA | Ciliate-E2 | 24-308 | 22 | 1.6e-78 | 267.15 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 24-308 Range on HMM: 1-365/365 Sequence Identity: 22% (91 aa) FNFLYVIGRGGFGKVWKVEHKKTK-----------------------QLYAMKEMSKAKQNYLLS--NQNNKMA----------------TIFIVNMVWA ..|. .||.|.||.|.|....|.. ..|||| |.| . ..... ...... .|..|... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ--DRENLYLVMDLLGGGDLRYHIG------------------RQKK-FTEEQTK-------FFIACLVQALEYLHYNS-ILHRDVKPENLVLDDQGYL || |..|.||||... ||||...| .. | ....... |.|||...|||||| . |.||| ||||... . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I RLTDLGVARI---------------WKPDNQSDTSGTPGYM--------------APEVMCRQVHGQSLFKNQLSFYIIQFQKSVAADYYAVGVITYECM ..|.| ... |... ..|||.||||| |. |...... || . | . . ..|....||| ||.. KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ----QKQKGYDYKCDIWSLGVILYEML LGKRPYIGRTRKELRDQIIARQVQVRKSE-------------IPHGWSLEAADFINKVNKLEKDNINSKKYQKTIQRKPQNRLGLNGPDEVKEHPWL ||.|. .||. ... .. | ... ||.|. |.|.| .| . .|..|..|.. |......|||. FGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGK------------RMLQKDPEKRIT--GWEQILNHPWF |
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| Kinase | 7413.AA | S_TKc | 24-308 | 27 | 6e-61 | 209.71 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 24-308 Range on HMM: 1-231/231 Sequence Identity: 27% (83 aa) FNFLYVIGRGGFGKVWKVEHKKTKQLYAMKEMSKAKQNY----LLSNQNNKMATIFIVNMVWAFQDRENLYLVMDLLGG--GDLRYHIGRQKK------F . .| .||.|.||||.|. ||||....|.|... .. . .|.. .||.. .||| ..||.||....| |||. .| .... | YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF TEEQTKFFIACLVQALEYLHYNSILHRDVKPENLVLDDQGYLRLTDLGVARIWKPDNQSDTSGTPGYMAPEVMCRQVHGQSLFKNQLSFYIIQFQKSV-A .| ...|... ...||||.| . |.|||.||||. ||. . ..| |.||. . ||| ||||||. . . . PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---------------------GYGKCK ADYYAVGVITYECMLGKRPYIGRTRKELRDQIIARQVQVRKSEIPHGWSLEAADFINKVNKLEKDNINSKKYQKTIQRKPQNRLGLNGPDE----VKEHP .| ...|.| ||.. |. |. . ... ..| | || |||.| |. |..|.. . .| || CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKC----------------LQKDPEKRPTA-EALQDEWDIKCHP WL |. WF |
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| Kinase | 7413.AA | Pkinase | 24-268 | 24 | 6.3e-50 | 176.99 | Pfam | 1-272 (293) | Show / Hide |
Range on Protein: 24-268 Range on HMM: 1-272/293 Sequence Identity: 24% (71 aa) FNFLYVIGRGGFGKVWKVEHKKTKQLYAMKEMSKAKQNYLLSNQNNK------MATI---FIVNMVWAFQDRENLYLVMDLLGGG----DLRYHIG--RQ . .. .||.|.||.|.| ||.| ...|.|...| ... .. . |. . .|| . .|.|. ..|.||....|| || .| |. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH KKF--TEEQTKFFIACLVQALEYLHYNSILHRDVKPENLVLDDQGYL----RLTDLGVAR---IWKPDNQSDTSGTPGYMAPEVMCRQVHGQSLFKNQLS ..| .|.. ||.. ....|||.| ..|.|||.||||. .|..|.. ...| |.|. . . .. |||.|||||| GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV---------------- FYII-QFQKSVAADYYAVGVITYECMLGKRPYIGR--TRKELRDQIIARQVQVRKSEIPHGWS---------------------LEAADFINK | . . ..| ...|.| || ..|. |. |. . . .... . ... .. . . |. |. |||.. --IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW |
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| Kinase | 7413.AA | CAMK | 29-268 | 18 | 2.9e-48 | 153.19 | In-house | 1-404 (425) | Show / Hide |
Range on Protein: 29-268 Range on HMM: 1-404/425 Sequence Identity: 18% (75 aa) VIGRGGFGKVWKVEHKKTK------------QLYAMKEMSK------------------------------AKQNYLLSNQNNKMAT----------IFI ..|||.|||| ...||.|. | .|.| ..| .| . . . | . | TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI VNMVWAFQD-------------------RENLYLVM---DLLGGG----DLRYHIGRQ---------------KKFTEEQTKFFIACLVQALEYLHYNSI ... ...| ....|.|| .. || || .| .. ..|||....... ...|..|.| . | IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI LHRDVKPENLVLDDQG----------------Y-LRLTDLGVARIWKPDN-------------------------QSDTSGTPGYMA-PEVMCRQVHGQS ||| ||||. ||| . . . ..| | |.. .|.. .. |||.||| ||| .. |... VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM LFKNQLSFYIIQFQKSVAADYYAVGVITYECMLGKRPYIGR-------------TRKELRDQIIARQVQVRKSE--------IPHGWS-----------L | . . . ..| ..|||.| . |. |. | . .|| .|.. . . .. | |. Q--N-A-TDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQ EAADFINK |. |.|.| ECKDLIRK |
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| Kinase | 7413.AA | SGK | 75-190 | 47 | 6.5e-43 | 130.05 | In-house | 86-203 (283) | Show / Hide |
Range on Protein: 75-190 Range on HMM: 86-203/283 Sequence Identity: 47% (56 aa) FIVNMVWAFQDRENLYLVMDLLGGGDLRYHIGRQKKFTEEQTKFFIACLVQALEYLHYNSILHRDVKPENLVLDDQGYLRLTDLGVAR--IWKPDNQSDT |||| ||| . ||.||| . ||.. ||. | |.| | . .| | .| |||||| | .|| ||||..||.||...||| | . | . | . FIVNLHYAFQTKWKLYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTF SGTPGYMAPEVMCRQVHG ||| |.||||. | |. CGTPEYLAPEVLRKQPHD |
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| Kinase | 7413.AA | Akt | 75-183 | 41 | 8e-42 | 131.43 | In-house | 61-173 (264) | Show / Hide |
Range on Protein: 75-183 Range on HMM: 61-173/264 Sequence Identity: 41% (47 aa) FIVNMVWAFQDRENLYLVMDLLGGGDLRYHIGRQKKFTEEQTKFFIACLVQALEYLHYNSILHRD-VKPENLVLDDQGYLRLTDLGVAR-I-WKPDNQSD ||||.. .||. ..||.||| .||.| ||. |...|.|....|..| .. |.|.|| ..| || ||||...| .|...||| | .. . | . . FIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTK T-SGTPGYMAPEV | ||| |.|||. TFCGTPEYLAPEI |
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| Kinase | 7413.AA | YANK | 75-183 | 44 | 7.6e-38 | 126.85 | In-house | 60-169 (261) | Show / Hide |
Range on Protein: 75-183 Range on HMM: 60-169/261 Sequence Identity: 44% (49 aa) FIVNMVWAFQDRENLYLVMDLLGGGDLRYHIGRQKKFTEEQTKFFIACLVQALEYLHYNSILHRDVKPENLVLDDQGYLRLTDLGVARIWKPDNQSDT-S |.|| . ||| | .. | ||| ||||||| . .|.|. | .| .. |||||. . | |||.||.| ||..| .||. .| . | . . . | FLVNLWYSFQDEEDMFMVCDLLLGGDLRYHLQQNVHFSEDTVKLYICEMCMALEYLQEMHIIHRDIKPDNILLDEHGHVHITDFNIATMLKDNQRATSMS GTPGYMAPEV || |||||. GTKPYMAPEI |
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| Kinase | 7413.AA | RSK | 75-192 | 37 | 1.4e-34 | 121.16 | In-house | 62-192 (278) | Show / Hide |
Range on Protein: 75-192 Range on HMM: 62-192/278 Sequence Identity: 37% (49 aa) FIVNMVWAFQDRENLYLVMDLLGGGDLRYHIGRQKK---FTEEQTKFFIACLVQALEYLHYNSILHRDVKPENLVLDD---QGYLRLTDLGVARIWKPDN |||. |||. . |||.|... ||.| .|. ..| |.|. .| .| .| |.|.|| | ||| |||| ..|| .| ..||| | ... ..|. FIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDH QSDTS---GTPGYMAPEVMC---RQV-HGQS . | .| |||||. .|. |... NQWTMTFCYTIEYMAPEMLKRANQQGGHDKA |
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| Kinase | 7413.AA | AktR | 75-190 | 40 | 3.4e-32 | 113.26 | In-house | 62-183 (268) | Show / Hide |
Range on Protein: 75-190 Range on HMM: 62-183/268 Sequence Identity: 40% (49 aa) FIVNMVWAFQDRENLYLVMDLLGGGDLRYHIGRQKKFTEEQTKFFIACLVQALEYLHYN-SILHRDVKPENLVLDDQGYLRLTDLGVAR--IWKPDNQSD |||... .||..|.|...|. ||.| .|. ..|||.|||..|..| . ||||||.. | || ||||..|| |....|| | .. . . ... FIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKA TS--GTPGYMAPEVMCR-QVHG .| ||| |||||. . . |. YSFCGTPEYMAPEMITKKKGHN |
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| Kinase | 7413.AA | RSK | 75-192 | 41 | 1e-30 | 106.91 | In-house | 62-185 (271) | Show / Hide |
Range on Protein: 75-192 Range on HMM: 62-185/271 Sequence Identity: 41% (51 aa) FIVNMVWAFQDRENLYLVMDLLGGGDLRYHIGRQKKFTEEQTKFFIACLVQALEYLHYNSILHRDVKPENLVLDDQ----GYLRLTDLGVARIWKPDNQS ||| .||| ...|..||.. |||| .. .|| |.|. || | . |.|||| | ||| |||| ..||. | ....|.| | . .| FIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFSEREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGM DTS--GTPGYMAPEVMCRQVHGQS . .| |||||| || |.|. LMTFCYTANYMAPEVLKRQGHDQA |
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| Kinase | 7413.AA | SGK | 24-53 | 37 | 7.2e-13 | 35.61 | In-house | 1-48 (283) | Show / Hide |
Range on Protein: 24-53 Range on HMM: 1-48/283 Sequence Identity: 37% (18 aa) FNFLYVIGRGGFGKVWKVEHKKT------------------KQLYAMK | || ||| |.|||| |.||.. ...|||| FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMK |
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| Kinase | 7413.AA | Akt | 24-53 | 54 | 1.5e-12 | 36.31 | In-house | 1-31 (264) | Show / Hide |
Range on Protein: 24-53 Range on HMM: 1-31/264 Sequence Identity: 54% (17 aa) FNFLYVIGRGGFGKVWKVEHKKTKQLY-AMK |.||.|.|.| |||| |. |.|...| ||| FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMK |
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| Kinase | 7413.AA | Akt | 208-308 | 23 | 9.1e-11 | 30.57 | In-house | 180-264 (264) | Show / Hide |
Range on Protein: 208-308 Range on HMM: 180-264/264 Sequence Identity: 23% (25 aa) SVAADYYA-VGVITYECMLGKRPYIGRTRKELRDQIIARQVQVRKSEIP--HGWSLEAADFINKVNKLEKDNINSKKYQKTIQRKPQNRLG--LNGPDEV . |.| .. .|...|| | | |. . .... ..| .|. .| . .| |. |.|.. .. | .||| |. .|. TKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVK-----FPDKDWISPECKDLISG----------------LLNKDPKKRLGGGPNDAQEI KEHPWL |.|||. KRHPWF |
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| Kinase | 7413.AA | YANK | 24-59 | 52 | 2.4e-10 | 31.62 | In-house | 1-36 (261) | Show / Hide |
Range on Protein: 24-59 Range on HMM: 1-36/261 Sequence Identity: 52% (19 aa) FNFLYVIGRGGFGKVWKVEHKKTKQLYAMKEMSKAK | | ||.| |||| | ..|| .|||| |.| | FQILRAIGKGSFGKVCIVQKRDTKKMYAMKYMNKQK |
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| Kinase | 7413.AA | TyrKc | 24-272 | 16 | 1.6e-09 | -68.74 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 24-272 Range on HMM: 1-280/280 Sequence Identity: 16% (50 aa) FNFLYVIGRGGFGKVWKVEHKKTKQLYAMKEMSKAKQNYLLSNQNNKMATI-----FIVNMVWAFQDR-------ENLYLVMDLLGGGDLRYHIGRQKK- .. ..|.| ||.|.| . | . | | . . . . . . | . ||... . . | |..|| . .|||. .. . .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK FTEEQTKFFIACLVQALEYLHYNSILHRDVKPENLVLDDQGYLRLTDLGVARIWKPD------NQSDTS----GTPG-----YMAPEVMCRQVHGQSLFK .. .. | . |||| . . ||| | ..... . .| | .| .. | . .. |. . ||||.. LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----------- NQLSFYIIQFQKSVAADYYAVGVITYE-CMLGKRPYIG-----RTRKELRDQIIARQVQVRKSE--------IPHG--------WSLEAAD---FINKVN . . . . . | .. || .| . .|. || | . .|.. .. .. . . | | ...| | . . -NYGKF------TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHE KL .. CF |
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| Kinase | 7413.AA | RSK | 24-59 | 38 | 2.5e-09 | 29.7 | In-house | 1-39 (271) | Show / Hide |
Range on Protein: 24-59 Range on HMM: 1-39/271 Sequence Identity: 38% (15 aa) FNFLYVIGRGGFG---KVWKVEHKKTKQLYAMKEMSKAK .... .||.| |. . |..|| |.|.|||| ||. YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKAT |
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| Kinase | 7413.AA | AktR | 24-53 | 41 | 5.6e-09 | 31.06 | In-house | 1-31 (268) | Show / Hide |
Range on Protein: 24-53 Range on HMM: 1-31/268 Sequence Identity: 41% (13 aa) FNFLYVIGRGGFGKVWKVEHK-KTKQLYAMK | .. ..|.|.|||| |..| .....|||| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMK |
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| Kinase | 7413.AA | SGK | 212-308 | 29 | 5.2e-07 | 17.18 | In-house | 207-283 (283) | Show / Hide |
Range on Protein: 212-308 Range on HMM: 207-283/283 Sequence Identity: 29% (29 aa) DYYAVGVITYECMLGKRPYIGRTRKELRDQIIARQVQVRKSEIPHGWSLEAADFINKVNKLEKDNINSKKYQKTIQRKPQNRLGLN-GPDEVKEHPWL | . | . || | |. |. | .... |.|| | ||.. | .| | |. |.|| |..||| . . |.|.||. DWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQ-----IPPQMSNDAWDLIQGL--LQKD--------------PKKRLGTKRDFMEIKNHPFF |
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| Kinase | 7413.AA | RSK | 27-59 | 52 | 3e-06 | 19.51 | In-house | 1-36 (278) | Show / Hide |
Range on Protein: 27-59 Range on HMM: 1-36/278 Sequence Identity: 52% (19 aa) LYVIGRGGFGKVW---KVEHKKTKQLYAMKEMSKAK | | |.||.||| |..|..|.|.|||| .||| LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAK |
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| Kinase | 7413.AA | RSK | 287-308 | 41 | 4e-06 | 18.81 | In-house | 255-278 (278) | Show / Hide |
Range on Protein: 287-308 Range on HMM: 255-278/278 Sequence Identity: 41% (10 aa) QRKPQNRLG--LNGPDEVKEHPWL .| |..||| .. .|.|.|||. HRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | 7413.AA | AktR | 290-308 | 52 | 9e-06 | 18.7 | In-house | 248-268 (268) | Show / Hide |
Range on Protein: 290-308 Range on HMM: 248-268/268 Sequence Identity: 52% (11 aa) PQNRLG--LNGPDEVKEHPWL |..||| ||..|.|.||| PNKRLGYYCNGWEEIKSHPWF |
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| Kinase | 7413.AA | RSK | 288-308 | 52 | 2.2e-05 | 15.42 | In-house | 249-271 (271) | Show / Hide |
Range on Protein: 288-308 Range on HMM: 249-271/271 Sequence Identity: 52% (12 aa) RKPQNRLGL--NGPDEVKEHPWL | |.|||| || ..|.|||. RDPHNRLGAGPNGVEQIKQHPWF |
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| Kinase | 7413.AA | RSK | 210-242 | 36 | 0.00045 | 11.21 | In-house | 192-227 (278) | Show / Hide |
Range on Protein: 210-242 Range on HMM: 192-227/278 Sequence Identity: 36% (13 aa) AADYYAVGVITYECMLGKRPYIG---RTRKELRDQI |.|.. ||. || |..|. | .|||. ..| ACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRI |
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| Kinase | 7413.AA | S_TK_X | 309-370 | 21 | 0.000952 | 7.86 | SMART | 1-79 (79) | Show / Hide |
Range on Protein: 309-370 Range on HMM: 1-79/79 Sequence Identity: 21% (17 aa) RDFPWQKLEN--RELESPFLPKSE----DNFDAKQME----PRDKQDTNPEL-----IQQNQLLLR---RNSVQGYEYEK |.. |.||.| .|.| || || . .|... . . .|... ..||. .. .. |. | RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNE-METEIPPDPFRGFTYVF |
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| Kinase | 7413.AA | CAMK | 300-308 | 33 | 0.019612 | 2.85 | In-house | 417-425 (425) | Show / Hide |
Range on Protein: 300-308 Range on HMM: 417-425/425 Sequence Identity: 33% (3 aa) DEVKEHPWL .....|||. EQCLNHPWM |
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| Kinase | 7413.AA | RSK | 208-242 | 28 | 0.04574 | 3.46 | In-house | 183-217 (271) | Show / Hide |
Range on Protein: 208-242 Range on HMM: 183-217/271 Sequence Identity: 28% (10 aa) SVAADYYAVGVITYECMLGKRPYIGRTRKELRDQI ..|.|.. ||. || | |. ...|... ..| DQACDWWSFGVLMYEMLTGCTPFQNKPRDTPMNII |
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| Kinase | 7413.AA | Pkinase | 284-308 | 20 | 0.094683 | 7.27 | Pfam | 272-293 (293) | Show / Hide |
Range on Protein: 284-308 Range on HMM: 272-293/293 Sequence Identity: 20% (5 aa) KTIQRKPQNRLGLNGPDEVKEHPWL . ....|. |.. ......|||. WCLCKDPKKRPT---AEQILQHPWF |
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