Gene 8897 (Tetrahymena)

8897

Species: Tetrahymena
Alias: 8897, TTHERM_01251240, PreTt08897, 757, 293.m00023
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
8897.AA Protein None 681 None Fasta, JSON
8897.kin_dom Protein Kinase Domain None 260 None Fasta, JSON
8897.NA RNA None 2046 None Fasta, JSON

Protein domain

Protein domains of 8897.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 8897.AA Ciliate-E2-Unclassified 35-294 25 1e-83 284.4 In-house 1-352 (352) Show / Hide 
Range on Protein: 35-294
Range on HMM: 1-352/352
Sequence Identity: 25% (90 aa)

YKVKQTLNSGSFGTVFLAEDENGKLFA-----IKRLQDDNKQLLET------ELTALKSIKGENIVE------------------MVEFFYDQHTQLPLI
||. .....|.||.|....... | ..     .|  |...... ..      |.......|. ....                  ...|...| .| . |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEYCDQGDLRDYQCTKMH---------------CIFNEDEAL-----SIFAQILQGFKSIHEKG-FIHRDLKERNILMKNN----VAKISDFGLAKQLS
|||||..|||..| . ...               .|| | .|.      .|||||||....|.|. .||||.|  |||..||      ||.|||..|.. 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

FN----------------QLTKSRCWTLPYA----APEILQGLSYN----YKVDIWSLGVILFRMLFNSFPFGCYSSDV------------VQLQAINQC
 |                |.....|.|. |     |||.|||  |.    ||.|||||||||. |||. .||......             . .| ....
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

FVSDVFTISKTKRKFTQDISVECV----GIFRKIFVTDCDKRIGFKELYDEPIL
.  ...  .  .... ...| |.      ...|... ...|||.|...   |..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 8897.AA Ciliate-E2 35-294 23 1.9e-81 276.86 In-house 1-365 (365) Show / Hide 
Range on Protein: 35-294
Range on HMM: 1-365/365
Sequence Identity: 23% (91 aa)

YKVKQTLNSGSFGTVFLAED-ENGKLFAIKRLQDDN-----------------KQLLETELTALKSIKGEN-----------------------IVEMVE
||. . . .|.||.|..... ...|.||||. . ..                 |.. . .. ..|... ..                       |..|.|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

FFYDQHTQLPLIVMEYCDQGDLRDYQ---CTKMHCI------FNEDEALSIFAQILQ---------------GFKSIHEKG-FIHRDLKERNILMKNNVA
.|... ..   .|||||..|||.||    ..| ...      |.| |.. |..||||               .....|.|.  ||||.|  |||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----I

KISDFGLAKQLSFN--------------------------------QLTKSRCWTLPYAAPEILQGLS---------YNYKVDIWSLGVILFRMLFNSFP
||.||||.|... .                                ..... |.|..| |||||.| .         |.||.|||||||||..|||. .|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FGCYSSDVVQLQAINQCFVSDVFTISKTKRKFT---------QDISVECVGIFRK----IFVTDCDKRIG-FKELYDEPIL
|          | ...    | .   ..|. ..         ...| ||  ...|    ... | .|||. .... . |..
F----------QQQIKQCKIDFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 8897.AA ULK 35-294 28 5.5e-73 248.79 In-house 1-324 (324) Show / Hide 
Range on Protein: 35-294
Range on HMM: 1-324/324
Sequence Identity: 28% (95 aa)

YKVKQTLNSGSFG-TVFLA--EDEN--GKLFAIKRLQ-----DDNKQ--------LLETELTALKSIK---GEN--IVEMVEFFYDQH-TQLPLIVMEYC
| ... | .|||| .|. .  .. |  ....|.|  .     .....        ||. |   .| .|   ..|  ||.. ..|.... . .  |.||||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNI-YIIMEYC

DQGDLRDYQCTKMHC-------IFNEDEALSIFAQILQGFKSIHEKGFIHRDLKERNILMKNN-------------VAKISDFGLAKQLSFN----QLTK
..|||..|  .. ..       ...|.||...| ||..||| .|... ||||.|  |||..|.             |.||.|||.||..  |    |...
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

SRC------WTLPYAAPEILQGL----SYN-YKVDIWSLGVILFRMLFNSFPFGCYSSDVVQL---QAIN----QCFVSDVFTISKTKRKFT-----QDI
. .       |  | ||.||||.     |. ||.||||||.|.. ||... || ..     .|   . ||    |      ..| ... .|      . |
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQ-----QIYIKNQPIQFPKPPKDPKI

SVECVGIFRKIFVTDCDKRIGFKELYDEPIL
| ||  ..|. .. | ..|| . |... |..
SPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 8897.AA ULK 35-294 29 2.6e-72 246.53 In-house 1-329 (329) Show / Hide 
Range on Protein: 35-294
Range on HMM: 1-329/329
Sequence Identity: 29% (97 aa)

YKVKQTLNSGSFGTVFLA--EDEN---GKLFAIKRLQ---DDNKQ----------LLETELTALKSIK----GEN----IVEMVEFFYDQH-TQLPLIVM
| ... | .||||.|. .  .. .   ....|.| ..    ..|.          ||. |   .| .|    ..|    ||.. ..|.... . .  |.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNI-YIIM

EYCDQGDLRDYQCTKMHC--------IFNEDEALSIFAQILQGFKSIHEKGFIHRDLKERNILMKNN-------------VAKISDFGLAKQLSFN----
|||..|||..|  .. ..        ...|.||...| |||.||| .|... ||||.|  |||..|.             |.||.|||.||... .    
EYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

QLTKSRC------WTLPYAAPEILQGL----SYN-YKVDIWSLGVILFRMLFNSFPFGCYSSDVVQLQAINQCFVS-DVFT--ISKTKRKFTQD-----I
|....         |  | ||.||||.     |. ||.||||||.|.. ||..  || ..     .|| |.. .   ..    | |.. .| .|     |
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

SVECVGIFRKIFVTDCDKRIGFKELYDEPIL
| ||  ..|. .. | ..|| . ||.. |..
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 8897.AA S_TKc 35-294 29 2.4e-69 237.62 SMART 1-231 (231) Show / Hide 
Range on Protein: 35-294
Range on HMM: 1-231/231
Sequence Identity: 29% (81 aa)

YKVKQTLNSGSFGTVFLAEDEN-GKLFAIKRLQDDNKQLLETELTALKSIKGENIVEMVEFFYDQHTQLPLIVMEYCDQ--GDLRDYQCTKMH----CIF
|.. ... .|.||.|... . . |...|||..     . .. |.  ||. . .||| . ..|.|   .   .||||||.  |||.|| . . .    . |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

NEDEALSIFAQILQGFKSIHEKGFIHRDLKERNILMKNNVAKISDFGLAKQLSFNQLTKSRCWTLPYAAPEILQGLSYNY-KVDIWSLGVILFRMLFNSF
.| .| ....||... . .|..|.||||||  |||. . . ||.|||||.||      .. | |. | |||.|   .|.. |.|.||.|.||. ||    
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYP

PFGCYSSDVVQLQAINQCFVSDVFTISKTKRKFTQDISVECVGIFRKIFVTDCDKRIGFKELYD-------EPIL
||        . . ....                   | |.  . ||... | .||..  |.          | .
PFP------QMQMMFKKIG------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 8897.AA Pkinase 35-228 36 1.2e-58 205.94 Pfam 1-212 (293) Show / Hide 
Range on Protein: 35-228
Range on HMM: 1-212/293
Sequence Identity: 36% (78 aa)

YKVKQTLNSGSFGTVFLAEDENG-KLFAIKRLQDDNKQLLET-------ELTALKSIKGENIVEMVEFFYDQHTQLPLIVMEYCDQG----DLRDYQCTK
|...... |||||.|... . .  |..|.|..  ...   .        |.  .|... .|||.. ..|.|   . . .|||||. |    || ||  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

MHCIF--NEDEALSIFAQILQGFKSIHEKGFIHRDLKERNILMK-NNVA----KISDFGLAKQ--LSFNQLTKSRCWTLPYAAPEILQ-GLSYNYKVDIW
.|. |   |.|. ... |||.| . .|..|.||||||  |||.. |..     ||.|||||||  .  |. ....| |..|.|||... |  | .|||.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGVILFRMLFNSFPF
|.|.||. ||.  .||
SCGCILYEMLCGRPPF
Kinase 8897.AA CAMKL 35-294 27 3.1e-58 184.38 In-house 1-297 (297) Show / Hide 
Range on Protein: 35-294
Range on HMM: 1-297/297
Sequence Identity: 27% (83 aa)

YKVKQTLNSGSFGTVFLAED-EN-GKLFAIKRLQDDNKQL------------------LETELTALKSIK---GENIVEMVEFFYDQHT----QLPLIVM
|.. .||  ||||.| ||..  . |.  ||| .  . ...                  .. |   .|...    .||. . | .... .    .   .||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCDQGD--LRDYQCTKMHCI--FNEDEALSIFAQILQGFKSIHEKGFIHRDLKERNILMK-NN--VAKISDFGLAKQLS-F----NQLTKSRCWTLPYA
|||. |.  | || . . |.   . |.||  .| ||. . . .|..| .|||.|  |||   |.  ..||.|||.. .        .|. | .| ..||.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEILQG--LSYN-YKVDIWSLGVILFRMLFNSFPFGCYSSDVVQLQAINQCFVSDVFTISKTKRKFTQDISV-ECVGIFRKIFVTDCDKRIGFKELYDE
||||.||   .|. .||||||.||||. |..  .|| . .       ... ..      | ..  ...  ..| .|  . ||. ... .||.  ...   
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN-K---QGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNH

PIL
| .
PWM
Kinase 8897.AA CAMK 40-294 20 5.8e-58 185.03 In-house 1-425 (425) Show / Hide 
Range on Protein: 40-294
Range on HMM: 1-425/425
Sequence Identity: 20% (88 aa)

TLNSGSFGTVFLAEDE-NG------------KLFAIKRLQ-------------------------------DDNKQLLETELTALKS-------IKGENI
|| .||||.|.|...  ..            . .||| .                                . ... .. |.  .|.       .. .||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VEMVEFFYDQH-----------------TQLPLIVM---EYCDQG----DLRDYQCTKMH-------------CIFNEDEALSIFAQILQGFKSIHEKGF
. . |.. | |                 ..   .||   |||. |    || || . . .               |.|.||  .| ||... . .|... 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKERNILMKNN------------------VAKISDFGLAKQLSF------------------------NQLTKSRCWTLPYAA-PEILQG------
.|||||  |||. .|                    ||.|||.|...                          .|. | .| |..|.| ||.|.|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------LSYNYKVDIWSLGVILFRMLFNSFPFGCYS------------SDVVQLQAINQCFVS-DVFTISKT----KRKFTQDISVE--------CVG
          |..|.|.||.||||. ||   .||   .            .|   .. | ..  . . . .|..    .  .  ||| |        |  
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

IFRKIFVTDCDKRIGFKELYDEPIL
  ||. ..| .||.  ..  . | .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 8897.AA CAMK-Unique 35-294 21 2.1e-50 164.52 In-house 1-363 (363) Show / Hide 
Range on Protein: 35-294
Range on HMM: 1-363/363
Sequence Identity: 21% (81 aa)

YKVKQTLNSGSFGTVFLAED-ENGKLFAIKRLQD-----DNKQL------------------LETELTALKSIKGENIVEMVEF----FYDQH-------
||  . . .|.|| |. . | |.||..|.|...      . . .                  |. |.  .|. . .||.. ...    | |         
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

----TQLP--LIVMEYCDQGDLRDYQCT------------------KMHCIFNE--DEALSIFAQILQGFKSIHEKGFIHRDLKERNILMKNNVA-----
      ||   ||||||. ||| |.                     .. ..|.|   ....|....|.  .  |... .|||||  ||. ....      
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

------------KISDFGLAKQLSFNQLTK---SRCWTLPYAAP--------------EILQGLSYNYKV----DIWSLGVILFRMLFNSFPFGCYSSD-
            |..||||..... |.      ..| |..|.||              |.. .  | ...    ||||||||.. ||. . || | ..| 
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

------VVQLQAINQCFVSDVFTISKTKRKFTQD---ISVECVGIFRKIFVTDCDKRIGFKELYDEPIL
      . ....| .. . ..      ..|  ..   ||.|   .  . ...| |.|.  |||.. . .
DYENHDKEIFECICKGDYCNF------DWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 8897.AA NEK 35-221 30 7e-46 158.74 In-house 1-217 (286) Show / Hide 
Range on Protein: 35-221
Range on HMM: 1-217/286
Sequence Identity: 30% (66 aa)

YKVKQTLNSGSFGTVFLAED-ENGKL-----FAIKRLQDDN-----KQLLE-TELTALKSIKGENIVEMVEFFYDQHTQLPLIVMEYCD-QGDLRDYQCT
|.. ... .||||.|..... ..||      ...|. . .|     || .   |   ||..| .|||.  . |...  .   ||||||.  ||| . . .
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

-KMHC----IFNEDEALSIFAQILQGFKSIHEK-----GFIHRDLKERNILMKNN-----VAKISDFGLAKQLSFN-QLTKS-RCWTLPYAAPEILQGLS
 |..      | |.. . .|.|.. . | .|..       .|||.|  || . .|     ..|| |||..|.|. . .. ..    |  |..||..|. .
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YNYKVDIWSLGVILFRM
||.|.||||||..|. |
YNNKSDIWSLGCVLYEM
Kinase 8897.AA MARK 35-294 28 4.6e-45 145.33 In-house 1-262 (262) Show / Hide 
Range on Protein: 35-294
Range on HMM: 1-262/262
Sequence Identity: 28% (79 aa)

YKVKQTLNSGSFGTVFLAEDEN-GKLFAIKRLQ-----D-DNKQLLETELTALKSIKGENIVEMVEFFYDQHTQL-PLIVMEYCDQGDLRDYQCTKMHCI
||...|.  ||...| || . . |. .||| ..     |  ... .. |.  .|... .||... . .   ..|    ..|||.  |.|.||   . .  
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FNEDEALSIFAQILQGFKSIHEKGFIHRDLKERNILM-KNN--VAKISDFGLAKQLSFNQLTKSRCWTLPYAAPEILQGLSYN-YKVDIWSLGVILFRML
  |.||  || ||. . .  |.|. .|||.|  |||. .|.   .||.|||.. .   .|. .. | |.||.||||...  |. .|||||||||.|. |.
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

FNSFPFGCYSSDVVQLQAINQC--FVSDVFTISKTKRKFTQDISVECVGIFRKIFVTDCDKRIGFKELYDEPIL
  .|||             ...  ..   . | . | ..   .|.||  . ..........|.  .|.   | .
CGYFPFD------------GDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 8897.AA STE 35-222 23 8.3e-40 138.26 In-house 1-262 (359) Show / Hide 
Range on Protein: 35-222
Range on HMM: 1-262/359
Sequence Identity: 23% (64 aa)

YKVKQTLNSGSFGTVFLAEDEN----------------GKLFAIKRLQ--------------------DDNKQLLETELTALKSIK--GENIVEMVEFFY
..  . . .|.||||..| . .                |...|||..                     ....| .. |.  .|  .   .|||.    ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DQ------HTQLPLIVMEYCDQGDLRDYQCTKMHC------------IFNEDEALSIFAQILQG-FKSIHEKGFIHRDLKERNILMKNNVAKISDFGLAK
.       ...|  |.|||.| | |.|   .|. |             |.|..   |  |||.|  . .|... ||||.|  |||.    .|..|||...
KEGHNHKNDDEL-WICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCG

QLSFN-----------------QLTKSRCWTLPYAAPEILQG------LSYNYKVDIWSLGVILFRML
||. .                 | ... . |  . |||..|.        |..|.||||||  .  |.
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMA
Kinase 8897.AA TyrKc 35-292 23 6.8e-16 34.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 35-292
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

YKVKQTLNSGSFGTVFLAEDENGKLFAIKRLQDDNKQLLETELTALKSI--KGENIVEMVEFFYDQ-----HTQLPLIVMEYCDQGDLRDY-QCTKMHCI
 . ...| .| ||.|....       |.| |..| .. .  |.  ....  . .||| ..    .|       . ..|||||.. |||.|| . .. .  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--

FNEDEALSIFAQILQGFKSIHEKGFIHRDLKERNILMKNNV-AKISDFGLAKQLSFN-------QLTKS----RCWT-LPYA--APEILQGLSYNYKVDI
.. .. ||.  || .|   .|.|..|||||  ||.| ..|  .|||||||.. .          .  ..     . | ||.   ||| ..   .. | |.
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSLGVILFRMLFNSFPFGCYSSDVVQLQAINQCFVSDVFTISKTKRKFTQDISVE--------CVGIFRKIFVTDC-----DKRIGFKELYDEP
|| || .. ..  ..    |. .. |       ..|.   | . |. .  ..  .        |     .   ..|     ..|  |.|.... 
WSFGVCMWEIF--TYGQQPYPGMIQQ-------MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase 8897.AA Pkinase_Tyr 147-219 36 2.9e-11 38.78 Pfam 128-205 (270) Show / Hide 
Range on Protein: 147-219
Range on HMM: 128-205/270
Sequence Identity: 36% (30 aa)

HEKGFIHRDLKERNILMK-NNVAKISDFGLAKQL-SFNQL-TKSR------CWTLPYAAPEILQGLSYNYKVDIWSLGVILF
..|..|||||  ||.| . |||.||.|||||. . .  .  .|.        |.    ||| ..   .. | |.|| || ..
ESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYGKFTTKSDVWSFGVLMW
Kinase 8897.AA Pkinase_Tyr 35-118 26 7e-06 20.45 Pfam 1-97 (270) Show / Hide 
Range on Protein: 35-118
Range on HMM: 1-97/270
Sequence Identity: 26% (26 aa)

YKVKQTLNSGSFGTVFLAEDE-----NGKLFAIKRL--QDDNKQ-----LLETELTALKSI-KGENIVEMVEFFYDQHTQ-LPLIVMEYCDQGDLRDY
 .  ..| .|.||.|....       ..   |.| |  . . .|     ... |.  .|.. . .||| ..   .||  .  ..|||||.  |||.||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY