Gene 9974 (Tetrahymena)

9974

Species: Tetrahymena
Alias: 143, 3828.m01238, PreTt09974, 9974, 5.m00325, TTHERM_00074310
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E9

Sequence

Name Sequence Type Origin Length Description Download
9974.AA Protein None 498 None Fasta, JSON
9974.kin_dom Protein Kinase Domain None 295 None Fasta, JSON
9974.NA RNA None 1497 None Fasta, JSON

Protein domain

Protein domains of 9974.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 9974.AA Ciliate-E9 13-307 55 2.8e-231 747.87 In-house 1-298 (298) Show / Hide 
Range on Protein: 13-307
Range on HMM: 1-298/298
Sequence Identity: 55% (164 aa)

YIVHKKIATGTQGSVVLATDKDSRSRYAIKIYKQKQQKD-YFTKYVKLEMEKLKQSKSQ-YIIRLEDILVDANYMKPDNSVTTINAIVMEYASYGNFHDL
|.||..||.||||.|.||.|...|..|||||.|..|..| .|.||...||..|.|.... |||.|.||....||||......|||.||||||..|...||
YRVHRNIAQGTQGQVKLAIDMQTRKKYAIKIMKHQQMNDEMFFKYFQREMNILNQVQPHRYIIQLQDICYNINYMKCHGQKFTINYIVMEYANNGCLFDL

I-YLTGPFNEKVAKYYFKQLILGINYLHNEQNICHRDLKPDNMLLNENLEMKICDLAMSATLSNQLTTTVGNLQFQAPELHKLNQVEEINNQQQEQQVVG
| ..|..|||.||||||||||..|.|.|..||||||||||.|||...|..|||||..|||...|..|...||||.|..|.|..||....|||||..|...
ISMHTEKFNENVAKYYFKQLIDSIEYMHQYQNICHRDLKPENMLIDKNYNMKICDFGMSAQCRNDKTQVIGNLQCQPKENHGTNQYNPPNNQQQQYQGIK

YNGRATDIFSAGVILYLMLTGTYPFFSTKCYNDTTIDKIWQSYRIKAQAASNCSNSEDQKKSSFIPLSQEVIDLINQMLQKEPLNRISLAEIISHPWL
|||...||||||.||..|....||||.|.||||||||||||.|||......||.|..||......|..||.||..|.|||..|.||||..||..|||.
YNGQKFDIFSAGCILFMMVMNQYPFFHTNCYNDTTIDKIWQYYRIFFFCMDNCQNFWDQFIYNYRPEEQEFIDMMNWMLQQDPQNRISIQEIRMHPWM
Kinase 9974.AA S_TKc 13-307 26 7.5e-70 239.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-307
Range on HMM: 1-231/231
Sequence Identity: 26% (82 aa)

YIVHKKIATGTQGSVVLATDKDSRSRYAIKIYKQKQQKDYFTKYVKLEMEKLKQSKSQYIIRLEDILVDANYMKPDNSVTTINAIVMEYASY--GNFHDL
| ...||  |. |.| ....|..  ..|||| |         . .. |.. ||. .  .|..| |. .|           .   .||||..   |. .|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-----------DHLYMVMEYCDGDLGDLFDY

IYLTGP------FNEKVAKYYFKQLILGINYLHNEQNICHRDLKPDNMLLNENLEMKICDLAMSATLSNQLTTTVGNLQFQAPELHKLNQVEEINNQQQE
|   |.      |.| .|..|..|......|.|.  .|.||||||.| ||.|  . ||||  ... |    || .| . . |||.               
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL--------------

QQVVGYNGRATDIFSAGVILYLMLTGTYPFFSTKCYNDTTIDKIWQSYRIKAQAASNCSNSEDQKKSSFIPLSQEVIDLINQMLQKEPLNRISLAEIIS-
    ||.... |. | |.||| ||.|  ||         .......  .                       |.|..|.|...|||.| .|..  |.   
----GYGKCKCDWWSCGCILYEMLCGYPPFP--------QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQD

------HPWL
      |||.
EWDIKCHPWF
Kinase 9974.AA CAMK 18-307 20 2.2e-66 212.66 In-house 1-425 (425) Show / Hide 
Range on Protein: 18-307
Range on HMM: 1-425/425
Sequence Identity: 20% (91 aa)

KIATGTQGSVVLATDKDSR------------SRYAIKIYKQKQQKD-------------------------YFTKY-VKLEMEKLKQSK-------SQYI
.. .|. | | |...| .              ..||||.. |. ||                          ...  |. |.| .|. .          |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLEDILVDANYMKPDNSVT----TINA----------IVM---EYASYG----NFHDLIYLTGP---------------FNEKVAKYYFKQLILGINYL
|.| ..  |..| |     |    | .           .||   ||.| |       | |   |.               |.|. |..||.|.. ...|.
IKLYEVYEDPHYFK-N---TNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYC

HNEQNICHRDLKPDNMLLNEN-----------------LEMKICDLAMSATLSN--------------------------QLTTTVGNLQFQA-PELHKL
|.   |.||||||.| ||..|                    ||.|  ... .                             ..| .| . . | ||. . 
HSHN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG

NQVEEINNQQQEQQVVGYNGRATDIFSAGVILYLMLTGTYPFFSTK------------CYNDTTIDKIWQSYRIKAQA------------ASNCSNSEDQ
..  .   .    .   | |...|. |.||||| ||.|..|| . .            .....    .   |.                  .. |..   
KGHCNMQ-N-ATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDE---

KKSSFIP--LSQEVIDLINQMLQKEPLNRISLAEIISHPWL
    | .  .|||..|||..|||..| .|...... .|||.
----F-HHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 9974.AA Ciliate-E2-Unclassified 13-307 23 3.1e-61 209.73 In-house 1-352 (352) Show / Hide 
Range on Protein: 13-307
Range on HMM: 1-352/352
Sequence Identity: 23% (87 aa)

YIVHKKIATGTQGSVVLATDKDSR--------SRYAIKIYKQKQQKDYFTKYVKLEMEKLK----------------QSKSQYIIRLEDILVDANYMKPD
|...|.| .| .|.| .. .|.          . . |.  ||...||   .  ..||...|                .... .|......  | ...   
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNI---

NSVTTINAIVMEYASYGNFHDLIYLTGP-----------------FNEKVAK-----YYFKQLILGINYLHNEQNICHRDLKPDNMLLNENL---EMKIC
        |||||. .|. .. |   .                  | |. ||     .||.|...|..||| ..||.|||.||.| |...|    . ||.
-------YIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKII

DLAMSATLSNQ------------------LTTTVGNLQFQ----APELHKLNQVEEINNQQQEQQVVGYNGRATDIFSAGVILYLMLTGTYPFFSTKCYN
|.  |  . ..                  ..|..|.....    |||. . .. ..                . ||.| ||||| ||.|.|||....|. 
DFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA------------YKCDIWSLGVILYEMLFGYYPFYDNNCEQ

DTTIDKIWQSY--RIKAQAASNCSNSEDQKKSSF----IPLSQEVIDLIN----QMLQKEPLNRISLAEIISHPWL
. .  ..|.    ..| .    . .  ...|...      .|.|..|.||    .||.| | .||.. .|. |||.
HQQLITQWI-NNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 9974.AA Ciliate-E2 13-307 22 2.7e-59 202.2 In-house 1-365 (365) Show / Hide 
Range on Protein: 13-307
Range on HMM: 1-365/365
Sequence Identity: 22% (92 aa)

YIVHKKIATGTQGSVVLATDKDSRSRY------------------AIKIYKQKQQKDYFTKYVKLEMEKLK----------------QSKSQYIIRLEDI
|...||| .|..||| .....  . ..                  .||||  |..| .  ...| |   ..                | .. .||.. . 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LV--DANYMKPDNSVTTINAIVMEYASYGNFHDLIYLT-----------GPFNEKVAKYYFKQLIL---------------GINYLHNEQNICHRDLKPD
    | |..           .||||...|.  |.|.             ..|.|| .||..||..                ...|||.. ||.|||.||.
FQEKDDNNIY----------LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPE

NMLLNENLEMKICDLAMSATLS----------------------------------NQLTTTVGNLQFQAPELHKLNQVEEINNQQQEQQVVGYNGRATD
| |.      ||.|. .|  ..                                  |.  |..|.. ..||| ..  . .      |.|.   . . . |
NILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ----QKQK---GYDYKCD

IFSAGVILYLMLTGTYPFFSTKCYNDTTIDKIWQSYRIKAQAASNCSNSEDQKKS----------------------SFIPLSQEVIDLINQ----MLQK
|.|.||||| ||.| .||                               ..|.|                       |.  .|||..|||..    ||||
IWSLGVILYEMLFGKPPF-------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQK

EPLNRIS-LAEIISHPWL
.| .||.   .|. |||.
DPEKRITGWEQILNHPWF
Kinase 9974.AA Pkinase 13-307 26 3.1e-53 187.95 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-307
Range on HMM: 1-293/293
Sequence Identity: 26% (88 aa)

YIVHKKIATGTQGSVVLATDKDSRSRYAIKIYKQKQQKDYFTKYVKL--EMEKLKQSKSQYIIRLEDILVDANYMKPDNSVTTINAIVMEYASYG----N
| ...||  |. |.| ....|... ..|.|| | . .|. . ..  .  | . .|  .. .|.|| |.  |     .|.       .||||.  |     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----KDHIY-----MVMEYCEGGLYVMD

FHDLIY--LTGPF--NEKVAKYYFKQLILGINYLHNEQNICHRDLKPDNMLLNENLEM----KICDLAMSA---TLSNQLTTTVGNLQFQAPELHKLNQV
 .|.|     |.|   |...| |..|.. |..|.|. ..|.||||||.| |...| .     ||||   ..   . .|..|| .| . . |||...    
LFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIR----

EEINNQQQEQQVVGYNGRATDIFSAGVILYLMLTGTYPFFSTKCYNDTTIDKIWQSYRIKAQAASNCSNSEDQKKSSFIP---------------LSQEV
              | |.. |..|.|.||| ||.|  || .     |. .|...  .||.      . ...|  ... |.               .|.| 
-----------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-HDQMQMICRIM-----GPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEEC

IDLINQMLQKEPLNRISLAEIISHPWL
.|.|. .|.| |  |.. ..|  |||.
KDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 9974.AA CAMKL 13-189 26 4.5e-38 118.99 In-house 1-204 (297) Show / Hide 
Range on Protein: 13-189
Range on HMM: 1-204/297
Sequence Identity: 26% (58 aa)

YIVHKKIATGTQGSVVLATD-KDSRSRYAIKIYK-QKQQKDYFTKY------------VKLEMEKLKQSK---SQYIIRLEDILVDANYMKPDNSVTTIN
|.. | . .|. | | |||. .  . ..||||.. .| ..| ..|             .. |.. .|. .    . ||.| ... . ..           
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEH-----------

A-------IVMEYASYGN--FHDLIYLT----GPFNEKVAKYYFKQLILGINYLHNEQNICHRDLKPDNMLLNENL--EMKICDLAMSAT---L----SN
        .||||.| |.   .| |       |.. |. |. ||.|.. ..||.|.   |.|||.||.| || ||     ||.|  .|.          .
DIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQ

QLTTTVGNLQFQAPEL
 |.|  | . ..|||.
KLKTFCGSPPYMAPEI
Kinase 9974.AA Ciliate-C1 97-164 57 2e-35 89.03 In-house 105-172 (328) Show / Hide 
Range on Protein: 97-164
Range on HMM: 105-172/328
Sequence Identity: 57% (40 aa)

IVMEYASYGNFHDLIYLTGP-FNEKVAKYYFKQLILGINYLHNEQNICHRDLKPDNMLLNENLEMKICD
||.||.| |   | | ..|| ||| .|.|||.||| .| |.| ..||||||||| | ||.||   || |
IVFEYCSNGELFDYIAHKGPLFNEELARYYFHQLINVIQYIH-QNNICHRDLKPENILLDENFNLKIAD
Kinase 9974.AA RAD53 13-234 29 4.8e-35 101.45 In-house 1-241 (305) Show / Hide 
Range on Protein: 13-234
Range on HMM: 1-241/305
Sequence Identity: 29% (74 aa)

YIVHKKIATGTQGSVVLATDKDSRSRYAIKIYKQKQ-----QKD-YFTKYVKLEMEKLKQSKSQYIIRLEDILVDANYMKPDNSVTTINAIVMEYASYGN
|.. |.. .|  |.| || .|. ....|||| . |.      ..  ... |  | | ||  . . |||..|| ...          .   .|.|... | 
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTP---------QKYYYMVLELMTGGE

FHDLIYLTGP----FNEKVAKYYFKQLILGINYLHNEQNICHRDLKPDNMLLNENL------------------EMKICDLAMSATLSNQ--LTTTVGNL
. . |   ..    |.|  .||||.|......|||. ..||||||||.| |.|..                     || |  .| .....  ..|  | .
LFNKIVSNKRCQMGFDEDTCKYYFYQMCDAVKYLHD-NGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTP

QFQAPE-LHKL--NQVEEINNQQQEQQVVGYNGRATDIFSAGVILYLMLTGTYPF
|. ||| . .   |   | .  | .   ||| ... |. |.|.|||..|.|. ||
QYVAPEVITSKGHNCYHENEERQVQ---VGY-TKKVDCWSMGCILYICLCGYPPF
Kinase 9974.AA MARK 13-164 32 4e-31 99.13 In-house 1-149 (262) Show / Hide 
Range on Protein: 13-164
Range on HMM: 1-149/262
Sequence Identity: 32% (52 aa)

YIVHKKIATGTQGSVVLATDKDSRSRYAIKIYKQKQQKD-YFTKYVKLEMEKLKQSKSQYIIRLEDILV--DANYMKPDNSVTTINAIVMEYASYGNFHD
| . | | .|. . | ||..| .. ..|||||. ..  |    | |. |.| .|. .  .||.| .. .  . .         .|. ..||||| |. .|
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQH--------QIY-LIMEYASGGELYD

LIYLT--GPFNEKVAKYYFKQLILGINYLHNEQNICHRDLKPDNMLLNENL--EMKICD
 |.    |.  |. |. .|.|.. ..||.|.   |.|||.||.| |. ||    .||.|
YIKAHPNGRLHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIID
Kinase 9974.AA CAMKK 119-238 31 3.8e-29 89.29 In-house 175-330 (396) Show / Hide 
Range on Protein: 119-238
Range on HMM: 175-330/396
Sequence Identity: 31% (49 aa)

EKVAKYYFKQLILGINYLHNEQN-------------------ICHRDLKPDNMLLNENL---EMKICDLAMSATLSNQLTT--------------TVGNL
|  |. || . |.|. ||||.|.                   |.|||.||.| |..|.      ||.|   |  .. |  |              |.|  
EDYAWKYFRDCIKGLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTP

QFQAPELHKL-NQVEEINNQQQEQQVVGYNGRATDIFSAGVILYLMLTGTYPFFSTK
 |.||||    ||.|  |.         |.|.| || ..|| || ...|. ||....
AFMAPELCSKENQKENYNGYK-YRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNN
Kinase 9974.AA AMPK 13-164 35 8.1e-26 73.68 In-house 1-143 (254) Show / Hide 
Range on Protein: 13-164
Range on HMM: 1-143/254
Sequence Identity: 35% (55 aa)

YIVHKKIATGTQGSVVLATDKDSRSRYAIKIY-KQKQQKDYFTKYVKLEMEKLKQSKSQYIIRLEDILVDANYMKPDNSVTTINAI--VMEYASYGNFHD
||. |.| .|| | | ..| .  .   ||||  ||| ...   . .. | . ||  . . ||.| ...           . |   |  ||||.| |   |
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVI-----------IETPTDIFMVMEYVSGGELFD

LIYLTGPFNEKVAKYYFKQLILGINYLHNEQNICHRDLKPDNMLLNENLEMKICD
 |   |  .|. |. .|.| | |. |.|.  .| |||||| |.||..| . || |
YIVKHGRLQEREACRFFQQIISGVEYCHR-HMIVHRDLKPENLLLDHNKNIKIVD
Kinase 9974.AA CAMKL 210-307 29 1.1e-23 72.39 In-house 212-297 (297) Show / Hide 
Range on Protein: 210-307
Range on HMM: 212-297/297
Sequence Identity: 29% (31 aa)

YNGRATDIFSAGVILYLMLTGTYPFFST---KCYNDTTIDKIWQSYRIKAQAASNCSNSEDQKKS-SFIP----LSQEVIDLINQMLQKEPLNRISLAEI
|.|...|| |.||||| |..|..||      |                  | ..|  . . ....  ..|    .| ...||| .|||. |  |... .|
YDGPKVDIWSCGVILYAMVCGYLPFDDDTYNK------------------QGKDNI-YLYWKIMCGYYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQI

ISHPWL
 .|||.
MNHPWM
Kinase 9974.AA Ciliate-C1 277-307 58 3.8e-18 43.21 In-house 298-328 (328) Show / Hide 
Range on Protein: 277-307
Range on HMM: 298-328/328
Sequence Identity: 58% (18 aa)

SQEVIDLINQMLQKEPLNRISLAEIISHPWL
|.| .|||||||  .| .||.|.||..|||.
SNEFMDLINQMLAYNPQKRITLQEIKCHPWY
Kinase 9974.AA CAMKK 276-307 43 2.3e-13 38.33 In-house 365-396 (396) Show / Hide 
Range on Protein: 276-307
Range on HMM: 365-396/396
Sequence Identity: 43% (14 aa)

LSQEVIDLINQMLQKEPLNRISLAEIISHPWL
.| . .|||..||.|.|  ||....|..|||.
ISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV
Kinase 9974.AA AMPK 276-307 50 9.3e-13 34.26 In-house 223-254 (254) Show / Hide 
Range on Protein: 276-307
Range on HMM: 223-254/254
Sequence Identity: 50% (16 aa)

LSQEVIDLINQMLQKEPLNRISLAEIISHPWL
||.|. |||..|||. |..||.  .|  |||.
LSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 9974.AA RAD53 277-307 41 2.5e-12 32.51 In-house 275-305 (305) Show / Hide 
Range on Protein: 277-307
Range on HMM: 275-305/305
Sequence Identity: 41% (13 aa)

SQEVIDLINQMLQKEPLNRISLAEIISHPWL
|.|. |||..||. .| .|.. .|...|||.
SEEAKDLIKWMLCVDPEKRYTIDEALNHPWM
Kinase 9974.AA Ciliate-C1 209-235 48 4.9e-11 24.34 In-house 236-262 (328) Show / Hide 
Range on Protein: 209-235
Range on HMM: 236-262/328
Sequence Identity: 48% (13 aa)

GYNGRATDIFSAGVILYLMLTGTYPFF
.|.| . |||..||||  |..|. ||.
RYCGSKVDIFACGVILFCMVHGHPPFH
Kinase 9974.AA MARK 210-234 52 8.2e-11 31.75 In-house 182-206 (262) Show / Hide 
Range on Protein: 210-234
Range on HMM: 182-206/262
Sequence Identity: 52% (13 aa)

YNGRATDIFSAGVILYLMLTGTYPF
|.|...|| | ||.|| |..|..||
YDGPKVDIWSLGVVLYFMVCGYFPF
Kinase 9974.AA TyrKc 13-307 18 8.3e-09 -80.29 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-307
Range on HMM: 1-280/280
Sequence Identity: 18% (62 aa)

YIVHKKIATGTQGSVVLATDKDSRSRYAIKIYKQKQQKDYFTKYVKLEMEKLKQS--KSQYIIRLEDILVD--------ANYMKPDNSVTTINAIVMEYA
    ||.  |  | |...| |      |.|  |         .    |.. ...   . . |.||  . ..          .|           |||||.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLM-----------IVMEYM

SYGNFHDLIYLTGP-FNEKVAKYYFKQLILGINYLHNEQNICHRDLKPDNMLLNENLEMKICDLAMSATLSNQ-LTTTVGNLQFQAPELHKLNQVEEINN
..|. .| .  ..| .. |   ..  |   | .|||   |. ||||   | |..||. .||.|  .|  . .   .                        
PHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-----------------------

QQQEQQVVGY--NGR--------------------ATDIFSAGVILYLMLTGTYPFFST----KCYNDTTIDKIWQSYRIKAQAA----SNCSNSEDQKK
  ..  ..    .|.                    ..|..| || .. ..|   .  .     .. |.  | .. | || .  .     |          
ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------

SSFIPLSQEVIDLINQMLQKEPLNRISLAEIISHPWL
  |   ..|. ... |  . .| .| . .||  |  .
--FVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 9974.AA MARK 276-307 37 1.3e-08 24.49 In-house 231-262 (262) Show / Hide 
Range on Protein: 276-307
Range on HMM: 231-262/262
Sequence Identity: 37% (12 aa)

LSQEVIDLINQMLQKEPLNRISLAEIISHPWL
.| |  .||...|.  |  |... || .|||.
VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 9974.AA AMPK 210-234 60 2e-08 21.19 In-house 176-200 (254) Show / Hide 
Range on Protein: 210-234
Range on HMM: 176-200/254
Sequence Identity: 60% (15 aa)

YNGRATDIFSAGVILYLMLTGTYPF
|.|. .|| | ||||| || |. ||
YCGPEVDIWSCGVILYAMLCGYLPF
Kinase 9974.AA Ciliate-C1 13-49 24 3.1e-05 8.95 In-house 1-41 (328) Show / Hide 
Range on Protein: 13-49
Range on HMM: 1-41/328
Sequence Identity: 24% (10 aa)

YIVHKKIATGTQGSVVLATDKDSRSRYAIKIYKQ----KQQ
..  |.| .| .  | .. . ..   ||.|. |.    .||
MKIMKTIGHGYTCKVFYCKMPNNQKVYAVKQFKNEYTSQQQ
Kinase 9974.AA CAMKK 13-50 34 8.2e-05 10.72 In-house 1-43 (396) Show / Hide 
Range on Protein: 13-50
Range on HMM: 1-43/396
Sequence Identity: 34% (15 aa)

YIVHKKIATGTQGSVVLATDKDS-RSRYAIKIYKQ----KQQK
|   |.|  |. | | ||....   . |||||..     |..|
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLK