Gene 29238 (Tetrahymena)
29238
Group:
Other
Family:
Ciliate-F1
Sequence
Protein domains of 29238.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 29238.AA | Ciliate-F1 | 205-356 | 50 | 3e-93 | 316.1 | In-house | 1-174 (174) | Show / Hide |
Range on Protein: 205-356 Range on HMM: 1-174/174 Sequence Identity: 50% (88 aa) IRNIIQNQFRYQLKELIGKG------AYG---LVYAID-LDHNQNQAIKIQINQSSNAAEFK----------KCEELQNYALQSLDGDILHFFKCFQIQD | | ||....|..| .|| .||.|| ..|||||...||...|||...|| ||...|.|..|..|.||.|||||||.|. IHNSGCVHRDYQTDNIIKMGNNFLFTDYGESEYVYNIDNFHHNQNQTFRIQQRFSSNQTYFKPLLRECYDNLKCNQSQQYYHQPFDSDIYHFFKCFQQQQ SYSK--EILDFFIMERGEKNLKQLTQQANIKNNMNGQNEFHHYWNKQEIRNLFMGIMRNVSFLHSYNYYHRDIK ||.| ...|||||||..||..|.|||.||..|||.|..|||||.|.|.||.||..||||.|.|.||||||||| SYMKGMNKADFFIMERDPKNAYQETQQNNINHNMNKQRYFHHYWYKYECRNIFMSMMRNVEFKHMYNYYHRDIK |
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| Kinase | 29238.AA | S_TKc | 215-541 | 13 | 6.8e-09 | -46.52 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 215-541
Range on HMM: 1-231/231
Sequence Identity: 13% (45 aa)
YQLKELIGKGAYGLVY-AIDLDHNQNQAIKIQINQSSNAAEFKKCEELQNYALQSLDGDILHFFKCFQIQDSYSKEILDFFIMERGEK---NLKQLTQQA
|.. ..|||||.| || ... . .. |||| . . |.| | .. |.. ...|| . .|... ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR
NIKNNMNGQNEFHHYWNKQEIRNLFMGIMRNVSFLHSYNYYHRDI--------KQTYYLIDFNVSEKIEQVLPLAVKLEKAKDKATLRKQDVLSGTPGYL
. . . ... . ..| .. | . . ..|| . |||. . . ..|| .. .. . . ||| |.
GRHGL-------RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL----------------------TTFCGTPWYM
TPQWDMKYQEIKAQKKDPNKKFNKNEWMGIHDPFKSDIYSMGVVFLQFLNNVKVAQYDGFEKFNPSKDQKLAYPLASQVSNILLQKEDIKVNQYFTQTHQ
| ....|.|..| |... .| . . .. |. .
APEVL------------------------GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG---------------------------------
FLMNDQIYEVENLLVAMLESKETDRISTLKLSL-----ICQLYF
|. ... .|. ..|.. .. | .|
------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
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| Kinase | 29238.AA | Ciliate-A9 | 215-244 | 30 | 3.6e-07 | 12.18 | In-house | 1-33 (392) | Show / Hide |
Range on Protein: 215-244 Range on HMM: 1-33/392 Sequence Identity: 30% (10 aa) YQLKELIGKGAYGLVY-AIDLD--HNQNQAIKI . . . ||.||.| |. ..|. .| |.|. FEPIKIIGEGAFGCVIQCRDIQQEDKQEYAVKV |
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| Kinase | 29238.AA | MLCK | 215-230 | 43 | 7.6e-07 | 13.52 | In-house | 1-16 (257) | Show / Hide |
Range on Protein: 215-230 Range on HMM: 1-16/257 Sequence Identity: 43% (7 aa) YQLKELIGKGAYGLVY || .|..|.|..| |. YQIHEELGRGKFGIVH |
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| Kinase | 29238.AA | STE11 | 215-243 | 43 | 1e-06 | 20.37 | In-house | 1-30 (303) | Show / Hide |
Range on Protein: 215-243 Range on HMM: 1-30/303 Sequence Identity: 43% (13 aa) YQLKELIGKGAYGLVY-AIDLDHNQNQAIK .|..|.|||||.| || ....| .. |.| WQKGEIIGKGAFGTVYKCMNVDTGELMAVK |
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| Kinase | 29238.AA | Meta | 215-229 | 66 | 1e-06 | 15.15 | In-house | 1-15 (287) | Show / Hide |
Range on Protein: 215-229 Range on HMM: 1-15/287 Sequence Identity: 66% (10 aa) YQLKELIGKGAYGLV |.|.| ||||.||.| YRLMEEIGKGSYGVV |
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| Kinase | 29238.AA | CDK-Unclassified | 215-243 | 36 | 2e-06 | 17.33 | In-house | 1-30 (324) | Show / Hide |
Range on Protein: 215-243 Range on HMM: 1-30/324 Sequence Identity: 36% (11 aa) YQLKELIGKGAYGLVY-AIDLDHNQNQAIK | . .|.|..|.|. |||.. .. ||| YRMQCKYGEGTFGCVCKAIDFQTQKHVAIK |
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| Kinase | 29238.AA | Ciliate-B2 | 436-444 | 88 | 3e-06 | 10.69 | In-house | 189-197 (197) | Show / Hide |
Range on Protein: 436-444 Range on HMM: 189-197/197 Sequence Identity: 88% (8 aa) FKSDIYSMG |.||||||| FQSDIYSMG |
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| Kinase | 29238.AA | STE20 | 215-244 | 40 | 8e-06 | 17.54 | In-house | 1-35 (288) | Show / Hide |
Range on Protein: 215-244 Range on HMM: 1-35/288 Sequence Identity: 40% (14 aa) YQLKELIGKGAYGLVY-AIDLDHNQN----QAIKI |.| | ||.|.|| || |.. . .. |||. YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKK |
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| Kinase | 29238.AA | Ciliate-E3 | 215-257 | 35 | 1.2e-05 | 13.94 | In-house | 1-48 (202) | Show / Hide |
Range on Protein: 215-257 Range on HMM: 1-48/202 Sequence Identity: 35% (17 aa) YQLKELIGKGAYGLVY-AIDLDHNQNQAIKIQINQSSNA----AEFKK | . ..|.| .|.|| | | || ||| .| | . .|.| YTVQQILGCGQFGRVYKAFDFQNNQDVAIKAIICQNQQNEGVGEQFQK |
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| Kinase | 29238.AA | CK1-Unclassified | 215-244 | 38 | 1.9e-05 | 12.08 | In-house | 1-31 (244) | Show / Hide |
Range on Protein: 215-244 Range on HMM: 1-31/244 Sequence Identity: 38% (12 aa) YQLKELIGKGAYGLVY-AIDLDHNQNQAIKI |...| || |. | .| .|... |.. |||. YRVIEKIGQGSFGEIYKCINMQTNEEVAIKL |
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| Kinase | 29238.AA | Ciliate-E3 | 438-451 | 57 | 2.2e-05 | 13.06 | In-house | 189-202 (202) | Show / Hide |
Range on Protein: 438-451 Range on HMM: 189-202/202 Sequence Identity: 57% (8 aa) SDIYSMGVVFLQFL ||.||.|.||.| SDYYSVGAVFCQLC |
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| Kinase | 29238.AA | Ciliate-F1 | 433-449 | 52 | 5.8e-05 | 14.34 | In-house | 82-98 (174) | Show / Hide |
Range on Protein: 433-449 Range on HMM: 82-98/174 Sequence Identity: 52% (9 aa) HDPFKSDIYSMGVVFLQ |.||.||||... .|.| HQPFDSDIYHFFKCFQQ |
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| Kinase | 29238.AA | Ciliate-B2 | 215-257 | 27 | 0.000109 | 6.84 | In-house | 1-48 (197) | Show / Hide |
Range on Protein: 215-257 Range on HMM: 1-48/197 Sequence Identity: 27% (13 aa) YQLKELIGKGAYGLVYAID----LDHNQNQAIKIQIN-QSSNAAEFKK | | . |.|| |... . . |. |.||. | | .. |. . YYLCKYINKGGCGFICEGYKKHSIREYQDLAFKIYFNKQDCDKEEIQH |
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| Kinase | 29238.AA | Ciliate-F1 | 510-537 | 21 | 0.000111 | 13.31 | In-house | 147-174 (174) | Show / Hide |
Range on Protein: 510-537 Range on HMM: 147-174/174 Sequence Identity: 21% (6 aa) YEVENLLVAMLESKETDRISTLKLSLIC ||. |.. |.. | . .. .. .| YECRNIFMSMMRNVEFKHMYNYYHRDIK |
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| Kinase | 29238.AA | Ciliate-A9 | 327-356 | 43 | 0.005871 | 1.89 | In-house | 123-152 (392) | Show / Hide |
Range on Protein: 327-356 Range on HMM: 123-152/392 Sequence Identity: 43% (13 aa) NKQEIRNLFMGIMRNVSFLHSYNYYHRDIK | |||. || |...|. | |||.| NEQEISQIMKCIMSAVMYMHQKNICHRDLK |
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| Kinase | 29238.AA | CK1-Unclassified | 341-356 | 50 | 0.032448 | 2.36 | In-house | 116-131 (244) | Show / Hide |
Range on Protein: 341-356 Range on HMM: 116-131/244 Sequence Identity: 50% (8 aa) NVSFLHSYNYYHRDIK .. .||. |. ||||| RIEYLHNKNFIHRDIK |
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| Kinase | 29238.AA | CDK-Unclassified | 328-356 | 34 | 0.077915 | 1.66 | In-house | 120-148 (324) | Show / Hide |
Range on Protein: 328-356 Range on HMM: 120-148/324 Sequence Identity: 34% (10 aa) KQEIRNLFMGIMRNVSFLHSYNYYHRDIK ...||| . . .||. ||||| MCQIRNFMHQMLEGIAYLHCNKIMHRDIK |
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| Kinase | 29238.AA | STE20 | 343-356 | 57 | 0.189451 | 1.42 | In-house | 131-144 (288) | Show / Hide |
Range on Protein: 343-356 Range on HMM: 131-144/288 Sequence Identity: 57% (8 aa) SFLHSYNYYHRDIK ..||| .. ||||| DYLHSNHIIHRDIK |
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| MORN | 29238.AA | MORN | 632-654 | 34 | 0.000629 | 19.02 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 632-654 Range on HMM: 1-23/23 Sequence Identity: 34% (8 aa) YNGTWDKDLPHGEGKYNFFQGNY | |.| ....||.|.| . |.. YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | 29238.AA | MORN | 656-675 | 30 | 10.436311 | 3.7 | Pfam | 1-20 (23) | Show / Hide |
Range on Protein: 656-675 Range on HMM: 1-20/23 Sequence Identity: 30% (6 aa) YIGEFYYGVFYGQGTIYYNN | ||. |.. |.|. .. . YEGEWKNGKMHGHGVYTWPD |
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