Gene 29450 (Tetrahymena)

29450

Species: Tetrahymena
Alias: PreTt29450, TTHERM_00264840, 23.m00346, 795, 29450
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-F2

Sequence

Name Sequence Type Origin Length Description Download
29450.AA Protein None 543 None Fasta, JSON
29450.kin_dom Protein Kinase Domain None 85 None Fasta, JSON
29450.NA RNA None 1632 None Fasta, JSON

Protein domain

Protein domains of 29450.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 29450.AA Ciliate-F2 135-251 42 2.8e-47 163.37 In-house 2-146 (200) Show / Hide 
Range on Protein: 135-251
Range on HMM: 2-146/200
Sequence Identity: 42% (62 aa)

NYSFVYSNFCFYQMLKRTNQNEYTSQVIQNKY-----LAPEISN--KNKQIDIKANVYSLGVILLELFFGKRHFTNETEDACIEQQLQ------NQQNEE
 |  .  |  | | ..    | | |  |.  |     |.|||..  |.||||.|..||...||....||.|.||..||||.||.||||      |||.||
QYVGILGNGLFGQQIQAYSEN-YQSVAIKIIYSKNSGLEPEIKQSTKYKQIDNKQHVYQIHVIVYNPFFNKYHFVQETEDCCIKQQLQSCKLTDNQQYEE

IQKFIN--------------IIISSMIKKSPEQR--LDPSQLIQIL
||.|||              |.|..||...|.||  .|..||||||
IQQFINGLAELENLGLIHGDIKIENMIYNRPKQRFMFDDFQLIQIL
Kinase 29450.AA Ciliate-E2 166-249 24 3.4e-13 41.63 In-house 253-361 (365) Show / Hide 
Range on Protein: 166-249
Range on HMM: 253-361/365
Sequence Identity: 24% (30 aa)

YLAPEISN--------KNKQIDIKANVYSLGVILLELFFGKRHFTNETEDACIEQQLQNQQNEEIQKFIN------------------------IIISS-
|.|||| |        | |. | |. ..|||||| |. |||. |            .|.... .|. . .                         .|.  
YMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKF

---MIKKSPEQRLD-PSQLIQ
   |..| ||.|.. ..|...
GKRMLQKDPEKRITGWEQILN
Kinase 29450.AA Ciliate-C5 84-263 29 3.8e-13 39.37 In-house 76-260 (260) Show / Hide 
Range on Protein: 84-263
Range on HMM: 76-260/260
Sequence Identity: 29% (56 aa)

SCTLKEI-----SERNELDIHQICSITQQLLNGLIEIEQEQF-NLFINPDNILYNKENYSFVYSNFCFYQMLKRTNQNEYTSQVIQNKYLAPEISNKNKQ
||.||.|      ..  | . ||  .  |.     .|.|...    . |.||||. .   |  ...   . .|   .  |  .    || |||| ..|  
SCNLKDIMQSFFDQKKTLPLNQIIGFAIQMSTVFEKIQQNNLIHSDVKPENILYDSQEKCFNLCDYGESKSFKDGSK-TYDLKGFTRKYAAPEITDDNGF

IDIKANVYSLGVILLELFFGKRHFTNETEDACIEQ-QLQN-QQNEEIQKFINIIISSMIKKSPEQRLDPSQLIQILQENFKYNESKRT
 .|| ..| ||.|||||  ||  | .. . . | . .| |  ..... . || ||  |. | |..|.|  .| . | |     ||. .
FNIKYDIYGLGIILLELTLGK--FLEDEDCTFIRNGKLPNYISKNALYQDINQIIIKMLEKMPQNRIDSFELTKQLNELRLKLESQFI
Kinase 29450.AA Ciliate-E2-Unclassified 124-249 20 1e-10 33.44 In-house 170-348 (352) Show / Hide 
Range on Protein: 124-249
Range on HMM: 170-348/352
Sequence Identity: 20% (36 aa)

INPDNILYNKENYSFVYSNFCFYQMLK-----------------RTNQNEYTSQVIQNKYL----APEISNKNKQID---IKANVYSLGVILLELFFGKR
| |.|||......   |   . ..  |                 .. |.......  . |.    |||.  .... .   .|. ..|||||| |. ||..
IKPENILFDNNGK-NYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYY

HFT--NETEDAC------------IEQQLQNQQNEEIQKFIN----IIIS------------SMIKKSPEQRLDPSQLIQ
 |   |.... .            . .| ..|.| ...|| .     ..|            .|.|| |..|....|...
PFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 29450.AA Ciliate-E1 21-185 21 9.4e-10 28.38 In-house 14-202 (202) Show / Hide 
Range on Protein: 21-185
Range on HMM: 14-202/202
Sequence Identity: 21% (42 aa)

QYQFNEKYMINERVRMQLQFK----QRVIRSKQQQRLYFCDKKYLLKTYDIMNSLQLQTFFLVNQLCSCTLKEISE--------------RNELDIHQIC
|.. |.. ..   . .. ...    | .|.  ..    |  ..|... .|.  . |.... .....|.|.||.  .               |.... |..
QQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKM

SITQQLLNGLIEIEQEQFNLF-INPDNILYNKENYSFVYSNFCFYQMLKRTNQNEYTSQVIQNKYLAPEISN-------KNKQIDIKANVY
.|. ||. ||||..|  .  . |.|.|||.|..   .||. |   . ||  .....     ...|  ||  |       ||..|..| ..|
QIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY
Kinase 29450.AA Ciliate-B2 78-188 26 3e-09 17.81 In-house 78-197 (197) Show / Hide 
Range on Protein: 78-188
Range on HMM: 78-197/197
Sequence Identity: 26% (32 aa)

LVNQLCSCTLK-EIS----ERNELDIHQICSITQQLLNGLIEIEQEQ-FNLFINPDNILYNKENYSFVYSNFCFYQMLKRTNQNEYTSQVIQNKYLAPEI
|. . | | || |.     .. .     .. .  ||..|||..       | |.|.|||  ...  .||..|    . |  ||. . ..  . ||  || 
LIMEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNG-NYVYCDFGISSIKK-DNQQIKIKGFTK-KYASPEQ

SNKN------KQIDIKANVYSLG
 ..        .|| .. .||.|
MECDHNQTFVTNIDFQSDIYSMG
Kinase 29450.AA Pkinase 166-251 16 7.9e-09 32.3 Pfam 177-293 (293) Show / Hide 
Range on Protein: 166-251
Range on HMM: 177-293/293
Sequence Identity: 16% (19 aa)

YLAPEISNKNKQIDIKANVYSLGVILLELFFGKRHFTNE------TEDACIEQQLQNQQNEEIQ-----------------------KFINIIISSMIKK
|.|||. .... .. |. ..|.|.|| |...|.  | ..      .....|.. .. .  ....                       .    .|.....|
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

SPEQRLDPSQLIQI--L
 |..|. . |. |   .
DPKKRPTAEQILQHPWF
S_TKc 29450.AA S_TKc 9-256 12 1.2e-08 -50.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-256
Range on HMM: 1-231/231
Sequence Identity: 12% (36 aa)

KDQKDIISS-------LCQQYQFNEKYMINERVRMQLQFKQRVIRSKQQQRLYFCDKKYLLKTYDIMNSLQLQTFFLVNQLCSC---TLKEISERNE---
 .  ..| .       .|.    .... | .         ....|  |  .    . ... | ||.. .   . ...|  .|.    .|... ...    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK---HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LDIHQICSITQQLLNGLIEIEQEQF--------NLFINPDNI------LYNKENYSFVYSNFCFYQMLKRTNQNEYTSQVIQNKYLAPEISNKNKQ
    ..  .......|....|  . . ..        |....  .|      |  .                        |...    |.|||.     .
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----------------------TTFCGTPWYMAPEVL----G

IDI-KANVYSLGVILLELFFGKRHFTNETEDACIEQQLQNQQNEEIQKFINIIISSMIKKSPEQRLDPSQLIQ----ILQENFK
 .  |. ..|.|.|| |.. |.  |    ... . ...        . ... .|. . .| ||.|.   .. |    | .  . 
YGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 29450.AA TKL-ciliate1 166-251 24 3.4e-08 24.13 In-house 180-279 (279) Show / Hide 
Range on Protein: 166-251
Range on HMM: 180-279/279
Sequence Identity: 24% (25 aa)

YLAPEISN----KNKQIDIKANVYSLGVILLELFFGKRHF------TNETEDACIEQ---QL--QNQQNEEIQKFINIIISSMIKKSPEQRLDPSQLIQI
. |||.       |..| .|. .|..|... .| | |  |       |.  . | .     |  |       | |.|...  .  . | .| . ...|||
WMAPEQMDPHIFPNYPINEKIDIYAYGIVMYILCFRKTPFQQKMSVINIMCYWCEFPGRPNLGPQFIHFDCPQNFHNLMM-RCWCQNPNKRPNFNEIIQI

L
|
L
Kinase 29450.AA TKL 166-251 13 5.1e-07 21.32 In-house 239-364 (364) Show / Hide 
Range on Protein: 166-251
Range on HMM: 239-364/364
Sequence Identity: 13% (17 aa)

YLAPEISNKN---------------KQIDIKANVYSLGVILLELFFGKRHFTNETE-------------DACIEQQLQ--------N----QQNEEIQKF
..|||. ...               .. . |. ||| |..| |.. ..| . .. .               ... .|.        |    .... . . 
WMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPS

INIIISSMIKKSPEQRLDPSQLIQIL
.  ..    .  ||.|.  ......|
MKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 29450.AA C8 165-191 38 7e-07 20.04 In-house 196-226 (226) Show / Hide 
Range on Protein: 165-191
Range on HMM: 196-226/226
Sequence Identity: 38% (12 aa)

KYLAPEISNK----NKQIDIKANVYSLGVIL
.|.|||| .|    .||  |.  ..|.|..|
AYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 29450.AA Ciliate-A8 54-113 24 3e-06 18.29 In-house 55-124 (151) Show / Hide 
Range on Protein: 54-113
Range on HMM: 55-124/151
Sequence Identity: 24% (17 aa)

YFCDKKYLLKTYDIMNSLQLQTFFLVNQLCSC--------TLKEISE--RNELDIHQICSITQQLLNGLI
.. ..|| |....    ...  .  | ..|.|        .| .|.|   | ... ||  .| |||..|.
KIKNEKYILQIIECIQDKEQGFIAIVTEFCDCFDFYKKKENLASILENNLNKFTFEQIVALTYQLLKCLL
Kinase 29450.AA Ciliate-A8 124-139 43 0.000438 10.87 In-house 136-151 (151) Show / Hide 
Range on Protein: 124-139
Range on HMM: 136-151/151
Sequence Identity: 43% (7 aa)

INPDNILYNKENYSFV
|.|.||||.. .  |.
IKPQNILYSWSKNQFI
Kinase 29450.AA Ciliate-F2 67-116 26 0.0076 6.47 In-house 63-112 (200) Show / Hide 
Range on Protein: 67-116
Range on HMM: 63-112/200
Sequence Identity: 26% (13 aa)

IMNSLQLQTFFLVNQLCSCTLKEISERNELDIHQICSITQQLLNGLIEIE
|.  . . . ..|. .  | .|.. .   |   |.   .||..||| |.|
IVYNPFFNKYHFVQETEDCCIKQQLQSCKLTDNQQYEEIQQFINGLAELE