Gene 26298 (Tetrahymena)

26298

Species: Tetrahymena
Alias: 26298, 911, TTHERM_00753300, 122.m00100, PreTt26298
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: NAK

Sequence

Name Sequence Type Origin Length Description Download
26298.AA Protein None 686 None Fasta, JSON
26298.kin_dom Protein Kinase Domain None 267 None Fasta, JSON
26298.NA RNA None 2061 None Fasta, JSON

Protein domain

Protein domains of 26298.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 26298.AA NAK 41-308 40 1.1e-150 506.3 In-house 1-299 (299) Show / Hide 
Range on Protein: 41-308
Range on HMM: 1-299/299
Sequence Identity: 40% (122 aa)

IQEEKILSEGGFGYIWKAY---------DVNTRESFALKRMICQ-GEDRVQIARRELKNFESLPNHPNIIRFYGGSIT-PT--RDGCIALFLMELCDGGS
...||.| ||||.|.....         .....|..|||||||. .|.. ....||..... |..|.||.......|. .   .... ...|||.|..||
YTVEKYLAEGGFSYVYLVQDNYINHPDNPNSNGEKYALKRMICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYCCHGS

LFDLM-SQTM-PNK-IPERKLIHIIYEAAKGIRALHQAYP--PITHRDIKIENILQS----GGVYKLCDFGSCSTQTIDFRNVPKSEYEN-YEDLFNKST
|.||| ...| ... ..|.. ..|... ..|..|.||..|  ||.||||||||||.|     | ||||||||..|..|...|  ...|.. ..|..|| |
LWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIKIENILLSESHHDGNYKLCDFGSMTTAIIQPENRWEAQYRSMVQDWINKYT

TLMYRPPEMCDPSKKMLVDTQVDVWMLGCVLYTIAFYIHPFVD------SSKLAIVDANYR--FPADSKYSQKFHDFIRHMITPDPSFRPTIHDVIQIC
|.|||.|||||  ... .|..||.|.|||.||...||.||| |      ||||||...||.  .| .|.|||..||.||.|.||||. ||.|..|... 
TPMYRAPEMCDLYSNCPIDEKVDIWALGCMLYKMCFYTHPFEDCYQRHDSSKLAIQNGNYKYSIPDNSRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL
Kinase 26298.AA NAK-Unclassified 41-309 25 2.2e-73 250.08 In-house 1-405 (405) Show / Hide 
Range on Protein: 41-309
Range on HMM: 1-405/405
Sequence Identity: 25% (102 aa)

IQEEKILSEGGFGYIWKAY--------D------VNTRESFALKRMICQGEDRVQIARRELKNFESLPNHPNIIRFYGGSITPTRDG---CIALFLMELC
  . ..| ||||...  .         |       .. .  .||||||| |..   ..||  ..  . |||||.   . .|   ...      . |||.|
YTIVRYLAEGGFSFVYLVKFSKYINPPDNTASVPHSNSNMYCLKRMICQDEESLNTMKREIDVMKRFRNHPNIVKYIDHHIMRENHNNQSYEVFMLMEYC

DGGSLFDLMS------QTM--PNKIPERKLIHIIYEAAKGIRALHQAYP--------------------------------------------PITHRDI
 .||| |.|       |     ..  |..   | .  . || ..||  |                                            |. ||||
SRGSLQDFMNNQRTIYQRLTEQTRFHEQECLQIMSDVCQGIQCMHQHQPRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIPLIHRDI

KIENILQS-----------------------------------------------------------GGVYKLCDFGSCSTQTIDFRNVPKSEYENYEDL
||||.| .                                                           .| |||||||||..  | ..|  . |  . .| 
KIENVLFCNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSEHNGIYKLCDFGSCCECIITIEN--RQEMQYLQDW

FNKSTTLMYRPPEMCDPSKKMLVDTQVDVWMLGCVLYTIAFYIHPFVDSSKLA-------IVD--ANYRFPADSKYSQKFHDFIRHMITPDPSFRPTIHD
 |. ||. ||.||| |       |  .|.| ||| ||...||. || ..  |.       |    ..| ||  ..|| ..|  |. |. .||. ||.|  
INMHTTPQYRAPEMIDLYRCCPIDEKIDIWALGCFLYKMCFYTTPFEMCGQLHNASVTYKILHGLGKYEFPSNHNYSNQLHNLIKIMLNEDPIQRPNIYQ

VI-QICE
|. .||.
VLNHICQ
Kinase 26298.AA GAK 44-308 32 1.2e-58 193.52 In-house 4-277 (277) Show / Hide 
Range on Protein: 44-308
Range on HMM: 4-277/277
Sequence Identity: 32% (89 aa)

EKILSEGGFGYIWKAYDVNTRESFALKRMICQGEDRVQIARRELKNFESLPNHPNIIRFYGGSITPT----RDGCIALFLMELCDGGSLFDLMS-QTMPN
.... ||||. .. | || |   .|||||.   .   .    |      |  |.||. | . | .      . .   | |||.| ...| |..   .   
RCVIAEGGFAFVYVAQDVQTGREYALKRMLSHDMQANRAIINEICMMKKLQGHENIVQFCDASYISREESNQSQAEYLLLMEYCKFSQLVDCLKRMECYK

KIPERKLIHIIYEAAKGIRALHQAYPPITHRDIKIENILQSG-GVYKLCDFGSCSTQTIDFRN-VPKSEYENYEDLFNKSTTLMYRPPEMCDPSKKMLVD
 .     . |.|  .  .  .|   ||| |||||||| | .. .  ||||||| .|  .        ..    || ... || |||.|||||      . 
PFSCDCVLRIFYQMCRAVQHMHSQKPPIIHRDIKIENFLIGNQKTIKLCDFGSATTKSHYPDYSWSAQKRSMVEDEMFRHTTPMYRSPEMCDLYSNWPIG

TQVDVWMLGCVLYTIAFYIHPFVDSSKLAIVDANYR--FPA-DSKYSQKFHDFIRHMITPDPSFRPTIHDVIQIC
 ..|.| .|| ||....  ||| |..||.|. .||    |  | .| . ||| || . ...|  |..|  |..  
HKQDIWAMGCMLYFMCYRQHPFEDGAKLRIINGNYMKPIPPQDNQY-MCFHDLIRACLQVNPDERLDIAMVVEYM
Kinase 26298.AA BIKE 41-307 33 2.6e-55 190.08 In-house 1-267 (267) Show / Hide 
Range on Protein: 41-307
Range on HMM: 1-267/267
Sequence Identity: 33% (91 aa)

IQEEKILSEGGFGYIWKAYDVNTRESFALKRMICQGEDRVQIARRELKNFESLPNHPNIIRFYGGSITPTRDG-CIALFLMELCDGGSLFDLMSQTMPNK
.  |. | ||||  .. . | .    .|||||  . |   ....|| .    .  | ||. .   .|... .| .  . ||| | .  . ..| | .   
VTVEEQLAEGGFAMVFLVRDHKG-NKCALKRMYVNNEHDLNVCCREHQIMKQCSGHKNIVGYVDCYINCIGNGVWECMILMEYCRH-QVVNMMNQRLQQG

--IPERKLIHIIYEAAKGIRALHQAYPPITHRDIKIENILQSGGV---YKLCDFGSCSTQTIDFRNVPKSEYENYEDLFNKSTTLMYRPPEMCDPSKKML
    |    .|  . .  .  ||.   || ||| |.||||..      | ||||||  ...    |. |   .  .|   | ||. || ||| |      
QYFTEQEVLQIFCDVCEAVSRLHHCQTPIIHRDLKVENILLHDHGPPHYVLCDFGSATNKFL---NPQKHGVNYVKDEIEKYTTMCYRAPEMIDLYSGKE

VDTQVDVWMLGCVLYTIAFYIHPFVDSSKLAIVDANYRFPADSKYSQKFHDFIRHMITPDPSFRPTIHDVIQI
. |  |.| ||| ||   |.  ||  |. ||| | |. .|  ||||.  |  || |  ||.  || |  | ..
ITTKADIWALGCMLYKLCFFCLPFGESQ-LAICDGNFTIPDNSKYSREMHCLIRYMLEPDMEKRPDIYQVSHV
Kinase 26298.AA S_TKc 41-307 22 1e-41 145.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 41-307
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

IQEEKILSEGGFGYIWKAYDVNTRESFALKRMICQGEDRVQIARRELKNFESLPNHPNIIRFYGGSITPTRDGCIALFLMELCDG--GSLFDLMSQTMPN
 .  ... .|.||  .|.....| . .|.|..        . .|||..  ..  .||||...|.   .    ... .. ||.|||  |.|||.. .  ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD----DHLYMV-MEYCDGDLGDLFDYIKKRGRH

K----IPERKLIHIIYEAAKGIRALHQAYPPITHRDIKIENILQSGGVYKLCDFGSCSTQTIDFRNVPKSEYENYEDLFNKSTTLMYRPPEMCDPSKKML
.    .||    ...|. ....  .|.    | |||.| |||| .  . |.||||..                          |. |..||..       
GLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE-HIKICDFGLARQL------------------TTFCGTPWYMAPEVL------G

VDT-QVDVWMLGCVLYTIAFYIHPFVDSSKLAIVDANYRFPADSKYSQKFHDFIRHMITPDPSFRPTIHDVIQ----------I
 ..  .|.| .||.||  .    ||      .. .           |. . ||||.. . ||. |||. .. |          .
YGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 26298.AA Pkinase 41-306 23 3.5e-35 125.49 Pfam 1-289 (293) Show / Hide 
Range on Protein: 41-306
Range on HMM: 1-289/293
Sequence Identity: 23% (74 aa)

IQEEKILSEGGFGYIWKAYDVNTRESFALKRMICQGEDR--VQIARR--ELKNFESLPNHPNIIRFYGGSITPTRDGCIALFLMELCDGG----SLFDLM
.. .... .|.||  .|.....|.. .|.|..  ..|.    |..||  |..   .| |||||.|.|.   .   .. |  . ||.|.||    .|||..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED---KDHIY-MVMEYCEGGLYVMDLFDYI

SQTMPNKI--PERKLIHIIYEAAKGIRALHQAYPPITHRDIKIENILQS-GGVY----KLCDFGSCSTQTIDFRNVPKSEYENYEDLFNKSTTLMYRPPE
|  . ...  .|. .....|. ..|.  .|.    | |||.| |||| .  |.     |.||||..              | |.. .     |. |..||
STWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------Y-NNS-MTTFCGTPWYMAPE

MCDPSKKMLVDTQVDVWMLGCVLYTIAFYIHPFVDS------SKLAIVDANYRFPADSKYS-----------------------QKFHDFIRHMITPDPS
 .   .    .. ||.| .||.||  ..   || ..      ....... . . | .. ..                       . . |||. ....||.
VIR--GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPK

FRPTIHDVIQ
 |||.... |
KRPTAEQILQ
Kinase 26298.AA TKL-ciliate1 118-308 23 5.5e-33 110.24 In-house 76-279 (279) Show / Hide 
Range on Protein: 118-308
Range on HMM: 76-279/279
Sequence Identity: 23% (50 aa)

FLMELCDGGSLFDLMSQTMP--NKIPERKLIHIIYEAAKGIRALHQAYPPITHRDIKIENILQSGG-VYKLCDFGSCSTQTI-DFRNVPKSEYENYEDL-
. ||.| .|..||... .    . |..   . .... |.|.  ||.  .|. |||.|..||| .    || |.|..    .| ||   ..   ..  |. 
IIMEHCHKGTMFDICHRKHSQIYMIKWQHRMRWCKDIAQGMQYLHMRQNPLIHRDLKMQNILYDEPYQYKICNFPHV---KIADF---HRIRNCSFQDMQ

--FNKSTTLMYRPPEMCD----PSKKMLVDTQVDVWMLGCVLYTIAFYIHPFVDSSKLAIVDANYRFPADS------------KYSQKFHDFIRHMITPD
    . || ... ||  |    | .   . ...|.. .| |.|  .|   ||   .|.  ..     .               ...| ||...  .   .
NEMQRNTTFHWMAPEQMDPHIFPNYP--INEKIDIYAYGIVMYILCFRKTPF--QQKMSVINIMCYWCEFPGRPNLGPQFIHFDCPQNFHNLMMRCWCQN

PSFRPTIHDVIQIC
|  ||    .||| 
PNKRPNFNEIIQIL
Kinase 26298.AA CAMK 46-306 17 2.2e-32 101.12 In-house 1-421 (425) Show / Hide 
Range on Protein: 46-306
Range on HMM: 1-421/425
Sequence Identity: 17% (75 aa)

ILSEGGFGYIWKAYDVNTR------------ESFALKRMICQGEDR----------------------------VQIARRELKNFESLP------NHPNI
.| .|.||   .... ||             . .| | .  .  .                              .  |||..   .|       .||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRFYG----GSI--------TPTR-----DGCIALFL--MELCDGG----SLFDLMSQTMP-------------NKIPERKLIHIIYEAAKGIRALHQAY
|..|     ..         | ..     | .. ...  ||.|.||     |||   .  .              ...||   ...   . ... .|.  
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

PPITHRDIKIENILQSG------------------GVYKLCDFGSCSTQTIDFRNVPKSEYENYEDLFNK--------------STTLMYRP-PEMCDPS
  | |||.| |||| .                   .  |..|||     . .  |  .|.|.. | . ..                |. | . ||.   .
--IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGK

K-----------KMLVDTQVDVWMLGCVLYTIAFYIHPFVDSS-----------------KLAIVDANYRFPADS----------------------KYS
.           |  .. ..|.| .|..||.      || ...                 .  |  ..|.|| .                       . |
GHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVS

QKFHDFIRHMITPDPSFRPTIHDVIQ
|   |.||.| ..||. |.||... .
QECKDLIRKMLQVDPEKRMTIEQCLN
Kinase 26298.AA Ciliate-E2 41-306 19 9.7e-31 102.73 In-house 1-361 (365) Show / Hide 
Range on Protein: 41-306
Range on HMM: 1-361/365
Sequence Identity: 19% (74 aa)

IQEEKILSEGGFGYIWKAYDVNTRE-----------------------SFALKRMICQGEDRVQIARRELKNFE------------SLPNHPNIIRFYGG
.   |.. .|.|| ..|. . ....                        .|.|.|. ..   .    ....  .            .. ||||||..|  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

SITPTRDGCIALFLMELCDGGSLFDLMS--QTMPNKIPE-------RKLIHIIYEAAK---------------GIRALHQAYPPITHRDIKIENILQSGG
 .. ... .   . ||.|.||.|||..   ..  |...|       .. ..|... ..               ... ||.  . | ||||| ||||    
FQEKDDNNIY--LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN-IIHRDIKPENILF---

VYKLCDFGSCSTQTIDFRNVPKSEYENYEDLFNK----------------------STTLMYRPPEMCDPSK------KMLVDTQVDVWMLGCVLYTIAF
  |..||| .  ...|  |  .   .... .| |                        |..| .||.    |      .   |...|.| ||..||   |
-IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

YIHPFVDSSKLAIVDANYRFP----------------ADSKYSQKFHDFIRH----MITPDPSFRPT-IHDVIQ
  .||       | . ...||                   | ||.  |.|.     |.  ||. |.| . ....
GKPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 26298.AA TKL 47-308 17 7.8e-30 104.6 In-house 1-364 (364) Show / Hide 
Range on Protein: 47-308
Range on HMM: 1-364/364
Sequence Identity: 17% (66 aa)

LSEGGFGYIWKAYDVNTR--------ESFALKRMICQG----------------------EDRVQIARRELKNFESL----PNHPNIIRFYGGSITPTRD
. .|||| ..|..  ...        .  | |..  .                       .|. .   |. ...| .     .||||..|.| .. |. .
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-GCI--------ALFLMELCDGGSLFDLMSQTMPNKIPERKLIHIIYEAAKGIRALHQAY------PPITHRDIKIENILQSG-GV--------------
  |.          . ||.|.||||....           .........|.|.  ||.        ||| |||.| .|||    .               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

YKLCDFGSC--STQTIDFRNVPKSEYE-----NYEDLFNKST-TLMYRPPEMCDPS-------------KKMLVDTQVDVWMLGCVLYTIAFYIHPFVDS
 |.|||| .   .|. .     ... |     |..   ..   |. . .||. . .             |.   ....||.  | ||. |.   .|. | 
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

SK-------------LAIVDANYRFPAD------------SKYSQKFHDFIRHMITPDPSFRPTIHDVIQIC
                 ..| ..| | .            .   . . . . .   .||. ||.  ..... 
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 26298.AA STE 42-303 22 5.6e-28 95.94 In-house 1-350 (359) Show / Hide 
Range on Protein: 42-303
Range on HMM: 1-350/359
Sequence Identity: 22% (81 aa)

QEE-KILSEGGFGYIWKAYDVN---------------TRESFALKRMICQGE-----------------DRVQIARRELKNFESLPN-HPNIIRFYGGSI
.|  ... .|.||   ||....               | | .| |.|  . .                 . .|   .|.|    . . ||||...||  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TP---TRDGCIALFLMELCDGGSLFDLMSQT-MPNK-----------IPERKLIHIIYEAAKG-IRALHQAYPPITHRDIKIENILQSGGVYKLCDFGSC
     . ..      ||..||||| |.. .. ...|           .||  ...|...  ||    ||.    | |||||  |||      |||||| |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL----VKLCDFGVC

STQTIDFRNVPKSEYENYEDLFN---------KS-----TTLMYRPPEMCDP-SKKML---VDTQVDVWMLGCVLYTIAFYIHPFVDSSKL----AIV--
.  | . .|    .     .  .         |.     |   .  ||. .. ...      ||..|.| |||..   |   .|. | . .    .|   
GQLTDSMANI-Q-S-----NN-IIDCIETMQQKRNTFVGTP--WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFN

--------------DANYRFPAD-----------------SKYSQKFHDFIRHMITPDPSFRPTIHD
              .   ..| .                 .|.|..|.|||..  . ||. ||| ..
YHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 26298.AA Ciliate-E2-Unclassified 41-306 18 4.8e-25 83.83 In-house 1-348 (352) Show / Hide 
Range on Protein: 41-306
Range on HMM: 1-348/352
Sequence Identity: 18% (67 aa)

IQEEKILSEGGFGYIWKAYDVNTRESFALKRMICQGEDRVQIARR---------ELKNFE-------------SLPNHPNIIRFYGGSITPTRDGCIALF
    |.. .|||| ..|... .. . .|.| |. . .. ... ..         |..| .             .| |||.... .   .  ... ..  .
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY--I

LMELCDGGSLFDLMSQTMP---------------NKIPERKLI-----HIIYEAAKGIRALHQAYPPITHRDIKIENILQS-GG---VYKLCDFGSCS--
 ||.|.||.|.. ... .                ....|.. .     .....  .|.  ||.    | ||||| |||| . .|     |..|||...  
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

-TQTIDFRNV--PKSEYENYEDLFNKSTTLMYR----PPEMC--DPSKKMLVDTQVDVWMLGCVLYTIAFYIHPFVD--------------------SSK
 ..  .  .   .|  .  .. .  .. |..|     .||.       ..    ..|.| ||..|| . |  .|| |                      .
QQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA-YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLY

LAIVDANYRFP------ADSKYSQKFHDFIR----HMITPDPSFRPTIHDVIQ
  | . |. ||      .. . |..  |||.     |.  .|. |.|. ....
QNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN
Kinase 26298.AA TyrKc 41-308 20 2.2e-11 -38.63 SMART 1-280 (280) Show / Hide 
Range on Protein: 41-308
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)

IQEEKILSEGGFGYIWKAYDVNTRESFALKRMICQGEDRVQIARRELKNFESL-PNHPNIIRFYGGSITPT------RDGCIALFLMELCDGGSLFDLMS
|. .|.| || || ..|.      .  | | .       ..  .||..   .| ..||||.|.||  ...          .|   .||....|.| |   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMI---VMEYMPHGDLKDYLR

QTMPNKIPERKLIHIIYEAAKGIRALHQAYPPITHRDIKIENILQSGGV-YKLCDFGSCSTQTID-FRNVPKSEYENYEDLFNK----STT--LMYR--P
 . |. .. ..|... . .|.| . ||.   .. |||.   |.| . .   | .||| .   . |  .          .|   |    ..   | .|  .
KHRPK-LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-------ESKDYYRKKEHKGGKTMLPIRWMA

PEMCDPSKKMLVDTQVDVWMLGCVLY-----TIAFYIHP----FVDSSKLAIVDANYRFPADSK--------YSQKFHDFIRHMITPDPSFRPTIHDVIQ
||     ..    |. |||. | ...         |  .      ..  .. |.. || |             ... .. ..     ||. |||  ....
PECI---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

IC
. 
CF
Kinase 26298.AA Pkinase_Tyr 41-155 27 1.3e-05 19.65 Pfam 1-123 (270) Show / Hide 
Range on Protein: 41-155
Range on HMM: 1-123/270
Sequence Identity: 27% (34 aa)

IQEEKILSEGGFGYIWKAYDV----NTRESFALKRM--ICQGED--RVQIARRELKNFESLPNHPNIIRFYGGSITPTRDGCIALFLMELCDGGSLFDLM
|.  | | || || ..|..      ||.   | | .   .  |.  |    | |.|   .|..||||.|.||  .   . .   .  ||.. .|.| |  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYL

SQT--MPNKIPERKLIHIIYEAAKG
 .    .....   |... .. |||
RKHREDKQPLTMKDLLQMCWQIAKG