Gene 26436 (Tetrahymena)

26436

Species: Tetrahymena
Alias: 48.m00199, TTHERM_00429960, PreTt26436, 3831.m01541, 109, 26436
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
26436.AA Protein None 779 None Fasta, JSON
26436.kin_dom Protein Kinase Domain None 271 None Fasta, JSON
26436.NA RNA None 2340 None Fasta, JSON

Protein domain

Protein domains of 26436.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 26436.AA ULK 8-281 25 9.4e-81 274.59 In-house 1-324 (324) Show / Hide 
Range on Protein: 8-281
Range on HMM: 1-324/324
Sequence Identity: 25% (85 aa)

YILLEHICQGTFG-EIHKGRNLIS---KEAVAVKTIQLEQFLNDSVLRD------MIINEIQALKKLE---DPN--IIRMIKMLKSS--NNIYLIYEFLQ
|.| . ...|.||   .|||| ..   ...||.| |.. .. ... ...      ...|||| .|||     ||  |.........|  ||||.|.|. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GRNLKKLLNERHH---------LSEMEAVQIFQQICKGFQRLQAEKIIKKNLNSHNVHIIEHQSE-----NQQISYEVKLKHFFICKSSSSNSSSSRKFE
| .|.........         |||.||.|.|.||| ||. |. ..||   .   |  | ..|       ... .. .|.  |  .|.  .|. .  .. 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNNNMEQQMCQ

QFLN-----EKFHYVAPELLV----NSQADSTVCDIFSAGVVLYEMLLGSLPFEKYANNKEDL--------------TEFYSNNDIQDVIAQDISHLSER
...|         | ||..|     . . ..  |||.| |...|||| |. ||... .|...|              .. . . ......  .. ..|. 
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP--KDPKISPE

IQLLLNRMLVVEQDERITWEEIFEIVAQ
.. |. |||......||.|||||..   
CKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 26436.AA ULK 8-281 25 6.4e-80 271.83 In-house 1-329 (329) Show / Hide 
Range on Protein: 8-281
Range on HMM: 1-329/329
Sequence Identity: 25% (83 aa)

YILLEHICQGTFGEIHKGRNLISK----EAVAVKTIQLEQFLNDSVLRD------MIINEIQALKKLE----DPN----IIRMIKMLKSS--NNIYLIYE
|.| . ...|.||  .|||| ..|    |.||.| |..... ... ...      ...|||. .|||      .|    |.........|  ||||.|.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FLQGRNLKKLLNERHH----------LSEMEAVQIFQQICKGFQRLQAEKIIKKNLNSHNVHIIEHQSE-----NQQISYEVKLKHFFICKSSSSNSSSS
. .| .|.........          |||.||.|.|.||. ||. |. ..||   .   |. | ..|       ... .. .|.  |  .|. .... . 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNDNMEQ

RKFEQFLN-----EKFHYVAPELLV----NSQADSTVCDIFSAGVVLYEMLLGSLPFEKYANNKEDLTEFYSNNDIQDVIAQ-------------DISHL
. .  ..|         | ||..|     . . ..  |||.| |...|||| |  ||... .|...|   ... .......|             .. ..
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

SERIQLLLNRMLVVEQDERITWEEIFEIVAQ
|. .. |. |||......||.|||.|..   
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 26436.AA Ciliate-E2-Unclassified 8-281 20 3.5e-40 137.07 In-house 1-352 (352) Show / Hide 
Range on Protein: 8-281
Range on HMM: 1-352/352
Sequence Identity: 20% (75 aa)

YILLEHICQGTFGEIHKGRNLISKEAVAVKTIQLEQFLNDSVLRDM--IINEIQALKKLE-------------------DPNIIRMIKMLKSSNNIYLIY
|.... |.|| ||...| ..   |.. | |..   |  ..   . .  |.||........                   .|.|..|. . .. .|||...
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EFLQGRNLKKLLNERHH-----------------LSEMEAV-----QIFQQICKGFQRLQAEK-IIKKNLNSHNVHIIEHQSENQQISYEVKLKHFFICK
|...| .|.. ...|..                 ..| .|.     ..| ||..|.. |  .. ||  ..   |. . . ..      |..|.  |.|.|
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-----NYYIKIIDFGISK

SSSSNSSSSRKF---------EQFLNEKF---HYV----APELLVN-SQADSTV--CDIFSAGVVLYEMLLGSLPFE--KYANNKEDLTEFYSN-----N
 . .|. .  ..         .| .. .     |     |||.| .  . .|.   |||.| ||.||||| | .||.  ..  .. . |..  |     .
KYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWI-NNAYRKQ

DIQDVIAQDIS-----------HLSERIQLLLN----RMLVVEQDERITWEEIFEIVAQ
 .|. ....|.           |.|.  . ..|    .||.. ...|||.|.|..    
LYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 26436.AA S_TKc 8-278 21 8.8e-28 99.53 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-278
Range on HMM: 1-231/231
Sequence Identity: 21% (63 aa)

YILLEHICQGTFGEIHKGRNLISKEAVAVKTIQLEQFLNDSVLRDMIINEIQALKKLEDPNIIRMIKMLKSSNNIYLIYEFLQG--RNLKKLLNERHH--
| .|..| .|.||. .|.|.  ... ||.| |            ..|..||| |||   |||.... .  . ...|.. |.. |   .|.... .| .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LSEMEAVQIFQQICKGFQRLQAEKIIKKNLNSHNVHIIEHQSENQQISYEVKLKHFFICKSSSSNSSSSRKFEQFLNEKF----HYVAPELLVNSQ
    ..| .|  ...|||.. . .   .||   |   |. . |          ..|.  | ...                   |    .|.|||.|   .
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----------HIKICDFGLARQL---------------TTFCGTPWYMAPEVL---G

ADSTVCDIFSAGVVLYEMLLGSLPFEKYANNKEDLTEFYSNNDIQDVIAQDISHLSERIQLLLNRMLVVEQDERITWEEIFE----------I
 .   ||. | |..||||| |  ||.                  .... . |   |.    .....|... ..|.|  |...          .
YGKCKCDWWSCGCILYEMLCGYPPFP-----------------QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 26436.AA CAMKL 8-119 24 2.8e-26 80.76 In-house 1-139 (297) Show / Hide 
Range on Protein: 8-119
Range on HMM: 1-139/297
Sequence Identity: 24% (34 aa)

YILLEHICQGTFGEIHKGRN-LISKEAVAVKTIQLEQFLNDSVLRDM-----------IINEIQALKKLE---DPNIIRMIKMLKSSNN------IYLIY
|.... . .|.||.   ... .. .| ||.| |  .   || . ...           |  ||| .|.|     ||||..  ..  ...      |||. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFLQGRN--LKKLLNERHH----LSEMEAVQIFQQICKG
|  .| .  |   . .. |    ..| || ..|.||. .
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSA
Kinase 26436.AA CAMK 13-119 15 8.1e-23 69.72 In-house 1-191 (425) Show / Hide 
Range on Protein: 13-119
Range on HMM: 1-191/425
Sequence Identity: 15% (29 aa)

HICQGTFGEIHKGRNLISK------------EAVAVKTIQLEQFLND------------------------SVLRDMIINEIQALKK-------LEDPNI
 . .|.||. .....  ..            . ||.| |  ..  ..                         . |... .||. .||       |  |||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRMIKMLKSSNN-------------------IYLIY---EFLQGR----NLKKLLNERHH---------------LSEMEAVQIFQQICKG
|... .  ....                   .|..    |. .|      |   . |. .               ..| || ..|.||| .
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSA
Kinase 26436.AA Ciliate-E2 184-277 28 7.9e-20 64.73 In-house 252-361 (365) Show / Hide 
Range on Protein: 184-277
Range on HMM: 252-361/365
Sequence Identity: 28% (33 aa)

HYVAPELLVN--------SQADSTVCDIFSAGVVLYEMLLGSLPFEKYANNKEDLTEFYSNNDIQDVIAQDI-------SHLSERIQLLLNR----MLVV
.|.||| | .        ..  .. |||.|.||.||||| | .||  . ..|.   .| ... . |    .|        ..|.  . |...    ||..
GYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--QQQIKQCKIDFPCPEWQKD-TQ-CIQCKWKSWKKWSQECKDLIKKFGKRMLQK

EQDERIT-WEEIFE
....||| ||.|..
DPEKRITGWEQILN
Kinase 26436.AA Pkinase 8-119 26 3.2e-18 65.49 Pfam 1-120 (293) Show / Hide 
Range on Protein: 8-119
Range on HMM: 1-120/293
Sequence Identity: 26% (32 aa)

YILLEHICQGTFGEIHKGRNLISKEAVAVKTIQLEQFLNDSVLRDMIIN--EIQALKKLEDPNIIRMIKMLKSSNNIYLIYEFLQGR----NLKKLLN--
| ... | .|.||.  |...  . . ||||.| ..   ..|  .   ..  ||| .|.|  |||.|.. .  ....||.. |...|      |. ..   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

ERHHL--SEMEAVQIFQQICKG
..  .  || |.  .. ||..|
RHGCFYFSEWECKFYMYQILRG
Kinase 26436.AA Ciliate-E2 8-129 19 5.6e-18 58.29 In-house 1-183 (365) Show / Hide 
Range on Protein: 8-129
Range on HMM: 1-183/365
Sequence Identity: 19% (35 aa)

YILLEHICQGTFGEIHKGRNLISKE------------------AVAVKTIQLEQF-LNDSVLRDMIINEIQ-------------ALKKLEDPNIIRMIKM
|.... |.||.|| . |...   ..                   |..| . ....  |.     ..|....              |..|  ||||.|.  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LK--SSNNIYLIYEFLQGRNLKKLLNER-----------HHLSEMEAVQIFQQICK---------------GFQRLQAEK-II
 .  . |||||. |..|| .|.......           . ..| |. .|..||..               ... |  .. ||
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNII
Kinase 26436.AA MARK 8-119 29 4.1e-17 52.65 In-house 1-116 (262) Show / Hide 
Range on Protein: 8-119
Range on HMM: 1-116/262
Sequence Identity: 29% (34 aa)

YILLEHICQGTFGEIHKGRNLISKEAVAVKTIQLEQFLNDSVLRDMIINEIQALKKLEDPNIIRMIKMLK--SSNN-IYLIYEFLQGRNLKKLLNER--H
| .|  | .|....  ..... ... ||.|... .. |||   . ..  ||. .|||. ||||.. ..     ... |||| |   | .|   . ..  .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFK-LNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

HLSEMEAVQIFQQICKG
.|.| || .||.||. .
RLHEEEARRIFRQIVSA
Kinase 26436.AA CAMK 184-275 20 5.3e-15 44.08 In-house 284-419 (425) Show / Hide 
Range on Protein: 184-275
Range on HMM: 284-419/425
Sequence Identity: 20% (28 aa)

HYVA-PELLVN-------------SQADSTVCDIFSAGVVLYEMLLGSLPFEKYANNKE--------DLTEFYSNNDIQDV--IAQDISH----------
.|.| ||.|                . ..  ||. |.||.|| || | .||.   .| .        .. | . .    .   .   .|.          
EYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWW

----------LSERIQLLLNRMLVVEQDERITWEEI
          .|.  . |...||.|. ..|.| |..
DDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQC
Kinase 26436.AA Ciliate-E2c 16-129 24 1.8e-14 47.24 In-house 9-137 (310) Show / Hide 
Range on Protein: 16-129
Range on HMM: 9-137/310
Sequence Identity: 24% (32 aa)

QGTFGEIHKG------RNLISK----EAVAVKTIQLEQF----LNDSVLRDMIINEIQALKKLEDPNIIRMIKMLKSSNNIYLIYEFLQGRNLKKLLNER
.|..|   |.      .| | .       |.| ..|  .     |..     ||.||. .|..  |.||...   . ...|||| |.  | .|.... ..
SGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMNHPHIIKFYDAKQTDKHIYLIMEYCNGGTLEQYIYHK

HHLSEMEAVQIFQQICKGFQRLQAE-KII
  ..| . .  | ||  .|. |  | .|.
PKPNEKQCLYYFSQIISAFKYLHKEKNIF
Kinase 26436.AA Ciliate-E2b 8-129 24 1.2e-13 38.05 In-house 1-124 (272) Show / Hide 
Range on Protein: 8-129
Range on HMM: 1-124/272
Sequence Identity: 24% (30 aa)

YILLEHICQGTFGEIHKGRN-LISKEAVAVKTIQLEQFLNDSVLRDMIINEIQALKKLEDPNIIRMIKMLKSSNNIYLIYEFLQGRNLKKLLNERH--HL
 |      .| || .  ..|   .|.  | | |.  | .  . . . ...|.. |.|.. |.|.. |.  |.....|.. || .|  |  .. |     |
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQN-MEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLL

SEMEAVQIFQQICKGFQRLQAEKII
|. ..  .. .||.... |.  .||
STYDSQFYIASICLCLEYLHNQNII
Kinase 26436.AA Ciliate-E2a 8-129 23 3.7e-13 35.12 In-house 1-124 (275) Show / Hide 
Range on Protein: 8-129
Range on HMM: 1-124/275
Sequence Identity: 23% (29 aa)

YILLEHICQGTFGEIHKGRNLISKEAVAVKTIQLEQFLNDSVLRDMIINEIQALKKLEDPNIIRMIKMLKSSNNIYLIYEFLQGRNLKKLLNERHHLSEM
| ..  | .|.||   . . .. ..  |.| .    . ..   .  ..|||. ...|  ||||...   .. ||.||..|...|. |.. ... . . | 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--EAVQIFQQIC-KGFQRLQAEKII
  |. .| ||.  .|.. ..  .|.
IQEICDIMQQLLWQGLHYMHQRNIM
Kinase 26436.AA CAMKL 184-275 28 5.3e-13 37.69 In-house 198-291 (297) Show / Hide 
Range on Protein: 184-275
Range on HMM: 198-291/297
Sequence Identity: 28% (28 aa)

HYVAPELLVN--SQADSTVCDIFSAGVVLYEMLLGSLPFEKYAN---NKEDLTEFYSNNDIQDVIAQDISHLSERIQLLLNRMLVVEQDERITWEEI
.| |||..     . |    || |.||.|| |. | |||.   .   .|..  ..|  . ..       .|.| . . |. .||.|  ..|.| ..|
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQI
Kinase 26436.AA Pkinase 184-279 20 2.4e-12 44.75 Pfam 176-293 (293) Show / Hide 
Range on Protein: 184-279
Range on HMM: 176-293/293
Sequence Identity: 20% (25 aa)

HYVAPELLVNSQADSTVCDIFSAGVVLYEMLLGSLPFEKYAN----NKEDLTEFYSNNDIQDVIAQDISHLS-------------------ERIQLLLNR
.|.|||..  .| ... .|..|.|..|||||.| .||         |  |  . . ..   ..  .     |                   |  . ....
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFP--GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKW

MLVVEQDERITWEEIFEI--V
.| .   .|.|.|.|..   .
CLCKDPKKRPTAEQILQHPWF
Kinase 26436.AA Ciliate-E2b 184-279 19 1.1e-11 31.89 In-house 170-272 (272) Show / Hide 
Range on Protein: 184-279
Range on HMM: 170-272/272
Sequence Identity: 19% (21 aa)

HYVAPELLV----NSQADSTVCDIFSAGVVLYEMLLGSLPFEKYANNKEDLTEFYSNN--DIQDVIAQDISHLSERIQ------LLLNRMLVVEQDERIT
|| |||..       .  ..  ||.| |..|||.. | .|.   . . . . ..  ..  .|     |  |......        .|..| .|    .. 
HYMAPEIIQSLQPGGKGYTYKVDIWSVGICLYEFMCGYVPWAEDVQDPYEIYQEIIKKYDEI-----QFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYS

WEEIFEIV
|.. ..  
WLKSHPWF
Kinase 26436.AA Ciliate-E2a 184-221 41 7.3e-11 28.23 In-house 175-217 (275) Show / Hide 
Range on Protein: 184-221
Range on HMM: 175-217/275
Sequence Identity: 41% (18 aa)

HYVAPELLVNSQ--AD---STVCDIFSAGVVLYEMLLGSLPFE
.|||||.| | .   .   .| ||..|.||..| .| |..||.
GYVAPEVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFK
Kinase 26436.AA TyrKc 8-279 18 4.2e-10 -59.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-279
Range on HMM: 1-280/280
Sequence Identity: 18% (56 aa)

YILLEHICQGTFGEIHKGRNLISKEAVAVKTIQLEQFLNDSVLRDMIINEIQALKKL--EDPNIIRMIKMLKSS-------NNIYLIYEFLQGRNLKKLL
  |.. .  | |||..||.     . ||||... .        | ....|.. ..||  . |||.|..    ..         .... |.  . .||. |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

-NERHHLSEMEAVQIFQQICKGFQRLQAEKIIKKNLNSHNVHIIEHQSENQQISYEVKLKHFFICKSSSSN----SSSSRKFEQF-LNEK----FHYVAP
 . |..|.  . ...  ||..| . |   ..|   |   |. . | .         ||   |  ..   .      |.. .  .   ..|        ||
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

ELLVNSQADSTVCDIFSAGVVLYEMLLGSLPFEKYAN------NKEDLTEFYSNNDIQDVIAQDISH-----LSERIQLLLNRMLVVEQDERITWEEIFE
| . |    .|  |..| ||...|..  ..  . | .      . ... |.  . .  .  . |         .. .  .  .    . ..| | .|| |
ECI-NYGKFTTKSDVWSFGVCMWEIF--TYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

IV
. 
CF
Kinase 26436.AA Pkinase_Tyr 8-119 24 3.2e-09 31.84 Pfam 1-123 (270) Show / Hide 
Range on Protein: 8-119
Range on HMM: 1-123/270
Sequence Identity: 24% (31 aa)

YILLEHICQGTFGEIHKGRNL----ISKEAVAVKTIQLEQFLNDSVL--RDMIINEIQALKKL-EDPNIIRMIKMLK-SSNN--IYLIYEFLQGRNLKKL
 .... . .| |||..||.        |  ||||..  |    ..    |.. ..|.. .|.|   |||.|..      .    ||.. |. .. .|.. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LNE----RHHLSEMEAVQIFQQICKG
| .    ...|.  . .|. .||.||
LRKHREDKQPLTMKDLLQMCWQIAKG
Kinase 26436.AA Ciliate-E2c 185-279 25 8.4e-09 27.08 In-house 184-310 (310) Show / Hide 
Range on Protein: 185-279
Range on HMM: 184-310/310
Sequence Identity: 25% (32 aa)

YVAPELLVNSQADSTVCDIFSAGVVLYEMLLGSLPFE---------------KYANN-KEDLTEFYSN-----------NDIQDVIAQDIS---HLSERI
| ||. |  .... .  || |.||.||.||   ||.|                .  |  . | .  ..             |. .|    .    .|. .
YMAPQILEGKNYYTEKSDIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEV

QLLLNRMLVVEQDERITWEEIF--EIV
. |...||.|.   || |.|||  |. 
KQLIHKMLQVDEEKRIDWDEIFNHECI
Kinase 26436.AA MARK 202-228 50 3e-06 16.69 In-house 188-215 (262) Show / Hide 
Range on Protein: 202-228
Range on HMM: 188-215/262
Sequence Identity: 50% (14 aa)

DIFSAGVVLYEMLLGSLPFE-KYANNKE
|| | ||||| |. |..||. . ...||
DIWSLGVVLYFMVCGYFPFDGDTQDYKE
Kinase 26436.AA MARK 248-275 42 0.001415 7.75 In-house 229-256 (262) Show / Hide 
Range on Protein: 248-275
Range on HMM: 229-256/262
Sequence Identity: 42% (12 aa)

SHLSERIQLLLNRMLVVEQDERITWEEI
.|.|  .. |..|.|.|  .||.| |||
CHVSKECRNLIQRLLTVNPEERPTIEEI
Kinase 26436.AA Ciliate-E2a 741-748 62 0.084164 1.11 In-house 268-275 (275) Show / Hide 
Range on Protein: 741-748
Range on HMM: 268-275/275
Sequence Identity: 62% (5 aa)

DVLNHPYF
. ||||.|
QALNHPWF
Kinase 26436.AA Ciliate-E2 741-748 62 0.155906 1.01 In-house 358-365 (365) Show / Hide 
Range on Protein: 741-748
Range on HMM: 358-365/365
Sequence Identity: 62% (5 aa)

DVLNHPYF
..||||.|
QILNHPWF
Kinase 26436.AA Ciliate-E2-Unclassified 727-748 33 0.162538 1.05 In-house 329-352 (352) Show / Hide 
Range on Protein: 727-748
Range on HMM: 329-352/352
Sequence Identity: 33% (8 aa)

IDIMYNKFLGKK--RLDVLNHPYF
.  | .| ..|.    ..||||.|
LQKMLKKNPNKRITFEQILNHPWF
Kinase 26436.AA Pkinase 737-748 46 6.523543 0.77 Pfam 279-293 (293) Show / Hide 
Range on Protein: 737-748
Range on HMM: 279-293/293
Sequence Identity: 46% (7 aa)

KKRL---DVLNHPYF
|||.   ..|.||.|
KKRPTAEQILQHPWF