Gene 15684 (Tetrahymena)

15684

Species: Tetrahymena
Alias: 584, TTHERM_00295740, 3692.m00147, PreTt15684, 27.m00344, 15684
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
15684.AA Protein None 794 None Fasta, JSON
15684.kin_dom Protein Kinase Domain None 256 None Fasta, JSON
15684.NA RNA None 2385 None Fasta, JSON

Protein domain

Protein domains of 15684.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15684.AA STE11-Unclassified 156-411 46 5.4e-169 567.71 In-house 4-308 (308) Show / Hide 
Range on Protein: 156-411
Range on HMM: 4-308/308
Sequence Identity: 46% (143 aa)

DKILGKGTFGTVVLGHNKNTGEIVAVKLIET------QYDRKQK-YKSIIDEVKILKQMRHKNIVRYYGIQEHKAKDHIGIVCEYVSGGSLWRLIQKFGK
....|||.||.|....|.||||..||| ||.      |.|.... ..||..|.|.|||..|||||.|||...||..|.|.|..||..|||.|....|.|.
GEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNKYGC

FSEPLIRKYTTDILYGLQYLHYHGITHRDIKGANILVDSDGVCKLADFGLAK---------------------SISQEIDE--GQLKLPQGTPN---WMA
|.|..|.|||..||.||.|||.|||.||||||||||.|.||.|||.|||.||                     .|.|.|..  ...|..||||.   |||
FDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPFWMA

PEVCR---S-GTCRFSDIWSLGCTVYEMITGKPPFSNFLA---ETIILRVGLLKQPPQFLENLQ---------ISEKLSDFLLHCFQIKPEERWNVDQLL
|||..   . |.||.||||||||||.||.|||.|.||. .   . .|. ... .|.||..|.|.         ||....||| .||||.|..|....|||
PEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTANQLL

QHPFI
|||||
QHPFI
Kinase 15684.AA STE11 153-411 44 5.2e-151 507.98 In-house 1-303 (303) Show / Hide 
Range on Protein: 153-411
Range on HMM: 1-303/303
Sequence Identity: 44% (136 aa)

KTDDKILGKGTFGTVVLGHNKNTGEIVAVKLIETQYDRK------QKYKS------IIDEVKILKQMRHKNIVRYYGIQEHK-AKDHIGIVCEYVSGGSL
 .  .|.|||.|||| ...|..|||..||| ||.| ...      ..|.|      | .|.|..|...|||||||||.. |. ..||. | .||..||||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

WRLIQ-KFGK--FSEPLIRKYTTDILYGLQYLHYHGITHRDIKGANILVDSDGV-CKLADFGLAKSISQEIDEGQLKLP--------QGTPN--------
..... |.|.  |.|..|||||..||.||||||.||| ||||||||||.||||. ||||||| ||...... ... . .        .|||.        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

WMAPEVCRSGT----CRFSDIWSLGCTVYEMITGKPPFSNFLA--ETIILRVGLL-KQPPQFLENLQ-IS---EKLSDFLLHCFQIKPEERWNVDQLLQH
||||||.. ..    .| .|||||||||.||.|||||..|. .   ... ..|   |..|.. |... ||   |.. |||.|||.. |..|....|||||
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

PFI
|||
PFI
Kinase 15684.AA STE 153-411 29 1.6e-105 356.89 In-house 1-359 (359) Show / Hide 
Range on Protein: 153-411
Range on HMM: 1-359/359
Sequence Identity: 29% (106 aa)

KTDDKILGKGTFGTVVLGHNKN---------------TGEIVAVKLIETQYDRK---------------QKYKSIIDEVKILKQMR--HKNIVRYYGIQE
 .. ...|||.||||... |..               ||||.|.| .. . ...               .. ..|. |.||.|...  |.|||.|||  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----HKAKDHIGIVCEYVSGGSLWRLIQ-KF-------------GKFSEPLIRKYTTDILYG-LQYLHYHGITHRDIKGANILVDSDGVCKLADFGLAK
     ||..|.. |. ||..||||  .|. |.             ..|.|..|.... .|| | |.||| |.| |||||.||||.     .||.|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

SISQEIDEG--------------QLKLPQGTPNWMAPEVCR-------SGTCRFSDIWSLGCTVYEMITGKPPFSNFLAETIILRVGLL-----------
.........              . .   ||| |||||| .       .|  . .||||||||. ||.|||||....     ...               
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---KQPPQFLENLQ-----------------ISEKLSDFLLHCFQIKPEERWNVDQLLQ--HPFI
   ..||.. ..|.                  |... ||. .|.|. |..|....|||.  ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 15684.AA S_TKc 153-411 33 3.3e-96 326.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 153-411
Range on HMM: 1-231/231
Sequence Identity: 33% (92 aa)

KTDDKILGKGTFGTVVLGHNKNTGEIVAVKLIETQYDRKQKYKSIIDEVKILKQMRHKNIVRYYGIQEHKAKDHIGIVCEYVSG--GSLWRLIQKFGK--
 .  ...|||.||.| ....|.||.|||.| |          ..|. |..|||. .|.|||..|.. ..   ||. .| ||..|  |.| ..|.| |.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FSEPLIRKYTTDILYGLQYLHYHGITHRDIKGANILVDSDGVCKLADFGLAKSISQEIDEGQLKLPQGTPNWMAPEVCRSGTCRF--SDIWSLGCT
    |.|  .|.|.  |. .|.|.| ||| |||.| .|||.|.  . |..|||||. .         .   |||..|||||.      .  .|.||.||.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

VYEMITGKPPFSNFLAETIILRVGLLKQPPQFLENLQISEKLSDFLLHCFQIKPEERWNVDQLLQ-------HPFI
.|||..|.|||.    .  .... .             |. . ||. .|.|  ||.|. . ..||       ||..
LYEMLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15684.AA Pkinase 153-411 34 9.8e-82 282.64 Pfam 1-293 (293) Show / Hide 
Range on Protein: 153-411
Range on HMM: 1-293/293
Sequence Identity: 34% (102 aa)

KTDDKILGKGTFGTVVLGHNKNTGEIVAVKLIETQYDRKQKYKSIID--EVKILKQMRHKNIVRYYGIQEHKAKDHIGIVCEYVSGG----SLWRLIQ--
 .  ...|.|.||.| ..|.|.||.||||| |. . ....| .. .   |..|.| ..|.||||.|.. |   |||| .| ||. ||    .|...|.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

KFGKF--SEPLIRKYTTDILYGLQYLHYHGITHRDIKGANILVDSDGVC----KLADFGLAKSISQEIDEGQLKLPQGTPNWMAPEVCR--SGTCRFSDI
. |.|  ||  ...| . || ||.|.| .|| |||.| .|||.|..|..    |..|||||| .. .   . .. . |||..|||||.|  ..  . .|.
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGCTVYEMITGKPPFSNF------LAETIILRVGLLKQPPQFLENLQIS-----------------EKLSDFLLHCFQIKPEERWNVDQLLQHPFI
||.||..|||..|.|||..           .| |..  . . .. .   ||                 | . ||.  |.. .|..|.. .|.||||..
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 15684.AA ULK 153-411 30 8.8e-72 244.78 In-house 1-329 (329) Show / Hide 
Range on Protein: 153-411
Range on HMM: 1-329/329
Sequence Identity: 30% (100 aa)

KTDDKILGKGTFGTVVLGHNKNT----GEIVAVKLIETQYDRKQKYK--------SIIDEVKILKQMR----HKN----IVRYYGIQEHKAKDHIGIVCE
   ...||||.||.|  | ||.|    .|.||.| |. |. .....         ... |.||.|..     |||    ||..| ..| .  ..| |. |
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YVSGGSLWRLIQKFGK----------FSEPLIRKYTTDILYGLQYLHYHGITHRDIKGANILVDSD------------GVCKLADFGLAKSISQE-IDEG
|  || |  .|.| .|          .||. ....  .|| |...|| |.| ||||| .|||.. .            ||.|.||||.||... .  .. 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

QLKLPQ------GTPNWMAPEVCRSG-----TCRF-SDIWSLGCTVYEMITGKPPFSNFLAETII------LRVG-------LLKQPPQFL---ENLQIS
...         |||  |||..  .       . . .|||||||  |||..|||||..  ... .      |.           |||.||    .. |||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

EKLSDFLLHCFQIKPEERWNVDQLLQHPFI
... |..  ..|.....| . ..|..||..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 15684.AA CAMK 158-411 21 1.8e-71 229.35 In-house 1-425 (425) Show / Hide 
Range on Protein: 158-411
Range on HMM: 1-425/425
Sequence Identity: 21% (90 aa)

ILGKGTFGTVVLGHNKNTG------------EIVAVKLIET----------------QYDRKQKY----------KSIIDEVKILKQ-------MRHKNI
.||.|.||.| |. .|||.            . ||.| |..                  ..|.|           |..  |..|.|.       ..|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRYYGIQEHKA-----------------KDHIGIVC---EYVSGG----SLWRLIQKF---------------GKFSEPLIRKYTTDILYGLQYLHYHGI
.. | . | .                  ..|. .|    ||.|||     |   |..                |.|.|   |.|   |. ...|.| |.|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

THRDIKGANILVDSD-----------------GVCKLADFGLAKSISQEIDEG---------------------QLKLPQGTPNWMA-PEVCR-------
 |||.|  |||.|..                 .  |..|||.|. . .  ..                       .| . |||  || ||| .       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------SGTCRFSDIWSLGCTVYEMITGKPPFSNF-------------LAETIILRVGLLK-Q-PPQFLENLQ----------ISEK--------LSD
         .  . .|.||.|.  | | .|.|||                  . .  ..   | . || .. ..           ||.           |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FLLHCFQIKPEERWNVDQLLQHPFI
.. .. |  ||.|....| |.||..
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 15684.AA ULK 153-411 29 4.5e-70 239.1 In-house 1-324 (324) Show / Hide 
Range on Protein: 153-411
Range on HMM: 1-324/324
Sequence Identity: 29% (96 aa)

KTDDKILGKGTFG-TVVLGHNKNT---GEIVAVKLIETQYDRKQKYK--------SIIDEVKILKQMR---HKN--IVRYYGIQEHKAKDHIGIVCEYVS
   ...||||.|| .|  | ||.|   ...||.| |. .. .|.|..        ... |..|.|..    |.|  ||..| ..| .  ..| |. ||  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGSLWRLIQKFGK---------FSEPLIRKYTTDILYGLQYLHYHGITHRDIKGANILVDSD------------GVCKLADFGLAKSISQEIDEGQLK--
|| |  .|.| .|         .||. ....  .|. |...|| |.| ||||| .|||.  .            ||.|.||||.||..  .  | |.   
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

-----LPQGTPNWMAPEVCRSG-----TCRF-SDIWSLGCTVYEMITGKPPFSNFLAETIIL-RVGLLK-----------QPPQFL---ENLQISEKLSD
     .  |||  |||..  .       . . .|||||||  |||..||.||..  ... .|    |..           || ||    .. .||... |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

FLLHCFQIKPEERWNVDQLLQHPFI
..  ..|.....| . .....||..
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 15684.AA Dicty2 156-354 43 2.5e-69 236.63 In-house 5-210 (264) Show / Hide 
Range on Protein: 156-354
Range on HMM: 5-210/264
Sequence Identity: 43% (91 aa)

DKILGKGTFGTVVLGHNKNTGEIVAVKLIE----TQYDRKQKYKSIIDEVKILKQMRHKNIVRYYGIQEHKAKDHIGIVCEYVSGGSLWRLIQKFGKFSE
| ..||| ||||  | .. ||. || |.|.    .    .   .||. |...||  .| |||.|..  |   ..|. |. ||. .|||   | |||.|.|
DEKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLNHHNIVKYIEHIE--TENHLYIILEYIENGSLSKIIKKFGCFPE

PLIRKYTTDILYGLQYLHYHGITHRDIKGANILVDSDGV---CKLADFGLAKSISQEIDEGQLKLPQ-GTPNWMAPEVCR-SG--TCRFSDIWSLGCTVY
.|.  |   .| || |||  |. |||||.||||.  .|.    |||||| |  |.   .. ....   ||| ||||||   ||   |  .||||||||. 
SLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFGVATHID--YSDDDSRYTVVGTPYWMAPEVIQMSGNHCCTACDIWSLGCTII

EMITGKPPFS
|. || || .
ELLTGNPPYW
Kinase 15684.AA STE20 154-411 34 2.3e-66 226.82 In-house 2-288 (288) Show / Hide 
Range on Protein: 154-411
Range on HMM: 2-288/288
Sequence Identity: 34% (98 aa)

TDDKILGKGTFGTVVLGHNKNTGEI----VAVKLIETQYD---RKQKYKSIIDEVKILKQMRHKNIVRYYGIQEHKAK--DHIGIVCEYVSGGSLWRLIQ
.. . .|.|..|.| ....| |||.    ||.| ..   .   . .. ..|. |. |.|| .|.|||.|||    . .  |.. || || .||||  ...
ELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ-DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---KFGK------FSEPLIRKYTTDILYGLQYLHYHGITHRDIKGANILVDSDGVCKLADFGLAKSISQE---IDEGQLKLPQGTPNWMAPEVCRS----
   | ||      ..|. |   . ..| ||.||| ..| |||||..|||...|| .||||||.. .....    . .. .   ||| |||||| .     
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-GTCRF-SDIWSLGCTVYEMITGKPPFSNFLAETIILRVG-LLKQPPQFLE--NLQISEKLSDFLLHCFQIKPEERWNVDQLLQHPFI
 .   . .|||||| |  ||..|.||.... .   ....    ..|| . .    . | .. ||. .| |. ||.|. ..|||.||||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 15684.AA MEKK15 154-411 40 6.1e-66 225.38 In-house 2-264 (264) Show / Hide 
Range on Protein: 154-411
Range on HMM: 2-264/264
Sequence Identity: 40% (109 aa)

TDDKILGKGTFGTVVLGHNKNTGEIVAVKLIE----TQYDRKQKYKSIIDEVKILKQMRHKNIVRYYGIQEHKAKDHIGIVCEYVSGGSLWRLIQKFGKF
.  .||||| .|||  |   ||| ..||| .|     .   ||.|. . .||..|| ..||||| | |.  .     . |  ..| |||.  .| .||  
KKGNILGKGAYGTVYCGLT-NTGQLIAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLE--DNVVNIFMQFVPGGSISSIINRFGPL

SEPLIRKYTTDILYGLQYLHYHGITHRDIKGANILVDSDGVCKLADFGLAKSISQE-IDEGQ---LKLPQGTPNWMAPEVCR-SGTCRFSDIWSLGCTVY
 |    |||  || | ||||   . ||||||.|... . |. || ||| || .. . |.  .   ||  .||| ||||||   .|  | |||||.||||.
DEMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIMETGYGRKSDIWSIGCTVF

EMITGKPPFSNFLAETIILRVGLLKQPPQFLENLQISEKLSDFLLHCFQIKPEERWNVDQLLQHPFI
|| |.|||. .      .  .|  ..|   |   . ||.  .|   |     .||    |||.||||
EMATRKPPWADMDRMAAMFYIGAHRDPMPQLP-VKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase 15684.AA Ciliate-E2 157-411 21 9.6e-64 217.69 In-house 5-365 (365) Show / Hide 
Range on Protein: 157-411
Range on HMM: 5-365/365
Sequence Identity: 21% (82 aa)

KILGKGTFGTVVLGHNKNTGEIVAVKLIETQY----------D---------RKQKYKSIIDEVKILKQMR----------------HKNIVRYYGIQEH
|..|.|.||.| .. ...... .| |.|. |.          .         .|.. ..|  | .|.....                |.||...|   . 
KKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQE

KAKDHIGIVCEYVSGGSLWRLIQKF-----------GKFSEPLIRKYTTDILY---------------GLQYLHYHG-ITHRDIKGANILVDSDGVCKLA
| ...| .| ||..||.|. .|...           ..|.|  |..... ||.               .|.|||  . | |||||  |||.     .|..
KDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKII

DFGLAKSISQEIDEGQ------LKLPQG------------------------TPNWMAPEVCRSGTC----------RFSDIWSLGCTVYEMITGKPPFS
||||.| .... ....      ...  .                        ||. ||||. ...              .||||||.. |||..||||| 
DFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-

NFLAETIILRVGLLKQPPQFL------------ENLQISEKLSDFLLH----CFQIKPEERWN-VDQLLQHPFI
      ..   . .. |...             .....|..  |..      ..| .||.| .  .|.|.||..
-----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 15684.AA Pkinase_Tyr 156-355 33 1.1e-38 131.63 Pfam 4-218 (270) Show / Hide 
Range on Protein: 156-355
Range on HMM: 4-218/270
Sequence Identity: 33% (73 aa)

DKILGKGTFGTVVLGHNK----NTGEIVAVKLIETQYDRKQ-KYKSIIDEVKILKQM-RHKNIVRYYGIQE-HKA-KDHIGIVCEYVSGGSLWRLIQK--
.| ||.| ||.|..|. |    ||.  |||| .  ... .| . .. . |.||.||. .|.||||.||.   ..  . .| || ||. .|.|    .|  
GKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYLRKHR

--FGKFSEPLIRKYTTDILYGLQYLHYHGITHRDIKGANILVDSDGVCKLADFGLAKSI---SQE-IDEGQLKLPQGTPNWMAPEVCRSGTCRF-SDIWS
   .... . . .. ..|  |..||. ... |||.   |.||....|.| .|||||. |   ..     |  |||     |||||. . | .   ||.||
EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLP---IKWMAPECINYGKFTTKSDVWS

LGCTVYEMIT-GKPP-FSN
 | . .|..| |. | . .
FGVLMWEIFTYGEQPTYPG
Kinase 15684.AA TyrKc 153-411 25 2.8e-29 104.52 SMART 1-280 (280) Show / Hide 
Range on Protein: 153-411
Range on HMM: 1-280/280
Sequence Identity: 25% (74 aa)

KTDDKILGKGTFGTVVLGHNKNTGEIVAVKLIETQYDRKQKYKSIIDEVKILKQM--RHKNIVRYYGIQEHKAK-----DHIGIVCEYVSGGSLWRLIQK
 | .|.|| | ||.|..|. |   . |||| .          . ...| .|...   .|.|||| ||.  ..       . . || ||...|.|   ..|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

FGK-FSEPLIRKYTTDILYGLQYLHYHGITHRDIKGANILVDSDGVCKLADFGLAKSISQE--------IDEG----QLK--LPQGTPNWMAPEVCRSGT
 .. .. .   .. ..|  | .||| ... |||.   |.||......| .||||.. |  .                . |  ||     |||||. . |.
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI---RWMAPECINYGK

CRF-SDIWSLGCTVYEMIT-GKPPFSN-----FLAETIILRVGLLKQPPQFLENL-----QISEKLSDFLLHCFQIKPEERWNVDQLLQHPFI
. . ||.|| | . .|. | |..| ..       .. .| .|   . .||  ...       .... .  . | . .||.| .  ..  | ..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 15684.AA Dicty2 380-411 46 3.2e-08 24.92 In-house 233-264 (264) Show / Hide 
Range on Protein: 380-411
Range on HMM: 233-264/264
Sequence Identity: 46% (15 aa)

ISEKLSDFLLHCFQIKPEERWNVDQLLQHPFI
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ISPECKDFLMQCFCKDPNQRMTAKQLLHHPWI