Gene 7147 (Tetrahymena)

7147

Species: Tetrahymena
Alias: 3679.m00052, 674, 7147, PreTt07147, 46.m00202, TTHERM_00420220
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
7147.AA Protein None 854 None Fasta, JSON
7147.kin_dom Protein Kinase Domain None 251 None Fasta, JSON
7147.NA RNA None 2565 None Fasta, JSON

Protein domain

Protein domains of 7147.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 7147.AA STE11-Unclassified 122-372 41 2.7e-159 535.49 In-house 1-308 (308) Show / Hide 
Range on Protein: 122-372
Range on HMM: 1-308/308
Sequence Identity: 41% (128 aa)

YKKCELIDKGAYGKVYKGIDTITNQVVAIKYIEITGTF---EEVKKE-INSLKKEIVLLKKLNHQNIVKYYDFEISDDKSGVDIILEYVPNGSLRMALNK
..|.|.|.||..|.|||.....|....|.|.|||....   |...|| |.|..||...||.|||.|||.||..||........|..||.|.||....|||
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNK

QRCFDETKAAIYTKQVLEGLDYLHKNNIIHRDLKGANLLLDAEGRAKLTDFGTAKQIEFD--------------LRKSQVKEEDIAKMNKSLKGTPN---
..||||.....||||.||||.|||...|||||.||||.|.|..|..||||||.|||||||              ..|............||..|||.   
YGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPF

WMAPEVIE---RTGHTTSADIWSIGCIVIEMITGKPPYPGL----SAKEVFTKIASG-----------------------------GCLQTDPKKRLTTS
|||||||.    |||....||||.||.||||.|||.|....    ..........|.                             .|.|.|||||.|..
WMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTAN

QLLKTPFI
|||..|||
QLLQHPFI
Kinase 7147.AA STE11 122-372 39 4.4e-139 468.34 In-house 1-303 (303) Show / Hide 
Range on Protein: 122-372
Range on HMM: 1-303/303
Sequence Identity: 39% (120 aa)

YKKCELIDKGAYGKVYKGIDTITNQVVAIKYIEITGTF---EEVKKEINS------LKKEIVLLKKLNHQNIVKYYDFEISD-DKSGVDIILEYVPNGSL
..|.|.|.|||.|.|||.... |....|.|.||| ..    |. .||..|      ...|| |.|.|||.|||.||.....| ....| |..||.|.|||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

RMALN-KQRC--FDETKAAIYTKQVLEGLDYLHKNNIIHRDLKGANLLLDAEGR-AKLTDFGTAKQIEFDLRKSQVKEEDIAKMNKSLKGTPN-------
.. |. |. .  |||.   .||||.|||| |||...|||||.||||.|||..|   ||.|||.||... ...... ...... ..||..|||.       
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQN-HCKSMTGTPYNSMMGTP

-WMAPEVIERTG---HTTSADIWSIGCIVIEMITGKPPYPGL---SAKEVFTKIAS-G------------------------GCLQTDPKKRLTTSQLLK
 ||||||| ..|   ....|||||.||.||||.|||||....   .. . |  ... .                         |.. ||||| | .|||.
MWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQ

TPFI
.|||
HPFI
Kinase 7147.AA STE 122-372 28 4.6e-97 328.78 In-house 1-359 (359) Show / Hide 
Range on Protein: 122-372
Range on HMM: 1-359/359
Sequence Identity: 28% (105 aa)

YKKCELIDKGAYGKVYKGIDT------ITNQV---------VAIKYIEITGT-FEEVK------------KEINSLKKEIVLLKKLN--HQNIVKYYDFE
... | | |||.|.|||...        |..|         .||| ...     .. .            .|.....||| ..||.|  |.||||||. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

ISDD-----KSGVDIILEYVPNGSLRMALN-KQRCFD-------------ETKAAIYTKQVLEG-LDYLHKNNIIHRDLKGANLLLDAEGRAKLTDFGTA
. ..     .. . |..||...|||.  .. |  |..             |.  |....|.|.| |.|||...|||||.|.|| ||     .||.|||..
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

KQIEFDLRKSQVKE-------EDIAKMNKSLKGTPNWMAPEVIER------TGHTTSADIWSIGCIVIEMITGKPPYPGLSAKEVFTKIASG--------
.|.. .....   .       |......... ||| |||||||..       |..|..||||.|| .|||.|||||.  ..  ..   |. .        
GQLTDSMANI-Q-SNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE

--------------------------------------------GCLQTDPKKRLTTSQLLK--TPFI
                                             ||| ||.|| |.|||||   |||
QLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 7147.AA S_TKc 122-372 33 9.7e-85 288.74 SMART 1-231 (231) Show / Hide 
Range on Protein: 122-372
Range on HMM: 1-231/231
Sequence Identity: 33% (93 aa)

YKKCELIDKGAYGKVYKGIDTITNQVVAIKYIEITGTFEEVKKEINSLKKEIVLLKKLNHQNIVKYYDFEISDDKSGVDIILEYVPN--GSLRMALNKQR
|.. ..| |||.|||||.... |...|||| |             .....|| .||| .| ||||.||.  .   . . ...||...  |.|.  . |..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRG

C------FDETKAAIYTKQVLEGLDYLHKNNIIHRDLKGANLLLDAEGRAKLTDFGTAKQIEFDLRKSQVKEEDIAKMNKSLKGTPNWMAPEVIERTGHT
.      |.|  |. |..|....|.|.|...||||||| .|.|||   . |..||| |.|.                  ... |||..|||||.   |..
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------TTFCGTPWYMAPEVL---GYG

T-SADIWSIGCIVIEMITGKPPYPGLSAKEVFTKI----AS---GGCLQTDPKKRLTTSQLLK-------TPFI
. ..|.||.|||..||..|.||.|    ...| ||    |     .||| ||.||.|  ..|.        |..
KCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 7147.AA Pkinase 122-372 29 2.3e-79 274.76 Pfam 1-293 (293) Show / Hide 
Range on Protein: 122-372
Range on HMM: 1-293/293
Sequence Identity: 29% (91 aa)

YKKCELIDKGAYGKVYKGIDTITNQVVAIKYIEITGTFEEVKKEINSLKKEIVLLKKLNHQNIVKYYDFEISDDKSGVDIILEYVPNG----SLRMALN-
|.. . | .|..|.|||...  |...||.| |.  .. ......   |  || ..|.||| |||..||.  ..|.    ...||...|    .|   .  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIY--MVMEYCEGGLYVMDLFDYIST

-KQRCF--DETKAAIYTKQVLEGLDYLHKNNIIHRDLKGANLLLDAEGRA----KLTDFGTAKQIEFDLRKSQVKEEDIAKMNKSLKGTPNWMAPEVIE-
 ...||  .|  .  | .|.|.||.|.|...||||||| .|.|.| .|      |..||| |||..          .     .... |||..||||||  
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------Y-NNS-MTTFCGTPWYMAPEVIRG

RTGHTTSADIWSIGCIVIEMITGKPPYPGL------SAKEVFTKIAS--------------------------------------GGCLQTDPKKRLTTS
........|.||.|||..||..|.||.||       . .... .| .                                       .||. |||||.|  
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

QLLKTPFI
|.|. |..
QILQHPWF
Kinase 7147.AA Dicty2 122-335 45 5.1e-72 245.57 In-house 1-209 (264) Show / Hide 
Range on Protein: 122-335
Range on HMM: 1-209/264
Sequence Identity: 45% (102 aa)

YKKC-ELIDKGAYGKVYKGIDTITNQVVAIKYIEITGTFEEVKKE-INSLKKEIVLLKKLNHQNIVKYYDFEISDDKSGVDIILEYVPNGSLRMALNKQR
|.   | | ||| |.|||| .. | ..|||| |.|       ..| . |...|| ||||||| |||||.... . . .   |||||. ||||.  ..|  
YQIGDEKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLNHHNIVKYIEHIETENHL--YIILEYIENGSLSKIIKKFG

CFDETKAAIYTKQVLEGLDYLHKNNIIHRDLKGANLLLDAEGR---AKLTDFGTAKQI---EFDLRKSQVKEEDIAKMNKSLKGTPNWMAPEVIERTG--
|| |.   || .|||.|| ||| . .|||| |.||.|   ||    .||.|||.| .|   . |.| . |             ||| |||||||.  |  
CFPESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFGVATHIDYSDDDSRYTVV-------------GTPYWMAPEVIQMSGNH

HTTSADIWSIGCIVIEMITGKPPY
..|. |||| || .||. || |||
CCTACDIWSLGCTIIELLTGNPPY
Kinase 7147.AA Ciliate-E2-Unclassified 122-372 23 3.2e-64 219.65 In-house 1-352 (352) Show / Hide 
Range on Protein: 122-372
Range on HMM: 1-352/352
Sequence Identity: 23% (85 aa)

YKKCELIDKGAYGKVYKGIDTITNQVV-----AIKYIEIT-GTFEEVKKEINSLKKEIVLLK-----K---------LNHQNIVKYYDFEISDDKSGVDI
||. . | .|..||||| ..  ..  .     ..|....     .... ||.  .||.  .|     |         |||........|..  ||  . |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ILEYVPNGSLRMALNKQ-----------------RCFDETKAA-----IYTKQVLEGLDYLHKNN-IIHRDLKGANLLLDAEG---RAKLTDFGTAKQIE
..||...|.|.  ..|.                 ..|.| .|.      |..|.|.||.|||..| |||||.|  |.|.| .|   . |..||| .|...
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

FDLRKSQVKEED--------IAKMNKSLKGTPNWM----APEVIERTGHTTS----ADIWSIGCIVIEMITGKPPYPGLSAKE----------------V
 .   .. . ..        . .| ..  |||| |    ||||... .. .|    .|||| |.|  ||..|..|... . ..                .
QN---NNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQL

FTKIASG-----------------------------GCLQTDPKKRLTTSQLLKTPFI
. .|  .                              .|. .|.||.| .|.|. |..
YQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 7147.AA MEKK15 122-335 43 1.3e-63 217.65 In-house 1-207 (264) Show / Hide 
Range on Protein: 122-335
Range on HMM: 1-207/264
Sequence Identity: 43% (93 aa)

YKKCELIDKGAYGKVYKGIDTITNQVVAIKYIEI-TGTFEEVKKEINSLKKEIVLLKKLNHQNIVKYYDFEISDDKSGVDIILEYVPNGSLRMALNKQRC
.|| ... ||||| || |. | | |..|.| .|. .   |. |..   |. |. ||| | |.||| |    . |    |.| ...|| ||.   .|.   
WKKGNILGKGAYGTVYCGL-TNTGQLIAVKQVELDEIDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDNV--VNIFMQFVPGGSISSIINRFGP

FDETKAAIYTKQVLEGLDYLHKNNIIHRDLKGANLLLDAEGRAKLTDFGTAKQIEFD-LRKSQVKEEDIAKMNKSLKGTPNWMAPEVIERTGHTTSADIW
 ||.    ||||.|.|  ||| |...|||.||.|..| . |  || ||| || . .  . ...      . | ||..||| |||||||  ||.   .|||
LDEMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLCWQGINRTH------SDMLKSMRGTPYWMAPEVIMETGYGRKSDIW

SIGCIVIEMITGKPPY
|||| | || |.|||.
SIGCTVFEMATRKPPW
Kinase 7147.AA ULK 122-335 33 3e-62 213.12 In-house 1-252 (324) Show / Hide 
Range on Protein: 122-335
Range on HMM: 1-252/324
Sequence Identity: 33% (86 aa)

YKKCELIDKGAYG-KVYKGIDTIT---NQVVAIKYIEITGTFEEVKKE------INSLKKEIVLLKKLN---HQN--IVKYYDFEISDDKSGVDIILEYV
| . . . ||..| |||||.. .|   ||.||.| |.. . . . |.|      ...||.|| ..|||.   |.|  |||.||.  ...   . ||.|| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKK-MNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYC

PNGSLRMALNKQRC---------FDETKAAIYTKQVLEGLDYLHKNNIIHRDLKGANLLLDA------------EGRAKLTDFGTAKQIEF-----DLRK
. | |.  ..|..          . | .| .. || ..|. .|||.||||||.| .|.|.              .|..|..||| ||...      ....
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

SQVKEEDIAKMNKSLKGTPNWMAPEVIERTG----HTTS-ADIWSIGCIVIEMITGKPPY
..| |       | .||||  |||..... |    .... .||||.|||  ||..||.|.
TCVNE-------KRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPF
Kinase 7147.AA STE20 122-335 37 3.3e-62 212.97 In-house 1-227 (288) Show / Hide 
Range on Protein: 122-335
Range on HMM: 1-227/288
Sequence Identity: 37% (89 aa)

YKKCELIDKGAYGKVYKGIDTITNQV----VAIKYIEITGTFEEVKKEINSLKKEIVLLKKLNHQNIVKYYDFEISDDKSGVD---IILEYVPNGSLRMA
|.. | | .|.||||||.... |...    |||| ...    .|  .|.....|||. .|...|.||||||.  . ||.   |   |. ||   |||. .
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ-DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTC-DDELWIVMEYCGGGSLTDI

LN---KQRC------FDETKAAIYTKQVLEGLDYLHKNNIIHRDLKGANLLLDAEGRAKLTDFGTAKQIEFDLRKSQVKEEDIAK-MNKSLKGTPNWMAP
..   |  .      ..|   |  ...||.||||||.|.|||||.|..| ||. .|..||.||| . |..    |   . .   .   ... ||| ||||
MKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLT----KHG-R-D-TMQFKRNTFVGTPYWMAP

EVIER-----TGHTTSADIWSIGCIVIEMITGKPPY
|||..      |... .|||| |   |||..|.|||
EVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPY
Kinase 7147.AA ULK 122-335 33 2.8e-61 209.88 In-house 1-256 (329) Show / Hide 
Range on Protein: 122-335
Range on HMM: 1-256/329
Sequence Identity: 33% (87 aa)

YKKCELIDKGAYGKVYKGIDTIT----NQVVAIKYIEIT-GTFEEVKKE----INSLKKEIVLLKKLN--------HQNIVKYYDFEISDDKSGVDIILE
| . . . ||..||||||.. .|    |..||.| |..     ..   |    ...||.|| ..|||.        |.||||.||.  ...   . ||.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YVPNGSLRMALNKQRC----------FDETKAAIYTKQVLEGLDYLHKNNIIHRDLKGANLLLDAE------------GRAKLTDFGTAKQIEFD-----
| . | |.  ..|..           . | .| .. || |.|. .|||.||||||.| .| |..              |..|..||| ||... |     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LRKSQVKEEDIAKMNKSLKGTPNWMAPEVIERTG----HTTS-ADIWSIGCIVIEMITGKPPY
. ...| |       | |.|||  |||..... |    .... .||||.|||  ||..||||.
MMMTCVNE-------KRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPF
Kinase 7147.AA CAMK 127-335 21 3.3e-61 195.68 In-house 1-334 (425) Show / Hide 
Range on Protein: 127-335
Range on HMM: 1-334/425
Sequence Identity: 21% (71 aa)

LIDKGAYGKVYKGIDTITN------------QVVAIKYIEITGTFEEV-----------------------KKEINSLKKEIVLLKK-------LNHQNI
 . .|..|||...|.. |.            | |||| |. .   . .                        |   ....|| ..||       |.| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKYYD-FE------------ISDD-----KSGVDIIL---EYVPNG----SLRMALNKQRC---------------FDETKAAIYTKQVLEGLDYLHKNN
.| |. .|              ..     .. . ...   ||...|     |   . ...|               |.|  |. | .|......|.|..|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDLKGANLLLDAE-----------------GRAKLTDFGTAKQIEFD----LRKSQVKEEDI---------AKMNKSLKGTPNWMA-PEVIER----
|.|||||  |.|||                   .  |..||| |.... .      ...  .| .          .. |   |||  || |||...    
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-MHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

----------TGHTTSADIWSIGCIVIEMITGKPPY
          .... ..|.||.|.|   | .|.||.
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF
Kinase 7147.AA Pkinase_Tyr 122-351 29 1.3e-27 94.14 Pfam 1-233 (270) Show / Hide 
Range on Protein: 122-351
Range on HMM: 1-233/270
Sequence Identity: 29% (73 aa)

YKKCELIDKGAYGKVYKGIDT----ITNQVVAIKYIEITGTFEEVKKE---INSLKKEIVLLKKL-NHQNIVKYYDFEISDDKS-GVDIILEYVPNGSLR
 .. . . .||.|.||||. .     |.. ||.| .      |   .|   . .. .|. ..|.| .|.|||..|   ......  . |..||.|.|.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK-----EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

MALNK----QRCFDETKAAIYTKQVLEGLDYLHKNNIIHRDLKGANLLLDAEGRAKLTDFGTAKQIEFDLRKSQVKEEDIA-KMNKSLKGTPNWMAPEVI
  | |    .. ..      .  |. .|..||. .|.|||||   | |.. .. .| .||| |. |          ..|   .. .. |    |||||.|
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI---------YNDDYYYRKRGGGKLPIKWMAPECI

ERTGHTTSADIWSIGCIVIEMIT-GKPP-YPGLSAKEVFTKI-ASGG
     ||  |.|| |    |..| |. | |||.|  ||. .|  .|.
NYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY
Kinase 7147.AA TyrKc 122-377 25 8.2e-21 76.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 122-377
Range on HMM: 1-280/280
Sequence Identity: 25% (78 aa)

YKKCELIDKGAYGKVYKGIDTITNQVVAIKYIEITGTFEEVKKEINSLKKEIVLLKKL--NHQNIVKYYDFEISD-----DKSGVDIILEYVPNGSLRMA
 .. . .  ||.|.||||. .   . ||.| .            .  . .|. ...||  .|.|||. |   ...         . |..||.|.|.|.  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LNKQRC-FDETKAAIYTKQVLEGLDYLHKNNIIHRDLKGANLLLDAEGRAKLTDFGTAKQIEFD-LRKSQVKEEDIAKMN-KSLK--GTPNWMAPEVIER
| | |  .   .   .  |. .| .|||..|.|||||   | |.......| .||| .. |. |  .   . .. . |.  |. |      |||||.| .
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIRWMAPECI-N

TGHTTSA-DIWSIGCIVIEMIT-GKPPYPG-----LSAKEVFTKIASG-------G-------------------CLQTDPKKRLTTSQLLKTPFILRKK
.|  |.. |.|| |    |. | |..||||     .|..||. .. .|                           | . ||..| | |..       ...
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-------HEC

I
.
F
Kinase 7147.AA STE20 352-372 76 2.7e-07 23.03 In-house 268-288 (288) Show / Hide 
Range on Protein: 352-372
Range on HMM: 268-288/288
Sequence Identity: 76% (16 aa)

CLQTDPKKRLTTSQLLKTPFI
||| ||.|| |.||||| |||
CLQKDPEKRPTASQLLKHPFI
Kinase 7147.AA CAMK 351-372 45 6.7e-07 17.51 In-house 404-425 (425) Show / Hide 
Range on Protein: 351-372
Range on HMM: 404-425/425
Sequence Identity: 45% (10 aa)

GCLQTDPKKRLTTSQLLKTPFI
..||.||.||.| .| |. |..
KMLQVDPEKRMTIEQCLNHPWM
Kinase 7147.AA MEKK15 352-372 61 0.001084 9.3 In-house 244-264 (264) Show / Hide 
Range on Protein: 352-372
Range on HMM: 244-264/264
Sequence Identity: 61% (13 aa)

CLQTDPKKRLTTSQLLKTPFI
||  | . | | ||||| |||
CLTRDQHERPTASQLLKHPFI
Kinase 7147.AA ULK 351-372 31 0.004602 6.64 In-house 308-329 (329) Show / Hide 
Range on Protein: 351-372
Range on HMM: 308-329/329
Sequence Identity: 31% (7 aa)

GCLQTDPKKRLTTSQLLKTPFI
..|| |.|.| .  .|.. |..
RMLQYDEKDRISWEELFNHPWF
Kinase 7147.AA ULK 351-372 27 0.00905 5.73 In-house 303-324 (324) Show / Hide 
Range on Protein: 351-372
Range on HMM: 303-324/324
Sequence Identity: 27% (6 aa)

GCLQTDPKKRLTTSQLLKTPFI
..|| |.|.| .  .... |..
RMLQYDEKDRISWEEIFNHPWF
Kinase 7147.AA Dicty2 352-372 47 0.036805 3.52 In-house 244-264 (264) Show / Hide 
Range on Protein: 352-372
Range on HMM: 244-264/264
Sequence Identity: 47% (10 aa)

CLQTDPKKRLTTSQLLKTPFI
| . || .| | .|||. | |
CFCKDPNQRMTAKQLLHHPWI