29596

Species: Tetrahymena
Alias: 29596, 759, PreTt29596, TTHERM_01246760, 289.m00023
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: MST

Sequence

Name Sequence Type Origin Length Description Download
29596.AA Protein None 1193 None Fasta, JSON
29596.kin_dom Protein Kinase Domain None 251 None Fasta, JSON
29596.NA RNA None 3582 None Fasta, JSON

Protein domain

Protein domains of 29596.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 29596.AA MST 21-271 63 9.5e-217 695.59 In-house 1-254 (254) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-254/254
Sequence Identity: 63% (162 aa)

FEILDLLGEGSYGQVYKALHKQTGELVAVKMVPNEGD-SALEKEIRMLKECQSEYVVKYYASYY--KDQHLWLIMEYCAAGSIIDLVKITRIQLNEQQIA
|.|...||.||||.||||.|||||..||.||||...| ....|||.....|.|.|.||||.||.  |..|.|..||||..||..|..|||...|||||||
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQIA

SILQSTLKGLQYLHSNKIIHRDIKAGNILLDQRGNAKLADFGVSFQQIHTQAKAESKIGTPCWMAPEVIMHLKYDSKADIWSLGITAIELAEGEPPYSDV
.||..||.||||||.||.||||||||||||...|..||||||||.|...|.||....||||.|||||||...|||.|||||||||||||.|||.|||||.
CILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSDI

KPSMVMAKIQQKPPQGLKNPSQWSQQFNDFVKQCLQQDPQKRPTAEQLLQHPFI
.|...|..|.||||...|.|.||||.|||||..|||..|..|.|||||||||||
HPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI

Kinase 29596.AA STE20 21-271 50 1.7e-159 536.18 In-house 1-288 (288) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-288/288
Sequence Identity: 50% (144 aa)

FEILDLLGEGSYGQVYKALHKQTGEL----VAVKMVPNEGD-------SALEKEIRMLKECQSEYVVKYYASYYKD----QHLWLIMEYCAAGSIIDLVK
.|.|. .|.||||.|||| ||.|||.    ||.|... | .         ..|||...|.|.....|||| ||.||    ..||..||||..||. |..|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---ITRI-----QLNEQQIASILQSTLKGLQYLHSNKIIHRDIKAGNILLDQRGNAKLADFGVSFQQIH----TQA-KAESKIGTPCWMAPEVIMH----
   .. .      .||.||| |.. .|.||.|||||.||||||||.||||...|..|||||||. | ..    |.. |  . .|||.|||||||.     
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-LKYDSKADIWSLGITAIELAEGEPPYSDVKPSMVMAKIQ--QKPPQGLKN--PSQWSQQFNDFVKQCLQQDPQKRPTAEQLLQHPFI
  .||.|.|||||||||||.|||||||.|. |  .| .|   |.||  ||.  |..||..|.|||..|||.||.|||||.|||.||||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI

Kinase 29596.AA STE 21-271 34 5.9e-133 447.99 In-house 1-359 (359) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-359/359
Sequence Identity: 34% (125 aa)

FEILDLLGEGSYGQVYKALHK------QTGEL---------VAVKMVPNEGDS--------------------ALEKEIRMLKECQ--SEYVVKYYASYY
.|... .|.|..|.||||...      .|||.         .|.| .. | ..                     ..|||...|.|.  ....|||| .|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KD-------QHLWLIMEYCAAGSIIDLVK---ITRIQLN----------EQQIASILQSTLKG-LQYLHSNKIIHRDIKAGNILLDQRGNAKLADFGVSF
|.       ..||..|||...||. |..|   ..  .||          |.||| |....||| |.||||..|||||||..||||     .||.||||. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QQIH---------------TQA-KAESKIGTPCWMAPEVIMH------LKYDSKADIWSLGITAIELAEGEPPYSDVKPSMVMAKIQQK-----------
| ..               |.. |  . .||| |||||||.        .|| |.||||||.|.||.|.|.||..| .|  .|  |...           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PPQGLKN-----------------PSQWSQQFNDFVKQCLQQDPQKRPTAEQLLQ--HPFI
    ||  |..                 |..||. |.||...||| ||.|||||.|||.  ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase 29596.AA YSK 21-271 48 1.2e-124 377.39 In-house 1-257 (257) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-257/257
Sequence Identity: 48% (126 aa)

FEILDLLGEGSYGQVYKALHKQTGELVAVKMVPNEGDS----ALEKEIRMLKECQSEYVVKYYASYYKDQHLWLIMEYCAAGSIIDLVKITRI-QLNEQQ
| ...  | ||.| |||.  ..|.. ||.| .  | ..     . .||  | .| | |. |||.|| ||  || |||||. ||. || |   . |. |..
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

IASILQSTLKGLQYLHSNKIIHRDIKAGNILLDQRGNAKLADFGVSFQQIHTQAKAESKIGTPCWMAPEVIMH--LKYDSKADIWSLGITAIELAEGEPP
|| ||   |||| ||||.. ||||||| |.||   |. ||.||||. |   || | .  .||| |||||||.    .||.|||||||||||.|.| ||||
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPP

YSDVKPSMVMAKIQQKPPQGLKNPSQWSQQFNDFVKQCLQQDPQKRPTAEQLLQHPFI
|.|..|  ||  |  ..|  |.  ...|  | .||  ||  ||..||.|..|| | ||
YCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI

Kinase 29596.AA PAKL 21-271 50 1.4e-119 403.6 In-house 1-256 (256) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-256/256
Sequence Identity: 50% (129 aa)

FEILDLLGEGSYGQVYKALHKQTGELVAVKMVP-NEG-D-SALEKEIRMLKECQSEYVVKYYASYYKD-QHLWLIMEYCAAGSIIDLVKITRIQLNEQQI
||.   ||.|||| ||||.|| |.   |.|  .  |  .   .|||| .|| | . ..| |. |      |.|  |.||..||| |. ...   ||| ||
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQI

ASILQSTLKGLQYLHSNKIIHRDIKAGNILLDQRGNAKLADFGVSFQQIHTQAK--AESKIGTPCWMAPEVIMHLKYDSKADIWSLGITAIELAEGEPPY
. ||| ||||| ||||  |||||||| ||||.  .  |.|||||| ||. .     | . |||| |||||.|    |..|.|||||||||||.|.|.|| 
SVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVS-QQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPH

SDVKPSMVMAKIQQKPPQGLKNPSQWSQQFNDFVKQCLQQDPQKRPTAEQLLQHPFI
.|. |   |  |  .||  ..||  ||  ||||. ||.. || ||. . .|| ||||
YDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI

Kinase 29596.AA Ste20-DD1 21-271 46 2.1e-101 343.17 In-house 1-268 (268) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-268/268
Sequence Identity: 46% (125 aa)

FEILDLLGEGSYGQVYKA-------LHKQTGELVAVKMVPNEG-----DSALEKEIRMLKEC-QSEYVVKYYASYYKDQHLWLIMEYCAAGSIIDLVKIT
| |.   | ||.| |                ...|.| |  ..      | | |||  ||.     |.|||   | |.  |  .||||  ||| | ... 
FQIVEVIGQGSFGVVCTCRWMKKKDRNTNNNRVIACKFVEMNADDVEENSNLKKEIDILKNTMDCPYIVKYHGCYIKENMLMIVMEYCDGGSILDIMQMC

RIQLNEQQIASILQSTLKGLQYLHSNKIIHRDIKAGNILLDQRGNAKLADFGVSFQQIHTQAKAESKIGTPCWMAPEVIMH----LKYDSKADIWSLGIT
 . | | ||| |.    ||| |||||.|.||||||||.|... | .||||||||     .  |    || | ||.||.||       ||.||||||||||
SKRLIEEQIAAICYQIVKGLVYLHSNRITHRDIKAGNVLVNKEGQPKLADFGVSTIAVNQGFKMNTVIGSPYWMSPEIIMPPKGSQGYDQKADIWSLGIT

AIELAEGEPPYSDVKPSMVMAKIQQKPPQGLKNPSQWSQQFNDFVKQCLQQDPQKRPTAEQLLQHPFI
|||.||  ||  .| |. |   |  ..|  || || ||  ||||.||||  .| ||| | ||| ||||
AIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCLNMNPDKRPSAQQLLNHPFI

Kinase 29596.AA S_TKc 21-271 34 5e-100 339.54 SMART 1-231 (231) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-231/231
Sequence Identity: 34% (91 aa)

FEILDLLGEGSYGQVYKALHKQTGELVAVKMVPNEGDSALEKEIRMLKECQSEYVVKYYASYYKDQHLWLIMEYCAA--GSIIDLVKITRIQ-----LNE
.|||...|.|..|.|||. || ||..||.|...      ...||..||. . ...||.| ...  .||...||||    |.  |. |  . .     ..|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

QQIASILQSTLKGLQYLHSNKIIHRDIKAGNILLDQRGNAKLADFGVSFQQIHTQAKAESKIGTPCWMAPEVIMHLKYDS-KADIWSLGITAIELAEGEP
 ....... ....|.|.||..|||||.|  |||||.  . |..|||.. |         . .||| .|||||.   .|.  |.|.||.|.. .|.. |.|
-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYP

PYSDVKPSMVMAKIQQKPPQGLKNPSQWSQQFNDFVKQCLQQDPQKRPTAEQLLQ-------HPFI
|..   . |.. ||              |... ||...||| ||.||||| ..||       ||..
PFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 29596.AA PAKA 21-271 41 6.5e-96 324.96 In-house 1-260 (260) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-260/260
Sequence Identity: 41% (109 aa)

FEILDLLGEGSYGQVYKALHKQTGEL--VAVKMVPNEGDSALEK---EIRMLKECQSEYVVKYYASYYKDQHLWLIMEYCAAGSIIDLVKITR-IQLN--
.. .. .|.|. |.||.|  ..|..   ||.|    . ..  |.   ||...|||. . .|.|. ||  |  ||..||| ..|.  |... .. ||.|  
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYM

-EQQIASILQSTLKGLQYLHSNKIIHRDIKAGNILLDQRGNAKLADFGVSFQQIHTQAKAESKIGTPCWMAPEVIMHLKYDSKADIWSLGITAIELAEGE
 |.||| ... .|.||...||...||||||  ||||...|. |..|||   |    | | ..  ||| |||||||   .|| | ||||||| |||..|||
DEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEGE

PPYSDVKPSMVMAKIQQK--PPQGLKNPSQWSQQFNDFVKQCLQQDPQKRPTAEQLLQHPFI
||| . .|   |  | ..  |.  .|.|  |||.|.||...||. |...|..|..||.|||.
PPYLNEPPLRAMYLIATNGKPD--IKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL

Kinase 29596.AA KHS 21-271 48 1e-95 322.44 In-house 1-258 (258) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-258/258
Sequence Identity: 48% (126 aa)

FEILDLLGEGSYGQVYKALHKQTGELVAVKMV---PNEGDSALEKEIRMLKECQSEYVVKYYASYYKDQHLWLIMEYCAAGSIIDLVKITRIQLNEQQIA
.|.|  .| | ||.|||| ..|..||.|||..   |..  . . .|| |.|.|.   .| |. || . ..||..|||| .||. |. ..|  .|.| |||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVT-GPLSELQIA

SILQSTLKGLQYLHSNKIIHRDIKAGNILLDQRGNAKLADFGVSFQQIHTQAKAESKIGTPCWMAPEVIMHLK---YDSKADIWSLGITAIELAEGEPPY
 . . ||.||.||||.. .|||||  |||| ..|. |||||||| |   | ||  | |||| ||||||    .   |.   |||..|||||||||  || 
YVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPM

SDVKPS---MVMAKIQQKPPQGLKNPSQWSQQFNDFVKQCLQQDPQKRPTAEQLLQHPFI
 |. |    ..|.| . .||. ||. ..|||.| .|||..| ..|.||||||.||||||.
FDLHPMRALFLMTKSNFQPPK-LKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV

Kinase 29596.AA SLK 21-271 45 1.7e-93 315.79 In-house 1-259 (259) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-259/259
Sequence Identity: 45% (119 aa)

FEILDLLGEGSYGQVYKALHKQTGELVAVKMVPNEGDSALEK---EIRMLKECQSEYVVKYYASYYKDQHLWLIMEYCAAGSIIDLVKITRIQLNEQQIA
.||.  ||.| .|.|||| ||... . | ||.  . .  ||    || .| ||.  ..|| | .|| |..||...|.|. | .  ..      | |.||.
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQ

SILQSTLKGLQYLHSNKIIHRDIKAGNILLDQRGNAKLADFGVSFQQIHTQAKAESKIGTPCWMAPEVIM-----HLKYDSKADIWSLGITAIELAEGEP
 . . .. .|..|||||.||||.||||||. . |. .||||||| .. ||  | .. |||| ||||||.|        || |||||||||| ||.|..||
YVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEP

PYSDVKPSMVMAKIQQKPPQGLKNPSQWSQQFNDFVKQCLQQDPQKRPTAEQLLQHPFI
|.... |  |. |||.  |  |..||.||..|.||.|.||..|||.|.|..||.||...
PHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV

Kinase 29596.AA Pkinase 21-271 30 5.7e-93 319.96 Pfam 1-293 (293) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-293/293
Sequence Identity: 30% (92 aa)

FEILDLLGEGSYGQVYKALHKQTGELVAVKMVPNEGDSALEK-------EIRMLKECQSEYVVKYYASYYKDQHLWLIMEYCAAG----SIIDLVK-ITR
..|.  .|.||.|.|||. || ||..|||| .. ....  ..       ||...|.......|..| ... ..|....||||  |    .  |...   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

IQL--NEQQIASILQSTLKGLQYLHSNKIIHRDIKAGNILLDQRGNA----KLADFGVS--FQQIHTQAKAESKIGTPCWMAPEVIM-HLKYDSKADIWS
  .   |... ...  .|.||.|.||..|||||.|  |||.|..|.     |..|||..  |. .  .  . .  ||| .||||||. . .|..|.|.||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGITAIELAEGEPPYSDV----KPSMVMAKIQQKPPQGLKNPSQWS---------------------QQFNDFVKQCLQQDPQKRPTAEQLLQHPFI
.|.. .|.. |.||...     .    |..|... .  |. ...|.                     . . ||.| ||..||.|||||||.||||..
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 29596.AA NinaC 21-271 44 2.2e-89 303.29 In-house 1-267 (267) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-267/267
Sequence Identity: 44% (119 aa)

FEILDLLGEGSYGQVYKALHKQTGELVAVKMVP--NEGDSALEKEIRMLKE-CQSEYVVKYYASYYKDQH-----LWLIMEYCAAGSIIDLVK-ITRIQ-
.||    | | || |.|.. |. |...|||     .. |   | | . |.. |    ||..|  |||  .     ||..||||. ||..|.|| . .   
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCGR

-LNEQQIASILQSTLKGLQYLHSNKIIHRDIKAGNILLDQRGNAKLADFGVSFQQIHTQAKAESKIGTPCWMAPEVI-----MHLKYDSKADIWSLGITA
 ..|. || ||  .. ||| ||.|..||||.|  |||| . |  || ||||| |   |  .    .|||||||||||         ||  .|.|||||||
RMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGITA

IELAEGEPPYSDVKPSMVMAKIQQKPPQGLKNPSQWSQQFNDFVKQCLQQDPQKRPTAEQLLQHPFI
|||. |.||  |  |   | ||   ||  |  | .|.|.||||. |||  |  |||.  ..|.||||
IELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI

Kinase 29596.AA Pkinase_Tyr 21-271 26 2.3e-48 164.44 Pfam 1-270 (270) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-270/270
Sequence Identity: 26% (72 aa)

FEILDLLGEGSYGQVYKALHK----QTGELVAVKMVPNEGDSA------LEKEIRMLKEC-QSEYVVKYYASYY-KDQH--LWLIMEYCAAGSIIDLVKI
 ...  ||||..|.|||.  |    .|.  |||||...  ..       . .|....|.  . . .|..|.  . ....  ....|||.. |.  |  . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

T---RIQLNEQQIASILQSTLKGLQYLHSNKIIHRDIKAGNILLDQRGNAKLADFGVSFQQIHTQ---AKAESKIGTPCWMAPEVIMHLKYDSKADIWSL
    . .|. ... .. .   ||..||.|...||||. | |.|..  . .| .||| .    ..     |...      |||||.|.. |. .| |.|| 
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GITAIELAE-GEPP-YSDVKPSMVMAKI-QQKPPQGLKNPSQWSQQFNDFVKQCLQQDPQKRPTAEQLLQHPFI
|..  |.   || | | ..... |...| ..     .. |   ..   |  ||| ..||..||| ...  | ..
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL

Kinase 29596.AA TyrKc 21-271 25 9.4e-34 119.38 SMART 1-280 (280) Show / Hide
Range on Protein: 21-271
Range on HMM: 1-280/280
Sequence Identity: 25% (73 aa)

FEILDLLGEGSYGQVYKALHKQTGELVAVKMVPNEGDSALEKEIRMLKEC--QSEYVVKYYASYYKD-------QHLWLIMEYCAAGSIIDLVKITRIQL
 . .. |||| .|.|||.  |   . |||||. ..   .. .|.|....   . . .|. |.   ..       . |...|||.. |.  |  . .| .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKL

NEQQIASILQSTLKGLQYLHSNKIIHRDIKAGNILLDQRGNAKLADFGVSFQQIHT-------QAKAESK-IGTP--C---WMAPEVIMHLKYDSKADIW
. ..  |.     .| .||||...||||. | |.|.. .. .| .||| |    .        . .  ..  |.       |||||.|.. |. .| |.|
CMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVW

SLGITAIELAE-GEPPYSD-----VKPSMVMAKIQQKPPQGLKNPSQ--------WSQQFNDFVKQCLQQDPQKRPTAEQLLQHPFI
| |..  |.   |..||..     .... |.....|     .. |           ..   .  ||| . || .||| ...  | ..
SFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG--YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF