Gene AktB (Sea Urchin)

AktB

Species: Sea Urchin
Alias: AktB, SPU_017694, Spk001
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
AktB.AA Protein None 358 None Fasta, JSON
AktB.kin_dom Protein Kinase Domain None 260 None Fasta, JSON

Protein domain

Protein domains of AktB.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AktB.AA Akt 48-307 58 1.9e-193 623.84 In-house 1-264 (264) Show / Hide 
Range on Protein: 48-307
Range on HMM: 1-264/264
Sequence Identity: 58% (155 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVF-AIKVFKKEAFLQEDEVELENSLTKNRMVQKISHPFLASLEYLFQTSDRLYFVMEYVNGGELFFHLSRDRVFT
||.|||||||. |||.| ..|.|.... |.|| ||.  .| .  ..|. .| ... |.. |||. .| | |||.|.|||||.|.||||||.||.|.|.|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKN--QVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFS

EERARFYCAEIVSALSYLHAQDVIYRD-MKLENILLDSEGHIKITDFGLCKQE-ISYSDTTKTFCGTPEYLAPEILDENDYGMAVDWWG-TGVVMYEMMC
|.|||||||||..|. .|| ...|||| .|.||||.|..|||..|||||||.. |.. |.||||||||||||||||. |....|||||| .|.|||||||
EDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMC

GRLPFYNRDHEVLFNLILKEEVRFP--NRLSEEAKSLLSGLLEKDPKKRLGYGPDDAKEIMRHPFF
||.||||.||...| .|. ..|.||  ...| |.|.|.||||.||||||||.||.||.||.|||.|
GRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase AktB.AA AGC 48-307 35 2.4e-182 476.46 In-house 1-395 (395) Show / Hide 
Range on Protein: 48-307
Range on HMM: 1-395/395
Sequence Identity: 35% (142 aa)

FDVLKVLGKGTLGKVVLGREK------KTGEVFAIKVFKKEA-FLQEDEVELENSLTK------------NRMVQKIS----------HPFLAS-LEYLF
|..|||.|||. ||| | |.|       ||...|.|| ||.   .. .. ..|. .|              .. .|..          |||. . | | |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTSDR--LYFVME----YVN-----GG-ELFFHLS---RDRVFTEERARFYCAE-------IVSALSYLHA-QDVIYRD-MKLENILLDSEGHIKITDFG
|. |.  ||||||    |||     || |||.||    . ..|.|||||||.||       ||.|| |||  ...|.|| .|.||||||..||||.||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKQEISYS--------------------------------------------------DTTKTFCG--TPEYLAPEILDENDYGMAVDWWG--TGVVMY
|||. ...                                                   |.|.||||  ||||.|||||    || |.|||.   |..||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMMCGRLPFYNR----------DHEVLFNLIL------KEEVRFP----------NRLSEEAKSLLSGLLEKDPKKRLGYGPDD-----AKEIMRHPFF
||..|. |||.           ... .|..|.      ...|.||            .|.|||.|...||.|||.||||.|..|     |.||..||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase AktB.AA SGK 48-307 47 1e-144 450.13 In-house 1-283 (283) Show / Hide 
Range on Protein: 48-307
Range on HMM: 1-283/283
Sequence Identity: 47% (136 aa)

FDVLKVLGKGTLGKVVLGREKKT------------------GEVFAIKVFKKEAFLQEDEVELENSLTKNRMVQK------ISHPFLASLEYLFQTSDRL
|| |||.|||  ||| . . |..                  . ..|.|| .|.. . |   .| . . |. |  .      ..|||. .| | ||| . |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YFVMEYVNGGELFFHLSRDRVFTEERARFYCAEIVSALSYLHAQDVIYRDMKLENILLDSEGHIKITDFGLCKQEISYSDTTKTFCGTPEYLAPEILDEN
||||.||||||.|.|| | . | | ||||| ||||.|| ||| ||.|||| | ||||||..||...|||||||..|  .|||.||||||||||||.|   
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

DYGMAVDWWGTGVVMYEMMCGRLPFYNRDHEVLFNLILKEEVRFPNRLSEEAKSLLSGLLEKDPKKRLGYGPDDAKEIMRHPFF
 .. .||||  | |.|||| |  |||.|... ..  |.... ..|   | .|..|. |||.||||||||   .|. || .||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF
Kinase AktB.AA PKC 48-307 52 4.2e-140 456.92 In-house 1-262 (262) Show / Hide 
Range on Protein: 48-307
Range on HMM: 1-262/262
Sequence Identity: 52% (139 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKEAFLQEDEVELENSLTKNRMVQKISHPFLASLEYLFQTSDRLYFVMEYVNGGELFFHLSRDRVFTE
|. |||||||  |||.|.. |.| |..|||| ||....| | ||      |  . .   |||| .|   ||| |||.||||||||| | ||  . | | |
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVEC-TMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKE

ERARFYCAEIVSALSYLHAQDVIYRDMKLENILLDSEGHIKITDFGLCKQEISYSDTTKTFCGTPEYLAPEILDENDYGMAVDWWGTGVVMYEMMCGRLP
|.|||| |||..|| .|| ...|||| ||.|.|||.||||||.|||.||... . |||.||||||.|.||||| . .|| .||||  || |||||.|. |
EHARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSP

FYNRDHEVLFNLILKEEVRFPNRLSEEAKSLLSGLLEKDPKKRLGYGPDD---AKEIMRHPFF
|   | . ||. |.......|  ||.||.|...|...|.|.|||| .|..   ...|..||||
FHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase AktB.AA Eta 48-307 53 4e-118 398.72 In-house 1-261 (261) Show / Hide 
Range on Protein: 48-307
Range on HMM: 1-261/261
Sequence Identity: 53% (140 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKEAFLQEDEVELENSLTKNRMVQ-KISHPFLASLEYLFQTSDRLYFVMEYVNGGELFFHLSRDRVFT
|. .||||||  |||.| . | |.||.|||| ||.. .|.|.||    .|  |..     |||| .|   |||.|||.|||||||||.| |.. | | | 
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVEC--TMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFD

EERARFYCAEIVSALSYLHAQDVIYRDMKLENILLDSEGHIKITDFGLCKQEISYSDTTKTFCGTPEYLAPEILDENDYGMAVDWWGTGVVMYEMMCGRL
| ||||| ||...|| .|| ..|||||.||.||||| ||| |. |||.||  |    || ||||||.|.||||| | .|| .||||  ||.|||||||. 
EPRARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQP

PFYNRDHEVLFNLILKEEVRFPNRLSEEAKSLLSGLLEKDPKKRLGYGP--DDAKEIMRHPFF
||     . ||. ||...| .|  |..|| |.| . . | |.||||     .. ..| .||||
PFEADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF
Kinase AktB.AA RSK 51-307 44 1.2e-117 397.1 In-house 1-278 (278) Show / Hide 
Range on Protein: 51-307
Range on HMM: 1-278/278
Sequence Identity: 44% (124 aa)

LKVLGKGTLGKVVLGREK---KTGEVFAIKVFKKEAFLQE--DEVELENSLTKNRMVQKIS-HPFLASLEYLFQTSDRLYFVMEYVNGGELFFHLSRDRV
|||||.|  ||| | |..   .|| ..| || ||  . |   |   ..  .|  .  . .  |||. .| | ||| . || .|||..||||| ||.. . 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKD---TRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKH

---FTEERARFYCAEIVSALSYLHAQDVIYRDMKLENILLDS---EGHIKITDFGLCKQ-EISYSDTTKTFCGTPEYLAPEILD----ENDYGMAVDWWG
   |.|..|.|| ||||.|...|| |..|.|| |.||||.|.   |||||.||||.|||  ....  |.|||.| ||.|||.|     .. .. |.||| 
FGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWS

TGVVMYEMMCGRLPFYN---RDHEVLFNLILKEE--VRFP--NRLSEEAKSLLSGLLEKDPKKRLGYGPDDAKEIMRHPFF
 ||.||||  |..||..    ....... |.| .  ...|  . ||.|||.|....|..||.||||.||.||.|| .||.|
LGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase AktB.AA AktR 48-307 44 8.99999999999e-114 384.28 In-house 1-268 (268) Show / Hide 
Range on Protein: 48-307
Range on HMM: 1-268/268
Sequence Identity: 44% (119 aa)

FDVLKVLGKGTLGKVVLGREK-KTGEVFAIKVFKKEAFLQEDEVELENSLTKNRMVQKISHPFLASLEYLFQTSDRLYFVMEYVNGGELFFHLSRDRVFT
|.|.|.||||. |||.| ..| ......|.|. ||  ...| . .    . .| |  ...|||.  |.| ||| . |.|.|||. |||||.||.... |.
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKK-KKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFS

EERARFYCAEIVSALSYLHAQ-DVIYRDMKLENILLDSEGHIKITDFGLCK-QEIS-YSDTTKTFCGTPEYLAPEILDE-NDYGMAVDWWGTGVVMYEMM
||.|||| |.|. || ||| . ..||||.| ||||||..||.||||||| | | .  |......|||||||.|||.. .   .. .||||  |.. |||.
EEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMV

CGRLPFYNRDHEVLFNLILKEE-VRFPNR--LSEEAKSLLS-GLLEKDPKKRLGYGPDDAKEIMRHPFF
 |  |||. ... .| .|.... ..||    .|...|.|.  .|| |.|.|||||.  ...|| .||.|
TGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase AktB.AA Alpha 48-307 49 2.6e-112 379.45 In-house 1-259 (259) Show / Hide 
Range on Protein: 48-307
Range on HMM: 1-259/259
Sequence Identity: 49% (129 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKEAFLQEDEVELENSLTKNRMVQKISHP-FLASLEYLFQTSDRLYFVMEYVNGGELFFHLSRDRVFT
|  |.|||||  ||| |.  | | | .|||. ||    |.| ||.   ..  |     . | || ..   ||| ||||||||||||| | .|. .   | 
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVEC--TMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFK

EERARFYCAEIVSALSYLHAQDVIYRDMKLENILLDSEGHIKITDFGLCKQEISYSDTTKTFCGTPEYLAPEILDENDYGMAVDWWGTGVVMYEMMCGRL
|  | || |||  .| .|| ...||||.|| |..||.||||||.|||.|| ..   .||.||||||.|.||||   . || .||||  || .|||| |  
EPHAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQP

PFYNRDHEVLFNLILKEEVRFPNRLSEEAKSLLSGLLEKDPKKRLGYGPDDAKEIMRHPFF
||   | . ||  |   .| .|  .| ||...  |.| | | |||| |||. ..|  ||||
PFDGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGEQDIREHPFF
Kinase AktB.AA S_TKc 48-307 38 2.2e-105 357.34 SMART 1-231 (231) Show / Hide 
Range on Protein: 48-307
Range on HMM: 1-231/231
Sequence Identity: 38% (104 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKEAFLQEDEVELENSLTKNRMVQKISHPFLASLEYLFQTSDRLYFVMEYVNG--GELFFHLSRDRV-
...|...|||. ||| ..|.||||...|||. |       . .. | .. |.       ||..  | . ||. |.||.||||..|  |.|| .. . .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----FTEERARFYCAEIVSALSYLHAQDVIYRDMKLENILLDSEGHIKITDFGLCKQEISYSDTTKTFCGTPEYLAPEILDENDYGM-AVDWWGTGVVM
     |.| .||||...|..|| |.| . .|.|| | ||||||.  ||||.||||..|        .||||||.|.|||.|    ||  ..|||  |...
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

YEMMCGRLPFYNRDHEVLFNLILKEEVRFPNRLSEEAKSLLSGLLEKDPKKRLGYGPDDA--KEIMRHPFF
|||.||. ||.  .....|..|.          |.|||......|.|||.||..     .   .|. ||.|
YEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AktB.AA Delta 48-307 45 3.1e-104 352.6 In-house 1-259 (259) Show / Hide 
Range on Protein: 48-307
Range on HMM: 1-259/259
Sequence Identity: 45% (118 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKEAFLQEDEVELENSLTKNRMVQKISHPFLASLEYLFQTSDRLYFVMEYVNGGELFFHLSRDRVFTE
| ..||||||  |||.|.  |.. . .|||  ||.  |..|.||    . .  .     ||||. |   ||| . |.|||||.|||.| .|.   . | |
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVEC-TMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDE

ERARFYCAEIVSALSYLHAQDVIYRDMKLENILLDSEGHIKITDFGLCKQEISYSDTTKTFCGTPEYLAPEILDENDYGMAVDWWGTGVVMYEMMCGRLP
.||||| .||...| .|| ...||||.||.|.||| .||||| |||.||...    ...||||||.|.||||.  . |  .||||  ||.||||. |  |
KRARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSP

FYNRDHEVLFNLILKEEVRFPNRLSEEAKSLLSGLLEKDPKKRLGYGPDDAKEIMRHPFF
|  .| . ||. |....  .|  ...|||..|..|.|.||.||||     . .| .|.||
FHGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase AktB.AA PKN 48-307 49 5e-101 341.93 In-house 1-260 (260) Show / Hide 
Range on Protein: 48-307
Range on HMM: 1-260/260
Sequence Identity: 49% (130 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKEAFLQEDEVE-LENSLTKNRMVQKISHPFLASLEYLFQTSDRLYFVMEYVNGGELFFHLSRDRVFT
| .. |||.|  |||.| . |.|||..|||. ||.  .  |||| |        .|... |||| .|   |||..  .|||||. ||.|  |.  | ||.
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHED-VFS

EERARFYCAEIVSALSYLHAQDVIYRDMKLENILLDSEGHIKITDFGLCKQEISYSDTTKTFCGTPEYLAPEILDENDYGMAVDWWGTGVVMYEMMCGRL
| ||.|| | .|  | ||| . .||||.||.|.||| ||..|| ||||||  . | | | |||||||.||||.| .. |  |||||| ||..|||. |  
EPRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGEC

PFYNRDHEVLFNLILKEEVRFPNRLSEEAKSLLSGLLEKDPKKRLGYGPDDAKEIMRHPFF
||   | | .|. |. ..||.|  || || ...  || | |..|||.|  || .|  .|||
PFPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAEDIKMQPFF
Kinase AktB.AA Pkinase 48-307 32 2.5e-99 341.08 Pfam 1-293 (293) Show / Hide 
Range on Protein: 48-307
Range on HMM: 1-293/293
Sequence Identity: 32% (100 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKEAFLQEDEVEL----ENSLTKNRMVQKISHPFLASLEYLFQTSDRLYFVMEYVNGG----ELFFHL
. .....|.|. |.| ....|.||...|.|..||.    . ....    | .. |.       ||.   | . |...|..|.||||..||    .|| ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-----HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

S--RDRVF--TEERARFYCAEIVSALSYLHAQDVIYRDMKLENILLDSEGHI----KITDFGLCKQ--EISYSDTTKTFCGTPEYLAPEILD-ENDYGMA
|  |...|  .|. ..||. .|...| |.|.. .|.||.|.||||.|..|||    ||.||||.||  . ..|  ..||||||.|.|||..   ..|| .
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPK

VDWWGTGVVMYEMMCGRLPFYNR------DHEVLFNLILKEEVRFPNRLS---------------------EEAKSLLSGLLEKDPKKRLGYGPDDAKEI
||.|. |...|||.|||.||...      |. .....|.. ...|.   .                     ||.|......|.||||||..     |..|
VDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQI

MRHPFF
. ||.|
LQHPWF
Kinase AktB.AA Akt 4-42 52 4.1e-19 57.67 In-house 1-40 (264) Show / Hide 
Range on Protein: 4-42
Range on HMM: 1-40/264
Sequence Identity: 52% (21 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVF-AIKVFKKEAFLQ
||.|||||||. |||.| ..|.|.... |.|| ||.  .|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQ
Kinase AktB.AA PKC 4-42 56 6.3e-15 44.66 In-house 1-39 (262) Show / Hide 
Range on Protein: 4-42
Range on HMM: 1-39/262
Sequence Identity: 56% (22 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKEAFLQ
|. |||||||  |||.|.. |.| |..|||| ||....|
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQ
Kinase AktB.AA AGC 4-38 48 8.6e-15 33.2 In-house 1-41 (395) Show / Hide 
Range on Protein: 4-38
Range on HMM: 1-41/395
Sequence Identity: 48% (20 aa)

FDVLKVLGKGTLGKVVLGREK------KTGEVFAIKVFKKE
|..|||.|||. ||| | |.|       ||...|.|| ||.
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKK
Kinase AktB.AA Eta 4-43 55 2.6e-14 45.13 In-house 1-40 (261) Show / Hide 
Range on Protein: 4-43
Range on HMM: 1-40/261
Sequence Identity: 55% (22 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKEAFLQE
|. .||||||  |||.| . | |.||.|||| ||.. .|.
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQD
Kinase AktB.AA TyrKc 48-307 22 2.7e-14 8.43 SMART 1-280 (280) Show / Hide 
Range on Protein: 48-307
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKEAFLQEDEVELENSLTKNRMVQKI--SHPFLASLEYLFQTS-------DRLYFVMEYVNGGELFFH
   .|.|| |  |.|..|. |   .  |.|. |..|   . .   |      |.  |.  .|| .  |     ..       . |. ||||. .| |  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMRE-----ARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LSRDRV-FTEERARFYCAEIVSALSYLHAQDVIYRDMKLENILLDSEGHIKITDFGLCKQEISY-------SDTTKTF--CGTP----EYLAPEILDEND
| . |  .. .    .|  | .  .||| . .| ||    |.|.......||.||||..   ..       .  .|.   .|        .||| .... 
LRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YGMAVDWWGTGVVMYEMM-CGRLPFYN------RDHEVLFNLILKEEVRFPNR--------LSEEAKSLLSGLLEKDPKKRLGYGPDDAKEIMRHPFF
.  . | |  ||.|.|..  |  | ..       . ||. ..   .  . |           ..|  .. .   . ||..|        .||  | .|
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP-----TFSEI--HECF
Kinase AktB.AA AktR 4-45 37 1.9e-11 40.64 In-house 1-43 (268) Show / Hide 
Range on Protein: 4-45
Range on HMM: 1-43/268
Sequence Identity: 37% (16 aa)

FDVLKVLGKGTLGKVVLGREK-KTGEVFAIKVFKKEAFLQETM
|.|.|.||||. |||.| ..| ......|.|. ||. . ....
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQ
Kinase AktB.AA Pkinase_Tyr 48-260 23 3.6e-11 38.44 Pfam 1-228 (270) Show / Hide 
Range on Protein: 48-260
Range on HMM: 1-228/270
Sequence Identity: 23% (55 aa)

FDVLKVLGKGTLGKVVLGREK----KTGEVFAIKVFKKEAFLQED--EVELENSLTKNRMVQKI-SHPFLASLEYLFQ-TSDR--LYFVMEYVNGGELFF
   .|.||.|  |.|..|. |    .|.   |.|.  ||   .|.    .. . .   ..  .. .|| . .|       ..   .| ||||. .| |  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREA---KIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

HLSR----DRVFTEERARFYCAEIVSALSYLHAQDVIYRDMKLENILLDSEGHIKITDFGLCKQEIS---Y-SDTTKTFCGTPEYLAPEILDENDYGMAV
.| .    .. .| ..   .|..| ....||...  | ||    |.|.......||.||||..   .   |   ....       .||| . .. .  . 
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKS

DWWGTGVVMYEMMC-GRLP-FYNRDHEVLFNLI
| |  ||.|.|..  |. | ... . | ....|
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI
Kinase AktB.AA SGK 4-47 29 1.2e-10 28.65 In-house 1-62 (283) Show / Hide 
Range on Protein: 4-47
Range on HMM: 1-62/283
Sequence Identity: 29% (18 aa)

FDVLKVLGKGTLGKVVLGREKKT------------------GEVFAIKVFKKEAFLQETMDD
|| |||.|||  ||| . . |..                  . ..|.|| .|.. . |   |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQD
Kinase AktB.AA Alpha 4-43 50 2.8e-10 32.05 In-house 1-40 (259) Show / Hide 
Range on Protein: 4-43
Range on HMM: 1-40/259
Sequence Identity: 50% (20 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKEAFLQE
|  |.|||||  ||| |.  | | | .|||. ||    |.
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQD
Kinase AktB.AA S_TK_X 308-357 26 5.2e-10 40.49 SMART 1-79 (79) Show / Hide 
Range on Protein: 308-357
Range on HMM: 1-79/79
Sequence Identity: 26% (21 aa)

APINWEDIFE--KKVQPPFKPEIK----SDADTTYFDRDFTQERARLTPPPA-----------------------GKDT
. |.|....   |...|||||.||    |. || .|| .|| | ..|||..                         .. 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase AktB.AA PKN 4-38 51 8.2e-10 29.59 In-house 1-35 (260) Show / Hide 
Range on Protein: 4-38
Range on HMM: 1-35/260
Sequence Identity: 51% (18 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKE
| .. |||.|  |||.| . |.|||..|||. ||.
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQ
Kinase AktB.AA Delta 4-43 45 1.7e-09 30.49 In-house 1-40 (259) Show / Hide 
Range on Protein: 4-43
Range on HMM: 1-40/259
Sequence Identity: 45% (18 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKEAFLQE
| ..||||||  |||.|.  |.. . .|||  ||.  |..
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLED
Kinase AktB.AA Pkinase 4-38 31 4.6e-08 29.58 Pfam 1-35 (293) Show / Hide 
Range on Protein: 4-38
Range on HMM: 1-35/293
Sequence Identity: 31% (11 aa)

FDVLKVLGKGTLGKVVLGREKKTGEVFAIKVFKKE
. .....|.|. |.| ....|.||...|.|..||.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR
Kinase AktB.AA Pkinase_C 327-358 40 1.4e-07 29.96 Pfam 1-31 (46) Show / Hide 
Range on Protein: 327-358
Range on HMM: 1-31/46
Sequence Identity: 40% (13 aa)

EIKSDADTTYFDRDFTQERARLTPPPAGKDTS
..||. || .|| .||.|....|||.    .|
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSS
Kinase AktB.AA RSK 7-42 48 1.6e-05 16.55 In-house 1-39 (278) Show / Hide 
Range on Protein: 7-42
Range on HMM: 1-39/278
Sequence Identity: 48% (19 aa)

LKVLGKGTLGKVVLGREK---KTGEVFAIKVFKKEAFLQ
|||||.|  ||| | |..   .|| ..| || ||  . |
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQ