Gene AktA (Sea Urchin)

AktA

Species: Sea Urchin
Alias: AktA, SPU_010805, Spk003
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
AktA.AA Protein None 448 None Fasta, JSON
AktA.kin_dom Protein Kinase Domain None 241 None Fasta, JSON

Protein domain

Protein domains of AktA.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH AktA.AA PH 25-73 24 1e-05 23.24 Pfam 47-92 (92) Show / Hide 
Range on Protein: 25-73
Range on HMM: 47-92/92
Sequence Identity: 24% (12 aa)

CQILKTEKP-APNTFKVRCLQWTSFIERTFSVASNDERESWVKALQGVTD
||. |....  |..|..|. ..    . .|. .| .|...|..|.| .  
CQVTKVPDNKRPHCFQIRT-DR---RTYYFQAESEEEMNDWMQAIQSACR
PH AktA.AA PH 14-24 63 5.469525 2.61 Pfam 1-11 (92) Show / Hide 
Range on Protein: 14-24
Range on HMM: 1-11/92
Sequence Identity: 63% (7 aa)

VIKEGWVQKRE
||||||. |..
VIKEGWLHKKG
Kinase AktA.AA Akt 114-354 59 1.5e-197 637.19 In-house 1-247 (264) Show / Hide 
Range on Protein: 114-354
Range on HMM: 1-247/264
Sequence Identity: 59% (148 aa)

FELLKCLGKGTFGKVIQVREKKTGELF-AIKVLKKEVIVQKDEVAHTLTENRVLQKTSHPFLTSLKYSFQTSDRLCFVMEYVNGGELFFHLSRERIFTEE
|..||.||||.||||..|..|.|.... |.|||||..|.||..|.||.||...||.. |||...|.|||||.|.|.|||.|.||||||.||.|.|.|.|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

RTRFYGAEIVSALSYLHAQDVIYRD-LKLENLLVDEEGHIKITDFGLCKEN-ISYGDMTKTFCGTPEYLAPEILEDNDYGRAVDWWG-TGVVMYEMMCGR
|.|||.|||..|. .|| ...|||| ||.||.|.|..|||..||||||||| |...|.||||||||||||||||..|....|||||| .|.|||||||||
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

LPFYSRDHEVLFDLILTENVKFP--TRLSNEAKSLLSGLLEKNPKKR
.|||..||...|..|....||||   ..|.|.|.|.||||.|.||||
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKR
Kinase AktA.AA AGC 114-354 37 1.5e-185 484.93 In-house 1-373 (395) Show / Hide 
Range on Protein: 114-354
Range on HMM: 1-373/395
Sequence Identity: 37% (143 aa)

FELLKCLGKGTFGKVIQVREK------KTGELFAIKVLKKEV-IVQKD--EVAHTLTE------------NRVLQKTS----------HPFLTS-LKYSF
||.||..|||.||||..||.|       ||...|.|||||.. ||.|.  .|.||.||             ..|.| .          |||... |.|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTSDR--LCFVME----YVN-----GG-ELFFHLS---RERIFTEERTRFYGAE-------IVSALSYLHA-QDVIYRD-LKLENLLVDEEGHIKITDFG
|. |.  |.||||    |||     || |||.||    .|..|.|||.||| ||       ||.|| |||  ...|.|| ||.||.| ||.||||.||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKENISYG--------------------------------------------------DMTKTFCG--TPEYLAPEILEDNDYGRAVDWWG--TGVVMY
||||....|                                                  |.|.||||  ||||.|||||    ||.|.|||.   |..||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMMCGRLPFYSR----------DHEVLFDLIL------TENVKFP----------TRLSNEAKSLLSGLLEKNPKKR
||..|. |||.           ... .|..|.      ...||||            .|.|||.|...||.|.|.||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKR
Kinase AktA.AA SGK 114-354 49 9.60000000001e-149 462.76 In-house 1-267 (283) Show / Hide 
Range on Protein: 114-354
Range on HMM: 1-267/283
Sequence Identity: 49% (132 aa)

FELLKCLGKGTFGKVIQVREKKT------------------GELFAIKVLKKEVIV-------QKDEVAHTLTEN-RVLQKTSHPFLTSLKYSFQTSDRL
|..|| .||| |||| ||. |..                  . ..|.|||.|. |.       .| |. |...|   .|.. .|||. .|.|.||| . |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

CFVMEYVNGGELFFHLSRERIFTEERTRFYGAEIVSALSYLHAQDVIYRDLKLENLLVDEEGHIKITDFGLCKENISYGDMTKTFCGTPEYLAPEILEDN
 |||.||||||.|.|| ||..| | | ||| ||||.|| ||| ||.|||||| ||.| | .||...||||||||.|   | |.||||||||||||.|   
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

DYGRAVDWWGTGVVMYEMMCGRLPFYSRDHEVLFDLILTENVKFPTRLSNEAKSLLSGLLEKNPKKR
 ..|.||||  | |.|||| |  |||||... ..| |. .  ..|.  ||.|..|. |||.|.||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKR
Kinase AktA.AA PKC 114-354 58 2.9e-140 457.46 In-house 1-242 (262) Show / Hide 
Range on Protein: 114-354
Range on HMM: 1-242/262
Sequence Identity: 58% (141 aa)

FELLKCLGKGTFGKVIQVREKKTGELFAIKVLKKEVIVQKDEVAHTLTENRVL-QKTSHPFLTSLKYSFQTSDRLCFVMEYVNGGELFFHLSRERIFTEE
|..|| |||| ||||. .. |.| |..|||||||.||.| | |  |.|| ||| . . |||||.|  .||| ||| ||||||||| | ||  . | | ||
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RTRFYGAEIVSALSYLHAQDVIYRDLKLENLLVDEEGHIKITDFGLCKENISYGDMTKTFCGTPEYLAPEILEDNDYGRAVDWWGTGVVMYEMMCGRLPF
..|||.|||..|| .|| ...|||||||.| |.|.||||||.|||.||||. .||.|.||||||.|.|||||.  .|| .||||  || |||||.|. ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YSRDHEVLFDLILTENVKFPTRLSNEAKSLLSGLLEKNPKKR
   | . ||. |...|. .|  || ||.|...|...|||.||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKR
Kinase AktA.AA Eta 114-354 56 3.7e-118 398.84 In-house 1-242 (261) Show / Hide 
Range on Protein: 114-354
Range on HMM: 1-242/261
Sequence Identity: 56% (136 aa)

FELLKCLGKGTFGKVIQVREKKTGELFAIKVLKKEVIVQKDEVAHTLTENRVLQ-KTSHPFLTSLKYSFQTSDRLCFVMEYVNGGELFFHLSRERIFTEE
|. .| |||| ||||.  . | |.|..|||||||.||.| |.|  |.|| |.|     |||||.|  .|||.||| |||||||||.| |.. | | | | 
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP

RTRFYGAEIVSALSYLHAQDVIYRDLKLENLLVDEEGHIKITDFGLCKENISYGDMTKTFCGTPEYLAPEILEDNDYGRAVDWWGTGVVMYEMMCGRLPF
|.||| ||...|| .|| ..||||||||.|.|.|.||| |. |||.||| |  | .| ||||||.|.|||||.. .|| .||||  ||.|||||||. ||
RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF

YSRDHEVLFDLILTENVKFPTRLSNEAKSLLSGLLEKNPKKR
     . ||. || ..| .|. |..|| |.| . . |||.||
EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKR
Kinase AktA.AA RSK 117-355 43 7e-116 391.28 In-house 1-262 (278) Show / Hide 
Range on Protein: 117-355
Range on HMM: 1-262/278
Sequence Identity: 43% (113 aa)

LKCLGKGTFGKVIQVREK---KTGELFAIKVLKKEVIVQKDE-VAHTLTENRVLQKTS-HPFLTSLKYSFQTSDRLCFVMEYVNGGELFFHLSRERI---
|| ||.| .||| ..|..   .|| ..| ||||| .|||..  ..||.|| ..|. .  |||. .|.|.||| . |  .|||..||||| ||..|..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTEERTRFYGAEIVSALSYLHAQDVIYRDLKLENLLVDE---EGHIKITDFGLCKE-NISYGDMTKTFCGTPEYLAPEILE----DNDYGRAVDWWGTGV
|.|.. .|| ||||.|...|| |..|.||||.|| | |.   |||||.||||.||. ..... .|.|||.| ||.|||.|     .. ...|.|||  ||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

VMYEMMCGRLPFYS---RDHEVLFDLILTEN--VKFP--TRLSNEAKSLLSGLLEKNPKKRY
.||||  |..||..    ....... |.. .  ...|    ||.|||.|....|...|.||.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRL
Kinase AktA.AA AktR 114-354 45 1.2e-115 390.56 In-house 1-251 (268) Show / Hide 
Range on Protein: 114-354
Range on HMM: 1-251/268
Sequence Identity: 45% (114 aa)

FELLKCLGKGTFGKVIQVREK-KTGELFAIKVLKKEVIVQKDEVAHTLTENRVLQ-KTSHPFLTSLKYSFQTSDRLCFVMEYVNGGELFFHLSRERIFTE
|...||||||.||||. |..| ......|.|..||. |...    ||.||  ... . .|||.  |.|.||| . | |.|||. |||||.||.... |.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

ERTRFYGAEIVSALSYLHAQ-DVIYRDLKLENLLVDEEGHIKITDFGLCK-ENIS-YGDMTKTFCGTPEYLAPEILED-NDYGRAVDWWGTGVVMYEMMC
|..||| |.|. || ||| . ..|||||| ||.| ||.||.||||||| | ...  | .....|||||||.|||..     ....||||  |.. |||. 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GRLPFYSRDHEVLFDLILTEN-VKFPTR--LSNEAKSLLS-GLLEKNPKKR
|  |||. ... .|..|.... .|||.   .|...|.|.  .|| |||.||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKR
Kinase AktA.AA Alpha 114-354 51 2.1e-110 373.09 In-house 1-242 (259) Show / Hide 
Range on Protein: 114-354
Range on HMM: 1-242/259
Sequence Identity: 51% (125 aa)

FELLKCLGKGTFGKVIQVREKKTGELFAIKVLKKEVIVQKDEVAHTLTENRVLQKTSHP-FLTSLKYSFQTSDRLCFVMEYVNGGELFFHLSRERIFTEE
|  |. |||| ||||.    | | ||.|||.||| ||.| | |  |..| |||   . | ||...   ||| ||| ||||||||| | .|. .   | | 
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFKEP

RTRFYGAEIVSALSYLHAQDVIYRDLKLENLLVDEEGHIKITDFGLCKENISYGDMTKTFCGTPEYLAPEILEDNDYGRAVDWWGTGVVMYEMMCGRLPF
   || |||  .| .|| ...||||||| | ..| ||||||.|||.||||.  .. |.||||||.|.||||   . ||..||||  || .|||| |  ||
HAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQPPF

YSRDHEVLFDLILTENVKFPTRLSNEAKSLLSGLLEKNPKKR
   | . ||  |   || .|  .| ||...  |.| |.| ||
DGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKR
Kinase AktA.AA PKA 114-355 44 8.9e-107 361.04 In-house 1-247 (263) Show / Hide 
Range on Protein: 114-355
Range on HMM: 1-247/263
Sequence Identity: 44% (110 aa)

FELLKCLGKGTFGKVIQVREKKTGELFAIKVLKKEVIVQKDEVAHTLTENRVLQKTSHPFLT-SLKYSFQTSDRLCFVMEYVNGGELFFHLSRERIFTEE
||... ||.|.||.| ..|.|..|. .|.|.|||. ||.   | |...|...|| ..|||.  .....||... | .|||||.|||.| .| ... |.. 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

RTRFYGA-EIVSALSYLHAQDVIYRDLKLENLLVDEEGHIKITDFGLCKENISYGDMTKTFCGTPEYLAPEILEDN-DYGRAVDWWGTGVVMYEMMCGRL
 ..|| | .||.|| |||.|. |||||| ||.| |..|||||||||  |.  .    |.| |||||||||||.     .|..||||  |.. |||. |  
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP

PFYSR--DHEVLFDLILTENVKFPTRLSNEA---KSLLSGLLEKNPKKRY
|||    |   ... |.   .|||  ... |   |.|.. ||.....|||
PFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRY
Kinase AktA.AA Delta 114-354 47 1.3e-105 357.14 In-house 1-242 (259) Show / Hide 
Range on Protein: 114-354
Range on HMM: 1-242/259
Sequence Identity: 47% (116 aa)

FELLKCLGKGTFGKVIQVREKKTGELFAIKVLKKEVIVQKDEVAHTLTENRVLQ-KTSHPFLTSLKYSFQTSDRLCFVMEYVNGGELFFHLSRERIFTEE
| ..| |||| ||||. .  |.. . .||| |||.|... |.|  |. | |||   . ||||. |  .||| . | |||||.|||.| .|.   . | |.
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

RTRFYGAEIVSALSYLHAQDVIYRDLKLENLLVDEEGHIKITDFGLCKENISYGDMTKTFCGTPEYLAPEILEDNDYGRAVDWWGTGVVMYEMMCGRLPF
|.|||..||...| .|| ...|||||||.|.|.| .||||| |||.||||.    ...||||||.|.||||.. . | ..||||  ||.||||. |  ||
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF

YSRDHEVLFDLILTENVKFPTRLSNEAKSLLSGLLEKNPKKR
  .| . ||. |. ..  .|  .. |||..|..|.|..|.||
HGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKR
Kinase AktA.AA S_TKc 114-366 37 1.4e-104 354.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 114-366
Range on HMM: 1-231/231
Sequence Identity: 37% (100 aa)

FELLKCLGKGTFGKVIQVREKKTGELFAIKVLKKEVIVQKDEVAHTLTENRVLQKTSHPFLTSLKYSFQTSDRLCFVMEYVNG--GELFFHLSRERI---
.|.|. .|||.|||| ..|.||||...|||..|           |.. | ..|.|  ||..  |...||. |.|..||||..|  |.|| .. . .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTEERTRFYGAEIVSALSYLHAQDVIYRDLKLENLLVDEEGHIKITDFGLCKENISYGDMTKTFCGTPEYLAPEILEDNDYGR-AVDWWGTGVVMYE
   |.| ..||| ..|..|| |.| . .|.|||| ||.|.||  ||||.||||...        .||||||.|.|||.|    ||. ..|||  |...||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MMCGRLPFYSRDHEVLFDLILTENVKFPTRLSNEAKSLLSGLLEKNPKKRYRNVKHCT-------TYYL
|.||. ||.  .....|..|.          | |||......|.|.|.||.   .  .         ..
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AktA.AA Pkinase 114-355 31 3.7e-100 343.86 Pfam 1-282 (293) Show / Hide 
Range on Protein: 114-355
Range on HMM: 1-282/293
Sequence Identity: 31% (91 aa)

FELLKCLGKGTFGKVIQVREKKTGELFAIKVLKKEVIVQKDEVAHTL-TENRVLQKTSHPFLTSLKYSFQTSDRLCFVMEYVNGG----ELFFHLS--RE
.......|.|.||.| . ..|.||...|.|..||. .  . ...|.. .| ..... .||.   |...|...|....||||..||    .|| ..|  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RIF--TEERTRFYGAEIVSALSYLHAQDVIYRDLKLENLLVDEEGHI----KITDFGLCKE--NISYGDMTKTFCGTPEYLAPEILE-DNDYGRAVDWWG
. |  .|.  .||  .|...| |.|.. .|.||||.||.|.|..|||    ||.||||.|   . ...  ..||||||.|.|||..  ...||..||.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

TGVVMYEMMCGRLPFYSR------DHEVLFDLILTENVKFPTRLS---------------------NEAKSLLSGLLEKNPKKRY
 |...|||.|||.||...      |. .....|.   ..|.   .                      |.|......|.|.||||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP
Kinase AktA.AA TyrKc 114-364 21 2.1e-14 10.16 SMART 1-280 (280) Show / Hide 
Range on Protein: 114-364
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

FELLKCLGKGTFGKVIQVREKKTGELFAIKVLKKEVIVQKDEVAHTLTENRVLQKT--SHPFLTSLKYSFQTS-------DRLCFVMEYVNGGELFFHLS
 .|.| || | ||.| . . |   .  |.|.||..       ..  . | |.. |   .|| .  |     ..       . |. ||||. .| |  .| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RERI-FTEERTRFYGAEIVSALSYLHAQDVIYRDLKLENLLVDEEGHIKITDFGLCKENISY-------GDMTKTF--CGTP----EYLAPEILEDNDYG
. |  .. .    .   | .  .||| . .| |||   | ||.|....||.||||...  ..          .|.   .|        .||| . .. . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

RAVDWWGTGVVMYEMM-CGRLPFYS-----RDHEVLFDLILTENVKFPTRL---------SNEAKSLLSGLLEKNPKKRYRNVKHCTTY
 . | |  ||.|.|..  |  | .       . . .. .. . .   .            . |  .. .   . .|..| .    .   
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AktA.AA Pkinase_Tyr 114-260 26 6.7e-13 44.32 Pfam 1-159 (270) Show / Hide 
Range on Protein: 114-260
Range on HMM: 1-159/270
Sequence Identity: 26% (43 aa)

FELLKCLGKGTFGKVIQVREK----KTGELFAIKVLKKEVIVQKDE--VAHTLTENRVLQKT-SHPFLTSLKYSFQ-TSDR--LCFVMEYVNGGELFFHL
 ...| ||.| ||.| . . |    .|.   |.|.| ||    ...   .  . | ... .  .|| . .|       ..   .. ||||. .| |  .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

SR----ERIFTEERTRFYGAEIVSALSYLHAQDVIYRDLKLENLLVDEEGHIKITDFGLCK
 .    .. .| ..   . ..| ....||...  | |||   | ||.|....||.||||..
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase AktA.AA Pkinase_Tyr 279-313 29 1.487165 2.5 Pfam 181-217 (270) Show / Hide 
Range on Protein: 279-313
Range on HMM: 181-217/270
Sequence Identity: 29% (11 aa)

LAPEILEDNDYGRAVDWWGTGVVMYEMMC-GRLP-FY
.||| . .. .  . | |  ||.|.|..  |. | ..
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYP
Pkinase_C AktA.AA Pkinase_C 393-444 30 1.2e-11 44.25 Pfam 1-46 (46) Show / Hide 
Range on Protein: 393-444
Range on HMM: 1-46/46
Sequence Identity: 30% (16 aa)

KVENETDTRYFDQEFTLEPVRLTPPAAGKDTLTATQHDEQSQFEKFSYTDDV
.|...|||..|| ||| ||...||    .. ... ...   .|. |.|. . 
QVKSPTDTSNFDPEFTDEPPMDTP--PDWR-MSSGDQE---PFRGFTYVNPD
S_TK_X AktA.AA S_TK_X 383-442 23 6e-06 27.13 SMART 7-79 (79) Show / Hide 
Range on Protein: 383-442
Range on HMM: 7-79/79
Sequence Identity: 23% (20 aa)

GLK-----VRPPFLPKVE----NETDTRYFDQEFTLEPVRLTPPAAGKDTLTATQHDE------QSQ----------FEKFSYTD
.|      . ||| ||.     ..|||..||.||| |...            .| .|.      . .          |. |.|  
KLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM------------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF