Gene PKCe (Sea Urchin)

PKCe

Species: Sea Urchin
Alias: Spk015, SPU_026498, SPU_027848, PKCe
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: AGC
Family: PKC
Subfamily: PKCh

Sequence

Name Sequence Type Origin Length Description Download
PKCe.AA Protein None 622 None Fasta, JSON
PKCe.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of PKCe.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C1_1 PKCe.AA C1_1 35-87 40 2.7e-21 81.82 Pfam 1-55 (55) Show / Hide 
Range on Protein: 35-87
Range on HMM: 1-55/55
Sequence Identity: 40% (22 aa)

HKFMST-FLRQPTFCSHCQDFIWG-LYRQGYQCQVCTVVVHKRCHEQIITRCPGH
|... . ...|||||.||..|.|| |..||..||.| ...|.|||..  . |...
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 PKCe.AA C1 35-84 30 5.3e-17 63.74 SMART 1-61 (61) Show / Hide 
Range on Protein: 35-84
Range on HMM: 1-61/61
Sequence Identity: 30% (19 aa)

HKFMSTFLRQPTFCSHCQDFIWGLYRQ-----GYQCQVCTVVVHKRCHEQIIT-------RC
|... .   .||.|.||...|||...|     ||.|..| ...||.||...          |
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
C1_3 PKCe.AA C1_3 58-77 33 0.256868 4.85 Pfam 10-30 (30) Show / Hide 
Range on Protein: 58-77
Range on HMM: 10-30/30
Sequence Identity: 33% (7 aa)

LYR-QGYQCQVCTVVVHKRCH
.||  .| |  |  ..|..| 
IYRDPFYHCMQCDFMLHEDCA
C1_1 PKCe.AA C1_1 107-159 45 3.8e-25 94.67 Pfam 1-55 (55) Show / Hide 
Range on Protein: 107-159
Range on HMM: 1-55/55
Sequence Identity: 45% (25 aa)

HRFSLH-NFRRPTFCDHCGSLLYG-LFKQGVQCEVCKMNVHKRCSRNVANNCGVN
|..  | ||..||||.|||....| |..||..|..|..|.|.||...|...|| |
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN
C1 PKCe.AA C1 107-156 32 2e-21 78.39 SMART 1-61 (61) Show / Hide 
Range on Protein: 107-156
Range on HMM: 1-61/61
Sequence Identity: 32% (20 aa)

HRFSLHNFRRPTFCDHCGSLLYGLFKQ-----GVQCEVCKMNVHKRCSRNVAN-------NC
|... ..| .||.|.||.....|.|||     |..|..||...||.|...|..       .|
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC
C1_3 PKCe.AA C1_3 137-149 30 0.012593 8.18 Pfam 18-30 (30) Show / Hide 
Range on Protein: 137-149
Range on HMM: 18-30/30
Sequence Identity: 30% (4 aa)

CEVCKMNVHKRCS
|  |  ..|..| 
CMQCDFMLHEDCA
Kinase PKCe.AA PKC 284-544 74 7.50000000001e-220 719.57 In-house 1-262 (262) Show / Hide 
Range on Protein: 284-544
Range on HMM: 1-262/262
Sequence Identity: 74% (196 aa)

FTFLKVLGKGSFGKVMLAERKGTDEVYAIKVLKKHAIIQDDDVECTMTEKRVLVLANRHPFLTSLHSCFQTKDRLFFVMEYVNGGDLMFQIQRARKFNEP
|.|||||||||||||||||||||||.||||||||..||||||||||||||||| ||..|||||.||.||||.|||||||||||||||||.||..|.|.|.
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RARFYAAEVTLALMFLHRHGVIYRDLKLDNILLDMDGHCKLADFGMCKEGILDGRTTATFCGTPDYIAPEILQELDYGPSVDWWALGVLMYEMMAGQPPF
.|||||||...||.|||..|.|||||||||.|||..||.|.||||||||....|.||.|||||||||||||||. .||.||||||.|||||||||||.||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

EADNEDDLFDSILHDDVLYPVWLSKEATSILKAFMTKNPSKRLGCMEAQ-GGERAILSHSFF
....||.||.||.||...||.||||||.||.|.||||||.|||||...| .||..| .| ||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase PKCe.AA Eta 284-544 87 2.2e-217 728.49 In-house 1-261 (261) Show / Hide 
Range on Protein: 284-544
Range on HMM: 1-261/261
Sequence Identity: 87% (229 aa)

FTFLKVLGKGSFGKVMLAERKGTDEVYAIKVLKKHAIIQDDDVECTMTEKRVLVLANRHPFLTSLHSCFQTKDRLFFVMEYVNGGDLMFQIQRARKFNEP
|.|.||||||||||||||||||||||||||||||..|||||||||||||||.|.||..|||||.||.||||||||||||||||||||||||||||||.||
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP

RARFYAAEVTLALMFLHRHGVIYRDLKLDNILLDMDGHCKLADFGMCKEGILDGRTTATFCGTPDYIAPEILQELDYGPSVDWWALGVLMYEMMAGQPPF
||||||||||.||||||.||||||||||||||||..|||||||||||||||..|.||.||||||||||||||||..|||||||||.||||||||.|||||
RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF

EADNEDDLFDSILHDDVLYPVWLSKEATSILKAFMTKNPSKRLGCMEAQGGERAILSHSFF
|||||||||.|||||||||||||.|||.|||||||||||.||||||.|||||.||..|.||
EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF
Kinase PKCe.AA AGC 284-544 36 8e-198 517.42 In-house 1-395 (395) Show / Hide 
Range on Protein: 284-544
Range on HMM: 1-395/395
Sequence Identity: 36% (144 aa)

FTFLKVLGKGSFGKVMLAERK------GTDEVYAIKVLKKHA-IIQDD--DVECTMTE------------KRVLVLANR---------HPFLTS-LHSCF
| ||||.||||||||.|...|      .|...||.|||||   |....  .||.||||            ...|...|          |||... ||..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTKDR--LFFVME----YVN-----GG-DLMFQIQ---RARKFNEPRARFYAAE-------VTLALMFLHR-HGVIYRD-LKLDNILLDMDGHCKLADFG
|.||.  |.||||    |||     || .|....|   . ..|.|.||||||||       ..||| .||. .|.|.|| ||..||||| |||.||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

MCKEGILDG--------------------------------------------------RTTATFCG--TPDYIAPEILQELDYGPSVDWWA--LGVLMY
.||||. ||                                                   .| ||||  ||.|.|||||    ||...|||.  ||.|||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMMAGQPPFEADN----------EDDLFDSIL------HDDVLYP----------VWLSKEATSILKAFMTKNPSKRLGCMEAQG---GERAILSHSFF
||..|.||| .||          ....|..|.      ...| .|          .|.|.|| ...| ...|.|.|||||..  .   |   | .| .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase PKCe.AA Alpha 284-544 67 1.3e-176 592.99 In-house 1-259 (259) Show / Hide 
Range on Protein: 284-544
Range on HMM: 1-259/259
Sequence Identity: 67% (175 aa)

FTFLKVLGKGSFGKVMLAERKGTDEVYAIKVLKKHAIIQDDDVECTMTEKRVLVLANRHPFLTSLHSCFQTKDRLFFVMEYVNGGDLMFQIQRARKFNEP
| ||.|||||||||||||||||||| ||||.|||  |||||||||||.||||| | .. |||...|||||| |||.||||||||||||..||.  || ||
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFKEP

RARFYAAEVTLALMFLHRHGVIYRDLKLDNILLDMDGHCKLADFGMCKEGILDGRTTATFCGTPDYIAPEILQELDYGPSVDWWALGVLMYEMMAGQPPF
 | |||||.  .| |||. |.|||||||||..|| .|| |.||||||||.. .. || |||||||||||||     || |||||| |||.||||||||||
HAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQPPF

EADNEDDLFDSILHDDVLYPVWLSKEATSILKAFMTKNPSKRLGCMEAQGGERAILSHSFF
. . ||.|| .|    | ||  .|||| .| |.|.||.|.|||||     ||. |  | ||
DGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPD--GEQDIREHPFF
Kinase PKCe.AA Delta 284-544 60 2.7e-143 482.34 In-house 1-259 (259) Show / Hide 
Range on Protein: 284-544
Range on HMM: 1-259/259
Sequence Identity: 60% (157 aa)

FTFLKVLGKGSFGKVMLAERKGTDEVYAIKVLKKHAIIQDDDVECTMTEKRVLVLANRHPFLTSLHSCFQTKDRLFFVMEYVNGGDLMFQIQRARKFNEP
|.|.||||||||||||||| ||... |||| |||  ...|||||||| |.||| || .||||. |   ||||. |||||||.||||||. ||  ..|.| 
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

RARFYAAEVTLALMFLHRHGVIYRDLKLDNILLDMDGHCKLADFGMCKEGILDGRTTATFCGTPDYIAPEILQELDYGPSVDWWALGVLMYEMMAGQPPF
||||||.|. ..| |||..|.|||||||||.|||.||| |.|||||||| ..   .. |||||||||||||..   |  |||||. |||||||. || ||
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF

EADNEDDLFDSILHDDVLYPVWLSKEATSILKAFMTKNPSKRLGCMEAQGGERAILSHSFF
. ..||.||.||..|   ||.|..|||...||. . ..| ||||  ..  |.  |  | ||
HGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGD--IRQHCFF
Kinase PKCe.AA Akt 284-544 50 6.7e-141 453.18 In-house 1-264 (264) Show / Hide 
Range on Protein: 284-544
Range on HMM: 1-264/264
Sequence Identity: 50% (134 aa)

FTFLKVLGKGSFGKVMLAERKGTDEVY-AIKVLKKHAIIQDDDVECTMTEKRVLVLANRHPFLTSLHSCFQTKDRLFFVMEYVNGGDLMFQIQRARKFNE
|.|||||||||||||.|.. | |...| |.|||||  ||| . || |.||...|.  | |||...||  |||.|.|.|||.|.|||.| . .||.|.|.|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN-HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

PRARFYAAEVTLALMFLHRHGVIYRD-LKLDNILLDMDGHCKLADFGMCKEG-ILDGRTTATFCGTPDYIAPEILQELDYGPSVDWWA-LGVLMYEMMAG
.|||||.||. ||. .|| ...|||| ||. |||.| ||| .|.|||.|||. | |. .| |||||| |.|||||.  ... .||||. ||..||||| |
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

QPPFEADNEDDLFDSILHDDVLYP--VWLSKEATSILKAFMTKNPSKRLGCMEAQGGERAILSHSFF
.||| ... . .|. |.  .| .|   |.|.|. ....   .|.|.||||   . .. . | .| .|
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLG--GGPNDAQEIKRHPWF
Kinase PKCe.AA SGK 284-544 44 1.2e-135 421.55 In-house 1-283 (283) Show / Hide 
Range on Protein: 284-544
Range on HMM: 1-283/283
Sequence Identity: 44% (126 aa)

FTFLKVLGKGSFGKVMLAERKGT------------------DEVYAIKVLKKHAII-------QDDDVECTMTEKRVLVLANRHPFLTSLHSCFQTKDRL
| ||||.||||||||.....|..                  | .||.|||.| .||       .   .  .|.|. |.    .|||. .||  ||||. |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FFVMEYVNGGDLMFQIQRARKFNEPRARFYAAEVTLALMFLHRHGVIYRDLKLDNILLDMDGHCKLADFGMCKEGILDGRTTATFCGTPDYIAPEILQEL
.|||.|||||.. . .||...| |.||||||||. .||  ||   .|||||| .||||| .|||.| ||| ||||| .  || |||||| | |||.|.  
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

DYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFDSILHDDVLYPVWLSKEATSILKAFMTKNPSKRLGCMEAQGGERAILSHSFF
 .. .|||| || ..|||| | |||.  |   ..| |.. .   |   | .| ....   .|.|.||||  .   . . | .| ||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKR---DFMEIKNHPFF
Kinase PKCe.AA Iota 284-544 55 3.3e-129 432.74 In-house 1-271 (271) Show / Hide 
Range on Protein: 284-544
Range on HMM: 1-271/271
Sequence Identity: 55% (151 aa)

FTFLKVLGKGSFGKVMLAERKGTDEVYAIKVLKKHAIIQDDDVECTMTEKRVLVLANRHPFLTSLHSCFQTKDRLFFVMEYVNGGDLMFQIQRARKFNEP
|  ..|.|.||. ||...| | |. .||.||.||  . .|.|..   ||| |   |  ||||  |||||||. |||||.|.|||||||| .|| ||  | 
FELIRVIGRGSYAKVLMVEHKKTRRIYAMKVIKKEMVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEFVNGGDLMFHMQRQRKLPEE

RARFYAAEVTLALMFLHRHGVIYRDLKLDNILLDMDGHCKLADFGMCKEGILDGRTTATFCGTPDYIAPEILQELDYGPSVDWWALGVLMYEMMAGQPPF
 ||||.||. ||| ||| .|.|||||||||.||| .|| || |.||||||| .| ||.|||||| |||||||   ||| |||||||||||.|||||  ||
HARFYSAEICLALNFLHERGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPF

---------EADNEDDLFDSILHDDVLYPVWLSKEATSILKAFMTKNPSKRLGCMEAQ-GGERAILSHSFF
         .   || ||  ||   .  |  ||  |...||.|. |.|  ||||      | . | .| ||
DIVGNMDNPDQNTEDYLFQVILEKQIRIPRSLSVRAAHVLKGFLNKDPKERLGCHPQTNEGFMDIKEHPFF
Kinase PKCe.AA PKN 284-544 52 3e-114 385.88 In-house 1-260 (260) Show / Hide 
Range on Protein: 284-544
Range on HMM: 1-260/260
Sequence Identity: 52% (139 aa)

FTFLKVLGKGSFGKVMLAERKGTDEVYAIKVLKKHAIIQDDDVECTMTEKRVLVLAN--RHPFLTSLHSCFQTKDRLFFVMEYVNGGDLMFQIQRARKFN
| .. |||.| ||||.|.. |.|.|.||||.|||. |.  |.||  |.|||..  .|  ||||| .|..||||..  .|||||. ||||| .|     |.
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHEDV-FS

EPRARFYAAEVTLALMFLHRHGVIYRDLKLDNILLDMDGHCKLADFGMCKEGILDGRTTATFCGTPDYIAPEILQELDYGPSVDWWALGVLMYEMMAGQP
||||.|||| | | | .||.| .|||||||||.||| .|. |.||||.||||.  |  |.||||||...|||.| .  |   |||| ||||.|||. | .
EPRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGEC

PFEADNEDDLFDSILHDDVLYPVWLSKEATSILKAFMTKNPSKRLGCMEAQGGERAILSHSFF
||  |.|...||.|. ||| || .|| || .|..  . ||| .|||  |    .  |  . ||
PFPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAED--IKMQPFF
Kinase PKCe.AA AktR 284-544 42 1.2e-110 373.87 In-house 1-268 (268) Show / Hide 
Range on Protein: 284-544
Range on HMM: 1-268/268
Sequence Identity: 42% (115 aa)

FTFLKVLGKGSFGKVMLAERK-GTDEVYAIKVLKKHAIIQDDDVECTMTEKRVLVLANRHPFLTSLHSCFQTKDRLFFVMEYVNGGDLMFQIQRARKFNE
|...|.|||| ||||.|...|  ....||.|..||. ||.    . | ||. ..   ..|||.  || |||||. |||.|||. ||.| . ... .||.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PRARFYAAEVTLALMFLHRH-GVIYRDLKLDNILLDMDGHCKLADFGMCK-EGIL-DGRTTATFCGTPDYIAPEILQE-LDYGPSVDWWALGVLMYEMMA
 .||||.|.. ||| .|| |  .|||||| .|||||.||| |..|||. | ...  .  .. .||||| |.|||....   .. ||||||.|.. |||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GQPPFEADNEDDLFDSILHDD---VLYPVWLSKEATSILK-AFMTKNPSKRLG--CMEAQGGERAILSHSFF
|.|||...|  ..|..|.  .   . ||. .|... ....   . ||| ||||  |. ..     | || .|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWE----EIKSHPWF
Kinase PKCe.AA S_TKc 284-544 36 3.8e-104 353.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 284-544
Range on HMM: 1-231/231
Sequence Identity: 36% (98 aa)

FTFLKVLGKGSFGKVMLAERKGTDEVYAIKVLKKHAIIQDDDVECTMTEKRVLVLANRHPFLTSLHSCFQTKDRLFFVMEYVNG--GDLMFQIQRARK--
...|...|||.||||...  |.|....|||..|          | .. | ..|    .||..  |. .||. |.|..||||..|  |||.  |.. ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FNEPRARFYAAEVTLALMFLHRHGVIYRDLKLDNILLDMDGHCKLADFGMCKEGILDGRTTATFCGTPDYIAPEILQELDYGP-SVDWWALGVLMY
    |.| .||||.... .|| ..|.||.|.|||| .|||||   | |..|||....         ||||||.|.|||.|    ||. ..|||..|...|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EMMAGQPPFEADNEDDLFDSILHDDVLYPVWLSKEATSILKAFMTKNPSKRLGCMEAQGGERAILSHSFF
||..|.|||.  ... .|. |.          |.|| ....  ..|.|.||... ||  .|..| .| .|
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PKCe.AA Pkinase 284-544 29 6.9e-84 289.8 Pfam 1-293 (293) Show / Hide 
Range on Protein: 284-544
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

FTFLKVLGKGSFGKVMLAERKGTDEVYAIKVLKKHAIIQDDDVECTM-TEKRVLVLANRHPFLTSLHSCFQTKDRLFFVMEYVNGG----DLMFQIQ--R
.......|.||||.| .. .||| ...|.|..||. .  . |.. .  .| ...    .||.   |. .|..||.. .||||..||    ||.  |.  |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

ARKF--NEPRARFYAAEVTLALMFLHRHGVIYRDLKLDNILLDMDGHC----KLADFGMCKEG-ILDGRTTATFCGTPDYIAPEILQ-ELDYGPSVDWWA
 ..|   |  ..||. ..  .| ..|..|.|.||||..|||.| .||.    |..||| .|   .  .. . ||||||.|.|||...   .|||.||.|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVLMYEMMAGQPPFEAD------NEDDLFDSILHDDVLYPVWLS---------------------KEATSILKAFMTKNPSKRLGCMEAQGGERAILSH
.|...|||. |.|||  .      ... ... |.. .. .. . .                     .|. ...|   .|.|.||..        . || |
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-------AEQILQH

SFF
 .|
PWF
Kinase PKCe.AA S_TK_X 545-608 41 8.8e-24 86.25 SMART 1-79 (79) Show / Hide 
Range on Protein: 545-608
Range on HMM: 1-79/79
Sequence Identity: 41% (33 aa)

REIHWQELEE--LKVEPPFKPKIK----TKKDWNNFDTDFTREEPKLTPITTKIVESINQNE---------FSGFTYTR
|.| |. |.    ..|||||||||       | .|||..||.|.|.|||. . ...|..|||         | |||| .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase PKCe.AA TyrKc 284-539 20 1.5e-15 28.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 284-539
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

FTFLKVLGKGSFGKVMLAERKGTDEVYAIKVLKKHAIIQDDDVECTMTEKRVLVLA-NRHPFLTSLHSCFQTK-------DRLFFVMEYVNGGDLMFQIQ
 |..|.|| | ||.|.... |   .  |.|.||..|      .|  | | |..     .|| .  |. .  ..       . |. ||||. .|||   ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RARK-FNEPRARFYAAEVTLALMFLHRHGVIYRDLKLDNILLDMDGHCKLADFGMCKEGILD-------GRTTATFCGTPD------YIAPEILQELDYG
. |. .. .    ..  .     .||....| |||   |.|.. ....| .|||.....  |          ...  .  .        ||| ...  . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PSVDWWALGVLMYEMMA-GQPPFEA-----DNEDDLFDSILHDDVLYPVWL---------SKEATSILKAFMTKNPSKRLGCMEAQGGERAIL
.  | |. ||.|.|..  ||.| .       . ....  . . . . .            ..|  .| |     .|..|    |     . ..
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI----HECF
Kinase PKCe.AA Pkinase_C 564-610 40 7.4e-15 55.53 Pfam 1-46 (46) Show / Hide 
Range on Protein: 564-610
Range on HMM: 1-46/46
Sequence Identity: 40% (19 aa)

KIKTKKDWNNFDTDFTREEPKLTPITTKIVESINQNEFSGFTYTRPT
..| . |  |||..||.| |..|| ..    |..|..| ||||..| 
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
Kinase PKCe.AA Pkinase_Tyr 284-442 23 6.8e-14 47.67 Pfam 1-171 (270) Show / Hide 
Range on Protein: 284-442
Range on HMM: 1-171/270
Sequence Identity: 23% (41 aa)

FTFLKVLGKGSFGKVMLAERK----GTDEVYAIKVLKKHAIIQD---DDVECTMTEKRVLVLANRHPFLTSLHSCFQ-TKDR--LFFVMEYVNGGDLMFQ
 ||.|.||.|.||.|.... |    .|.   |.|.|| .|  ..   .|    | | ...    .|| . .|. .    ..   .. ||||. .|||   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDF---MREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

IQR----ARKFNEPRARFYAAEVTLALMFLHRHGVIYRDLKLDNILLDMDGHCKLADFGMCKEGILDGRT-TAT
 ..     .... ..   .....  .. .|.... | |||   |.|.. ....| .|||...    |.   ...
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKR
Kinase PKCe.AA Pkinase_Tyr 467-484 40 0.585949 3.87 Pfam 198-217 (270) Show / Hide 
Range on Protein: 467-484
Range on HMM: 198-217/270
Sequence Identity: 40% (8 aa)

WALGVLMYEMMA-GQPP-FE
|. ||||.|..  |. | ..
WSFGVLMWEIFTYGEQPTYP