BCKDK

Species: Sea Urchin
Alias: Spk042, SPU_025160, BCKDK
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Atypical
Family: PDHK
Subfamily: BCKDK

Sequence

Name Sequence Type Origin Length Description Download
BCKDK.AA Protein None 489 None Fasta, JSON

Protein domain

Protein domains of BCKDK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
BCDHK_Adom3 BCKDK.AA BCDHK_Adom3 73-228 28 2e-63 219.84 Pfam 1-199 (199) Show / Hide
Range on Protein: 73-228
Range on HMM: 1-199/199
Sequence Identity: 28% (57 aa)

VRLTPATLLYTGK-SPDGNHLLRSAQYLHKELPVRVAHRIAEFRGLPFIVGCNPTILHVHELYIRAFHLLSE-F--------------PSIRDMDT----
 .|. . ... |.  |  ..|..|||..|.|||.| |||| |.. ||... ..| |..|...|...|. | | |              | ......    
TPLSLRQMMQFGRPNPCEKTLFKSAQFCHEELPIRLAHRIRELQNLPYGLNKMPHIQQVYNWYYQSFEELRECFPKPISELKHLRYYEPPPKTLEDWLHD

-ERQYCKMVKTLLDDHK-DVVTHLAEGFRECR-KHI----TDES----LIHNFLDRILTSRLGI---RMLAEHHLFL-----HQDK----NDSIGIIAT
 ....|.|.....|.|  .||...|.|..|.. ...     ...     |. |||| ..|| ||   |||...|. |     |. .    .| .||| |
YNEKFCDMLRDIKDRHDRNVVPTMAQGVLEWKCRYYGQDNQPDDLHWFQIQYFLDRFYMSRIGINFIRMLIGQHIALFEFNYHNPHHFEHPDYVGIICT

Kinase BCKDK.AA PDHK 389-480 36 1.9e-32 109.56 In-house 50-140 (140) Show / Hide
Range on Protein: 389-480
Range on HMM: 50-140/140
Sequence Identity: 36% (35 aa)

ISDRGGGIPHSLLKKVFQYHFTTAND---DESVSDNGGALGTMIEAVNQPT-AGPLCGFGFGLPVSKAYAEYLGGSISLETMQGIGTDVYLRLRHI
.||||||.||  .  .| |...||     | ..|   | |      . ... |.|. |||.|||.. .||.|..|.  |  |.|.|||....|. .
MSDRGGGVPHRKIDRLFNYMYSTAPRSTQDPRMSPLFGHL-----DMHETSRAAPMHGFGYGLPICRLYAKYFQGDLQLYSMEGYGTDAVIYLKAL

Kinase BCKDK.AA PDHK 269-316 45 3.3e-24 80.87 In-house 1-48 (140) Show / Hide
Range on Protein: 269-316
Range on HMM: 1-48/140
Sequence Identity: 45% (22 aa)

YIIQPLDYMLPELLKNAMRATIESHLDTPMNLPDVVITIASNEVDFII
|.  .|..||.||.|||||||.|.|.|.| |.|......| ...| .|
YVPMHLYHMLFELFKNAMRATMEHHEDRPYNYPPIKVMVALGDEDLTI

Kinase BCKDK.AA HATPase_c 389-480 21 2.3e-10 38.33 Pfam 42-120 (120) Show / Hide
Range on Protein: 389-480
Range on HMM: 42-120/120
Sequence Identity: 21% (21 aa)

ISDRGGGIPH------SLLKKVFQYHFTTANDDESVSDNGGALGTMIEAVNQPTAGPLCG--FGFGLPVSKAYAEYLGGSISLETMQGIGTDVYLRLRHI
..| | |||        .. ..|. ...| .|                     .     |  .|.|| ......| .||.|..|.  | || . ..|   
VEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPD--------------------SR-RKYGGGLTGLGLYICRRIVEQHGGTIWVESEPGGGTTFTFTLPLE





Kinase BCKDK.AA PDHK 437-480 45 3.3e-10 33.76 In-house 82-125 (125) Show / Hide
Range on Protein: 437-480
Range on HMM: 82-125/125
Sequence Identity: 45% (20 aa)

AGPLCGFGFGLPVSKAYAEYLGGSISLETMQGIGTDVYLRLRHI
| || |||.|||... || |  | . |  |.| |||  . |. .
AAPLAGFGYGLPICRLYAKYFQGDLKLYSMEGYGTDAVIYLKAL

Kinase BCKDK.AA PDHK 328-358 45 1.3e-09 30.15 In-house 43-73 (140) Show / Hide
Range on Protein: 328-358
Range on HMM: 43-73/140
Sequence Identity: 45% (14 aa)

DNDVLNRISDRGGGIPHSLLKKVFQYHFTTA
| |   ..||||||.||  .  .| |...||
DEDLTIKMSDRGGGVPHRKIDRLFNYMYSTA

Kinase BCKDK.AA PDHK 269-308 40 3.7e-07 22.74 In-house 1-39 (125) Show / Hide
Range on Protein: 269-308
Range on HMM: 1-39/125
Sequence Identity: 40% (16 aa)

YIIQPLDYMLPELLKNAMRATIESHLDTPMNLPDVVITIA
|.   |  || || |||||||.|.| . .  .| . . ..
YVPSHLYHMLFELFKNAMRATVEHHENRK-IYPPIKVMVT

Kinase BCKDK.AA HATPase_c 269-481 13 2.5e-05 24.96 SMART 1-130 (130) Show / Hide
Range on Protein: 269-481
Range on HMM: 1-130/130
Sequence Identity: 13% (31 aa)

YIIQPLDYMLPELLKNAMRATIESHLD---TPMNLPDVVITIASNEVDFIISFGWQNQLIEYDNDVLNRISDRGGGIPHSLLKKVFQYHFTTANDDESVS
    .|  .| .||.|| ..| |.| |   .. . ..  ||.  .                                                       
GDPDRLRQVLWNLLDNAIKHTPEGHADPDLHDGKPGGGRITVRVH-------------------------------------------------------

DNGGALGTMIEAVNQPTAGPLCGISDRGGGIPH------SLLKKVFQYHFTTANDDESVSDNGGALGTMIEAVNQPTAGPLCG--FGFGLPVSKAYAEYL
                       ..| | |||        .....|.  ..|.. ..                .. ..    |  .| ||...|...| .
--------------------RITVEDNGPGIPPEMHKSIEDIPRIFEPFYRTDDSPS-------------RMCPDSRSRKYGGGLTGLGLSICKRIVEQH

GGSISLETMQGIGTDVYLRLRHID
||.|..|      | ....|.   
GGTIWVE------TTFTFTLPLER

Kinase BCKDK.AA HATPase_c 269-368 13 8.9e-05 18.87 Pfam 1-84 (120) Show / Hide
Range on Protein: 269-368
Range on HMM: 1-84/120
Sequence Identity: 13% (15 aa)

YIIQPLDYMLPELLKNAMRATIESHLDTPMNLPDVVITIASNEVDFIISFGWQNQLIEYDNDVLNRISDRGGGIPH------SLLKKVFQYHFTTAN--D
    .|  .. .|. ||...| |.        . . ...   .                 ..|  ...| | |||        .. ..|. ...| .  .
GDPDRLHQVVWNLVDNAIKHTPEG--------GHITVRVHRDD-----------------DHVRITVEDNGPGIPPEMHSIAEDIPRIFEPFYRTDPDSR

DESVSD--NG
 ....   .|
-RKYGGGLTG

Kinase BCKDK.AA PDHK 334-358 44 0.000709 10.9 In-house 48-72 (125) Show / Hide
Range on Protein: 334-358
Range on HMM: 48-72/125
Sequence Identity: 44% (11 aa)

RISDRGGGIPHSLLKKVFQYHFTTA
..||||||.|   . . | | . ||
KMSDRGGGVPLRKIDRLFNYMYSTA

Kinase BCKDK.AA PDHK 389-412 45 0.000892 10.54 In-house 49-72 (125) Show / Hide
Range on Protein: 389-412
Range on HMM: 49-72/125
Sequence Identity: 45% (11 aa)

ISDRGGGIPHSLLKKVFQYHFTTA
.||||||.|   . . | | . ||
MSDRGGGVPLRKIDRLFNYMYSTA