Gene Chk1 (Sea Urchin)

Chk1

Species: Sea Urchin
Alias: Spk099, Chk1, SPU_007530
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CHK1

Sequence

Name Sequence Type Origin Length Description Download
Chk1.AA Protein None 463 None Fasta, JSON
Chk1.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of Chk1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Chk1.AA CHK1 9-265 55 1.2e-187 629.67 In-house 1-276 (276) Show / Hide 
Range on Protein: 9-265
Range on HMM: 1-276/276
Sequence Identity: 55% (154 aa)

WDFVQTLGEGAYGEVKLAVN-RSTQEAVAVKILHLDKQQ--GAADS-VRKEVCIHRMLG----DPHIIRFYGHRKEGSIQYLFVEYASGGELFDRIEPDV
...||||||||.|.|||..| |...||||.|. |...|.  ...|. .|||.||..||.    ....||..|.|......|||.|||.||.|||.||||.
YEVVQTLGEGAFGQVKLCENQRNPEEAVAMKEIHIKGQHKMCFMDNDIRKEYCIQKMLSKIGKHENVIRMMGMRMDPEFYYLFMEYADGGDLFDKIEPDC

GMQVTEAHRFFSQLIGGVEYLHKKG-VTHRDLKPENLLLDEHD------NLKVSDFGLATVFR-HQGKERLLGKCCGTPPYVAPEVLKRKEYHAEPADVW
||...||||.|.||| |..|.|..| |||||.||||||||.||      |||..||||||..| |.|.||.| |.||||||.||||...|.|...|.|.|
GMPSDEAHRYFKQLISGLKYIHCCGGVTHRDIKPENLLLDKHDSNDMPDNLKIADFGLATWYRRHDGEERMLDKRCGTPPYMAPEVCTGKQYRGPPVDIW

SCGIILVAMLAGELPWDEPT-YSCKEYCDWLDKK--MHLSPWKKIDTTPLALLRKILTETPAKRITISQIKKDRWY
|||..|.|||.||||||.|. ..|.|||.| |.|  ||..||.|||.....||||||.|.|.||.||.||.||.||
SCGVVLMAMLTGELPWDQPSHMDCQEYCWWMDNKHWMHWCPWSKIDCRAICLLRKILCENPNKRATIEQIEKDPWY
Kinase Chk1.AA CAMKL 9-265 35 1.2e-131 422.41 In-house 1-297 (297) Show / Hide 
Range on Protein: 9-265
Range on HMM: 1-297/297
Sequence Identity: 35% (107 aa)

WDFVQTLGEGAYGEVKLAVN-RSTQEAVAVKILHLDKQQ--GAADS------------VRKEVCIHRMLG---DPHIIRFYGHRKEGSI------QYLFV
.....|||.|..|.||||.. | |.| ||.||.. .| .    ...            .|.|..|..||     |.||..| ..   .        ||. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYASGGE--LFDRI--EPDVG--MQVTEAHRFFSQLIGGVEYLHKKGVTHRDLKPENLLLDEHD--NLKVSDFGLATVFR-H-QGKERLLGKCCGTPPYV
||.||||  |||.|  .....  |.  ||.|.| |.. .|.|.|..|. |||.||||.||||..  |.|..|||... .| .  |....|  .||.||| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVLKR--KEYHAEPADVWSCGIILVAMLAGELPWDEPTY-----SCKEYCDWLDKK-MHLSPWKKIDTTPLALLRKILTETPAKRITISQIKKDRWY
|||....  |.|.. ..|.||||.|| ||. |.||.|..||     ... |  | ...  .  .|....     |.||.|.  | ||.|| ||....|.
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCGYYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase Chk1.AA CAMK 14-265 23 1e-101 328.57 In-house 1-425 (425) Show / Hide 
Range on Protein: 14-265
Range on HMM: 1-425/425
Sequence Identity: 23% (98 aa)

TLGEGAYGEVKLAVNRSTQ------------EAVAVKILHLDKQQG---------------------------AADSVRKEVCIHRMLG-------DPHI
|||.|..|.|||.....|.            . ||.||.  .| ..                             ..||.|..|...|         |.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRFYGHRKEGSI-------------------QYLFV---EYASGGEL----FDRI--EPD-------------VGMQVTEAHRFFSQLIGGVEYLHKKGV
|..| .   ..                     |..    ||.|||||    ||.|   ..               ..  ||.|.| |.. .|.|.|....
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

THRDLKPENLLLDEHD-----------------NLKVSDFGLATVFRHQGKER---------------------LLGKCCGTPPYVA-PEVLKR------
 ||||||||.|||...                 |.|..|||.|..|..  ...                     ..  .||||.|.| ||||..      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KEYHAEPADVWSCGIILVAMLAGELPWDEP-----------------TYSCKEYCDWLDKKMHLSP---------WKKIDTT--------PLA
       |.|. ...|.||||.|| .|| |..|....                 ..     ...     ..||         |..|              
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LLRKILTETPAKRITISQIKKDRWY
|.||.|.  | ||.||.|.... |.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Chk1.AA S_TKc 9-265 29 1.7e-87 297.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-265
Range on HMM: 1-231/231
Sequence Identity: 29% (80 aa)

WDFVQTLGEGAYGEVKLAVNRSTQEAVAVKILHLDKQQGAADSVRKEVCIHRMLGDPHIIRFYGHRKEGSIQYLFVEYASG--GELFDRIEPDVG-----
.......|.||.|.|.......|.. ||.||..        ...|.|. |... . |.|...|..  . .  |.. ||..|  |.|||.|.   .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-MQVTEAHRFFSQLIGGVEYLHKKGVTHRDLKPENLLLDEHDNLKVSDFGLATVFRHQGKERLLGKCCGTPPYVAPEVLKRKEYHAEPADVWSCGIILVA
 .   .| ... |.. ..||.|..|. ||||||||.||||  ..|..|||||...           .|||| |.|||||    |  ...|.||||.||  
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLAGELPWDEPTYSCKEYCDWLDKKMHLSPWKKIDTTPLALLRKILTETPAKRITISQIKK-------DRWY
||.|. |..       ..   ..| .        .   . ..||.|.  |.||.|. .. .       . | 
MLCGYPPFP-------QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Chk1.AA AMPK 9-211 42 1.6e-77 229.76 In-house 1-203 (254) Show / Hide 
Range on Protein: 9-211
Range on HMM: 1-203/254
Sequence Identity: 42% (87 aa)

WDFVQTLGEGAYGEVKLAVNRSTQEAVAVKILHLDKQQGAADS--VRKEVCIHRMLGDPHIIRFYGHR-KEGSIQYLFVEYASGGELFDRIEPDVGMQVT
    .|.|||..| ||...   |.|.||.|||  .| .. ...  ...|. | ...  ||||. |    .  .  ....||.||||||| |     .|  
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EAHRFFSQLIGGVEYLHKKGVTHRDLKPENLLLDEHDNLKVSDFGLATVFRHQGKERLLGKCCGTPPYVAPEVLKRKEYHAEPADVWSCGIILVAMLAGE
|| ||| | | ||||.|. .. ||||||||||||.. |.|. ||||  .     .  .|  .|| | | |||.   | |     |.||||.|| ||| | 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMK---DGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGY

LPWDEP
|| |..
LPFDDE
Kinase Chk1.AA Pkinase 9-265 27 5.9e-72 250.16 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-265
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

WDFVQTLGEGAYGEVKLAVNRSTQEAVAVKILHLDKQQGAAD-SVRK--EVCIHRMLGDPHIIRFYGHRKEGSIQYLFVEYASGG----ELFDRIE--PD
. .....|.|..|.|.......|.. |||||. ....    | . |.  |..|...|. |.|.|.|.   ...  |.  ||. ||    .|||.|.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VGM--QVTEAHRFFSQLIGGVEYLHKKGVTHRDLKPENLLLDEHDNL----KVSDFGLATVFRHQGKERLLGKCCGTPPYVAPEVLKRKEYHAEPADVWS
 ..  .  |. ... |.. |.||.|..|. ||||||||.|.|.....    |..||||| .|.   . . .   ||||.|.||||..  .|.  ..|.||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

CGIILVAMLAGELPWDEP----TYSCKEYCDWLDKK--MHLSPWKKID-------------------TTPLALLRKILTETPAKRITISQIKKDRWY
||.||  || |..|...     .  .. ..  ....   | . .....                    . . .....|.  |.||.|. ||... | 
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase Chk1.AA MARK 9-217 37 1e-69 227.08 In-house 1-215 (262) Show / Hide 
Range on Protein: 9-217
Range on HMM: 1-215/262
Sequence Identity: 37% (81 aa)

WDFVQTLGEGAYGEVKLAVNRSTQEAVAVKILHLDKQQG--AADSVRKEVCIHRMLGDPHIIRFYGHRK--EGSI-QYLFVEYASGGELFDRIEPD--VG
  ...|.|.|.|..||||... |.. ||.||.   | .   .  .|. |. |...|  |.||...      . .   ||  ||||||||.|.|.      
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

MQVTEAHRFFSQLIGGVEYLHKKGVTHRDLKPENLLLDEHD--NLKVSDFGLATVFRHQGKERLLGKCCGTPPYVAPEVLKRKEYHAEPADVWSCGIILV
..  ||.|.|.|.. .|.|.|.|.. |||.||||.|.||.   | | .|||... .     ...|  .|||||| |||....|.| . ..|.||.|..| 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIP---PGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLY

AMLAGELPWDEPTYSCKE
.|. | .|.|. |.. ||
FMVCGYFPFDGDTQDYKE
Kinase Chk1.AA Ciliate-E2 9-265 22 8.5e-56 190.01 In-house 1-365 (365) Show / Hide 
Range on Protein: 9-265
Range on HMM: 1-365/365
Sequence Identity: 22% (87 aa)

WDFVQTLGEGAYGEVKLAVNRSTQEA-----------------------VAVKILHLD--KQQGAADSVRKEVC----------IHRMLGDPHIIRFYGH
 .|.. .|.|..| |... ....|.                        .|.||.. .  .|.   ... .|.           | . |  |.||..| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

RK---EGSIQYLFVEYASGGELFDRIE------------PDVGMQVTEAHRFFSQLIG---------------GVEYLHKKG-VTHRDLKPENLLLDEHD
 .   . .| ||  ||..||.|||.|.                .   |. ... |..                ..||||.|. . |||.||||.|.    
FQEKDDNNI-YLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

NLKVSDFGLAT------------------VFRHQGKERLLGKC------------CGTPPYVAPEVLKRKEY--------HAEPADVWSCGIILVAMLAG
 .|..||||..                   | .. ..|  |.             ||||.|.|||.|..|.|        . . .|.||.|.||  || |
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

ELPWDEPTYSCKEYCDWLDKKMHLS----------------PWKKIDTTPLALLRK----ILTETPAKRIT-ISQIKKDRWY
..|.         .   ...|  ..                 |||..     |..|    .|   | |||| ..||..  | 
KPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase Chk1.AA QIK 9-212 37 4.9e-55 189.16 In-house 1-222 (272) Show / Hide 
Range on Protein: 9-212
Range on HMM: 1-222/272
Sequence Identity: 37% (85 aa)

WDFVQTLGEGAYGEVKLAVNRSTQEAVAVKILHLDKQQGAADSVRK---EVCIHRMLGDPHIIRFYGHRKEGSIQYLFVEYASGGELFDRIEP-------
 |  .|.| | .. |||| .| | . ||.||  .|| |  ..   |   || |  ||  ||||. |      .  |.  ||.|.||.|| .         
YDIERTIGKGNFAVVKLARHRITKTKVAIKI--IDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVK

-------------DVGMQVTEAHRFFSQLIGGVEYLHKKGVTHRDLKPENLLLDEHDNLKVSDFGLATVFRHQGKERLLGKCCGTPPYVAPEVLKRKEYH
              | |.  || | |.|.. .|.|.||... ||||| ||.|||.  | |. |||.     .. .. ||  .||.||| |||... ||| 
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSN---WFKQGQLLMTWCGSPPYAAPEMFEGKEYD

AEPADVWSCGIILVAMLAGELPWDEPT
   .|.|| |..| .. .| || | .|
GPKVDIWSMGVVLYVLVCGALPFDGKT
Kinase Chk1.AA GIN4 52-265 37 5.4e-51 160.91 In-house 81-293 (293) Show / Hide 
Range on Protein: 52-265
Range on HMM: 81-293/293
Sequence Identity: 37% (81 aa)

VRKEVCIHRMLGDPHIIRFYGHRKEGSIQYLFVEYASGGELFDRIEPDVGMQVTEAHRFFSQLIGGVEYLHKKGVTHRDLKPENLLLDEHDN-LKVSDFG
. .|. | ...  | ..| |    . .  || .||| .||||. .     .   || ..| |.| || | |  .. ||||||||||||.  | .|. |||
IEREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFG

LATVFRHQGKERLLGKCCGTPPYVAPEVLKRKEYHAEPADVWSCGIILVAMLAGELPWDEPTYSCKEYCDWLDKKMHLSPWK-KIDTTPLALLRKILTET
.| .   . .. ||   || | | |||.     ||  ..||||||.|| |.| | ||.||     ..      |  .  |   .|      |.||||.  
MAAL---ETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVD

PAKRITISQIKKDRWY
| |||.. .| |    
PEKRIKTRDILKHPLI
Kinase Chk1.AA BRSK 9-209 40 1.4e-49 167.11 In-house 1-201 (254) Show / Hide 
Range on Protein: 9-209
Range on HMM: 1-201/254
Sequence Identity: 40% (83 aa)

WDFVQTLGEGAYGEVKLAVNRSTQEAVAVKILHLDKQQ---GAADSVRKEVCIHRMLGDPHIIRFYGHRKEGSIQYLFVEYASGGELFDRIEPDVGMQVT
.    ||| |  | ||| |   | . ||.||    |          |  |. | ..   ||... |         ||  |. |||||||      ...  
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

EAHRFFSQLIGGVEYLHKKGVTHRDLKPENLLLDEHDNLKVSDFGLATVFRHQGKERLLGKCCGTPPYVAPEVLKRKEYHAEPADVWSCGIILVAMLAGE
|| .|| | | .... | . . |||||||||||||  | |. |||.| .   | |. .|   || | |  ||| .  .|    |||||||.|| |.| | 
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASL---QVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGA

LPWD
|| |
LPFD
Kinase Chk1.AA CAMK1 113-198 46 3.6e-40 114.41 In-house 116-206 (276) Show / Hide 
Range on Protein: 113-198
Range on HMM: 116-206/276
Sequence Identity: 46% (44 aa)

QLIGGVEYLHKKGVTHRDLKPENLLL---DEHDNLK--VSDFGLATVFRHQ-GKERLLGKCCGTPPYVAPEVLKRK--EYHAEPADVWSCGIIL
|... |||.|.||. ||||||||||.   ||.  .|  ..||||.. | |. .   |. ..|||| |||||||..|  . .  . |.||.|.|.
QILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDEN---LMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVIT
Kinase Chk1.AA CAMK1 9-96 28 1.2e-20 56.67 In-house 1-99 (276) Show / Hide 
Range on Protein: 9-96
Range on HMM: 1-99/276
Sequence Identity: 28% (28 aa)

WDFVQTLGEGAYGEVKLAVNRST---QEAVAVKILH-LDKQQGAA----DSVRKEVCIHR---MLGDPHIIRFYGHRKEGSIQYLFVEYASGGELFDRI
  |  ..|.|| .||.|.....|   ....|.|..   .  ..      .....|. |..    .  |.|| || .  . .  || .|. .||||||||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRI
Kinase Chk1.AA TyrKc 9-264 23 3.6e-15 22.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-264
Range on HMM: 1-280/280
Sequence Identity: 23% (67 aa)

WDFVQTLGEGAYGEVKLAVNRSTQEAVAVKILHLDKQQGAADSVRKEVCIHRML--GDPHIIRFYGHRKEG-------SIQYLFVEYASGGELFDRI-EP
  . ..|||||.||| ... .   . |||| |. |.        ..|  | ..|    |.|.|.||   ..          .. .||...| | |.. ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

DVGMQVTEAHRFFSQLIGGVEYLHKKGVTHRDLKPENLLLDEHDNLKVSDFGLATVFRHQ---GKERLLGKC----CGT--PPY--VAPEVLKRKEYHAE
    .. . . |  |   | ||||.|.. ||||   | |..|    |.|||||.    .    | .    .     .|    |.   |||... ...  .
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

PADVWSCGIIL--VAMLAGELPWDEPT--YSCKEYCDWLDKKMHLSPWKK--------IDTTPLALLRKILTETPAKRITISQIKKDRW
  |||| |. .  .  . .. ....     | .|   .... . . . .           .    . ..   | |..| | |.| ....
-SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase Chk1.AA AMPK 241-265 40 3.3e-09 23.55 In-house 230-254 (254) Show / Hide 
Range on Protein: 241-265
Range on HMM: 230-254/254
Sequence Identity: 40% (10 aa)

LLRKILTETPAKRITISQIKKDRWY
|....|.  | |||||..|... |.
LIKHMLQVDPMKRITIHDIRNHPWF
Kinase Chk1.AA GIN4 9-40 43 3.1e-07 18.7 In-house 1-32 (293) Show / Hide 
Range on Protein: 9-40
Range on HMM: 1-32/293
Sequence Identity: 43% (14 aa)

WDFVQTLGEGAYGEVKLAVNRSTQEAVAVKIL
|   .||| |. | |.|| | .| .  |||..
WKLGETLGFGSTGKVQLAKNMETGQRAAVKVI
Kinase Chk1.AA BRSK 241-265 44 3.3e-07 20.6 In-house 230-254 (254) Show / Hide 
Range on Protein: 241-265
Range on HMM: 230-254/254
Sequence Identity: 44% (11 aa)

LLRKILTETPAKRITISQIKKDRWY
|||. ..  |.|||....|.|  ||
LLRGMIEVDPDKRISLKEIQKHPWY
Kinase Chk1.AA MARK 241-265 40 6.9e-07 18.73 In-house 238-262 (262) Show / Hide 
Range on Protein: 241-265
Range on HMM: 238-262/262
Sequence Identity: 40% (10 aa)

LLRKILTETPAKRITISQIKKDRWY
|....||  | .|.||..| |..| 
LIQRLLTVNPEERPTIEEIMKHPWM
Kinase Chk1.AA Pkinase_Tyr 117-152 50 3.3e-05 18.25 Pfam 123-158 (270) Show / Hide 
Range on Protein: 117-152
Range on HMM: 123-158/270
Sequence Identity: 50% (18 aa)

GVEYLHKKGVTHRDLKPENLLLDEHDNLKVSDFGLA
| |||. |.  ||||   | |..|    |..|||||
GMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase Chk1.AA QIK 241-265 44 4.5e-05 16.02 In-house 248-272 (272) Show / Hide 
Range on Protein: 241-265
Range on HMM: 248-272/272
Sequence Identity: 44% (11 aa)

LLRKILTETPAKRITISQIKKDRWY
| |. |.  |..|.|| ||.. || 
LIRHMLVVDPEHRYTIMQICQHRWM
Kinase Chk1.AA Pkinase_Tyr 9-92 30 0.000121 16.35 Pfam 1-94 (270) Show / Hide 
Range on Protein: 9-92
Range on HMM: 1-94/270
Sequence Identity: 30% (29 aa)

WDFVQTLGEGAYGEVKLAVNR----STQEAVAVKILHLDKQQGAA---DSVRKEVCIHRML-GDPHIIRFYGHRK-EGSI--QYLFVEYASGGEL
  | ..|||||.|||.... .    .|.  ||||.|  ..    .   ..  .|. | . |   |.|.|.||    .|     |. .||. .| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL
Kinase Chk1.AA CAMK1 241-265 28 0.00171 5.95 In-house 252-276 (276) Show / Hide 
Range on Protein: 241-265
Range on HMM: 252-276/276
Sequence Identity: 28% (7 aa)

LLRKILTETPAKRITISQIKKDRWY
.... |.  | ||.|..|. ...| 
FIKHMLEVDPKKRYTCEQCLNHPWI