Gene HUNKb (Sea Urchin)
HUNKb
Sequence
Protein domains of HUNKb.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | HUNKb.AA | CAMKL | 89-343 | 40 | 3.8e-137 | 440.31 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 89-343 Range on HMM: 1-297/297 Sequence Identity: 40% (122 aa) YILGDVIGEGSFAKVRLGTH-ILTQEQVAVKVIDKKLIANRDYVRKN-----------LRREATVLQKMR---HTNIARLYEVLETASN------YYLVM |..|...|.|||.||.|.|| ..|.|.||.|.|||| | |.....|| .|||. ..... | || .||||.|| .. .|||| YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELAEGGT--FMSFLCKR----RKLSERETRRYIRQLVTAVDHMHHLDVIHRDIKIENFLLDNDQ--NLKVIDFGLSNILG-Y----DGFLRTQCGSPAYA |...|| . ...|. ....|.|.||| ||.| ||...| ....||||| || |||... |.|.||||.||. . . .|.|.||||.|. EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM APEIFCN---SSYGPSVDVWSIGVNMYAMLTGELPFVVDPPN-----NMSKLHARIMQGATIPD---TLTKDCRDLLRRLLEPKELDRIKLPDIMRHPWM ||||| . .|| ||.||.|| .|||..|.||| |. | | .|. .||.| . |. . |||||.|..|... .|... .||.|||| APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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| Kinase | HUNKb.AA | CAMK | 94-343 | 25 | 7.29999999999e-118 | 381.54 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 94-343
Range on HMM: 1-425/425
Sequence Identity: 25% (107 aa)
VIGEGSFAKVRLGTHILTQ------------EQVAVKVIDKKLIAN------------------------RDYVRKNLRREATVLQK-------MRHTNI
..|.|||.||.|..|..|. ..||.|.|||| . . |.. |||.||| ...| ..| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI
ARLYEVLE------------TASN--------YYLVM---ELAEGG----TFMSFLCKR---------------RKLSERETRRYIRQLVTAVDHMHHLD
.|||| | | |. .|.|| |...|| ...... ....|||.|||.||.. ||...| ..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN
VIHRDIKIENFLLDNDQ-----------------NLKVIDFGLSNILGY------------------------DGFLRTQCGSPAYAA-PEIFCNSS---
..|||.| || |||.. |.|.||||..|.. . ..|.||.|.|.| ||.. ..
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN
-----------YGPSVDVWSIGVNMYAMLTGELPFVVDPPN----------NMSKLHARIMQGA-T-IPDTLTK-----------------------DCR
|||..|.||.|| .|.||.|..|| | | |...|. .||.| . .|. ... .|.
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK
DLLRRLLEPKELDRIKLPDIMRHPWM
||.|..|.. .|... ....||||
DLIRKMLQVDPEKRMTIEQCLNHPWM
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| Kinase | HUNKb.AA | HUNK | 89-236 | 60 | 9.80000000001e-116 | 376.92 | In-house | 1-163 (433) | Show / Hide |
Range on Protein: 89-236 Range on HMM: 1-163/433 Sequence Identity: 60% (99 aa) YILGDVIGEGSFAKVRLGTHILTQEQVAVKVIDKKLIANRDYVRKNLRREATVLQKMRHTNIARLYEVLETASNYYLVMELAEGGTFMSFLCKRR--KLS |.|||.||||||||||.|.|.||.|.||.||||||.|...|||.|||||||...|.|||.||.|||||.||..|||||||...||..|...|... .|. YLLGDKIGEGSFAKVREGMHVLTGEKVAIKVIDKKKIKKDDYVHKNLRREAQIMQMMRHPNIVRLYEVMETDNNYYLVMEYCPGGDLMHKVCEKKGGRLE ERETRRYIRQLVTAVDHMHHLDVIHRDIKIEN--------FLLDNDQNLK-----VIDFGLSN |...||||||||.||.||||..|.|||.|||| .|||.|.|.| .||||||| EGVARRYIRQLVSAVHHMHHHGVVHRDLKIENLETYLSLSLLLDDDHNIKNYVAFIIDFGLSN |
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| Kinase | HUNKb.AA | AMPK | 89-343 | 43 | 7.4e-115 | 342.41 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 89-343 Range on HMM: 1-254/254 Sequence Identity: 43% (112 aa) YILGDVIGEGSFAKVRLGTHILTQEQVAVKVIDKKLIANRDYVRKNLRREATVLQKMRHTNIARLYEVL-ETASNYYLVMELAEGGTFMSFLCKRRKLSE ||.|. ||||.| || .||||||.|.||.|...|. |.. | | . ..|| |...|| .| .||||. || . ..||| . || .. .|...|.| YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVER-IQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE RETRRYIRQLVTAVDHMHHLDVIHRDIKIENFLLDNDQNLKVIDFGLSNILGYDGFLRTQCGSPAYAAPEIFCNSSY-GPSVDVWSIGVNMYAMLTGELP ||..|.. | . .|. .|.. . ||| | || ||| ..|.|. ||||||. ||.| |||| |||||. . | || ||.|| || .|||| | || REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP FVVDPPNNMSKLHARIM-QGATIPDTLTKDCRDLLRRLLEPKELDRIKLPDIMRHPWM | . | ..| ..|. . .||. |.....||....|.. . ||. ||. ||| FDDE---NTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF |
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| Kinase | HUNKb.AA | AGC | 89-343 | 23 | 1.9e-100 | 259.82 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 89-343 Range on HMM: 1-395/395 Sequence Identity: 23% (93 aa) YILGDVIGEGSFAKVRLGTHI------LTQEQVAVKVIDKKL---IANRDYVRKN-----------LRREATVLQKMR----------HTNIAR-LYEVL . . |||.||| ||.| . |... |.||..|| | ... |... ...| .|.|.. | .| . |. FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF ETASN--YYLVMELAE---------GG-TFMSFLC---KRRKLSERETRRYIRQ-------LVTAVDHMHH-LDVIHRD-IKIENFLLDNDQNLKVIDFG .. .. |.|||... || ... |. |.....| ..| |. . .| |....| ...|||| .| || |||.| ..| ||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LSNILGYDG---------------------------------------------------FLRTQCG--SPAYAAPEIFCNSSYGPSVDVWS--IGVNMY |. .. || | || .| | ||||. ||...| || |. || LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY AMLTGELPFVVDPPN-------NMSKLHARIM-------QGATIP----------DTLTKDCRDLLRRLLEPKELDRIK----------LPDIMRHPWM |||| || |.|. | ... .|| .. ..| . ......||...||.. .|. .|..||| EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | HUNKb.AA | S_TKc | 89-343 | 30 | 6.8e-97 | 329.12 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 89-343
Range on HMM: 1-231/231
Sequence Identity: 30% (83 aa)
YILGDVIGEGSFAKVRLGTHILTQEQVAVKVIDKKLIANRDYVRKNLRREATVLQKMRHTNIARLYEVLETASNYYLVMELAEG--GTFMSFLCKRRK--
| ....||.|.|.||....|. |...||.|.|. ...||| .|.| .| || .||.| .. ...|.|||...| |. .....||..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG
----LSERETRRYIRQLVTAVDHMHHLDVIHRDIKIENFLLDNDQNLKVIDFGLSNILGYDGFLRTQCGSPAYAAPEIFCNSSYGP-SVDVWSIGVNMYA
..| ..|.|..|.. |....| . .||||.| || |||. ..|..||||. .| .|.||.| | |||.. .||. ..|.||.|. .|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE
MLTGELPFVVDPPNNMSKLHARIMQGATIPDTLTKDCRDLLRRLLEPKELDRIKLPDIMR-------HPWM
||.|. || .| .. .|. .....|..|..|. .|. .... |||.
MLCGYPPFP-----QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
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| Kinase | HUNKb.AA | MARK | 89-343 | 39 | 3.3e-96 | 314.96 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 89-343 Range on HMM: 1-262/262 Sequence Identity: 39% (105 aa) YILGDVIGEGSFAKVRLGTHILTQEQVAVKVIDKKLIANRD-YVRKNLRREATVLQKMRHTNIARLYEVLE--TASN-YYLVMELAEGGTFMSFLCKR-- | .. .||.||.|||.|..|..|...||.|...|. | .||..||. ...|. | || .|..| | | .. ||.||.|.|| .... .. YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKF--KLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPN RKLSERETRRYIRQLVTAVDHMHHLDVIHRDIKIENFLLDNDQ--NLKVIDFGLSNILGYDGFLRTQCGSPAYAAPEIFCNSSYG-PSVDVWSIGVNMYA ..|.|.|.||. ||.| || .| ...||||| || |.| . | | ||||.|.. . | | ||.|.|.||||| | | ||.|| || .|. GRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF MLTGELPFVVDPPNN--MSKLHARIMQG-ATIPDTLTKDCRDLLRRLLEPKELDRIKLPDIMRHPWM |..| .|| . . .|. .| | .||. . |.||.|..||| . .|... .||.|||| MVCGYFPFD---GDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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| Kinase | HUNKb.AA | Pkinase | 89-343 | 29 | 5e-84 | 290.27 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 89-343 Range on HMM: 1-293/293 Sequence Identity: 29% (88 aa) YILGDVIGEGSFAKVRLGTHILTQEQVAVKVIDKKLIANRDYVRKNLRR--EATVLQKMRHTNIARLYEVLETASNYYLVMELAEGG----TFMSFLC-- | .| .||.|||..|....|. |...||||.|.|. ... .....|| |. ......| || |||.. |. ...|.|||..||| .... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW KRRKL--SERETRRYIRQLVTAVDHMHHLDVIHRDIKIENFLLDNDQNL----KVIDFGLSNI--LGYDGFLRTQCGSPAYAAPEIFC-NSSYGPSVDVW ..... ||.| ..|..|.. .....| .||||.| ||.|.||. .. |..||||. . .. . | ||.| |.|||. .. |||.||.| RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW SIGVNMYAMLTGELPFVVD----PPNNMSKLHARIMQGATIPDT----------------------LTKDCRDLLRRLLEPKELDRIKLPDIMRHPWM |.|. .| ||.|..|| . . ... ....|||.. . | ....|.|.....|... .|. ..|. |||. SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | HUNKb.AA | QIK | 89-343 | 35 | 3e-81 | 276.25 | In-house | 1-272 (272) | Show / Hide |
Range on Protein: 89-343
Range on HMM: 1-272/272
Sequence Identity: 35% (99 aa)
YILGDVIGEGSFAKVRLGTHILTQEQVAVKVIDKKLIANRDYVRKNLRREATVLQKMRHTNIARLYEVLETASNYYLVMELAEGGTFMSFLCKRRK----
| .. || | || |.|..|. | ..||.|.||| . .... | . || .. ..| .| .||.|.|| . |.|.| ...| ||| .
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQK-CYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVK
----------------LSERETRRYIRQLVTAVDHMHHLDVIHRDIKIENFLLDNDQNLKVIDFGLSNILGYDGFLRTQCGSPAYAAPEIFCNSSY-GPS
..|.|.|| |...||.. |.. ..|||.| || ||||. | |..|||.|| . | | ||||.|||||.| .| ||
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK
VDVWSIGVNMYAMLTGELPFVVDPPNNMSKLHARIMQGA-TIPDTLTKDCRDLLRRLLEPKELDRIKLPDIMRHPWM
||.||.|| .|.. .| ||| . .. .| .|.. | || . .|| .| |. | |. |..|.||
VDIWSMGVVLYVLVCGALPFDGK---TLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
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| Kinase | HUNKb.AA | TSSK | 89-343 | 35 | 7.4e-81 | 265.1 | In-house | 1-289 (289) | Show / Hide |
Range on Protein: 89-343 Range on HMM: 1-289/289 Sequence Identity: 35% (102 aa) YILGDVIGEGSFAKVRLGTHILTQEQ----------------VAVKVIDKKLIANRDYVRKNLRREATVLQK-MRHTNIARLYEVLETAS-NYYLVMELA |..| .||.||.|||..... .. ||.|.||.| | .||..| | || .. | ..| || ..|| .|| . |.|||.| YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRK-KAPTDYLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYA EGGTFMSFLCKR------RKLSERETRRYIRQLVTAVDHMHHLDVIHRDIKIENFLLDNDQNLKVIDFGLSNILGYDG------FLRTQCGSPAYAAPEI |.|. .. .| . |.| ..|. ||.| ||...| ..| |||.| || ||| . |.| .||| .... | . | ||| ||||||| EHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYWPRDDPGRCCHLSKTFCGSYAYAAPEI FCNSSYGPSV-DVWSIGVNMYAMLTGELPFVVDPPNNMSKLHARIM-QGATIPD----TLTKDCRDLLRRLLEPKELDRIKLPDIMRHPWM .. | | . |||| || |.|..| .|| | | |. ... .... | .....|.||.|..|.| |.....|..|.|| LRGIPYDPKWYDVWSMGVILYIMVCGCMPFDDDK-SNIHKMLWQQQEHKVCFPKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM |
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| Kinase | HUNKb.AA | HUNK | 237-343 | 57 | 8.4e-80 | 258.25 | In-house | 321-433 (433) | Show / Hide |
Range on Protein: 237-343 Range on HMM: 321-433/433 Sequence Identity: 57% (65 aa) ILGYDGFLRTQCGSPAYAAPEIFCN-SSYGPSVDVWSIGVNMYAMLTGELPFVVDPP-NNMSKLHARIMQGAT--IPDTLT--KDCRDLLRRLLEPKELD |.||..|..|.|||||||||||.|. ..|||.||||||||||||||||.|||.|.|| .||..||..||.|.. .|...| .||...|||.|||.... IFGYEDFFKTHCGSPAYAAPEIYCRGKDYGPKVDVWSIGVNMYAMLTGTLPFTVEPPEFNMRHLHQKIMKGEMNVHPKQMTHLTDCDMFLRRKLEPDKIQ RIKLPDIMRHPWM |..|...|.|.|| RVNLQNKMDHRWM |
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| Kinase | HUNKb.AA | ULK | 89-343 | 28 | 3.6e-77 | 262.69 | In-house | 1-324 (324) | Show / Hide |
Range on Protein: 89-343
Range on HMM: 1-324/324
Sequence Identity: 28% (93 aa)
YILGDVIGEGSFA-KVRLGTHILT---QEQVAVKVIDKKLIANR------DYVRKNLRREATVLQKMR---HTN--IARLYEVLETA--SNYYLVMELAE
|.| ...|.|||. || |... | ...||.|.|||| . . .| ..|..| ...|. | | | .||...||. |.|..||. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN
GGTFMSFLCKRRK---------LSERETRRYIRQLVTAVDHMHHLDVIHRDIKIENFLLDNDQN------------LKVIDFGLSNILGYDGFLRTQC--
||.. ... |..| ||| |.. ...|.. . ..| .|||||| .| |. |.| ||. |||.. .. .... ..|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT
--------GSPAYAAPEIFC----NSSYGPS-VDVWSIGVNMYAMLTGELPFVVDPPNNMS----KLHAR-------IMQGATIPD------TLTKDCRD
|.| | ||.|. . |. . .|.||.|. .| ||.|. ||. . .|. || | . .. . ..|.|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD
LLRRLLEPKELDRIKLPDIMRHPWM
|.||.|. .| ||| ..| |||.
LIRRMLQYDEKDRISWEEIFNHPWF
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| Kinase | HUNKb.AA | ULK | 89-343 | 28 | 3.5e-74 | 252.77 | In-house | 1-329 (329) | Show / Hide |
Range on Protein: 89-343 Range on HMM: 1-329/329 Sequence Identity: 28% (94 aa) YILGDVIGEGSFAKVRLGTHILT----QEQVAVKVIDKK-LIANR-----DYVRKNLRREATVLQKMR--------HTNIARLYEVLETA--SNYYLVME |.| ...|.|||.|| |... | .|.||.|.|||. .. . .| . |..| ...|. | || .||...||. |.|..|| YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME LAEGGTFMSFLCKRRK----------LSERETRRYIRQLVTAVDHMHHLDVIHRDIKIENFLLDNDQN------------LKVIDFGLSNILGYD----G . .||...... |..| ||| |.. ...|.. . ..| .|||||| .| |..|.| ||. |||.. . .| YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ FLRTQC------GSPAYAAPEIFC----NSSYGPS-VDVWSIGVNMYAMLTGELPFVVDPPNNMS-----KLHAR-------IMQGATI-P-----DTLT . |. |.| | ||.|. . |. . .|.||.|. .| ||.|. ||. .| || | . . | ... MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS KDCRDLLRRLLEPKELDRIKLPDIMRHPWM ..|.||.||.|. .| ||| ... |||. PECKDLIRRMLQYDEKDRISWEELFNHPWF |
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| Kinase | HUNKb.AA | Pkinase_Tyr | 89-214 | 28 | 1.8e-17 | 59.76 | Pfam | 1-137 (270) | Show / Hide |
Range on Protein: 89-214 Range on HMM: 1-137/270 Sequence Identity: 28% (39 aa) YILGDVIGEGSFAKVRLGTHI----LTQEQVAVKVIDKKLIANRDY-VRKNLRREATVLQKM-RHTNIARLYEVLE-TASN--YYLVMELAEGGTFMSFL ..| ..|||.| .|..|| |. .||||.. | | . |. . ||| .. .. .| || ||| | .|.|||....| ..| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL CK----RRKLSERETRRYIRQLVTAVDHMHHLDVIHRDI | ...|. . . .| . .. . ||||. RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL |
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| Kinase | HUNKb.AA | TyrKc | 89-343 | 24 | 2.2e-16 | 42.07 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 89-343 Range on HMM: 1-280/280 Sequence Identity: 24% (71 aa) YILGDVIGEGSFAKVRLGTHILTQEQVAVKVIDKKLIANRDYVRKNLRREATVLQKM--RHTNIARLYEVLETA-------SNYYLVMELAEGGTFMSFL ||...||| | .|..|| . .|||||.. . |. ..||| .. | .| || ||| | . ...|||....| ..| ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL CKRRK-LSERETRRYIRQLVTAVDHMHHLDVIHRDIKIENFLLDNDQNLKVIDFGLSNILGYD-------GFLRTQC--GSP-----AYAAPEIFCNSSY |.|. |. .. . | .. |. .||||. | |..... |. ||||| .. | |.. |. ||| . . . RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF GPSVDVWSIGVNMYAMLT-GELPFVV---DPPNNMSKLHARIMQG--ATIPDT--------LTKDCRDLLRRLLEPKELDRIKLPDIMRHPWM . |||| || |. ..| |. | . . . ......|| .|. ... .. .. . . || .| | . TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |
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| UBA_CAMKL | HUNKb.AA | UBA_CAMKL | 366-403 | 24 | 2e-06 | 21.83 | In-house | 1-41 (41) | Show / Hide |
Range on Protein: 366-403 Range on HMM: 1-41/41 Sequence Identity: 24% (10 aa) DQRIIKALVQC--GHQEDILTECVQENRP-TSENAAYCLLA |..||. ... | ... ..|....|.. . |.|.||. DEEIIQEMCKMWHGFDREEIIESLRNNKYHNHITATYYLLL |
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