Gene HUNKa (Sea Urchin)

HUNKa

Species: Sea Urchin
Alias: HUNKa, Spk101, SPU_019837
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: HUNK

Sequence

Name Sequence Type Origin Length Description Download
HUNKa.AA Protein None 457 None Fasta, JSON
HUNKa.kin_dom Protein Kinase Domain None 374 None Fasta, JSON

Protein domain

Protein domains of HUNKa.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase HUNKa.AA HUNK 64-446 78 0.0 1039.45 In-house 1-401 (433) Show / Hide 
Range on Protein: 64-446
Range on HMM: 1-401/433
Sequence Identity: 78% (315 aa)

YLLGPTIGEGSFAKVKEAMHVLVGEKVAIKIIDKKAAREDAYLHKTLRREAGLLQLLGHAHIVRLLEVMETDNNLYLVLELCGGGPLLDKVCEKG--GLE
||||..|||||||||.|.||||.|||||||.||||....|.|.||.|||||...|...|..||||.||||||||.|||.|.|.||.|..|||||.  .||
YLLGDKIGEGSFAKVREGMHVLTGEKVAIKVIDKKKIKKDDYVHKNLRREAQIMQMMRHPNIVRLYEVMETDNNYYLVMEYCPGGDLMHKVCEKKGGRLE

EGVARRYIKQVASAVYHMHQMGVVHRDLKVEN--------LLLDDNDKIR-----IIDFGLSNFIGNLERETDLRDAKKRERDFSSRKQADVRASRRVSR
||||||||.|..|||.|||..||||||||.||        |||||...|.     ||||||||..|||||||||||||||||||||||||||||||||||
EGVARRYIRQLVSAVHHMHHHGVVHRDLKIENLETYLSLSLLLDDDHNIKNYVAFIIDFGLSNCCGNLERETDLRDAKKRERDFSSRKQADVRASRRVSR

TVGGRNGATGDDGGGPGRPGEPKGVARARLPSDDGTKRRTRGSSLREDNGQETWRERAGLQRKSSKEHPSMTRSNPKQNGVRFNGGNVRFPGQDVHRRMG
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
TVGGRNGATGDDGGGPGRPGEPKGVARARLPSDDGTKRRTRGSSLREDNGQETWRERAGLQRKSSKEHPSMTRSNPKQNGVRFNGGNVRFPGQDVHRRMG

AEEQDSPEKRRNMLRNRTLDVFGTRDFAGTLCGSPAYAAPEIIAR-KRYGPKVDVWSIGVNAYAMLTGTLPFIVEP--FNLRQLLSKIQKGEAGPLPSGL
||||||||||||||||||||.||..||..|.|||||||||||..| |.|||||||||||||.||||||||||.|||  ||.|.|..||.||| ...|  .
AEEQDSPEKRRNMLRNRTLDIFGYEDFFKTHCGSPAYAAPEIYCRGKDYGPKVDVWSIGVNMYAMLTGTLPFTVEPPEFNMRHLHQKIMKGEMNVHPKQM

S
.
T
Kinase HUNKa.AA CAMKL 64-448 26 7e-121 387.54 In-house 1-269 (297) Show / Hide 
Range on Protein: 64-448
Range on HMM: 1-269/297
Sequence Identity: 26% (113 aa)

YLLGPTIGEGSFAKVKEAMHVLV-GEKVAIKIIDKKAAREDAYLHKT-----------LRREAGLLQLLG---HAHIVRLLEVMETDNN------LYLVL
| .|.|.|.|||.||| |.|..  |||||||||||| ...| . .|            .|||. ....|    | .|..|.||.||...      .|||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCGGGP--LLDKVCEKGG----LEEGVARRYIKQVASAVYHMHQMGVVHRDLKVENLLLDDND--KIRIIDFGLSNFIG-NLERETDLRDAKKRERDFS
|.|.||   |.|.....|.    ..|. |||| .|. |||...|..|.||||.| ||.|||.|.  .| |||||.||..  .                  
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC------------------

SRKQADVRASRRVSRTVGGRNGATGDDGGGPGRPGEPKGVARARLPSDDGTKRRTRGSSLREDNGQETWRERAGLQRKSSKEHPSMTRSNPKQNGVRFNG
                                                                                                    
----------------------------------------------------------------------------------------------------

GNVRFPGQDVHRRMGAEEQDSPEKRRNMLRNRTLDVFGTRDFAGTLCGSPAYAAPEIIAR--K-RYGPKVDVWSIGVNAYAMLTGTLPFIVEPF------
                                   .||. ..  | ||||.|.||||...  |  .|||||.||.||  |||..|.|||  ..       
-----------------------------------IFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKD

NLRQLLSKIQKGEAGP-LPSGLSSG
|   |. || .|   |  .. .|  
NI-YLYWKIMCG-YYPPIWYHVS-D
Kinase HUNKa.AA CAMK 69-437 21 7.4e-106 342.16 In-house 1-363 (425) Show / Hide 
Range on Protein: 69-437
Range on HMM: 1-363/425
Sequence Identity: 21% (106 aa)

TIGEGSFAKVKEAMHVLVG------------EKVAIKIIDKKAARED------------------------AYLHKTLRREAGLLQLLG-------HAHI
|.|.|||.|||...| . .            .|||||||||| ....                        ..  | .|||  ....|        | .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRLLEVME------------TDNN--------LYLVL---ELCGGG----PLLDKVCEKGG---------------LEEGVARRYIKQVASAVYHMHQMG
..|.||.|            | ..        .|.|.   |.| ||     |.|...|.|.               ..|  ||||..|..||| ..|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHRDLKVENLLLDDND-----------------KIRIIDFGLSNFIGNLERETDLRDAKKRERDFSSRKQADVRASRRVSRTVGGRNGATGDDGGGPGR
.|||||| ||.|||||.                 .| |||||..|..   | .....| | .|   ..  |  .                          
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN--Q--W--------------------------

PGEPKGVARARLPSDDGTKRRTRGSSLREDNGQETWRERAGLQRKSSKEHPSMTRSNPKQNGVRFNGGNVRFPGQDVHRRMGAEEQDSPEKRRNMLRNRT
                                                                                                    
----------------------------------------------------------------------------------------------------

LDVFGTRDFAGTLCGSPAYAA-PEIIARKR--------------YGPKVDVWSIGVNAYAMLTGTLPFIVEP-----------FNLRQLLSKIQKGE
 . ... .   | ||.|.|.| ||.. .|.              ||||.|.||.||  |.||.|..||  .            .|...|. ||.||.
-TTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGK
Kinase HUNKa.AA CAMK1 64-419 23 1.5e-87 254.58 In-house 1-216 (276) Show / Hide 
Range on Protein: 64-419
Range on HMM: 1-216/276
Sequence Identity: 23% (87 aa)

YLLGPTIGEGSFAKVKEAMHVLV---GEKVAIKIID-KKAAREDA--YLHKTLRREAGLLQL---LGHAHIVRLLEVMETDNNLYLVLELCGGGPLLDKV
| .| .||.|.|..|... |      |...|||.|| ||.  ..      . |..| . ..    . | .|. . |. |.|| .|||.||. || |.|..
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQK-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRI

CEKGGLEEGVARRYIKQVASAVYHMHQMGVVHRDLKVENLLLDDN---DKIR--IIDFGLSNFIG-NLERETDLRDAKKRERDFSSRKQADVRASRRVSR
 |||   |  ||. .||..|||..||..|.|||||| ||||. |.    ||.  |.||||| ... . .                               
VEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDEN-------------------------------

TVGGRNGATGDDGGGPGRPGEPKGVARARLPSDDGTKRRTRGSSLREDNGQETWRERAGLQRKSSKEHPSMTRSNPKQNGVRFNGGNVRFPGQDVHRRMG
                                                                                                    
----------------------------------------------------------------------------------------------------

AEEQDSPEKRRNMLRNRTLDVFGTRDFAGTLCGSPAYAAPEIIAR---KRYGPKVDVWSIGVNAYAMLTGTLPF
                          .  | ||.| | |||....   | |. ..|.|||||  | .|.|  ||
--------------------------LMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVITYILLCGYPPF
Kinase HUNKa.AA MARK 64-419 24 1.6e-79 259.62 In-house 1-206 (262) Show / Hide 
Range on Protein: 64-419
Range on HMM: 1-206/262
Sequence Identity: 24% (91 aa)

YLLGPTIGEGSFAKVKEAMHVLVGEKVAIKIIDKKAAREDAYLHKTLRREAGLLQLLGHAHIVRLLEVME--TDNN-LYLVLELCGGGPLLDKVCEK--G
| .. |||.||.|||| | |.. |.||||||..|.   .   . | ..||. ....| | .|..|..|.|  | .. .||..|...||.|.| . ..  |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWM-KNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

GLEEGVARRYIKQVASAVYHMHQMGVVHRDLKVENLLLDDND--KIRIIDFGLSNFI--GNLERETDLRDAKKRERDFSSRKQADVRASRRVSRTVGGRN
 |.|  |||. .|. |||. .|....||||.| ||.|.|.|   .| |||||.|. |  |..                                      
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK--------------------------------------

GATGDDGGGPGRPGEPKGVARARLPSDDGTKRRTRGSSLREDNGQETWRERAGLQRKSSKEHPSMTRSNPKQNGVRFNGGNVRFPGQDVHRRMGAEEQDS
                                                                                                    
----------------------------------------------------------------------------------------------------

PEKRRNMLRNRTLDVFGTRDFAGTLCGSPAYAAPEIIARKRYG-PKVDVWSIGVNAYAMLTGTLPF
                       | ||.|.|.||||. .|.|  ||||.|| ||  |.|..|..||
---------------------LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPF
Kinase HUNKa.AA S_TKc 64-457 19 5.6e-68 233.07 SMART 1-231 (231) Show / Hide 
Range on Protein: 64-457
Range on HMM: 1-231/231
Sequence Identity: 19% (84 aa)

YLLGPTIGEGSFAKVKEAMHVLVGEKVAIKIIDKKAAREDAYLHKTLRREAGLLQLLGHAHIVRLLEVMETDNNLYLVLELCGG--GPLLDKVCEKGG--
| .. .||.|.|.||. . |.  |..||||||.           ...|||  .|.  .| .||.|..|... ..||.|.|.|.|  | |.|  ...|.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LEEGVARRYIKQVASAVYHMHQMGVVHRDLKVENLLLDDNDKIRIIDFGLSNFIGNLERETDLRDAKKRERDFSSRKQADVRASRRVSRTVGGRNG
    . | .||.|..|...|. ..|..|..||||| ||.|||.   | |.||||. ..                                          
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------------------

ATGDDGGGPGRPGEPKGVARARLPSDDGTKRRTRGSSLREDNGQETWRERAGLQRKSSKEHPSMTRSNPKQNGVRFNGGNVRFPGQDVHRRMGAEEQDSP
                                                                                                    
----------------------------------------------------------------------------------------------------

EKRRNMLRNRTLDVFGTRDFAGTLCGSPAYAAPEIIARKRYGP-KVDVWSIGVNAYAMLTGTLPFIVEPFNLRQLLSKIQKGEAGPLPSGLS--------
                      |.||.| | |||..    ||. |.|.||.|.  | ||.|  ||     .. ... ||        .. .         
---------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-------SPEAKDFIRKCLQ

-------SGTEYQQ-------IKTF
       .  |  |          |
KDPEKRPTA-EALQDEWDIKCHPWF
Kinase HUNKa.AA AMPK 64-211 46 9.9e-64 188.1 In-house 1-148 (254) Show / Hide 
Range on Protein: 64-211
Range on HMM: 1-148/254
Sequence Identity: 46% (70 aa)

YLLGPTIGEGSFAKVKEAMHVLVGEKVAIKIIDKKAAREDAYLHKTLRREAGLLQLLGHAHIVRLLEVM-ETDNNLYLVLELCGGGPLLDKVCEKGGLEE
|..| |||||.| ||| . | | ||||||||..|.  ....   . ..||  .|.|. | ||..| ||  ||   ...|.|   || | | .. .| |.|
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVER-IQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE

GVARRYIKQVASAVYHMHQMGVVHRDLKVENLLLDDNDKIRIIDFGLSN
  |.|...|. |.|  .|. ..|||||| ||||||.| .| | ||||||
REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSN
Kinase HUNKa.AA Ciliate-E2 64-437 16 6.9e-56 190.32 In-house 1-304 (365) Show / Hide 
Range on Protein: 64-437
Range on HMM: 1-304/365
Sequence Identity: 16% (76 aa)

YLLGPTIGEGSFAKVKEAMHVLVGE------------------KVAIKIIDKKAA--REDAYLH--KTLRREAG----------LLQLLGHAHIVRLLEV
| .   ||.|.|..|... . .|..                  ||.|||. .|    ..  ..   . . ||            .|..| | .|... |.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

ME--TDNNLYLVLELCGGGPLLDKVCEK-----------GGLEEGVARRYIKQVAS---------------AVYHMHQMG-VVHRDLKVENLLLDDNDKI
 .  .|||.|||.|.| || |.|   ..           . . |  .....||...               |. ..|. . ..|||.| ||.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RIIDFGLSNFIGNLERE--------------------TDLRDAKKRERDFSSRKQADVRASRRVSRTVGGRNGATGDDGGGPGRPGEPKGVARARLPSDD
 ||||||| .. . . .                    ....        .                                                  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD--------Q--------------------------------------------------

GTKRRTRGSSLREDNGQETWRERAGLQRKSSKEHPSMTRSNPKQNGVRFNGGNVRFPGQDVHRRMGAEEQDSPEKRRNMLRNRTLDVFGTRDFAGTLCGS
                                                                                           . . |.||.
---------------------------------------------------------------------------------------IIQQNMFNTICGT

PAYAAPEIIA---------RKRYGPKVDVWSIGVNAYAMLTGTLPFIVEPFNLRQLLSKIQKGE
| | ||||.          .|.|. |.|.||.||  | ||.| .||          . .|....
PGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----------QQQIKQCK
Kinase HUNKa.AA Pkinase 64-215 35 2.1e-54 191.84 Pfam 1-165 (293) Show / Hide 
Range on Protein: 64-215
Range on HMM: 1-165/293
Sequence Identity: 35% (60 aa)

YLLGPTIGEGSFAKVKEAMHVLVGEKVAIKIIDKKAAREDAYLHKTLRR--EAGLLQLLGHAHIVRLLEVMETDNNLYLVLELCGGG----PLLDKVC--
| .| .||.|||..|....|.  |..||.|||.|.  .|.   ..|.||  |. ... |.| .||||....|.....|.|.|.|.||     | | .   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

EKGGL--EEGVARRYIKQVASAVYHMHQMGVVHRDLKVENLLLDDNDKI----RIIDFGLSNF--IGN
..|..  .| ....|..|........|.||..||||| ||.|.|.|. |    .|.||||. .  . |
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-N
Kinase HUNKa.AA QIK 64-212 42 1.4e-53 184.31 In-house 1-167 (272) Show / Hide 
Range on Protein: 64-212
Range on HMM: 1-167/272
Sequence Identity: 42% (71 aa)

YLLGPTIGEGSFAKVKEAMHVLVGEKVAIKIIDKKAAREDAYLHKTLRREAGLLQLLGHAHIVRLLEVMETDNNLYLVLELCGGGPLLDKVCEKGG----
| .. ||| | || || | |    .||||||||| .  |. .| | . ||  .. .| | ||..|..|||||. .|.| | | .| . | .|..|     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEE-NLQK-CYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVK

----------------LEEGVARRYIKQVASAVYHMHQMGVVHRDLKVENLLLDDNDKIRIIDFGLSNF
                ..| .|||  .|..|||.. |. ..|||||| ||.||| |  | |.|||.||.
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNW
Kinase HUNKa.AA TSSK 64-208 38 6.6e-48 155.31 In-house 1-168 (289) Show / Hide 
Range on Protein: 64-208
Range on HMM: 1-168/289
Sequence Identity: 38% (65 aa)

YLLGPTIGEGSFAKVKEAMHVLVGEK----------------VAIKIIDKKAAREDAYLHKTLRREAGLLQL-LGHAHIVRLLEVMETDN-NLYLVLELC
| .| .||.||.|||..| .     |                |||||||.| | .| || | | ||   .   | | .|....|  || .   |.|.|..
YNVGKKIGHGSYAKVYCAYSKKHKCKHNPRLRDDLRIKRHTHVAIKIIDRKKAPTD-YLNKFLPREIQIMRKTLKHPNIIQFYEMFETCQGKIYMVMEYA

GGGPLLDKVCEK------GGLEEGVARRYIKQVASAVYHMHQMGVVHRDLKVENLLLDDNDKIRIIDFG
 .| ||... ..      |.|.|  ||.  .| .||| ..| ..||||||| ||.|||..  | ..|||
EHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFG
Kinase HUNKa.AA CAMK-Unique 64-210 21 1.4e-42 138.3 In-house 1-220 (363) Show / Hide 
Range on Protein: 64-210
Range on HMM: 1-220/363
Sequence Identity: 21% (48 aa)

YLLGPTIGEGSFAKVKEAMHVLVGEKVAIKIIDKKAAREDAYLH----------------KTLRREAGLLQLLGHAHIVRLLEV----METDN-------
| ..  ||.|.| .|.|.|    | | |.|.. |... .....                   |.||........| .|..|...     ....       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------NLYLVLELCGGGPLLDKVCE--------------------KGGLEE--GVARRYIKQVASAVYHMHQMGVVHRDLKVENLLLDDN--D----
        ..|.|.|.| || |.|.. .                    .| ..|    ..... ...||| .||. ..|||||| ||...  .  |    
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

----------KIRIIDFGLS
          .| ..||||.
RDFPYDWSNWHIKLCDFGLC
Kinase HUNKa.AA AMPK 378-419 67 4.3e-22 62.45 In-house 158-200 (254) Show / Hide 
Range on Protein: 378-419
Range on HMM: 158-200/254
Sequence Identity: 67% (29 aa)

TLCGSPAYAAPEIIARKRY-GPKVDVWSIGVNAYAMLTGTLPF
| |||| |||||.|. |.| ||.||.|| ||  |||| |.|||
TACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF
Kinase HUNKa.AA Pkinase_Tyr 64-210 27 3.3e-20 69.06 Pfam 1-158 (270) Show / Hide 
Range on Protein: 64-210
Range on HMM: 1-158/270
Sequence Identity: 27% (44 aa)

YLLGPTIGEGSFAKVKEAMHV----LVGEKVAIKIIDKKAAREDAYLHKTLRREAGLLQLL-GHAHIVRLLEVME-TDNN--LYLVLELCGGGPLLDKVC
  .| ..|||.| .|...         . .||.|.. |  | ... ... . ||| ..  |  | .||||. |    .    .|.|.|.. .| |||   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----KGGLEEGVARRYIKQVASAVYHMHQMGVVHRDLKVENLLLDDNDKIRIIDFGLS
.    |. |       .  |.|..  . .... .||||   | |...| ...| ||||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase HUNKa.AA CAMK-Unique 378-419 35 1.7e-16 50.82 In-house 234-293 (363) Show / Hide 
Range on Protein: 378-419
Range on HMM: 234-293/363
Sequence Identity: 35% (21 aa)

TLCGSPAYAAP--------------EIIARKRYGPKV----DVWSIGVNAYAMLTGTLPF
| ||.| |.||              |.|.. .|. ..    | ||.|| .| ||.| .||
TMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPF
Kinase HUNKa.AA TSSK 377-419 56 3.4e-15 46.32 In-house 186-229 (289) Show / Hide 
Range on Protein: 377-419
Range on HMM: 186-229/289
Sequence Identity: 56% (25 aa)

GTLCGSPAYAAPEIIARKRYGPKV-DVWSIGVNAYAMLTGTLPF
.| ||| |||||||.  . | ||. |||| ||  |.|..|..||
KTFCGSYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVCGCMPF
Kinase HUNKa.AA QIK 378-428 56 5.4e-15 54.64 In-house 176-228 (272) Show / Hide 
Range on Protein: 378-428
Range on HMM: 176-228/272
Sequence Identity: 56% (30 aa)

TLCGSPAYAAPEIIARKRY-GPKVDVWSIGVNAYAMLTGTLPFIVEPF-NLRQ
| ||||.|||||.   | | |||||.||.||  |.. .| |||. .   ||||
TWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQ
Kinase HUNKa.AA Pkinase 378-419 55 1.6e-14 52.46 Pfam 170-212 (293) Show / Hide 
Range on Protein: 378-419
Range on HMM: 170-212/293
Sequence Identity: 55% (24 aa)

TLCGSPAYAAPEIIA-RKRYGPKVDVWSIGVNAYAMLTGTLPF
|.||.| |.|||.|  .. ||||||.||.|.  | ||.| .||
TFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF
Kinase HUNKa.AA TyrKc 64-370 14 2.8e-12 -24.22 SMART 1-280 (280) Show / Hide 
Range on Protein: 64-370
Range on HMM: 1-280/280
Sequence Identity: 14% (55 aa)

YLLGPTIGEGSFAKVKEAMHVLVGEKVAIKIIDKKAAREDAYLHKTLRREAGLLQLL--GHAHIVRLLEVMETD-------NNLYLVLELCGGGPLLDKV
  || ..||| | .| ...     ..||.| . . |       .. ..||| ..  |   | .||||. |  ..         |..|.|.. .| |.|  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

CEKGG-LEEGVARRYIKQVASAVYHMHQMGVVHRDLKVENLLLDDNDKIRIIDFGLSNFIGNL------ERETDLR---DAK--------------KR--
 .... |       .  |.|.   . |.....||||   | |...|  ..| ||||| .|..       .   . .   ..|              ..  
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

--------------------ERDFSS-----RKQADVRASRRVSRTVGGRNG----ATGDDGGGPGRPGEPKGVARARLPSDDGTKRRTRGSSLREDNGQ
                    .   .       . ..|..  .  .           .                                           
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------------------------

ETWRERAGLQRKSSKEHPSMTRSNPKQNGVRFNGGNVRFPGQDVHRRMGAEEQDSPEKRRNMLRNRTLDVF
                               |    |. | ..... |    .  ||.| ..      . |
-------------------------------F----VCCP-DEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase HUNKa.AA Pkinase_Tyr 387-404 50 2.975122 1.48 Pfam 182-199 (270) Show / Hide 
Range on Protein: 387-404
Range on HMM: 182-199/270
Sequence Identity: 50% (9 aa)

APEIIARKRYGPKVDVWS
||| |. ...  | ||||
APECINYGKFTTKSDVWS