DAPK

Species: Sea Urchin
Alias: SPU_025882, DAPK, SPU_014404, Spk062
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CAMK
Family: DAPK
Subfamily: DAPK

Sequence

Name Sequence Type Origin Length Description Download
DAPK.AA Protein None 1540 None Fasta, JSON
DAPK.kin_dom Protein Kinase Domain None 187 None Fasta, JSON

Protein domain

Protein domains of DAPK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DAPK.AA DAPK 13-201 64 1.3e-177 516.92 In-house 1-192 (264) Show / Hide
Range on Protein: 13-201
Range on HMM: 1-192/264
Sequence Identity: 64% (124 aa)

YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELS-HDNIISLHDAFELQKEVVLILELVTGGELFHYLAEEDHV
|..||.||||||..|||..||||||.||.|||.|||.|||||||.||||.||||||.|.. |.|||.|||..|....||||||||.|||||..|.|....
YDMGEEIGSGQFAVVKKCREKSTGKEYAAKFIKKRRYTASRRGVSREDIEREVSILREIRGHPNIITLHDVYENKTDVVLILELVSGGELFDFLCEKECL

NEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQN--IMLIDFGLSRRIKPGEDIRDIMGTAEFVAPEIINFEPLSLNTDMWPV
|||.|.||.|.||....|||...|||.||||||||||.||..|  |..|||||..||.||.....|.||.|||||||.|.|||.|.|||| .
NEEEATQFIKQILDGVHHMHSKHICHFDLKPENIMLLDRNVPNPRIKIIDFGLAHRIEPGNEFKNIFGTPEFVAPEIVNYEPLGLETDMWSI

Kinase DAPK.AA DAPK 15-201 58 2.5e-163 453.9 In-house 1-192 (264) Show / Hide
Range on Protein: 15-201
Range on HMM: 1-192/264
Sequence Identity: 58% (112 aa)

IGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELS-HDNIISLHDAFELQKEVVLILELVTGGELFHYLAE--EDHV
.||..|.|||..|.|...|||||.||.|||.|||...|||||.||.|..|..||||.. |.|.|.||...|....|.||||.|.|||||.|..|  |...
MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDREECL

NEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQN--IMLIDFGLSRRIKPGEDIRDIMGTAEFVAPEIINFEPLSLNTDMWPV
.||.|..|.|.|||.....|.||||||||||.||||..||...  |..|||||||.|..||..||||||.|.|||||.|.|||||.|||| .
CEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKICNGEEFRDIMGTPEYVAPEIVNYEPLSLATDMWSI

Kinase DAPK.AA MLCK 13-199 44 5.5e-107 282.87 In-house 1-183 (257) Show / Hide
Range on Protein: 13-199
Range on HMM: 1-183/257
Sequence Identity: 44% (84 aa)

YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELSHDNIISLHDAFELQKEVVLILELVTGGELFHYLA-EEDHV
|||.|..| | |. | ...|||||| .| |||.       |.....|....|..|. .| | |.| .||||| ..|.|.|.|...||||| .   |..| 
YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKC------RKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHL

NEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQNIMLIDFGLSRRIKPGED-IRDIMGTAEFVAPEIINFEPLSLNTDMW
.|.. . ... |.|...|||..||.||||||||||. .|.  .| .||||| |...|.|. ..   || ||||||..|..|... ||||
TEREVIHYMRQICEGVHHMHWQNIVHLDLKPENIMCQTRTSHQIKIIDFGLARKYDPDEKKVKVMFGTPEFVAPEVVNYDPVGFQTDMW

Kinase DAPK.AA CAMK 18-199 21 6.3e-74 237.41 In-house 1-318 (425) Show / Hide
Range on Protein: 18-199
Range on HMM: 1-318/425
Sequence Identity: 21% (68 aa)

DIGSGQFSEVKKVTEKSTG------------KDYAGKFIRKRRSTAS----------------------RRGVKREDIVREVSILEELS-------HDNI
 .|.|.|..||....|.|.            . .| |.| |.. . .                      ||...|. . ||..|.  |.       | ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISLHDAFEL-------------------QKEVVLIL---ELVTGGEL----FHYLAEE---------------DHVNEEVAAQFVKKILEALKHMHDRNI
|.|....|                    .|......   |...||||    | |. |                 ...|. |..... |..|....|..||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

CHLDLKPENIMLLNRNT---------------QNIMLIDFGLSRRIKP------------------------GEDIRDIMGTAEFVA-PEIINF------
.|.|||||||.| ..|.                || .||||......|                        |.  ..  || |..| ||..|       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------EPLSLNTDMW
        .. .  .|||
QNATDEEKPYYGPKCDMW

Kinase DAPK.AA DRAK 16-201 38 9.6e-71 218.91 In-house 2-187 (259) Show / Hide
Range on Protein: 16-201
Range on HMM: 2-187/259
Sequence Identity: 38% (73 aa)

GEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEE-LSHDNIISLHDAFELQKEVVLILELVTGGELFH--YLAEEDHVN
. . | |.|  | |  .|.||...| ||..|||   .     |..|..|. .|.   . ...| ||. .| . |..|.||. .|||.|.   . .|. . 
AKERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDC----RMEILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFC

EEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLL-NRNTQNIMLIDFGLSRRIKPGEDIRDIMGTAEFVAPEIINFEPLSLNTDMWPV
|. . . ...|||... .|.||| |||||| ||.|   .    | ..|||.|| |. ||..|.|||| ..||||| |..|... |||| .
EKDVQRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEEVREIMGTPDYVAPEILNYDPITMATDMWSI

Kinase DAPK.AA Trio 13-201 35 6.2e-68 172.92 In-house 1-186 (258) Show / Hide
Range on Protein: 13-201
Range on HMM: 1-186/258
Sequence Identity: 35% (69 aa)

YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELSHDNIISLHDAFELQKEVVLILELVTGGELFHYLAEEDHVN
| . | || | || |.....|.||.. | |||       . |  ..|   .| ..|  |.|. ..||||..|  .  .||||| ..|||  .|.. . . 
YTFQEEIGRGRFSVVRRCWHKATGRTCAAKFI-------PYRMMDKEQVYHEYEMLQHLQHPCVCSLHDTYETPRHYILILELCDDGELLCCLMRWGSYC

EEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNT--QNIMLIDFGLSRRIKPG--EDIRDIMGTAEFVAPEIINFEPLSLNTDMWPV
|.  . ..  .|||.   |   | |||.||||.|.  .|   . | ..|||    . |.  | .    |. ||.|||||. .| |. || |..
ESEVKTYMWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSI

Kinase DAPK.AA CAMK1 13-199 35 8.5e-66 190.23 In-house 1-200 (276) Show / Hide
Range on Protein: 13-199
Range on HMM: 1-200/276
Sequence Identity: 35% (72 aa)

YQIGEDIGSGQFSEVKKVTEKST---GKDYAGKFIR-KRRSTASRRGVKREDIVREVSILE---ELSHDNIISLHDAFELQKEVVLILELVTGGELFHYL
|..|. ||.| ||||...|.|.|   ||.|| | |  |.    ...  |.| . .|..|.    ...| |||.... .|  ... |..|||||||||.  
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQ-KQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRI

AEEDHVNEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNR-NTQNIM--LIDFGLSRRIKPGED-IRDIMGTAEFVAPEIINF---EPLSLNTDM
 | .. .|. |.  .|.||.|...||...|.| ||||||. . .  .   |.  ..|||||......|.   .  || ..||||...    .| .   ||
VEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDM

W
|
W

Kinase DAPK.AA Ciliate-E2a 13-188 33 1.8e-57 167.74 In-house 1-183 (275) Show / Hide
Range on Protein: 13-188
Range on HMM: 1-183/275
Sequence Identity: 33% (62 aa)

YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELSHDNIISLHDAFELQKEVVLILELVTGGELFHYLAEEDHVN
| .   ||.|.|  |.... | |||..| | . | .   .  . ..| . .|..|. .|.|.||| |.. .|  .   |..|.. ||||.... . .  .
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQ--KKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFF

EE--VAAQFVKKIL-EALKHMHDRNICHLDLKPENIMLL--NRNT---QNIMLIDFGLSRRIKPGED--IRDIMGTAEFVAPEIIN
||  ..... ...| ..| .|| ||| | |||||||..   . |    ..|..|||||...|.. |   .  . ||. .||||..|
EEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLN

Kinase DAPK.AA Pkinase 13-199 30 9.2e-56 196.36 Pfam 1-196 (293) Show / Hide
Range on Protein: 13-199
Range on HMM: 1-196/293
Sequence Identity: 30% (63 aa)

YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASR------RGVKREDIVREVSILEELSHDNIISLHDAFELQKEVVLILELVTGG----ELF
|.||. |||| |..|.| ..|.||| .| | |.||.   .       .        .|..|. .|.|.||. |.|.||  ... ...|.. ||    .||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF

HYLA--EEDHV--NEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQN---IMLIDFGLSRR--IKPGEDIRDIMGTAEFVAPEIIN-FEPL
.|.   ..  .   |...  ... ||..|...|...|.| |||||||..  .| ..   . ..||||..   . ...   .. || ...|||.|.  .. 
DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYY

SLNTDMW
.   |||
GPKVDMW

Kinase DAPK.AA CAMKL 13-191 30 2e-51 162.27 In-house 1-211 (297) Show / Hide
Range on Protein: 13-191
Range on HMM: 1-211/297
Sequence Identity: 30% (65 aa)

YQIGEDIGSGQFSEVKKVTE-KSTGKDYAGKFIRKRRST--ASRRGV------KRED-IVREVSILEELS---HDNIISLHDAF-------ELQKEVVLI
|.||. .| | |..||  |  . ||. .| |.| |.. .     .        .. . | ||..|.. |.   | |||.|.. .       |  |...|.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-KKIYLV

LELVTGGE--LFHYLAEEDH----VNEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQNIMLIDFGLSRRIKP-----GEDIRDIMGTAEF
.|.. |||  ||.|. .. |      |. | .. . |..|....|...|.| |.|||||.| ... .|| .||||.|  ..|     |.  .   |. ..
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

VAPEIINF--EP
 ||||..   .|
MAPEIFQGNNKP

Kinase DAPK.AA S_TKc 13-274 24 1.1e-50 175.66 SMART 1-231 (231) Show / Hide
Range on Protein: 13-274
Range on HMM: 1-231/231
Sequence Identity: 24% (69 aa)

YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELSHDNIISLHDAFELQKEVVLILELVTG--GELFHYLAEEDH
|.|.. ||.| |..|.|...|.||. .| | |.             |.| ||..||..  |.||. |.|.|.  ... ...|.. |  |.||.|. .  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------VNEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQNIMLIDFGLSRRIKPGEDIRDIMGTAEFVAPEIINFEPLSL-NTDMWPV--
       .| .|. ... |..||...|...|.| |||||||.| .    .|...||||.|..      . . || ...|||..   . .    |.| .  
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

----FISSRLPNIQLIQLSRSQVIQLVCVFISPKMGHRREQLALRKMSKALRSDWEHGETALHLAAGYGHVDILEYL
    ... . |          .......            . |.  ..| |. | |.  ||  . ..  .. . ...
ILYEMLCGYPPFP-----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase DAPK.AA RSK 15-188 30 3.8e-45 156.29 In-house 1-181 (278) Show / Hide
Range on Protein: 15-188
Range on HMM: 1-181/278
Sequence Identity: 30% (56 aa)

IGED--IGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEELS-HDNIISLHDAFELQKEVVLILELVTGGELFHYLAEEDH-
. ..  .| | .. ..|.| . ||. || | ..|.   .. .    ..  .|..|||.   | .|..||.||. .... ||.|.. |||||  | .| | 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKD--TRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHF

--VNEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNT-QNIMLIDFGLSRR--IKPGEDIRDIMGTAEFVAPEIIN
    |. |..   .|  |..|.|.. | | |||||||.. ....   |.|.|||...   .. ..      .|.|..|||...
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLK

Kinase DAPK.AA TyrKc 13-271 22 3.9e-11 -42.69 SMART 1-280 (280) Show / Hide
Range on Protein: 13-271
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

YQIGEDIGSGQFSEVKKVTEKSTGKDYAGKFIRKRRSTASRRGVKREDIVREVSILEEL--SHDNIISLHDAFELQ-------KEVVLILELVTGGELFH
 . |. .|.|.| || | | |    . | | ...           |||. || .|. .|  .|.||. |. .   |       . . ...|.. .| | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

YLAEEDH-VNEEVAAQFVKKILEALKHMHDRNICHLDLKPENIMLLNRNTQNIMLIDFGLSRRIKPG------EDIRDIMG--TAEFV------APEIIN
|| .  . .. .   .|   | .   . |..|. | ||   |... ...   .   |||||| |. .      .|  . ..   . ..      ||| ||
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

FEPLSLNTD-------MWPVFISSRLPNIQLIQ--LSRSQVIQLVCVFISPKMGHRREQLAL--------------RKMSKALRSDWEHGETALHLAAGY
.   .  .|       || .|     |    ||  .| ..||..|      | |.|..| .               . |..  . | |   |   .    
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV------KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI----

GHVDIL
  ....
--HECF

Kinase DAPK.AA Ank 386-418 48 7.9e-11 43.32 Pfam 1-33 (33) Show / Hide
Range on Protein: 386-418
Range on HMM: 1-33/33
Sequence Identity: 48% (16 aa)

HGITPLHHAVRRQHYDIVKYLVDSNCDVNLQDK
.| |||| |.|. |...||.|.. ..|||.||.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Kinase DAPK.AA Ank 320-352 39 3.6e-10 40.95 Pfam 1-33 (33) Show / Hide
Range on Protein: 320-352
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

DGETPLHIAAWHGYTSIVQTLCKAGATLDLKNK
||.||||.|. .|.|..|. | ..|| ......
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Kinase DAPK.AA Ank 254-286 36 1.3e-09 38.88 Pfam 1-33 (33) Show / Hide
Range on Protein: 254-286
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

HGETALHLAAGYGHVDILEYLQAKGASIDVADK
.|.|.||||. .||......|  .||.... |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Kinase DAPK.AA Ank 353-385 42 4.8e-08 33.26 Pfam 1-33 (33) Show / Hide
Range on Protein: 353-385
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

DGETTLLCAAARGHLDIVKILVEAGALLNTIDK
||.| | .|. .||...|| |...|| .|  |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Kinase DAPK.AA Ank 452-484 36 5.9e-07 29.35 Pfam 1-33 (33) Show / Hide
Range on Protein: 452-484
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

HKNSALHMAARGGHIEVVRYLCLAGALIHQRNQ
. ...||.|.| ||.|||..|  .|| .. .. 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Kinase DAPK.AA Ank 287-319 39 1.6e-05 24.15 Pfam 1-33 (33) Show / Hide
Range on Protein: 287-319
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

TGETPLHVAGRYGQVEAVQYLCDQAVNSNLADE
 |.||||.| |.|..| |..| ..  . |. | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Kinase DAPK.AA Ank 419-451 36 0.000348 19.35 Pfam 1-33 (33) Show / Hide
Range on Protein: 419-451
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

LGDTPLNVACKEGALDLVEMLHAVGAKRDILNR
 |.||| .||. | .. |.||   ||  .. ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Kinase DAPK.AA Pkinase_Tyr 57-105 30 0.002743 11.76 Pfam 46-98 (270) Show / Hide
Range on Protein: 57-105
Range on HMM: 46-98/270
Sequence Identity: 30% (16 aa)

KREDIVREVSILEEL-SHDNIISLHDAFE-LQKE--VVLILELVTGGELFHYL
.|||  ||..|. .| .|.||..|. .    ..   . ...|.. .| | .||
CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

Kinase DAPK.AA Pkinase_Tyr 13-29 41 0.17234 5.67 Pfam 1-17 (270) Show / Hide
Range on Protein: 13-29
Range on HMM: 1-17/270
Sequence Identity: 41% (7 aa)

YQIGEDIGSGQFSEVKK
 ..|. .|.|.| ||.|
ITFGKKLGEGAFGEVYK

Kinase DAPK.AA Ank 485-505 42 0.694139 7.45 Pfam 1-21 (33) Show / Hide
Range on Protein: 485-505
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

DGLTASQLASLEGHEDVADVL
|| |.  ||.. ||..|.  |
DGFTPLHLACRCGHTEVVKML

ROC DAPK.AA ROC 528-781 14 7.3e-18 56.85 In-house 1-215 (215) Show / Hide
Range on Protein: 528-781
Range on HMM: 1-215/215
Sequence Identity: 14% (41 aa)

LHRIRIKVLGQSGVGKTALIDSLKCGYFRGLFRRSRSNISLIGSSSNGRSSPRSPRSPRSPLTPMFGNGKKMDGGRFFMESLKRKQLSSTSSSFDVDSEV
......  .|| ||||| |. .|... |   .  |.                                                            . . 
CNEMKLMLCGQGGVGKTSLCKQLMHDKFSDCSCYSC---------------------------------------------------------DKGNHPT

TRGIE-FTHGTIPGA----------GDFTFLEFSGEDTYHTAYPHFLSDEGAIHLVVFSLDD---MFEEQ----LAQ--VTYWMNFLRSQLPATEPVGYC
| |||     ....           ..| . .| | . ||  . .||.   ...|.|... .    ....    . .  . ||..|..|  |  |.    
THGIEPIQQWVLDCKDMMFRKKEDEIKFNVWDFGGQEIYHATHQFFLTNHRSVYLLVWDCRTKCCDGQPEMIVRECNYELEYWLRFIKSRGPQSEH-HCM

GKYRQQPKIALVATHADHTQCPKQP----------TGELISGEGNIVLYQTKRLFGRLFD----ICDVLFVMDANSAQS-KDVKMLRTH
..    ... .|.||.|     . .          . .|            .  |.. .     |    .. ....... |....||.|
QP----SPVIIVGTHWDKVPRQDNKVYQHKQCCRMWQKL------------RNKFPNICHSWMQIEHYQGFFHVDCETGCKGIDKLRHH

Kinase DAPK.AA RSK 533-543 72 0.328679 0.63 In-house 1-11 (278) Show / Hide
Range on Protein: 533-543
Range on HMM: 1-11/278
Sequence Identity: 72% (8 aa)

IKVLGQSGVGK
.||||| |.||
LKVLGQGGYGK

ROC DAPK.AA ROC 809-1062 14 2.1e-17 55.34 In-house 1-215 (215) Show / Hide
Range on Protein: 809-1062
Range on HMM: 1-215/215
Sequence Identity: 14% (41 aa)

LHRIRIKVLGQSGVGKTALIDSLKCGYFRGLFRRSRSNISLIGSSSNGRSSPRSPRSPRSPLTPMFGNGKKMDGGRFFMESLKRKQLSSTSSSFDADSEV
......  .|| ||||| |. .|... |   .  |.                                                            . . 
CNEMKLMLCGQGGVGKTSLCKQLMHDKFSDCSCYSC---------------------------------------------------------DKGNHPT

TRGIE-FTHGTIPGA----------GDFTFLEFSGEDTYHTAYPHFLSDEGAIHLVVFSLDD---MFEEQ----LAQ--VTYWMNFLRSQLPATEPVGYC
| |||     ....           ..| . .| | . ||  . .||.   ...|.|... .    ....    . .  . ||..|..|  |  |.    
THGIEPIQQWVLDCKDMMFRKKEDEIKFNVWDFGGQEIYHATHQFFLTNHRSVYLLVWDCRTKCCDGQPEMIVRECNYELEYWLRFIKSRGPQSEH-HCM

GKYRQQPKIALVATHADHTQCPK-------QPT--GEMISGEGNIVLYQTKRLFGRLFD----ICDVLFVMDANSAQS-KDVKMLRTH
..    ... .|.||.|     .       |.    ...           .  |.. .     |    .. ....... |....||.|
QP----SPVIIVGTHWDKVPRQDNKVYQHKQCCRMWQKL-----------RNKFPNICHSWMQIEHYQGFFHVDCETGCKGIDKLRHH

Kinase DAPK.AA COR 1063-1204 15 3.5e-15 45.36 In-house 1-184 (434) Show / Hide
Range on Protein: 1063-1204
Range on HMM: 1-184/434
Sequence Identity: 15% (29 aa)

ISSLRNSILK-------VEAPVSVLCEAVASALPAWR---RTFVNFPVLTWQQFSEGIHASINP--------LAGQAHLREVGRQLHLMGEVQCFG----
|   . .|..       .. ||   .... ..| ..|   .   ..|...|..|..    . .|        .   . |. | ..|| .|..  |.    
IRKTAKKIKHKQMFEDYMCQPVPQSWWKCKQKLEEMRKWMNRHNEKPWMSWKEFCQICQEHGPPKRLRHQNIIIDEDELHTVAMYLHDLGHIIHFKIWDH

SELLQEVIVIEPTWLCSGIIGRLLSHDATE-----QPEGQ-YSIHYIQSLFP---------------DTDAMDISQLMEAMDICV
 . |....|..| |.|  .......|  .       . |  .. . .. ...               |.|. .. .|||....|.
DPMLKDFVVLDPQWFCQ-MMYHIFNHKESRCFHKLHNKGIFFTHQDLEKIWNPPCRHNPHMNWRRYPDHDHEYLVELMEKFELCY

Kinase DAPK.AA RSK 814-824 72 0.328679 0.63 In-house 1-11 (278) Show / Hide
Range on Protein: 814-824
Range on HMM: 1-11/278
Sequence Identity: 72% (8 aa)

IKVLGQSGVGK
.||||| |.||
LKVLGQGGYGK

COR DAPK.AA COR 1250-1415 18 2.4e-15 45.89 In-house 248-434 (434) Show / Hide
Range on Protein: 1250-1415
Range on HMM: 248-434/434
Sequence Identity: 18% (36 aa)

LPSGLFSRIQMSLRRNFQQDM----EDTTDNELVMWRNGAKCSSGSI---EGLISMTNDECAIEIKVRGYNDTRQG-CFIFLEDLVHLVKHVLVDSY--P
||.|...| |  | . . ...    | .   | . ||||.. . .     |.|... |....| | |||  |.  . |  ..  .  ...|.. ...  |
LPAGFWPRFQVRLHHFIHDMFKCFYERSC-CEWMYWRNGMVLKWEGHNKNEALVKCDNHDNKIYITVRGCQDCWIDMCCQLWQIIRQHIQHIHNSWWPWP

GLP-------LNMEVLSPIQLSSHEK-TIM--VYNACSLLRLQLRTERTVENPISN-QEEDFVDIFCFGSE---SVESNLIAGVDL-HLSE
||.       .. ....| ..  |.    .   |.  ...|.. . .... .| ..  .. | .. |.. .   | ..   .| .  ..|.
GLQYQCQHWVCREWIPCPHCIQDHWDTCCDICYYQYDWCIRAEEMGMDSYPCPKCDQYCDAFEMMCCYQHHWHYSHDQ---NGQWIQRISD

Death DAPK.AA Death 1422-1508 25 8.1e-11 38.57 Pfam 1-87 (87) Show / Hide
Range on Protein: 1422-1508
Range on HMM: 1-87/87
Sequence Identity: 25% (23 aa)

RQISMLLDPPDPMGKDWCLLAVGLGL-TEKIPMLDTLNRRCGPDESDSPTERLLQEWGKE--ETNSVGVLLNKVKDLGREDVLRVLMQGS
.... ||||....||||. ||  ||.  ..|  . .    . |. . |.|...|. |     .  .|. |.   ...|| |..... . .
QKLCRLLDPDHHPGKDWRRLARKLGMSDNEIDQIEHD---QNPHDLRSQTYQMLWKWEQRHGKNATVDHLIEALRKMGRRDCAEKIQSWL