TTN

Species: Sea Urchin
Alias: SPU_005613, Spk071, TTN
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CAMK
Family: MLCK

Sequence

Name Sequence Type Origin Length Description Download
TTN.AA Protein None 7569 None Fasta, JSON
TTN.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of TTN.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FN3 TTN.AA FN3 1-83 26 2.7e-14 54.73 SMART 2-69 (69) Show / Hide
Range on Protein: 1-83
Range on HMM: 2-69/69
Sequence Identity: 26% (26 aa)

EAPYS---LAASDITPT------SATLSWLPPDSDGGSPILGYTLETKDRFSSRWTKVNKGLLQETSFKVTNLEEN----NEYVYRVIAENK--AGPS
 .|     | ..|.|.|      |.|||| ||       |.||.                       ..||.|...     ||..||.|.|.  ||..
GPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 100-183 24 1.2e-16 62.5 SMART 1-69 (69) Show / Hide
Range on Protein: 100-183
Range on HMM: 1-69/69
Sequence Identity: 24% (24 aa)

PEAPGN---VVAKDTTPT------STVITWREPSFDGGSPITGYTVEMKEPYSTRWTPANKEPIEETTFLVKRLKEN----ENYQFRVVAHNL--AGPG
| .|.|   ....|.|.|      | ...| .|       |.||.                       . |. ||..     .|.|||.|.|   ||.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 396-479 26 1.8e-21 78.6 SMART 1-69 (69) Show / Hide
Range on Protein: 396-479
Range on HMM: 1-69/69
Sequence Identity: 26% (26 aa)

PSAPGV---PKASNITPT------SVTLSWTAPDSDGGSPITEYILESKDKYSSKFSPVTRDTVTDLTFTVKNLKEN----GEYQFRVIAQNK--AGPS
|..|.    ......|.|      ||||||..|       |..|.                       .||..||..     ||.|||.| |.  ||..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 295-378 23 3e-18 67.87 SMART 1-69 (69) Show / Hide
Range on Protein: 295-378
Range on HMM: 1-69/69
Sequence Identity: 23% (23 aa)

PSAPSK---PEVTDIQKT------SAVVTWTAPKNDGGSQVTGYTVEKREKGRDQWVRVNRKPVTETTMKVPDLVEK----NNYEFRVIAENR--AGPG
|..|.    ..|||. .|      |....|..|       ..||.                        .|..|..      .|||||.|.|.  ||.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 200-282 27 1.9e-16 61.89 SMART 1-69 (69) Show / Hide
Range on Protein: 200-282
Range on HMM: 1-69/69
Sequence Identity: 27% (27 aa)

PKPPTP---PEVKRLSPT------SVQLNWSAPTSDGGSEVTAYIVEKKDKSGRWTPVTSDSIEDTSFTVKGLKEG----EDVEFRVSAVNK--AGTG
| ||.    ..|.  ..|      ||.| |..|       .. |.                      .||.|||.|       ||||.|||.  || |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

IG TTN.AA IG 258-488 5 0.340546 1.33 SMART 1-58 (58) Show / Hide
Range on Protein: 258-488
Range on HMM: 1-58/58
Sequence Identity: 5% (12 aa)

FTVKGLKEGEDVEFRVSAVNKAGTGKPSEVTVIAAKPPSAPSKPEVTDIQKTSAVVTWTAPKNDGGSQVTGYTVEKREKGRDQWVRVNRKPVTETTMKVP
      ||||.|...  .                                     ..|.                                         
PP-VTVKEGETVTLTC-VS-----------------------------------QIWWY-----------------------------------------

DLVEKNNYEFRVIAENRAGPGEASDASASFTAKAPFDEPSAPGVPKASNITPTSVTLSWTAPDSDGGSPITEYILESKDKYSSKFSPVTRDTVTDLTFTV
                                                                                                 .|.
-------------------------------------------------------------------------------------------------LTI

KNLKEN-----GEYQFRVIAQNKAGPSEP--SRETKVV
 |....     |.|. ..     .|  .   . . .| 
-NVQPEDSQQHGTYYCQAT----HGQYWSIQGTTLTVQ

FN3 TTN.AA FN3 496-578 24 8.8e-15 56.35 SMART 1-69 (69) Show / Hide
Range on Protein: 496-578
Range on HMM: 1-69/69
Sequence Identity: 24% (24 aa)

PQAPSA---PEVRRLSPT------SIQLDWTPPFADGGSDITGYIIEKKEKSGRWTPVSSDSVDGTTFTVKGLPDD----EDVEFRISAVNK--AGQS
| .|.    ..|.  ..|      |..| |.||       |.||.                      .||.||  .       |||..|||.  ||..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 591-674 27 8.4e-20 73.03 SMART 1-69 (69) Show / Hide
Range on Protein: 591-674
Range on HMM: 1-69/69
Sequence Identity: 27% (27 aa)

PGAPGR---PEVSDINKT------SATVTWKPSSSDGGSTITGYIVEKREKGRDRWVPVNRKPINAVTMKVTDLTEK----TDYEFRVIAENR--IGQG
||.|..   ..|.|...|      |.|..|||        |.||.                        .||.|..     | |||||.|.|.   |.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 692-775 25 3.3e-18 67.72 SMART 1-69 (69) Show / Hide
Range on Protein: 692-775
Range on HMM: 1-69/69
Sequence Identity: 25% (25 aa)

PTAPGA---PKASDITPT------SLTLTWTPPTDDGGSPITNFIIEWKDKFSTRFTIFKKDLFVELTFKVTGLKDK----TEYTFRIIAENK--EGQS
| .|.    ....|.|.|      |.||.|.||           |....                   ..|||||      |||.||..|.|.   |..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-----------IVGYR-------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 792-873 29 5.9e-18 66.89 SMART 1-69 (69) Show / Hide
Range on Protein: 792-873
Range on HMM: 1-69/69
Sequence Identity: 29% (29 aa)

PQEPSA---PEVKRLSPT------SVELSWTPPRSDGGADITGYILEKKDKSGRWTPVTDSVDGTSFTVKGLKEG----ENVEFRVSAVNK--AGQS
|  |.    ..|.  ..|      ||.|||.||       |.||.                     .||.|||.|     . ||||.|||.  ||..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 886-968 28 1.1e-18 69.38 SMART 1-69 (69) Show / Hide
Range on Protein: 886-968
Range on HMM: 1-69/69
Sequence Identity: 28% (28 aa)

PGPPGM---PEVSDVDKN------CVTLNWTPPTSDGGSTIIGYTVEKREKGRSWIRVNRTLVNETTMTVSDLVEK----NDYEFRVIAENK--VGPG
||||.    ..|.||...       ||| |.||       |.||.                       ||..|..       |||||.|.|.  .|.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 986-1069 28 4.5e-20 73.92 SMART 1-69 (69) Show / Hide
Range on Protein: 986-1069
Range on HMM: 1-69/69
Sequence Identity: 28% (28 aa)

PAAPDA---PEPSNVTPT------TATLTWTPPKRDGGSPITGYILEMKDRFATRWTQVNTDSMTEVTCTLKTLKEG----TEYQFRVIAVNK--AGQS
| .|     .. ..||.|      ..||.|.||       |.||.                       .|.. ||.|    |||.|||.|||.  ||..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 1086-1169 24 4.4e-17 63.98 SMART 1-69 (69) Show / Hide
Range on Protein: 1086-1169
Range on HMM: 1-69/69
Sequence Identity: 24% (24 aa)

PGAPST---PTITKATPN------SISLAWRPPKVNGGSRVTGYYIEMKDEYRPRWSPINKVAIKDTDYKVMDLTKN----EKYYFRVKAENK--AGQG
||.|.    ...|  |..      |..| | ||       ..||                        |.| .|. .     .| |||.|.|.  ||.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 1186-1269 25 3.2e-15 57.82 SMART 1-69 (69) Show / Hide
Range on Protein: 1186-1269
Range on HMM: 1-69/69
Sequence Identity: 25% (25 aa)

PDAPTI---DDVSRISET------SAKIKWTPPSNDGGAEISGYIIEKKDRLAVKWSPVIEDTLDNTSFTVKNLREG----EDVEFRVSAVNK--AGTG
|..|.      |. ...|      |. ..|.||       | ||.                       .||..|..|       ||||.|||.  || |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 1282-1365 24 4.2e-16 60.75 SMART 1-69 (69) Show / Hide
Range on Protein: 1282-1365
Range on HMM: 1-69/69
Sequence Identity: 24% (24 aa)

PGPPGV---PEASNIDKI------SATLTWTPPESDGGSKVTGYIVEKRERGLDRWMKVNRAPVKDVTLKVLDLTEK----KHYEFRVTAENK--AGLG
||||.    ........       |.||.|.||       ..||.                        .| .|..     . |||||.|.|.  || |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 1413-1496 29 2.1e-20 75.02 SMART 1-69 (69) Show / Hide
Range on Protein: 1413-1496
Range on HMM: 1-69/69
Sequence Identity: 29% (29 aa)

PGPPGT---PEVSDVDKT------SVTLTWTPPKLDGGSKVIGYIVEKREKGRDRWVRINRSPVREVTMSITDLVEK----NEYEFRVIAENK--VGPG
||||.    ..|.||..|      ||||.|.||       ..||.                         .|.|..      ||||||.|.|.  .|.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 1614-1697 27 2.5e-17 64.79 SMART 1-69 (69) Show / Hide
Range on Protein: 1614-1697
Range on HMM: 1-69/69
Sequence Identity: 27% (27 aa)

PEAPSP---PSIERISPT------SVKLAWSPPNSDGGDKVTGYIIEKKDRFSGRWTPVTKDIIDDTNFTIKGLKEG----EEAEFRVVAVNK--AGSG
| .|.    .... ...|      || | |.||       ..||.                       .|..|||.|     | ||||.|||.  ||.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 1514-1597 29 7.7e-17 63.19 SMART 1-69 (69) Show / Hide
Range on Protein: 1514-1597
Range on HMM: 1-69/69
Sequence Identity: 29% (29 aa)

PSPPKS---LKATDLTPI------SVTLNWSAPLSNGGSPIVGYTIEMKDKFSTRWTNVSEHMVTTLSLNVPNLKEK----NDYQFRVIAHNK--AGPG
|.||.    |..|| |.       |||| |..|       ||||.                         |..||.       |.|||.|.|.  ||.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

IG TTN.AA IG 1376-1705 2 0.236078 2.71 SMART 1-58 (58) Show / Hide
Range on Protein: 1376-1705
Range on HMM: 1-58/58
Sequence Identity: 2% (10 aa)

KPPYGLPEDEDVEFRISAVNKAGAGSPSNTVVIAFKPPGPPGTPEVSDVDKTSVTLTWTPPKLDGGSKVIGYIVEKREKGRDRWVRINRSPVREVTMSIT
 | .   | |.|...  .                                    ...|.                                         
PP-VTVKEGETVTLTC-VS-----------------------------------QIWWY-----------------------------------------

DLVEKNEYEFRVIAENKVGPGEPSSPSERIVAKAPYEVPSPPKSLKATDLTPISVTLNWSAPLSNGGSPIVGYTIEMKDKFSTRWTNVSEHMVTTLSLNV
                                                                                                    
----------------------------------------------------------------------------------------------------

PNLKEKNDYQFRVIAHNKAGPGQPSEPISVTAKFPFNAPEAPSPPSIERISPTSVKLAWSPPNSDGGDKVTGYIIEKKDRFSGRWTPVTKDIIDDTNFTI
                                                                                                 .||
-------------------------------------------------------------------------------------------------LTI

KGLKEGEE---AEFRVVAVNKAGSG-KPSQTTVL
 ....  .   .... .| .. ... .. . ||.
-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ

FN3 TTN.AA FN3 1710-1791 31 1.6e-20 75.41 SMART 1-69 (69) Show / Hide
Range on Protein: 1710-1791
Range on HMM: 1-69/69
Sequence Identity: 31% (31 aa)

PGPPES---PSISDVKQT------SVTLSWTPPESDGGSKIIGYIVEKKDMGRWVKVNRSPVRETTMVVTDLVEK----SEYEFRVMAENK--VGVG
||||.    ....||  |      ||||||.||       |.||.                      .||.|..     .|||||| |.|.  .| |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 1809-1890 22 1.3e-17 65.72 SMART 1-69 (69) Show / Hide
Range on Protein: 1809-1890
Range on HMM: 1-69/69
Sequence Identity: 22% (22 aa)

PDKPDQ---PDVTDIDKN------EMTVKWSSPYSDGGSKITGYIVEMKEPYSSRWSQVTKTTDFTFKVTRLTEG----KDYQFRIIAENK--AGQS
|. |     . |||....       .|..|. |       |.||.                     ..|| |..|    . |.||..|.|.  ||..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 1908-1991 25 3.2e-12 47.85 SMART 1-69 (69) Show / Hide
Range on Protein: 1908-1991
Range on HMM: 1-69/69
Sequence Identity: 25% (25 aa)

PGAPDT---PELTDIKDF------SLTVKWLAPTSDGGSPILGYFVEQKDQFSTRWQRVKSSPILDLKFTVTNVQDD----AECEFHVIAINK--AGEG
||.|     ...||. .       |.|..| .|       |.||                        .|||. . .     | || |.|.|.  ||||
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 2004-2087 25 1.3e-14 55.75 SMART 1-69 (69) Show / Hide
Range on Protein: 2004-2087
Range on HMM: 1-69/69
Sequence Identity: 25% (25 aa)

PGPPGT---PEVYNPSDK------SVDLRWTPPTEQGGTRIIGYFIEKCEVGKDNWVRINRSSIREANYVVGDLTLN----CRFKFRVCAENR--AGVG
||||.    ..| . ..       || |.|.||       |.||                        |.| .|. .     . .||| |.|.  || |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 2105-2186 26 4e-20 74.09 SMART 1-69 (69) Show / Hide
Range on Protein: 2105-2186
Range on HMM: 1-69/69
Sequence Identity: 26% (26 aa)

PESPDT---PKISDVTND------SMVISWQPPYSDGGSKVTEYIIEKKEPYSSKWVPVTKTRDLSYKITGLKEN----GDYEFRVAAVNK--AGAS
| .|     ....|||..      |...||.||       ...|.                     |..||||..      |||||.|||.  || .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 2204-2287 27 7.1e-16 59.99 SMART 1-69 (69) Show / Hide
Range on Protein: 2204-2287
Range on HMM: 1-69/69
Sequence Identity: 27% (27 aa)

PSQPHS---LKIADVSPT------SLTLEWSEPDSDGGDNVSGYIIEKKDRFSPRWTPVNQTAISDTKFKVTGLKDG----QDCEFRVVAKNK--AGAS
|. |     |.. ||..|      |.||.|..|       . ||.                       ..||||| |    .  ||||.|.|.  || .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 2300-2383 27 5.2e-20 73.71 SMART 1-69 (69) Show / Hide
Range on Protein: 2300-2383
Range on HMM: 1-69/69
Sequence Identity: 27% (27 aa)

PDAPSR---PDIKKVTEN------SVTLSWSPPESDGGSPVTSYIVERREPDRDYWVKATRYPITDTTFTVQDLTPK----HKYEFRVIAENK--AGLG
|..|..   . .. ||..      ||||||.||       ...|.                       .|| .|.|     ..|||||.|.|.  || |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 2401-2482 30 3.3e-20 74.37 SMART 1-69 (69) Show / Hide
Range on Protein: 2401-2482
Range on HMM: 1-69/69
Sequence Identity: 30% (30 aa)

PDVPVD---LDVTNITKN------SAELFWNPPMDDGGSPITNYVVEMKDKFGVRWTSLGKPTKTSFKVTNLKTG----SEYEFQVRAENK--AGEG
|. | .   | ||..|..      |..| |.||       |..|.                     ..||.|| |    .||||.|||.|.  ||||
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 2500-2583 26 2.4e-20 74.83 SMART 1-69 (69) Show / Hide
Range on Protein: 2500-2583
Range on HMM: 1-69/69
Sequence Identity: 26% (26 aa)

PDAPEK---PEPSSLTET------SVTLTWTPPASDGGSQITGYIVEKKEDFMTRWVNATRDATHKTTLTLNDLREG----SEYTFRVIAENK--AGQS
|..|.    .. .. |.|      ||||.|.||       |.||.                        |. .|..|    .||.|||.|.|.  ||..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 2601-2684 27 6.9e-20 73.32 SMART 1-69 (69) Show / Hide
Range on Protein: 2601-2684
Range on HMM: 1-69/69
Sequence Identity: 27% (27 aa)

PDTPGS---PEASNITET------SATLNWKAPTSDGGSPITNYEIEKREGASGRWTTCNRFDVSETSFTVRDLRAG----HEYSFRVAAVNK--AGSG
|. |.    ......|.|      |.|| ||.|       |..|.                       .||..|..|    .||.|||.|||.  ||.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 2702-2783 27 1.1e-16 62.64 SMART 1-69 (69) Show / Hide
Range on Protein: 2702-2783
Range on HMM: 1-69/69
Sequence Identity: 27% (27 aa)

PEAPSA---PVIEEVTAN------SVKLSWEPPRLDGGSHIIDYVVEKKDAFSIRWTEVNRTPETTFTVPKLKEG----DAVQFRVTAVNK--AGPG
| .|.    .....||..      || |||.||       |. |.                     .||. ||.|       .|||.|||.  ||.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 2801-2884 26 1.2e-16 62.6 SMART 1-69 (69) Show / Hide
Range on Protein: 2801-2884
Range on HMM: 1-69/69
Sequence Identity: 26% (26 aa)

PEAPSQ---PTAVEVDAV------SITVRWSAPKNDGGSRITNYILEMKEQFSSFWKRVSTKESSELTYQVTGLKEN----QTLEFRVIAVNK--AGEG
| .|.    .....|..       |.|..|..|       |..|.                       | |||||..    .. ||||.|||.  ||||
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 2902-2985 22 1.5e-14 55.59 SMART 1-69 (69) Show / Hide
Range on Protein: 2902-2985
Range on HMM: 1-69/69
Sequence Identity: 22% (22 aa)

PSAPGA---PDVSNVKAT------SMAVTWTKSISDGGSPITGYVLEKCDVSTGRWVPVNRVPLRETSLVVDQLREK----SEYCFRVVAHNV--AGES
|..|.    . |..| .|      |. ..|..        |.||.                        .|. |..     .|| |||.|.|   |||.
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 3104-3186 24 1.8e-17 65.32 SMART 1-69 (69) Show / Hide
Range on Protein: 3104-3186
Range on HMM: 1-69/69
Sequence Identity: 24% (24 aa)

PSAPGT---PKISDITGT------SLVLTWTPPSSDGGTEITNFIIELRDRYGRWTRVNRTQVLKTGFNVMNLSEG----DSYEFRVTAENK--MGVG
|..|.    ....|.| |      |..|.|.||           |.. |                  . | .|..|      |||||.|.|.   | |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-----------IVGYR------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 3003-3086 25 8.6e-16 59.71 SMART 1-69 (69) Show / Hide
Range on Protein: 3003-3086
Range on HMM: 1-69/69
Sequence Identity: 25% (25 aa)

PDAPAK---PDITNIDAK------QITLAWSPPWSDGGSPIIGYQIEKKDRYSVRWTRATRETIHDMQYTLRELTEG----GEVEFRVAAENK--AGVG
|..|     . .|....       ..|| |.||       |.||.                       ||.. |..|     | ||||.|.|.  || |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

IG TTN.AA IG 3062-3198 7 0.28886 1.95 SMART 1-58 (58) Show / Hide
Range on Protein: 3062-3198
Range on HMM: 1-58/58
Sequence Identity: 7% (10 aa)

YTLRELTEGGEVEFRVAAENKAGVGPFSDTTGTVIAKSPFDVPSAPGTPKISDITGTSLVLTWTPPSSDGGTEITNFIIELRDRYGRWTRVNRTQVLKTG
    .  ||. |...  ..                                         ..|.                                    
PP-VTVKEGETVTLTC-VS----------------------------------------QIWWY------------------------------------

FNVMNLSEGDS---YEFRVTAENKMGVGKPSD-STQKVTAK
... |... ||    ... .|.     |. .   . ..| .
LTI-NVQPEDSQQHGTYYCQAT----HGQYWSIQGTTLTVQ

FN3 TTN.AA FN3 3204-3287 27 1.2e-19 72.57 SMART 1-69 (69) Show / Hide
Range on Protein: 3204-3287
Range on HMM: 1-69/69
Sequence Identity: 27% (27 aa)

PAAPNE---PQISNVTAD------SATLTWSPPRDDGGSSITGYFIEKKDKFSPRWTRVNHDAVTDTKFTVPALVPG----EEYQFRVVAQNK--AGAS
| .|     .....||..      |.||.|.||       |.||                        .||. |.||     ||.|||.| |.  || .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 3305-3388 30 5.5e-21 76.97 SMART 1-69 (69) Show / Hide
Range on Protein: 3305-3388
Range on HMM: 1-69/69
Sequence Identity: 30% (30 aa)

PGAPGA---PETSNVTET------TLTLTWTPPFSDGGSRITGYYVEKKDRMSLRWSPVNFESTEDTKLKVTGLTEG----TEYEFRVVAEND--AGRS
||.|.    .. ..||.|      ..||.|.||       |.||                         .||||..|    |||||||.|.|.  ||..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 3406-3489 26 2.7e-17 64.69 SMART 1-69 (69) Show / Hide
Range on Protein: 3406-3489
Range on HMM: 1-69/69
Sequence Identity: 26% (26 aa)

PSAPGT---PSISDISST------NMTLRWAPPESDGGTVIITFIVERREQFSTRWVQISRFDFTETTFSVTGLKDG----NDYEFRVAAKNK--IGIG
|..|.    ....|..||       .||.| ||       |....                       . ||||| |      |||||.|.|.   |.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 3507-3590 26 3.5e-18 67.63 SMART 1-69 (69) Show / Hide
Range on Protein: 3507-3590
Range on HMM: 1-69/69
Sequence Identity: 26% (26 aa)

PESPST---PDVSNITGE------SMTLNWTAPRTDGGSPITGYVIEKREPGRSGWTVVNRSPITSLSCVVPNLRQG----AEYEFRVIAENK--AGLG
| .|.    . |...|        |.|| |..|       |.||.                       ..|..|. |     ||||||.|.|.  || |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 3608-3690 30 4.1e-18 67.41 SMART 1-69 (69) Show / Hide
Range on Protein: 3608-3690
Range on HMM: 1-69/69
Sequence Identity: 30% (30 aa)

PGIPDQ---PEVEDVTAT------TITISWSPPSYDGGSKITGYTIESKSDATMRWVKIESTVPDTTYTAARLKEL----SEYQFRVAAINK--AGRG
|| |     ..|.|||.|      ..|.||.||       |.||.                      ||   ||.     .||.|||.|.|.  ||.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 3707-3791 29 9e-19 69.61 SMART 1-69 (69) Show / Hide
Range on Protein: 3707-3791
Range on HMM: 1-69/69
Sequence Identity: 29% (29 aa)

PPPPPDA--PDVYNITPT------SAALTWSTPRQDGGSPITGYVIDKKDKYSTRWVKADEVPAGTTDFTIKGLQAG----NDYEFRVSAVNA--AGVG
|.|||.   . | ..|.|      |. |.|. |       |.||.                       .|..||..|      |||||.|||.  || |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 3809-3892 26 9.7e-21 76.14 SMART 1-69 (69) Show / Hide
Range on Protein: 3809-3892
Range on HMM: 1-69/69
Sequence Identity: 26% (26 aa)

PDAPSP---PSVSDITPS------SMTLSWEPPASDGGSTVTGYIVEKRECPVGRWVPVNRAPVKETTFKVNDLSED----RKYEFRVSAENA--AGVG
|..|.    ..|.|.|..      |.||||.||       ..||.                       ..| .|...     .|||||.|.|.  || |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 3910-3993 26 1.6e-18 68.76 SMART 1-69 (69) Show / Hide
Range on Protein: 3910-3993
Range on HMM: 1-69/69
Sequence Identity: 26% (26 aa)

PSAPGR---PTATNVDST------ELVLEWTAPVADGGSAITNYVIEARDKFGLRWSKINRQTVTDTTFKVTGLKPN----DEYQFRVIAENK--VGLG
|..|..   ...|.|.||       ..|.|..|       |..|.                       ..||||||.     ||.|||.|.|.  .| |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 4011-4094 25 3.7e-18 67.55 SMART 1-69 (69) Show / Hide
Range on Protein: 4011-4094
Range on HMM: 1-69/69
Sequence Identity: 25% (25 aa)

PDAPES---VQVTGTTAS------SASLEWSPPFSDGGSPVTGYFVERKDQYSARWTRVNRVPVTETNMVVGDLKEG----LQYQFRVCAENR--AGIG
|..|.    ..|| .|..      |..|.|.||       ..||                         .| .||.|     .|.||| |.|.  ||.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 4112-4193 23 4.4e-19 70.64 SMART 1-69 (69) Show / Hide
Range on Protein: 4112-4193
Range on HMM: 1-69/69
Sequence Identity: 23% (23 aa)

PSAPLE---PTIASITAD------SATLTWTAPTRDGGSAVTGYIVERKDPYTARWTPIERCTDTNCKISGLKEG----NEYQFRVLATNK--AGQS
|..|     ... ..|..      |.||.|..|       ..||.                     ....|||.|     ||.||| | |.  ||..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 4211-4294 29 3.3e-18 67.75 SMART 1-69 (69) Show / Hide
Range on Protein: 4211-4294
Range on HMM: 1-69/69
Sequence Identity: 29% (29 aa)

PEAPSK---PQVAEVKAT------SVTLKWRPPGSDGGSPVTGYVVQKKERLALRWTPVNTTPVGDTIFTVTGLTQK----SEYEFRVVAANK--KGFG
| .|.    ..| .| .|      ||||.| ||       ..||.                       .|||||.      .||||||.| |.  .| |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 4309-4392 32 1.7e-17 65.39 SMART 1-69 (69) Show / Hide
Range on Protein: 4309-4392
Range on HMM: 1-69/69
Sequence Identity: 32% (32 aa)

YGRPSP---PVVTDFTKT------SVTLQWNPPESDGGSHITGYVLEKKEAYSVRWFPCTSQSILKPEFTVKDLKEG----AQYEFRVMALNK--AGLG
 | |.    ..||| |.|      ||||.|.||       |.||.                       .||..||.|     .||||| | |.  || |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 4410-4493 20 7.8e-15 56.52 SMART 1-69 (69) Show / Hide
Range on Protein: 4410-4493
Range on HMM: 1-69/69
Sequence Identity: 20% (20 aa)

PSPPGE---PTISNITAK------SVTLNWTAPSSDGGSPVTGYTVERADRFSTRWVPVNSHPIKDTKMDIHDLPAT----GSYQFRIVACNA--AGTS
|.||.    ......|.       |||| |..|       ..||.                         ...| .       |.||..| |.  || .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

I-set TTN.AA I-set 4519-4599 27 1.7e-16 58.5 Pfam 10-92 (92) Show / Hide
Range on Protein: 4519-4599
Range on HMM: 10-92/92
Sequence Identity: 27% (23 aa)

MVVRVGATFNLDVPFKATPKPTVKWTKDGSTLQA-SSRIKIDTTD-RDTIVTIKNCVREDEGSFKLDVSNTAGSDAITIRVQV
..|..| | ....  . .|.|.| |.|||. |.  |.|.... ..  ..  ||.|. ..|||. .  ..| .|..  |....|
VEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IG TTN.AA IG 4516-4600 14 7e-06 26.78 SMART 1-58 (58) Show / Hide
Range on Protein: 4516-4600
Range on HMM: 1-58/58
Sequence Identity: 14% (13 aa)

HDTMVVRVGATFNLDVPFKATPKPTVKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDE---GSFKLDVSNTAGSDAI--TIRVQVL
   ..|..| | .|   ..     ...|.                       || |  .||.   | .   ..  .|..    .....|.
PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

IGc2 TTN.AA IGc2 4522-4589 26 0.001133 10.1 SMART 1-56 (56) Show / Hide
Range on Protein: 4522-4589
Range on HMM: 1-56/56
Sequence Identity: 26% (18 aa)

RVGATFNLDVPFKATPKPTVKWTKDGSTLQASSRIKIDTTDRDTIVTIKNCVREDEGSFKLDVSNTAG
. | .. |  |  . | |...|.| |. |.            .  .||||  .||.|     ..| .|
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG

FN3 TTN.AA FN3 4603-4686 26 2.1e-17 65.03 SMART 1-69 (69) Show / Hide
Range on Protein: 4603-4686
Range on HMM: 1-69/69
Sequence Identity: 26% (26 aa)

PEQPRGP--LVAKDIGST------DLFLSWKEPADNGGSPITHYIIERREEDRTSWTRLTTRALDTTVRVTSLQEG----ASYVFRVFAVNK--IGDS
|  |..|  |...|..||       . ||||.|       |..|.                      ..|| |..|      |.||| |||.   | .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

I-set TTN.AA I-set 4805-4895 32 3.4e-19 67.63 Pfam 1-92 (92) Show / Hide
Range on Protein: 4805-4895
Range on HMM: 1-92/92
Sequence Identity: 32% (30 aa)

PKFSGRFDEPIMAKVGESFRIEVPYTGIPTPAVTWSFDGRPLKP-SAHIRIDTSN-RASTITVKNVEKANGGRYTINLKNTAGAESLDVEVRV
|||. .   .. ...||. | |.  || |.| |.|  ||.||.| | ..... ..   .| |..||...  | ||.  .| .|  . ..|. |
PKFTQKP-KDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

FN3 TTN.AA FN3 4704-4787 29 1.9e-17 65.2 SMART 1-69 (69) Show / Hide
Range on Protein: 4704-4787
Range on HMM: 1-69/69
Sequence Identity: 29% (29 aa)

PEAPSK---PLVTNVTSD------SVTLEWHSPKSDGGAPISGYIIEKKETSSNYWSKVTTVSSGVTSHRIPRLMRG----EEYEFRVSAENR--AGPG
| .|.    . ||.|||.      ||||.|  |       | ||.                       .... |  |     ||||||.|.|.  ||.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

IG TTN.AA IG 4812-4896 12 9e-06 26.5 SMART 1-58 (58) Show / Hide
Range on Protein: 4812-4896
Range on HMM: 1-58/58
Sequence Identity: 12% (11 aa)

DEPIMAKVGESFRIEVPYTGIPTPAVTWSFDGRPLKPSAHIRIDTSNRASTITVKNVEKANG---GRYTINLKNTAGAESL--DVEVRVF
 . . .|.||. ...  ..      ..|.                      .|. ||....    | |.   .  .|  .    ....|.
PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

IGc2 TTN.AA IGc2 4818-4885 30 0.001155 10.02 SMART 1-56 (56) Show / Hide
Range on Protein: 4818-4885
Range on HMM: 1-56/56
Sequence Identity: 30% (21 aa)

KVGESFRIEVPYTGIPTPAVTWSFDGRPLKPSAHIRIDTSNRASTITVKNVEKANGGRYTINLKNTAG
. |.|.... | || |.| ..| . | ||              .| |.|||...  |.||    | .|
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG

V-set TTN.AA V-set 4757-4895 9 1.028881 4.29 Pfam 1-128 (128) Show / Hide
Range on Protein: 4757-4895
Range on HMM: 1-128/128
Sequence Identity: 9% (17 aa)

SSGVTS--HRIPRLMRGEEYEFRVSAENRAGPGPASTPSAPIRAEDTTVLPKFSGRFDEPIMAKVGESFRIEVPYT-GI----PTPAVTWSFDGRPL---
.| ||   .|.  .                                             ......|.| ...  |. .     ..  ..|... .|.   
QSQVTQHPPRGC-PW--------------------------------------------WVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQ-QPPGQK

------------------------KPSAHIRIDTSNRASTITVKNVEKANGGRYTINLKNT-AGAESLDVEVRV
                        | . ..  ..|.   ..| .|.. .  | |.   .|   .     ....|
PQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWNCNEDYFGHGTRLTV

FN3 TTN.AA FN3 4899-4983 29 4.6e-20 73.89 SMART 1-69 (69) Show / Hide
Range on Protein: 4899-4983
Range on HMM: 1-69/69
Sequence Identity: 29% (29 aa)

PGPPRGP--LEMSNVSES------TVTLSWSPPSDDGGSRIFTYVVQKRGEIETKWKHVNKDYIIDLTYKVTGLKEN----KKYQFRVLAENQ--YGQS
||||..|  |. ..|...      .|||||.||       | .|.                       |.|||||..    ..|.||| |.|   .|..
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 5000-5083 28 1.1e-17 66.0 SMART 1-69 (69) Show / Hide
Range on Protein: 5000-5083
Range on HMM: 1-69/69
Sequence Identity: 28% (28 aa)

PDPPSA---PKVTNIIGD------SVTVGWTPPSNDGGAPVTGYVVEMRQTTSPRWIKATLTPTPDTTFRASRLIRG----TEYEFRVCAVNR--AGTG
|.||.    ..||..  .      |||. |.||       ..||.                       .. . |  |    ||||||| |||.  || |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

I-set TTN.AA I-set 5128-5193 29 1.2e-17 62.38 Pfam 25-92 (92) Show / Hide
Range on Protein: 5128-5193
Range on HMM: 25-92/92
Sequence Identity: 29% (20 aa)

KATPTPTVSWTQNGDTVQK-SNRITIDSNN-YGTTLTARTAERTDSGDYVIRASNKAGEDTVTVTVNV
. .|.|.|||. .|  ..  |.|. .. .. . .||| . ... |.| | ..|.|..||...|....|
TGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IG TTN.AA IG 5110-5194 15 5.4e-07 30.49 SMART 1-58 (58) Show / Hide
Range on Protein: 5110-5194
Range on HMM: 1-58/58
Sequence Identity: 15% (14 aa)

EKVITIRAGHTFRIDIPYKATPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTDS---GDYVIRASNKAGEDTV--TVTVNVV
 . .| ..| | ..   ..     ...|.                      ||   ... ||   |.|. .|.  .|...   ..|. | 
PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

IGc2 TTN.AA IGc2 5116-5183 23 0.000803 11.53 SMART 1-56 (56) Show / Hide
Range on Protein: 5116-5183
Range on HMM: 1-56/56
Sequence Identity: 23% (16 aa)

RAGHTFRIDIPYKATPTPTVSWTQNGDTVQKSNRITIDSNNYGTTLTARTAERTDSGDYVIRASNKAG
. | ....  |  . |.|...|.  |  ..           .. ||| . ... ||| |. .|.|..|
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG

FN3 TTN.AA FN3 5197-5280 27 2.3e-18 68.23 SMART 1-69 (69) Show / Hide
Range on Protein: 5197-5280
Range on HMM: 1-69/69
Sequence Identity: 27% (27 aa)

PSPPQGP--LALVKLGSN------EVTLSWSRPRDDGGSPITGYVLEKREGGYGSWTNVSSKIPDTTFRVTKLTED----REYQFRVRAENN--LGVS
|.||..|  | ..  .|.       |||||..|       |.||.                      ..|| |...     ||.|||||.|    | .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 5297-5382 24 2.2e-17 64.98 SMART 1-69 (69) Show / Hide
Range on Protein: 5297-5382
Range on HMM: 1-69/69
Sequence Identity: 24% (25 aa)

PDQPGK---IKVDTIQSD------SVSLTWSRPQRDGGAPVTGYIVEKRERGQPEAGWNRTSYKPVMDTTIRVPRLSEG----KEYEFRVSAVNK--AGM
|. |.    ..|  . |.      ||.|.|..|       ..||.                          .|. |..|    .||||||.|||.  || 
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-------------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGE

S
.
G

I-set TTN.AA I-set 5412-5492 22 2.5e-17 61.33 Pfam 10-92 (92) Show / Hide
Range on Protein: 5412-5492
Range on HMM: 10-92/92
Sequence Identity: 22% (19 aa)

ITVRAGTLFHLDVPISGTPTPTVAWLMDEKQVDD-GRRIKASTTT-YSAVLTNKDARRTDSGTYTIKISNKAGTDTATIRVAV
..|. |    ... ..|.|.|.| |. |....   ..|.. . .  . . || ... . |.|.||.. .|..|....|... |
VEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IG TTN.AA IG 5409-5493 16 0.000459 20.75 SMART 1-58 (58) Show / Hide
Range on Protein: 5409-5493
Range on HMM: 1-58/58
Sequence Identity: 16% (15 aa)

RDVITVRAGTLFHLDVPISGTPTPTVAWLMDEKQVDDGRRIKASTTTYSAVLTNKDARRTDS---GTYTIKISNKAGTDTA--TIRVAVL
   .||..|    |   .|     .. |.                      ||  .... ||   |||.   .  .|....  .... |.
PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

IGc2 TTN.AA IGc2 5415-5482 25 0.000672 12.27 SMART 1-56 (56) Show / Hide
Range on Protein: 5415-5482
Range on HMM: 1-56/56
Sequence Identity: 25% (17 aa)

RAGTLFHLDVPISGTPTPTVAWLMDEKQVDDGRRIKASTTTYSAVLTNKDARRTDSGTYTIKISNKAG
. |. . |  | .| |.|.. |.  .....           ..  || |.... |||.|| . .|..|
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG

V-set TTN.AA V-set 5447-5492 21 0.002183 13.51 Pfam 82-128 (128) Show / Hide
Range on Protein: 5447-5492
Range on HMM: 82-128/128
Sequence Identity: 21% (10 aa)

RRIKASTTTYSAVLTNKDARRTDSGTYTIKISNK-AGTDTATIRVAV
... .... ... || ..... |||||.  ..|   ..  . .|. |
VTFSGNPSKNDFSLTISNLQPSDSGTYYCAVWNCNEDYFGHGTRLTV

FN3 TTN.AA FN3 5496-5579 32 2.8e-19 71.28 SMART 1-69 (69) Show / Hide
Range on Protein: 5496-5579
Range on HMM: 1-69/69
Sequence Identity: 32% (32 aa)

PSAPEGP--IKVTSITCD------SVTLAWEPPKDDGGADITGYILERREPDQFRWTRVTSTLSSPRYAVTGLKDG----RSYLFRVRAVSK--YGES
|..|..|  ..||..| .      |||| |.||       |.||.                      | ||||| |      | ||||||..  .||.
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 5597-5680 28 4.5e-19 70.61 SMART 1-69 (69) Show / Hide
Range on Protein: 5597-5680
Range on HMM: 1-69/69
Sequence Identity: 28% (28 aa)

PPAPGV---PKASNVRDD------SITLSWQPPHSDGGAEIHNYILEIKETRGTRWLRATRKQLKSPNFRVTGLSKG----REYEFRVAAENE--AGLG
|..|.    .....| ..      |.||||.||       | .|.                       ..||||. |     ||||||.|.|.  || |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

IG TTN.AA IG 5704-5783 20 1e-09 39.51 SMART 1-58 (58) Show / Hide
Range on Protein: 5704-5783
Range on HMM: 1-58/58
Sequence Identity: 20% (18 aa)

LKDVSAKAGKIVTLECRISNPNAEVKWMKDGFQIFGYDRVNEIKEGQRRAITLRNVGDRDT---GKYSCECG--KQST--SCWLSVT
 . |..|.|  |||.| .|    ...|.                      .|. ||   |.   | | |.    ...   . .|.|.
PP-VTVKEGETVTLTC-VS----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQATHGQYWSIQGTTLTVQ

I-set TTN.AA I-set 5698-5782 29 9.5e-07 25.42 Pfam 1-92 (92) Show / Hide
Range on Protein: 5698-5782
Range on HMM: 1-92/92
Sequence Identity: 29% (27 aa)

AEFVEPLKDVSAKAGKIVTLECRIS-NPNAEVKWMKDGFQIFG-YDRVNEIKEG-QRRAITLRNVGDRDTGKYSC----ECGKQSTSCWLSV
 .|. ..||| .. |. ...||... .|  .| | ||| ..    ||..   .| ..   | .||  .|.|||.|    . |...... | |
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IGc2 TTN.AA IGc2 5710-5776 25 2.7e-05 24.84 SMART 1-56 (56) Show / Hide
Range on Protein: 5710-5776
Range on HMM: 1-56/56
Sequence Identity: 25% (17 aa)

KAGKIVTLECR-ISNPNAEVKWMKDGFQIFGYDRVNEIKEGQRRAITLRNVGDRDTGKYSCECGKQST
. |  |||.|.   ||.....| |   |              .   |..||   | |.|.|.      
HEGQSVTLTCPATGNPDPNIHWYK--GQPLP----------WNWTLTIKNVTPEDSGYYTCYARNPWG

V-set TTN.AA V-set 5698-5732 21 0.251515 6.4 Pfam 1-47 (128) Show / Hide
Range on Protein: 5698-5732
Range on HMM: 1-47/128
Sequence Identity: 21% (10 aa)

AEFVEP--LK----DVSAKAGKIVTLECRIS--N----PNAEVKWMK
...|..   .     |... |. |||.|  |       .|  . |..
QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYR

I-set TTN.AA I-set 5786-5877 26 5.1e-17 60.26 Pfam 1-92 (92) Show / Hide
Range on Protein: 5786-5877
Range on HMM: 1-92/92
Sequence Identity: 26% (25 aa)

PTIDVKAYKDVVVVKTGNTLRLLVPYTGCPSPKVEWHRHDARISE-DTRTHIETRD-NRTQITIRNVVRGDTGKFSITLTNEAGQETAIIRVNV
|... |     |.|. | |.|. .  ||.| |.|.|.. .. ... . | ..  .. ...  ||.|| ..|.|| ... ||..|. .. ....|
PKFTQKP--KDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IG TTN.AA IG 5794-5878 18 3.8e-07 30.99 SMART 1-58 (58) Show / Hide
Range on Protein: 5794-5878
Range on HMM: 1-58/58
Sequence Identity: 18% (17 aa)

KDVVVVKTGNTLRLLVPYTGCPSPKVEWHRHDARISEDTRTHIETRDNRTQITIRNVVRGDT---GKFSITLTNEAGQETA--IIRVNVI
   |.|| | |..|   ..      . |.                      .|| || . |.   | .  . |  .|| ..   ... | 
PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

IGc2 TTN.AA IGc2 5800-5867 23 0.001811 8.15 SMART 1-56 (56) Show / Hide
Range on Protein: 5800-5867
Range on HMM: 1-56/56
Sequence Identity: 23% (16 aa)

KTGNTLRLLVPYTGCPSPKVEWHRHDARISEDTRTHIETRDNRTQITIRNVVRGDTGKFSITLTNEAG
. |....|  | || | | . | . . ...           ..   ||.|| ..| |. . . .|..|
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG

V-set TTN.AA V-set 5787-5877 13 0.054158 8.7 Pfam 1-128 (128) Show / Hide
Range on Protein: 5787-5877
Range on HMM: 1-128/128
Sequence Identity: 13% (17 aa)

TIDVKA-YKD----VVVVKTGNTLRLLVPYTGCP----SP-KVEWHR-HDA--------------RISEDTRTHIETRDNRTQ-----------ITIRNV
 ..|..        .|.|..| ...|   |.  .    ..  . | | ...                .... .  .   .|..           .||.|.
QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL

VRGDTGKFSITLTNE-AGQETAIIRVNV
 . |.|      .|.  ..  . .|. |
QPSDSGTYYCAVWNCNEDYFGHGTRLTV

FN3 TTN.AA FN3 5881-5964 31 3.6e-19 70.93 SMART 1-69 (69) Show / Hide
Range on Protein: 5881-5964
Range on HMM: 1-69/69
Sequence Identity: 31% (31 aa)

PGPPTGP--LEITDVGRH------CVSLSWEPPKDDGGSPIQSYTVEQREANRRMWTSVSNYVSHVPFTVSGLSEK----VEYEFRVCAENI--NGVG
||||..|  |..|||...       |.|||.||       | .|.                      .||.||..      |||||| |.|   .| |
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 5982-6065 24 1.4e-18 68.92 SMART 1-69 (69) Show / Hide
Range on Protein: 5982-6065
Range on HMM: 1-69/69
Sequence Identity: 24% (24 aa)

PTPPGK---PEISNVQRD------RMTLTWSEPSHDGGKPIQGYIIERRENFSKQWNRVNRDLIKDTTFTIKGLTEG----SNYEFRISAVND--TGIG
| ||.    .....| ..       .||.|..|       | ||.                       .|..||..|    ..||||..|||.   |.|
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 6084-6165 26 4.4e-17 63.99 SMART 1-69 (69) Show / Hide
Range on Protein: 6084-6165
Range on HMM: 1-69/69
Sequence Identity: 26% (26 aa)

PTPPGA---PIIGDITAT------SVSLSWSAPSTDGGSEITHYIVERRLKGSYMWIDRTVVHDTSCSVNNLVED----KEYTFRVTAVNA--AGNE
| ||.    . . |.|.|      ||.|||..|       |..|.                     . | .|...    .||.|||.|||.  ||  
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

I-set TTN.AA I-set 6186-6275 32 3.9e-22 77.63 Pfam 1-92 (92) Show / Hide
Range on Protein: 6186-6275
Range on HMM: 1-92/92
Sequence Identity: 32% (30 aa)

PSILIEIQNAMVAEGQTGMFMCKISGAPKPKVSWMHHGRELMP-GRKHNITEDN-GVFKIVVFSVTDYETGMYTIIAKNKHGSVRSSAELLI
|.... .... | ||.|  | |...| |.|.||| . |..| | ...|..|.|. |  .  .  |.   .| ||..|.|. |.. ..||| .
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

I-set TTN.AA I-set 6281-6372 24 1.5e-17 62.08 Pfam 1-92 (92) Show / Hide
Range on Protein: 6281-6372
Range on HMM: 1-92/92
Sequence Identity: 24% (23 aa)

LSIDRHLQDLSVRAGQEIHIPVTLTYGTPKPTFTWRRHDGEELDT-RGRYRVNVVG-GIAELYVKDAEREDSGTYTLEAVNELGRHSITARVNV
 .......|. |. |. .   ..   |.|.|. .| .  |..| .   |...  .| |.. | .......|.|.||  |.|..|  . ||...|
PKFTQKPKDVEVQEGETARFECQ-VTGDPPPQVSWFKD-GQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IG TTN.AA IG 6287-6373 14 1.7e-09 38.76 SMART 1-58 (58) Show / Hide
Range on Protein: 6287-6373
Range on HMM: 1-58/58
Sequence Identity: 14% (13 aa)

LQDLSVRAGQEIHIPVTLTYGTPKPTFTWRRHDGEELDTRGRYRVNVVGGIAELYVKDAEREDS---GTYTLEAVNELGRHSI--TARVNVL
 . ..|..|. . ..   .      ...|.                       | . ....|||   |||. .|    | ..   .... |.
PP-VTVKEGETVTLTC-VS------QIWWY-----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

IG TTN.AA IG 6192-6276 17 2.7e-07 31.46 SMART 1-58 (58) Show / Hide
Range on Protein: 6192-6276
Range on HMM: 1-58/58
Sequence Identity: 17% (16 aa)

IQNAMVAEGQTGMFMCKISGAPKPKVSWMHHGRELMPGRKHNITEDNGVFKIVVFSVTDYET---GMYTIIAKNKHGSVRS--SAELLIQ
 .   | ||.|  . | .|      ..|.                      ... .|.   .   | |.  |.  ||.. |  ...| .|
PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

IGc2 TTN.AA IGc2 6297-6362 28 0.000136 18.9 SMART 1-56 (56) Show / Hide
Range on Protein: 6297-6362
Range on HMM: 1-56/56
Sequence Identity: 28% (20 aa)

EIHIPVTLTYG---TPKPTFTWRRHDGEELDTRGRYRVNVVGGIAELYVKDAEREDSGTYTLEAVNELG
..  .|||| .    | |...|..  |..|.           .  .| .|....||||.|| .| |. |
HEGQSVTLTCPATGNPDPNIHWYK--GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG

IGc2 TTN.AA IGc2 6198-6265 27 0.000764 11.74 SMART 1-56 (56) Show / Hide
Range on Protein: 6198-6265
Range on HMM: 1-56/56
Sequence Identity: 27% (19 aa)

AEGQTGMFMCKISGAPKPKVSWMHHGRELMPGRKHNITEDNGVFKIVVFSVTDYETGMYTIIAKNKHG
 |||.  . |. .|.| | ..| . | .|          .|.  .|  ... |   |.|| .| |..|
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP---------WNWTLTIKNVTPEDS--GYYTCYARNPWG

V-set TTN.AA V-set 6271-6372 16 0.226033 6.56 Pfam 1-128 (128) Show / Hide
Range on Protein: 6271-6372
Range on HMM: 1-128/128
Sequence Identity: 16% (22 aa)

AELLIQ-RPPQLSIDRHLQDLSVRAGQEIHIPVTLT--YGTPKPT--FTWRR-HDG------------------------EELDTRGRYRVNVVGGIAEL
.. . |  |. . .      ..|  || ...| ...  | .....  ..| | ..                         ..   | .  .|  .. . |
QSQVTQHPPRGC-PW----WVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSL

YVKDAEREDSGTYTLEAVN--ELGRHSITARVNV
  ......|||||.  . |  |.. .. | |. |
TISNLQPSDSGTYYCAVWNCNEDYFGHGT-RLTV

FN3 TTN.AA FN3 6376-6458 22 1.9e-14 55.21 SMART 1-69 (69) Show / Hide
Range on Protein: 6376-6458
Range on HMM: 1-69/69
Sequence Identity: 22% (22 aa)

PGPPQGP--ISIQSITNN------SATFTWTLPLDDGGAPIQRYQVSIRESNRTHWQPLGTSLLPNFTAKKLKDN----THYVLRVTAENQ--YGTS
||||..|  ... ..|..      |.| .|. |       | .|.                     .| . || .    | |. ||.|.|   .| .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

FN3 TTN.AA FN3 6476-6559 22 6.4e-20 73.43 SMART 1-69 (69) Show / Hide
Range on Protein: 6476-6559
Range on HMM: 1-69/69
Sequence Identity: 22% (22 aa)

PSAPGR---PTISNIQRD------SVHVSWTAPSSDGGSSITGYIIERRDTTSQRWIKANHEPVTTTSHTLINLRED----TEYEFRVMAENS--MGAS
|..|..   ...... ..      ||..||..|       |.||.                       .|. .|...    ||||||| |.|.   | .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR-----------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

I-set TTN.AA I-set 6579-6668 33 5.7e-27 94.04 Pfam 1-92 (92) Show / Hide
Range on Protein: 6579-6668
Range on HMM: 1-92/92
Sequence Identity: 33% (31 aa)

PQFVSKPQNAHVAEGKSVTVTCQVSGYPAPEVRWYRLGREIAH-GRKFQIGGDG-NIHTLTANQLFPEDVGEISVTVTNKGGTITDAFELNV
|.|. ||... | ||.... .|||.|.| |.| |.. |....  ....|.  || ...|||  . .|.| |. ....||..|. .  .||.|
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IG TTN.AA IG 6585-6669 24 2.4e-08 34.97 SMART 1-58 (58) Show / Hide
Range on Protein: 6585-6669
Range on HMM: 1-58/58
Sequence Identity: 24% (22 aa)

PQNAHVAEGKSVTVTCQVSGYPAPEVRWYRLGREIAHGRKFQIGGDGNIHTLTANQLFPEDV---GEISVTVTNKGGTITD--AFELNVL
|.   | || .|| || ||     ...||                      ||  .. |||    |.   ..|  .|...    ..| |.
PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

IGc2 TTN.AA IGc2 6591-6658 32 2.2e-05 25.14 SMART 1-56 (56) Show / Hide
Range on Protein: 6591-6658
Range on HMM: 1-56/56
Sequence Identity: 32% (22 aa)

AEGKSVTVTCQVSGYPAPEVRWYRLGREIAHGRKFQIGGDGNIHTLTANQLFPEDVGEISVTVTNKGG
 || ||| || ..|.|.|...||. | ...           .  |||     ||| |. . ...|. |
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG

V-set TTN.AA V-set 6579-6614 29 5.5e-05 19.03 Pfam 1-47 (128) Show / Hide
Range on Protein: 6579-6614
Range on HMM: 1-47/128
Sequence Identity: 29% (14 aa)

PQFVSK--PQ----NAHVAEGKSVTVTCQVS-GY----PAPEVRWYR
...|.   |       .|.||.||| .|..| .|    .   . |||
QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYR

I-set TTN.AA I-set 6689-6764 26 1e-20 72.84 Pfam 15-92 (92) Show / Hide
Range on Protein: 6689-6764
Range on HMM: 15-92/92
Sequence Identity: 26% (21 aa)

GEYIMLKVPFSGTPRPSIKWDRDGEDVVD-GGRFEIKATP-HDTTLIIRGITKEDAGKYSVVASNELGHDTCSIQVNI
|| . ...  .|.| |.. | .||...   . |. ....   ..||.|......|.|||..||.|..| ..|......
GETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IG TTN.AA IG 6681-6765 15 1.5e-05 25.66 SMART 1-58 (58) Show / Hide
Range on Protein: 6681-6765
Range on HMM: 1-58/58
Sequence Identity: 15% (14 aa)

RTPIHLLLGEYIMLKVPFSGTPRPSIKWDRDGEDVVDGGRFEIKATPHDTTLIIRGITKEDA---GKYSVVASNELGHDTC--SIQVNIL
   .   .|| . |.  .|     .|.|                       |.| ....||.   | |  .|.   | ...  .... ..
PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

IGc2 TTN.AA IGc2 6687-6754 29 6.5e-05 21.96 SMART 1-56 (56) Show / Hide
Range on Protein: 6687-6754
Range on HMM: 1-56/56
Sequence Identity: 29% (20 aa)

LLGEYIMLKVPFSGTPRPSIKWDRDGEDVVDGGRFEIKATPHDTTLIIRGITKEDAGKYSVVASNELG
. |. . |. | .| | |.|.| . |. .            .. || |. .|.||.|.|. .|.|. |
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG

V-set TTN.AA V-set 6677-6764 12 2.915197 2.73 Pfam 1-128 (128) Show / Hide
Range on Protein: 6677-6764
Range on HMM: 1-128/128
Sequence Identity: 12% (16 aa)

PARLRT--------PIHLLLGEYIMLKVPFSGTP----RP-SIKWDR-DGE-------------DVVD----------GGRFEIKATPH--DTTLIIRGI
.  . .        ...  .|. . |.  .| ..    .. .| | |                 .. .           ||... ..|   | .| |. .
QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL

TKEDAGKYSVVASNE-LGHDTCSIQVNI
. .| | |  ...|.  .    .... .
QPSDSGTYYCAVWNCNEDYFGHGTRLTV

FN3 TTN.AA FN3 6768-6849 23 8.3e-16 59.75 SMART 1-69 (69) Show / Hide
Range on Protein: 6768-6849
Range on HMM: 1-69/69
Sequence Identity: 23% (23 aa)

PDSPRN---LECLEITSE------AIRLAWNPPIYDGGSNISSYMVEKREVGVLTWARVISSKNTHHTVINLRSD----TQYQFRVTAFNM--YGAS
|..|.|   |.  ..||        ..| |.||       | .|                      .|| .|. .    |.|.|||.|.|   .| .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-------IVGYR---------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG

Kinase TTN.AA MLCK 6904-7158 61 1.1e-230 615.55 In-house 1-257 (257) Show / Hide
Range on Protein: 6904-7158
Range on HMM: 1-257/257
Sequence Identity: 61% (158 aa)

YQILEELGRGSYGIVYRAIEKKTQKTWAAKFMRC-FGKERDLVRREIEVMKKLHHRRLLNLHEVFETNEEIIMILEFLSGGELFDRLVDENHILTEPEVI
|||.|||||| .|||.|.|||.|.|||||||..|  .|....|..|||.|..|||..|...|. |||..|..||.|..||||||.| |||.. ||| |||
YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHLTEREVI

FYMKQTCEGVKHMHERHLVHLDLKPENIMLCARNSDDIKIIDFGLTMELDPDKP-VKIMFGTPDFIAPEVVNHEPIGLPTDMWALGVIAYLMLSGISPFE
.||.|.||||.|||... |||||||||||...|.|..|||||||| ...|||.. ||.|||||.|.||||||..|.|..||||..|||.|..|||.|||.
HYMRQICEGVHHMHWQNIVHLDLKPENIMCQTRTSHQIKIIDFGLARKYDPDEKKVKVMFGTPEFVAPEVVNYDPVGFQTDMWSVGVICYMLLSGLSPFM

GETDRETLKNVATGEWDFDEEAFADISDEGLDWIERILIKGKEGRMTIQEALDHPWL
|..||||..||  .|||||.|.| |||||..|.|.|.|.| || |||..|.|.||||
GDNDRETMNNVTSCEWDFDDECFDDISDEAKDFISRLLVKDKEKRMTAHECLQHPWL

Kinase TTN.AA DAPK 6906-7158 44 2.4e-130 361.27 In-house 1-264 (264) Show / Hide
Range on Protein: 6906-7158
Range on HMM: 1-264/264
Sequence Identity: 44% (117 aa)

ILEELGRGSYGIVYRAIEKKTQKTWAAKFMRCFGKERD-------LVRREIEVMKKLH-HRRLLNLHEVFETNEEIIMILEFLSGGELFDRLVD-ENHIL
. ||||||   .| ....|.| |  ||||..   . ..          .|| . ...  | .. |||||.||  ..|.|||  ||||||| ..      |
MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDREECL

TEPEVIFYMKQTCEGVKHMHERHLVHLDLKPENIMLCARNSDD--IKIIDFGLTMELDPDKPVKIMFGTPDFIAPEVVNHEPIGLPTDMWALGVIAYLML
.| ...  |||  |||...| |. .||||||.||||  ||. .  ||||||||  ....   .. ..|||...|||.|| ||..| ||||. |||.| ||
CEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFGLSRKICNGEEFRDIMGTPEYVAPEIVNYEPLSLATDMWSIGVITYIML

SGISPFEGETDRETLKNVATGEWDFDEEAFADISDEGLDWIERILIKGKEGRMTIQEALDHPWL
|||||| |.|  ||. |.     ||.|| |   | .  | | | | |  | |||..|.|.|||.
SGISPFLGDTKQETFLNISQVNYDFSEEYFSCTSEHAKDFIRRLLVKDPEKRMTAEECLQHPWI

Kinase TTN.AA CAMK 6909-7158 26 1.4e-115 374.04 In-house 1-425 (425) Show / Hide
Range on Protein: 6909-7158
Range on HMM: 1-425/425
Sequence Identity: 26% (113 aa)

ELGRGSYGIVYRAIEKKTQ------------KTWAAKFMRCF-----------------------------GKERDLVRREIEVMKK-------LHHRRL
.|||||.|.|...|.|.|.            . .|.|..                                .| |. ||||||.|||       |.|. .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LNLHEVFET-------------------NEEIIMIL---EFLSGGEL----FDRLVDENH--------------ILTEPEVIFYMKQTCEGVKHMHERHL
..|.||.|.                   .....|..   |. |||||    ||..|.  .               .|| |. .|..| |..|...|... 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHLDLKPENIMLCARNSDD---------------IKIIDFGLTMELDP------------------------DKPVKIMFGTPDFIA-PEVVNH------
||.|||||||.|. .|.|.               |||||||.  ..||                        ... | ..||| ..| |||.|       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------EPIGLPTDMWALGVIAYLMLSGISPFEGE-------------TDRETLKNVATGEWDFDEEAFAD------------ISDE--------GLD
        ...| ..|||..||| | ||.| .||.|.             .|.|..... .|..||... | .            ||||          |
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

WIERILIKGKEGRMTIQEALDHPWL
 | ..| .  | ||||...|.|||.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase TTN.AA DAPK 6904-7158 46 8.70000000001e-114 329.59 In-house 1-264 (264) Show / Hide
Range on Protein: 6904-7158
Range on HMM: 1-264/264
Sequence Identity: 46% (122 aa)

YQILEELGRGSYGIVYRAIEKKTQKTWAAKFMRC-------FGKERDLVRREIEVMKKLH-HRRLLNLHEVFETNEEIIMILEFLSGGELFDRLVDENHI
|.. ||.| | . .| .  ||.| |  |||| .         |  |. . ||. . ...  |     ||.|.|.  ....|||  ||||||| | .. . 
YDMGEEIGSGQFAVVKKCREKSTGKEYAAKFIKKRRYTASRRGVSREDIEREVSILREIRGHPNIITLHDVYENKTDVVLILELVSGGELFDFLCEKEC-

LTEPEVIFYMKQTCEGVKHMHERHLVHLDLKPENIMLCARNSDD--IKIIDFGLTMELDPDKPVKIMFGTPDFIAPEVVNHEPIGLPTDMWALGVIAYLM
|.| |   . ||  .||.||| .| .|.|||||||||  ||     ||||||||  . .| . .| .|||| |.|||.|| || || ||||. ||| | .
LNEEEATQFIKQILDGVHHMHSKHICHFDLKPENIMLLDRNVPNPRIKIIDFGLAHRIEPGNEFKNIFGTPEFVAPEIVNYEPLGLETDMWSIGVITYIL

LSGISPFEGETDRETLKNVATGEWDFDEEAFADISDEGLDWIERILIKGKEGRMTIQEALDHPWL
||| ||| |.|  ||| |.   . .|||| | . |    | | | |.|  . ||||||.| ||| 
LSGASPFLGDTKQETLANITAVNYHFDEEYFKNTSEHAKDFIRRLLVKDPKKRMTIQECLQHPWI

Kinase TTN.AA Trio 6904-7158 38 3.2e-113 291.58 In-house 1-258 (258) Show / Hide
Range on Protein: 6904-7158
Range on HMM: 1-258/258
Sequence Identity: 38% (100 aa)

YQILEELGRGSYGIVYRAIEKKTQKTWAAKFMRCFGKERDLVRREIEVMKKLHHRRLLNLHEVFETNEEIIMILEFLSGGELFDRLVDENHILTEPEVIF
| ..||.|||  ..| | ..| |..| ||||     . .. |..| |... |.| ... ||. .||    | |||  ..||| ..|..    ..| ||..
YTFQEEIGRGRFSVVRRCWHKATGRTCAAKFIPYRMMDKEQVYHEYEMLQHLQHPCVCSLHDTYETPRHYILILELCDDGELLCCLMRWGS-YCESEVKT

YMKQTCEGVKHMHERHLVHLDLKPENIMLCARNS--DDIKIIDFGLTMELDPD--KPVKIMFGTPDFIAPEVVNHEPIGLPTDMWALGVIAYLMLSGISP
|| |  |.|   |  |  |||.||||.|. ..|    .|||.|||  ..|.|   .|     |.| | |||... .|... || |. ||..|.|||||||
YMWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSIGVLTYVMLSGISP

FEGETDRETLKNVATGEWDFDEEAFADISDEGLDWIERILIKGKEGRMTIQEALDHPWL
| .| ||||..|.  |  .| |. |. .| .  . |  .|     .| . .|.| |||.
FYDESDRETCMNICRGDFSFPECYFCHVSQNAKHFICKVLQEDPWKRPCASECLQHPWF

Kinase TTN.AA DRAK 6908-7158 41 2.3e-93 290.49 In-house 3-259 (259) Show / Hide
Range on Protein: 6908-7158
Range on HMM: 3-259/259
Sequence Identity: 41% (107 aa)

EELGRGSYGIVYRAIEKKTQKTWAAKFMRCFGKERDL---VRREIEV-MKKLHHRRLLNLHEVFETNEEIIMILEFLSGGELFD-RLVDENHILTEPEVI
 |.||| . .| ..|.| | . .|||||.   . .|    . .|| | |      .. |||||.||  |.|..||. .|||.|.  . |.   ..| .|.
KERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDCRMEILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFCEKDVQ

FYMKQTCEGVKHMHERHLVHLDLKPENIMLCARNS-DDIKIIDFGLTMELDPDKPVKIMFGTPDFIAPEVVNHEPIGLPTDMWALGVIAYLMLSGISPFE
  |.|  |||. .|.|  ||||||| ||.|    . |||||.|||.   .     |  . ||||..|||. | .|| . ||||  ||..|.||..|||| 
RCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEEVREIMGTPDYVAPEILNYDPITMATDMWSIGVLTYVMLTHISPFV

GETDRETLKNVATGEWDFDEEAFADISDEGLDWIERILIKGKEGRMTIQEALDHPWL
|..  ||  |.     |. || |  .|..  | | ... .  | ||| .| ||||||
GDDKQETFLNISQCNLDYSEEMFSCHSPVAIDFIQSLCVIKPEDRMTAEECLDHPWL

Kinase TTN.AA S_TKc 6904-7158 32 3.2e-89 303.64 SMART 1-231 (231) Show / Hide
Range on Protein: 6904-7158
Range on HMM: 1-231/231
Sequence Identity: 32% (89 aa)

YQILEELGRGSYGIVYRAIEKKTQKTWAAKFMRCFGKERDLVRREIEVMKKLHHRRLLNLHEVFETNEEIIMILEFLSG--GELFDRLVDENHI-----L
|.||...|.|..| ||....|||..  | | ..      . .||||...|| ||  . .|..||.. ... |..|...|  |.|||.... ..      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TEPEVIFYMKQTCEGVKHMHERHLVHLDLKPENIMLCARNSDDIKIIDFGLTMELDPDKPVKIMFGTPDFIAPEVVNHEPIGL-PTDMWALGVIAYLMLS
.| .. |||.|.|......|... .| |||||||.|.      |||.||||  .|      . . |||...||||.   . |  . |.|..|.| | ||.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GISPFEGETDRETLKNVATGEWDFDEEAFADISDEGLDWIERILIKGKEGRMTIQEALD-------HPWL
|  ||.  .. ...|..               |.|..| |...| |  | |.|. |||        |||.
GYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase TTN.AA Pkinase 6904-7158 30 1.3e-81 282.19 Pfam 1-293 (293) Show / Hide
Range on Protein: 6904-7158
Range on HMM: 1-293/293
Sequence Identity: 30% (90 aa)

YQILEELGRGSYGIVYRAIEKKTQKTWAAKFMRCFGKERDL---VRR--EIEVMKKLHHRRLLNLHEVFETNEEIIMILEFLSGG----ELFDRLV-DEN
|.|.. .|.||.| ||....|.|.|..| | ..  ... .     ||  ||..||.|.|   . |...||.. .| |..|.. ||    .|||..  ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

HIL--TEPEVIFYMKQTCEGVKHMHERHLVHLDLKPENIMLCARNSDD---IKIIDFGLTME--LDPDKPVKIMFGTPDFIAPEVVN-HEPIGLPTDMWA
  .  .| |..|||.|...|....|..  .| |||||||..  .| .    .||.||||     . ..   .   |||...||||.. ....| . |||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVIAYLMLSGISPFEGE------TDRETLKNVATGEWDFDEEAFADIS-----------------DEGLDWIERILIKGKEGRMTIQEALDHPWL
.|.| | ||.|  || |.      .... ....  ....||..   .||                 .|..| |...| |  . | |....| |||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase TTN.AA CAMK1 6904-7158 34 1.4e-81 236.95 In-house 1-276 (276) Show / Hide
Range on Protein: 6904-7158
Range on HMM: 1-276/276
Sequence Identity: 34% (95 aa)

YQILEELGRGSYGIVYRAIEKKT---QKTWAAKFMR----CFGKER---DLVRREIEVMKK---LHHRRLLNLHEVFETNEEIIMILEFLSGGELFDRLV
|.. .|.|||. ..||....|.|   .| .| | .       .|..   .....|||.|||   ..|    ...|..|..... ...| ..||||||| |
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

DENHILTEPEVIFYMKQTCEGVKHMHERHLVHLDLKPENIMLCARNSDD--IK--IIDFGLTMELDPDK-PVKIMFGTPDFIAPEVVNH---EPIGLPTD
.  .  || .    ||| .. |..||..  || ||||||. |.. ...|  ||  |.||||   .|.|    | ..|||...||||..    .| . . |
EKGNY-TEKDARHIMKQILSAVEYMHSKGIVHRDLKPENL-LYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACD

MWALGVIAYLMLSGISPFEGET-DRETLKNVATGEWDFDEEAFADISDE-GLDWIERILIKGKEGRMTIQEALDHPWL
||  ||| | .| | .|| .|. | | .. .  .|..|..  . .|||.   | |   | .  . | |....|.|||.
MWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI

Kinase TTN.AA Ciliate-E2a 6904-7158 35 6.2e-75 220.01 In-house 1-275 (275) Show / Hide
Range on Protein: 6904-7158
Range on HMM: 1-275/275
Sequence Identity: 35% (97 aa)

YQILEELGRGSYGIVYRAIEKKTQKTWAAK----FMRCFGKERDLVRREIEVMKKLHHRRLLNLHEVFETNEEIIMILEFLSGGELFDRLVDENHILTE-
| .. ..| |..| || |  |.| |  |.|    .|.  .|..  . .||  |..| |  .. |.||.|..  . ...|...||||.|...    . .| 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

PEVIFYMKQTC-EGVKHMHERHLVHLDLKPENIML--CARNS---DDIKIIDFGLTMELDPDKP--VKIMFGTPDFIAPEVVNHEPI------GLPTDMW
 |.  .|.|   .|. .|| |. .| |||||||..  |  ||    |||||||||    |.|..  .. . ||| ..|||| | . .      .   |||
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMW

ALGVIAYLMLSGISPFEGETDRETLKNVATGEWDFDEEA-FADISDEGLDWIERILIKGKEGRMTIQEALDHPWL
 .||| |..|.| .||.|.| .|.|...   . ||.    . ..|.|  | . . | |  . | |.|.||.||| 
SCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF

Kinase TTN.AA CAMK-Unique 6904-7158 22 1.4e-71 235.5 In-house 1-363 (363) Show / Hide
Range on Protein: 6904-7158
Range on HMM: 1-363/363
Sequence Identity: 22% (81 aa)

YQILEELGRGSYGIVYRAIEKKTQKTWAAKFMRC--FGKERDLV-------------------RREIEVMKKLHHRRLLNLHEV----FETNE-------
|  .. .| |..|.||... ..| | || |  .    | .. ..                   .||....|.. | ... | ..    |.. .       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------EIIMILEFLSGGELFDRLVDE-------------------NHILTE--PEVIFYMKQTCEGVKHMHERHLVHLDLKPENIMLCAR-------
        .. ...|.. ||.||| ...                    . ...|   ...|.| .. . |..||.   || |||.||||.| .       
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-------NSDDIKIIDFGLTMELD-PDKP--VKIMFGTPDFIAP--------------EVVNHEPIGLPT----DMWALGVIAYLMLSGISPFEGETDR-
       .  .||..||||  ...   ..   ..| |||...||              ||.|  ... .     | |.||||.|.||.|..||..|..  
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------ETLKNVATGEW-DFDEEAFAD---ISDEGLDWIERILIKGKEGRMTIQEALDHPWL
       |....   |.  .||.... .   ||.|. | ... .      | .. |.|.|.|.
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase TTN.AA Ciliate-E2 6904-7158 21 2.8e-68 233.17 In-house 1-365 (365) Show / Hide
Range on Protein: 6904-7158
Range on HMM: 1-365/365
Sequence Identity: 21% (83 aa)

YQILEELGRGSYGIVYRAIEKKTQKTWAAKFMRCFG----------------------KERDLVRREIEVMKKLH----------------HRRLLNLHE
| ... .|.|..|.||..  .|.||  | |. . .                       ..   . .|| .|....                |  .....|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VFE--TNEEIIMILEFLSGGELFDRLVDENHI----------LTEPEVIFYMKQTCE---------------GVKHMHERH-LVHLDLKPENIMLCARNS
.|.  ... | ...|...||.|||.. . ..           .|| |....||| ..               .....|...  .| |.|||||..     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

DDIKIIDFGLTMELDPD----------KPVKIMF-----------------------GTPDFIAPEVVNHEP---------IGLPTDMWALGVIAYLMLS
  ||||||||  ..|.|          |  .  .                       ||| . |||..| ..          .   |.|.|||| | ||.
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GISPFEGETDRETLKNVATGEWDFDEE--------------AFADISDEGLDWIER----ILIKGKEGRMT-IQEALDHPWL
|  ||        ...   ...||...               . ..|.|. | | .    .| |  | |.| ....|.|||.
GKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase TTN.AA Pkinase_Tyr 6904-7025 23 2.3e-14 49.3 Pfam 1-137 (270) Show / Hide
Range on Protein: 6904-7025
Range on HMM: 1-137/270
Sequence Identity: 23% (33 aa)

YQILEELGRGSYGIVYRAIEK----KTQKTWAAKFMRCFGKERD-----LVRREIEVMKKL-HHRRLLNLHEVFE-TNEE--IIMILEFLSGGELFDRLV
 .....||.|..| ||... |    .|. . | | ..    ...     . | |...||.| ||  ...|. |     |   |....|.  .| | | | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

DE---NHILTEPEVIFYMKQTCEGVKHMHERHLVHLDL
.    .. || .. . .  | ..|  . ......| ||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL

Kinase TTN.AA TyrKc 6904-7158 21 2.6e-13 -7.54 SMART 1-280 (280) Show / Hide
Range on Protein: 6904-7158
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

YQILEELGRGSYGIVYRAIEKKTQKTWAAKFMRCFGKERDLVRREIEVMKKL--HHRRLLNLHEVFETN-------EEIIMILEFLSGGELFDRLVDENH
 . ...||.| .|.||... |    . | | ..     |   .||...|.||  ||  ...|. |  .        | . ...|. ..| | |.| .  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

ILTEPEVIFYMKQTCEGVKHMHERHLVHLDLKPENIMLCARNSDDIKIIDFGLTMELDPD------KPVKIMFG--TPDF------IAPEVVNHEPIGLP
 |. .. . .. | ..|  . |.....| ||   |... ...   .|| ||||. ... |      | .. . .    ..       |||. |.      
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

TDMWALGVIAYLMLS-GISPFEG-----ETDRETLKNVATGEWDFDEEA-----FADISDEGLDWIERILIKGKEGRMTIQEALDHPWL
.| |. ||  . ... | .| .|      ...| ...| .|.     .      |   .||  . ...      | | | .|   |  .
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

I-set TTN.AA I-set 7232-7321 36 2.6e-26 91.78 Pfam 1-92 (92) Show / Hide
Range on Protein: 7232-7321
Range on HMM: 1-92/92
Sequence Identity: 36% (34 aa)

PKFIKPLENTMAIEGNAGRFECEVSALSEPLITWFRGKKELII-SIKYKMLYDD-HKYTLIVQDSEFDDIDEYTCKAVNSYGHATSSASLDV
|||.... .  . || . ||||.|.   .| ..||.. ..|   | ...| ||.   |||.... . ||  .|||.|.||.| |...|.| |
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IGc2 TTN.AA IGc2 7244-7311 22 6e-08 33.66 SMART 1-56 (56) Show / Hide
Range on Protein: 7244-7311
Range on HMM: 1-56/56
Sequence Identity: 22% (15 aa)

IEGNAGRFECEVSALSEPLITWFRGKKELIISIKYKMLYDDHKYTLIVQDSEFDDIDEYTCKAVNSYG
.||.. ...|....  .| |.|..   .  ..         .. || ... ...|  .|||.| |. |
HEGQSVTLTCPATGNPDPNIHWYK---GQPLP---------WNWTLTIKNVTPEDSGYYTCYARNPWG

IG TTN.AA IG 7238-7322 18 9.4e-08 33.01 SMART 1-58 (58) Show / Hide
Range on Protein: 7238-7322
Range on HMM: 1-58/58
Sequence Identity: 18% (17 aa)

LENTMAIEGNAGRFECEVSALSEPLITWFRGKKELIISIKYKMLYDDHKYTLIVQDSEFDDI---DEYTCKAVNSYGHATS--SASLDVQ
 . . . ||   ...| ||      |.|.                      |.. . ...|     .|.| |   .| ..|  .. | ||
PP-VTVKEGETVTLTC-VS-----QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

V-set TTN.AA V-set 7231-7321 13 2.130106 3.2 Pfam 1-128 (128) Show / Hide
Range on Protein: 7231-7321
Range on HMM: 1-128/128
Sequence Identity: 13% (17 aa)

APKFIK-PLE----NTMAIEGNAGRFECEVSALS----EP-LITWFR-GKK----ELII-------------------SIKYKMLYDDH--KYTLIVQDS
.      | .      .. ||   ...| .| ..     .  |.|.| ..     ..||                   . .. .  .    ...|  .. 
QSQVTQHPPRGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNL

EFDDIDEYTCKAVNS-YGHATSSASLDV
. .|   |.| . |. ..   ..  | |
QPSDSGTYYCAVWNCNEDYFGHGTRLTV

I-set TTN.AA I-set 7396-7460 29 4.6e-15 53.64 Pfam 26-92 (92) Show / Hide
Range on Protein: 7396-7460
Range on HMM: 26-92/92
Sequence Identity: 29% (20 aa)

GMPEPKVKWYHEDRPLKP-GAHYHFYEED-GVHTLEIDGTTEKDKGQYTAEISNQYGSIATKCRLDV
| |.|.| |.. ..||.| . .... ... | .||.|.. .  | |.||   .| .|.  ....| |
GDPPPQVSWFKDGQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IGc2 TTN.AA IGc2 7387-7450 27 0.006014 3.16 SMART 1-56 (56) Show / Hide
Range on Protein: 7387-7450
Range on HMM: 1-56/56
Sequence Identity: 27% (19 aa)

LSFQVAEI--P--GMPEPKVKWYHEDRPLKPGAHYHFYEEDGVHTLEIDGTTEKDKGQYTAEISNQYG
.. | ...  |  | |.| ..||. . ||            .  ||.|   |. | | || . .|  |
HEGQSVTLTCPATGNPDPNIHWYK-GQPLP-----------WNWTLTIKNVTPEDSGYYTCYARNPWG

IG TTN.AA IG 7366-7461 12 0.091492 6.28 SMART 1-58 (58) Show / Hide
Range on Protein: 7366-7461
Range on HMM: 1-58/58
Sequence Identity: 12% (13 aa)

KAPQLIRPLEDQ--ECGFSFIMPLSFQVAEIPGMPEPKVKWYHEDRPLKPGAHYHFYEEDGVHTLEIDGTTEKDK---GQYTAEISNQYGSIAT--KCRL
   .. .. |.   .| .|                   ..||                      |.| . .. |    | |. . .  .|..      .|
PP-VTVKEGETVTLTC-VS------------------QIWWY----------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTL

DVN
 | 
TVQ

I-set TTN.AA I-set 7474-7565 33 3.9e-30 104.78 Pfam 1-92 (92) Show / Hide
Range on Protein: 7474-7565
Range on HMM: 1-92/92
Sequence Identity: 33% (31 aa)

PHFDLHLRDIFIVEGSAARLDCKVTGVPEPNIRWFKDHKEIFD-GQHYSIEFGEDDETCSLIIQEAFLQDAGTYTCLASNLLGRISCDSYVRV
|.|. ...|. . ||..||..|.||| |.| . |||| ...   ...... . . | |..|.|....  |.|.||| |.| .|  .|.  . |
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKDGQPLRPDSDRHQMTYDG-DGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IGc2 TTN.AA IGc2 7486-7555 31 1.5e-14 55.57 SMART 1-56 (56) Show / Hide
Range on Protein: 7486-7555
Range on HMM: 1-56/56
Sequence Identity: 31% (22 aa)

VEGSAARLDCKVTGVPEPNIRWFKDHKEIFDGQHYSIEFGEDDETCSLIIQEAFLQDAGTYTCLASNLLG
 || ...| |..|| |.|||.|.|   .  .               .| |... . |.|.|||.|.|  |
HEGQSVTLTCPATGNPDPNIHWYK--GQPLP------------WNWTLTIKNVTPEDSGYYTCYARNPWG

IG TTN.AA IG 7480-7566 18 2.2e-11 45.07 SMART 1-58 (58) Show / Hide
Range on Protein: 7480-7566
Range on HMM: 1-58/58
Sequence Identity: 18% (17 aa)

LRDIFIVEGSAARLDCKVTGVPEPNIRWFKDHKEIFDGQHYSIEFGEDDETCSLIIQEAFLQDA---GTYTCLASNLLGRISC--DSYVRVE
 . .  .||. ..| | |.     .|.|.                        |.| .. ..|.   |||.| |.   | ...    ...|.
PP-VTVKEGETVTLTC-VS-----QIWWY------------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

V-set TTN.AA V-set 7481-7565 18 0.002947 13.06 Pfam 10-128 (128) Show / Hide
Range on Protein: 7481-7565
Range on HMM: 10-128/128
Sequence Identity: 18% (22 aa)

R----DIFIVEGSAARLDCKVT---GVPEPN--IRWFK-DHK---------------EIFDGQHYSIEFGEDDE--------TCSLIIQEAFLQDAGTYT
|     .. .||  ..| |...     .|.|  | |..                     |....|. .| .  .        ..|| |. . . | |||.
RGCPWWVTVQEGQSVTLPCHYSDDYTCWEHNFYIYWYRQQPPGQKPQWIISYYTHYYYNFGHGYYYPRFKGRVTFSGNPSKNDFSLTISNLQPSDSGTYY

CLASNL-LGRISCDSYVRV
| ..|   .       ..|
CAVWNCNEDYFGHGTRLTV