Trad

Species: Sea Urchin
Alias: Trad, SPU_019190, Spk082
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: CAMK
Family: Trio

Sequence

Name Sequence Type Origin Length Description Download
Trad.AA Protein None 697 None Fasta, JSON
Trad.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of Trad.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
I-set Trad.AA I-set 181-272 35 3.7e-19 67.51 Pfam 1-92 (92) Show / Hide
Range on Protein: 181-272
Range on HMM: 1-92/92
Sequence Identity: 35% (33 aa)

PAFTLPLINQSCHLGTTATLSCQVCGRPRPMITWRDPQGDIIAP-STRTNVWERDDGMVFLEIRASCKLDNGVYTCTASNDAGSTECKALLRI
| || .. .. .  | ||...||| | | | ..|    |  ..| | | .. ...||  .|.|.  .. | |.|||.|.| .|. ||.| | .
PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSWFKD-GQPLRPDSDRHQMTYDGDGTYTLTISNVQPDDEGKYTCVATNSFGEAECTAELTV

IGc2 Trad.AA IGc2 193-262 30 2.8e-10 41.39 SMART 1-56 (56) Show / Hide
Range on Protein: 193-262
Range on HMM: 1-56/56
Sequence Identity: 30% (21 aa)

HLGTTATLSCQVCGRPRPMITWRDPQGDIIAPSTRTNVWERDDGMVFLEIRASCKLDNGVYTCTASNDAG
| |...|| | . |.| | |.|.   |  ..            .  .|.|.   . | |.|||.|.| .|
HEGQSVTLTCPATGNPDPNIHWYK--GQPLP------------WNWTLTIKNVTPEDSGYYTCYARNPWG

IG Trad.AA IG 187-273 18 3.4e-07 31.16 SMART 1-58 (58) Show / Hide
Range on Protein: 187-273
Range on HMM: 1-58/58
Sequence Identity: 18% (17 aa)

LINQSCHLGTTATLSCQVCGRPRPMITWRDPQGDIIAPSTRTNVWERDDGMVFLEIRASCKLDN---GVYTCTASNDAGSTEC--KALLRII
   ..  .| |.||.| |       |.|.                        |.|    . |    |.|.|.|.  .|....   . |.. 
PP-VTVKEGETVTLTC-VS-----QIWWY------------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ

FN3 Trad.AA FN3 276-360 21 3e-12 47.96 SMART 1-69 (69) Show / Hide
Range on Protein: 276-360
Range on HMM: 1-69/69
Sequence Identity: 21% (21 aa)

PGPPSI---PILCERRPH------SVTLQWEPSHNTGNAESVTYNVEYAQITHNTLHWQTSCANIAHTTHKVDALSAG----ASYKFRITAQND--VGCS
||||.    . . .  ..      ||||.|.|             |.|                     ..|. |..|      |.||..| |.  .| .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-----------IVGYR--------------------YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG





Kinase Trad.AA Trio 394-650 53 2.4e-232 603.66 In-house 1-258 (258) Show / Hide
Range on Protein: 394-650
Range on HMM: 1-258/258
Sequence Identity: 53% (139 aa)

FNITREIGRGRFSSTHACTRSQQQRTLAAKFISKRLMDLEQVQHEASMMQPLQHPLICSLHATYETHGQYILVLDLIPDGRILEYLVSLSQVTERQVIGF
.....||||||||....|......||.|||||..|.||.|||.||..|.|.||||..||||.||||...|||.|.|..||..|..|.......|..|...
YTFQEEIGRGRFSVVRRCWHKATGRTCAAKFIPYRMMDKEQVYHEYEMLQHLQHPCVCSLHDTYETPRHYILILELCDDGELLCCLMRWGSYCESEVKTY

IRQLVQAVNYLHSNGIIHLDIKPENVMMEKALG-RAQIKLIDFGDAMDLWSSPPPFYHELNANPEFCSPELLGGNEIDYGTDVWSIGALSYVMLSGISPF
..|...||.|||...|.||||||||.||..... |.|||..|||||..||.......|....||||..||...||...||||.||||.|.||||||||||
MWQMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSIGVLTYVMLSGISPF

LDESLEETNMNIIRVDYSFPEEYFKNVSQNAKHFITGLLHADSSERKTTSECLMNHWF
.|||..||.|||.|.|.||||.||..|||||||||...|..|...|...||||...||
YDESDRETCMNICRGDFSFPECYFCHVSQNAKHFICKVLQEDPWKRPCASECLQHPWF

Kinase Trad.AA MLCK 394-650 35 1e-98 260.59 In-house 1-257 (257) Show / Hide
Range on Protein: 394-650
Range on HMM: 1-257/257
Sequence Identity: 35% (92 aa)

FNITREIGRGRFSSTHACTRSQQQRTLAAKFISK-RLMDLEQVQHEASMMQPLQHPLICSLHATYETHGQYILVLDLIPDGRILEYLV-SLSQVTERQVI
..|. |.|||.|. .| |.  . ..|.|||||   .  | | |..| ..|  |.|| .  .|. .||  . ......|  | ..|. | .    |||.||
YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRKPKDKENVKNEIEIMNQLHHPNLIQCHDAFETKNEMVMIMEYISGGELFERIVDEDFHLTEREVI

GFIRQLVQAVNYLHSNGIIHLDIKPENVMMEKALGRAQIKLIDFGDAMDLWSSPPPFYHELNANPEFCSPELLGGNEIDYGTDVWSIGALSYVMLSGISP
 ..||.  .| ..|...|.|||.||||.|.  .    |||.|||| |. .    ..    . . |||..||      ....||.||.| ..|..|||.||
HYMRQICEGVHHMHWQNIVHLDLKPENIMC-QTRTSHQIKIIDFGLARKYDPDEKK-VKVMFGTPEFVAPEVVNYDPVGFQTDMWSVGVICYMLLSGLSP

FLDESLEETNMNIIRVDYSFPEEYFKNVSQNAKHFITGLLHADSSERKTTSECLMNHWF
|. .. .||  |.  ... | .| |...|. || ||. ||  | ..| |..|||  .|.
FMGDNDRETMNNVTSCEWDFDDECFDDISDEAKDFISRLLVKDKEKRMTAHECLQHPWL

Kinase Trad.AA CAMK 399-650 19 3.5e-90 290.72 In-house 1-425 (425) Show / Hide
Range on Protein: 399-650
Range on HMM: 1-425/425
Sequence Identity: 19% (83 aa)

EIGRGRFSSTHACTRSQQQ------------RTLAAKFISKR-----------------------------LMDLEQVQHEASMMQPLQ-------HPLI
..|||.|.  . |.. . .            .  |.|.|.|.                               |...|..| ..|. ||       || |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CSLHATYE------------THGQ--------YILVL---DLIPDG----RILEYLVSLSQ---------------VTERQVIGFIRQLVQAVNYLHSNG
..|. .||            |  .        ...|.   .... |    ....|.|. ..               .|||..  ..||...||.|.||..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHLDIKPENVMMEKA--------------LGRAQIKLIDFGDAMDLWSSP----------------------PPFYHELNANPEFCS-PELLGG-----
|.|.|.||||... .               . ...||.|||| |  . ..                        . ...    ||... ||.| |     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------NEIDYGTDVWSIGALSYVMLSGISPFLDE-------------SLEETNMNIIRVDYSFPEEYFKN------------VSQN--------AK
           ... .|.||.| . |.||.| .|| ..             ...|.  .|.. .|.||..||..            .|..        .|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

HFITGLLHADSSERKTTSECLMNHWF
..| ..|  | ..| | ..||   |.
DLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase Trad.AA S_TKc 394-650 25 2.2e-59 204.53 SMART 1-231 (231) Show / Hide
Range on Protein: 394-650
Range on HMM: 1-231/231
Sequence Identity: 25% (70 aa)

FNITREIGRGRFSSTHACTRSQQQRTLAAKFISKRLMDLEQVQHEASMMQPLQHPLICSLHATYETHGQYILVLDLIPD--GRILEYLVSLSQ------V
. | |.||.| |.. . |.    .|  | | |.      |... | ....  .|| |. |. .... . . .|.....   |  ..|...          
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TERQVIGFIRQLVQAVNYLHSNGIIHLDIKPENVMMEKALGRAQIKLIDFGDAMDLWSSPPPFYHELNANPEFCSPELLGGNEIDY-GTDVWSIGALSYV
.| ..  ...|...|..|.||.|||| |.||||... .     .||..||| |  |        . .   |....||.|     ..   |.||.| . | 
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLSGISPFLDESLEETNMNIIRVDYSFPEEYFKNVSQNAKHFITGLLHADSSERKTTSECLM-------NHWF
||.|  ||     ... ...|.             |. ||.|| ..|. | ..| |  |.|          ||
MLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase Trad.AA DRAK 397-650 33 9.6e-59 180.93 In-house 2-259 (259) Show / Hide
Range on Protein: 397-650
Range on HMM: 2-259/259
Sequence Identity: 33% (87 aa)

TREIGRGRFSSTHACTRSQQQRTLAAKFISKRLMDL---EQVQHE-ASMMQPLQHPLICSLHATYETHGQYILVLDLIPDGRILE--YLVSLSQVTERQV
 .| |||.|     | . .  .  ||||. || .     . . || | .|   . | .  ||. |||    |||| .   | | .   .     ..|..|
AKERGRGKFAVVRKCIHKNTGQHFAAKFMKKRRRGQDCRMEILHEIAVLMLCQDCPWVINLHEVYETRSEMILVLEYAAGGEIFQYCVADKEECFCEKDV

IGFIRQLVQAVNYLHSNGIIHLDIKPENVMMEKALGRAQIKLIDFGDAMDLWSSPPPFYHELNANPEFCSPELLGGNEIDYGTDVWSIGALSYVMLSGIS
.  .||  ..| |||.. |.||| || |...        ||..||| .  .  .      |.   |..  || |  . |   ||.|||| | ||||..||
QRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEE--VREIMGTPDYVAPEILNYDPITMATDMWSIGVLTYVMLTHIS

PFLDESLEETNMNIIRVDYSFPEEYFKNVSQNAKHFITGLLHADSSERKTTSECLMNHWF
||. .   || .||  .  ...|| |  .|. |  ||  |.  .  .| |  |||   | 
PFVGDDKQETFLNISQCNLDYSEEMFSCHSPVAIDFIQSLCVIKPEDRMTAEECLDHPWL

Kinase Trad.AA Pkinase 394-650 24 1.4e-56 199.12 Pfam 1-293 (293) Show / Hide
Range on Protein: 394-650
Range on HMM: 1-293/293
Sequence Identity: 24% (73 aa)

FNITREIGRGRFSSTHACTRSQQQRTLAAKFISKRLMDLEQVQH-----EASMMQPLQHPLICSLHATYETHGQYILVLDLIPDG----RILEYLV--SL
. | | ||.| |..   |..   ... | | |.||  . .. |.     |...|. |.|| |. |. ..|... . .|... . |       .|.   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SQV--TERQVIGFIRQLVQAVNYLHSNGIIHLDIKPENVMMEKALGR-AQIKLIDFGDA--MDLWSSPPPFYHELNANPEFCSPELLG-GNEIDYGTDVW
  .  .|.... ...|......|.||.|||| |.||||... .     | .|..||| |  .|    . . .. .   |....||..  |.....  |.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SIGALSYVMLSGISPFLDE------SLEETNMNIIRVDYSFPEEYFKNVS-----------------QNAKHFITGLLHADSSERKTTSECLMNH-WF
|.| . | ||.|  || ..      .  .   .| . ...|....  ..|                 ...|.||...|. | ..| |  |....| ||
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-AEQILQHPWF

Kinase Trad.AA Ciliate-E2 394-650 20 2.2e-54 185.11 In-house 1-365 (365) Show / Hide
Range on Protein: 394-650
Range on HMM: 1-365/365
Sequence Identity: 20% (79 aa)

FNITREIGRGRFSSTHACTRSQQQRTLAAKFISKRL----------------------MDLEQVQHEASMMQ----------------PLQHPLICSLHA
... . ||.| |.|   |.. ..|.  | |.|  ..                       ..||.  | ..|.                 |.|| |. .. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

TYE--THGQYILVLDLIPDGRILEYLVSL-----------SQVTERQVIGFIRQLVQ---------------AVNYLHSNG-IIHLDIKPENVMMEKALG
...  .   . ||....  |  ..|. .             . ||.... ...|..|               |..||||.. ||| ||||||...     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

RAQIKLIDFGDAMDLWSSPPPFYHELNA-------------------------------NPEFCSPELLGGNE---------IDYGTDVWSIGALSYVML
   ||.|||| . ..  .    .| ..                                .|.. .|| |.| .          ||  |.||.| . | ||
---IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML

SGISPFLDESLEETNMNIIRV-DYSFPEE--------------YFKNVSQNAKHFITG----LLHADSSERKT-TSECLMNHWF
.|  ||         ...|   ...||..               .|..||..|..|      .|  | ..| |  ...| ..||
FGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase Trad.AA CAMK-Unique 438-650 19 9.2e-49 158.99 In-house 66-363 (363) Show / Hide
Range on Protein: 438-650
Range on HMM: 66-363/363
Sequence Identity: 19% (57 aa)

EASMMQPLQHPLICSLHAT----YETHG---------------QYILVLDLIPDGRILEYLVS--------------------LSQVTE--RQVIGFIRQ
|.. .. . || |  |  .    ...                  . .|......|  ......                      . .|  ....  ...
EHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQC

LVQAVNYLHSNGIIHLDIKPENVMMEKALG-------------RAQIKLIDFGDAMDLWSSPPP-FYHELNANPEFCSP--------------ELLGGNE
|..||.|.||..|.| |.|.||.|  . .              .  |||.||| . .. ..  .   ..    |....|              |....  
LLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQC

IDYGT----DVWSIGALSYVMLSGISPFLDESLE--------ETNMNIIRVDY-SFPEEYFKN---VSQNAKHFITGLLHADSSERKTTSECLMNHWF
.|.      | ||.|.. | ||.|..||  |. .        |.  .|   || .|.....     .||.|| |.....  | . | . .| | . |.
YDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase Trad.AA Ciliate-E2-Unclassified 394-650 20 6.8e-44 150.14 In-house 1-352 (352) Show / Hide
Range on Protein: 394-650
Range on HMM: 1-352/352
Sequence Identity: 20% (74 aa)

FNITREIGRGRFSSTHACTRSQQQRTLAAKFISKRLMDLEQVQHEAS---------------------------MMQPLQHPLICSLHATYETHGQYILV
..| . ||.| |.. . | ...|.  ..|. . |  ..  | | . .                            .. ..||.|  .. . ..    ..|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LDLIPDGRILEYLVSLSQ-----------------VTERQVI-----GFIRQLVQAVNYLHSNG-IIHLDIKPENVMMEKALGRAQIKLIDFGDAMDLWS
......|  ..|. . ..                 .||.|..      ...|..|. .|||... ||| ||||||... .  .. .||.|||| .. . .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

S--------------PPPFYHELNANPEFC----SPELLGGNEID----YGTDVWSIGALSYVMLSGISPFLDESLEE---------------TNMNII-
.              ..  ..    .|..     .||.|.|.. |    |  |.|| | . | || |  || |.. |.                  ..| 
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

RVDYSFPEEYF----KNVSQNAKHFIT----GLLHADSSERKTTSECLMNHWF
  ...||.. .    |..|..||.||.     .|  . ..| | .. |  .||
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase Trad.AA DAPK 396-536 32 7.7e-41 110.0 In-house 1-152 (264) Show / Hide
Range on Protein: 396-536
Range on HMM: 1-152/264
Sequence Identity: 32% (49 aa)

ITREIGRGRFSSTHACTRSQQQRTLAAKFISKRLMDLE-------QVQHEASMMQPLQ-HPLICSLHATYETHGQYILVLDLIPDGRILEYLVS--LSQV
. .|.|||.|.    |.     .  ||||| || .             || .  . .. || . .||. |||    ||.| .   | .  |..      .
MGEELGRGQFAVVRKCRHKSTGKHYAAKFIKKRRRGQSRRGVCREEIEHEIAILEECRGHPNVINLHEVYETRTDVILILEYVSGGELFDYCCEDREECL

TERQVIGFIRQLVQAVNYLHSNGIIHLDIKPENVMMEK-ALGRAQIKLIDFG
.| ... |..|  ..|.||||. | |||.||.|.|          ||.||||
CEEDATRFMKQILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFG

Kinase Trad.AA DAPK 556-650 47 6.6e-36 96.16 In-house 170-264 (264) Show / Hide
Range on Protein: 556-650
Range on HMM: 170-264/264
Sequence Identity: 47% (45 aa)

PEFCSPELLGGNEIDYGTDVWSIGALSYVMLSGISPFLDESLEETNMNIIRVDYSFPEEYFKNVSQNAKHFITGLLHADSSERKTTSECLMNHWF
||.  || .    .   || |||| . |.||||||||| .   ||  || .| |.|.||||...|. || ||  ||  |   | |  |||   | 
PEYVAPEIVNYEPLSLATDMWSIGVITYIMLSGISPFLGDTKQETFLNISQVNYDFSEEYFSCTSEHAKDFIRRLLVKDPEKRMTAEECLQHPWI

Kinase Trad.AA DAPK 394-536 32 2.4e-31 87.57 In-house 1-152 (264) Show / Hide
Range on Protein: 394-536
Range on HMM: 1-152/264
Sequence Identity: 32% (49 aa)

FNITREIGRGRFSSTHACTRSQQQRTLAAKFISKRLMDL-------EQVQHEASMMQPLQ-HPLICSLHATYETHGQYILVLDLIPDGRILEYLVSLSQV
. .  ||| | |.    |.        ||||| || .         | .  | |  . .. || | .||. ||.    .|.| |.  |    .|     .
YDMGEEIGSGQFAVVKKCREKSTGKEYAAKFIKKRRYTASRRGVSREDIEREVSILREIRGHPNIITLHDVYENKTDVVLILELVSGGELFDFLCEKECL

TERQVIGFIRQLVQAVNYLHSNGIIHLDIKPENVMMEKALGRAQ--IKLIDFG
.|     || |  ..|...||  | |.|.||||.|  .  . ..  ||.||||
NEEEATQFIKQILDGVHHMHSKHICHFDLKPENIML-LDRNVPNPRIKIIDFG

Kinase Trad.AA DAPK 573-650 52 3.2e-30 84.3 In-house 187-264 (264) Show / Hide
Range on Protein: 573-650
Range on HMM: 187-264/264
Sequence Identity: 52% (41 aa)

TDVWSIGALSYVMLSGISPFLDESLEETNMNIIRVDYSFPEEYFKNVSQNAKHFITGLLHADSSERKTTSECLMNHWF
|| ||||   |..||| |||| .  .||  || .| | | |||||| |. || ||  ||  |   | |  |||   | 
TDMWSIGVITYILLSGASPFLGDTKQETLANITAVNYHFDEEYFKNTSEHAKDFIRRLLVKDPKKRMTIQECLQHPWI

Kinase Trad.AA CAMK1 394-536 30 2.7e-29 82.27 In-house 1-158 (276) Show / Hide
Range on Protein: 394-536
Range on HMM: 1-158/276
Sequence Identity: 30% (48 aa)

FNITREIGRGRFSSTHACTRSQQ---QRTLAAKFIS-KRLMDL------EQVQHEASMMQ---PLQHPLICSLHATYETHGQYILVLDLIPDGRILEYLV
.... ||||| ||  . ||. .    ..  | | |. |. |.       |... | ..|.    ..|| | ...  ||.   . ||..|.  | ...  |
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

SLSQVTERQVIGFIRQLVQAVNYLHSNGIIHLDIKPENVMMEKALGRAQIK--LIDFG
   . ||..    ..|...||.|.||.|| | |.||||   .     ..||  ..|||
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFG

Kinase Trad.AA CAMK1 556-650 35 1.9e-23 65.0 In-house 177-276 (276) Show / Hide
Range on Protein: 556-650
Range on HMM: 177-276/276
Sequence Identity: 35% (35 aa)

PEFCSPELLGG---NEIDYGTDVWSIGALSYVMLSGISPFLDES-LEETNMNIIRVDYSFPEEYFKNVSQN-AKHFITGLLHADSSERKTTSECLMNHWF
|... || | .      |.  |.||||  .|..| | .|| ||.  .|    |.. .| ||. .. |.|   ||.||...|  | ..| | ..||   |.
PGYVAPEVLECKKDKPYDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI





Kinase Trad.AA TyrKc 394-650 18 8.8e-09 -80.63 SMART 1-280 (280) Show / Hide
Range on Protein: 394-650
Range on HMM: 1-280/280
Sequence Identity: 18% (54 aa)

FNITREIGRGRFSSTHACTRSQQQRTLAAKFISKRLMDLEQVQHEASMMQPL--QHPLICSLHATYETH-------GQYILVLDLIPDGRILEYLVSLSQ
    ...|.| |   . .| .   .. | | . .    .|   .||..|  |  .|| |  |..   ..       ... .|. . | |  ..|| .   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-VTERQVIGFIRQLVQAVNYLHSNGIIHLDIKPENVMMEKALGRAQIKLIDFGDAMDLWSS---PPPFYHELNA-----NPEF------CSPELLGGNEI
 .. .. . |  |  .  .||||...|| |.   |..  . .   ..|  ||| . |. .         ..        .  .      ..|| .  .. 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DYGTDVWSIGALSYVMLS-GISPFLD-----ESLEETNMNIIRVDYSFPEEY-----FKNVSQNAKHFITGLLHADSSERKTTSECLMNHWF
   .|||| | . . ... | .|  .      | .|   .. . ..  . ..     |   ..     ..   |.| ..| | ||.   . |
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase Trad.AA Pkinase_Tyr 394-511 20 1.3e-05 19.65 Pfam 1-134 (270) Show / Hide
Range on Protein: 394-511
Range on HMM: 1-134/270
Sequence Identity: 20% (28 aa)

FNITREIGRGRFSSTHACTRS----QQQRTLAAKFI--SKRLMD--LEQVQHEASMMQPL-QHPLICSLHATYE-THGQ--YILVLDLIPDGRILEYLVS
  . ...|.| | . . .|      ... . | | .  .    .  .|   .||..|  | .|| | .|..      ..  ...|. . | |  |.|| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----LSQVTERQVIGFIRQLVQAVNYLHSNGIIH
      ..|  . ... .|  .. .||.|...||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIH