Gene NEK6 (Sea Urchin)

NEK6

Species: Sea Urchin
Alias: NEK6, Spk170, SPU_028348
External Links: Sea Urchin Project Link ,
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK6

Sequence

Name Sequence Type Origin Length Description Download
NEK6.AA Protein None 338 None Fasta, JSON
NEK6.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of NEK6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NEK6.AA NEK6 25-276 88 1.5e-214 712.99 In-house 1-252 (252) Show / Hide 
Range on Protein: 25-276
Range on HMM: 1-252/252
Sequence Identity: 88% (223 aa)

FAIEKRIGKGQFSEVYRARCLINDRVTALKKVQIFEMMDAKARNDCIKEIDLLKSLDHDHVIKYLASFIENNELNIVLELADAGDLSRMIKHFKKQKRLI
|.|||.||||||||||||.||..|...||||||||||||||||.||||||||||.|.|..||||.||||||||||||||||||||.||||||||||||||
FQIEKKIGKGQFSEVYRAQCLWDDKHVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPNVIKYYASFIENNELNIVLELADAGDMSRMIKHFKKQKRLI

PERTIWKYFVQLCSALEHMHQKRVMHRDIKPANVFITADGKVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHETGYNFKSDIWSLGCLLYEMAALQ
||||||||||||||||||||.|||||||||||||||||.|.||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||
PERTIWKYFVQLCSALEHMHSKRVMHRDIKPANVFITANGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQ

SPFYGDKMNLYALCKKIDKCDYPPLPADHYTEELRNLVAMCIHPDPNLRPDV
|||||||||||.|||||..|||||||||||.|.||.||.|||||||..|||.
SPFYGDKMNLYSLCKKIEQCDYPPLPADHYSEQLRQLVCMCIHPDPEWRPDI
Kinase NEK6.AA NEK 25-285 37 2.8e-142 478.98 In-house 1-286 (286) Show / Hide 
Range on Protein: 25-285
Range on HMM: 1-286/286
Sequence Identity: 37% (109 aa)

FAIEKRIGKGQFSEVYRARCLINDRV-----TALKKVQIFEMMDAKARNDCI-KEIDLLKSLDHDHVIKYLASFIENN--ELNIVLELAD-AGDLSRM--
. | | ||.|.|..||..|. .. ..      ..||.. ...|. | . ... .|. .||.|.|....||  ||||..   |.|| | ..  |||...  
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN-MGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIK

-IKHFKKQKRLIPERTIWKYFVQLCSALEHMHQK-----RVMHRDIKPANVFITADGK----VKLGDLGLGRFFSSKTTAAHS-LVGTPYYMSPERIHET
 ||. |... ...|..||..|.|.|.|| .||..     ...||||||.|.|.|....    ||.||.|. . ....|..|.. .|||||||||| ... 
SIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNK

GYNFKSDIWSLGCLLYEMAALQS--PFYG-DKMNLYALCKKIDKC-DYPPLPADH-YTEELRNLVAMCIHPDPNLRPDVSYVLEVAKR
.||.|||||||||.||||..|..  ||.. | ||...|..|| |. .|||.|  . | ..|.||. .....|| .||... .||    
PYNNKSDIWSLGCVLYEMCTLKPKHPFEAWD-MNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase NEK6.AA S_TKc 25-289 29 9.8e-87 295.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-289
Range on HMM: 1-231/231
Sequence Identity: 29% (80 aa)

FAIEKRIGKGQFSEVYRARCLINDRVTALKKVQIFEMMDAKARNDCIKEIDLLKSLDHDHVIKYLASFIENNELNIVLELADA--GDLSRMIKHFKKQK-
. | . |||| |..||..|    .|. |.|..           .. ..||..||. .|....|.. .| . ..| .|.|..|   ||| ..||. .... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-RLIPERTIWKYFVQLCSALEHMHQKRVMHRDIKPANVFITADGKVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHETGYNF-KSDIWSLGCLLYE
 . .|| ....|. |.|.|||..|.....|||.||.|....    .|..| || |..       ....|||.||.|| .   ||.. |.|.||.||.|||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MAALQSPFYGDKMNLYALCKKIDKCDYPPLPADHYTEELRNLVAMCIHPDPNLRPDVSYVLE---VAKRMHMQ
|.. . ||.    ..... |||             ..|.....  | . ||. || .  .|.   ..| .   
MLCGYPPFP----QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NEK6.AA NEK8 62-280 40 2.2e-86 246.59 In-house 39-273 (278) Show / Hide 
Range on Protein: 62-280
Range on HMM: 39-273/278
Sequence Identity: 40% (97 aa)

MDAKARNDCIKEIDLLKSLDHDHVIKYLASFIENNELNIVLELADAGDLSRMIKHFKKQKRLIPER----------------TIWKYFVQLCSALEHMHQ
|. | |..   ||..|. |.|. .| |. .|.|.| | |..| || | | .|| |  . | . .||                .|  ||.| |||. ||||
MSEKERQMAQNEIQVLSMLQHPNIISYYDHFMEDNTLMIEMEYADGGTLYQMIQH-QQNKLFEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQ

KRVMHRDIKPANVFITAD-GKVKLGDLGLGRFFSSKTTAAHS--LVGTPYYMSPERIHETGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYALCKKID
. . |||.|..|.| | . . ||.|| |.    ..|. .. .  .||||||||||      ||.|||.|.||| ||||. |   | ..  || ||. || 
HNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDMWALGCVLYEMCCLKRAFEAS--NLPALVWKIM

KC-DYPPLPADHYTEELRNLVAMCIHPDPNLRPDVSYVL
 |  | |.. |||. |.| ||  |   ||  ||..| ..
QCRAYEPIS-DHYSNEMRMLVHNCLQQDPEQRPSASQIM
Kinase NEK6.AA NEK1 25-281 35 4e-72 245.91 In-house 1-272 (276) Show / Hide 
Range on Protein: 25-281
Range on HMM: 1-272/276
Sequence Identity: 35% (99 aa)

FAIEKRIGKGQFSEVYRARCLINDRVTALKKVQIFEMMDAKARNDCIKEIDLLKSLDHDHVIKYLASFIENNE--LNIVLELADAGDLSRMIKHFKKQKR
. . | ||.| |  .. ..     .. ..|  .. .| . | | .  .|  .|. ..|  ..||  ||.||    | || | .|.||| . |.  | .  
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQE-KEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGK

LIPERTIWKYFVQLCSALEHMHQKRVMHRDIKPANVFIT--ADG---------------KVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHETGYN
|..| .|  .|.|.| || |.| ....|||||. |.| |   .|               .||||| |  |  .. .  |   .||||| ||| .   .||
LFSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYN

FKSDIWSLGCLLYEMAALQSPFYGDKMNLYALCKKIDKCDYPPLPADHYTEELRNLVAMCIHPDPNLRPDVSYVLE
 ||||||||| |||  .|  || . ..   .|  || .  |||.|. || .||..||.     .| .|| |  .||
NKSDIWSLGCVLYELCTLKHPFEANNWK--NLVLKICQGTYPPIPP-HYSYELQSLVSQMFKRNPRHRPSVNQILE
Kinase NEK6.AA Pkinase 25-281 24 1.3e-70 245.74 Pfam 1-289 (293) Show / Hide 
Range on Protein: 25-281
Range on HMM: 1-289/293
Sequence Identity: 24% (72 aa)

FAIEKRIGKGQFSEVYRARCLINDRVTALKKVQIFEMMDAKARNDCI-KEIDLLKSLDHDHVIKYLASFIENNELNIVLELADAG----DLSRMIKHFKK
. |...||.| |..||...   . .. |.|..   .  . | ...    || ..|.|.|....... .| ..... .|.|... |    ||...|.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

QKRLI--PERTIWKYFVQLCSALEHMHQKRVMHRDIKPANVFITADGKV----KLGDLGLGRFF-SSKTTAAHSLVGTPYYMSPERIH-ETGYNFKSDIW
... .  .|... .|. |....||..|.....|||.||.|..|  .| .    |..| || ..|   . . .....|||.||.|| |   ..|  |.|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGCLLYEMAALQSPFYGD----KMNLYALCKKIDKCDYPPLPADHYT-------------------EELRNLVAMCIHPDPNLRPDVSYVLE
|.||.||||.  . ||.|.    ... ... ..| .....      ..                   ||.. ..  |...||. ||    .|.
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ
Kinase NEK6.AA STE 25-277 23 3.4e-68 232.88 In-house 1-349 (359) Show / Hide 
Range on Protein: 25-277
Range on HMM: 1-349/359
Sequence Identity: 23% (84 aa)

FAIEKRIGKGQFSEVYRARCL------INDRV---------TALKKVQIFEM--------------MDAKARNDCIKEIDLLKSLD--HDHVIKYLASFI
. . ..|||| | .||.|..        ...|          | |.. . .               .. . ... .|||...| ..  |....||. ...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EN-------NELNIVLELADAGDLSRMIK-HFKKQKRL---------IPERTIWKYFVQLCSA-LEHMHQKRVMHRDIKPANVFITADGKVKLGDLGLGR
 .       .||.|..|. |.| |. .||  ....|.|         .||  | .. .|.. . |.. |.....||||||||...     ||| | |.  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FFSSK--------------TTA--AHSLVGTPYYMSPERIHE------TGYNFKSDIWSLGCLLYEMAALQSPFYG-DKM-NLYALCKKIDKC-------
 ....              |..    ..|||| .|.||.|         ||..|.|||||||.. |||  . |.     | ....  ... ..       
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----DYPPLPAD------------------HYTEELRNLVAMCIHPDPNLRPDVS
    . |||| .                  ....|... .. |   ||| ||..|
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTAS
Kinase NEK6.AA CAMK 30-281 18 9.6e-63 200.71 In-house 1-421 (425) Show / Hide 
Range on Protein: 30-281
Range on HMM: 1-421/425
Sequence Identity: 18% (79 aa)

RIGKGQFSEVYRARCLINDRVT------------ALKKVQIFEMMD-------------------------AKARNDCIKEIDLLKS-------LDHDHV
 .|.|.|..|....   . . .            | | .    . |                         .| |    .||...|.       ||| ..
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKYLASFIE-------------------NNELNIVL---ELADAG----D-LSRMIKH-----------FKKQKRLIPERTIWKYFVQLCSALEHMHQKR
|| .  .                     .... .|.   |... |    | ... ..|           .  ... ..||   .|| |.|||....|.. 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

VMHRDIKPANVFITAD-----------------GKVKLGDLGLGRFFSSK-----------------------TTAAHSLVGTPYYMS-PERIH------
..|||.|| |. .. .                 ...|. | |. ..| ..                       .   .  .|||.||. || .       
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------ETGYNFKSDIWSLGCLLYEMAALQSPFYGD-----------KMNLYALCKKIDKCDY--PPLP------------ADHYTEE--------LR
        ...|..|.|.||.|..|| |    .|||||           .||.| |..|| |..|  || .             |. ..|         .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NLVAMCIHPDPNLRPDVSYVLE
.|.  .  .||. |. .. .|.
DLIRKMLQVDPEKRMTIEQCLN
Kinase NEK6.AA ULK 25-261 23 1.5e-59 204.17 In-house 1-305 (329) Show / Hide 
Range on Protein: 25-261
Range on HMM: 1-305/329
Sequence Identity: 23% (73 aa)

FAIEKRIGKGQFSEVYRARCLIN----DRVTALKKVQIFEMMDAKARND-------CIKEIDLLKSLD--------HDHVIKYLASFIEN--NELNIVLE
. . ...|||.|  ||..|. ..    . . | |......|   .  ..        ..||...| |.        | ...|..  | .   | . |..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LADAGDLSRMIKHFKK------QKRLIPERTIWKYFVQLCSALEHMHQKRVMHRDIKPANVFITA-DGK-----------VKLGDLGLGRFFSSK---TT
. . |||.  ||  ||       |. ..|  . ..| |..... ..|.....||||||.|. |.  ..|           .|..| |.......      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

AAHSLV------GTPYYMSPERIHETG----YN-FKSDIWSLGCLLYEMAALQSPFYGD--KMNLYALCKKIDK------------CDYPPL-PADHYTE
 ... |      |||.||.|. ... |    |. .|.|||||||..|||   . |||.   . .|. . | |..             ..|.  ....  .
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

ELRNL
|...|
ECKDL
Kinase NEK6.AA ULK 25-261 24 7e-59 201.93 In-house 1-300 (324) Show / Hide 
Range on Protein: 25-261
Range on HMM: 1-300/324
Sequence Identity: 24% (75 aa)

FAIEKRIGKGQFS-EVYRARCLIN---DRVTALKKVQIFEMMDAKAR-------NDCIKEIDLLKSLD---HDH--VIKYLASFIEN--NELNIVLELAD
. . ...|||.|   ||..|. ..   . . | |......| . | .       .  ..|| ..| |.   | .  ..|..  | .   | . |..|. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

AGDLSRMIKHFKK-----QKRLIPERTIWKYFVQLCSALEHMHQKRVMHRDIKPANVFITA-DGK-----------VKLGDLGLGRFFS---SKTTAAHS
 |||.  ||  ||      |. ..|  . ..| |.|... ..|.. ..||||||.|  |.  ..|           .|..| |.....       .  ..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

LV------GTPYYMSPERIHETG----YN-FKSDIWSLGCLLYEMAALQSPFYGD--KMNLYALCKKIDK-------CDYPPLPAD------HYTEELRN
.|      |||.||.|. ... |    |. .|.|||||||..|||   . ||...  . .||   | |..         . |.. .      .  .|...
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

L
|
L
Kinase NEK6.AA Ciliate-E2 25-275 21 7.5e-58 197.16 In-house 1-354 (365) Show / Hide 
Range on Protein: 25-275
Range on HMM: 1-354/365
Sequence Identity: 21% (80 aa)

FAIEKRIGKGQFSEVYRARCLINDRVTALK-------------KVQIFE----MMDAKARNDCIKEIDLLK----------------SLDHDHVIKYLAS
. . | ||.|.|. ||...   ...  |.|             ||.|..    .|  .  .   .||....                .|.|...||.  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FI--ENNELNIVLELADAGDLSRMIKHF-KKQKRLIP------ERTIWKYFVQLCS---------------ALEHMHQKR-VMHRDIKPANVFITADGKV
|.   .| . .|.|... |||   ||.. ||..  |.      |. | ... |...               |||..|.|  ..|||||| |...     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLGDLGLGRFFSSKTT-------------------------------AAHSLVGTPYYMSPERIH---------ETGYNFKSDIWSLGCLLYEMAALQSP
|. |.|| .... .                                  .....|||.||.|| .          ..||..|.||||||..||||   . |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYGDKMNLYALCKKID-KCDYPPL--------------PADHYTEELRNLVAM----CIHPDPNLRPD
|         . .... |.|.|.                 .. ..|  .|       ..  ||. |..
F---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT
Kinase NEK6.AA NEK2 25-285 30 2.2e-57 191.75 In-house 1-319 (319) Show / Hide 
Range on Protein: 25-285
Range on HMM: 1-319/319
Sequence Identity: 30% (98 aa)

FAIEKRIGKGQFSEVYRARCLINDRVTALKKVQIFEMMDAKARNDCIKEIDLLKSLDHDHVIKYLASFI--ENNELNIVLELADAGDLSRMIKHFKKQKR
  . . ||.| |  ..  |     .. . |  .  . |. | .   . |. .|. | |  ...|    |  .|  | || |    |||| |||. .|...
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEIC-YGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQ

LIPERTIWKYFVQLCSALEHMHQ------------------KR---VMHRDIKPANVFITADGK------------------------------------
 ..|  ||. . |||.||   |                   .    ..||||||||.|  .|.                                     
YMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYS

---VKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHETGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYALCKKIDKCDYPPLPADHYTEELRNLV
   ||||| || |     |  ||. |||||||||| .|   || ||||||.|||.|||.||  || .   |  .|  || .  . ..|.  | ..|  ..
QVVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQA--TNQAQLQEKIKQGHFRRIPY-QYSRHLNEII

AMCIHPDPNLRPDVSYVLEVAKR
.  |  |.  || .   |.    
HFMINVDHYHRPSIEEILQHPQI
Kinase NEK6.AA TyrKc 25-283 20 1.2e-24 89.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-283
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

FAIEKRIGKGQFSEVYRARCLINDRVTALKKVQIFEMMDAKARNDCIKEIDLLKSL--DHDHVIKYLASFIEN-------NELNIVLELADAGDLSRMIK
   .| .| |.| |||...     .  | |...         | | ..|. ....|  .|..... ..  ..          | ||.|... |||   ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

HFKKQKRLIPERTIWKYFVQLCSALEHMHQKRVMHRDIKPANVFITADGKVKLGDLGLGRFFSSK--------TTAAHSLVGTP-----YYMSPERIHET
  ...   .. ..  .. .| ..  |. |.|.. |||.   |. ..... || .| || |.  ..        .  . .  |.        |.|| | . 
KHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

GYNFKSDIWSLGCLLYEMAALQSPFYGD----KMNLYALCKKIDKCDYPPLPAD-------HYTEELRNLVAMCIHPDPNLRPDVSYVLEVA
 ...|||.|| | ...|.  .  . | .    .|. . . ..... ...| |..       . ..|. ..  .| | ||. ||  | . |  
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase NEK6.AA Pkinase_Tyr 25-220 23 4.3e-20 68.67 Pfam 1-207 (270) Show / Hide 
Range on Protein: 25-220
Range on HMM: 1-207/270
Sequence Identity: 23% (49 aa)

FAIEKRIGKGQFSEVYRARCL----INDRVTALKKVQIFEMMDAKA--RNDCIKEIDLLKSL-DHDHVIKYLASFI-ENNE--LNIVLELADAGDLSRMI
  . | .|.|.| |||....      ..   | |..   |  . ..  | | ..|. ..|.| .|........  . .     . ||.|..  |||    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK--EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KHFKKQKRLIPERTIWKYFVQLCSALEHMHQKRVMHRDIKPANVFITADGKVKLGDLGLGRFF--SSKT-TAAHSLVGTPYYMSPERIHETGYNFKSDIW
.  . .|. ..  .. .. .| ....|. ..|.  |||.   |. .| ...|| .| || |     .   .....       |.|| |..  .. |||.|
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SLGCLLYEM
| | |..|.
SFGVLMWEI