Gene NEK1c (Sea Urchin)

NEK1c

Species: Sea Urchin
Alias: Spk172, SPU_017790, NEK1c
External Links: Sea Urchin Project Link ,
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
NEK1c.AA Protein None 876 None Fasta, JSON
NEK1c.kin_dom Protein Kinase Domain None 259 None Fasta, JSON

Protein domain

Protein domains of NEK1c.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase NEK1c.AA NEK1 4-262 50 3e-189 635.0 In-house 1-276 (276) Show / Hide 
Range on Protein: 4-262
Range on HMM: 1-276/276
Sequence Identity: 50% (140 aa)

YSYQKVLGMGNFGKAWLVRSRESRRPYVIKEINVVCMGEKERERAVNEVAILGRLRHVNIIRYREAFVAGGGGILAIVMEYGDGGDLARKIEEAKLSGQS
|.|.|..|.|.|||||||...|....||||||||..|.|||||...||||||....|.||..|.|.|...|.|||.|||||.|||||..||...|..|..
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

ISAPQILNWFVQLCLALYYMHSEKVLHRDLKPSNLFLT--SKG---------------LIKVGDFGISKMLQHTLDHASTTIGTPYYLSPEICQKQPYNQ
.|..||..||.|.||||...|..|.||||.|..|.|||  ..|               |.|.|||||..||.||...|.|.|||||||||||||..|||.
FSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEICQNKPYNN

KSDMWAAGCILYELVTLTRPFEGHAFPTLIMRILRGLYTPIPRTYGTVIEELVTVLLSVNPGLRPSAHAILTSHSM
|||.|..||.||||.||..|||......|...|..|.|.|||..|......||......||..|||...||.....
KSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase NEK1c.AA NEK 4-262 44 2e-145 489.39 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-262
Range on HMM: 1-286/286
Sequence Identity: 44% (126 aa)

YSYQKVLGMGNFGKAWLVRSRESRRP-----YVIKEINVVCMGEKERERAV-NEVAILGRLRHVNIIRYREAFVAGGGGILAIVMEYGD-GGDLARK---
| ..|..| |.|||...||...  .      ||.|.||. .| |||.. |. ||| || .|.| ||..|...|.  ... | ||||| . ||||..|   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IEEAKLSGQSISAPQILNWFVQLCLALYYMHSE-----KVLHRDLKPSNLFLTSKGL----IKVGDFGISKMLQHTLDHAST-TIGTPYYLSPEICQKQP
|.. | .|. ..  ||..||.|.||||.|||..     |.||||.||.|.|||...     .|.|||||||.|.|| |.|.|  .|||||.|||.|| .|
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKP

YNQKSDMWAAGCILYELVTL--TRPFEGH--AFPTLIMRILRG-LYTPIPRT--YGTVIEELVTVLLSVNPGLRPSAHAILTSHSM
||.|||.|. ||.|||..||   .|||..   .| |.|.| .|  | ||| .  | .   .|.. .| ..| .|||.  ||    .
YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase NEK1c.AA NEK8 6-266 39 1.4e-102 293.67 In-house 1-278 (278) Show / Hide 
Range on Protein: 6-266
Range on HMM: 1-278/278
Sequence Identity: 39% (113 aa)

YQK--VLGMGNFGKAWLVRSRESR--RPYVIKEINVVCMGEKERERAVNEVAILGRLRHVNIIRYREAFVAGGGGILAIVMEYGDGGDLARKIEEAKLSG
| .  |.| | || .|| | .|       ..|.||.  | ||||  | ||. .| .| | ||| | . |     . | |.||| ||| |...| . .  .
YERIRVVGRGAFGICWLYRRKEDQSHHLVIWKQINMHRMSEKERQMAQNEIQVLSMLQHPNIISYYDHFME--DNTLMIEMEYADGGTLYQMIQHQQ--N

QSISAP-----------------QILNWFVQLCLALYYMHSEKVLHRDLKPSNLFLTSK-GLIKVGDFGISKMLQHTLDHASTT---IGTPYYLSPEICQ
 . .                   .||  |.| |.|. .||.. .||||||. | |.|   ...|.||||||| .  |  |..||   .|||||.|||.|.
KLFEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIGDFGISKIMN-TKYHMQTTKTVVGTPYYMSPEMCE

KQPYNQKSDMWAAGCILYELVTLTRPFEGHAFPTLIMRILRG-LYTPIPRTYGTVIEELVTVLLSVNPGLRPSAHAILTSHSMRPFV
 .|||||||||| ||.|||. .| | ||.   | |.. | ..  |.||.  |      ||. .|.. |  |||| .|.     .| .
GKPYNQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIMQCRAYEPISDHYSNEMRMLVHNCLQQDPEQRPSASQIM----AMPLC
Kinase NEK1c.AA NEK4 4-266 41 1.5e-94 320.38 In-house 1-257 (257) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-257/257
Sequence Identity: 41% (109 aa)

YSYQKVLGMGNFGKAWLVRSRESRRPYVIKEINVVCMGEKERERAVNEVAILGRLRHVNIIRYREAFVAGGGGILAIVMEYGDGGDLARKIEEAKLSGQS
| . || | | .|  ||||.|  .. ||.| ..      .||  |  |. .| .|.| ||. | | .  . | .| ||| . .|||| ||  . |  .| 
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQK--NQF

ISAPQILNWFVQLCLALYYMHSEKVLHRDLKPSNLFLTSKGLIKVGDFGISKMLQHTLDHASTTIGTPYYLSPEICQKQPYNQKSDMWAAGCILYELVTL
..  |...||||  .|| |||  ..||||||  |.||| | .||.||||||. |.   | |.| ||||||.|||.   .||. |||.|. || .||..||
LEEYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITL

TRPFEGHAFPTLIMRILRGLYTPIPRTYGTVIEELVTVLLSVNPGLRPSAHAILTSHSMRPFV
   |.    . || .|. |   |.|. | . . .||  .|.  |  |||   |.      |..
KHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIF----QMPYI
Kinase NEK1c.AA S_TKc 4-266 28 7.9e-77 262.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-266
Range on HMM: 1-231/231
Sequence Identity: 28% (78 aa)

YSYQKVLGMGNFGKAWLVRSRESRRPYVIKEINVVCMGEKERERAVNEVAILGRLRHVNIIRYREAFVAGGGGILAIVMEYGDG--GDLARKIEEAKLSG
|   ...| | ||| ...| ... | . ||.|.         |.. .|..|| . .| ||... ..|.    . | .|||| ||  ||| . |.. .  |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

--QSISAPQILNWFVQLCLALYYMHSEKVLHRDLKPSNLFLTSKGLIKVGDFGISKMLQHTLDHASTTIGTPYYLSPEICQKQPYNQ-KSDMWAAGCILY
  . ..  ..  .. |.|.|| |.|| ...||||||.|..|..   ||..|||... |       .| .|||.|..||..   .|.  |.|.|. |||||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELVTLTRPFEGHAFPTLIMRILRGLYTPIPRTYGTVIEELVTVLLSVNPGLRPSAHAILT--SHSM-RPFV
|...   ||.    . .......               ...  .| ..|  ||.|  .|.  .. .  |..
EMLCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NEK1c.AA Pkinase 4-259 26 2.5e-69 241.46 Pfam 1-290 (293) Show / Hide 
Range on Protein: 4-259
Range on HMM: 1-290/293
Sequence Identity: 26% (78 aa)

YSYQKVLGMGNFGKAWLVRSRESRRPYVIKEINVVCMGEKERERAVN--EVAILGRLRHVNIIRYREAFVAGGGGILAIVMEYGDGG----DLARKIEEA
|   ...| |.||. .. . . ... ...|.|...   .........  |..|. ||.| ||.|....|    .. . .|||| .||    ||.. |.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST-

KLSGQSI--SAPQILNWFVQLCLALYYMHSEKVLHRDLKPSNLFLTSKGLI----KVGDFGISKML-QHTLDHASTTIGTPYYLSPEICQ-KQPYNQKSD
  .. ..  |  .. ... |.. .|.|.||....||||||.|... ..| |    |..|||..| .       ..|  |||.|..||...  |.| .|.|
-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

MWAAGCILYELVTLTRPFEGH----AFPTLIMRILRGLYTPIPRTYG-----------------------TVIEELVTVLLSVNPGLRPSAHAILTS
||..||||||...   || ||       . . .| | ...|... .                            .... .| ..|  ||.|. || .
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH
Kinase NEK1c.AA NEK-Unclassified 6-262 35 3.9e-67 221.21 In-house 1-258 (258) Show / Hide 
Range on Protein: 6-262
Range on HMM: 1-258/258
Sequence Identity: 35% (93 aa)

YQKV--LGMGNFGKAWLVRSRESRRPYVIKEINVVCMGEKERERAVNEVAILGRLRHVNIIRYREAFVAGGGGILAIVMEYGDGGDLARKIEEAKLSGQS
| |.  || |  |  .|||   |.|  ... |       | . .  | . ||  |||  |. | ..|       |    .| |||.| |.|         
YDKITTLGQGGGGAVYLVRHQISKR-HLVQQISK----RKKKKKRQNKIIILSQLRHPHIVTYHDSFFE--NAKLFYTQDYCDGGNLDRRIQKHRKKNEP

ISAPQILNWFVQLCLALYYMHSEKVLHRDLKPSNLFLTSKGLIKVGDFGISKMLQHTLDHASTTIGTPYYLSPEICQKQPYNQKSDMWAAGCILYELVTL
.    |  |..|.  |. | |. |..||||||.| |||   ..  ||||||. . || | | |..||. ..|||.||.|||| .|| |. |||.||. | 
FDEGRIMQWCIQMIMAVQYIHQRKIIHRDLKPQNIFLTDDDTVSMGDFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTC

TRPFEGHAFPTLIMRILRGLY------TPIPRTYGTVIEELVTVLLSVNPGLRPSAHAILTSHSM
   |  |    . | | ..         |. .|| |   .... .|  |.  ||||  |.     
EPFFDTHNMGEVYMKIKQDDNRLEEALEPVSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI
Kinase NEK1c.AA NEK2 4-262 30 1.3e-65 219.92 In-house 1-319 (319) Show / Hide 
Range on Protein: 4-262
Range on HMM: 1-319/319
Sequence Identity: 30% (98 aa)

YSYQKVLGMGNFGKAWLVRSRESRRPYVIKEINVVCMGEKERERAVNEVAILGRLRHVNIIRYREAFVAGGGGILAIVMEYGDGGDLARKIEEAKLSGQS
|   ...| | ||.   ||  .  .  | |||.   |.|||.   |.|. ||  |.| ||.||    .      | |||||  ||||.  |  ..   | 
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

ISAPQILNWFVQLCLALYYMHS---------------------EKVLHRDLKPSNLFLTSKGL-------------------------------------
.  . |.  . |||.||.  |                      . .||||.|| |.|| ...                                      
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

--IKVGDFGISKMLQHTLDHASTTIGTPYYLSPEICQKQPYNQKSDMWAAGCILYELVTLTRPFEGHAFPTLIMRILRGLYTPIPRTYGTVIEELVTVLL
  .| ||||  .||.|    | | .||||| |||  . |.|| ||| |. ||..||. .|  ||.. ..  |   |  | . .||  | .   |...  .
VVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMI

SVNPGLRPSAHAILTSHSM
 |..  |||   || .   
NVDHYHRPSIEEILQHPQI
Kinase NEK1c.AA CAMK 9-257 19 1.6e-59 190.18 In-house 1-420 (425) Show / Hide 
Range on Protein: 9-257
Range on HMM: 1-420/425
Sequence Identity: 19% (81 aa)

VLGMGNFGKAWLVRSRESR------------RPYVIKEINVVCMG--------------------------EKERERAVNEVAILGR-------LRHVNI
.|| |.|||  |.. ...             . . || |.   .                           .| |..  .|..|. .       |.| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRYREAFV------------AGGGG------ILAIVM---EYGDGG----DLARKIEEAKLSG-----------QSISAPQILNWFVQLCLALYYMHSEK
|.  |..                 .       . .||   || .||    ||  .| | .  |             ..  .   .| |.| |. |.|| .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VLHRDLKPSNLFLTSK-----------------GLIKVGDFGISKMLQHTL-----------------------DHASTTIGTPYYLS-PEICQK-----
. |||||| |. |...                 . ||. ||| ......                         .  .|  |||.| . ||. ..     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------QPYNQKSDMWAAGCILYELVTLTRPFEGH-------------AFPTLIMRILRGLYTPIPRTYGTV-----------------------IE
         ..|..|.|||..|.||| ... . ||.|                . |  .|..| |. .|    ..                         
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

ELVTVLLSVNPGLRPSAHAIL
 |.  .| |.|  |.... .|
DLIRKMLQVDPEKRMTIEQCL
Kinase NEK1c.AA NEK11 4-262 38 2.9e-58 199.9 In-house 1-259 (259) Show / Hide 
Range on Protein: 4-262
Range on HMM: 1-259/259
Sequence Identity: 38% (101 aa)

YSYQKVLGMGNFGKAWLVRSRESRRP---YVIKEINVVCMGEKERERAVNEVAILGRLRHVNIIRYREAFVAGGGGILAIVMEYGDGGDLARKIEEAKLS
|  |. || | ||  .||  .  .|     |.||| |  .   |   |  |  .| || |  |.|.  .|.        |. || .| ||  .| | |  
YVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANVEAQLLSRLHHPAIVRFHASFME--QDNFCIITEYCEGRDLDYRIQEYKQA

GQSISAPQILNWFVQLCLALYYMHSEKVLHRDLKPSNLFLTSKGLIKVGDFGISKMLQHTLDHASTTIGTPYYLSPEICQKQPYNQKSDMWAAGCILYEL
|.  .  ||. ||.|| |   |||  ..||||||  |.||    |.|.||||.|..|    | | |  ||| |.|||  . | |  |||.|.  |||||.
GKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNN-LLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEM

VTLTRPFEGHAFPTLIMRILRGLYTPIPRTYGTVIEELVTVLLSVNPGLRPSAHAILTSHSM
  .   | |  |  ....|  |    .|  |   .  ..  .|  || |||||  ||    |
CCMDHAFAGSNFLSIVLNIVEGDTPSLPDRYPRELNTIMERMLNKNPSLRPSAIDILKIPYM
Kinase NEK1c.AA NEK6 4-253 34 5.4e-56 182.68 In-house 1-252 (252) Show / Hide 
Range on Protein: 4-253
Range on HMM: 1-252/252
Sequence Identity: 34% (87 aa)

YSYQKVLGMGNFGKAWLVRSRESRRPYVIKEINVV-CMGEKERERAVNEVAILGRLRHVNIIRYREAFVAGGGGILAIVMEYGDGGDLARKIEEAKLSGQ
.   | .| | |   .  .    ...  .| . .   | .| |.  . |. .| .| |.|.|.| ..|.      | ||.|  | ||..| |   |  . 
FQIEKKIGKGQFSEVYRAQCLWDDKHVALKKVQIFEMMDAKARQDCIKEIDLLKQLNHPNVIKYYASFIE--NNELNIVLELADAGDMSRMIKHFKKQKR

SISAPQILNWFVQLCLALYYMHSEKVLHRDLKPSNLFLTSKGLIKVGDFGISKMLQHTLDHASTTIGTPYYLSPEICQKQPYNQKSDMWAAGCILYELVT
 |    |  .||||| ||  ||| .|.|||.|| | |.|..| .|.|| |. .        |   .|||||.|||  . . || |||.|. ||.|||.  
LIPERTIWKYFVQLCSALEHMHSKRVMHRDIKPANVFITANGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAA

LTRPFEGHAFP--TLIMRILRGLYTPIP-RTYGTVIEELVTVLLSVNPGLRPSA
|  || |      .|  .| .  | |.|   | . . .||.. .  .| .||  
LQSPFYGDKMNLYSLCKKIEQCDYPPLPADHYSEQLRQLVCMCIHPDPEWRPDI
Kinase NEK1c.AA Ciliate-E2-Unclassified 4-209 23 1.9e-47 162.67 In-house 1-272 (352) Show / Hide 
Range on Protein: 4-209
Range on HMM: 1-272/352
Sequence Identity: 23% (65 aa)

YSYQKVLGMGNFGKAWLVRSRESRRPY-------VIKEINVVCMGEKERERAVNEVAILGR----------------LRHVNIIRYREAFVAGGGGILAI
|  .|..| |.||| .... ..    |       .|.....  . .|. |   .. ..  .                | | ....... ..      . |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VMEYGDGGDLARKIE-------------EAKLSGQSISAPQIL-----NWFVQLCLALYYMHSEK-VLHRDLKPSNLFLTSKG---LIKVGDFGISKMLQ
|||| .||||   |.             . ..... ..  |..     ..| |....| |.|... ..|||.||.|......|    ||. |||||| .|
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

------HTL---------DHASTTIGTPYYL----SPEICQKQPYN----QKSDMWAAGCILYELVTLTRPFEG
      ..          ....|..|||.|.    .||. |.| |.     |.|.|. |.||||... ..||..
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYD
Kinase NEK1c.AA TyrKc 4-262 20 2.1e-16 42.44 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-262
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

YSYQKVLGMGNFG---KAWLVRSRESRRPYVIKEINVVCMGEKERERAVNEVAILGRL--RHVNIIRYREAFVAGGG------GILAIVMEYGDGGDLAR
 .  |.|| |.||   |. .       ..  .| ..  .     ||   .|  |. .|  .| ||.|   . .  .|      . | ||||| ..|||  
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLY-GVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

KIEEAKLSGQSISAPQILNWFVQLCLALYYMHSEKVLHRDLKPSNLFLTSKGLIKVGDFGISKMLQHT--------LDHASTTIGTP-----YYLSPEIC
 . . .     .. .. |.. .| .    | || .. ||||   |  ..... .|..||| |. . .           ..... |.        ..||  
YLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

QKQPYNQKSDMWAAGCILYELVTL-TRPFEG-----HAFPTLIMRILRGLYTPIPRT--------YGTVIEELVTVLLSVNPGLRPSAHAILTSHSM
..  .. ||| |. |  ..|. |.   | .|          .| .. .| . |.|            . . .. .     .|  ||.  .|   . .
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase NEK1c.AA Pkinase_Tyr 4-160 24 2.1e-11 39.23 Pfam 1-164 (270) Show / Hide 
Range on Protein: 4-160
Range on HMM: 1-164/270
Sequence Identity: 24% (41 aa)

YSYQKVLGMGNFGKAWLVRSR----ESRRPYVIKEINVVCMGEKE--RERAVNEVAILGRL-RHVNIIRYREAFV-AGG-GGILAIVMEYGDGGDLARKI
 .  |.|| |.||. .. . .    . . |  .| ..     ...  ||   .|..|.  | .| ||.|.  . .  |. .  . |||||  .|||    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYL

EEAKLSGQSISAPQILNWFVQLCLALYYMHSEKVLHRDLKPSNLFLTSKGLIKVGDFGISKMLQHT
 . . ..|... ...|.. .| . .. | .| .  ||||   |  .|... .|..||| .. ....
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYND