Gene NEK10 (Sea Urchin)

NEK10

Species: Sea Urchin
Alias: Spk176, NEK10, SPU_018375
External Links: Sea Urchin Project Link ,
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK10

Sequence

Name Sequence Type Origin Length Description Download
NEK10.AA Protein None 758 None Fasta, JSON
NEK10.kin_dom Protein Kinase Domain None 231 None Fasta, JSON

Protein domain

Protein domains of NEK10.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Arm NEK10.AA Arm 204-239 38 0.000927 16.43 Pfam 1-36 (41) Show / Hide 
Range on Protein: 204-239
Range on HMM: 1-36/41
Sequence Identity: 38% (14 aa)

NVKQRDWLIACGAHRPLVMLLSASDVMVLHCSLYAL
| .|.. .| ||. .||| ||. .|..|.  .. ||
NPEQKQAVIQCGCVPPLVQLLHHPDEEVQENACWAL
Arm NEK10.AA Arm 245-285 29 0.03467 11.06 Pfam 1-41 (41) Show / Hide 
Range on Protein: 245-285
Range on HMM: 1-41/41
Sequence Identity: 29% (12 aa)

SPEPRAIIGELYCVETLLRILQDYDILSKKLAAWLLKVLCL
.||... . .. ||. |.. |.. |   .. |.| |  || 
NPEQKQAVIQCGCVPPLVQLLHHPDEEVQENACWALWNLCA
Arm NEK10.AA Arm 298-326 20 0.00282 14.78 Pfam 13-41 (41) Show / Hide 
Range on Protein: 298-326
Range on HMM: 13-41/41
Sequence Identity: 20% (6 aa)

GMPILLSILHSDNISLLCDVVWCIAQLAQ
..|.|.. ||... .......|..  |. 
CVPPLVQLLHHPDEEVQENACWALWNLCA
Arm NEK10.AA Arm 327-353 25 0.711538 6.58 Pfam 1-27 (41) Show / Hide 
Range on Protein: 327-353
Range on HMM: 1-27/41
Sequence Identity: 25% (7 aa)

DQDASNDVRSMGGIPLLLALLHDREFS
...    |. .|..|.|. |||.....
NPEQKQAVIQCGCVPPLVQLLHHPDEE
Arm NEK10.AA Arm 391-405 26 36.983985 0.72 Pfam 27-41 (41) Show / Hide 
Range on Protein: 391-405
Range on HMM: 27-41/41
Sequence Identity: 26% (4 aa)

SLKSACCAALTELVR
... ..|.||. |..
EVQENACWALWNLCA
Kinase NEK10.AA NEK10 527-757 72 1.4e-198 660.59 In-house 1-237 (279) Show / Hide 
Range on Protein: 527-757
Range on HMM: 1-237/279
Sequence Identity: 72% (173 aa)

YLVYEHLGTGAFGSVYKVKKNAGGN------FLALKEISFNNPAVGRTAKEKEKSIESIISELSIVKEHMRHPNVVRYYRTFTEPQVEKMYIIMELIEGA
|.||.||||||||.||||.|.|...      .||.|||...|||.|...||..||||..||||.|.||.|||||.|||||||.|||...|||.||||||.
YEVYDHLGTGAFGCVYKVRKKAQQHSENPAKLLAMKEIFMHNPAFGKNDKERDKSIEDMISELKIIKEQMRHPNIVRYYRTFVEPQNHRMYIVMELIEGC

PLYEHFNSLKEKNENFSEERIWHIFIQIVLALRYLHKEKKIVHRDLTPNNIMLGERDRVTITDFGLARARQPDASKMTSVVGTILYSCPEIVQSTPYGEK
||||||||.|||...|.||||||.|||..||||||||||.||||||||||||.|..|||||||||||...|||.||||||||||||||||||||.|||||
PLYEHFNSMKEKHHHFEEERIWHMFIQMCLALRYLHKEKQIVHRDLTPNNIMMGDKDRVTITDFGLAKQKQPDPSKMTSVVGTILYSCPEIVQSEPYGEK

ADVWAAGCVLYQMCTLKPPFYSANMLALASKVRKHFP
|||||.||.|||||||.|||||.|||.||.|...||.
ADVWAFGCCLYQMCTLQPPFYSTNMLTLAMKIVEHFY
Kinase NEK10.AA NEK 527-757 35 6.30000000001e-102 344.92 In-house 1-246 (286) Show / Hide 
Range on Protein: 527-757
Range on HMM: 1-246/286
Sequence Identity: 35% (91 aa)

YLVYEHLGTGAFGSVYKVKKNAGGNF-----LALKEISFNNPAVGRTAKEKEKSIESIISELSIVKEHMRHPNVVRYYRTFTEPQVEKMYIIMELIE-GA
| . ...| |.||.||||..   |.      ...|.|...|     . |||....     .  .......|||.|.||  | | | ....|.||  | | 
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGN----MSEKEKQNAQN----NEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGG

PLYEHFNSLKEK---NENFSEERIWHIFIQIVLALRYLHKEK----KIVHRDLTPNNIMLGERDR----VTITDFGLARARQPDASKMTS-VVGTILYSC
 ||....|.|..   ...|.|| ||..|||..|||.|.|..|    ||.|||. |.||.|  ...    | | |||...  . .... .. .|||  | .
DLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMS

PEIVQSTPYGEKADVWAAGCVLYQMCTL--KPPFYSA--NMLALASKVRKH-FP
||..|. ||..|.|.|. |||||.||||  |.||..   ||..|. |..|  ..
PEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQY
Kinase NEK10.AA Ciliate-E2 527-740 25 9.7e-60 203.74 In-house 1-296 (365) Show / Hide 
Range on Protein: 527-740
Range on HMM: 1-296/365
Sequence Identity: 25% (76 aa)

YLVYEHLGTGAFGSVYKVKKNAGGNFLALKEISFNN---------PAVGRTAKEKE--KSIESIISELSIVK---------------EHMRHPNVVRYYR
| . . .|.|.||||||.|.   ..  |.| |  ..          ..   |..    . ||.| .|..| .               |.. |||....| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

TFTEPQVEKMYIIMELIEGAPLYEHFN--SLKEKNE-----NFSEERIWHIFIQIVL---------------ALRYLHKEKKIVHRDLTPNNIMLGERDR
.| | . ...|..||...|  |... .  ..|...|     .|.|. | .|. ||.                ||.|||....|.|||. |.||..     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VTITDFGLARARQPD------------------ASKMTS-------------VVGTILYSCPEIVQSTP---------YGEKADVWAAGCVLYQMCTLKP
. |.||||..  ..|                   |....             ..||  | .|||... .         |..|.|.|..|..||.|.. ||
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PF
||
PF
Kinase NEK10.AA S_TKc 527-758 27 1.3e-57 198.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 527-758
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

YLVYEHLGTGAFGSVYKVKKNAGGNFLALKEISFNNPAVGRTAKEKEKSIESIISELSIVKEHMRHPNVVRYYRTFTEPQVEKMYIIMELIEG--APLYE
| . ...| ||||.|||....  |   |.|.|.                 |.|..|..| |.  .|||.|..| .| .   ...|..||...|    |..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFD

HFNSLKEKNEN--FSEERIWHIFIQIVLALRYLHKEKKIVHRDLTPNNIMLGERDRVTITDFGLARARQPDASKMTSVVGTILYSCPEIVQSTPYGE-KA
.  . . .  .  |.| ...... ||..|| |.|.  .|.|||| | ||.| |  .. |.||||||         |...||  |  ||..   .||  |.
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKC

DVWAAGCVLYQMCTLKPPFYSANMLAL---------------------------ASKVRK-------HFPM
|.|. ||.|| |.. .|||.    ...                           | .. .       |  .
DWWSCGCILYEMLCGYPPFP---QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase NEK10.AA CAMK 532-754 20 2.7e-56 179.57 In-house 1-361 (425) Show / Hide 
Range on Protein: 532-754
Range on HMM: 1-361/425
Sequence Identity: 20% (74 aa)

HLGTGAFGSVYKVKKN-AGG-----------NFLALKEIS-----------------FNNPAVGRTAKE-KEKSIESIISELSIVKE------HMRHPNV
 ||.|.|| |....    .|              | | |.                  ..  ... ... ..|. ... .|..| |        ..|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRYYRTFTEPQ-----------------VEKMYIIM---ELIEGA----PLYEHFNSLKEKNEN-----------FSEERIWHIFIQIVLALRYLHKEKK
.. | ..  |.                  ..||..|   |...|      |...  . . . |.           |.|.   ..| ||. |..|.|. . 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN-

IVHRDLTPNNIMLGERD-----------------RVTITDFGLARARQP-----------------------DASKMTSVVGTILYSC-PEIVQS-----
|||||| | ||.| ...                  . |.|||.|.  .|                       .  ||. ..||  | . ||....     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------TPYGEKADVWAAGCVLYQMCTLKPPFYSA-------------NMLALASKVRK
         ..||.|.|.|..|..|| | . .||||.              |.  |  |..|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMK
Kinase NEK10.AA Pkinase 527-748 31 3.8e-54 191.01 Pfam 1-226 (293) Show / Hide 
Range on Protein: 527-748
Range on HMM: 1-226/293
Sequence Identity: 31% (76 aa)

YLVYEHLGTGAFGSVYKVKKNAGGNFLALKEISFNNPAVGRTAKEKEKSIESII----SELSIVKEHMRHPNVVRYYRTFTEPQVEKMYIIMELIEGA--
| . . .| |.||.||| ..   |   |.|.|.          |..||| . ..    ||..| |.  .|||.||.|..|..    ..|..||. ||   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIK----------KRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLY

--PLYEHFNSLK-EKNENF--SEERIWHIFIQIVLALRYLHKEKKIVHRDLTPNNIMLGERDRV----TITDFGLARAR-QPDASKMTSVVGTILYSCPE
   |...   .. ... .|  ||. . ... ||. .| |.|. ..|.|||| | ||.. ... .     |.|||||.       | ||...||. |  ||
VMDLFDY---ISTWRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPE

IVQ-STPYGEKADVWAAGCVLYQMCTLKPPFYSA------NMLAL
... ...|| |.|.|..||.||.|.. .|||...      .....
VIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQM
Kinase NEK10.AA Ciliate-E2-Unclassified 527-744 22 2.5e-51 176.3 In-house 1-274 (352) Show / Hide 
Range on Protein: 527-744
Range on HMM: 1-274/352
Sequence Identity: 22% (63 aa)

YLVYEHLGTGAFGSVYKVKKNAGGNFL-----ALKEISFNNPAVGRTAKEKEKSIESIISELSIVKEHM----------------RHPNVVRYYRTFTEP
| . . .|.|.||.|||....  . ..     . | ....        | .....  |. |. ......                 ||. ....  ... 
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQ-------KQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQ

QVEKMYIIMELIEGAPLYEHFNSLKE----KNE---------NFSEERIW-----HIFIQIVLALRYLHKEKKIVHRDLTPNNIMLGERD---RVTITDF
. ...||.||..||  | .. .. |     .|.          |.|. .      ..| ||...| |||....|.|||..|.||.. .     .. |.||
DKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDF

GLARARQPD---------------ASKMTSVVGTILYS----CPEIVQSTPYG----EKADVWAAGCVLYQMCTLKPPFYSAN
|...  | .                 .|....||. |      ||. |.  |.    .|.|.|. |..||.|.. ..|||. |
GISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNN
Kinase NEK10.AA STE 527-740 25 8.6e-49 168.41 In-house 1-268 (359) Show / Hide 
Range on Protein: 527-740
Range on HMM: 1-268/359
Sequence Identity: 25% (72 aa)

YLVYEHLGTGAFGSVYKV---------KKNAG------GNFLALKEIS--FNNPAVGR--TAKEKE------KSIESIISELSIVKEHMR-HPNVVRYYR
.   | .| ||||.|||          |..        |.. | |...   .|. .    .. . |      . ...|. |..| |.    |||.|.|| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQEN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYG

TFTE----PQV-EKMYIIMELIEG---APLYE-HFNSLKEKNEN------FSEERIWHIFIQIVLA-LRYLHKEKKIVHRDLTPNNIMLGERDRVTITDF
..       .  .. .|.||...|     ...  .  .|. | |      |.|. | .|  ||. . | |||. . |.|||. | ||.|     | ..||
CYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-IIHRDIKPANILL-----VKLCDF

GLARARQPD----------------ASKMTSVVGTILYSCPEIVQS------TPYGEKADVWAAGCVLYQMCTLKPPF
|..   ...                ..| ...|||  .  ||..|        .|..|.|.|  ||..  |.| |||.
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPW
Kinase NEK10.AA NEK1 527-752 35 1.2e-45 156.34 In-house 1-233 (276) Show / Hide 
Range on Protein: 527-752
Range on HMM: 1-233/276
Sequence Identity: 35% (86 aa)

YLVYEHLGTGAFGSVYKVKKNAGGNFLALKEISFNNPAVGRTAKEKEKSIESIISELSIVKEHMRHPNVVRYYRTFTEPQVEKMYIIMELIEGAPLYEHF
|..   .| |.|| ...||. . |  ...|||....       ||.|.| .    |  |  . |.|||.|.|.  | |      ||.||  .|  |.   
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMK----MQEKEREESMN----EVAIL-AKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKI

NSLKEKNENFSEERIWHIFIQIVLALRYLHKEKKIVHRDLTPNNIMLG--ERD---------------RVTITDFGLARARQPDASKMTSVVGTILYSCP
|  | |.  |||  | | |.||.||| . |.. || |||. . || |   . .                | . ||| ||  .   .    ..||  |  |
NRQKRKGKLFSEDQIMHWFCQICLALNHIHDR-KILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSP

EIVQSTPYGEKADVWAAGCVLYQMCTLKPPFYSANMLALASKV
|| |  ||  | |.|..|||||  |||| || ..|. .|  |.
EICQNKPYNNKSDIWSLGCVLYELCTLKHPFEANNWKNLVLKI
Kinase NEK10.AA ULK 527-742 28 3.9e-43 149.61 In-house 1-254 (324) Show / Hide 
Range on Protein: 527-742
Range on HMM: 1-254/324
Sequence Identity: 28% (74 aa)

YLVYEHLGTGAFG-SVYKV--KKNAG-GNFLALKEIS---FNNPAVGRTAKEKEKSIESIISELSIVKEHM--RHPN--VVRYYRTFTEPQVEKMYIIME
| . . || |.||  |||   ||. . . . | | |.   .|.    ..  . .  ......| .|.|.    .|||  .|..|  | ...    |||||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQE--G-QYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIME

LIEGAPLYEHFNSLKE-----KNENFSEERIWHIFIQIVLALRYLHKEKKIVHRDLTPNNIMLGERDRVT------------ITDFGLARARQPD---AS
. .|  | .  .  |.     .. ..||. . ..|.||. ....||| ..|.|||. | ||.. . .  |            |.|||.|.  . .   . 
YCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHK-HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQ

KMTSVV------GTILYSCPEIVQ----STPYG-EKADVWAAGCVLYQMCTLKPPFYS
.... |      || || .|.|.|      ||.  |.|.|  ||..|.| . |.||.|
MCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFS
Kinase NEK10.AA NEK2 527-754 28 4.2e-43 142.93 In-house 1-278 (319) Show / Hide 
Range on Protein: 527-754
Range on HMM: 1-278/319
Sequence Identity: 28% (83 aa)

YLVYEHLGTGAFGSVYKVKKNAGGNFLALKEISFNNPAVGRTAKEKEKSIESIISELSIVKEHMRHPNVVRYYRTFTEPQVEKMYIIMELIEGAPLYEHF
| | . .|.| ||...||.    |  |. |||   .        |||.     .|| .| ..  .|||.||||      | .  ||.||  ||  |    
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGH------MQEKECQM--LVSECNILRQ-LKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMI

NSLKEKNENFSEERIWHIFIQIVLALRYLHK-----------------EKK---IVHRDLTPNNIMLGERDR----------------------------
   .     . || || |. |. .||.  |.                  .    | |||. | || | . .                             
KKCRKERQYMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGK

-----------VTITDFGLARARQPDASKMTSVVGTILYSCPEIVQSTPYGEKADVWAAGCVLYQMCTLKPPFYSANMLALASKVRK
           |   ||||||  . | |  .. |||  |  || ..  .| || |.|. ||..| ||.|.|||   | ..|..|...
RGSPMDYSQVVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQ
Kinase NEK10.AA ULK 527-742 29 2.9e-42 145.37 In-house 1-258 (329) Show / Hide 
Range on Protein: 527-742
Range on HMM: 1-258/329
Sequence Identity: 29% (76 aa)

YLVYEHLGTGAFGSVYKVK-KNAG---GNFLALKEIS---FNNPAVGRTAKEKEKSIESIISELSIVKEHM-------RHPNVVRYYRTFTEPQVEKMYI
| . . || |.|| ||| . |. .   .   | | |.   .|.    ..  . .  ......|  | |.         .|||.|..|  | ...    ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQE--G-QYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYI

IMELIEGAPLYEHFNSLKE------KNENFSEERIWHIFIQIVLALRYLHKEKKIVHRDLTPNNIMLGERDRVT------------ITDFGLARARQPD-
|||. .|  | .  .  |.      .. ..||. . ..|.||. ....||| ..|.|||. | ||.. . .  |            |.|||.|.  . | 
IMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHK-HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDN

--ASKMTSVV------GTILYSCPEIVQ----STPYG-EKADVWAAGCVLYQMCTLKPPFYS
  .  |.. |      || || .|.|.|      ||.  |.|.|  ||..|.| . |||||.
MEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYA
Kinase NEK10.AA TyrKc 527-756 19 2.2e-11 -38.55 SMART 1-280 (280) Show / Hide 
Range on Protein: 527-756
Range on HMM: 1-280/280
Sequence Identity: 19% (59 aa)

YLVYEHLGTGAFGSVYK--------VKKNAGGNFLALKEISFNNPAVGRTAKEKEKSIESIISELSIVKEH-MRHPNVVRYYRTFTEP-----QVEKMYI
    . || |||| |||        ||.   .                         .| ...|..| ..   .|||.|| |   |..      .| ..|
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA------------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMI

IMELIEGAPLYEHFNSLKEKNENFSEERIWHIFIQIVLALRYLHKEKKIVHRDLTPNNIMLGERDRVTITDFGLARARQPD-----ASKMTSV----VGT
.||. ..  | ..  . ..|   .. .   .. .||    .|||.  ...||||   |...||. .| |.||||.|.   |     .... ..     | 
VMEYMPHGDLKDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGK

----ILYSCPEIVQSTPYGEKADVWAAGCVLYQMCTL-KPPFYS-----------------ANMLALASK------------------------------
    |    ||  .   . .| |||. | ... ..|. ..| .                   ...                                   
TMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPT

---VRKHF
   ... |
FSEIHECF
Kinase NEK10.AA Pkinase_Tyr 573-689 30 2.8e-11 38.8 Pfam 42-160 (270) Show / Hide 
Range on Protein: 573-689
Range on HMM: 42-160/270
Sequence Identity: 30% (38 aa)

EKS--IESIISELSIVKEHMRHPNVVRYYRTFT---EPQVEKMYIIMELIEGAPLYEHFNSLKEK---NENFSEERIWHIFIQIVLALRYLHKEKKIVHR
..   .|. ..|..| |.  .|||.||.|   |   ||.  ..||.||. ..  |...   |...   ..... ... .. .||  .. ||. .|...||
HEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDLLDY---LRKHREDKQPLTMKDLLQMCWQIAKGMEYLE-SKNCIHR

DLTPNNIMLGERDRVTITDFGLARA
||   |....|   | |.||||||.
DLAARNCLVTENNVVKICDFGLARD
Kinase NEK10.AA Pkinase_Tyr 527-543 52 0.39501 4.45 Pfam 1-17 (270) Show / Hide 
Range on Protein: 527-543
Range on HMM: 1-17/270
Sequence Identity: 52% (9 aa)

YLVYEHLGTGAFGSVYK
    . || ||||.|||
ITFGKKLGEGAFGEVYK