Gene Spk371 (Sea Urchin)

Spk371

Species: Sea Urchin
Alias: SPU_010517, Spk371
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
Spk371.AA Protein None 347 None Fasta, JSON
Spk371.kin_dom Protein Kinase Domain None 75 None Fasta, JSON

Protein domain

Protein domains of Spk371.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc Spk371.AA S_TKc 60-329 16 1.8e-09 -38.08 SMART 1-231 (231) Show / Hide 
Range on Protein: 60-329
Range on HMM: 1-231/231
Sequence Identity: 16% (47 aa)

TTEGRLCKLGHFSPIRCKAGQHKVAPISVIIKKVRCYPSLTATLQMLHSKSQPFLEGIISSCLWYRQIKEEKLLVCSTYLSE--KSLSSLLD--------
 . .|.   | |.  ... ..||     | ||...   ..   .|.|..   |..  .. ..        ..| ..  |..    .| ....        
YEILRKIGKGAFG--KVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--YRRDTLEKYWIEACEAAVTLHESGILYLNWKVDHLVVTDQDRVKLCNFDYAVDIRSSRRGLRGSCSEEWRGTEVPDHVKTGLDPRI-----APPEVLN
  .   .  .|  . |.|   .|. ||..   | . . ...  ..|.| |  |  .                            .  .      .|||| 
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------------------TTFCGTPWYMAPEVL-

GDGLMP-ESDTWGLGCLLYQLYNGGCLPYPDLRHLIDDAIREKRLTEKHSKLVPASPKIQLLSEMCWKKDQMERKSPAELVT-----SLNVYK
  |  . ..| | .||.|| ..  |. |.|      .... .| .          ||    . . |..||  .| .  |. .      .  . 
--GYGKCKCDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Spk371.AA TK 237-325 15 2.7e-08 23.13 In-house 353-486 (486) Show / Hide 
Range on Protein: 237-325
Range on HMM: 353-486/486
Sequence Identity: 15% (21 aa)

PPEVLNGDG---------LMPESDTWGLGCLLYQLYNGG-CLPYPDLRH-----------LIDDAIREKRL--------TEKHSKL--VPAS--------
.||.||.             ..|| | .|.|.. ..  |   .|... .           ...   |. ||         ... .   . ..        
APECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMH

------PKIQLLSEMCWKKDQMERKSPAELVTSL
      . ...|  .||..|  .| . ..|.  |
PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Spk371.AA PDK1 238-265 42 4e-07 17.3 In-house 208-235 (307) Show / Hide 
Range on Protein: 238-265
Range on HMM: 208-235/307
Sequence Identity: 42% (12 aa)

PEVLNGDGLMPESDTWGLGCLLYQLYNG
||.|..    |..| |.|||..||.  |
PELLTDKECTPSCDIWALGCIIYQMVAG
Kinase Spk371.AA Pkinase 236-325 16 5.1e-07 25.89 Pfam 178-293 (293) Show / Hide 
Range on Protein: 236-325
Range on HMM: 178-293/293
Sequence Identity: 16% (19 aa)

APPEVLN-GDGLMPESDTWGLGCLLYQLYNGGCLPYPDL----RHLIDDAIREKRLTEKHSKLVPAS---------------------PKIQLLSEMCWK
..|||.. | .  |..| |..||.||.... | .|.|.     . . .... ....  . .   | .                     .  . . . |..
MAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

KDQMERKSPAELVTS--L
||  .| ...... .  .
KDPKKRPTAEQILQHPWF
Kinase Spk371.AA CAMK 236-260 30 1.6e-05 12.94 In-house 286-325 (425) Show / Hide 
Range on Protein: 236-260
Range on HMM: 286-325/425
Sequence Identity: 30% (12 aa)

AP-PEVLNG--------------DGLMPESDTWGLGCLLY
.. ||||||              ..  |..| | .|..||
MAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILY
Kinase Spk371.AA PLK2 238-260 60 3.3e-05 12.42 In-house 172-194 (257) Show / Hide 
Range on Protein: 238-260
Range on HMM: 172-194/257
Sequence Identity: 60% (14 aa)

PEVLNGDGLMPESDTWGLGCLLY
|||||  |  .||| | |||  |
PEVLNRQGHSCESDIWALGCIMY
Kinase Spk371.AA Ciliate-E2-Unclassified 235-272 33 8.8e-05 12.55 In-house 232-272 (352) Show / Hide 
Range on Protein: 235-272
Range on HMM: 232-272/352
Sequence Identity: 33% (14 aa)

IAPPEVLNGDGLMPE----SDTWGLGCLLYQLYNGGCLPYPD
...|||| | .   .    .| |.||..||..  |  .|..|
YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY-YPFYD
TyrKc Spk371.AA TyrKc 60-325 14 9.3e-05 -145.74 SMART 1-280 (280) Show / Hide 
Range on Protein: 60-325
Range on HMM: 1-280/280
Sequence Identity: 14% (47 aa)

TTEGRLCKLGHFSPI-RCKAGQHKVAPISVIIKKVRCYPSLTATLQMLHSKSQPFLEG---------IISSCLWYRQIKE-------EKLLVCSTYLSEK
 | |.    |.|  . ....       | | .|... .      ......  .   .          ..  |.     ..       | |..   | .  
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCT-----QQGRNFMYIEPLMIVMEYMPHG

SLSSLLDYRRDTLEKYWIEACEAAVTLHE------SGILYLNWKVDHLV----------VTDQDRVKLCNFDYAVDIRSS-RRGLRGSCSEEWRGTEVPD
.| . | ..|..             .|..      .|  ||  |  ...          |... .|| . |  . || .  ..|            |  |
DLKDYLRKHRPK---------LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG------------ESKD

HVKTGL--DPR--I----APPEVLNGDGLMPESDTWGLGCLLYQLYNGGCLPYPD-------LRHLIDDAIREKRLTEKHSKLVP-----ASPKIQLLSE
  ..    . .  .     .||..|     ..|| |  | ... ..  |  |||.        ...| .  . .|.   .. . |     .....  . .
YYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMK

MCWKKDQMERKSPAELVTSL
.||. |  .| . .|..  .
QCWHEDPEDRPTFSEIHECF
Kinase Spk371.AA RTKH 225-271 40 0.000134 11.57 In-house 174-220 (276) Show / Hide 
Range on Protein: 225-271
Range on HMM: 174-220/276
Sequence Identity: 40% (19 aa)

DHVKTGLDPRIAPPEVLNGDGLMPESDTWGLGCLLYQLYNGGCLPYP
|  . ||  |   |||.        || |  | ||| |.  | .|||
DSCQEGLPMRWLAPEVISSGVFSYASDVWSFGVLLYELFTHGGMPYP
Kinase Spk371.AA TKL 237-325 18 0.000208 11.8 In-house 241-364 (364) Show / Hide 
Range on Protein: 237-325
Range on HMM: 241-364/364
Sequence Identity: 18% (23 aa)

PPEVLNGDGLMPES----------------DTWGLGCLLYQLYNGGCLPYPDLRHLIDD------AIREKRLTEKHSKLVP--------------ASPKI
.||||.|..  .|                 | .  | .|. ..  .|.|| |. .   .      .. ...  ...  ..|              . | .
APEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEIL-TRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSM

QLLSEMCWKKDQMERKSPAELVTSL
  | ..||. |  .| |  |..  |
KKLMQDCWDHDPEKRPSFQEILKRL
Kinase Spk371.AA RTKC 250-270 42 0.000283 9.87 In-house 188-208 (261) Show / Hide 
Range on Protein: 250-270
Range on HMM: 188-208/261
Sequence Identity: 42% (9 aa)

SDTWGLGCLLYQLYNGGCLPY
|| |..| |.| .|. . .||
SDVWAFGILMYEIYTKAEMPY
Kinase Spk371.AA PLK1 238-265 50 0.000287 9.64 In-house 168-195 (253) Show / Hide 
Range on Protein: 238-265
Range on HMM: 168-195/253
Sequence Identity: 50% (14 aa)

PEVLNGDGLMPESDTWGLGCLLYQLYNG
|||||  |   | | | .||..| |  |
PEVLNKKGHSFEVDIWSIGCIMYILLFG
Kinase Spk371.AA NuaK 236-262 50 0.000366 6.25 In-house 165-192 (252) Show / Hide 
Range on Protein: 236-262
Range on HMM: 165-192/252
Sequence Identity: 50% (14 aa)

APPEVLNGDGLM-PESDTWGLGCLLYQL
| ||. ||     || | | || ||| .
ASPEIVNGQPYHGPEVDCWSLGVLLYTM
Kinase Spk371.AA RTKC 306-325 30 0.181848 0.46 In-house 242-261 (261) Show / Hide 
Range on Protein: 306-325
Range on HMM: 242-261/261
Sequence Identity: 30% (6 aa)

MCWKKDQMERKSPAELVTSL
.||. .  .| .  |.|. |
DCWMHTPHDRPTFSEVVHWL