Gene PLK2 (Sea Urchin)

PLK2

Species: Sea Urchin
Alias: PLK2, SPU_000468, Spk189
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: Other
Family: PLK
Subfamily: PLK2

Sequence

Name Sequence Type Origin Length Description Download
PLK2.AA Protein None 711 None Fasta, JSON
PLK2.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of PLK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PLK2.AA PLK2 90-341 67 3e-222 722.92 In-house 1-257 (257) Show / Hide 
Range on Protein: 90-341
Range on HMM: 1-257/257
Sequence Identity: 67% (174 aa)

YRRGRLLG-GGFARCYELTHLDTHYVYAGKIVPKERISKPSQREKMEREIAVHAQLRHPHIVGFHKHFQDAENIYILLELCRH----KSLLHMLKLRKHL
|.||.||| ||||||||.|..|||||||.||||..|..||.|||||||||..|.||||.|||.||.||.|..|||||||.|..    ||..||.|.|.||
YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVRHHL

TEPEVRYFMLQIIEGVRYLHSHCVIHRDLKLGNMFLTDTMGVKIGDFGLAAKLEFEGDRKRTMCGTPNYIAPEVLGKIGHSFEADVWALGCIMYTMLVGR
|||||||.|.||..|.||||..|.|||||||||.|..|.|.||||||||||.||.|....|||||||||||||||...|||.|.|.|||||||||||.||
TEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVLNRQGHSCESDIWALGCIMYTMLCGR

PPFETSSLKETYARIKHNKYHFPETLSPVAKEIISDLLSSDPEERPPLEVVIDHEFF
|||||..|||||..|.||.||.|..|||.|...|...||.|||.||.|...|.|.||
PPFETANLKETYRCIRHNHYHMPTHLSPPARHLIARMLSPDPEDRPSLDHIIRHDFF
Kinase PLK2.AA PLK 90-341 60 1.4e-190 625.72 In-house 1-258 (258) Show / Hide 
Range on Protein: 90-341
Range on HMM: 1-258/258
Sequence Identity: 60% (157 aa)

YRRGRLLG-GGFARCYELTHLDTHYVYAGKIVPKERISKPSQREKMEREIAVHAQLRHPHIVGFHKHFQDAENIYILLELCRHKSLLHMLKLR-KHLTEP
|.||..|| ||||.|||.|...|..|||.|.|||... ||.|||||..||..| ||.||.||.||..|.|.||.||.||.|...||.|..| | |.||||
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

EVRYFMLQIIEGVRYLHSHCVIHRDLKLGNMFLTDTMGVKIGDFGLAAKLEFEGDRKRTMCGTPNYIAPEVL--GKIGHSFEADVWALGCIMYTMLVGRP
||||.|.||..|..|||.|..|||||||||.||.| | |||||||||..||..|.||.||||||||||||||   |.|||.|.|.|.|||||||.|.|.|
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFETSSLKETYARIKHNKYHFPET--LSPVAKEIISDLLSSDPEERPPLEVVIDHEFF
||||...|||| |||||.|.|||   .|..||..| ..|. .|.||| .. ...|.||
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase PLK2.AA PLK1 90-341 58 3.5e-138 456.98 In-house 1-253 (253) Show / Hide 
Range on Protein: 90-341
Range on HMM: 1-253/253
Sequence Identity: 58% (149 aa)

YRRGRLLG-GGFARCYELTHLDTHYVYAGKIVPKERISKPSQREKMEREIAVHAQLRHPHIVGFHKHFQDAENIYILLELCRHKSLLHMLKLRKHLTEPE
|..|| || ||||.|||... ||. |.|||.|||. . |. ||.|| .|| .| ||.|.|||.||..| | .|.||.|||||..||. . | || .||||
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

VRYFMLQIIEGVRYLHSHCVIHRDLKLGNMFLTDTMGVKIGDFGLAAKLEFEGDRKRTMCGTPNYIAPEVLGKIGHSFEADVWALGCIMYTMLVGRPPFE
 ||.| ||.||..|||   .|||||||||.|| | . ||||||||| |.|..|.||.|.|||||||||||| |.||||| |.|..|||||..|.|.||||
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLFGQPPFE

TSSLKETYARIKHNKYHFPETLSPVAKEIISDLLSSDPEERPPLEVVIDHEFF
|..||||| |||.|.|  |. .|..|...|  .|  ||..||  | |.  |||
TKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase PLK2.AA PLK-Unclassified 90-341 49 4.2e-136 458.45 In-house 1-264 (264) Show / Hide 
Range on Protein: 90-341
Range on HMM: 1-264/264
Sequence Identity: 49% (131 aa)

YRRGRLLG-GGFARCYELTHLDTHYVYAGKIVPKERISKPSQREKMEREIAVHAQLRHPHIVGFHKHFQDAENIYILLELCRHKSLLHMLKLR-------
|.||..|| ||||.||. . ..|  .|| ||.||  . | ..|.|   || .| .| |..|| | . | | ||.|||||.| ...| ...| |       
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

KHLTEPEVRYFMLQIIEGVRYLHSHCVIHRDLKLGNMFLTDTMGVKIGDFGLAAKLEFEGDRKRTMCGTPNYIAPEVL-GKI-GHSFEADVWALGCIMYT
| |||.||... .||.... |||.. .||||||||| ||.| | |||.|||||.|||..| .|.| ||||||||||.| ||  |||.| |.|..||| ||
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT

MLVGRPPFETSSLKETYARIKHNKYHFPE--TLSPVAKEIISDLLSSDPEERPPLEVVIDHEFF
.|.|.|||||.. | || .|| |.| |||  ..|  || .| . |. .|..|| .    .| |.
LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase PLK2.AA AGC 90-341 22 6.1e-93 239.94 In-house 1-395 (395) Show / Hide 
Range on Protein: 90-341
Range on HMM: 1-395/395
Sequence Identity: 22% (90 aa)

YRRGRLLG-GGFARCYELTHL------DTHYVYAGKIVPKER-ISKPS--QREKMERE------------IAVHAQLR----------HPHIVG-FHKHF
..  ...| |.| ..|   .       ||  .|| |.. |.. | .    . |.  .|              . ....          || ||   |  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDAEN--IYILLELCR----------H-KSLLHMLK--LRKHLTEPEVRYFMLQ-------IIEGVRYLHS-HCVIHRD-LKLGNMFLTDTMGVKIGDFG
|| ..  .|...|..              ..||. .   .....|...|... .       |. .. |||| . .|||| ||. |. |..   .|. |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAAKLEFEG--------------------------------------------------DRKRTMCG--TPNYIAPEVLGKIGHSFEADVWA--LGCIMY
|. ..  .|                                                  ||  |.||  ||.|.|||.|    .....| |.  |||.||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

TMLVGRPPFETSSLK----------ETYARIK------HNKYHFP----------ETLSPVAKEIISDLLSSDPEERPP----------LEVVIDHEFF
 ||.|.|||   .            |.. .|.      ..| .||          . .|| || .|. ||  |||.|.            | . .|..|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase PLK2.AA S_TKc 90-341 33 1.9e-89 304.42 SMART 1-231 (231) Show / Hide 
Range on Protein: 90-341
Range on HMM: 1-231/231
Sequence Identity: 33% (91 aa)

YRRGRLLG-GGFARCYELTHLDTHYVYAGKIVPKERISKPSQREKMEREIAVHAQLRHPHIVGFHKHFQDAENIYILLELCRH--KSLLHMLKLRKH---
|. .|..| |.|...|  .| .|. ..| ||..          |...|||... . .||.|| .. .||| ...|. .|.| .   .|....| |..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEPEVRYFMLQIIEGVRYLHSHCVIHRDLKLGNMFLTDTMGVKIGDFGLAAKLEFEGDRKRTMCGTPNYIAPEVLGKIGHSF-EADVWALGCIMYT
   ..| ..|..| ||.... |.||| .||||||  | .|..   .||.|||||..|       .|.||||.|.|||||   |... ..|.|..|||.| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLVGRPPFETSSLKETYARIKHNKYHFPETLSPVAKEIISDLLSSDPEERPPLEVVID-------HEFF
||.|.|||.   ..... .|.          || ||..|. .|  |||.||    .         |..|
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PLK2.AA CAMK 95-341 21 3e-87 281.11 In-house 1-425 (425) Show / Hide 
Range on Protein: 95-341
Range on HMM: 1-425/425
Sequence Identity: 21% (91 aa)

LLG-GGFARCYELTHLDTH------------YVYAGKIVPKERISK-------------------------PSQREKMEREIAVHAQ-------LRHPHI
 || |.|.  .. .|  |               .| ||..|.....                         |. |....|||... .       |.||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VGFHKHFQDAEN-------------------IYILL---ELCRHK----SLLHMLKLRKH---------------LTEPEVRYFMLQIIEGVRYLHSHCV
. .. ...|...                   .|. .   |.|        |. ... ...               .|| |.|... ||...|.|.||| .
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKLGNMFLTDTM----------------G-VKIGDFGLAAKLEF-----------------------EGDRKRTMCGTPNYIA-PEVLGKIG----
.|||||. |  |.| .                . .|| |||.|.|..                        ||.  .|.|||| |.| |||| . |    
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

----------HSFEADVWALGCIMYTMLVGRPPFETS-------------SLKETYARIKHNKYHFPET------------------------LSPVAKE
          .....|.|..|.|.|.||.|.|||. .             ...|.. .|.  ||.||.                         .|. .| 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

IISDLLSSDPEERPPLEVVIDHEFF
 |. .|  |||.|. .| . .|...
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase PLK2.AA Pkinase 90-341 29 8.1e-83 286.24 Pfam 1-293 (293) Show / Hide 
Range on Protein: 90-341
Range on HMM: 1-293/293
Sequence Identity: 29% (87 aa)

YRRGRLLG-GGFARCYELTHLDTHYVYAGKIVPKERISKPSQREKME-REIAVHAQLRHPHIVGFHKHFQDAENIYILLELCRHK----SLLHMLK--LR
|..|| .| |.|...|. .| .|  ..| ||..|.....  ....   .||.... |.||.|| ..  |.|  .||. .|.|..     .| ....   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KHL--TEPEVRYFMLQIIEGVRYLHSHCVIHRDLKLGNMFLTDTMGV----KIGDFGLAAKL-EFEGDRKRTMCGTPNYIAPEVLG-KIGHSFEADVWAL
. .  .| |.. .|.||..|. |.||. .||||||. | .. ... .    ||.|||||... .  .    | ||||.|.||||.    ... ..|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCIMYTMLVGRPPFETS------SLKETYARIKHNKYHFPETLS---------------------PVAKEIISDLLSSDPEERPPLEVVIDHEFF
|||.| || |||||  .      . .. ..||.. ..||..  .                     . .|..|...|  ||..||  | .  |..|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase PLK2.AA SAK 90-341 40 1.9e-82 280.18 In-house 1-254 (254) Show / Hide 
Range on Protein: 90-341
Range on HMM: 1-254/254
Sequence Identity: 40% (104 aa)

YRRGRLLG-GGFARCYELTHLDTHYVYAGKIVPKERISKPSQREKMEREIAVHAQLRHPHIVGFHKHFQDAENIYILLELCRHKSLLHMLKLR-KHLTEP
|. . ||| ||||  |    . ||   | |.. |  . |    ... .|. .|.||.|| |.   ..|.|.  .|. ||.|.   ..  .| | .  || 
YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEE

EVRYFMLQIIEGVRYLHSHCVIHRDLKLGNMFLTDTMGVKIGDFGLAAKLEFEGDRKRTMCGTPNYIAPEVLGKIGHSFEADVWALGCIMYTMLVGRPPF
| | || ||. |. ||||| ..|||| | |. ||  | .|| |||||..|.   ..  |||||||||.||.  .  |  ..|||.|||..||.|.|||||
EARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLLIGRPPF

ETSSLKETYARIKHNKYHFPETLSPVAKEIISDLLSSDPEERPPLEVVIDHEFF
.| . |.|  ..    |  |  ||  |...|  .|  .|.||  |. |..| | 
DTDAVKNTLNKVMMAEYIMPAHLSMEAQDLIHKMLRKNPHERITLSTVLCHPFM
Kinase PLK2.AA CAMKL 90-341 27 2.2e-72 230.29 In-house 1-297 (297) Show / Hide 
Range on Protein: 90-341
Range on HMM: 1-297/297
Sequence Identity: 27% (81 aa)

YRRGRLLG-GGFARCYELTH-LDTHYVYAGKIVPKERISKPSQREKM------------EREIAVHAQLR---HPHIVGFHKHFQDAEN------IYILL
|| |. || |.|.     || . |   .| ||. |..|..  . .|.            .|||. . .|.   ||.|. .. .... |.      ||. .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCRHKS--LLHMLKLRKH----LTEPEVRYFMLQIIEGVRYLHSHCVIHRDLKLGNMFLTDTMG--VKIGDFGLAAKLE-F---EGDRKRTMCGTPNYI
|.|   .  |..... ..|    ..|.| | .  ||...| |.|||...|||.|. |  |.. .   .|| |||.... .     .|.  .| ||.|.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVLGK--IGHS-FEADVWALGCIMYTMLVGRPPFETSSLK-------ETYARIKHNKYHFP--ETLSPVAKEIISDLLSSDPEERPPLEVVIDHEFF
|||.. .    .  ...|.|..| |.|.|..|. ||.  ...       . | .|.   |..|    .|  .. .|. .|  .||.|| .. .  |...
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase PLK2.AA RSK 107-341 34 1.4e-65 224.19 In-house 19-278 (278) Show / Hide 
Range on Protein: 107-341
Range on HMM: 19-278/278
Sequence Identity: 34% (89 aa)

THLDTHYVYAGKIVPKERISKPS--QREKM-EREIAVHAQLRHPHIVGFHKHFQDAENIYILLELCRHKSLLHMLKLRKH---LTEPEVRYFMLQIIEGV
|| ||  .|| |.. |  | .    .| .| ||.|  . | .|| ||  |  ||. . .|. .|.||   |.  |. .||   ..| |... | .|.  |
THHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQ-QHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAV

RYLHSHCVIHRDLKLGNMFLTD---TMGVKIGDFGLAAKLEFE-GDRKRTMCGTPNYIAPEVLG----KIGHSFEADVWALGCIMYTMLVGRPPFET---
..||.. .||||||. |. ..|      .|. |||.. ..  . . .  | |.| .|.|||.|     . ||.  .|.| ||..||.||.|.|||     
EHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPND

SSLKETYARIKHNK--YHFP--ETLSPVAKEIISDLLSSDPEERPP-----LEVVIDHEFF
.. ||. .||...|    .|  ..||. ||..|. .|  ||. |.      .| . .|..|
NNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase PLK2.AA Ciliate-E2 90-341 23 1.2e-64 220.81 In-house 1-365 (365) Show / Hide 
Range on Protein: 90-341
Range on HMM: 1-365/365
Sequence Identity: 23% (89 aa)

YRRGRLLGGG-FARCYELTHLDTHYVY------------------AGKIVPKERISKPSQREKMEREIAVHAQLR----------------HPHIVGFHK
|   ...| | |.  |. ..  . . .                  ..||. .....| .| | ...|| .  ...                ||.|. .. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKK-NQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

HFQ--DAENIYILLELCRHKSLLHMLKLRKH-----------LTEPEVRYFMLQIIE---------------GVRYLHSHC-VIHRDLKLGNMFLTDTMG
.||  | .|||. .|.| ...|.. .| .|.           .|| |..|.| ||..               ...||||   .||||.|. | ..     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKIGDFGLAA----------------KLEFEG----------------DRKRTMCGTPNYIAPEVLG---------KIGHSFEADVWALGCIMYTMLVGR
.|| ||||.                 .. | .                .  .| ||||.| |||.|.         . |.....|.|.||.|.| || |.
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

PPFETSSLKETYARIKHNKYHFP------------------ETLSPVAKEIISD----LLSSDPEERPP-LEVVIDHEFF
|||        .  || .|. ||                  . .|. .| .|.     .|  |||.|.   | ...|..|
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase PLK2.AA TyrKc 90-341 23 1.4e-15 29.35 SMART 1-280 (280) Show / Hide 
Range on Protein: 90-341
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

YRRGRLLGGGF------ARCYELTHLDTHYVYAGKIVPKERISKPSQREKMEREIAVHAQL--RHPHIVGFHKHFQDA-------ENIYILLELCRHKSL
 . |. || |.      .. .        .  | | . ..       || . ||. .  .|  .||.|| ..    .        | ..|..|.. | .|
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

LHMLKLRKH-LTEPEVRYFMLQIIEGVRYLHSHCVIHRDLKLGNMFLTDTMGVKIGDFGLAAKLEFE------GDRKRTM---CGTP----NYIAPEVLG
.. |. ... |. ..  .|..|| .| .||||...|||||   |  ...   |||.||||. ... .      .| .|..   .|         |||.. 
KDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

KIG-HSFEADVWALGCIMYTML-VGRPPFET-----SSLKETYARIKHNKYHFPETL----------SPVAKEIISDLLSSDPEERPPLEVVIDHEFF
. |  ... |||. |  |. ..  | .| .       | .| ....|. ..  .             . . . |...    |||.||  . .  ||.|
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
Kinase PLK2.AA Pkinase_Tyr 118-234 36 3.9e-15 51.89 Pfam 34-158 (270) Show / Hide 
Range on Protein: 118-234
Range on HMM: 34-158/270
Sequence Identity: 36% (46 aa)

KIVPKERISKPSQ--REKMEREIAVHAQL-RHPHIVGFHKHFQ-DAEN--IYILLELCRHKSLLHMLKL----RKHLTEPEVRYFMLQIIEGVRYLHSHC
|.. ||  . ..|  ||.. ||...  || .||.|| ..     . |   ||| .|.. | .||. |.     ...|| ..   . .|| .|  ||.|. 
KML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN

VIHRDLKLGNMFLTDTMGVKIGDFGLA
 |||||   |  .|... |||.|||||
CIHRDLAARNCLVTENNVVKICDFGLA
POLO_box PLK2.AA POLO_box 511-574 36 1.6e-23 89.23 Pfam 1-74 (74) Show / Hide 
Range on Protein: 511-574
Range on HMM: 1-74/74
Sequence Identity: 36% (27 aa)

YSNKYGFGYQLSNKVVGVM-FNDKSRISFTPDRS-SVQYLS--TDSKVHSFPLSS------VPSRLSKKVTLLD
|..|||..|||||. |.|. |||...|   |..  .|.| .  .. . . .|||.      .|. | ||.|.|.
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK
POLO_box PLK2.AA POLO_box 623-694 44 1.2e-18 72.54 Pfam 1-74 (74) Show / Hide 
Range on Protein: 623-694
Range on HMM: 1-74/74
Sequence Identity: 44% (33 aa)

NRTGKAITMYLSNGTLQVNFFEDHTKVILSHNNNDHLVTYIN--ESRTPTTYRVLHITHHGC-TKALHTRLSYAR
 ||  .| . ||||| ||||| ||||.||..|    .||||.  .... .||.  .|. |||  . |. .| |..
YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMK-YAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK