Myo3

Species: Sea Urchin
Alias: Myo3, Spk391
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: NinaC

Sequence

Name Sequence Type Origin Length Description Download
Myo3.AA Protein None 634 None Fasta, JSON

Protein domain

Protein domains of Myo3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
MYSc Myo3.AA MYSc 16-634 36 1.5e-250 839.51 SMART 1-771 (771) Show / Hide
Range on Protein: 16-634
Range on HMM: 1-771/771
Sequence Identity: 36% (287 aa)

PVPGRV-VVSNNASMKIL-------------CASDGKTYTGSILVAVNPYKLFDDIYNIENVRRYE------GQLIGHLPPHLFAIGSGAYLRMTQTKQN
 .|     |. .. .  |                   ||.|....||||||  . ||. . ...|       |. .. .|||.|||   ||  | . |.|
MNPPKFEGVDDMCMLTYLNEPAVLHNLKKRYMNDQIYTYIGPVCIAVNPYKQLPPIYTPDVIKQYRNRKFDDGKHRYEMPPHIFAIADNAYRNMLNDKEN

QCIVISGESGAGKTESTKLIMQYLAAVNKASTNLITEQILEANPLLEAFGNAKTTRNDNSSRFGKYIEL-FFNNGLISGARTTEYLVEKSRVVRQTSGER
|||.|||||||||||.||.||||||||   ... . .|||..||.|||||||||.||.||||||||.|. | ..| |.||  . || ||||||.|. |||
QCIIISGESGAGKTENTKKIMQYLAAVSG-QVERVEQQILQSNPILEAFGNAKTVRNNNSSRFGKYMEIHFDEKGKICGAKIENYLLEKSRVVYQNKGER

NYHIFYQMLAGMSIGEKAKYGLSQ----PERYFYLNQGG-----------SSRLETRNDADDFIR----TVSAMEVLNFDPNKQETAFSILAAILHIGNL
|||||||..|| |  .| ...|..    || |.||||||            .......||..| .    |..||.|..|.   ||  |.|.|||||.||.
NYHIFYQLCAGASEEQKQEFHLKPFSHNPEDYHYLNQGGHYWNNKRHQSQCFTVDGIDDAEEFKETCEQTCNAMRVMGFSEEEQEWIFRIVAAILHLGNI

SLQNSKTQDRPDMLE----VTNEGALSGAARLLHIDPKQLEGAILYRVTETIGE---RILTPRTLEQAEDARDGIAKSLYTSLFAWLVRSINGITNQSAK
. ...  |   .  .    | .| .|. |..|| .||..|| ....|...| .|   .| .|...|||..||| .|| .|  || |.|. ||       .
EFEQGRNQ-YDNQAVCSEKVKDEEELQNACELLGVDPEDLEKWLTHRKMKTGHEGGTWITKPLNVEQAIYARDALAKAIYSRLFDWIVKRINQSM----H

MTSIAILDIFGFEVFGTNGFEQLCINYANEHLQFYFNKHIFQLEQLEYAKEKIEWQTISFV--DNQPVLDLLAKR---PTGILHILDDESNF---PKGTE
 ..| .|||.|||.|  |.|||.||||.|| || .||.|.| ||| || .|.|||  | |.  ||||..||. |.   | ||. .||.|..|   |||| 
NYFIGVLDIYGFEIFEHNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYQREGIEWTFIDFFMYDNQPCCDLIEKKGKRPMGIFSLLDEECMFHAQPKGTD

KAFVEKC-----HYHHSSNSSYGRP-----------KQPRLEFCIKHYAGRVIYQLDNVIGKNRDMLKPEVMEMFKNSRNRVLSDMFKL--LQTVEQRRS
. |.||.     | ||.... .  |           ...| .| ||||||.| |. .  . ||.| | ..... ...|.|... ..|.    ||..... 
QTFLEKLNKQDYHQHHKNHPHFSKPHKSHRCCKPKKRMGRTHFIIKHYAGDVTYNVEGWLEKNKDTLFDDLIQLMQSSKNPFIKQLFPEYEDQTSQTPQE

MMGASGPSG--------------MRKMRPSTVATRFNESLLELINNMNKCHPFFVRCIKPNEEKAPMLFDTPIVLSQLRYSGMLETVRIRRNGFPIRMTF
. .  | ..              | | |..||...|  .| ||....|.|||...||||||||| |  || . || |||..|.||..|||| ||| |...
KSS-QGKNKSRRKKRMMQMKKTCMQKKRFPTVGFQFK-QLNELMETLNSCHPHYIRCIKPNEEKKPWDFDDDLVLHQLRCCGVLENIRIRRAGFPYRWPY

---------LSF----------------------------------------------------------------MNR
         |..                                                                ..|
QEFYQRYKMLCPPTWPNWGNPWKNQLFGDPKKACEAILQQLGEYIQHQNWDPDMYQFGKTKVFFRNPGQLFHLEEMRER

Myosin_head Myo3.AA Myosin_head 39-634 37 7.50000000001e-245 824.5 Pfam 31-713 (765) Show / Hide
Range on Protein: 39-634
Range on HMM: 31-713/765
Sequence Identity: 37% (260 aa)

TYTGSILVAVNPYKLFDDIYNIENVRRYEGQLIGHLPPHLFAIGSGAYLRMTQTKQNQCIVISGESGAGKTESTKLIMQYLAAVNKAST--N--LITEQI
|| | ....|||||  . ||  . .  |.|.  . .|||.|||   || .| . ..||||.|.|||||||||.||..|||.|.|   .   |   ...||
TYSGHFCISVNPYKQLP-IYTQDMIQEYRGKHRYEMPPHIFAIADEAYRHMRHDRENQCIIICGESGAGKTENTKYVMQYFASVSGSNPGVNMGRVEQQI

LEANPLLEAFGNAKTTRNDNSSRFGKYIELFFN-NGLI----SGARTTEYLVEKSRVVRQTSGERNYHIFYQMLAGMSIGE-KAKYGLS--QPERYFYLN
|..||.||||||||||||.||||||||.|. |.  | |    .|.. . || ||||||.||.||||.|||||.||| |  | |....|.   |..|.|||
LQSNPILEAFGNAKTTRNNNSSRFGKYMEIHFDKTGKINPTAVGGNIENYLLEKSRVVYQTPGERNFHIFYQLLAGASQQEEKKELHLTSADPKDYHYLN

QGG---SSRL-ETRNDADDFIRTVSAMEVLNFDPNKQETAFSILAAILHIGNLS-LQNSKTQDRPDMLEVTNEGA-LSGAARLLHIDPKQLEGAILYRVT
|.|   .. .  . .||. |  |..|| ...|    |.. |.|.|||||.||.  . .   ...    .| .. . .. .. |. .||. .| ...||. 
QSGTNPCYTVDDGIDDAEEFQHTRNAMDIIGFTHEEQRSIFRIVAAILHLGNMKGFKQDQNEEQA---VVDDTEEICEIICELMGVDPEEFEKWLCYRRI

ETI----GERILTPRTLEQAEDARDGIAKSLYTSLFAWLVRSINGITNQSA-------------------------------KMTSIAILDIFGFEVF-G
.|      |.. .| . ||| .|||  || .|  .| |.|. || . .. .                               .   | .|||.|||.|  
KTGGGKRREWVTKPQNCEQAMYARDALAKAIYSRMFDWIVNRINQAICHKTQNTDDSDGQAAQWDDTVSITVVDVPDPAFDKRNYFIGVLDIYGFEIFCE

TNGFEQLCINYANEHLQFYFNKHIFQLEQLEYAKEKIEWQTISF-VDNQPVLDLLAK-RPTGILHILDDESNFPKGTEKAFVEKCHYHH-SSNS--SY-G
 |.|||.||||.|| || .|| |.|.||| || .|.|.|  | .  ||||. ||. | .| ||| .||.|..|||.|.. |..|.. .| | ..   .  
KNSFEQFCINYCNEKLQQFFNHHMFKLEQEEYVREGIQWTFIDYGFDNQPCCDLIEKKKPMGILSLLDEECWFPKATDQTFLQKLYQTHSSKHPRLHFAQ

RP-KQP------RLEFCIKHYAGRVIYQLDNVIGKNRDMLKPEVMEMFKNSRN-RVLSDMFKLLQT------------------VEQRRSMMGASGPSGM
.| ...      . .|.||||||.|.|. .. . ||.| | ....| .. |.. . ... |. ...                   . | .  | . .   
KPGRFYKRHRQGNTHFIIKHYAGDVWYNCEGWLEKNKDPLFDDLIELMWCSWDNPFMQELFPDWEWAEWAHMQIDFEADFHEEEFKRRYNRNGCQKGKQG

RKMRP-STVATRFNESLLELINNMNKC---HPFFVRCIKPNEEKAPMLFDTPIVLSQLRYSGMLE-TVRIRRNGFPIRMTFLSFMNR
.|...  ||.  | |.. .|......|   || .||||||||.|.|  || . ||.|||..|.|| ..||.| ||| |.|.  |..|
KKKWFMQTVWFQFKEQCNHLMKWLYQCAWWHPHYVRCIKPNENKQPWQFDNSMVLHQLRCNGVLEINIRICRAGFPYRWTYDEFFQR