Gene InsRL (Sea Urchin)

InsRL

Species: Sea Urchin
Alias: InsRL, SPU_003916, Spk273
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TK
Family: InsR

Sequence

Name Sequence Type Origin Length Description Download
InsRL.AA Protein None 733 None Fasta, JSON
InsRL.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of InsRL.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FN3 InsRL.AA FN3 70-122 18 0.020533 11.93 SMART 1-69 (69) Show / Hide 
Range on Protein: 70-122
Range on HMM: 1-69/69
Sequence Identity: 18% (13 aa)

PSSPATG--VNASTTSPS------RVE-----ERVIGLVESFHVTGLEHF----TEYFITLQACNS--KDCS
|..|  .  . .. ....       |.       ..| .  . ||||.      ||| ....| |.  .  .
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-IVGYR--YTVTGLKPGQYPWTEYEFRVRAVNGNDAGEG
FN3 InsRL.AA FN3 147-258 16 0.002507 18.3 SMART 1-69 (69) Show / Hide 
Range on Protein: 147-258
Range on HMM: 1-69/69
Sequence Identity: 16% (21 aa)

ADQIES---AVMINHTST-----DRVHLTWAEPSNPNGIIVIHEIRFEMMDVEVDDVGDERDAYTVVESHSTPKPVTQSTENTECVSAEGYKRVLGAELL
 .  .     .  . |||     . |.|.| .|     |.  .                                                     . . 
PGPPPNPTHLRVTDVTSTSTSDWHSVTLSWKPP-----IVGYR-----------------------------------------------------YTVT

GLKVG-----NYTAMVRAVSL--AGEG
||| |     .|.  ||||.   ||||
GLKPGQYPWTEYEFRVRAVNGNDAGEG
Kinase InsRL.AA InsR 350-624 64 2e-216 725.29 In-house 1-278 (278) Show / Hide 
Range on Protein: 350-624
Range on HMM: 1-278/278
Sequence Identity: 64% (178 aa)

LEIIRELGKGSFGMVYEGLAKGILPEEEEIS-RVAIKSVQANASMRDRIEFLNEASVMKLIDAHNVVRLLGVVSKGQPTYVIMEFMAQGDLKNWLRARRP
...|||.|.|||||||||.||||.|.||... |.|||.|..|||||.|||||||||||| ...|.|||||||.|.|||.||.||.|..||||..||.|||
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

ENQ-QDLPLIDRKSVPTLEQLLNMAAEIADGMSFLAARKYVHRDLSARNCLVSGEGTCKVADFGLARDIYQSDYYRKERGGMLPIRWMAPESVKDGVFQA
|.. ..........||.|.|...|||||.|||..|||.|.|||||..|||.|....|.|..|||..||||..|||||...||||.|||||||.|||||..
EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVFTT

SSDVWSFGILLWEMATLGELPYQGLSNEEAGEYI-KGGNVLRPPENCPEKMQEIMMACWQYQEKLRPLFGEIILNLQD
.|||||||..||||.||||.||||||||....|| ..||||||||||||..||.||.|||||.|.||.|..|| .|.|
HSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase InsRL.AA Pkinase_Tyr 350-622 44 1.3e-131 446.42 Pfam 1-270 (270) Show / Hide 
Range on Protein: 350-622
Range on HMM: 1-270/270
Sequence Identity: 44% (126 aa)

LEIIRELGKGSFGMVYEGLAKGILPEEEEISRVAIKSVQANASMRD--RIEFLNEASVMKLI-DAHNVVRLLGVVS-KGQP--TYVIMEFMAQGDLKNWL
......||.|.||.||.| .|| .|....|  ||.|..  .|. ..  | .|..||..|| . . .|.|||.||.. .|.|   |..||.|. |||.. |
ITFGKKLGEGAFGEVYKGTWKG-DPDNTKI-PVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RARRPENQQDLPLIDRKSVPTLEQLLNMAAEIADGMSFLAARKYVHRDLSARNCLVSGEGTCKVADFGLARDIYQSDYY-RKERGGMLPIRWMAPESVKD
|..|          . |  .|...||.|...||.||..|......|||| ||||||. ....|..|||||||||  ||| ||  ||.|||.|||||. ..
RKHR----------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINY

GVFQASSDVWSFGILLWEMATLGELP-YQGLSNEEAGEYI-KGGNVLRPPENCPEKMQEIMMACWQYQEKLRPLFGEIILNL
|.|   |||||||.|.||. |.|| | |.|.||||  ||| . |. . .|||||... ..|. ||.|. . || | ||.  |
GKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase InsRL.AA TyrKc 350-622 37 2.8e-119 403.46 SMART 1-280 (280) Show / Hide 
Range on Protein: 350-622
Range on HMM: 1-280/280
Sequence Identity: 37% (116 aa)

LEIIRELGKGSFGMVYEGLAKGILPEEEEISRVAIKSVQANASMRDRIEFLNEASVMKLI--DAHNVVRLLGVVSKG-------QPTYVIMEFMAQGDLK
.. ...|| | || ||.| .|           ||.|.....|    | .|..||..|. .  .  |.|||.||....       .| ...||.|. ||||
ITLGKKLGEGAFGEVYKGTWK---------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

NWLRARRPENQQDLPLIDRKSVPTLEQLLNMAAEIADGMSFLAARKYVHRDLSARNCLVSGEGTCKVADFGLARDIYQS-------DYYRKER--GGM--
. ||..||.              ....||...  ||.||..|. ....|||| ||||||. ..|.|..||||.||||         |||||    ||   
DYLRKHRPK-------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTM

LPIRWMAPESVKDGVFQASSDVWSFGILLWEMATLGELPYQG-----LSNEEAGEYIKGGNVLRPPEN--------CPEKMQEIMMACWQYQEKLRPLFG
|||||||||. ..|.|   |||||||...||. |.|. || |     .||.|. ||.| |. ...|.|        ||..| .||  ||... . || | 
LPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFS

EIILNL
||.  .
EIHECF
Kinase InsRL.AA TK 350-622 25 1e-115 389.62 In-house 1-486 (486) Show / Hide 
Range on Protein: 350-622
Range on HMM: 1-486/486
Sequence Identity: 25% (126 aa)

LEIIRELGKGSFG---MVYEGLAKGILP-------------------EEEEISRVAIKSVQ--ANASMRDRIE-----------FLNEASVMKLID----
......||.| ||   .||.|...|. |                   .|..  .||.| .   ...|......           ||.||..||. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-AHNVVRLLGVVSKG------------QPTYVIMEFMAQGD----LKNWLRARRPENQQDLPLID-----------------------------------
   |.|||.||...|            .| ...||.|. ||    |...||..||. |. .. .|                                   
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

---------------------------RKSVPTLEQLLNMAAEIADGMSFLAAR------KYVHRDLSARNCLVSGEGT-----------CKVADFG---
                           .|. .|..||| |.. ||.||..|...      ..||||| ||||||. ...           ||.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARDIYQ------------------------SDYYRKERGGMLPIRWMAPESVKDGV---------FQASSDVWSFGILLWEMATLG-ELPYQGL
     ||||||.                        .||||.. ||.|||||||||...|.|         |   |||||||.|.||. |.| | .| |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SN---------EEAGEYIKGG--------------NVLRPPENCP--------------EKMQEIMMACWQYQEKLRPLFGEIILNL
||         .|  ||.. |              . . .|..||              | ....|. ||.|. . || | ..   |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase InsRL.AA TK-Unique 350-622 38 1.1e-94 320.82 In-house 1-294 (294) Show / Hide 
Range on Protein: 350-622
Range on HMM: 1-294/294
Sequence Identity: 38% (112 aa)

LEIIRELGKGSFGMVYEGLAKGILPEEEEISRVAIKSVQANASMRDRIEFLNEASVMKLIDAH-NVVRLLGVVSKGQ-PTYVIMEFMAQGDLKNWLRARR
||. ...|.|.|| |. | ..||  .... ..||.| ...||.  |. .||.|...|| ...| |.|..||.  | . |.. |||....|.| . || .|
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

PENQQD------------LPLIDRKSVPTLEQLLNMAAEIADGMSFLAA--RKYVHRDLSARNCLVSGEGTCKVADFGLARDIYQSDYYRKERG-GMLPI
|.  |              | ..|..  ....|.. | .|| ||..||   .| |||||.|||.|... ..||..|||.|||.|    | .... |..||
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWMAPESVK--DGVF-QASSDVWSFGILLWEMATLGELPYQGLSNEEAGEYIKGGNVLRPPENC-PEKMQEIMMACWQYQEKLRPLFGEIILNL
||||||| |  .|..    |||||||.|.||..|||. || |.....  | |. |  .  ||.| .. | ..|  |||. .. || | .|.  |
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase InsRL.AA UTK 350-622 34 2.1e-89 303.3 In-house 1-296 (296) Show / Hide 
Range on Protein: 350-622
Range on HMM: 1-296/296
Sequence Identity: 34% (104 aa)

LEIIRELGKGSFGMVYEGLAKGILPEEEEISRVAIKSVQANASMRDRIE----FLNEAS---VMKLID-AHNVVRLLGVVSKGQPTYVIMEFMAQGDLKN
... |.||.| ||.|... .. . . ..| ..||.|  |. |. ..  |    |..||    .||  .   ||.||.||.....|.....|.|..||| .
VQLGRQLGQGAFGEVHKARFTQCSEHMYE-MDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRS

WLRARRPENQQDLPLIDRKSVPTLEQLLNMAAEIADGMSFLAARKYVHRDLSARNCLVSGEG-------TCKVADFG---LARDIY---------QSDYY
 ||  ||.        ..    ||.|.| ||. ||.||..|. ...||||| ||||||   .       .||.||||   ..|...         .|.||
YLRRHRPTPP------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYY

RKERGGMLPIRWMAPESVKDG-VFQASSDVWSFGILLWEMATLGELPYQGLSNEEAGEYIKGG--NVLRPPENCPEKMQEIMMACWQYQEKLRPLFGEII
..   ...||||||||.. ..  |  .|||||||...||. | | ||| |.||... . .  |    ...|. ||. . ..|..||.|    || | .. 
MAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLV

LNL
  .
QQM
Kinase InsRL.AA Musk 350-622 39 2.2e-89 295.51 In-house 1-282 (282) Show / Hide 
Range on Protein: 350-622
Range on HMM: 1-282/282
Sequence Identity: 39% (111 aa)

LEIIRELGKGSFGMVYEGLAKGILPEEEEISRVAIKSVQANASMRDRIEFLNEASVMKLIDAHNVVRLLGVVSKGQPTYVIMEFMAQGDLKNWLRARRPE
 . .|..| | || |.   | | .|.|||.. ||.|   ..||      |  ||  |   |  |.|.||||   |.|    .|.||.||| ..|... | 
IIYVRDIGEGAFGRVFQARAPGLVPYEEETM-VAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSCSPH

NQQDLPLIDR-----------KSVPTLEQLLNMAAEIADGMSFLAARKYVHRDLSARNCLVSGEGTCKVADFGLARDIYQSDYYRKERGGMLPIRWMAPE
    ..  ||               ...| |.||..|| || .|  ...|||||  ||||.  .   |.|||||.| ||  |||. .     |||||.||
RTCSRTHQDRGMRAQVSSPGPPQLKCYHQ-LCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPE

SVKDGVFQASSDVWSFGILLWEMATLGELPYQGLSNEEAGEYIKGGNVLRPPENCPEKMQEIMMACWQYQEKLRPLFGEIILNL
|. .  |   ||||..|..|||.   .. || |.. ||   ||. ||.|  ||||| |. ..|  ||| .   || | .|   .
SIWYNQFTYESDVWAYGVCLWEIFSYALQPYYGMTHEEVIYYIRQGNILSCPENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI
Kinase InsRL.AA Src 350-622 37 2.5e-87 296.42 In-house 1-255 (255) Show / Hide 
Range on Protein: 350-622
Range on HMM: 1-255/255
Sequence Identity: 37% (103 aa)

LEIIRELGKGSFGMVYEGLAKGILPEEEEISRVAIKSVQANASMRDRIEFLNEASVMKLIDAHNVVRLLGVVSKGQPTYVIMEFMAQGDLKNWLRARRPE
.  .|.||.| || |..|. .|  .       ||.|.  .   | .   || || .||  .  ..|.|. |.|.. | | . |.|..| |  .|..    
IKLCRKLGQGQFGEVWMGYWNGNTK-------VAVKTLKPGT-M-SPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK----

NQQDLPLIDRKSVPTLEQLLNMAAEIADGMSFLAARKYVHRDLSARNCLVSGEGTCKVADFGLARDIYQ--SDYYRKERGGMLPIRWMAPESVKDGVFQA
        .. .   |.||. ||| .|.||..| ...|.|||| ||| ||. .  |||||||||| . .   | |  . | ..||.|.||| .  |.|  
-------DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTI

SSDVWSFGILLWEMATLGELPYQGLSNEEAGEYIKGGNVLRPPENCPEKMQE-IMMACWQYQEKLRPLFGEIILNL
 ||||||||||.|. | |  || | .|.|. . .. |  .  |.|||... | ||. ||. . . || |  .   |
KSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase InsRL.AA ALK 350-624 39 5.7e-86 291.93 In-house 1-273 (273) Show / Hide 
Range on Protein: 350-624
Range on HMM: 1-273/273
Sequence Identity: 39% (110 aa)

LEIIRELGKGSFGMVYEGLAKGILPEEEEISRVAIKSVQANASMRDRIEFLNEASVMKLIDAHNVVRLLGVVSKGQPTYVIMEFMAQGDLKNWLRARRPE
.. .| ||.| || ||.|. .. .|       ||.|.    .|  |   |..|| .|   .  ||||..|.  . || ... |.|. ||.|  ||  ||.
ITLVRALGHGAFGEVYMGQYSH-MPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPYMIVLEYMEGGDMKSFLRECRPH

NQ--QDLPLIDRKSVPTLEQLLNMAAEIADGMSFLAARKYVHRDLSARNCLVSGEGT---CKVADFGLARDI-YQSDYYRKERGGMLPIRWMAPESVKDG
 .  |  .|       |   ||  .  .| |  .|  ....|||  ||||| . .|     |.|||| |||| |..|||||    |.|. || ||   ||
PESLQPSQL-------TMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRKGGRAMMPVKWMPPEAFMDG

VFQASSDVWSFGILLWEMATLGELPYQGLSNEEAGEYIKGGNVLRPPENCPEKMQEIMMACWQYQEKLRPLFGEIILNLQD
.|   .||||||.|.||   ||  || | .|.|  | .  |. . || |||     ||  ||| |  .|| |  |.  .|.
IFTSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRNCPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY
Kinase InsRL.AA FGFR 350-622 39 4.9e-85 288.81 In-house 1-293 (293) Show / Hide 
Range on Protein: 350-622
Range on HMM: 1-293/293
Sequence Identity: 39% (115 aa)

LEIIRELGKGSFGMVYEGLAKGILPE-EEEISRVAIKSVQANASMRDRIEFLNEASVMKLIDAH-NVVRLLGVVSKGQPTYVIMEFMAQGDLKNWLRARR
| .   || | || |  . |||| .. .|. . ||.| . .|.. .| .    |  .||.|  | |...|||. . . | ||| |. . | |. .|||||
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRARR

PEN---QQDLP-LIDRKSVPTLEQ-------------LLNMAAEIADGMSFLAARKYVHRDLSARNCLVSGEGTCKVADFGLARDIYQSDYYRKERGGML
|     ..| . ..| |  .. .|             |  .|  .| || .|| || .|||| ||| ||. .   |..|||||||| . |||||   | |
PPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNGRL

PIRWMAPESVKDGVFQASSDVWSFGILLWEMATLGELPYQGLS-NEEAGEYIKGGNVLRPPENCPEKMQEIMMACWQYQEKLRPLFGEIILNL
|| |||||.  | |.   |||||.|.||||  |.|. || .    ||  .| | |  . .|.||.. .  .|  ||  . . || | ...  |
PIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase InsRL.AA Trk 350-622 36 1.9e-83 282.73 In-house 1-275 (275) Show / Hide 
Range on Protein: 350-622
Range on HMM: 1-275/275
Sequence Identity: 36% (100 aa)

LEIIRELGKGSFGMVYEGLAKGILPEEEEISRVAIKSVQANASMRDRIEFLNEASVMKLIDAHNVVRLLGVVSKGQPTYVIMEFMAQGDLKNWLRARRPE
. ...||| | || |. .  . ..||.. .  ||.|    .||   | .|  || ..   . ...|.. ||   ..|   . |.|  |||...||.. | 
IVLKWELGEGAFGKVFLAECYNLCPEQDKM-MVAVKTLK-DASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPD

NQQDLPLID--RKSVPTLEQLLNMAAEIADGMSFLAARKYVHRDLSARNCLVSGEGTCKVADFGLARDIYQ-SDYYRKERGGMLPIRWMAPESVKDGVFQ
 .  .   .   .   |..|.|  | .|| || ..|   .||||. .||||| ..   |..|||. ||.|  .|||| .  .||||||| |||.    | 
AMCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRKFT

ASSDVWSFGILLWEMATLGELPYQGLSNEEAGEYIKGGNV-LRPPENCPEKMQEIMMACWQYQEKLRPLFGEIILNL
  |||||||. .||  | |  |. .||| |. |.|  | . |  |. ||. . .||. ||| . . | .  .|   .
YESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase InsRL.AA CTKA 350-622 35 2.1e-82 276.68 In-house 1-290 (290) Show / Hide 
Range on Protein: 350-622
Range on HMM: 1-290/290
Sequence Identity: 35% (104 aa)

LEIIRELGKGSFGMVYEGLAKGILP----EEEEISRVAIKSVQANASMRDRIEFLNEASVMK--LIDAHNVVRLLGVVSKGQPTYVIMEFMAQGDLKNWL
. |  ..| | .| |.. . ..  .           ||.|.. ..|   || .|| || |    . .  ||.|||||. . .| . |||.|  |||.  |
HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCYL

RARRPENQQDLPLIDRKSVP---------TLEQLLNMAAEIADGMSFLAARKYVHRDLSARNCLVSGEGTCKVADFGLARDIYQS-DYYRKERGGMLPIR
|| ||   |  |   |.|.|         . ||   ||..||.||..||..  ||||| .||||.    . |.||||..|       ||     ...|.|
RACRPADGQVCPARARRSIPRSFHPIEVHAHEQVY-MAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVR

WMAPESVKDGVFQASSDVWSFGILLWEMATLGELPYQGLSNEEAGEYIKGG--NVLRPPENCPEKMQEIMMACWQYQEKLRPLFGEIILNL
||||| .. | |   ||||.||.||||... ||.|. ..|  |  . . ..    | .| |||. .   |  ||.   . || |  .   |
WMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase InsRL.AA S_TKc 350-626 21 3.1e-36 127.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 350-626
Range on HMM: 1-231/231
Sequence Identity: 21% (61 aa)

LEIIRELGKGSFGMVYEGLAKGILPEEEEISRVAIKSVQANASMRDRIEFLNEASVMKLIDAHNVVRLLGVVSKGQPTYVIMEFMAQ--GDLKNWLRARR
 ||.|..|||.|| || .  |.         .|||| .         . ...| ...|  .  |.|.|..|    .  |..||.. .  |||.  .. |.
YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

PENQQDLPLIDRKSVPTLEQLLNMAAEIADGMSFLAARKYVHRDLSARNCLVSGEGTCKVADFGLARDIYQSDYYRKERGGMLPIRWMAPESVKDGVFQA
..  .        .. .  .   ....|.... ..  .. .||||   | |..   . |..|||||| .         .       .|||| .    .  
RHGLR--------FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGK

-SSDVWSFGILLWEMATLGELPYQGLSNEEAGEYIKGGNVLRPPENCPEKMQEIMMACWQYQEKLRPLFGEIIL-----NLQDYG
 ..|.||.|..|.||.. |. |..    ..  . |.           .. . .... |.|.  . ||   |.       ..  . 
CKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase InsRL.AA Pkinase 350-622 21 7e-32 113.8 Pfam 1-293 (293) Show / Hide 
Range on Protein: 350-622
Range on HMM: 1-293/293
Sequence Identity: 21% (68 aa)

LEIIRELGKGSFGMVYEGLAKGI-LPEEEEISRVAIKSVQA-NASMRDRIEFLN--EASVMKLIDAHNVVRLLGVVSKGQPTYVIMEFMAQG----DLKN
..|.| .|.|||| ||..  ||          .||.| .   ....  ... ..  |...|| ..  |.|||....  ..  |..||..  |    ||. 
YHIGRKIGSGSFGCVYKCHHKGTGK-------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFD

WLRARRPENQQDLPLIDRKSVP--TLEQLLNMAAEIADGMSFLAARKYVHRDLSARNCLVSGEGTC----KVADFGLARDI-YQSDYYRKERGGMLPIRW
....            .|. .   . ... ... .|. |. .. ... .||||   |.|.. .|..    |..|||||. . | ..   . . | .  ..
YIST------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTP--WY

MAPESVK-DGVFQASSDVWSFGILLWEMATLGELPYQGL------SNEEAGEYIKGGNVLRPPE--------------------NCPEKMQEIMMACWQY
|||| .. .     ..|.||.|..|.||.. |..|..|       .  .  . |.|. . .. .                    | .| .....  |...
MAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

QEKLRPLFGEIILN--L
  | || . .|     .
DPKKRPTAEQILQHPWF