Gene SFK7 (Sea Urchin)

SFK7

Species: Sea Urchin
Alias: SFK7, Spk290, SPU_024525
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Echino1

Sequence

Name Sequence Type Origin Length Description Download
SFK7.AA Protein None 521 None Fasta, JSON
SFK7.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of SFK7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3_1 SFK7.AA SH3_1 74-121 46 4.1e-26 90.85 Pfam 1-49 (49) Show / Hide 
Range on Protein: 74-121
Range on HMM: 1-49/49
Sequence Identity: 46% (23 aa)

IALYDYEARSEDDLSFKKGEKLEILNNTDG-DWWLARSPLTNKEGYIPS
.|||||.|...|.||||||....... .|. ||| .|.  |..||..||
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3 SFK7.AA SH3 71-128 43 8.7e-23 82.95 SMART 1-58 (58) Show / Hide 
Range on Protein: 71-128
Range on HMM: 1-58/58
Sequence Identity: 43% (25 aa)

ISFIALYDYEARSEDDLSFKKGEKLEILNNTDGDWWLARSPLTNKEGYIPSNYIAHVK
  ..|||||.|...|.||||||.....|. .|..|| .|   |..||..||||.. ..
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_2 SFK7.AA SH3_2 72-127 17 1.9e-10 39.47 Pfam 1-68 (68) Show / Hide 
Range on Protein: 72-127
Range on HMM: 1-68/68
Sequence Identity: 17% (12 aa)

SFIALYDYEA-RSEDD-----LSFKKGEKLEIL---NNTDGDWWLA-RSPLTNKE--GYIPSNYIAHV
 .... ||.. .....     |.||||......   .  ...||.. ..  ....  |..||.... .
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 SFK7.AA SH2 135-218 53 1.1e-42 127.16 Pfam 1-81 (81) Show / Hide 
Range on Protein: 135-218
Range on HMM: 1-81/81
Sequence Identity: 53% (45 aa)

WYYGKVGRKDAEKKLLAPGLQKGTFIVRDGEANPGTFSLSVRDHDPGKGEHIKHYRIRKLDNDSGYYITQRSQFQTLLELVHHY
||.||. |..||. |..|| . |||.||. | .|| ..||||| .|  |...|||||...||  ||||| | .|..| |||.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGP--GDRVKHYRIQRTDNG-GYYITGRHKFCSLQELVEHY
SH2 SFK7.AA SH2 133-224 43 7.2e-34 119.75 SMART 1-87 (87) Show / Hide 
Range on Protein: 133-224
Range on HMM: 1-87/87
Sequence Identity: 43% (41 aa)

EDWYYGKVGRKDAEKKLLAPGLQKGTFIVRDGEANPGTFSLSVRDHDPGKGEHIKHYRIRKLDNDSGYYITQ--RSQFQTLLELVHHYEQSADG
. ||.|.. |..||..|..|| . |.|.||| | ||| ..||||..     ...||||||..|. ..|||..  | .|..| |||.|| . ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-----GKVKHYRIRRNDD-GKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase SFK7.AA Src 255-506 76 7e-204 683.61 In-house 1-255 (255) Show / Hide 
Range on Protein: 255-506
Range on HMM: 1-255/255
Sequence Identity: 76% (195 aa)

LKLDAKLGSGQFGEVWKGLWNGNTEVAVKTLRPKTMTPAAFLAEANIMKTCRHENLVQLYAVCSDREPIYIVTELMKHGSLLDYLK-DGDGRHLKLPQLV
.||  |||.|||||||.|.|||||.||||||.|.|| |.|||.||.|||..|||.|||||||||. ||||||||.|.||||||||| ||.||||.||||.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DMGAQVASGMGYLERKNYVHRDLAARNVLVNTGNICKVADFGLARMIQ--DDEYCARQGAKFPIKWTSPEAALYGRFTIKSDVWSFGILLTELITYGRIP
||.||||.|| |||..||.|||||||||||...|.||||||||||.|.  |||||||.||||||||| |||..|||||||||||||||||||..||||.|
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YPGMMNMEVLEQVERGYRMPRPHNCPDSLYDMCMMKCWHKDSQQRPTFEFLHSFL
||||.|.|||.|||||||||.||||||.||...|..||||| .||||||.|..||
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase SFK7.AA SFK-Src 255-510 65 5.5e-193 577.93 In-house 1-259 (259) Show / Hide 
Range on Protein: 255-510
Range on HMM: 1-259/259
Sequence Identity: 65% (170 aa)

LKLDAKLGSGQFGEVWKGLWNGNTEVAVKTLRPKTMTPAAFLAEANIMKTCRHENLVQLYAVCSDREPIYIVTELMKHGSLLDYLKDGDGRHLKLPQLVD
 .|  ||||||||.|||| ||. ||||||||.| .|    ||.|| .||  ||.||.|||||| | |||||.||||| |||||||..  || |..|||||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

MGAQVASGMGYLERKNYVHRDLAARNVLVNTGNICKVADFGLARMI-QDDE-YCARQGAKFPIKWTSPEAALYGRFTIKSDVWSFGILLTELITYGRIPY
|.||||.|| ||| .|.||||||||||||   |.|||.|||..|.. |||| | |..||||||||| |||... || |||||||||||..|..|||||||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMMNMEVLEQVER--GYRMPRPHNCPDSLYDMCMMKCWHKDSQQRPTFEFLHSFLDDYF
||| ||||| ||.|  ||||| | |||| .| . |. || .    ||||| |   ..|.|
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKI-MFDCWQHEPDDRPTFESLKWQMEDFF
Kinase SFK7.AA Src-Echino1 255-506 74 1.7e-185 622.53 In-house 1-252 (252) Show / Hide 
Range on Protein: 255-506
Range on HMM: 1-252/252
Sequence Identity: 74% (188 aa)

LKLDAKLGSGQFGEVWKGLWNGNTEVAVKTLRPKTMTPAAFLAEANIMKTCRHENLVQLYAVCSDREPIYIVTELMKHGSLLDYLKDGDGRHLKLPQLVD
|..|.|.|.|..||||||.|||||.||||||..|||.||.||||||.||.||||..||.||||||.||||||||||..|.|.||||.|...|.|...|.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

MGAQVASGMGYLERKNYVHRDLAARNVLVNTGNICKVADFGLARMIQDDEYCARQGAKFPIKWTSPEAALYGRFTIKSDVWSFGILLTELITYGRIPYPG
|||..||||.||..||.||||||||||||..||.||.||||||||.|.|.||..||||.|||||.|||||||||||||||||||||.||..|.||.||||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYPG

MMNMEVLEQVERGYRMPRPHNCPDSLYDMCMMKCWHKDSQQRPTFEFLHSFL
|||.|||.||.||||||..|.||||||.||||||||||.||||||||||.|.
MMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase SFK7.AA SrcA 255-506 70 5.9e-174 554.5 In-house 1-250 (250) Show / Hide 
Range on Protein: 255-506
Range on HMM: 1-250/250
Sequence Identity: 70% (178 aa)

LKLDAKLGSGQFGEVWKGLWNGNTEVAVKTLRPKTMTPAAFLAEANIMKTCRHENLVQLYAVCSDREPIYIVTELMKHGSLLDYLKDGDGRHLKLPQLVD
..|  .|| |.||||| | |||.| ||.|||.| || | ||| || |||  ||. ||||||| |. |||||||| | .|||||.|||..|..||||||||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVSE-EPIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

MGAQVASGMGYLERKNYVHRDLAARNVLVNTGNICKVADFGLARMIQDDEYCARQGAKFPIKWTSPEAALYGRFTIKSDVWSFGILLTELITYGRIPYPG
| ||||.|| |.|| ||.|||| | |.||    |||.|||||||.|.|.|| |||||||||||| |||||||||||||||||||||||||.| ||.||||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG

MMNMEVLEQVERGYRMPRPHNCPDSLYDMCMMKCWHKDSQQRPTFEFLHSFL
| | ||||||||||.|| | .|| ||... |..||.|| . |||||.| |||
MNNREVLEQVERGYHMPCPQDCPESLHEL-MCQCWRKDPEERPTFEYLQSFL
Kinase SFK7.AA Src-Unclassified 255-506 56 1.1e-171 576.62 In-house 1-284 (284) Show / Hide 
Range on Protein: 255-506
Range on HMM: 1-284/284
Sequence Identity: 56% (160 aa)

LKLDAKLGSGQFGEVWKGLWNGNTEVAVKTLRPK---TMTPAAFL--------AEANIMKTCRHENLVQLYAVCSDREPIYIVTELMKHGSLLDYLKDGD
..|  ||| |||||||.| | |  .|||||.||    || |.|||        .||.||| ||| |||.||||||. ||.||.||.|  ||||..|. |.
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

GRHLKLPQL------------VDMGAQVASGMGYLERKNYVHRDLAARNVLVNTGN-----ICKVADFGLA--RMIQDDEYCARQGAKFPIKWTSPEAAL
|. | .. .            ||. ||||||| ||| | ||||||||||||. . |     . ||.|||||  . .|||.||.|.||.||.||. ||...
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

YGRFTIKSDVWSFGILLTELITYGRIPYPGMMNMEVLEQVERGYRMPRP--HNCPDSLYDMCMMKCWHKDSQQRPTFEFLHSFL
|| |.|||||||.|||| |. |.|..||||| | ||||.||||||||.|  | |||..|.  | |||||| |.||||..|  ..
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase SFK7.AA Pkinase_Tyr 255-506 51 7.29999999999e-156 528.5 Pfam 1-270 (270) Show / Hide 
Range on Protein: 255-506
Range on HMM: 1-270/270
Sequence Identity: 51% (139 aa)

LKLDAKLGSGQFGEVWKGLWN-----GNTEVAVKTLRPKTMTP----AAFLAEANIMKTC-RHENLVQLYAVCS-DREP--IYIVTELMKHGSLLDYLKD
.... |||.|.||||.|| |.     ....||||.|....| .    ..|..||.|||.  .|.|.|.||.||. ..||  ||||.|.|.||.|||||..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

G--DGRHLKLPQLVDMGAQVASGMGYLERKNYVHRDLAARNVLVNTGNICKVADFGLARMI-QDDEY-CARQGAKFPIKWTSPEAALYGRFTIKSDVWSF
   |...|....|..| .|.|.|| |||.||..||||||||.||. .|..|..|||||| |  ||.|  .|.|.|.||||..||.  ||.||.|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLTELITYGRIP-YPGMMNMEVLEQV-ERGYRMPRPHNCPDSLYDMCMMKCWHKDSQQRPTFEFLHSFL
|.|. |..|||..| |||| | ||.|.. |.|||||.|.|||| .||. |..|||.| ..||||. .|..|
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDL-MKQCWHYDPEDRPTFSEIHEQL
Kinase SFK7.AA Frk 255-510 65 9.3e-150 503.81 In-house 1-260 (260) Show / Hide 
Range on Protein: 255-510
Range on HMM: 1-260/260
Sequence Identity: 65% (171 aa)

LKLDAKLGSGQFGEVWKGLWNGNTEVAVKTLRPKTMTPAAFLAEANIMKTCRHENLVQLYAVCSDREPIYIVTELMKHGSLLDYLK--DGDGRHLKLPQL
..|  .|||||||||| |||| .| ||||||.| || |  ||.|| |||  ||  |.||||||   |||||.||||.||||..||.  .. ||.....||
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDMGAQVASGMGYLERKNYVHRDLAARNVLVNTGNICKVADFGLAR-MIQDDE--YCARQGAKFPIKWTSPEAALYGRFTIKSDVWSFGILLTELITYGR
||| ||||.|| ||| .||.|||||||||||. .||||.||||||| ...|.|  | .|.||.|||||| |||| | .||||||||||||||||.|||||
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

IPYPGMMNMEVLEQVERGYRMPRPHNCPDSLYDMCMMKCWHKDSQQRPTFEFLHSFLDDYF
.||||| | |||..|..|||||.| |||  ||.. |..|||.|...||||| |.  |.|||
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEI-MLECWHSDPMKRPTFETLQWKLEDYF
Kinase SFK7.AA SrcB 255-507 63 9.60000000001e-147 493.8 In-house 1-251 (251) Show / Hide 
Range on Protein: 255-507
Range on HMM: 1-251/251
Sequence Identity: 63% (161 aa)

LKLDAKLGSGQFGEVWKGLWNGNTEVAVKTLRPKTMTPAAFLAEANIMKTCRHENLVQLYAVCSDREPIYIVTELMKHGSLLDYLKDGDGRHLKLPQLVD
|||  |||.||||||| | .|... |||||... || | |||||||.|||  |. ||.|||| . .|||||.|| |..|.|||.||  .| .|.||.|.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVT-KEPIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

MGAQVASGMGYLERKNYVHRDLAARNVLVNTGNICKVADFGLARMIQDDEYCARQGAKFPIKWTSPEAALYGRFTIKSDVWSFGILLTELITYGRIPYPG
| ||.| || |.||.||.|||| | |.||    .||.|||||||.|.|.|| || ||||||||| |||  .| ||||||||||||||.|..|||||||||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPG

MMNMEVLEQVERGYRMPRPHNCPDSLYDMCMMKCWHKDSQQRPTFEFLHSFLD
| | ||....||||||||| |||. ||.  ||.||.. . .||||..|.| ||
MTNPEVIRNLERGYRMPRPDNCPEELYN-IMMMCWKERPEERPTFDYLQSVLD
Kinase SFK7.AA TyrKc 255-506 43 5.8e-139 468.88 SMART 1-280 (280) Show / Hide 
Range on Protein: 255-506
Range on HMM: 1-280/280
Sequence Identity: 43% (125 aa)

LKLDAKLGSGQFGEVWKGLWNGNTEVAVKTLRPKTMTPAAFLAEANIMKTC--RHENLVQLYAVCSDR-------EPIYIVTELMKHGSLLDYLKDGDGR
..|. |||.|.||||.|| |.  ..||||.|.. .   ..|. ||.||.    .|.|.|.||.||..        ||..||.|.|.||.|.|||..  ..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

HLKLPQLVDMGAQVASGMGYLERKNYVHRDLAARNVLVNTGNICKVADFGLARMIQDD--------EYCARQ--GAK--FPIKWTSPEAALYGRFTIKSD
 |....|...  |.|.|| ||..||..||||||||.||. ....|..||||.| | ||         | ...  |.|  .||.|..||.  ||.||.|||
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VWSFGILLTELITYGRIPYPG-----MMNMEVLEQVERGYRMPRPHN--------CPDSLYDMCMMKCWHKDSQQRPTFEFLHSFL
|||||... |. |||  ||||     | | ||.|.|..|||||.|.|        ||| .|.  | .||| |  .||||. .|...
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase SFK7.AA TK 255-506 27 4.6e-128 431.71 In-house 1-486 (486) Show / Hide 
Range on Protein: 255-506
Range on HMM: 1-486/486
Sequence Identity: 27% (135 aa)

LKLDAKLGSGQFG---EVWKGLWNGN--------------------------TEVAVKTLRPK-TMTPAAFLA--------------EANIMKTCR----
..|  |||.||||   ||.||.|.|                           |.||||.|... .|....|..              ||..||  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HENLVQLYAVCSDR------------EPIYIVTELMKHGS----LLDYLK--DGDGRH-----------------------------------------
 |.|.|.||.||..             ||..||.|.|.||.    |.|||.  .....|                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LKLPQLVDMGAQVASGMGYLERK------NYVHRDLAARNVLVNTGNI-----------CKVADFG---
                               | ..||. | .|.|.|| ||..|      |.|||||||||.||. .|.           ||.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARMIQDD-EYCARQ------------------------GAKFPIKWTSPEAAL---------YGRFTIKSDVWSFGILLTELITYGRIPYPGMM
     ||| |..| .|....                        |.|.||.|..||. .         ||.||.||||||||.|. |. |||. ||.|.|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

N----------MEVLEQVERG--------------YRMPRPHNCPD-------------SLYDMCMMKCWHKDSQQRPTFEFLHSFL
.           ||.|...||              .|||.| .|||              .|.  |..|||.| ..||||. ||..|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase SFK7.AA SRM 255-507 51 1.6e-126 425.35 In-house 1-253 (253) Show / Hide 
Range on Protein: 255-507
Range on HMM: 1-253/253
Sequence Identity: 51% (131 aa)

LKLDAKLGSGQFGEVWKGLWNGNTEVAVKTLRPKT-MTPAAFLAEANIMKTCRHENLVQLYAVCSDREPIYIVTELMKHGSLLDYLKDGDGRHLKLPQLV
  |  |||.| ||||| ||| |  .||.|  .    |  . . .|   ||  ||. .. |.||||  .|.||.||||. |.|. ||.| |.. |..|.|.
FTLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLL

DMGAQVASGMGYLERKNYVHRDLAARNVLVNTGNICKVADFGLARMIQDDEYCARQGAKFPIKWTSPEAALYGRFTIKSDVWSFGILLTELITYGRIPYP
|.  ||| || ||| .||.|||||||||||  .|.|||.||||||.| || |    . . |.||| |||| |. . .||||||||||| |. ||| .|||
DFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYP

GMMNMEVLEQVERGYRMPRPHNCPDSLYDMCMMKCWHKDSQQRPTFEFLHSFLD
|| | | . |..||||||.|  || . . . |..|| .| .|||.|  |   | 
GMTNHETFQQIDRGYRMPCPAECPPEVHKL-MLECWCRDPEQRPCFKDLREKLT
Kinase SFK7.AA Tec 255-508 44 2.2e-112 379.64 In-house 1-254 (254) Show / Hide 
Range on Protein: 255-508
Range on HMM: 1-254/254
Sequence Identity: 44% (115 aa)

LKLDAKLGSGQFGEVWKGLWNGNTEVAVKTLRPKTMTPAAFLAEANIMKTCRHENLVQLYAVCSDREPIYIVTELMKHGSLLDYLKDGDGRHLKLPQ--L
|..   ||||||| |  | | .. .||.|...  .|    |. || .|.   |..||||| ||| . ||||||| |.||.||.||.   . |..  .  |
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLRE-HKHHFQKNMAIL

VDMGAQVASGMGYLERKNYVHRDLAARNVLVNTGNICKVADFGLARMIQDDEYCARQGAKFPIKWTSPEAALYGRFTIKSDVWSFGILLTELITYGRIPY
 .|  .|  || ||||....|||||||| ||.  .. ||.|||..| . ||.|    |.|||.|| .||   | |.  |||||.||.|  |  . |..||
LEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPY

PGMMNMEVLEQVERGYRMPRPHNCPDSLYDMCMMKCWHKDSQQRPTFEFLHSFLDD
. | |.|| |.| .|.|. ||| |....|.  | .|||    .||||. | . . .
ENMSNSEVVEHVSQGHRLYRPHLCSMHIYQI-MYHCWHEKPEERPTFQQLLRQITE
Kinase SFK7.AA S_TKc 255-510 23 7e-58 199.53 SMART 1-231 (231) Show / Hide 
Range on Protein: 255-510
Range on HMM: 1-231/231
Sequence Identity: 23% (64 aa)

LKLDAKLGSGQFGEVWKGLWNG-NTEVAVKTLRPKTMTPAAFLAEANIMKTCRHENLVQLYAVCSDREPIYIVTELMKH--GSLLDYLKDGDGRH----L
 ..  |.|.| ||.|.|. ... . .||.| ..        .. | .|.|  .|.|.|.|| |. | . .|.|.|.. .  |.|.||.|.  ..     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

KLPQLVDMGAQVASGMGYLERKNYVHRDLAARNVLVNTGNICKVADFGLARMIQDDEYCARQGAKFPIKWTSPEAALYGRFTI-KSDVWSFGILLTELIT
   .   . .|..... |. ... .||||   |.|...    |..|||||| .                . .||      ..  |.|.||.|..| |...
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

YGRIPYPGMMNMEVLEQVERGYRMPRPHNCPDSLYDMCMMKCWHKDSQQRPTFEFLHS-----FLDDYF
 |. |.|    .......            .... |  ..||..|| ..|||   .        .. .|
-GYPPFP--QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SFK7.AA Pkinase 255-505 24 2.5e-39 140.12 Pfam 1-293 (293) Show / Hide 
Range on Protein: 255-505
Range on HMM: 1-293/293
Sequence Identity: 24% (75 aa)

LKLDAKLGSGQFGEVWKGLWNGNTE-VAVKTLRPKTMTP----AAFL-AEANIMKTCRHENLVQLYAVCSDREPIYIVTELMKHG----SLLDYLKDGDG
...  |.||| ||.|.|. . |. . ||||... ..  .    .... .|. ||| ..|.| |.|| .. |.  ||.|.|.. .|    .| ||..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RHL--KLPQLVDMGAQVASGMGYLERKNYVHRDLAARNVLVN-TGNIC---KVADFGLARMIQDDEYCARQGAKFP---IKWTSPEAAL-YGRFTIKSDV
. .     .. ..  |...|. |. ... .||||   |.|.. .|.|.   |..|||||. ..   |   . .. .   . . .||  . .   . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSFGILLTELITYGRIPYPGM----MNMEVLEQVERGYRMPRPHNCP-----------------------DSLYDMCMMKCWHKDSQQRPT-FEFLHS--
||.|..| |... || |.||       .. .. ..|  . | . ..|                       ... |  . .|..|| ..|||  . |..  
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDF-IKWCLCKDPKKRPTAEQILQHPW

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