Gene Frk (Sea Urchin)

Frk

Species: Sea Urchin
Alias: Frk, SPU_019224, Spk296, SPU_012805
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Frk

Sequence

Name Sequence Type Origin Length Description Download
Frk.AA Protein None 394 None Fasta, JSON
Frk.kin_dom Protein Kinase Domain None 167 None Fasta, JSON

Protein domain

Protein domains of Frk.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3_1 Frk.AA SH3_1 1-47 46 7.7e-19 66.47 Pfam 1-49 (49) Show / Hide 
Range on Protein: 1-47
Range on HMM: 1-49/49
Sequence Identity: 46% (23 aa)

VALFDYEARTQDDLGFKKGEELEVQNDSGD--WWLARSRLTGLEGYIPC
|||.||.|.. |.| ||||....| ..| |  || .|.  || ||..|.
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3 Frk.AA SH3 1-54 41 3.1e-16 61.18 SMART 4-58 (58) Show / Hide 
Range on Protein: 1-54
Range on HMM: 4-58/58
Sequence Identity: 41% (23 aa)

VALFDYEARTQDDLGFKKGEELEVQND-SGDWWLARSRLTGLEGYIPCNYVAKVQ
.||.||.|.. |.| ||||. ..| .. ...|| .| . || ||..|.|||....
RALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_2 Frk.AA SH3_2 1-53 22 2e-08 32.4 Pfam 3-68 (68) Show / Hide 
Range on Protein: 1-53
Range on HMM: 3-68/68
Sequence Identity: 22% (15 aa)

VALFDYEA-RTQDD-----LGFKKGEELEVQ----NDSGDWWLA-RS--RLTGLE--GYIPCNYVAKV
....||.. .  ..     | ||||. ..|.     |...||.. ..  .  | .  |..| ..|...
RVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWG--GRRMRGWFPSQWVEEC
SH2 Frk.AA SH2 61-138 51 1.7e-46 138.37 Pfam 1-81 (81) Show / Hide 
Range on Protein: 61-138
Range on HMM: 1-81/81
Sequence Identity: 51% (42 aa)

WFFGSIKRMDAEKKLLLSQNEHGSFLIRESESRVGDYSLSVRDGD---TIKHYRIRQLDEGGYFIARRCTFATLVELVQHY
|..|.| | .||. |. ..|..|.||.|||||  |||.|||||..    .|||||...|.|||.|. | .|..| |||.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
SH2 Frk.AA SH2 59-144 47 3.4e-37 130.81 SMART 1-87 (87) Show / Hide 
Range on Protein: 59-144
Range on HMM: 1-87/87
Sequence Identity: 47% (42 aa)

EPWFFGSIKRMDAEKKLLLSQNEHGSFLIRESESRVGDYSLSVRDGDTIKHYRIRQLDEGGYFIAR--RCTFATLVELVQHYQRDADG
.||..| | | .||..|.   ...|.||.|.|||  |||.||||... .||||||..|.|.|.|.   | .| .| |||.|||. ..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWKGKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase Frk.AA SFK-Src 214-380 66 6.5e-142 423.67 In-house 89-259 (259) Show / Hide 
Range on Protein: 214-380
Range on HMM: 89-259/259
Sequence Identity: 66% (114 aa)

KGHSLQLRILIDMSAQVAAGMAYLESQNYIHRDLAARNVLVGENNICKVADFGLARVI-KDEI-YESHVGAKFPIKWTAPEAANYHSFTIKSDVWSFGIL
.|.||..  |.|| ||||.|||||| ||..||||||||||||.||.|||.|||..||. .|.. |. | |||||||||||||.|.  | |||||||||||
HGRSLRMPQLVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGIL

LTEIITYGRIPYPGMTNKEVLDCVDR--GYRMPNPPGCPPELYEIMLECWKSKAMERPTFETLQWKLEEFF
..||.||||||||||||.|||  |||  ||||| ||.||.|.|.||..||. .. .|||||.|.|..|.||
MMEIVTYGRIPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase Frk.AA Src 214-376 74 2.8e-130 439.11 In-house 90-255 (255) Show / Hide 
Range on Protein: 214-376
Range on HMM: 90-255/255
Sequence Identity: 74% (124 aa)

KGHSLQLRILIDMSAQVAAGMAYLESQNYIHRDLAARNVLVGENNICKVADFGLARVIK--DEIYESHVGAKFPIKWTAPEAANYHSFTIKSDVWSFGIL
.|..|.|..||||.||||.|||||||.||||||||||||||||||.||||||||||.||  |..|... |||||||||||||.||..|||||||||||||
EGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGIL

LTEIITYGRIPYPGMTNKEVLDCVDRGYRMPNPPGCPPELYE-IMLECWKSKAMERPTFETLQWKL
||||.||||.|||||||.|||..|.||||||.|..||.|||| |||.||......|||||.|||.|
LTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase Frk.AA Frk 214-380 78 8e-124 417.66 In-house 91-260 (260) Show / Hide 
Range on Protein: 214-380
Range on HMM: 91-260/260
Sequence Identity: 78% (133 aa)

KGHSLQLRILIDMSAQVAAGMAYLESQNYIHRDLAARNVLVGENNICKVADFGLAR-VIKDEI--YESHVGAKFPIKWTAPEAANYHSFTIKSDVWSFGI
||...|...|.||.|||||||||||||||||||||||||||||.||||.||||||| ..||..  |||..||.|||||||||||||..||||||||||||
KGRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGI

LLTEIITYGRIPYPGMTNKEVLDCVDRGYRMPNPPGCPPELYEIMLECWKSKAMERPTFETLQWKLEEFF
||||||||||.|||||||.|||..||.|||||.||.||..|||||||||.|..|.||||||||||||..|
LLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase Frk.AA SrcA 214-376 66 7.2e-102 322.72 In-house 88-250 (250) Show / Hide 
Range on Protein: 214-376
Range on HMM: 88-250/250
Sequence Identity: 66% (108 aa)

KGHSLQLRILIDMSAQVAAGMAYLESQNYIHRDLAARNVLVGENNICKVADFGLARVIKDEIYESHVGAKFPIKWTAPEAANYHSFTIKSDVWSFGILLT
.|. |.|  |.||.||||.||||.|  ||||||| | |.||||| |||.|||||||.|.|. |... |||||||||||||| |  |||||||||||||||
EGKYLKLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLT

EIITYGRIPYPGMTNKEVLDCVDRGYRMPNPPGCPPELYEIMLECWKSKAMERPTFETLQWKL
|..| ||.||||| |.|||. |.|||.|| |..||  |.|.| .||.    |||||| ||  |
ELVTKGRVPYPGMNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase Frk.AA Pkinase_Tyr 215-376 53 1.4e-100 341.28 Pfam 105-270 (270) Show / Hide 
Range on Protein: 215-376
Range on HMM: 105-270/270
Sequence Identity: 53% (89 aa)

GHSLQLRILIDMSAQVAAGMAYLESQNYIHRDLAARNVLVGENNICKVADFGLARVI-KDEIY-ESHVGAKFPIKWTAPEAANYHSFTIKSDVWSFGILL
...| .  |..|..|.|.||.||||.|.|||||||||.||.|||..|..|||||| | .|. |  .. |.|.||||.|||. ||  ||.||||||||.|.
KQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLM

TEIITYGRIP-YPGMTNKEVLDCV-DRGYRMPNPPGCPPELYEIMLECWKSKAMERPTFETLQWKL
 ||.|||..| ||||.| ||.. . ..||||| |..||.|.|..|..||. .. .||||. ....|
WEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Frk.AA SRM 215-377 62 4.8e-97 325.18 In-house 91-253 (253) Show / Hide 
Range on Protein: 215-377
Range on HMM: 91-253/253
Sequence Identity: 62% (102 aa)

GHSLQLRILIDMSAQVAAGMAYLESQNYIHRDLAARNVLVGENNICKVADFGLARVIKDEIY-ESHVGAKFPIKWTAPEAANYHSFTIKSDVWSFGILLT
.  |..  |.|.  ||| ||.|||.||||||||||||||||.||.|||.|||||| ||| ||  || . . |.||||||||||  . .||||||||||| 
EKALPIPHLLDFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSH-DHNIPYKWTAPEAANYRHYSQKSDVWSFGILLH

EIITYGRIPYPGMTNKEVLDCVDRGYRMPNPPGCPPELYEIMLECWKSKAMERPTFETLQWKLE
|. ||| .||||||| | .  .||||||| |  |||| .  |||||..   .||.| .|  || 
EMFTYGQCPYPGMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase Frk.AA Src-Unclassified 215-372 51 2.3e-94 319.83 In-house 101-280 (284) Show / Hide 
Range on Protein: 215-372
Range on HMM: 101-280/284
Sequence Identity: 51% (93 aa)

GHSLQLRIL------------IDMSAQVAAGMAYLESQNYIHRDLAARNVLVGENN-----ICKVADFGLA--RVIKDEIYESHVGAKFPIKWTAPEAAN
|  | .. .            .|..|||| || ||||  |.||||||||||.|.||     . ||.|||||  ... |..|.   ||.||.||.|||.. 
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

YHSFTIKSDVWSFGILLTEIITYGRIPYPGMTNKEVLDCVDRGYRMPNP--PGCPPELYE-IMLECWKSKAMERPTFETL
|  |.|||||||.|||| || |.|..||||| |.|||  | |||||| |   .||  .|| ||. ||      ||||.||
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTL
Kinase Frk.AA SrcB 214-377 66 3.5e-94 319.0 In-house 88-251 (251) Show / Hide 
Range on Protein: 214-377
Range on HMM: 88-251/251
Sequence Identity: 66% (109 aa)

KGHSLQLRILIDMSAQVAAGMAYLESQNYIHRDLAARNVLVGENNICKVADFGLARVIKDEIYESHVGAKFPIKWTAPEAANYHSFTIKSDVWSFGILLT
.|  |.|  |||||||.| ||||.| .||||||| | |.|| |  .||.|||||||.| |. |  . ||||||||||||| |. .||||||||||||||.
EGSKLSLPKLIDMSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLM

EIITYGRIPYPGMTNKEVLDCVDRGYRMPNPPGCPPELYEIMLECWKSKAMERPTFETLQWKLE
||.|||||||||||| ||.  ..|||||| |  ||.|||.|| .|||... |||||. ||  |.
EIVTYGRIPYPGMTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase Frk.AA TK 216-376 34 3e-86 289.05 In-house 230-486 (486) Show / Hide 
Range on Protein: 216-376
Range on HMM: 230-486/486
Sequence Identity: 34% (90 aa)

HSLQLRILIDMSAQVAAGMAYLESQ------NYIHRDLAARNVLVGENNI-----------CKVADFG--------LARVI-KDEIYESHV---------
| | .. |. |..|.|.||.||.|.      |..||||||||.||||||.           ||.||||        ||| | .|. | ..          
HQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMW

---------------GAKFPIKWTAPEAANYHS---------FTIKSDVWSFGILLTEIITYGRIPYPG-MTN---------KEVLDCVDRG--------
               |.|.||.|.|||. |..          ||.||||||||.|. || |||. ||.| |.|         .||.... ||        
PFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGL

------YRMPNPPGCP--------------PELYEIMLECWKSKAMERPTFETLQWKL
      .||| ||.||              .|.|..|..||. .. .||||..|. .|
NEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Frk.AA Src-Echino1 214-376 60 6.9e-86 291.64 In-house 89-252 (252) Show / Hide 
Range on Protein: 214-376
Range on HMM: 89-252/252
Sequence Identity: 60% (99 aa)

KGHSLQLRILIDMSAQVAAGMAYLESQNYIHRDLAARNVLVGENNICKVADFGLARVIKDEIYESHVGAKFPIKWTAPEAANYHSFTIKSDVWSFGILLT
|.. ...  |||| |..|.|| ||.|.|..||||||||||||. |.||.|||||||......| .. |||.|||||||||| | .|||||||||||||.|
KCKHVKMTTLIDMGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMT

EIITYGRIPYPGMTNKEVLDCVDRGYRMPNPPGCPPELYEI-MLECWKSKAMERPTFETLQWKL
|..|.||.|||||.|.|||| |||||||| .  ||  ||.. |. ||   .  ||||| |   .
EMVTFGRYPYPGMMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase Frk.AA SFK-Abl 229-376 56 2.1e-83 272.01 In-house 104-251 (251) Show / Hide 
Range on Protein: 229-376
Range on HMM: 104-251/251
Sequence Identity: 56% (84 aa)

QVAAGMAYLESQNYIHRDLAARNVLVGENNICKVADFGLARVIKDEIYESHVGAKFPIKWTAPEAANYHSFTIKSDVWSFGILLTEIITYGRIPYPGMTN
|.| ||  || |..||||||||| |||.|   ||||||.||..   .||  .| |.||||||||.  |  |||||||||||| | || ||| .||||.  
QIADGMSFLEEQHFIHRDLAARNCLVGDNLQIKVADFGMARFVDSDFYEARIGTKMPIKWTAPESLCYDIFTIKSDVWSFGITLWEIATYGDVPYPGIHH

KEVLDCVDRGYRMPNPPGCPPELYEIMLECWKSKAMERPTFETLQWKL
..|..    ||||. | .|| |.|.||. ||     ||| |  ||  |
RDVINQLMMGYRMQRPQDCPMEIYNIMTQCWDVNPDERPSFHDLQHQL
TyrKc Frk.AA TyrKc 179-376 35 1.8e-79 271.27 SMART 1-280 (280) Show / Hide 
Range on Protein: 179-376
Range on HMM: 1-280/280
Sequence Identity: 35% (101 aa)

LQLKSLRGTGQFGEVWEGLWNNTTPVAIKTLK--------------XXX-------------------------------------------KGHS--LQ
..|.   | |.||||..| |.  ..||.|.||                                                            . |   |.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLC

LRILIDMSAQVAAGMAYLESQNYIHRDLAARNVLVGENNICKVADFGLARVIKDE--------IYESHV--GAK--FPIKWTAPEAANYHSFTIKSDVWS
.. |.... |.|.||.||.|.|.|||||||||.|||||...|..||||.| |.|.         | .    |.|  .||.|.|||. ||. ||.||||||
MKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWS

FGILLTEIITYGRIPYPG-----MTNKEVLDCVDRGYRMPNPPG--------CPPELYEIMLECWKSKAMERPTFETLQWKL
||... || |||  ||||     |.|.||. .|..||||| ||         ||.|.|.||..||. .. .||||...  ..
FGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Frk.AA SFK-Src 179-210 62 5.2e-18 49.4 In-house 1-32 (259) Show / Hide 
Range on Protein: 179-210
Range on HMM: 1-32/259
Sequence Identity: 62% (20 aa)

LQLKSLRGTGQFGEVWEGLWNNTTPVAIKTLK
 .|..  | ||||.|| | ||||| ||.||||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLK
Kinase Frk.AA Pkinase 217-370 22 3.7e-17 61.75 Pfam 102-285 (293) Show / Hide 
Range on Protein: 217-370
Range on HMM: 102-285/293
Sequence Identity: 22% (43 aa)

SL--QLRILIDMSAQVAAGMAYLESQNYIHRDLAARNVLVGENNIC----KVADFGLAR---VIKDEIYESHVGAKFPIKWTAPEAAN-YHSFTIKSDVW
..  . . ....  |.. |..|. |.. |||||   |.|. .|. .    |..|||||.     ... . . .|  .   . |||  . .   . |.|.|
CFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW---YMAPEVIRGGQYYGPKVDMW

SFGILLTEIITYGRIPYPGM----TNKEVLDCVDRGYRMPNPPGCP-----------------------PELYEIMLECWKSKAMERPTFE
|.|..| | .. || |.||     .  . . ...|  . |..  .|                       .|. ...  |.. .  .|||.|
SCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE
Kinase Frk.AA Src 179-210 59 1.5e-16 52.69 In-house 1-32 (255) Show / Hide 
Range on Protein: 179-210
Range on HMM: 1-32/255
Sequence Identity: 59% (19 aa)

LQLKSLRGTGQFGEVWEGLWNNTTPVAIKTLK
..|.   |.|||||||.|.||..|.||.||||
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLK
Kinase Frk.AA Frk 179-210 78 1.1e-14 47.02 In-house 1-32 (260) Show / Hide 
Range on Protein: 179-210
Range on HMM: 1-32/260
Sequence Identity: 78% (25 aa)

LQLKSLRGTGQFGEVWEGLWNNTTPVAIKTLK
.||    |.||||||||||||||||||.||||
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLK
Kinase Frk.AA S_TKc 179-380 20 8e-14 25.8 SMART 1-231 (231) Show / Hide 
Range on Protein: 179-380
Range on HMM: 1-231/231
Sequence Identity: 20% (53 aa)

LQLKSLRGTGQFGEVWEGLWNN-TTPVAIK--------------------------------------------TLKXXXKGHS-------LQLRILIDM
 ..  . | | ||.|. . ...    ||||                                            .|.   | .        .       .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

SAQVAAGMAYLESQNYIHRDLAARNVLVGENNICKVADFGLARVIKDEIYESHVGAKFPIKWTAPEAANYHSFTI-KSDVWSFGILLTEIITYGRIPYPG
 .|.. ...|. |.. |||||   |.|. |    |..||||||..                . |||     ...  |.|.||.|..| | .. |. |.| 
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP-

MTNKEVLDCVDRGYRMPNPPGCPPELYEIMLECWKSKAMERPTFETLQ----WKLEEFF
 . ..... .            .||. ...  |..    .||| | ||    .|. ..|
-QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase Frk.AA SrcA 179-210 62 1.6e-13 38.65 In-house 1-32 (250) Show / Hide 
Range on Protein: 179-210
Range on HMM: 1-32/250
Sequence Identity: 62% (20 aa)

LQLKSLRGTGQFGEVWEGLWNNTTPVAIKTLK
..|.   |.|.||||| | || || |||||||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLK
Kinase Frk.AA Src-Echino1 179-210 56 5e-11 33.98 In-house 1-32 (252) Show / Hide 
Range on Protein: 179-210
Range on HMM: 1-32/252
Sequence Identity: 56% (18 aa)

LQLKSLRGTGQFGEVWEGLWNNTTPVAIKTLK
|...   | |..||||.|.||  ||||.||||
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLK
Kinase Frk.AA SrcB 179-210 56 6.4e-11 33.08 In-house 1-32 (251) Show / Hide 
Range on Protein: 179-210
Range on HMM: 1-32/251
Sequence Identity: 56% (18 aa)

LQLKSLRGTGQFGEVWEGLWNNTTPVAIKTLK
|.|    |.||||||| | .|| . ||.||.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMK
Kinase Frk.AA Src-Unclassified 179-210 46 1.4e-10 32.45 In-house 1-32 (284) Show / Hide 
Range on Protein: 179-210
Range on HMM: 1-32/284
Sequence Identity: 46% (15 aa)

LQLKSLRGTGQFGEVWEGLWNNTTPVAIKTLK
..|.   | ||||||| | | .   ||.||..
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMR
Kinase Frk.AA Pkinase_Tyr 179-210 37 2.7e-09 32.09 Pfam 1-37 (270) Show / Hide 
Range on Protein: 179-210
Range on HMM: 1-37/270
Sequence Identity: 37% (14 aa)

LQLKSLRGTGQFGEVWEGLWN-----NTTPVAIKTLK
...    | |.||||..| |.     ...|||.|.||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK
Kinase Frk.AA SRM 186-210 64 3.5e-08 23.28 In-house 8-32 (253) Show / Hide 
Range on Protein: 186-210
Range on HMM: 8-32/253
Sequence Identity: 64% (16 aa)

GTGQFGEVWEGLWNNTTPVAIKTLK
| | |||||||||    .||||  |
GEGYFGEVWEGLWKGQVHVAIKVIK
Kinase Frk.AA TK 179-210 27 5.4e-08 22.08 In-house 1-61 (486) Show / Hide 
Range on Protein: 179-210
Range on HMM: 1-61/486
Sequence Identity: 27% (17 aa)

LQLKSLRGTGQFG---EVWEGLWNNT--------------------------TPVAIKTLK
..|    | ||||   ||..|.|..                           ||||.|.||
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLK
Kinase Frk.AA SFK-Abl 186-210 64 3.2e-07 19.36 In-house 8-31 (251) Show / Hide 
Range on Protein: 186-210
Range on HMM: 8-31/251
Sequence Identity: 64% (16 aa)

GTGQFGEVWEGLWNNTTPVAIKTLK
| ||.|||. | ||| . ||||| |
GEGQYGEVYKGIWNNHR-VAIKTIK
Kinase Frk.AA Pkinase 179-210 30 0.060412 7.96 Pfam 1-33 (293) Show / Hide 
Range on Protein: 179-210
Range on HMM: 1-33/293
Sequence Identity: 30% (10 aa)

LQLKSLRGTGQFGEVWEGLWNNT-TPVAIKTLK
.....  | | ||.|... . .|   ||.|..|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIK