Gene SFK5 (Sea Urchin)

SFK5

Species: Sea Urchin
Alias: SPU_026766, Spk292, SFK5
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TK
Family: Src
Subfamily: Src-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
SFK5.AA Protein None 501 None Fasta, JSON
SFK5.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of SFK5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
SH3 SFK5.AA SH3 50-106 34 2.2e-21 78.29 SMART 1-58 (58) Show / Hide 
Range on Protein: 50-106
Range on HMM: 1-58/58
Sequence Identity: 34% (20 aa)

MSYIALYAFQGRNDGDLSFEKGEVLKVFDQ-SGDWWVASSTRTNVQGYIPCNYVAPVN
. ..|||..|..|...|||.||... | .. ...|| .   ||. .|..|.|||....
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 SFK5.AA SH3_1 53-99 34 1.1e-18 65.97 Pfam 1-49 (49) Show / Hide 
Range on Protein: 53-99
Range on HMM: 1-49/49
Sequence Identity: 34% (17 aa)

IALYAFQGRNDGDLSFEKGEVLKVFDQSGD--WWVASSTRTNVQGYIPC
.|||..|......|||.||....| ..| |  || . . .|. .|..|.
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 SFK5.AA SH3_2 51-105 19 1.1e-09 36.83 Pfam 1-68 (68) Show / Hide 
Range on Protein: 51-105
Range on HMM: 1-68/68
Sequence Identity: 19% (13 aa)

SYIALYAFQG-RNDGD-----LSFEKGEVLKVF----DQSGDWWVA-SSTRTNVQ--GYIPCNYVAPV
 |...  ... .. ..     |.|.||.|.||.      ...|| .  .. ...   |..| ..|...
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 SFK5.AA SH2 113-197 36 1.4e-25 76.9 Pfam 1-81 (81) Show / Hide 
Range on Protein: 113-197
Range on HMM: 1-81/81
Sequence Identity: 36% (31 aa)

WFFGSCTRSEAIMRLQADNLPKGTFLVRESETRPGTYALTVRETDHGHPPTIKNYRVDKTKDGSELFFINPQRKFNTVIDVVKFH
|..|. .|.||  .|..   | |||||||||. || |.|.||  .   .. .| ||. .|..|   ..|   .||... . | ..
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGP--GDRVKHYRIQRTDNG--GYYITGRHKFCSLQELVEHY
SH2 SFK5.AA SH2 111-203 32 4.7e-23 83.84 SMART 1-87 (87) Show / Hide 
Range on Protein: 111-203
Range on HMM: 1-87/87
Sequence Identity: 32% (31 aa)

EEWFFGSCTRSEAIMRLQADNLPKGTFLVRESETRPGTYALTVRETDHGHPPTIKNYRVDKTKDGSELFFINP--QRKFNTVIDVVKFHTSQPGG
..|..| ..|.||   |..   | |.||||.||. || |.|.||         .|.||. ...|    ..|     |||... . | ...  |.|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-----GKVKHYRIRRNDD--GKYYIDETWRRKFPSL-ELVNHYQHNPLG
Kinase SFK5.AA Src-Unclassified 234-484 61 8.49999999999e-214 716.55 In-house 1-284 (284) Show / Hide 
Range on Protein: 234-484
Range on HMM: 1-284/284
Sequence Identity: 61% (174 aa)

LKLLDKLGQGQFGAVWKGIYDGKVEVAVKTLRAG---TMSPEAFL--------AEANLMKELKHVKLVNLYGICSDEEPIYIITELMVNGSLLGYLREGG
..||.|||.||||.||.|...|||.|||||.|.|   ||||||||        .||..||...|..||.||..||.|||.|||||.|.|||||..|||||
VHLLRKLGRGQFGEVWYGKWRGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREGG

GQYLGLREL------------VDIAAQIARGMNYLESKGYVHRDLAARNVLIGHNN-----EAKVADFGLA--KLVQDDNYVARKGAKFPVKWTAPEAAL
||||.....            ||||||.|.||.|||||.|||||||||||||||||     ..||.|||||  ||.|||||..|.||.||.||.|||...
GQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECFI

YGTFSIKSDVWSFGILLSEIATKGKTPYPGMDNQTALKEVKSGYRMPKP--MYCPDSLYD-IMTKCWNERPQQRPTFETLYNFL
||.|||||||||.||||.||.|||.||||||.|...|..|..|||||||  .||||..|. ||.|||...||.||||.|||...
YGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERGYRMPKPTNHYCPDYIYEDIMKKCWHKDPQRRPTFDTLYHYF
Kinase SFK5.AA Src 234-484 64 7.2e-185 620.45 In-house 1-255 (255) Show / Hide 
Range on Protein: 234-484
Range on HMM: 1-255/255
Sequence Identity: 64% (165 aa)

LKLLDKLGQGQFGAVWKGIYDGKVEVAVKTLRAGTMSPEAFLAEANLMKELKHVKLVNLYGICSDEEPIYIITELMVNGSLLGYLR-EGGGQYLGLRELV
.||..|||||||| ||.|...|...||||||..|||||||||.||..||.|.| |||.|| .||.||||||.||.| .|||| ||. .| |..| |..|.
IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHLHLPQLI

DIAAQIARGMNYLESKGYVHRDLAARNVLIGHNNEAKVADFGLAKLVQ--DDNYVARKGAKFPVKWTAPEAALYGTFSIKSDVWSFGILLSEIATKGKTP
|.|||.|.||.||||. |.||||||||||.|.|| .||||||||.|..  ||.|.||.|||||.|||||||..||.|.|||||||||||| || |.|..|
DMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVP

YPGMDNQTALKEVKSGYRMPKPMYCPDSLYD-IMTKCWNERPQQRPTFETLYNFL
||||.|. .|..|. |||||.|. |||.||. ||..||...|.||||||.|..||
YPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase SFK5.AA SFK-Src 234-488 58 7.70000000001e-166 495.94 In-house 1-259 (259) Show / Hide 
Range on Protein: 234-488
Range on HMM: 1-259/259
Sequence Identity: 58% (151 aa)

LKLLDKLGQGQFGAVWKGIYDGKVEVAVKTLRAGTMSPEAFLAEANLMKELKHVKLVNLYGICSDEEPIYIITELMVNGSLLGYLREGGGQYLGLRELVD
 .|  |||.|||| ||||   .. |||||||. |.|| | ||.|| .|| |.| .|. || .| | |||||||||| .|||| ||.|  |. | .  |||
IRLEKKLGSGQFGDVWKGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSLRMPQLVD

IAAQIARGMNYLESKGYVHRDLAARNVLIGHNNEAKVADFGLAKLV-QDDN-YVARKGAKFPVKWTAPEAALYGTFSIKSDVWSFGILLSEIATKGKTPY
 |||.| || ||| . .|||||||||||.| ||  ||.|||..  . |||  | |..|||||.|||||||... .|||||||||||||. || | |  ||
MAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGRIPY

PGMDNQTALKEVKS--GYRMPKPMYCPDSLYDIMTKCWNERPQQRPTFETLYNFLDDYF
||| |.  |. |    |||||.|  ||| .| ||  || ..|  |||||.|   ..|.|
PGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQHEPDDRPTFESLKWQMEDFF
Kinase SFK5.AA Pkinase_Tyr 234-484 47 1.3e-146 497.15 Pfam 1-270 (270) Show / Hide 
Range on Protein: 234-484
Range on HMM: 1-270/270
Sequence Identity: 47% (127 aa)

LKLLDKLGQGQFGAVWKGIYD-----GKVEVAVKTLRAGTMSP----EAFLAEANLMKEL-KHVKLVNLYGICS-DEEP--IYIITELMVNGSLLGYLRE
.... |||.|.|| |.||...     .|..||||.|. |.|..    |.|..||..||.| .| ..|.|||.|. ..||  |||..|.| .|.|| |||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

G--GGQYLGLRELVDIAAQIARGMNYLESKGYVHRDLAARNVLIGHNNEAKVADFGLAKLV-QDDNY-VARKGAKFPVKWTAPEAALYGTFSIKSDVWSF
   ..| | . .|.....|||.||.|||||...||||||||.|...|| .|..|||||...  ||.| ..|.|.|.|.||.|||.  || |..|||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GILLSEIATKGKTP-YPGMDNQTALKEV-KSGYRMPKPMYCPDSLYDIMTKCWNERPQQRPTFETLYNFL
|.|. || | |..| ||||.|.  .. . ..|||||.|..||| .||.|..||.. |..||||. ....|
GVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase SFK5.AA SrcA 234-484 59 1.3e-142 453.7 In-house 1-250 (250) Show / Hide 
Range on Protein: 234-484
Range on HMM: 1-250/250
Sequence Identity: 59% (150 aa)

LKLLDKLGQGQFGAVWKGIYDGKVEVAVKTLRAGTMSPEAFLAEANLMKELKHVKLVNLYGICSDEEPIYIITELMVNGSLLGYLREGGGQYLGLRELVD
..|  .||||.|| || | . |.  ||.|||. ||||||||| || .|| |.| |||.|| . | ||||||.|| |  |||| .|... |.|| | .|||
IRLERRLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMSPEAFLEEAQIMKKLRHDKLVQLYAVVS-EEPIYIVTEYMCKGSLLDFLKDEEGKYLKLPQLVD

IAAQIARGMNYLESKGYVHRDLAARNVLIGHNNEAKVADFGLAKLVQDDNYVARKGAKFPVKWTAPEAALYGTFSIKSDVWSFGILLSEIATKGKTPYPG
.|||.| || |.|   |.|||| | |.|.| |   |.||||||.|..|. | ||.|||||.||||||||||| | |||||||||||| |. |||. ||||
MAAQVAEGMAYMERMNYIHRDLRAANILVGENLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPG

MDNQTALKEVKSGYRMPKPMYCPDSLYDIMTKCWNERPQQRPTFETLYNFL
| |   |  |  ||.|| |  || ||...| .||   |. ||||| |  ||
MNNREVLEQVERGYHMPCPQDCPESLHELMCQCWRKDPEERPTFEYLQSFL
Kinase SFK5.AA TyrKc 234-484 41 1.3e-140 474.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 234-484
Range on HMM: 1-280/280
Sequence Identity: 41% (118 aa)

LKLLDKLGQGQFGAVWKGIYDGKVEVAVKTLRAGTMSPEAFLAEANLMKEL--KHVKLVNLYGICSDE-------EPIYIITELMVNGSLLGYLREGGGQ
..|..||| |.|| |.||...  ..||||.|....   |.|. ||..|..|  .|  .|.|||.|...       ||..|..|.| .|.|. |||. ...
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

YLGLRELVDIAAQIARGMNYLESKGYVHRDLAARNVLIGHNNEAKVADFGLAKLVQDD--------NYVARK--GAK--FPVKWTAPEAALYGTFSIKSD
 | ...|.... |||.||.||.||...||||||||.|.|.|. .|..||||.. . ||         |....  |.|  .|..|.|||.  ||.|..|||
-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSD

VWSFGILLSEIATKGKTPYPG-----MDNQTALKEVKSGYRMPKPMY--------CPDSLYDIMTKCWNERPQQRPTFETLYNFL
|||||... || | |..||||     |.|| ... ||.|||||.| .        ||| .|.||..||.| | .||||.... ..
VWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase SFK5.AA Src-Echino1 234-484 58 3.7e-135 455.31 In-house 1-252 (252) Show / Hide 
Range on Protein: 234-484
Range on HMM: 1-252/252
Sequence Identity: 58% (147 aa)

LKLLDKLGQGQFGAVWKGIYDGKVEVAVKTLRAGTMSPEAFLAEANLMKELKHVKLVNLYGICSDEEPIYIITELMVNGSLLGYLREGGGQYLGLRELVD
|..  |.|.|..| ||||...|  .||||||. .|||| .||||||.||...|  .| .| .|||.|||||.|||| ||.|. ||..| .. . . .|.|
LRMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

IAAQIARGMNYLESKGYVHRDLAARNVLIGHNNEAKVADFGLAKLVQDDNYVARKGAKFPVKWTAPEAALYGTFSIKSDVWSFGILLSEIATKGKTPYPG
. |.|| ||.||.|| .|||||||||||.|. |  |.||||||...|.| |....|||.|.||||||||||| | |||||||||||. |. | |. ||||
MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYPG

MDNQTALKEVKSGYRMPKPMYCPDSLYDI-MTKCWNERPQQRPTFETLYNFL
| |.  |..|. ||||||.  ||||||.. | |||   |||||||| |..|.
MMNREVLDQVDRGYRMPKMHHCPDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase SFK5.AA Frk 234-488 58 9.1e-134 450.69 In-house 1-260 (260) Show / Hide 
Range on Protein: 234-488
Range on HMM: 1-260/260
Sequence Identity: 58% (151 aa)

LKLLDKLGQGQFGAVWKGIYDGKVEVAVKTLRAGTMSPEAFLAEANLMKELKHVKLVNLYGICSDEEPIYIITELMVNGSLLGYLR--EGGGQYLGLREL
..|. .|| |||| || | .. .. ||||||..||| |. ||.|| .||.|.| ||..|| .|  ||||||||||| .|||. ||.  .. |. . ...|
IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQL

VDIAAQIARGMNYLESKGYVHRDLAARNVLIGHNNEAKVADFGLAK-LVQDDN--YVARKGAKFPVKWTAPEAALYGTFSIKSDVWSFGILLSEIATKGK
||.|||.| || ||||. |.||||||||||.| .|  |.||||||. |..|.   | .| ||.||.|||||||| |  |.|||||||||||| || | |.
VDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGR

TPYPGMDNQTALKEVKSGYRMPKPMYCPDSLYDIMTKCWNERPQQRPTFETLYNFLDDYF
 ||||| |.  |. |. |||||.|  ||  ||.|| .||.. |..|||||||   |.|||
MPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase SFK5.AA SrcB 234-485 57 3.3e-128 432.21 In-house 1-251 (251) Show / Hide 
Range on Protein: 234-485
Range on HMM: 1-251/251
Sequence Identity: 57% (145 aa)

LKLLDKLGQGQFGAVWKGIYDGKVEVAVKTLRAGTMSPEAFLAEANLMKELKHVKLVNLYGICSDEEPIYIITELMVNGSLLGYLREGGGQYLGLRELVD
|||  ||| |||| || | |.... |||||.. |||||||||||||.||.|.| .|| || . . | ||||||| | .|.|| .|.   |  | |  |.|
LKLVKKLGAGQFGEVWMGYYNNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKLSLPKLID

IAAQIARGMNYLESKGYVHRDLAARNVLIGHNNEAKVADFGLAKLVQDDNYVARKGAKFPVKWTAPEAALYGTFSIKSDVWSFGILLSEIATKGKTPYPG
..|||| || |.| . |.|||| | |.|. .    |.||||||....|. | || |||||.|||||||  .|.| |||||||||||| || | |. ||||
MSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPYPG

MDNQTALKEVKSGYRMPKPMYCPDSLYDIMTKCWNERPQQRPTFETLYNFLD
| |   .. .. |||||.|  ||. ||.||..|| ||| .||||. |   ||
MTNPEVIRNLERGYRMPRPDNCPEELYNIMMMCWKERPEERPTFDYLQSVLD
Kinase SFK5.AA TK 234-484 25 7.1e-123 414.01 In-house 1-486 (486) Show / Hide 
Range on Protein: 234-484
Range on HMM: 1-486/486
Sequence Identity: 25% (124 aa)

LKLLDKLGQGQFG---AVWKGIYDGK--------------------------VEVAVKTLRAG-TMSPEAFLA--------------EANLMKELK----
..|..|||.||||    |.||.. |.                          ..||||.|..| .||.|.|..              ||. || ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HVKLVNLYGICSDE------------EPIYIITELMVNGS----LLGYLR--EGGGQY-----------------------------------------
 |  .|.|||.|...            ||..|..|.| .|.    |. |||   ...|                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LGLRELVDIAAQIARGMNYLESK------GYVHRDLAARNVLIGHNNE-----------AKVADFG---
                               | ...|. ...|||.|| ||.||      ..|||||||||.|.|.||            .|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAKLVQDD-NYVARK------------------------GAKFPVKWTAPEAAL---------YGTFSIKSDVWSFGILLSEIATKGKTPYPG-M
     ||. ...| .|....                        |.|.|..|.|||. .         ||.|..||||||||.|. || | |..||.| |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DN---------QTALKEVKSG--------------YRMPKPMYCP--------------DSLYDIMTKCWNERPQQRPTFETLYNFL
.|         |  .. ...|              .|||.|..||              . .||.|..||.. |..||||..|...|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase SFK5.AA SRM 234-485 48 1.9e-117 394.45 In-house 1-253 (253) Show / Hide 
Range on Protein: 234-485
Range on HMM: 1-253/253
Sequence Identity: 48% (122 aa)

LKLLDKLGQGQFGAVWKGIYDGKVEVAVKTLRAGT-MSPEAFLAEANLMKELKHVKLVNLYGICSDEEPIYIITELMVNGSLLGYLREGGGQYLGLRELV
  |  |||.| || || |   |.|.||.|  .    |  . . .|   ||.| | ... |. .||  .|.|||||||  |.|. |||.  .. | . .|.
FTLCRKLGEGYFGEVWEGLWKGQVHVAIKVIKRDNLMHQHMLQKEIQAMKKLRHKHIIRLHAVCSVGDPVYIITELMRKGNLQQYLRDSDEKALPIPHLL

DIAAQIARGMNYLESKGYVHRDLAARNVLIGHNNEAKVADFGLAKLVQDDNYVARKGAKFPVKWTAPEAALYGTFSIKSDVWSFGILLSEIATKGKTPYP
|.| |.| || |||.. |.||||||||||.| ||  ||.||||| |. || |    . . |.|||||||| |. .|.||||||||||| |. |.|  |||
DFACQVAEGMCYLEEQNYIHRDLAARNVLVGDNNLCKVGDFGLARLIKDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGILLHEMFTYGQCPYP

GMDNQTALKEVKSGYRMPKPMYCPDSLYDIMTKCWNERPQQRPTFETLYNFLD
|| |  ..  .. ||||| |. || . .  | .||   |.|||.| .|   | 
GMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT
Kinase SFK5.AA Tec 234-486 44 9.3e-115 387.55 In-house 1-254 (254) Show / Hide 
Range on Protein: 234-486
Range on HMM: 1-254/254
Sequence Identity: 44% (112 aa)

LKLLDKLGQGQFGAVWKGIYDGKVEVAVKTLRAGTMSPEAFLAEANLMKELKHVKLVNLYGICSDEEPIYIITELMVNGSLLGYLREGGGQYLGLR-ELV
|...  ||.|||| |  | . .. .||.|... |.|| | |. ||  |..| | ||| |||.|| . ||||.|| | .|.|| |||| ...  .    | 
LTFMKELGSGQFGVVHLGKWRHQYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAILL

DIAAQIARGMNYLESKGYVHRDLAARNVLIGHNNEAKVADFGLAKLVQDDNYVARKGAKFPVKWTAPEAALYGTFSIKSDVWSFGILLSEIATKGKTPYP
..  ..  || |||.....|||||||| |.| ..  ||.|||..  | || |.   |.|||||| .||   |  .| |||||.||.|  |. . || ||.
EMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYE

GMDNQTALKEVKSGYRMPKPMYCPDSLYDIMTKCWNERPQQRPTFETLYNFLDD
 |.|    ..|  |.|. .|  |....|.|| .|| |.| .||||. |   . .
NMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE
Kinase SFK5.AA S_TKc 234-488 24 1.5e-58 201.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 234-488
Range on HMM: 1-231/231
Sequence Identity: 24% (65 aa)

LKLLDKLGQGQFGAVWKGIYDG-KVEVAVKTLRAGTMSPEAFLAEANLMKELKHVKLVNLYGICSDEEPIYIITELMVN--GSLLGYLREGGG----QYL
 ..|.|.|.| || |.|..  . . .||.| ..      | .. | ...|. .|  .|.||... | . .|...|.. .  |.|. |... |.    ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

GLRELVDIAAQIARGMNYLESKGYVHRDLAARNVLIGHNNEAKVADFGLAKLVQDDNYVARKGAKFPVKWTAPEAALYGTFSI-KSDVWSFGILLSEIAT
   .   ...||.....|. |.| .||||   |.|. .  . |..|||||...        .       . |||      ..  |.|.||.|..| | ..
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

KGKTPYPGMDNQTALKEVKSGYRMPKPMYCPDSLYDIMTKCWNERPQQRPTFETLYN-----FLDDYF
 |..|.|  . |. .| ..           .... |.. ||..  |..|||   . .      .. .|
-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SFK5.AA Pkinase 234-484 25 6.3e-47 167.01 Pfam 1-293 (293) Show / Hide 
Range on Protein: 234-484
Range on HMM: 1-293/293
Sequence Identity: 25% (77 aa)

LKLLDKLGQGQFGAVWKGIYDGKVE-VAVKTLRAGTMSPEAF-----LAEANLMKELKHVKLVNLYGICSDEEPIYIITELMVNG----SLLGYLR--EG
.... |.|.| || |.|..  |  . ||||...  . ...       |.|. .||.|.|   | ||... |.  ||...|.. .|    .|  |..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GGQYLGLRELVDIAAQIARGMNYLESKGYVHRDLAARNVLIGHNNEA----KVADFGLAKLVQDDNYVARKGAKFPV---KWTAPEAAL-YGTFSIKSDV
|. |.  .|. ... ||.||..|. |.| .||||   |.|| .|..     |..||||||...   |     .. ..    . |||  . .   . |.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WSFGILLSEIATKGKTPYPGM----DNQTALKEVKSGYRMPKPMYCP-----------------------DSLYDIMTKCWNERPQQRPTFETLYNF--L
||.|..| | .. |..|.||     .  . .. ..   . | .  .|                       ... |....|..  |..|||.| . .   .
WSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF