Gene TEC (Sea Urchin)

TEC

Species: Sea Urchin
Alias: SPU_012277, TEC, Spk300, SPU_012278
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TK
Family: Tec

Sequence

Name Sequence Type Origin Length Description Download
TEC.AA Protein None 828 None Fasta, JSON
TEC.kin_dom Protein Kinase Domain None 236 None Fasta, JSON

Protein domain

Protein domains of TEC.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
BTK TEC.AA BTK 286-321 35 7.7e-05 14.97 SMART 1-37 (37) Show / Hide 
Range on Protein: 286-321
Range on HMM: 1-37/37
Sequence Identity: 35% (13 aa)

NSNLSDRYHYGIWTT-KWTCCQKDYKGAPGCQNTFRQ
|...   || . |.  .| |||   |.||||.     
NNHRMQKYHPCFWMDGHWLCCQQTCKNAPGCCPCHPH
SH3 TEC.AA SH3 368-424 41 1.7e-16 62.05 SMART 1-58 (58) Show / Hide 
Range on Protein: 368-424
Range on HMM: 1-58/58
Sequence Identity: 41% (24 aa)

MIVIAKYDYDPLETIDIPLKRGKEYSVLNNSRDYWWKVRDR-HGREGFIPSNYVEEKS
. |.|.|||.. .  ....|.|  . ||. . | |||.| .  |.||..|||||||. 
PYVRALYDYQAQNPDELSFKKGDIITVLEKDDDGWWKGRCNRTGQEGWFPSNYVEEID
SH3_1 TEC.AA SH3_1 371-417 36 7.6e-13 46.35 Pfam 1-49 (49) Show / Hide 
Range on Protein: 371-417
Range on HMM: 1-49/49
Sequence Identity: 36% (18 aa)

IAKYDYDPLETIDIPLKRGKEYSVLNNSRD-YWWKVRDRH-GREGFIPS
.|.|||.. .  ....|.| .. |.. | |  |||.|.   |.||..||
VALYDYQAQQPDELSFKKGDIIHVIEKSDDWDWWKGRCNNTGQEGWFPS
SH3_2 TEC.AA SH3_2 369-423 25 6e-06 23.65 Pfam 1-68 (68) Show / Hide 
Range on Protein: 369-423
Range on HMM: 1-68/68
Sequence Identity: 25% (17 aa)

IVIAKYDYDP-LETID-----IPLKRGKEYSVL---NNSRDYWWKV-RD-RHGRE--GFIPSNYVEEK
 ...  ||.|   . .     . .|.|    |.   . ..| ||.. .   .||.  |..||..||| 
YYRVHCDYVPATYCNENHEPQLHFKKGDVIKVIDNGDKDWDNWWWCWETIWGGRRMRGWFPSQWVEEC
SH2 TEC.AA SH2 433-523 33 7.2e-22 79.89 SMART 1-87 (87) Show / Hide 
Range on Protein: 433-523
Range on HMM: 1-87/87
Sequence Identity: 33% (32 aa)

YDWFNGTWSRQRTELELKQE-SKEGCFTVRNSRT-PGLCTLSVLAKEKGPSGEDVVRHYHIKQNSIKEFYVAE--KHCFRDMGKLVEYHQHNAGG
. |. |  ||.  |  ||..  ..|.| || |.. ||  .|||  |       . |.||.|..|  . .|..|  ...| .   ||...|||..|
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK-------GKVKHYRIRRNDDGKYYIDETWRRKFPSL-ELVNHYQHNPLG
SH2 TEC.AA SH2 435-517 35 2.1e-20 61.76 Pfam 1-81 (81) Show / Hide 
Range on Protein: 435-517
Range on HMM: 1-81/81
Sequence Identity: 35% (30 aa)

WFNGTWSRQRTELELKQ-ESKEGCFTVRNSR-TPGLCTLSVLAKEKGPSGEDVVRHYHIKQNSIKEFYVAEKHCFRDMGKLVEYH
|. |  |||  |  |.. . ..| | || |. |||  ||||. . .    .|.|.||.|...  . .|....|.|..   |||..
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLSVRDDGP----GDRVKHYRIQRTDNGGYYITGRHKFCSLQELVEHY
Kinase TEC.AA Tec 554-791 64 8.49999999999e-188 630.18 In-house 1-237 (254) Show / Hide 
Range on Protein: 554-791
Range on HMM: 1-237/254
Sequence Identity: 64% (154 aa)

LKILQELGRGQFGIVHLAKLTHNNRFVAVKRMQEGSMSEEDFIDEAKVMKELQHENLVQLYGVTSAQRPMCIVTEYMSKGCLLSYLRTHKFMLLENTAIL
|....|||.||||.|||.|..| ...||.|...||||||||||.|||||..|.|..|||||||.|.|||..||||||..||||.|||.||... .|.|||
LTFMKELGSGQFGVVHLGKWRH-QYDVAIKMIKEGSMSEEDFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHKHHFQKNMAIL

IYMTQQVCFGMAYLESKGFIHRDLAARNCLVGDKHIVKVADFGLTRYVMDDEYTSSG-TKFPIKWAPPEVLHYTRFSSKSDVWAFGILMWEVFSGGLAPY
..|.|.||.||||||...|||||||||||||||...|||.|||.||||.||.||||. ||||.||.||||.||.|.||||||||||.|||||||.|..||
LEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVGTKFPVKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPY

PAMSNVEVVDQVTRHNYRMERPDHCPYQMYRIMKDCWRE
..|||.|||..|... .|..||..|....|.||..||.|
ENMSNSEVVEHVSQG-HRLYRPHLCSMHIYQIMYHCWHE
Kinase TEC.AA Pkinase_Tyr 554-791 46 3.8e-125 424.46 Pfam 1-255 (270) Show / Hide 
Range on Protein: 554-791
Range on HMM: 1-255/270
Sequence Identity: 46% (118 aa)

LKILQELGRGQFGIVHLAKLT----HNNRFVAVKRMQEGSMSE----EDFIDEAKVMKEL-QHENLVQLYGVTS-AQRP--MCIVTEYMSKGCLLSYLRT
......||.|.|| |......     ..  |||| . ||.|.|    |||. |||.||.| .|.|.|.|||| .  ..|  ..||.||| .|.||.|||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

H--KFMLLENTAILIYMTQQVCFGMAYLESKGFIHRDLAARNCLVGDKHIVKVADFGLTRYV-MDDEY--TSSGTKFPIKWAPPEVLHYTRFSSKSDVWA
|      |     |. | .|.. ||.|||||..||||||||||||.....||..||||.|..  ||.|  ...|.|.|||| .||...| .|..|||||.
HREDKQPLTMKD-LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FGILMWEVFSGGLAP-YPAMSNVEVVDQVTRHNYRMERPDHCPYQMYRIMKDCWRE
||.||||.|. |  | || ||| ||........|||..|..||  .|..||.||..
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHY
Kinase TEC.AA TyrKc 554-796 39 2.8e-114 386.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 554-796
Range on HMM: 1-280/280
Sequence Identity: 39% (114 aa)

LKILQELGRGQFGIVHLAKLTHNNRFVAVKRMQEGSMSEEDFIDEAKVMKEL--QHENLVQLYGVTSAQ-------RPMCIVTEYMSKGCLLSYLRTHK-
.. ...||.|.||.|......   . |||| ..|..  .|||..||..|..|  .|.|.|.|||| . |        |..||.|||..|.|..||| |. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

FMLLENTAILIYMTQQVCFGMAYLESKGFIHRDLAARNCLVGDKHIVKVADFGLTRYVMDD-------EYTSS----GTK--FPIKWAPPEVLHYTRFSS
     ... |...  |.. ||.||.||..|||||||||||||..|.||..||||.|.. ||       .| ..    |.|  .||.| .||.. | .|..
K---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KSDVWAFGILMWEVFSGGLAPYPA-----MSNVEVVDQVTRHNYRMERPDH--------CPYQMYRIMKDCWRE----------CAKVY
|||||.||..|||.|. |  |||      ||| ||. .| .. |||..|..        ||  ||.|||.||.|          . .  
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV-KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase TEC.AA Src 554-791 51 9.80000000001e-111 374.19 In-house 1-240 (255) Show / Hide 
Range on Protein: 554-791
Range on HMM: 1-240/255
Sequence Identity: 51% (126 aa)

LKILQELGRGQFGIVHLAKLTHNNRFVAVKRMQEGSMSEEDFIDEAKVMKELQHENLVQLYGVTSAQRPMCIVTEYMSKGCLLSYLR-THKFMLLENTAI
.| ...||.|||| |  ..   .|  |||| . .|.|| |.|  ||..||.|.||.||||| | |   |  |||||||.|.|| ||. . .   | .  .
IKLCRKLGQGQFGEVWMGYW-NGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKKDGEGRHL-HLPQ

LIYMTQQVCFGMAYLESKGFIHRDLAARNCLVGDKHIVKVADFGLTRYVM--DDEY-TSSGTKFPIKWAPPEVLHYTRFSSKSDVWAFGILMWEVFSGGL
||.|. ||  |||||||. .||||||||| |||.. ..||||||| | ..  ||||  ..| ||||||  || ..| ||. ||||| ||||..|... | 
LIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGR

APYPAMSNVEVVDQVTRHNYRMERPDHCPYQMYR-IMKDCWRE
 ||| |.| ||..|| | .||| .|..|| ..|  ||. ||..
VPYPGMTNHEVLQQVER-GYRMPCPHNCPDELYEQIMLQCWHK
Kinase TEC.AA SFK-Src 554-791 48 1.1e-109 326.34 In-house 1-240 (259) Show / Hide 
Range on Protein: 554-791
Range on HMM: 1-240/259
Sequence Identity: 48% (119 aa)

LKILQELGRGQFGIVHLAKLTHNNRF-VAVKRMQEGSMSEEDFIDEAKVMKELQHENLVQLYGVTSAQRPMCIVTEYMSKGCLLSYLRTHKFMLLENTAI
 .  . || |||| |   | . ||   |||| .  |.||.| |  || ||| |.|.||.||| |     |. |.|| |  | || ||.  .   | .   
IRLEKKLGSGQFGDVW--KGRWNNTTEVAVKTLKPGAMSAEEFLQEAQVMKKLRHPNLIQLYAVCTDGEPIYIITELMKYGSLLDYLHEPHGRSL-RMPQ

LIYMTQQVCFGMAYLESKGFIHRDLAARNCLVGDKHIVKVADFGLTRYVMDDEY---TSSGTKFPIKWAPPEVLHYTRFSSKSDVWAFGILMWEVFSGGL
|. |. ||  |||||| . |.|||||||| ||||  ..||.|||. | . .|.       | ||||||  ||   . ||| |||||.||||| |.   | 
LVDMAAQVAHGMAYLEAQNFVHRDLAARNVLVGDNNVCKVGDFGMSRVLAQDDEGYTAHEGAKFPIKWTAPEAMNMNRFSIKSDVWSFGILMMEIVTYGR

APYPAMSNVEVVDQVTR-HNYRMERPDHCPYQMYRIMKDCWRE
 ||| |.| ||. || |   |||. |  || ..| || |||..
IPYPGMTNMEVLQQVDRPEGYRMPCPPNCPDEYYKIMFDCWQH
Kinase TEC.AA TK 554-791 24 5.5e-107 359.8 In-house 1-471 (486) Show / Hide 
Range on Protein: 554-791
Range on HMM: 1-471/486
Sequence Identity: 24% (116 aa)

LKILQELGRGQFG---IVHLAKLTHNN-------------------------RFVAVKRMQEG-SMSEEDFID--------------EAKVMKELQ----
......||.||||    |.....   |                           |||| . || .||.|.|.|              || .|| ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HENLVQLYGVTSAQ------------RPMCIVTEYMSKGC----LLSYLRTHK----------------------------------------------
 |.|.|.|||| . .            .|..||.|||..|.    |..|||...                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------FMLLE-------------NTAILIYMTQQVCFGMAYLESK------GFIHRDLAARNCLVGDKHI-----------VKVADFG---
                ||              ... |. | .|.. ||.||.||      .|.||||||||||||....           .|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LTRYVMD--DEYTSS------------------------GTKFPIKWAPPEVLH---------YTRFSSKSDVWAFGILMWEVFSGGLAPYPA-M
     |.|.. .  | |..|                        |.|.||.| .||.|          | .|..|||||.||.||||.|. | .||.  |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SN---------VEVVDQVTR-------------HNYRMERPDHCP--------------YQMYRIMKDCWRE
||          ||.....|             . .||..|.|||                .|..|..||..
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHY
Kinase TEC.AA Abl 554-790 49 2e-100 335.77 In-house 1-236 (252) Show / Hide 
Range on Protein: 554-790
Range on HMM: 1-236/252
Sequence Identity: 49% (118 aa)

LKILQELGRGQFGIVHLAKLTHNNRFVAVKRMQEGSMSEEDFIDEAKVMKELQHENLVQLYGVTSAQRPMCIVTEYMSKGCLLSYLRTHKFMLLENTAIL
. . . || ||.| |  .   . .  |||| ..| .|  ..|. || .|||..|.||||| ||     |  |.||.|..| || |||  .  .|.   .|
IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDREELP-AVVL

IYMTQQVCFGMAYLESKGFIHRDLAARNCLVGDKHIVKVADFGLTRYVMDDEYTS-SGTKFPIKWAPPEVLHYTRFSSKSDVWAFGILMWEVFSGGLAPY
.||  |. .|| |||.. ||||||||||||||..||||||||||.| . || ||   | ||||||  || | | .|||||||||||.|.||.   |..||
LYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARMMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPY

PAMSNVEVVDQVTRHNYRMERPDHCPYQMYRIMKDCWR
|..   .| ... . .||||||. || ..|..|. ||.
PGIDLSHVYHKLEK-GYRMERPEGCPPKVYELMRQCWQ
Kinase TEC.AA UTK 554-790 37 7.3e-99 334.75 In-house 1-280 (296) Show / Hide 
Range on Protein: 554-790
Range on HMM: 1-280/296
Sequence Identity: 37% (105 aa)

LKILQELGRGQFGIVHLAKLTHNN-----RFVAVKRMQEGSM---SEE---DFIDEAK---VMKELQ-HENLVQLYGVTSAQRPMCIVTEYMSKGCLLSY
......||.|.||.||.|..|. .       ||||  |....   ..|   ||. ||.   .|| .. |.|...|.|| ... |..||||||..| |.||
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRTHKFMLL-----ENTAILIYMTQQVCFGMAYLESKGFIHRDLAARNCLVGDKH-------IVKVADFG---LTRYVM----------DDEYTSSG-TK
||.|.  .       .   ...|  ..  ||.||.|.||.|||||||||||.. .       ..|.||||   ..|.|           ...|.... ..
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

FPIKWAPPEVLHYT-RFSSKSDVWAFGILMWEVFSGGLAPYPAMSNVEVVDQVTRHN-YRMERPDHCPYQMYRIMKDCWR
 ||.|  ||.| .  ||..|||||.||...||....| .||| |||..|. ||.. . |||..|..|| ..||.|..||.
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWH
Kinase TEC.AA Src-Unclassified 554-789 43 8.5e-92 311.27 In-house 1-267 (284) Show / Hide 
Range on Protein: 554-789
Range on HMM: 1-267/284
Sequence Identity: 43% (116 aa)

LKILQELGRGQFGIVHLAKLTHNNRFVAVKRMQEG---SMSEEDFI--------DEAKVMKELQHENLVQLYGVTSAQRPMCIVTEYMSKGCLLSYLRTH
.. | .||||||| | ..|   .   |||| | .|    || | |          ||..||...| |||.||.| |   |  |.||||..| || .||. 
VHLLRKLGRGQFGEVWYGKW-RGKVDVAVKTMRPGHSETMSPEAFLHVKILNFCQEAQIMKKCRHQNLVHLYAVCSQEEPYYIITEYMINGSLLQWLREG

K-----FMLL------ENTAILIYMTQQVCFGMAYLESKGFIHRDLAARNCLVGDKH-----IVKVADFGLT--RYVMDDEYTS-SGTKFPIKWAPPEVL
      . ..       |  | ...  ||  || |||||. .|||||||| |.|..      .|||.||||   . . ||.|    | .||.||  ||  
GGQYLHIQDMSEETGRKNVLIGVDIAAQVASGMMYLESKKYVHRDLAARNVLIGHNNSNGVPVVKVCDFGLARKKLMQDDNYCMRTGAMFPWKWMAPECF

HYTRFSSKSDVWAFGILMWEVFSGGLAPYPAMSNVEVVDQVTRHNYRMERP--DHCPYQMYR-IMKDCW
 |  || ||||| .||| ||..  |  ||| | | ||. .| |  ||| .|    || . |  ||| ||
IYGNFSIKSDVWSYGILLWEIMTKGQTPYPGMHNREVLEHVERG-YRMPKPTNHYCPDYIYEDIMKKCW
Kinase TEC.AA SrcB 554-791 49 3.6e-88 298.38 In-house 1-235 (251) Show / Hide 
Range on Protein: 554-791
Range on HMM: 1-235/251
Sequence Identity: 49% (119 aa)

LKILQELGRGQFGIVHLAKLTHNNRFVAVKRMQEGSMSEEDFIDEAKVMKELQHENLVQLYGVTSAQRPMCIVTEYMSKGCLLSYLRTHKFMLLENTAIL
||. . || |||| | ..   .|.  |||| |..|.|| | |..|| |||.|||. ||.|| | .   |. |.|||| ||||| .|.| .   | .   |
LKLVKKLGAGQFGEVWMGYY-NNHMKVAVKTMKQGTMSPEAFLAEANVMKTLQHDRLVRLYAVVTKE-PIYIITEYMAKGCLLDFLKTDEGSKL-SLPKL

IYMTQQVCFGMAYLESKGFIHRDLAARNCLVGDKHIVKVADFGLTRYVMDDEYTSS-GTKFPIKWAPPEVLHYTRFSSKSDVWAFGILMWEVFSGGLAPY
| |. |.  ||||.| . .||||| | | || .  . |.||||| | . |.|||   | ||||||  || ...  |  |||||.||||. |.   |  ||
IDMSAQIAEGMAYIERMNYIHRDLRAANILVSETLCCKIADFGLARIIEDNEYTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLMEIVTYGRIPY

PAMSNVEVVDQVTRHNYRMERPDHCPYQMYRIMKDCWRE
| |.| ||. .. |  ||| ||| ||  .|.||. ||.|
PGMTNPEVIRNLER-GYRMPRPDNCPEELYNIMMMCWKE
Kinase TEC.AA Csk 554-789 45 1.5e-87 297.19 In-house 1-234 (251) Show / Hide 
Range on Protein: 554-789
Range on HMM: 1-234/251
Sequence Identity: 45% (109 aa)

LKILQELGRGQFGIVHLAKLTHNNRFVAVKRMQEGS-MSEEDFIDEAKVMKELQHENLVQLYGVTSAQR-PMCIVTEYMSKGCLLSYLRTHKFMLLENTA
|..... | | || | . ..   || |||| . . .    . |..||.|| .|.|.||||| ||   |   . ||.|||||| |. |||.    ...   
LHLGECIGHGEFGDVMQGEY--QNRKVAVKCIKCDGNGMAQAFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNLVDYLRSRGRHVITRRQ

ILIY-MTQQVCFGMAYLESKGFIHRDLAARNCLVGDKHIVKVADFGLTRYVMDDEYTSSGTKFPIKWAPPEVLHYTRFSSKSDVWAFGILMWEVFSGGLA
 |.. |   || ||.|||.| |.|||||||| || .  . || ||||..        |.. ||||||  || |   .||.||||| ||||.||..| | .
LLKFAM--DVCEGMCYLEQKKFVHRDLAARNILVSEDCVAKVSDFGLAKEECSQQDDSTSGKFPIKWTAPEALRHKKFSTKSDVWSFGILLWEIYSFGRV

PYPAMSNVEVVDQVTRHNYRMERPDHCPYQMYRIMKDCW
||| ..  .|| .| .  |||| |. || . | .||.||
PYPRIPLKDVVKHVEK-GYRMEAPEGCPPHVYKVMKQCW
Kinase TEC.AA Frk 554-794 46 1.1e-86 294.31 In-house 1-244 (260) Show / Hide 
Range on Protein: 554-794
Range on HMM: 1-244/260
Sequence Identity: 46% (115 aa)

LKILQELGRGQFGIVHLAKLTHNNRFVAVKRMQEGSMSEEDFIDEAKVMKELQHENLVQLYGVTSAQRPMCIVTEYMSKGCLLSYLR--THKFMLLENTA
......|| |||| |    |  |.  ||||... |.|  .||. ||..||.|.|  |.||| |   . |. |.|| | .| |. ||.  ..|   ..   
IQLIRRLGSGQFGEVWEG-LWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQ-MQ

ILIYMTQQVCFGMAYLESKGFIHRDLAARNCLVGDKHIVKVADFGLTR-YVMDDE--YTS-SGTKFPIKWAPPEVLHYTRFSSKSDVWAFGILMWEVFSG
.|. |. ||  |||||||. .||||||||| |||.. |.|.||||| |  . |.|  | |  | .|||||  ||  .| .|. |||||.||||. |.   
QLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITY

GLAPYPAMSNVEVVDQVTRHNYRMERPDHCPYQMYRIMKDCWRECAK
|  ||| | | ||...|  |.||| .|  || |.| || .||.. ..
GRMPYPGMTNAEVLQMV-DHGYRMPQPPNCPQQLYEIMLECWHSDPM
Kinase TEC.AA S_TKc 554-795 23 2.3e-42 148.0 SMART 1-231 (231) Show / Hide 
Range on Protein: 554-795
Range on HMM: 1-231/231
Sequence Identity: 23% (62 aa)

LKILQELGRGQFGIVHLAKLTHNNRFVAVKRMQEGSMSEEDFIDEAKVMKELQHENLVQLYGVTSAQRPMCIVTEYMSK--GCLLSYLRTHKFMLL---E
 .||...|.| || |.... .. .| ||.|..       |... | ...|. .|.|.|.||.|      ...|.||..   | |..|.. ..   |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

NTAILIYMTQQVCFGMAYLESKGFIHRDLAARNCLVGDKHIVKVADFGLTRYVMDDEYTSSGTKFPIKWAPPEVLHYTRFSS-KSDVWAFGILMWEVFSG
.     ....|.| ...|. |.|.|||||   | |. .   .|..|||| | .    .|  || .   . .||||    ..  |.|.|..|....| .. 
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPW---YMAPEVL---GYGKCKCDWWSCGCILYEMLC-

GLAPYPAMSNVEVVDQVTRHNYRMERPDHCPYQMYRIMKDCWR---------ECAK----------V
|  |.|     .. ...             . ..  ... |..         |. .          .
GYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase TEC.AA Pkinase 554-749 25 1.5e-35 126.74 Pfam 1-210 (293) Show / Hide 
Range on Protein: 554-749
Range on HMM: 1-210/293
Sequence Identity: 25% (56 aa)

LKILQELGRGQFGIVHLAKLTHNNRFVAVKRMQEGSMSEEDFID-----EAKVMKELQHENLVQLYGVTSAQRPMCIVTEYMSKG----CLLSYLR--TH
..|.. .|.| || | ...   ... ||||..   . ...  .      |...||.|.|.| |.||..    . ...|.||. .|     | .|..   |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KFMLLENTAILIYMTQQVCFGMAYLESKGFIHRDLAARNCLVGDKHIV----KVADFGLTR---YVMDDEYTSS-GTKFPIKWAPPEVLH-YTRFSSKSD
. ..      .. .  |.. |..|. |.|.|||||   |.|. ..  .    |..|||| .   |  .  .|.  || .   ...|||.  ..  ..|.|
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW---YMAPEVIRGGQYYGPKVD

VWAFGILMWEVFSGGL
.|..|....|...| .
MWSCGCILYEMLCGRP