Gene Trk (Sea Urchin)
Trk
Sequence
Protein domains of Trk.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| IG | Trk.AA | IG | 134-215 | 16 | 1e-06 | 29.14 | SMART | 1-58 (58) | Show / Hide |
Range on Protein: 134-215 Range on HMM: 1-58/58 Sequence Identity: 16% (14 aa) PKHLEIRDGESFNASCEVDGEPHPSLRWDVSRLVSPYQLVNVSKRQQIIMVQNASYKDT---GLLECIVSSVAGWRAA--EVNLTVK |. .. . ||. . .| | ...| . . |... |. | | .. .| . ...|||. PP-VTVKEGETVTLTC-VS-----QIWWY-------------------LTI-NVQPEDSQQHGTYYCQAT--HGQYWSIQGTTLTVQ |
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| I-set | Trk.AA | I-set | 128-161 | 35 | 0.000381 | 16.58 | Pfam | 1-34 (92) | Show / Hide |
Range on Protein: 128-161 Range on HMM: 1-34/92 Sequence Identity: 35% (12 aa) PSVNVTPKHLEIRDGESFNASCEVDGEPHPSLRW |.. .|| .|.. ||. . .|.|.|.| |. | PKFTQKPKDVEVQEGETARFECQVTGDPPPQVSW |
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| I-set | Trk.AA | I-set | 301-324 | 29 | 1.291607 | 4.6 | Pfam | 69-92 (92) | Show / Hide |
Range on Protein: 301-324 Range on HMM: 69-92/92 Sequence Identity: 29% (7 aa) DNGNYTLVVSNELGSDRKNISAIF | | || |..|..|.. . .. . DEGKYTCVATNSFGEAECTAELTV |
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| Kinase | Trk.AA | Trk | 451-721 | 69 | 6.6e-215 | 720.23 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 451-721 Range on HMM: 1-275/275 Sequence Identity: 69% (191 aa) IRFIGELGEGAFGVVCLGQCEHLPGADGPTMVAIKTLKDASVGDARTDFEREAELLTNLQHKNIVAFYGVCTDHEPFFMVFEYMENGDLNNYLKSRGPDA |....||||||||.|.|..|..|.......|||.|||||||. .||.||.|||||||||||..||.||||||||.|..||||||..||||.||...|||| IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKDASE-NARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDA DCFTRNQA---LLPLTVKELLYIAKQIASGMVYMASQHFVHRDMATRNCLVGDRLIVKIADFGMSRDVYS-TDYYRVGGHTMLPVRWMPPESIIYRTYSV .|....|. ..|||....|.||||||||||||||||||||||||||||||..|||||.|||||||||| |||||||.|||||.||||||||.||.... MCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRKFTY ESDVWSYGVVLWEIFEYGKQPWFGLSNHEVIEYIHNGIL-LDCPKGCPKEVYKIMLGSWQRQPTQRMLIKDLHDAI ||||||.|||.||.|.||||||..||||||||.||.|.. |..|..||.|||.||||.|||.|.|||.|||.||.| ESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII |
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| Kinase | Trk.AA | TyrKc | 451-721 | 41 | 1.1e-134 | 454.68 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 451-721 Range on HMM: 1-280/280 Sequence Identity: 41% (126 aa) IRFIGELGEGAFGVVCLGQCEHLPGADGPTMVAIKTLKDASVGDARTDFEREAELLTNL--QHKNIVAFYGVCTDH-------EPFFMVFEYMENGDLNN |... .|||||||.|..|. ..||.|.||. . | || |||.....| .|.|||..|||||.. || ..|.|||..|||.. ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD YLKSRGPDADCFTRNQALLPLTVKELLYIAKQIASGMVYMASQHFVHRDMATRNCLVGDRLIVKIADFGMSRDVYST-------DYYRV----GGHTMLP ||....|. |..|.||... |||.|| | .|....||| |.||||||....|||.|||.|||.|. ||||. ||.|||| YLRKHRPK------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP VRWMPPESIIYRTYSVESDVWSYGVVLWEIFEYGKQPWFG-----LSNHEVIEYIHNGILLDCPKG--------CPKEVYKIMLGSWQRQPTQRMLIKDL .|||.||.| |.... .|||||.||..|||| ||.||. | .|| |||||. .| ...|. ||.|.|.||. |...| .| ... IRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI HDAI |. . HECF |
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| Kinase | Trk.AA | Pkinase_Tyr | 451-721 | 43 | 2.8e-134 | 455.42 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 451-721 Range on HMM: 1-270/270 Sequence Identity: 43% (122 aa) IRFIGELGEGAFGVVCLGQCEHLPGADGPTMVAIKTLKDASVGDA--RTDFEREAELLTNL-QHKNIVAFYGVCT-DHEP--FFMVFEYMENGDLNNYLK |.|. .|||||||.|..| . . .. . ||.|.||. . .. | || |||.....| .|.||| .||||| . || ..|.|||..||| .||. ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR SRGPDADCFTRNQALLPLTVKELLYIAKQIASGMVYMASQHFVHRDMATRNCLVGDRLIVKIADFGMSRDVYSTDYY-RVGGHTMLPVRWMPPESIIYRT .. |||.|.|| .. |||.|| | .|....||| |.|||||.. ..|||.|||..||.|..||| |..|...||..||.||.| |. KHR---------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK YSVESDVWSYGVVLWEIFEYGKQP-WFGLSNHEVIEYI-HNGILLDCPKGCPKEVYKIMLGSWQRQPTQRMLIKDLHDAI ....|||||.||..|||| ||.|| . |.||.||.||| .| ..||..||.|.|..|. |. .| .| ...| . FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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| Kinase | Trk.AA | Ror | 451-711 | 46 | 5.5e-120 | 404.91 | In-house | 1-265 (308) | Show / Hide |
Range on Protein: 451-711 Range on HMM: 1-265/308 Sequence Identity: 46% (124 aa) IRFIGELGEGAFGVVCLGQCEHLPGADGPTMVAIKTLKDASVGDARTDFEREAELLTNLQHKNIVAFYGVCTDHEPFFMVFEYMENGDLNNYLKSRGPDA .|| ||||..||.| |. . .. .. |||||.|. . ..||..|..| |.| ||| |||| .| |.|||| .||| |..| | . VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDLHEFLIMRSPHS DCF-------TRNQALLPLTVKELLYIAKQIASGMVYMASQHFVHRDMATRNCLVGDRLIVKIADFGMSRDVYSTDYYRVGGHTMLPVRWMPPESIIYRT | . .| .. . |.|| |||.|| | .| |||||| |.||||||. . |||.||| .||.|| ||||. . ..|.|||.||.| | DHGCSSDDDRMVKSSLDHP---DFLHIAIQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAIMYGK YSVESDVWSYGVVLWEIFEYGKQPWFGLSNHEVIEYIHNGILLDCPKGCPKEVYKIMLGSWQRQPTQR |..||.||.|||||||. || ||. | || |||| | | || || .|| .| | | .| | FSEDSDIWSFGVVLWEIWSYGMQPYYGYSNQEVIEMIRNRHLLPCPHNCPTWIYSLMIECWHEIPSRR |
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| Kinase | Trk.AA | TK | 451-721 | 24 | 4.6e-115 | 387.35 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 451-721
Range on HMM: 1-486/486
Sequence Identity: 24% (120 aa)
IRFIGELGEGAFG---VVCLGQCEHLPGADGP--------------------TMVAIKTLKDASVGDARTDFE-------------REAELLTNLQ----
|... .||||.|| .|..|. . ... .|. | ||.|.||. . ... |. .||| . ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
-HKNIVAFYGVCTDH------------EPFFMVFEYMENGD----LNNYLKSRGPDADC-----------------------------------------
|.||| .|||||.. ||. .| |||..|| | .||... |.. .
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
-----------FTRNQALL-----------PLTVKELLYIAKQIASGMVYMASQ------HFVHRDMATRNCLVGDRLI-----------VKIADFGMS-
.| . | .||...|| .. |||.|| |..|. .||||| |.||||||.... .||||||.|
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR
-------RDVYSTDYYRVGG------------------------HTMLPVRWMPPESII---------YRTYSVESDVWSYGVVLWEIFEYGKQPWFG-L
||.|| |.|.. . ..||.|||.||.. |.... .|||||.||..|||| ||..|. | .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM
SN---------HEVIEYIHNG--------------ILLDCPKGCP--------------KEVYKIMLGSWQRQPTQRMLIKDLHDAI
|| .||.||. .| . .|..|| .|.| .|. |...| .| ..||...
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
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| Kinase | Trk.AA | Musk | 451-721 | 43 | 2e-113 | 376.23 | In-house | 1-282 (282) | Show / Hide |
Range on Protein: 451-721 Range on HMM: 1-282/282 Sequence Identity: 43% (124 aa) IRFIGELGEGAFGVVCLGQCEHLPGADGPTMVAIKTLKDASVGDARTDFEREAELLTNLQHKNIVAFYGVCTDHEPFFMVFEYMENGDLNNYLKSRGPDA | .. ..|||||| | | . ||||.| ||| . ||.||| .. | ||| ||| | . |||| ||||..|.|. | . IIYVRDIGEGAFGRVFQARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSCSPHR DCFTRNQAL-----------LPLTVKELLYIAKQIASGMVYMASQHFVHRDMATRNCLVGDRLIVKIADFGMSRDVYSTDYYRVGGHTMLPVRWMPPESI | | . ..| ..| .||||| || |. |||||.||||||.... |||||||.|| .|. |||. . |.|||||||| TCSRTHQDRGMRAQVSSPGPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESI IYRTYSVESDVWSYGVVLWEIFEYGKQPWFGLSNHEVIEYIHNGILLDCPKGCPKEVYKIMLGSWQRQPTQRMLIKDLHDAI | ...|||||.|||.||||| |. ||..|.. ||| || .| | || || .||..| ||..| | ...|. | WYNQFTYESDVWAYGVCLWEIFSYALQPYYGMTHEEVIYYIRQGNILSCPENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI |
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| Kinase | Trk.AA | InsR | 451-723 | 39 | 5.4e-100 | 336.57 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 451-723 Range on HMM: 1-278/278 Sequence Identity: 39% (109 aa) IRFIGELGEGAFGVVCLGQCEHLPGADGPT--MVAIKTLKDASVGDARTDFEREAELLTNLQHKNIVAFYGVCTDHEPFFMVFEYMENGDLNNYLKSRGP | | |.|.|.|| | .| . .. . . .||||.... |..| ||. . ....| .|||. .| | | |. ||| .|| || | IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP DAD--CFTRNQALLPLTVKELLYIAKQIASGMVYMASQHFVHRDMATRNCLVGDRLIVKIADFGMSRDVYSTDYYRVGGHTMLPVRWMPPESIIYRTYSV .. .|. . . ... | .|..|| | |. ||||| | |||.| . . |||.|||| ||.| .|||| || |||||||.|||. .. EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVFTT ESDVWSYGVVLWEIFEYGKQPWFGLSNHEVIEYI-HNGILLDCPKGCPKEVYKIMLGSWQRQPTQRMLIKDLHDAISQ |||||.||||||. | || |||| .| .|| .| .|. | .||. ....| || || | . .|. . . . HSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD |
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| Kinase | Trk.AA | UTK | 451-721 | 34 | 4.5e-97 | 328.79 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 451-721 Range on HMM: 1-296/296 Sequence Identity: 34% (105 aa) IRFIGELGEGAFGVVCLGQCEHLPGADGPTMVAIKTLK-DASVGDART---DFEREAE---LLTNLQ-HKNIVAFYGVCTDHEPFFMVFEYMENGDLNNY ... .||.||||.|... .. .. . ||.|... .|. .... || .|| .. ... | |.. ..||||. ||. .| |||||||| .| VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY LKSRGPDADCFTRNQALLPLTVKELLYIAKQIASGMVYMASQHFVHRDMATRNCLVGDR-------LIVKIADFG---MSRDVY---------STDYYRV | . .|... .. . || ..|. | .||.|| |..|..||||| | |||||.. ...|||||| |||.|. ...||. LRRHRPTPP-----ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMA GGHTMLPVRWMPPESIIYR-TYSVESDVWSYGVVLWEIFEYGKQPWFGLSNHEVIEYIHNG--ILLDCPKGCPKEVYKIMLGSWQRQPTQRMLIKDLHDA . ...|.||| ||..... ... |||||.|||.|||. .|..|. |.||..|.. ..|| .. ||..|| .||..|. |. | | ..|| .. QHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQ I . M |
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| Kinase | Trk.AA | TK-Unique | 451-721 | 33 | 8.6e-90 | 304.62 | In-house | 1-294 (294) | Show / Hide |
Range on Protein: 451-721 Range on HMM: 1-294/294 Sequence Identity: 33% (99 aa) IRFIGELGEGAFGVVCLGQCEHLP-GADGPTMVAIKTLKDASVGDARTDFEREAELLTNLQ-HKNIVAFYGVCTDH-EPFFMVFEYMENGDLNNYLKSRG ... ..|||||| |. |. . .. . | .. ||.|.||| . . . || .|.... .| |.||| ..|.||. ||.....||...|.| .||.... LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR PD-------------ADCFTRNQALLPLTVKELLYIAKQIASGMVYMAS--QHFVHRDMATRNCLVGDRLIVKIADFGMSRDVY-STDYYRVGGHTMLPV |. .. .. . . |.. | |. .|.|||.|| |.|| ...|||| ..||.|.......||.||||.|||| ..| . .. ..|. PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI RWMPPESII--YRTY-SVESDVWSYGVVLWEIFEYGKQPWFGLSNHEVIEYIHNGILLDCPKGC-PKEVYKIMLGSWQRQPTQRMLIKDLHDAI |||.|||. ...| . .|||||.||..|||| .|..| |... ...| | .| .. |..| ..|.|..| ||. |..| . .. . . RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL |
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| Kinase | Trk.AA | Src | 451-721 | 36 | 1.2e-85 | 290.81 | In-house | 1-255 (255) | Show / Hide |
Range on Protein: 451-721
Range on HMM: 1-255/255
Sequence Identity: 36% (100 aa)
IRFIGELGEGAFGVVCLGQCEHLPGADGPTMVAIKTLKDASVGDARTDFEREAELLTNLQHKNIVAFYGVCTDHEPFFMVFEYMENGDLNNYLKSRGPDA
|... .||.| || | | | | ||.|||| .. . ..| .||.....|.|...|. | ||.. ||.. | |||..| | |||
IKLCRKLGQGQFGEVWMGYWN------GNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-----
DCFTRNQALLPLTVKELLYIAKQIASGMVYMASQHFVHRDMATRNCLVGDRLIVKIADFGMSRDVYS--TDYYRVGGHTMLPVRWMPPESIIYRTYSVES
.. | ...|...| |.|.|| |. |. ..||| | || |||. ...|.|||| | . | | ..|..|. || | |..... |
-----DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKS
DVWSYGVVLWEIFEYGKQPWFGLSNHEVIEYIHNGILLDCPKGCPKEVYK-IMLGSWQRQPTQRMLIKDLHDAI
||||.|. |.||. ||. | | .||||.. . .| . ||..||.|.|. ||| |...| || . |..
DVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
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| Kinase | Trk.AA | Tec | 451-723 | 39 | 6.7e-83 | 281.72 | In-house | 1-254 (254) | Show / Hide |
Range on Protein: 451-723 Range on HMM: 1-254/254 Sequence Identity: 39% (109 aa) IRFIGELGEGAFGVVCLGQCEHLPGADGPTMVAIKTLKDASVGDARTDFEREAELLTNLQHKNIVAFYGVCTDHEPFFMVFEYMENGDLNNYLKSRGPDA . |. ||| | |||| ||. | ||||..| | || ||. ..|.| . | .||||. . | ..|.||||.| | |||.... LTFMKELGSGQFGVVHLGKWRHQ------YDVAIKMIKEGSMSEE--DFIEEAKVMMKLSHPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHK--- DCFTRNQALLPLTVKELLYIAKQIASGMVYMASQHFVHRDMATRNCLVGDRLIVKIADFGMSRDVYSTDYYRVGGHTMLPVRWMPPESIIYRTYSVESDV | .|.|. ||.. ... || | .. |.||| | ||||||| .||..||||.| | .| .| | ||.| ||| | || ||| HHFQKNMAI-------LLEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDFGMTRYVLDDQYTSSVG-TKFPVKWCPPEVFHYSRYSSKSDV WSYGVVLWEIFEYGKQPWFGLSNHEVIEYIHNGILLDCPKGCPKEVYKIMLGSWQRQPTQRMLIKDLHDAISQ |..|| ||.| ||.|. .|| ||.| . |. | |. |....|.|| |. .| .| ..| ..| . WAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPHLCSMHIYQIMYHCWHEKPEERPTFQQLLRQITE |
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| Kinase | Trk.AA | ALK | 451-711 | 41 | 6.7e-83 | 281.71 | In-house | 1-261 (273) | Show / Hide |
Range on Protein: 451-711 Range on HMM: 1-261/273 Sequence Identity: 41% (112 aa) IRFIGELGEGAFGVVCLGQCEHLPGADGPTMVAIKTLKDASVGDARTDFEREAELLTNLQHKNIVAFYGVCTDHEPFFMVFEYMENGDLNNYLKSRGPDA | . || |||| | || |.|| | ||.|||. . || || . . .| |.| |.| . | . | |||| ||. .|. ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPYMIVLEYMEGGDMKSFLR------ DCFTRNQ--ALLPLTVKELLYIAKQIASGMVYMASQHFVHRDMATRNCLV---GDRLIVKIADFGMSRDV-YSTDYYRVGGHTMLPVRWMPPESIIYRTY .| . . . .|| | || ... .| | |. ..||.||| | |||| | ..|||||||.||. | .|||| || .|.|| ||||| . . ECRPHPESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRKGGRAMMPVKWMPPEAFMDGIF SVESDVWSYGVVLWEIFEYGKQPWFGLSNHEVIEYIHNGILLDCPKGCPKEVYKIMLGSWQRQPTQR .||||.|| .|||| | | | .| ||.| . | .| |..|| ||.|| || || | TSKTDVWSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRNCPQPVYRIMTQCWQHQPEDR |
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| Kinase | Trk.AA | S_TKc | 451-725 | 22 | 1.2e-47 | 165.55 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 451-725 Range on HMM: 1-231/231 Sequence Identity: 22% (65 aa) IRFIGELGEGAFGVVCLGQCEHLPGADGPTMVAIKTLKDASVGDARTDFEREAELLTNLQHKNIVAFYGVCTDHEPFFMVFEYMEN--GDLNNYLKSRGP ... ..|.||||.|.... . |||| .| ...|| ..| . .|.||| .|.|. | . ..||.||... ||| |.|.||. YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR DADCFTRNQALLPLTVKELLYIAKQIASGMVYMASQHFVHRDMATRNCLVGDRLIVKIADFGMSRDVYSTDYYRVGGHTMLPVRWMPPESIIYRTYSV-E .| |.. . ....||.... |. |....||| | |. . .||.|||..| . . .|.|| . |. . HGLRF-------PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCK SDVWSYGVVLWEIFEYGKQPWFGLSNHEVIEYIHNGILLDCPKGCPKEVYKIMLGSWQRQPTQRMLIKDLHD-----AISQLS .|.|| |..|.| . |. |. .. . ... ..|. .. . .|. |..|. . .. .. . CDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | Trk.AA | Pkinase | 451-721 | 21 | 1.9e-45 | 161.81 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 451-721 Range on HMM: 1-293/293 Sequence Identity: 21% (69 aa) IRFIGELGEGAFGVVCLGQCEHLPGADGPTMVAIKTLKDASVGD--ARTDFE-REAELLTNLQHKNIVAFYGVCTDHEPFFMVFEYMENG----DLNNYL ..... .|.|.||.|.. | | . .||.|..| . . .|.. .|.... .|.|.||| .|....|. ||.||.|.| || |. YHIGRKIGSGSFGCVYK--CHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI KSRGPDADCFTRNQALLPLTVKELLYIAKQIASGMVYMASQHFVHRDMATRNCLVGDRLIV----KIADFGMSRDVYSTDYYRVGGHTMLPV---RWMPP . |. ... .. .|. ...||..|. |. |. ..|||. |.|. .. . ||.||| .. .. | .. .. .. ..|.| ST--------WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAP ESII-YRTYSVESDVWSYGVVLWEIFEYGKQPWFGL----SNHEVIEYIHNGIL----LDCPKGCP-------------------KEVYKIMLGSWQRQP | | .. |. ..|.||.|..|.| . |. |. | . |. .. | . |.|. |. .| ... . ... | EVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDP TQRMLIKDLHDA--I ..| .... . KKRPTAEQILQHPWF |
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