Gene TAK1 (Sea Urchin)

TAK1

Species: Sea Urchin
Alias: TAK1, SPU_002696, Spk221
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: TAK1

Sequence

Name Sequence Type Origin Length Description Download
TAK1.AA Protein None 403 None Fasta, JSON
TAK1.kin_dom Protein Kinase Domain None 229 None Fasta, JSON

Protein domain

Protein domains of TAK1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TAK1.AA TAK1 19-248 50 9.5e-170 570.23 In-house 1-265 (284) Show / Hide 
Range on Protein: 19-248
Range on HMM: 1-265/284
Sequence Identity: 50% (134 aa)

IDFEKVVGKGAFGVVSKASWRGMNVAVKMIE------SEEEIKAFRVEVMQLSRVDHPNIVKLYG--ACTTQPVCLVMEFAEGGSLYNVLHSSQPQPIYK
|..|..||||..|||.||.||....|||..|      .|.|.|....|.||.||||||||.||||  ||..|..|||||....|||.|.||...|...|.
IQNEHFVGKGTYGVVCKAKWRNKEIAVKRFEFIKYSSEECEQKNIEREIMQWSRVDHPNIIKLYGMYACHRQCQCLVMEYMDCGSLHNFLHGAKPKWEYT

AAHAMSWALQCAKGVDYLHSMKPKKLIHRDLKPANLLLMSGGTVLKICDFGTACDFQTYMTNNKGSAAWMAPEV----------------------FEGR
.||||||..|||.||.|||||.||..||||.||.|.||......||||||||.||....||.|.|...||||||                      |...
HAHAMSWMHQCAQGVAYLHSMQPKPQIHRDIKPQNMLLCNKHRTLKICDFGTFCDMHQMMTCNRGTCRWMAPEVRELFDFKSNRIIINQPTGFQKVFRCE

TYSEKCDIFSWGVILWEVISRRKPFDDIGGP--AFRIMWAVHNGRRPPLIRN---IPKPLDKLMT
.|..||||.|||.|.||||||..|.|.|..|  |.|||||.|||.|||...|   .||.....|.
KYNMKCDIYSWGIIMWEVISRKHPYDHIMNPNSAYRIMWAIHNGNRPPMETNRSDCPKRIEQFMK
Kinase TAK1.AA MLK 19-248 40 4e-129 435.29 In-house 1-271 (291) Show / Hide 
Range on Protein: 19-248
Range on HMM: 1-271/291
Sequence Identity: 40% (110 aa)

IDFEKVVGKGAFGVVSKASWRGMN-----VAVKMIE--------SEEEIKAFRVEVMQLSRVDHPN----IVKLYGACTTQ-P-VCLVMEFAEGGSLYNV
|.|....|.|.||.| |. ||...     ||||...        ...|...|. |...|....|||    |...||.|. . . .|.|||..||||||||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHSSQPQPI-----------YKAAHAMSWALQCAKGVDYLHSMKPKKLIHRDLKPANLLLMS-----GGTVLKICDFGTACDFQTY---MTNNKGSAAWM
||. ....            |. .|||.||||||.|..|||||.||..||||||. |.|..      ....||||||||..|...    |..|.|..|||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APEVF---EGRTYSEKCDIFSWGVILWEVISRRKPFDDIGGPAFRIMWAVHNGRRPPLIRNIPKPLDKLMT
||||.   .. .||||||..||||.|||...|. |....  |.....|...|| |||.. ..|... |||.
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMK
Kinase TAK1.AA TKL 25-248 26 2.7e-90 306.3 In-house 1-344 (364) Show / Hide 
Range on Protein: 25-248
Range on HMM: 1-344/364
Sequence Identity: 26% (93 aa)

VGKGAFGVVSKASWRG----------MNVAVKMIESEE-----------------------------EIKAFRVEVMQLSRVDHPNIVKLYGACTTQP--
.|.|.||.| |. |||            ||||.. |..                             . . ...|.|..|| .|||||...|.|.  |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VCLVMEFAEGGSLYNVLHSSQPQPIYKAAHAMSWALQCAKGVDYLHSMKP-----KKLIHRDLKPANLLLMSGGTV------------
             |.|||...||||...||           . ..|||..|.|..|||||.|     ...||||||..|.|. . .|.            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-LKICDFGTACDFQTY---------------------MTNNKG-SAAWMAPEVFEGR----------------TYSEKCDIFSWGVILWEVISRRKPFDD
 .||||||.. ....                      .|.... . .||||||..|                 .||||||..|.|..|||...|..|..|
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

IGGP--------AFRIMWAVHNGRRPPLI------------RNIPKPLDKLMT
.. .           .|.....|.|||.              ..|... |||.
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQ
Kinase TAK1.AA Dicty4 19-248 35 6.4e-60 198.58 In-house 1-253 (277) Show / Hide 
Range on Protein: 19-248
Range on HMM: 1-253/277
Sequence Identity: 35% (90 aa)

IDFEKVVGKGAFGVVSKASWRGMNVAVKMI----ES--EEEIKAFRVEVMQLSRVDHPNIVKLYGACTT---QP--VCLVMEFAEGGSLYNVLHS-----
|..|.  |||.|| | |..|||  ||||.     .   |.....|| ||  ..   ||||....||||    .|  .| |.|.   |.||..||.     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

--SQPQP--IYKAAHAMSWALQCAKGVDYLHSMKPKKLIHRDLKPANLLLMSGGTVLKICDFGTAC------DFQTYMTNNKGSAAWMAPEVFEGRTYSE
  | . .   .|.|  |  |. .|.|. .||.  |   ||||||..| ||..   . |.|||| .       |... ..  .|...||||||  .. | |
QQSIKLDWPLIKRA--MRMAFDAARGMNWLHCCNP-VIIHRDLKSHN-LLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE

KCDIFSWGVILWEVISRRKPFDDIGGPAFRIMWAVHN-GRRPPLIRNIPKPLDKLMT
| | .| | .|||   |  |.   . | . .  || | . |||.  . |... .|..
KADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQ
Kinase TAK1.AA TKL-Unique 21-248 33 6.8e-58 198.65 In-house 1-270 (290) Show / Hide 
Range on Protein: 21-248
Range on HMM: 1-270/290
Sequence Identity: 33% (90 aa)

FEKVVGKGAFGVVSKASWRGMNVAVKMIE-----SEEEIKAFRVEVMQLSRVD-HPNIVKLYGACT----TQP-VCLVMEFAEGGSLYNVLH-----SSQ
| ...| |..|.| |. |||  ||.| ..     | |... |. ||  ... . |||||...|.|.    ..|  |.|||. .|||||.|||     .  
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

PQPIYK--AAHAMSWALQCAKGVDYLHSMKPKKLIHRDLKPANLLLMSGG----TVLKICDFGTACDFQTYM---TNN----------KGSAAWMAPEVF
  . .|   .  .. |...|.| .|||. .|.  ||||||. |.|. ..        ||||||. . |.. .   |||          .||. ||||||.
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGL-SKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

EG--RTYSEKCDIFSWGVILWEVISRRK------PFDDIGGPAFRIMWAVH-NGRRPPLIRNIPKPLDKLMT
..   .||||.|..| |..||| ..|        |....   . . | ..   . |||.  ..|| . .|..
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQ
Kinase TAK1.AA Pkinase 19-215 33 1.1e-55 196.17 Pfam 1-214 (293) Show / Hide 
Range on Protein: 19-215
Range on HMM: 1-214/293
Sequence Identity: 33% (73 aa)

IDFEKVVGKGAFGVVSKASWRGMN--VAVKMIESEEEIKAFRV------EVMQLSRVDHPNIVKLYGAC-TTQPVCLVMEFAEGG----SLYNVLHSSQP
. .....|.|.||.| |. ..| .  |||| |. ..| . ...      |.  . |..|||||.||... . . ...|||..|||    .|. ...  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-WR

QPIY--KAAHAMSWALQCAKGVDYLHSMKPKKLIHRDLKPANLLLMSGGTV---LKICDFGTACDF---QTYMTNNKGSAAWMAPEVFE-GRTYSEKCDI
.  .     .. ....| ..|..|.|||   . |||||||.|.|. . |..   .|||||| |. |   .. ||   |.  .|||||   |. |. |.|.
HGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

FSWGVILWEVISRRKPFDD
.| |.||.|....| ||..
WSCGCILYEMLCGRPPFPG
Kinase TAK1.AA Pkinase_Tyr 19-234 31 1.5e-51 175.18 Pfam 1-236 (270) Show / Hide 
Range on Protein: 19-234
Range on HMM: 1-236/270
Sequence Identity: 31% (76 aa)

IDFEKVVGKGAFGVVSKASWR------GMNVAVKMI--ESEEE---IKAFRVEVMQLSRV-DHPNIVKLYGACT--TQP--VCLVMEFAEGGSLYNVLHS
| | |. |.||||.| |. |.      .. |||||.   . .|   ...|  |.  ..   .|||||.|||.||   .|  ...|||....|.|.. |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

S-QPQPIYKAAHAMSWALQCAKGVDYLHSMKPKKLIHRDLKPANLLLMSGGTVLKICDFGTACDF-----Q-TYMTNNKGSAAWMAPEVFEGRTYSEKCD
   ...  .  .  ....| ||| .||.|..   .|||||   | |. ... | |||||| | |        .  .. |    |||||..  . ...| |
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENN-VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

IFSWGVILWEVIS-RRKP-FDDIGGPAFRIMWAV-HNGRRPP
. | || .||...  ..| . ..  . .... ..  .|.| |
VWSFGVLMWEIFTYGEQPTYPGM--SNEEVYEYIYEDGYRMP
Kinase TAK1.AA TK 19-209 18 1.5e-51 170.68 In-house 1-390 (486) Show / Hide 
Range on Protein: 19-209
Range on HMM: 1-390/486
Sequence Identity: 18% (74 aa)

IDFEKVVGKGAFG---VVSKASWRGMN---------------------------VAVKMI-----ESEEEIKA--------------FRVEVMQLS--RV
| ..|. |.|.||   .| |. |||.|                           |||||.     .|.|| ..              .  | ....    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

DHPNIVKLYGACTTQ-------------PVCLVMEFAEGGS----LYNVLHSSQPQPIY-----------------------------------------
.|||||.|||.|| .             |...|||....|.    | . |... |  .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------KAAHAMS-------------------WALQCAKGVDYLHSMKP---KKLIHRDLKPANLLLMSGGT----------VLKICDFGTA--
              ..  .                   ...| |.|  ||||..    ....||||   | |. ....          | ||.||| .  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----------CDFQTYMTNNKGSAA-------------------------WMAPEVFEGRT---------YSEKCDIFSWGVILWEVISR
           |   | ....| .                          |||||....|.         ...| |..|.|| .||. ..
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTY
Kinase TAK1.AA S_TKc 19-324 21 3.2e-51 177.4 SMART 1-231 (231) Show / Hide 
Range on Protein: 19-324
Range on HMM: 1-231/231
Sequence Identity: 21% (73 aa)

IDFEKVVGKGAFGVVSKASWRG--MNVAVKMIESEEEIKAFRVEVMQLSRVDHPNIVKLYGACTTQPVCLVMEFAEG--GSLYNVLHSSQPQPI---YKA
 .. ...||||||.| |. ...    ||.|.|      . .| |.  |.. .||||||||... .. ...|||...|  |.|. .... ....    .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

AHAMSWALQCAKGVDYLHSMKPKKLIHRDLKPANLLLMSGGTVLKICDFGTACDFQTYMTNNKGSAAWMAPEVFEGRTYSE-KCDIFSWGVILWEVISRR
 || ... | .....|.||..    |||||||.|.|| .   ..|||||| |. .    |   |.  .|||||.    |.  |||. | |.||.| ....
-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE---HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

KPFDDIGGPAFRIMWAVHNGRRPPLIRNIPKPLDKLMTSDSSPVHSSTKDQQKRHSVDLLDLRVDNDNSANDDSDVSMAYSTLEPHLQPLPPNPNSRESQ
 ||.      ....  .                                                                              |.|  
PPFP----QMQMMFKKIG-----------------------------------------------------------------------------SPEAK

DIFDEHMR-----------MA-------QEFL
|. .  ..           ..        ...
DFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase TAK1.AA LRRK 19-249 27 4.1e-51 176.14 In-house 1-330 (351) Show / Hide 
Range on Protein: 19-249
Range on HMM: 1-330/351
Sequence Identity: 27% (93 aa)

IDFEKVVGKGAFG-VVSKASWRG----------------------------MNVAVKMIESE------------------------------------EE
. .|. .|.|.|| .| .| |||                             .||.| .. .                                    . 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

IKAFRVEVMQLSRVDHPNIVKLYGACTTQPVCLVMEFAEGGSLYNVLHSSQPQPIYKAAH-AMSW------ALQCAKGVDYLHSMKPKKLIHRDLKPANL
   || ||  .|. .|||||.|.| |  .| |.|||.|  |.|| .||...  ..       .||      ||| |||..|||| .| ..||||||. | 
FREFRHEVWIMSHLNHPNIVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGF-HFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSPNI

LL--MS---------GGTVLKICDFGTACDFQTYMTN-NKGSA---AWMAPEVFEGR---TYSEKCDIFSWGVILWEVISRR-KPFDDIGGP-----AFR
||  ..           .. ||.|||.   ||.. .   ||.     |||||.  .    .|.|| |..| |.|||| ..|.  |||.. ..       .
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQ

IMWAVHNGRRPPLIRN-IPK-----PLDKLMTS
|  .. .|.||..  .  |       ...|...
IEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQH
Kinase TAK1.AA TyrKc 19-270 27 6.3e-45 156.49 SMART 1-280 (280) Show / Hide 
Range on Protein: 19-270
Range on HMM: 1-280/280
Sequence Identity: 27% (81 aa)

IDFEKVVGKGAFGVVSKASWRGMNVAVKMIESEEEIKAFRVEVMQLSRV--DHPNIVKLYGACTT--------QPVCLVMEFAEGGSLYNVLHSSQPQPI
| ..|. | ||||.| |. |. ..|||||. ..  ...|. |   ....  .|||||.|||.||.        .|...|||....|.| . |....|.  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--

YKAAHAMSWALQCAKGVDYLHSMKPKKLIHRDLKPANLLLMSGGTVLKICDFGTACDF----------QTYMT----NNK--GSAAWMAPEVFEGRTYSE
 . ..  |...| |.| .||||.   ..|||||   | |. ... . ||.||| . |           ..|..    . |      |||||..  .....
LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KCDIFSWGVILWEVISR-RKPFDD-IG--GPAFRIMWAVHNGRRPPLIRN--------IPKPLDKLMTS--DSSPVHSSTKDQQKRHSVDLL
| |..|.|| .||. ..  .|  . |    ......  | .|.|.|   |         |. . ..|..  .  |    |  .     ....
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI----HECF
Kinase TAK1.AA ZAK 19-227 39 4e-44 152.9 In-house 1-216 (257) Show / Hide 
Range on Protein: 19-227
Range on HMM: 1-216/257
Sequence Identity: 39% (90 aa)

IDFEKVVGKGAFGVVSKASWRGMN-----VAVK---MIESEEEIKAFRVEVMQLSRVDHPNIVKLYGACTTQPV--CLVMEFAEGGSLYNVLHSSQPQPI
| |   .| | || | .| |         .|||    || | ||         || . | ||.  || |   |     | |.|| ||||   || . | .
IQFFDHCGVGTFGSVYRANWISQDGSQREIAVKKVFKIEKEAEI---------LSKIRHRNIIQFYGICKEPPNDYFIVTEYAEKGSLYDYIHSNRSQEM

Y------KAAHAMSWALQCAKGVDYLHSMKPKKLIHRDLKPANLLLMSGGTVLKICDFGTACDFQTYMTNN--KGSAAWMAPEVF-EGRTYSEKCDIFSW
          | | || | |||. |||   | | ||||||  |  .   | |.|||||||  ||    |     | ..|||||.       .| ||..|.
DSSSGGNSMDHIMKWATQIAKGMHYLHMDAPDKIIHRDLKSRNVVIDKNG-VCKICDFGTSRDFHHHCTHMSWVGTFPWMAPEMILQSEPVTETCDVWSY

GVILWEVISRRKPFDDIGGPAFRIMWAV
||.|||. .|  |. |  .  |.| | .
GVVLWEMLTREVPYKDYEE--FQIFWMI
Kinase TAK1.AA CZAK 19-216 35 3e-43 149.99 In-house 1-225 (279) Show / Hide 
Range on Protein: 19-216
Range on HMM: 1-225/279
Sequence Identity: 35% (81 aa)

IDFEKVVGKGAFGVVSKASWRGMNVAVKMI-------ESE-EEIKAFRVEVMQLSRVDHPNIVKLYGACTTQP---VCLVMEFAEGGSLYNVL--HSS--
  |....|.| || | || |||  ||.| |        .|  |   |  ||  .|   |||.|   |||.       | |||. .||||   |  |..  
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

QPQPIYKAAHAMSWALQCAKGVDYLHS-MKPKKLIHRDLKPANLLLMSGGT------------VLKICDFGTA---CDFQTYMTNNKGSAAWMAPEVFEG
.. |.     ... |.  |.|  |||   ||   .||||   | || .  |            . || |||         . ||   |. .|||||.| |
KQNPHL----QWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKG

RTYSEKCDIFSWGVILWEVISRRKPFDDI
  |.|| |..|.| |||..|  . |  ..
ENYTEKVDVYSFGMILWCIITCDQPYQNM
Kinase TAK1.AA Dicty5 19-216 35 7.7e-42 141.78 In-house 1-206 (260) Show / Hide 
Range on Protein: 19-216
Range on HMM: 1-206/260
Sequence Identity: 35% (74 aa)

IDFEKVVGKGAFGVVSKASWRGMNVAVKMIESEE----EIKAFRVEVMQLSRVD--HPNIVKLYGACTTQPVC--LVMEFAEGGSLYNVLHSSQP---QP
. | ...  || | | .   .|| ||.|   .|     ..  |  ||  .| ..  |||... ||| .        | |.   ||| | |        ||
VSFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP

IYKAAHAMSWALQCAKGVDYLHSMKPKKLIHRDLKPANLLLMSGGTVLKICDFGTAC--DFQTYMTNNKGSAAWMAPEVFEGRTYSEKCDIFSWGVILWE
|      .. |.  |..  .||||     ||||||  | |.    .. || ||||    | .  || . |  .|||.|.| |..| .|||..|.|..|||
IA-YFQQLHMAIDIAQSMRHLHSM---NIIHRDLKSMNFLITENWKI-KIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWE

VISRRKPFDDI
.. |  |.|.|
MFTRKEPYDNI