Gene ANKK2 (Sea Urchin)
ANKK2
Sequence
Protein domains of ANKK2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | ANKK2.AA | RIPK | 79-338 | 51 | 3.6e-171 | 574.95 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 79-338 Range on HMM: 1-290/290 Sequence Identity: 51% (148 aa) LGGGSFGEVFKAVHKVHGDVAVKLAKPGKG------DQLKMHQKEARKHGLSLTCDYIVAIKGFVKCEEDTCPCGLLGIVMQYMENGSLWDFRISEW--Q .|||.|||||||.|...||...|..||.| || .|.|||..|| .|.|..|| |.||..|||..|.|.|.||||.||||||||.|....| | VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ PFPDLWPLTNRMVYQISCGMHFLHSKN--IIHRDLKLENVLVDGDLHVKIADLGLATNLQTS--SGDRC-------------WGTDSHKPPEAFRTDLPN ..||.|||..||...|||||..|||.| |||||||.||.|||...||||||.||||....| .||| |||.|..|||.||||... HHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKK STKVVTPKYDVYSFAMTLYELLTGIHPYSDRGFDMMKLLKVEAKQPPCLQPVPVNAPKD-----LIEVMQECWSYEANERPNFREIRDRV ..|||||||||||||....|.||..|||.||...||......... |||||||.. |.. .||.||.||....|.||.|.|..... PIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT |
|||||||||
| Kinase | ANKK2.AA | TKL | 79-338 | 24 | 2.5e-89 | 303.1 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 79-338 Range on HMM: 1-364/364 Sequence Identity: 24% (92 aa) LGGGSFGEVFKAVHKVHG---------DVAVKLAKPGKGD--------------------------QLKMHQKEARKHGLSLTCDYIVAIKGFVKCEEDT .| |.||||.|.... .| ||||| | | ... . .| .. ..| .. || ..|...|.... IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG C-------PCGLLGIVMQYMENGSLWDFRISEWQPFPDLWPLTNRMVYQISCGMHFLHS--------KNIIHRDLKLENVLVDGDLH------------- | |.| |.|||.|...|||... . |... |....|..||..||| ..||||||| .|.||| ... CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW -VKIADLGLATNLQTSSGDRCW---------------------GTDSHKPPEAFRTDLPNSTKV----------VTPKYDVYSFAMTLYELLTGIHPYSD .||.|.||......|... .. || . .||..| ..... || ..| |||||.. |.|.||. .||.| CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD RGFDMMK---------LLKVEAKQPPCLQPVPVN---------APKDLIEVMQECWSYEANERPNFREIRDRV ....|. . .. ...| . |.. | .|..... ||.||......||.| || .| YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
|||||||||
| Kinase | ANKK2.AA | TK | 73-338 | 17 | 7.4e-45 | 147.85 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 73-338
Range on HMM: 1-486/486
Sequence Identity: 17% (85 aa)
ELEGCHLGGGSFG---EVFKAVHKVHG--------------------------DVAVKLAKPGKGDQLKMHQK-----------------EARKHGL-SL
| || | || ||.|. . .. .|||| |.| ... .... |. . . .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
TCDYIVAIKG-FVKCEEDTCPC-----GLLGIVMQYMENGS--------LWDFR----------------------------------------------
.. || . | .. |. .| . . ||| ||..|. |.. |
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
----ISEWQPFPDLWPLTNR------------------MVYQISCGMHFLHSK------NIIHRDLKLENVLVDGDLH-----------VKIADLGLATN
|.. | ... | .. | .||.||| .|||| |..|||| |.||. ... .|||| ||. .
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ
------LQTSSGDRCWGTDSHK------------------------------PPEAFRTDLPNST---KVVTPKYDVYSFAMTLYELLT-G-IHPYSDRG
|.| . ..|.. .||.... . . .. |.| ||.|| ...|..| | .| .
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS
----------FDMMKLLKVE-----------------AKQPPCLQ------PVPVNAPKDLI-EVMQECWSYEANERPNFREIRDRV
..|..|. . .. | | . | ..| ... ..||.||.|....||.|......
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMH-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
|
|||||||||
| Kinase | ANKK2.AA | Pkinase | 73-338 | 23 | 1e-39 | 141.53 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 73-338 Range on HMM: 1-293/293 Sequence Identity: 23% (74 aa) ELEGCHLGGGSFGEVFKAVHKVHGD-VAVK-LAKPGKGDQLKMHQK---EARKHGLSLTCDYIVAIKGFVKCEEDTCPCGLLGIVMQYMENG----SLWD | .| ||||.|.|..|| |. |||| . |... .. ... |.. . ...|| ..... . . . .|| |.|.| .|. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIY------MVMEYCEGGLYVMDLF- FRIS--EWQPF--PDLWPLTNRMVYQISCGMHFLHSKNIIHRDLKLENVLVDGDLHV----KIADLGLA----TNLQTSSGDRCWGTDSHKPPEAFRTDL .|| . .| . . ...||| .|. ..||..|||||||.||.|.| . |. ||.| ||| . .. ..| || .|| | DYISTWRHGCFYFS--EWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFC-GTPWYMAPEVIR--- PNSTKVVTPKYDVYSFAMTLYELLTGIHPYSDR----------GFDMMKLLKVEAKQP--------------PCLQPVPVNAPKDLIEVMQECWSYEANE . . .|| |..|. .|||.|.| |.... ... . ... | . .... .|......... |. . .. --GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHF-HWTF-HNWSEECKDFIKWCLCKDPKK RPNFREIRDR--V ||....| . RPTAEQILQHPWF |
|||||||||
| Kinase | ANKK2.AA | MLK | 149-338 | 26 | 8.4e-36 | 121.72 | In-house | 85-291 (291) | Show / Hide |
Range on Protein: 149-338 Range on HMM: 85-291/291 Sequence Identity: 26% (57 aa) LGIVMQYMENGSLWDFRIS-EWQPF----------PDLWPLTNRMVYQISCGMHFLHSKN---IIHRDLKLENVLVD------GDLHVKIADLGLATNLQ ..|||.|.|.||| .. . . ... . .. .|.. |||.|||. ||||||| |.|.| .....||.| |... .. FCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWH TSSGD---RCWGTDSHKPPEAF--RTDLPNSTKVVTPKYDVYSFAMTLYELLTGIHPYSDRGFDMMKLLKVEAKQPPCLQPVPVNAPKDLIEVMQECWSY .. . || ||.. ..| |. ||.|... |.|.||. .||.. |. . .| .. |.| ..|. . . |..||. QMC-TNMMSNAGTYAWMAPEVIQQFRCEKYSEKC-----DVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGL--RPPIPSTCPEHWKKLMKQCWNQ EANERPNFREIRDRV ....||.||.| DPHKRPSFRQIVQHL |
|||||||||
| Kinase | ANKK2.AA | S_TKc | 73-339 | 23 | 3.2e-34 | 120.94 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 73-339 Range on HMM: 1-231/231 Sequence Identity: 23% (68 aa) ELEGCHLGGGSFGEVFKAVHKV-HGDVAVKLAKPGKGDQLKMHQKEARKHGLSLTCDYIVAIKGFVKCEEDTCPCGLLGIVMQYMEN--GSLWDFRISEW . ..| |.||.|.|..|| . ||.| | .. ..| . . ...|| .... . | .|| |... |.| |. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRG QP-----FPDLWPLTNRMVYQISCGMHFLHSKNIIHRDLKLENVLVDGDLHVKIADLGLATNLQTSSGDRCWGTDSHKPPEAFRTDLPNSTKVVTP-KYD . || . . ...||| |.. ..||..||||||| ||.|.| |.||.| |||. | . . || .|| . .. | | RHGLRFPFPE-H--ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---------GYGKCKCD VYSFAMTLYELLTGIHPYSDRGFDMMKLLKVEAKQPPCLQPVPVNAPKDLIEVMQECWSYEANERPNFREIRD--------RVK ..|. .|||.|.| |.. . |.|... ...... .. |. .. ..|| |. WWSCGCILYEMLCGYPPFP-QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
| Kinase | ANKK2.AA | TyrKc | 73-338 | 27 | 2.7e-32 | 114.52 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 73-338
Range on HMM: 1-280/280
Sequence Identity: 27% (82 aa)
ELEGCHLGGGSFGEVFKAVHKVHGDVAVKLAKPGKGDQLKMHQKEARKHGLSL--TCDYIVAIKGFVKCEEDTCPC---GLLGIVMQYMENGSLWDFRIS
| || | ||||.|.. | .|||| |... ... .||| .| . ||.. | . .. . | ||| ||..|.| |. .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMC-KLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLRK
EWQPFPDLWPLTNRMVYQISCGMHFLHSKNIIHRDLKLENVLVDGDLHVKIADLGLATNLQTS-------SGDRCWGTDSHK--------PPEAFRTDLP
.. . .||.||| .|||||.||||| |.||. ...|||.| ||. .. . | .... | .||..
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----
NSTKVVTPKYDVYSFAMTLYELLT-GIHPYSD------RGFDMMKLLKVEAKQPPCLQPVPVN----APKDLIEVMQECWSYEANERPNFREIRDRV
... |.| ||.|| ...|..| | ||.. .......| |. . | .|... ..|..|| .....||.|.||...
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
|
|||||||||
| Kinase | ANKK2.AA | TKL-Unique | 76-338 | 24 | 1.5e-29 | 101.45 | In-house | 2-290 (290) | Show / Hide |
Range on Protein: 76-338 Range on HMM: 2-290/290 Sequence Identity: 24% (74 aa) GCHLGGGSFGEVFKAVHKVHGDVAVKLAKP---GKGDQLKMHQKEARKHGLSLTCDYIVAIKGFVKCEEDTCPCGLLGIVMQYMENGSLWDFRI------ . .|.|..|.|.|.... .||.| .| . .. . .| . . || . |. | .. . . . ||| |.. ||| | WNKIGEGGYGQVYKGKWRGY-PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGY--CMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN ---SEWQPFPDLWPLTNRMVYQISCGMHFLHSKN--IIHRDLKLENVLVDGD-----LHVKIADLGLATNLQTSSGDRCW-----------GTDSHKPPE .. ... . . ..|. .|. ||..||... ||||||| |.||| . . .||.| ||.... ... |. .|| NNNNNNCKLN--MQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE AFRTDLPNSTKVVTPKYDVYSFAMTLYELLTGIH------PYSDRGFD-MMKLLKV--EAKQPPCLQPVPVNAPKDLIEVMQECWSYEANERPNFREIRD .| . . | |||||.. |.|..|. ||.. .. ..... | ..| |.| . ||.. . .|.|| . .||.| ||. VLRMNF----CQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRP----PIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIH RV | RL |
|||||||||
| Kinase | ANKK2.AA | LRRK | 176-340 | 27 | 7.1e-28 | 95.69 | In-house | 163-351 (351) | Show / Hide |
Range on Protein: 176-340 Range on HMM: 163-351/351 Sequence Identity: 27% (54 aa) WPLTNRMVYQISCGMHFLHSKN--IIHRDLKLENVLV---D---------GDLHVKIADLGLAT--NLQTSS-GDRCWGTDSHKPPEAFRTD--LPNSTK | |. . ..||. || .|||.| ||||||| .|.|. . . ..|||| |. . ... .| |. || | . ..| WMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEK VVTPKYDVYSFAMTLYELLTGI-HPYSDRG----FDMMKLLKV--EAKQPPCLQ---PVPVNAPKDLIEVMQECWSYEANERPNFREIRDRVKN | |.|||.| |.||||. ||. . . .| ... ...| . |. . .. . .|.||. . ..|| | .| .| . V-----DCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ |
|||||||||
| Kinase | ANKK2.AA | STE | 74-333 | 19 | 3.6e-26 | 89.47 | In-house | 1-350 (359) | Show / Hide |
Range on Protein: 74-333
Range on HMM: 1-350/359
Sequence Identity: 19% (71 aa)
LEG-CHLGGGSFGEVFKAVHKVHGD----------------VAVKLAKPGKG-----------------DQLKMHQKEARKHGLSLT-CDYIVAIKGFVK
.|| .| |.||.|.||... .. .|.| . . .... .|| . . . ...|| |
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF
CE------EDTCPCGLLGIVMQYMENGSLWDFRISEWQPFPDLW-----------PLTNRMVYQISCG-MHFLHSKNIIHRDLKLENVLVDGDLHVKIAD
| .|. | |.| ||..||| |. . . .. .| .. ....|| | ...|||..|||||.| |.|. ||..|
KEGHNHKNDDE-----LWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCD
LGLATNLQTS--------------SGD----RCWGTDSHKPPEAFRTDLPNST-KVVTPKYDVYSFAMTLYELLTGIHPYSD-RGFDMMKLLKVEA----
|....|. | ... . || . || . . . . | . | |..|. |. |..|| .|..| . .| . .
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQ
---------KQPPCLQP----------------VPVNAPKDLIEVMQECWSYEANERPNFRE
..|| |.. .| . ..... .. | .. |.||. .
QFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
|
|||||||||
| Kinase | ANKK2.AA | UTK | 79-233 | 28 | 3.7e-19 | 62.18 | In-house | 7-183 (296) | Show / Hide |
Range on Protein: 79-233 Range on HMM: 7-183/296 Sequence Identity: 28% (52 aa) LGGGSFGEVFKAVHK------VHGDVAVKLAKPGKGDQLKMH-----QKEAR--KHGLSLT-CDYIVAIKGFVKCEEDTCPCGLLGIVMQYMENGSLWDF || | ||||.|| . ||||| ..... .| .. .||| . . ... | . || . ||. |||||.| .. LGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP------WMIVTEYMENGDLRSY RISEWQPFP-DLWPLTNR----MVYQISCGMHFLHSKNIIHRDLKLENVLVDGD-------LHVKIADLG---LATNLQTSSGD . . .| . ||.. |...|..||..|||....|||| |.||. . . .||||.| .. ...| . . LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFH-F |
|||||||||
| Kinase | ANKK2.AA | RAF | 185-225 | 56 | 1.4e-17 | 53.29 | In-house | 111-151 (282) | Show / Hide |
Range on Protein: 185-225 Range on HMM: 111-151/282 Sequence Identity: 56% (23 aa) QISCGMHFLHSKNIIHRDLKLENVLVDGDLHVKIADLGLAT |.. || .||.||||||||| |.. . |. ||| | ||.| QVCQGMDYLHAKNIIHRDLKSNNIFLHEDMTVKIGDFGLMT |
|||||||||
| Kinase | ANKK2.AA | TK-Unique | 184-276 | 34 | 2e-17 | 56.78 | In-house | 138-234 (294) | Show / Hide |
Range on Protein: 184-276 Range on HMM: 138-234/294 Sequence Identity: 34% (35 aa) YQISCGMHFLHS--KNIIHRDLKLENVLVDGDLHVKIADLGLATNLQT---SSGDRCWGTDSHK--PPEAFRTDLPNSTKVV-TPKYDVYSFAMTLYELL .|| ||| .|.| |.|.|||| |||. .|. .||.|.|.|. ..| | . |. ... .||... . ... |.| ||.||. ...|.. WQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCY----HGMYHTTKSDVWSFGVLMWEIF T | T |
|||||||||
| Kinase | ANKK2.AA | Pkinase_Tyr | 182-224 | 55 | 2e-15 | 52.88 | Pfam | 116-158 (270) | Show / Hide |
Range on Protein: 182-224 Range on HMM: 116-158/270 Sequence Identity: 55% (24 aa) MVYQISCGMHFLHSKNIIHRDLKLENVLVDGDLHVKIADLGLA | .||..|| .|.|||.||||| |.||. ...|||.| ||| MCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA |
|||||||||
| Kinase | ANKK2.AA | RAF | 263-340 | 31 | 6.3e-12 | 34.66 | In-house | 203-282 (282) | Show / Hide |
Range on Protein: 263-340 Range on HMM: 203-282/282 Sequence Identity: 31% (25 aa) DVYSFAMTLYELLTGIHPY-SDRGFDMMKLLKVEAKQ-PPCLQPVPVNAPKDLIEVMQECWSYEANERPNFREIRDRVKN ||||| . .|||.|. || .. . . . | | | ..|| . . |..||... .||| |..| |.. DVYSFGIVMYELMTRHMPYGCHIWNRDQIIFMCGRGYLRPDLSKVRQDCPKAMHRLMEDCWKFQREERPLFQQILKRITV |
|||||||||
| Kinase | ANKK2.AA | Pkinase_Tyr | 263-338 | 29 | 1.8e-11 | 39.48 | Pfam | 196-270 (270) | Show / Hide |
Range on Protein: 263-338 Range on HMM: 196-270/270 Sequence Identity: 29% (23 aa) DVYSFAMTLYELLT-GIHP-YSDR-GFDMMKLLKVEAKQPPCLQPVPVNAPKDLIEVMQECWSYEANERPNFREIRDRV ||.|| ...|..| | | | . ........ . . || | |.|... ..|..|| |....|| |.||. . DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC----PENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
|||||||||
| Kinase | ANKK2.AA | TK-Unique | 309-338 | 36 | 2.1e-09 | 28.69 | In-house | 265-294 (294) | Show / Hide |
Range on Protein: 309-338 Range on HMM: 265-294/294 Sequence Identity: 36% (11 aa) APKDLIEVMQECWSYEANERPNFREIRDRV ..... ..|..||..|. |||.||.|..| CSHEMYNLMKSCWQWEPEERPSFRQIKHRL |
|||||||||
| Kinase | ANKK2.AA | UTK | 310-338 | 31 | 1.4e-08 | 25.5 | In-house | 268-296 (296) | Show / Hide |
Range on Protein: 310-338 Range on HMM: 268-296/296 Sequence Identity: 31% (9 aa) PKDLIEVMQECWSYEANERPNFREIRDRV | .. ..|..|| |. |||.|....... PHPVYRLMHRCWHYDPQERPDFEDLVQQM |
|||||||||
| Kinase | ANKK2.AA | Pkinase_Tyr | 76-164 | 30 | 1.1e-05 | 19.82 | Pfam | 4-97 (270) | Show / Hide |
Range on Protein: 76-164 Range on HMM: 4-97/270 Sequence Identity: 30% (30 aa) GCHLGGGSFGEVFKAVHK-----VHGDVAVKLAKPGKGDQ----LKMHQKEARKHGLSL-TCDYIVAIKGFVKCEEDTCPCGLLGIVMQYMENGSLWDF | || |.||||.|.. | . .|||| |.| .. .. . ||. .| .. || | . .... . ||| ||..|.| |. GKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMK-QLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLDY |
|||||||||
| Kinase | ANKK2.AA | RAF | 76-101 | 50 | 0.001051 | 7.55 | In-house | 4-27 (282) | Show / Hide |
Range on Protein: 76-101 Range on HMM: 4-27/282 Sequence Identity: 50% (13 aa) GCHLGGGSFGEVFKAVHKVHGDVAVK . | |||| |... . ||||||| MTRIGSGSFGTVYRG--HWHGDVAVK |
|||||||||
| Kinase | ANKK2.AA | MLK | 73-91 | 36 | 0.010003 | 5.44 | In-house | 1-19 (291) | Show / Hide |
Range on Protein: 73-91 Range on HMM: 1-19/291 Sequence Identity: 36% (7 aa) ELEGCHLGGGSFGEVFKAV .. ..| ||||.|.|.. IQFHEWIGSGSFGKVWKGR |
|||||||||
| Kinase | ANKK2.AA | LRRK | 73-90 | 31 | 0.032449 | 3.62 | In-house | 1-19 (351) | Show / Hide |
Range on Protein: 73-90 Range on HMM: 1-19/351 Sequence Identity: 31% (6 aa) ELEGCHLGGGSFG-EVFKA .. .| |.|| .|..| LKIEEQIGRGGFGTFVYRA |
|||||||||
| Kinase | ANKK2.AA | UTK | 263-277 | 40 | 0.137275 | 1.21 | In-house | 222-236 (296) | Show / Hide |
Range on Protein: 263-277 Range on HMM: 222-236/296 Sequence Identity: 40% (6 aa) DVYSFAMTLYELLTG ||.|| ...|..|. DVWSFGVVCWEIWTW |
|||||||||