ANKK3

Species: Sea Urchin
Alias: ANKK3, Spk367, SPU_008015
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TKL
Family: RIPK

Sequence

Name Sequence Type Origin Length Description Download
ANKK3.AA Protein None 1536 None Fasta, JSON
ANKK3.kin_dom Protein Kinase Domain None 187 None Fasta, JSON

Protein domain

Protein domains of ANKK3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Ank ANKK3.AA Ank 110-142 45 9.2e-11 43.07 Pfam 1-33 (33) Show / Hide
Range on Protein: 110-142
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

NGFTPLHAASQEGHIDVVEYLVGQGAQIDTCDS
.|||||| |.. ||..||..|...|| ..  | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 44-76 45 4.4e-10 40.62 Pfam 1-33 (33) Show / Hide
Range on Protein: 44-76
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

DDETPLHCASRNGHLDVVKYLIGQEAQVDYPTK
| .||||.|.|.||..|||.|... | |.  ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 77-109 36 1.4e-05 24.37 Pfam 1-33 (33) Show / Hide
Range on Protein: 77-109
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

NGTTALFLASNAGHRDLVEYLVGKGAQVEKGGK
.| |.| ||.  || . |..|...|| |    .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 11-43 36 0.000161 20.56 Pfam 1-33 (33) Show / Hide
Range on Protein: 11-43
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

DDDKALLGAALNGHLDVVKYLTGQGAQIETRDN
| . .|  |...||..|||.| ..|| .  .|.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 210-242 48 1.2e-10 42.71 Pfam 1-33 (33) Show / Hide
Range on Protein: 210-242
Range on HMM: 1-33/33
Sequence Identity: 48% (16 aa)

DDQTPLHGASRNGHLDVVKYLIGQGAQINKPTK
| .|||| |.|.||..|||.|...|| .|  ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 147-176 46 3.2e-08 33.93 Pfam 4-33 (33) Show / Hide
Range on Protein: 147-176
Range on HMM: 4-33/33
Sequence Identity: 46% (14 aa)

TPLHGASRNGHLDVVKYLIGQGAQIDKPTK
|||| |.|.||..|||.|...|| ..  ..
TPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 177-209 30 0.000342 19.38 Pfam 1-33 (33) Show / Hide
Range on Protein: 177-209
Range on HMM: 1-33/33
Sequence Identity: 30% (10 aa)

LGGTAILFASGEGHRDIVEYLVRQGAQIDTCDI
 | |.   |.  || ..|..|. .|| ..  | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 243-270 39 0.001128 17.51 Pfam 1-28 (33) Show / Hide
Range on Protein: 243-270
Range on HMM: 1-28/33
Sequence Identity: 39% (11 aa)

LGATALLFASNAGHRDVAEYLVGQGAQV
 | |.|  |.  || .|...|...|| |
DGFTPLHLACRCGHTEVVKMLLQHGADV

Ank ANKK3.AA Ank 441-473 39 3.9e-11 44.42 Pfam 1-33 (33) Show / Hide
Range on Protein: 441-473
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

HGQTPLHCSSCNGHLDVVKYLIGQGAQIDKPTK
.|.||||. ...||..|||.|...|| ..  ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 507-539 39 2.7e-10 41.41 Pfam 1-33 (33) Show / Hide
Range on Protein: 507-539
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

DDQTPLHCSSCYGHLDVVKYLIGQGAQIDKPTK
| .||||. ...||..|||.|...|| ..  ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 408-440 42 6.9e-10 39.91 Pfam 1-33 (33) Show / Hide
Range on Protein: 408-440
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

NGITPLHAASTQGHLDVVRYLVGQGAQIDTCDI
.| |||| |.  ||..||..|...|| ..  | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 309-341 39 2.9e-09 37.68 Pfam 1-33 (33) Show / Hide
Range on Protein: 309-341
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

YDETPLHCSSRNGHLDVVKYLIRQGAQIDKPTE
. .||||. .|.||..|||.|. .|| ..  . 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 870-902 48 3.7e-09 37.27 Pfam 1-33 (33) Show / Hide
Range on Protein: 870-902
Range on HMM: 1-33/33
Sequence Identity: 48% (16 aa)

NGFTPLLAASSNGHLDVVKYLVGQGAKVKEGDN
.|||||  |...||..|||.|...|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 936-968 48 3.7e-09 37.27 Pfam 1-33 (33) Show / Hide
Range on Protein: 936-968
Range on HMM: 1-33/33
Sequence Identity: 48% (16 aa)

NGFTPLLAASSNGHLDVVKYLVGQGAKVKEGDN
.|||||  |...||..|||.|...|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 771-803 45 6e-09 36.53 Pfam 1-33 (33) Show / Hide
Range on Protein: 771-803
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

NGFTPLHAASTKGHLDLVAYLVGRGAQVERGDN
.|||||| |. .||.. | .|...|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 903-935 45 9.3e-09 35.84 Pfam 1-33 (33) Show / Hide
Range on Protein: 903-935
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

NGFTPLHAASTKGRLDVVKYLVGQGAQVERGAN
.|||||| |. .|...|||.|...|| |    .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 540-572 39 1.6e-08 35.0 Pfam 1-33 (33) Show / Hide
Range on Protein: 540-572
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

LGATALHCSSRNGHLDVVKYLIGQGAQIANPTK
 | |.||. .|.||..|||.|...|| .   ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 1101-1133 45 2.7e-08 34.18 Pfam 1-33 (33) Show / Hide
Range on Protein: 1101-1133
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

NGFTPLLAASSNGHLDVVKYLVGQGAQVERGAN
.|||||  |...||..|||.|...|| |    .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 606-638 42 3.2e-08 33.93 Pfam 1-33 (33) Show / Hide
Range on Protein: 606-638
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

YGQTPLHFASQKGHLDVVEYLDGQGAQVKRGTN
.|.|||| |...||..||..| ..|| |   ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 969-1001 42 3.2e-08 33.91 Pfam 1-33 (33) Show / Hide
Range on Protein: 969-1001
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

NGFTPLHAASTKGRLDLVAYLVGRGAQVERGDN
.|||||| |. .|... | .|...|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 705-737 42 4.2e-08 33.48 Pfam 1-33 (33) Show / Hide
Range on Protein: 705-737
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

NGFTPLHAASTKGHLDLVAYLVGRGAQVERSSN
.|||||| |. .||.. | .|...|| |    .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 1002-1034 42 8.6e-08 32.37 Pfam 1-33 (33) Show / Hide
Range on Protein: 1002-1034
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

TGWTPLLSASQGGHLDVVQYLLGQGAQVKRGTN
 |.|||  |.. ||..||..||..|| |   ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 1035-1067 39 2.6e-07 30.63 Pfam 1-33 (33) Show / Hide
Range on Protein: 1035-1067
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

NGSTPLQVASRDGQLDVVQYLVGQGAQVERGNN
.| ||| .|.| |...||..|...|| |   ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 837-869 42 3.5e-07 30.15 Pfam 1-33 (33) Show / Hide
Range on Protein: 837-869
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

DGLTPLLAASSNGYLDVVKYLVGQGAQVERGAN
|| |||  |...|...|||.|...|| |    .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 1068-1100 42 3.5e-07 30.15 Pfam 1-33 (33) Show / Hide
Range on Protein: 1068-1100
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

DGLTPLLAASSNGYLDVVKYLVGQGAQVERGAN
|| |||  |...|...|||.|...|| |    .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 639-671 36 4e-07 29.95 Pfam 1-33 (33) Show / Hide
Range on Protein: 639-671
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

NGSTPLQVASLDGQLDVVQYLVRQGAQVERSNN
.| ||| .|.. |...||..|. .|| |   ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 573-605 36 4.9e-07 29.64 Pfam 1-33 (33) Show / Hide
Range on Protein: 573-605
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

LCITALHLASDAGHRDIVEYLVRQGAQIDTCDI
   |.||||.  || ..|..|. .|| ..  | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 738-770 45 6.2e-07 29.27 Pfam 1-33 (33) Show / Hide
Range on Protein: 738-770
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

YGLTSLLAASRHGHLDVVKYLVGQGAKVKEGDN
.| | |  |.|.||..|||.|...|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 276-308 33 9.3e-07 28.64 Pfam 1-33 (33) Show / Hide
Range on Protein: 276-308
Range on HMM: 1-33/33
Sequence Identity: 33% (11 aa)

NGLTPVLTASEKGHLDVVEYLVGQGAQIETLNK
.| ||   |...||..||..|...|| .   ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 375-407 42 1e-06 28.07 Pfam 1-33 (33) Show / Hide
Range on Protein: 375-407
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

SGLTPLIAASEKGHIDVVKYLFGQGAKVKKGNN
 | |||  |...||..|||.| ..|| |   ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 804-836 39 1e-06 28.08 Pfam 1-33 (33) Show / Hide
Range on Protein: 804-836
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

TGWTPLLSASQGGHLDVVQYLVVQGAQVERGNN
 |.|||  |.. ||..||..|. .|| |   ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 672-704 48 3e-06 26.57 Pfam 1-33 (33) Show / Hide
Range on Protein: 672-704
Range on HMM: 1-33/33
Sequence Identity: 48% (16 aa)

DGTTSLLAASRHGHLDVVKYLAGQGAKVKEGDN
|| | |  |.|.||..|||.| ..|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 474-506 30 0.000342 19.38 Pfam 1-33 (33) Show / Hide
Range on Protein: 474-506
Range on HMM: 1-33/33
Sequence Identity: 30% (10 aa)

LGGTAILFASGEGHRDIVEYLVRQGAQIDTCDI
 | |.   |.  || ..|..|. .|| ..  | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 1134-1159 38 0.000731 18.19 Pfam 1-26 (33) Show / Hide
Range on Protein: 1134-1159
Range on HMM: 1-26/33
Sequence Identity: 38% (10 aa)

NGLTPLLAASSNGHLDVAQYLTSKQA
.| |||  |...||..|...| .. |
DGFTPLHLACRCGHTEVVKMLLQHGA

Ank ANKK3.AA Ank 342-374 30 0.006695 14.72 Pfam 1-33 (33) Show / Hide
Range on Protein: 342-374
Range on HMM: 1-33/33
Sequence Identity: 30% (10 aa)

LGITALVFGSDAGHRNIVEYLVGQGAQVERGSN
 | |.|   .  || ..|..|...|| |    .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 1235-1260 38 0.000731 18.19 Pfam 1-26 (33) Show / Hide
Range on Protein: 1235-1260
Range on HMM: 1-26/33
Sequence Identity: 38% (10 aa)

NGLTPLLAASSNGHLDVAQYLTSKQA
.| |||  |...||..|...| .. |
DGFTPLHLACRCGHTEVVKMLLQHGA

Ank ANKK3.AA Ank 1202-1234 33 0.02575 12.61 Pfam 1-33 (33) Show / Hide
Range on Protein: 1202-1234
Range on HMM: 1-33/33
Sequence Identity: 33% (11 aa)

LGAMALLFASGVGHRDVVEYLVGQGAQVERGAN
 |  .|  |.  || .||..|...|| |    .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank ANKK3.AA Ank 1185-1201 29 0.395786 8.33 Pfam 17-33 (33) Show / Hide
Range on Protein: 1185-1201
Range on HMM: 17-33/33
Sequence Identity: 29% (5 aa)

CVKFLIGQGAQIDKPTK
.||.|...|| ..  ..
VVKMLLQHGADVNAQDD

Kinase ANKK3.AA RIPK 1322-1508 53 8.60000000001e-125 420.88 In-house 1-212 (290) Show / Hide
Range on Protein: 1322-1508
Range on HMM: 1-212/290
Sequence Identity: 53% (114 aa)

LGGGSFGEVYKATHAVHGDVAVKLAKPGKE------RQVEMYQKEARKHENSLICEHIVPIKGFVECEDDACNCGLIGIVMKYMENGSLWDFRTTKW--Q
.|||.||||.||.|...||...|..||.|.      .|..|||||..||...|.|||||||.||..||...|.|.|.||||.||||||||.|..|||  |
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

QHPDLLPLTNRMVYEMSSGMQFLHSKD--IIHRDLKLENVLVDGDLHVKIADLGLATNLQTS--FGDRC-------------CGTHSHKPPEAFRTDIPN
.|||..||..||..|.|.||..|||..  |||||||.||.|||...||||||.||||....|  ..|||             .||.|..|||.|||| ..
HHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKK

SIMIGTPKYDVY
.|.. |||||||
PIKVVTPKYDVY

Kinase ANKK3.AA TKL 1322-1508 22 1.8e-53 183.98 In-house 1-273 (364) Show / Hide
Range on Protein: 1322-1508
Range on HMM: 1-273/364
Sequence Identity: 22% (63 aa)

LGGGSFGEVYKATHAVHG---------DVAVKLAKPG--------------------------KERQVEMYQKEARKHENSLICEHIVPIKGFVECEDDA
.| |.||||||...  .|         |||||  |                            . .. .   .|  .. ..| ...||...|.. |... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

C-------NCGLIGIVMKYMENGSLWDFRTTKWQQHPDLLPLTNRMVYEMSSGMQFLHSKD--------IIHRDLKLENVLVDGDLH-------------
|       ..| ..||| |...|||... .         .... |.......||..|||..        ||||||| .|.||| ...             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-VKIADLGLATNLQTSFGDRC---------------------CGTHSHKPPEAFRTDIPNSI----------MIGTPKYDVY
 .||.|.||......|... .                     |||  . .||..| .....              ..| |||
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVY

Kinase ANKK3.AA Pkinase 1322-1479 29 1.9e-25 91.09 Pfam 7-173 (293) Show / Hide
Range on Protein: 1322-1479
Range on HMM: 7-173/293
Sequence Identity: 29% (53 aa)

LGGGSFGEVYKATHAVHGD-VAVKLAKPGKERQVEMYQK----EARKHENSLICEHIVPIKGFVECEDDACNCGLIGIVMKYMENG----SLWDFRTTKW
.| ||||.|||..|   |. ||||  |  .|.  . ...    |.. . .   ...|| .....| .|. .      .|| |.|.|    .|.|. .|  
IGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIY------MVMEYCEGGLYVMDLFDYIST--

QQHPDL---LPLTNRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHV----KIADLGLA----TNLQTSFGDRCC
..|  .        ...|.. .|....||. |||||||.||.|.| . |.    ||.| |||    .  .. . ..|.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCG

Kinase ANKK3.AA STE 1317-1481 20 1.6e-24 83.58 In-house 1-226 (359) Show / Hide
Range on Protein: 1317-1481
Range on HMM: 1-226/359
Sequence Identity: 20% (48 aa)

LKG-CHLGGGSFGEVYKATHAVHGD----------------VAVKLAKPGKE-----------------RQVEMYQKEARKHENSLI-CEHIVPIKGFVE
..|   .| |.||.|||| .   ..                .|.|  .  ..                  ... ..|| . . ..   ...||   |  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

CEDD-ACNCGLIGIVMKYMENGSLWDFRTTKWQQHPDL-----------LPLTNRMVYEMSSG-MQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLAT
 |..   |.. . |.| ||..||| |.  .|.    .|            ..  .....   | ...|||. |||||.|  |.|.     ||..| |...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

NLQTS------------------FGDRCCGT
.|. |                    . ..||
QLTDSMANIQSNNIIDCIETMQQKRNTFVGT

Kinase ANKK3.AA AGC 1428-1482 20 3.2e-24 58.15 In-house 154-271 (395) Show / Hide
Range on Protein: 1428-1482
Range on HMM: 154-271/395
Sequence Identity: 20% (24 aa)

E-------MSSGMQFLHS-KDIIHRD-LKLENVLVDGDLHVKIADLGLATNLQTSFGD------------------------------------------
|       . .....||| ..||||| ||.||.| | | |.|..| ||.. . .. ..                                          
EMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDD

----------RCCG--TH
            ||  |.
TTRKKRDRTWTFCGPCTP

Kinase ANKK3.AA Ciliate-E2-Unclassified 1322-1491 20 1.3e-21 71.78 In-house 7-239 (352) Show / Hide
Range on Protein: 1322-1491
Range on HMM: 7-239/352
Sequence Identity: 20% (49 aa)

LGGGSFGEVYKATH------------AVHGDVAVKLAKPGKERQVEMYQKEARKHENSLI------------CEHIVPIKGFVECEDDACNCGLIGIVMK
.| |.||.|||. |             .. ....|. .  .|   || . . .|. ..              . |.. .| | . .|. .    | ||| 
IGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN----IYIVME

YMENGSLWDFRTTKWQ--------------QHPDLLPLTN-----RMVYEMSSGMQFLHSKD-IIHRDLKLENVLVDGDL---HVKIADLGLAT------
|.|.|.||.. . ...              ..      .      .. ..  .| ..||.|  |||||.|.||.|.| .    ..||.|.|..       
YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNN

-----------NLQTSFGDRCCGTHSHK----PPEAFR
           ...    . .||| . .    .|| ..
NCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQ

Kinase ANKK3.AA Ciliate-E2 1322-1491 18 2.4e-21 70.0 In-house 7-260 (365) Show / Hide
Range on Protein: 1322-1491
Range on HMM: 7-260/365
Sequence Identity: 18% (48 aa)

LGGGSFGEVYKATH-AVHGDVA-----VKLAKPG--------KERQVEMYQK---EARKHENSLI--------------------CEHIVPIKGFVECED
.| |.|| |||...  |  ..|      |. ...        |.  .....|   |. | |....                    . .|. .. . . .|
IGQGNFGSVYKCKVWKVQKQFAIKIIDQKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKD

DACNCGLIGIVMKYMENGSLWDFRTTKWQQHPDLLP--------LTNRMVYEMSS---------------GMQFLHSKD-IIHRDLKLENVLVDGDLHVK
| .    | .|| | . |.|.|.   ......  ..           .. ..  .               ....||||  |||||.|.||.|.     .|
DNN----IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IK

IADLGLAT---------------NLQTSFG-------------------DRCCGTHSHKPPEAFR
|.|.||..               .. .  .                   ...|||   ..|| ..
IIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILN

Kinase ANKK3.AA TK 1322-1467 19 6.5e-21 66.16 In-house 7-298 (486) Show / Hide
Range on Protein: 1322-1467
Range on HMM: 7-298/486
Sequence Identity: 19% (56 aa)

LGGGSFG---EVYKATHAVHG--------------------------DVAVKLAKPGKERQVEMYQK-----------------EARKHENSLI-CEHIV
|| | ||   ||||..   ..                          .||||  |.| . . |. .                  |. .  .||  ...||
LGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIV

PIKG-FVECEDDACNC-----GLIGIVMKYMENGS--------LWDFRTT------------------------------------------------KW
 . |  .. |   |       . . ||| ||..|.        |.. | .                                                 .
RLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIK

QQHPDLLP-----------------LTNRMVYEMS----SGMQFLHSKDI------IHRDLKLENVLVDGDLH-----------VKIADLGLA
.. |.|                   || .    |.    .||..|||| .      .||||   |.||. ...           .|||| ||.
DHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

Kinase ANKK3.AA MLK 1316-1490 25 5.1e-20 66.23 In-house 1-205 (291) Show / Hide
Range on Protein: 1316-1490
Range on HMM: 1-205/291
Sequence Identity: 25% (55 aa)

KLKGCHLGGGSFGEVYKATHAVHGD-----VAVKLAKPGK---------ERQVEMYQKEARK--HENSLICEHIVPIKGFVECE-DDACNCGLIGIVMKY
 .   ..| ||||.|.|..     |     |||| ..  .          ...||  ...|.  |.|  .|  |....|   ..  . |      ||| |
IQFHEWIGSGSFGKVWKGRWRNK-DIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPC--IIQFYGVCLQPPCHFC------IVMEY

MENGSLWDFR---TTKWQQ--HPDL------LPLTNRMVYEMSSGMQFLHSKD---IIHRDLKLENVLVD------GDLHVKIADLGLATNLQTSFGD--
.|.||| ..    ..||    |..       . . ..  . ...||..|||..   |||||||  |.|.|      .....||.| |... ....  .  
CEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNM

-RCCGTHSHKPPEAF
   .||     ||..
MSNAGTYAWMAPEVI

Kinase ANKK3.AA CAMK 1424-1481 22 1.1e-18 56.19 In-house 183-282 (425) Show / Hide
Range on Protein: 1424-1481
Range on HMM: 183-282/425
Sequence Identity: 22% (22 aa)

RMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGD-----------------LHVKIADLGLATNLQTSFGDR-------------------------CCGT
|..  . |.....||..|.|||||.||.|.| .                   .||.| |.|. .. . ...                         .|||
RYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGT





Kinase ANKK3.AA S_TKc 1316-1535 23 6.3e-15 42.02 SMART 1-220 (231) Show / Hide
Range on Protein: 1316-1535
Range on HMM: 1-220/231
Sequence Identity: 23% (58 aa)

KLKGCHLGGGSFGEVYKATHAV-HGDVAVKLAKPGKERQVEMYQKEARKHENSLICEHIVPIKGFVECEDDACNCGLIGIVMKYMEN--GSLWDFRTTKW
  .. ..| |.||.|||..|   .  ||.|  |       |. ..| . ...   ...|| .... .        . . .|| |...  |.| |.   . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRG

QQ---HPDLLPLTNRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLATNLQTSFGDRCCGTHSHKPPEAFRTDIPNSI-----------
 .   .|     . ...|.. ......||. ||||||| ||.|.|   |.||.| |||. |     . .|||    .|| .    . .            
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCI

----MIGTP----KYDVYRKASEKDTHNEAFNVINIFFGSDVK-------LA
    . | |     . ...|        || . |.  .  | .       |.
LYEMLCGYPPFPQMQMMFKKIG----SPEAKDFIRKCLQKDPEKRPTAEALQ

Kinase ANKK3.AA Src 1394-1467 41 9.6e-15 46.48 In-house 71-144 (255) Show / Hide
Range on Protein: 1394-1467
Range on HMM: 71-144/255
Sequence Identity: 41% (31 aa)

IVMKYMENGSLWDFRT-TKWQQHPDLLPLTNRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLA
||  ||..||| |.   ..  .|  |  |   |    ..||..| |. .|||||   ||||. .. .|.|| |||
IVTEYMSHGSLLDYLKKDGEGRHLHLPQLID-MAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLA

Kinase ANKK3.AA Pkinase_Tyr 1370-1467 35 1.4e-13 46.67 Pfam 63-158 (270) Show / Hide
Range on Protein: 1370-1467
Range on HMM: 63-158/270
Sequence Identity: 35% (35 aa)

CEHIVPIKGFVECEDDACNCGLIGIVMKYMENGSLWDFRTTK--WQQHPDLLPLTNRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLA
...||   | . ....      | ||| ||..|.| |.  ..  ..|....  | . | .. ..||..|.|| .|||||   |.||. ...|||.| |||
HPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQ-MCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA





Kinase ANKK3.AA TyrKc 1316-1536 21 7e-12 -30.58 SMART 1-280 (280) Show / Hide
Range on Protein: 1316-1536
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

KLKGCHLGGGSFGEVYKATHAVHGDVAVKLAKPGKERQVEMYQKEARKHENSL--ICEHIVPIKGFVECEDDACNC---GLIGIVMKYMENGSLWDFRTT
  .|  || | ||||||.|     .||||  |...   .|.  .|||   . |    ..|| . |   | ..  |    . . ||| ||..|.| |.   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCK-LGGHHPNIVRLYGV--CTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KWQQHPDLLPLTNRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLATNLQTS-----FGDRCCGTH--SHK--------PPEAFRTD--
.  .    ..    . .  ..||..|||| .|||||   |.||. ...|||.| ||. ..         .|    .   . |        .||....   
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

-------------------------------IPNSIMIGTPKYDVYRKASEKD-------THNEAFNVINIFFGS---------DVKLAA
                               ..|. .|   |   ...  . |        . | ....               ...   
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase ANKK3.AA Src 1322-1361 42 2e-06 17.88 In-house 7-45 (255) Show / Hide
Range on Protein: 1322-1361
Range on HMM: 7-45/255
Sequence Identity: 42% (17 aa)

LGGGSFGEVYKATHAVHGDVAVKLAKPGKERQVEMYQKEA
|| | ||||....   . .||||  |||   ..|....||
LGQGQFGEVWMGYWNGNTKVAVKTLKPGT-MSPEAFLQEA

Kinase ANKK3.AA CAMK 1321-1344 29 2.1e-05 12.58 In-house 1-37 (425) Show / Hide
Range on Protein: 1321-1344
Range on HMM: 1-37/425
Sequence Identity: 29% (11 aa)

HLGGGSFGEVYKATHAVHGD-------------VAVK
 || ||||.|....|   .              ||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIK

Kinase ANKK3.AA Pkinase_Tyr 1318-1362 35 0.000204 15.58 Pfam 3-55 (270) Show / Hide
Range on Protein: 1318-1362
Range on HMM: 3-55/270
Sequence Identity: 35% (19 aa)

KGCHLGGGSFGEVYKATHA-----VHGDVAVKLAKPGKERQ----VEMYQKEAR
.|  || |.||||||.|        . .||||  |.|   .     .. . ||.
FGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAK