Gene ank2 (Sea Urchin)

ank2

Species: Sea Urchin
Alias: SPU_019053, ank2, Spk320
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TKL
Family: RIPK

Sequence

Name Sequence Type Origin Length Description Download
ank2.AA Protein None 776 None Fasta, JSON
ank2.kin_dom Protein Kinase Domain None 179 None Fasta, JSON

Protein domain

Protein domains of ank2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Ank ank2.AA Ank 44-76 42 1.2e-10 42.62 Pfam 1-33 (33) Show / Hide 
Range on Protein: 44-76
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

NGFTPLHAASQDGHLDVVEYLVGQGAHIDKPNE
.|||||| |.. ||..||..|...|| ..  . 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 110-142 39 1.4e-10 42.38 Pfam 1-33 (33) Show / Hide 
Range on Protein: 110-142
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

NGLTPLHAASQKGHLDVVEYLVGQGAQIETRNN
.| |||| |...||..||..|...|| .  ...
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 143-175 39 5e-10 40.43 Pfam 1-33 (33) Show / Hide 
Range on Protein: 143-175
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

EDSTPLHYASHNGHLDVVKCLIGQGAQIDKPNE
.  ||||.|...||..|||.|...|| ..  . 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 77-109 45 3.6e-07 30.11 Pfam 1-33 (33) Show / Hide 
Range on Protein: 77-109
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

IGTTALILASDAGHLDVVQYLVSHGAQVERGDN
 | |.| ||.  ||..||..|..||| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 176-208 36 8e-06 25.29 Pfam 1-33 (33) Show / Hide 
Range on Protein: 176-208
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

FGATALHSGSAAGHRDLVEYLVGQGAQVEKCDN
 | |.||  .  || . |..|...|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 15-43 27 0.296957 8.78 Pfam 5-33 (33) Show / Hide 
Range on Protein: 15-43
Range on HMM: 5-33/33
Sequence Identity: 27% (8 aa)

ALLRAALNGCFEMVVYLVGQGAQIEKGGE
.|  |...|. |.| .|...|| .     
PLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 210-242 42 1.6e-09 38.62 Pfam 1-33 (33) Show / Hide 
Range on Protein: 210-242
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

NGMTPLHAASQKGHLDVVEYLVGQGAQVEKGGK
.|.|||| |...||..||..|...|| |    .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 243-270 50 2.3e-09 38.02 Pfam 1-28 (33) Show / Hide 
Range on Protein: 243-270
Range on HMM: 1-28/33
Sequence Identity: 50% (14 aa)

NGFTPLHVASQEGHLDVVEYLVGQGAQI
.||||||.|.. ||..||..|...|| .
DGFTPLHLACRCGHTEVVKMLLQHGADV
Ank ank2.AA Ank 277-309 36 2.9e-08 34.09 Pfam 1-33 (33) Show / Hide 
Range on Protein: 277-309
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

YDETPLHCSSCNGHLDVVKYLIGQEAQVDYPNK
. .||||. ...||..|||.|... | |.  ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 310-342 36 6.4e-07 29.21 Pfam 1-33 (33) Show / Hide 
Range on Protein: 310-342
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

NGITALFFASNAGHRDLVEYLVGQGAKVEKCDN
.| |.|  |.  || . |..|...|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 377-409 48 1.1e-11 46.41 Pfam 1-33 (33) Show / Hide 
Range on Protein: 377-409
Range on HMM: 1-33/33
Sequence Identity: 48% (16 aa)

DGDTPLHCASKKGHLDVVEYLVRQGAHVEKCDN
||.||||.|...||..||..|. .|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 344-376 45 2.9e-10 41.27 Pfam 1-33 (33) Show / Hide 
Range on Protein: 344-376
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

YGMTPLHAASQKGHLDVVEYLVGQGAQVEKGDN
.|.|||| |...||..||..|...|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 477-509 42 3.2e-11 44.72 Pfam 1-33 (33) Show / Hide 
Range on Protein: 477-509
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

NGMTPLHYASKTGHLDVVEYLVGQGAQIDTCDI
.|.||||.|.. ||..||..|...|| ..  | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 444-476 42 9e-09 35.89 Pfam 1-33 (33) Show / Hide 
Range on Protein: 444-476
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

KGDTPLIFASCNGHLDVVQYLVGQGAQVEKGDN
 |.|||  |...||..||..|...|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 411-443 42 2.2e-07 30.89 Pfam 1-33 (33) Show / Hide 
Range on Protein: 411-443
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

DGMTPLNAASQKGHLDVVEYLVGQRAQVERGDN
||.|||  |...||..||..|... | |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ank2.AA Ank 510-530 52 0.00021 20.14 Pfam 1-21 (33) Show / Hide 
Range on Protein: 510-530
Range on HMM: 1-21/33
Sequence Identity: 52% (11 aa)

DGQTPLYFASHNGHLDAVKFL
||.|||  |...||.. ||.|
DGFTPLHLACRCGHTEVVKML
Kinase ank2.AA RIPK 589-775 53 6.5e-125 421.29 In-house 1-212 (290) Show / Hide 
Range on Protein: 589-775
Range on HMM: 1-212/290
Sequence Identity: 53% (114 aa)

LGGGSFGEVYKATHTVHDDVAVKLAKPGKE------GQVVMYQKEARKHENSLICEHIVPIKGFVECEDDACNCGLIGIVMKYMENGSLWDFRTTKW--L
.|||.||||.||.| .. |...|..||.|.       |..|||||..||...|.|||||||.||..||...|.|.|.||||.||||||||.|..|||  .
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

QHPDLLPLINRMVYEMSSGMQFLHSKD--IIHRDLKLENVLVDGDLHVKIADLGLATNLQTS--FGDRC-------------WGTDSHKPPEAFRTDLPN
.|||..|| .||..|.|.||..|||..  |||||||.||.|||...||||||.||||....|  ..|||             |||.|..|||.||||...
HHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKK

STKIVTPKYDVY
..|.||||||||
PIKVVTPKYDVY
Kinase ank2.AA TKL 589-775 21 7.8e-53 181.85 In-house 1-273 (364) Show / Hide 
Range on Protein: 589-775
Range on HMM: 1-273/364
Sequence Identity: 21% (62 aa)

LGGGSFGEVYKATHTVHD---------DVAVKLAKPGKEG--------------------------QVVMYQKEARKHENSLICEHIVPIKGFVECEDDA
.| |.||||||...  ..         |||||  |   .                           .     .|  .. ..| ...||...|.. |... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

C-------NCGLIGIVMKYMENGSLWDFRTTKWLQHPDLLPLINRMVYEMSSGMQFLHSKD--------IIHRDLKLENVLVDGDLH-------------
|       ..| ..||| |...|||... .         .... |.......||..|||..        ||||||| .|.||| ...             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-VKIADLGLATNLQTSFGDRCW---------------------GTDSHKPPEAFRTDLPNSTK----------IVTPKYDVY
 .||.|.||......|... ..                     ||  . .||..| ..... |            ..| |||
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVY
Kinase ank2.AA STE 584-740 23 1.1e-24 84.13 In-house 1-200 (359) Show / Hide 
Range on Protein: 584-740
Range on HMM: 1-200/359
Sequence Identity: 23% (48 aa)

LEG-CHLGGGSFGEVYKATHT----------------VHDDVAVKLAKPGKEG-----------------QVVMYQKEARKHENSLI-CEHIVPIKGFVE
.||   .| |.||.|||| .                  .. .|.|  .  ..                  ..  ..|| . . ..   ...||   |  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

CEDD-ACNCGLIGIVMKYMENGSLWDFRTTKWLQHPDL-----------LPLINRMVYEMSSG-MQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLAT
 |..   |.. . |.| ||..||| |.  .|.    .|            ..| .....   | ...|||. |||||.|  |.|.     ||..| |...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

NLQTS
.|. |
QLTDS
Kinase ank2.AA Pkinase 589-745 27 2.1e-23 83.84 Pfam 7-172 (293) Show / Hide 
Range on Protein: 589-745
Range on HMM: 7-172/293
Sequence Identity: 27% (50 aa)

LGGGSFGEVYKATHTVHDD-VAVKLAKPGKEGQVVMYQK----EARKHENSLICEHIVPIKGFVECEDDACNCGLIGIVMKYMENG----SLWDFRTTKW
.| ||||.|||..|    . ||||  |  .|   . ...    |.. . .   ...|| .....| .|. .      .|| |.|.|    .|.      .
IGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIY------MVMEYCEGGLYVMDLF-----DY

LQ---HPDL---LPLINRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHV----KIADLGLA----TNLQTSFGDRC
..   |  .      . ...|.. .|....||. |||||||.||.|.| . |.    ||.| |||    .  .. . ..|
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFC
Kinase ank2.AA MLK 583-740 25 2e-21 71.14 In-house 1-186 (291) Show / Hide 
Range on Protein: 583-740
Range on HMM: 1-186/291
Sequence Identity: 25% (50 aa)

KLEGCHLGGGSFGEVYKATHTVHD----DVAVKLAKPGKEGQVVM-------YQKEAR-----KHENSLICEHIVPIKGFVECE-DDACNCGLIGIVMKY
 ..  ..| ||||.|.|..    |     |||| ..  ..  ..         ..|.|     .|.|  .|  |....|   ..  . |      ||| |
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPC--IIQFYGVCLQPPCHFC------IVMEY

MENGSLWDFR---TTKWLQ--HPDL------LPLINRMVYEMSSGMQFLHSKD---IIHRDLKLENVLVD------GDLHVKIADLGLATNLQTS
.|.||| ..    ..||    |..       . ....  . ...||..|||..   |||||||  |.|.|      .....||.| |... ....
CEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQM
Kinase ank2.AA TK 589-734 18 1e-19 62.11 In-house 7-298 (486) Show / Hide 
Range on Protein: 589-734
Range on HMM: 7-298/486
Sequence Identity: 18% (54 aa)

LGGGSFG---EVYKATHTVHD--------------------------DVAVKLAKPGKEGQVVMYQK-----------------EARKHENSLI-CEHIV
|| | ||   ||||..   ..                          .||||  |.| . .  . .                  |. .  .||  ...||
LGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIV

PIKG-FVECEDDACNC-----GLIGIVMKYMENGS--------LW-------------------------------------------------------
 . |  .. |   |       . . ||| ||..|.        |.                                                       
RLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIK

----DFRTTKWLQ-----------HPDLLPLINRMVYEMSSGMQFLHSKDI------IHRDLKLENVLVDGDLH-----------VKIADLGLA
    ...|.  ||           ....  |.  | .  ..||..|||| .      .||||   |.||. ...           .|||| ||.
DHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL--MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS
Kinase ank2.AA Ciliate-E2 589-740 21 1e-18 60.83 In-house 7-209 (365) Show / Hide 
Range on Protein: 589-740
Range on HMM: 7-209/365
Sequence Identity: 21% (45 aa)

LGGGSFGEVYKATH-TVHDDVAVKLAKPGK--------------EGQVVM--YQKEARKHENSLI--------------------CEHIVPIKGFVECED
.| |.|| |||...  |  ..| |. .  |                  .|  .|.|. | |....                    . .|. .. . . .|
IGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKD

DACNCGLIGIVMKYMENGSLWDFRTTKWLQHPDLLP--------LINRMVYEMSS---------------GMQFLHSKD-IIHRDLKLENVLVDGDLHVK
| .    | .|| | . |.|.|.   ......  ..         | .. ..  .               ....||||  |||||.|.||.|.     .|
DNN----IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IK

IADLGLATNLQTS
|.|.||.......
IIDFGLSKKYDDD
Kinase ank2.AA Ciliate-E2-Unclassified 589-739 22 6.5e-18 58.74 In-house 7-199 (352) Show / Hide 
Range on Protein: 589-739
Range on HMM: 7-199/352
Sequence Identity: 22% (44 aa)

LGGGSFGEVYKATH------------TVHDDVAVKLAKPGKEGQVVMYQKEARKHENSLI------------CEHIVPIKGFVECEDDACNCGLIGIVMK
.| |.||.|||. |             .. ....|. .  .|    | . . .|. ..              . |.. .| | . .|. .    | ||| 
IGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN----IYIVME

YMENGSLWDFRTTKWL--------------QHPDLLPLIN-----RMVYEMSSGMQFLHSKD-IIHRDLKLENVLVDGDL---HVKIADLGLATNLQT
|.|.|.||.. . ..               ..      .      .. ..  .| ..||.|  |||||.|.||.|.| .    ..||.|.|.. ..|.
YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ
Kinase ank2.AA CAMK 691-742 21 2.1e-17 51.96 In-house 183-281 (425) Show / Hide 
Range on Protein: 691-742
Range on HMM: 183-281/425
Sequence Identity: 21% (21 aa)

RMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGD-----------------LHVKIADLGLATN------------------------------LQTSFG
|..  . |.....||..|.|||||.||.|.| .                   .||.| |.|.                               ..|..|
RYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCG
Kinase ank2.AA Src 661-734 42 1.1e-15 49.69 In-house 71-144 (255) Show / Hide 
Range on Protein: 661-734
Range on HMM: 71-144/255
Sequence Identity: 42% (32 aa)

IVMKYMENGSLWDFRT-TKWLQHPDLLPLINRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLA
||  ||..||| |.   ..  .|  |  ||  |    ..||..| |. .|||||   ||||. .. .|.|| |||
IVTEYMSHGSLLDYLKKDGEGRHLHLPQLID-MAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLA
Kinase ank2.AA LISK 697-734 45 1.2e-15 47.11 In-house 111-152 (296) Show / Hide 
Range on Protein: 697-734
Range on HMM: 111-152/296
Sequence Identity: 45% (19 aa)

SSGMQFLHSKDIIHRDLKLENVLVD----GDLHVKIADLGLA
..|| .|||..|||||||  |.||.    ..  .|..|.|.|
ACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFA
Kinase ank2.AA Pkinase_Tyr 637-734 35 7.6e-14 47.51 Pfam 63-158 (270) Show / Hide 
Range on Protein: 637-734
Range on HMM: 63-158/270
Sequence Identity: 35% (35 aa)

CEHIVPIKGFVECEDDACNCGLIGIVMKYMENGSLWDFRTTK--WLQHPDLLPLINRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLA
...||   | . ....      | ||| ||..|.| |.  ..  . |....  |.. | .. ..||..|.|| .|||||   |.||. ...|||.| |||
HPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQ-MCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase ank2.AA S_TKc 583-773 20 1.4e-11 -7.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 583-773
Range on HMM: 1-231/231
Sequence Identity: 20% (52 aa)

KLEGCHLGGGSFGEVYKATHTV-HDDVAVKLAKPGKEGQVVMYQKEARKHENSLICEHIVPIKGFVECEDDACNCGLIGIVMKYMEN--GSLWDFRTTKW
   . ..| |.||.|||..|.  .  ||.|  |        . ..| . ...   ...|| .... .        . . .|| |...  |.| |.   . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRG

LQ---HPDLLPLINRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLATNLQTSF--------------GD-RC----------------
 .   .|     . ...|.. ......||. ||||||| ||.|.|   |.||.| |||. | |.|              |  .|                
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-TTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGY

--WGTDSHK------PPEAF----------RTDLPNSTKIVT-------PKYD
  .  . ..      .|||            .. |   .. .         . 
PPFP-QMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase ank2.AA TyrKc 583-768 21 1e-10 -49.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 583-768
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

KLEGCHLGGGSFGEVYKATHTVHDDVAVKLAKPGKEGQVVMYQKEARKHENSL--ICEHIVPIKGFVECEDDACNC---GLIGIVMKYMENGSLWDFRTT
   |  || | ||||||.| .   .||||  |...   . .  .|||   . |    ..|| . |   | ..  |    . . ||| ||..|.| |.   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCK-LGGHHPNIVRLYGV--CTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KW--LQHPDLLPLINRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLATNL-----------QTSF----GDR-----------CWGTD
.   |...|||     . .  ..||..|||| .|||||   |.||. ...|||.| ||. ..             .     | .           |.  .
HRPKLCMKDLL----SFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NY

S----------------------HKPPEA------------------FRTDLPNS----------------------------------TKIV
.                       .|..                   .| . | .                                   .. 
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase ank2.AA CAMK 588-611 29 8e-06 14.02 In-house 1-37 (425) Show / Hide 
Range on Protein: 588-611
Range on HMM: 1-37/425
Sequence Identity: 29% (11 aa)

HLGGGSFGEVYKATHTVHDD-------------VAVK
 || ||||.|....|.                 ||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIK
Kinase ank2.AA Src 589-628 40 3.1e-05 13.69 In-house 7-45 (255) Show / Hide 
Range on Protein: 589-628
Range on HMM: 7-45/255
Sequence Identity: 40% (16 aa)

LGGGSFGEVYKATHTVHDDVAVKLAKPGKEGQVVMYQKEA
|| | ||||....   . .||||  |||   .. ....||
LGQGQFGEVWMGYWNGNTKVAVKTLKPGT-MSPEAFLQEA
Kinase ank2.AA LISK 588-602 60 0.000121 10.79 In-house 1-15 (296) Show / Hide 
Range on Protein: 588-602
Range on HMM: 1-15/296
Sequence Identity: 60% (9 aa)

HLGGGSFGEVYKATH
 .| |.||.||| ||
EIGKGFFGKVYKGTH
Kinase ank2.AA Pkinase_Tyr 586-616 47 0.000207 15.56 Pfam 4-39 (270) Show / Hide 
Range on Protein: 586-616
Range on HMM: 4-39/270
Sequence Identity: 47% (17 aa)

GCHLGGGSFGEVYKATHT-----VHDDVAVKLAKPG
|  || |.||||||.| .      . .||||  |.|
GKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEG