Gene ANKK4 (Sea Urchin)

ANKK4

Species: Sea Urchin
Alias: Spk395, ANKK4, SPU_008874
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TKL
Family: RIPK

Sequence

Name Sequence Type Origin Length Description Download
ANKK4.AA Protein None 856 None Fasta, JSON
ANKK4.kin_dom Protein Kinase Domain None 204 None Fasta, JSON

Protein domain

Protein domains of ANKK4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Ank ANKK4.AA Ank 110-142 45 1.1e-10 42.85 Pfam 1-33 (33) Show / Hide 
Range on Protein: 110-142
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

DGQTPLHSSSRNGHLDVVKFLIGQGARIDKPTK
||.||||  .|.||..|||.|...|| ..  ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 308-340 39 1.1e-10 42.82 Pfam 1-33 (33) Show / Hide 
Range on Protein: 308-340
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

HGQTSLHYASIKGHLDVVKYLIGQGAQIDKPTK
.|.| ||.|...||..|||.|...|| ..  ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 374-406 45 8.7e-10 39.56 Pfam 1-33 (33) Show / Hide 
Range on Protein: 374-406
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

DGQTPLHSSSRNGHLDVVKYLIGQGAQIDNPIK
||.||||  .|.||..|||.|...|| ..   .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 242-274 45 1.2e-09 39.04 Pfam 1-33 (33) Show / Hide 
Range on Protein: 242-274
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

TGWTPLHAASNNGHVDVVQYLVSQGAQVERGDN
 |.|||| |. .||..||..|...|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 440-472 45 2.7e-09 37.76 Pfam 1-33 (33) Show / Hide 
Range on Protein: 440-472
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

NGFTPLHAASTKGHLDLVAYLVGQGAQVERGDN
.|||||| |. .||.. | .|...|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 176-208 45 6e-09 36.53 Pfam 1-33 (33) Show / Hide 
Range on Protein: 176-208
Range on HMM: 1-33/33
Sequence Identity: 45% (15 aa)

NGFTPLHAASTKGHLDLVAYLVGRGAQVERGDN
.|||||| |. .||.. | .|...|| |   |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 44-76 36 2.4e-08 34.35 Pfam 1-33 (33) Show / Hide 
Range on Protein: 44-76
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

HGQTSLHYASNNGHVDVVKFLIGQRARIDKPSK
.|.| ||.|. .||..|||.|... | ..   .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 275-307 36 1.4e-07 31.63 Pfam 1-33 (33) Show / Hide 
Range on Protein: 275-307
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

NGLTPLQDASHKGHRDIVEYLVGQGAQIDTCDI
.| |||  |...|| ..|..|...|| ..  | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 341-373 33 1.7e-07 31.32 Pfam 1-33 (33) Show / Hide 
Range on Protein: 341-373
Range on HMM: 1-33/33
Sequence Identity: 33% (11 aa)

LGATALHCSSHNGHRDIVEYLVGQGAQIDTCDI
 | |.||. ...|| ..|..|...|| ..  | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 209-241 42 1.8e-07 31.24 Pfam 1-33 (33) Show / Hide 
Range on Protein: 209-241
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

TGWTPLLRASQGGHLDVVQYLLGQAAQVEIGDN
 |.|||  |.. ||..||..||.. | | . |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 473-505 42 2.6e-07 30.65 Pfam 1-33 (33) Show / Hide 
Range on Protein: 473-505
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

TGWTPLLSASQGGHLDVVKYLVGRGAQVKRGTN
 |.|||  |.. ||..|||.|...|| |   ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 506-538 39 2.6e-07 30.63 Pfam 1-33 (33) Show / Hide 
Range on Protein: 506-538
Range on HMM: 1-33/33
Sequence Identity: 39% (13 aa)

NGSTPLQVASRDGQLDVVQYLVGQGAQVERGNN
.| ||| .|.| |...||..|...|| |   ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 407-439 36 3.2e-07 30.3 Pfam 1-33 (33) Show / Hide 
Range on Protein: 407-439
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

LGATALHFASDAGHRDIVEYLVGQGAQVERGTN
 | |.|| |.  || ..|..|...|| |   ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 539-571 42 3.6e-07 30.14 Pfam 1-33 (33) Show / Hide 
Range on Protein: 539-571
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

DGLTALLAASSNGHIDVVKYLVGQGAQVERGAN
|| |.|  |...||..|||.|...|| |    .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 77-109 30 3.3e-05 23.05 Pfam 1-33 (33) Show / Hide 
Range on Protein: 77-109
Range on HMM: 1-33/33
Sequence Identity: 30% (10 aa)

RGATALLFASGVGDRDIVEYLVGQGAQIDTCDI
 | |.|  |.  |. ..|..|...|| ..  | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 143-175 33 9.8e-05 21.33 Pfam 1-33 (33) Show / Hide 
Range on Protein: 143-175
Range on HMM: 1-33/33
Sequence Identity: 33% (11 aa)

SDETALLFASGVGHRDVVEYLVGQGAQVERGTN
  .|.|  |.  || .||..|...|| |   ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank ANKK4.AA Ank 572-609 28 0.001832 16.75 Pfam 1-33 (33) Show / Hide 
Range on Protein: 572-609
Range on HMM: 1-33/33
Sequence Identity: 28% (11 aa)

NGLTPLLAALSNGHLDVAQYLTSKQAKRKEASPEVSDA
.| |||  | ..||..|...| .     . |.. . | 
DGFTPLHLACRCGHTEVVKMLLQ-----HGADVNAQDD
Ank ANKK4.AA Ank 15-43 31 0.006695 14.72 Pfam 5-33 (33) Show / Hide 
Range on Protein: 15-43
Range on HMM: 5-33/33
Sequence Identity: 31% (9 aa)

ALLRAALNGHFDLVRYLVGQGAYIETCDI
.|  |...|| . |..|...|| .   | 
PLHLACRCGHTEVVKMLLQHGADVNAQDD
Kinase ANKK4.AA RIPK 653-856 53 3.5e-137 462.06 In-house 1-229 (290) Show / Hide 
Range on Protein: 653-856
Range on HMM: 1-229/290
Sequence Identity: 53% (123 aa)

LGGGSFGEVYKATHAVHGDVAVKLAKPGKE------DQVKMYKKEARKHENSLICEHIVPIKGFVECEDDACNCGLIGIVMKYMENGSLWDFRTTKW--Q
.|||.||||.||.|...||...|..||.|.      ||..|| ||..||...|.|||||||.||..||...|.|.|.||||.||||||||.|..|||  |
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

QHPDLLPLTNRMVYEMSSGMQFLHSKD--IIHRDLKLENVLVDGDLHVKIADLGLATNLQTS--FGDRC-------------CGTHSHKPPEAFRTDIPN
.|||..||..||..|.|.||..|||..  |||||||.||.|||...||||||.||||....|  ..|||             .||.|..|||.|||| ..
HHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKK

SIMIGTPKYDVYSFAMTLYELLTGIHPYS
.|.. ||||||||||....|.||..|||.
PIKVVTPKYDVYSFAIVMWEVLTQKHPYE
Kinase ANKK4.AA TKL 653-856 24 1.7e-64 220.57 In-house 1-290 (364) Show / Hide 
Range on Protein: 653-856
Range on HMM: 1-290/364
Sequence Identity: 24% (72 aa)

LGGGSFGEVYKATHAVHG---------DVAVKLAKPGKED--------------------------QVKMYKKEARKHENSLICEHIVPIKGFVECEDDA
.| |.||||||...  .|         |||||  |   .|                          . .  ..|  .. ..| ...||...|.. |... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

C-------NCGLIGIVMKYMENGSLWDFRTTKWQQHPDLLPLTNRMVYEMSSGMQFLHSKD--------IIHRDLKLENVLVDGDLH-------------
|       ..| ..||| |...|||... .         .... |.......||..|||..        ||||||| .|.||| ...             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-VKIADLGLATNLQTSFGDRC---------------------CGTHSHKPPEAFRTDIPNSI----------MIGTPKYDVYSFAMTLYELLTGIHPYS
 .||.|.||......|... .                     |||  . .||..| .....              ..| |||||.. |.|.||. .||.
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY
Kinase ANKK4.AA Pkinase 653-856 30 6.9e-30 106.76 Pfam 7-213 (293) Show / Hide 
Range on Protein: 653-856
Range on HMM: 7-213/293
Sequence Identity: 30% (69 aa)

LGGGSFGEVYKATHAVHGD-VAVKLAKPGKEDQVKMYKK----EARKHENSLICEHIVPIKGFVECEDDACNCGLIGIVMKYMENG----SLWDFRTTKW
.| ||||.|||..|   |. ||||  |  .|.  | . .    |.. . .   ...|| .....| .|. .      .|| |.|.|    .|.|. .|  
IGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIY------MVMEYCEGGLYVMDLFDYIST--

QQHPDL---LPLTNRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHV----KIADLGLA----TNLQTSFGDRCCGTHSHKPPEAFRTDIPNSIMIG
..|  .        ...|.. .|....||. |||||||.||.|.| . |.    ||.| |||    .  .. . .. |||    .||           | 
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTF-CGTPWYMAPEV----------IR

-----TPKYDVYSFAMTLYELLTGIHPYS
     .|| |..|.  .|||.|.|  |..
GGQYYGPKVDMWSCGCILYEMLCGRPPFP
Kinase ANKK4.AA MLK 647-856 26 1.1e-26 89.64 In-house 1-237 (291) Show / Hide 
Range on Protein: 647-856
Range on HMM: 1-237/291
Sequence Identity: 26% (67 aa)

KLEGCHLGGGSFGEVYKATHAVHGD-----VAVKLAKPGKEDQVKMY------KKEAR-----KHENSLICEHIVPIKGFVECE-DDACNCGLIGIVMKY
 ..  ..| ||||.|.|..     |     |||| ..  ..| ...|      ..|.|     .|.|  .|  |....|   ..  . |      ||| |
IQFHEWIGSGSFGKVWKGRWRNK-DIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPC--IIQFYGVCLQPPCHFC------IVMEY

MENGSLWDFR---TTKWQQ--HPDL------LPLTNRMVYEMSSGMQFLHSKD---IIHRDLKLENVLVD------GDLHVKIADLGLATNLQTSFGD--
.|.||| ..    ..||    |..       . . ..  . ...||..|||..   |||||||  |.|.|      .....||.| |... ....  .  
CEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNM

-RCCGTHSHKPPEAF--RTDIPNSIMIGTPKYDVYSFAMTLYELLTGIHPYS
   .||     ||..      ..|.     | ||.|... |.|.||. .||.
MSNAGTYAWMAPEVIQQFRCEKYSE-----KCDVWSWGVVLWEMLTREVPYK
Kinase ANKK4.AA STE 648-856 21 1.6e-25 87.2 In-house 1-269 (359) Show / Hide 
Range on Protein: 648-856
Range on HMM: 1-269/359
Sequence Identity: 21% (60 aa)

LEG-CHLGGGSFGEVYKATHAVHGD----------------VAVKLAKPGKE-----------------DQVKMYKKEARKHENSLI-CEHIVPIKGFVE
.||   .| |.||.|||| .   ..                .|.|  .  ..                 .... ..|| . . ..   ...||   |  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

CEDD-ACNCGLIGIVMKYMENGSLWDFRTTKWQQHPDL-----------LPLTNRMVYEMSSG-MQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLAT
 |..   |.. . |.| ||..||| |.  .|.    .|            ..  .....   | ...|||. |||||.|  |.|.     ||..| |...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

NLQTS------------------FGDRCCGTHSHKPPEAFRTDIPN-SIMIGTPKYDVYSFAMTLYELLTGIHPYS
.|. |                    . ..||  .  ||  . .  . .   .| | |..|.  |. |..|| .|..
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDT-KCDIWSLGCTIIEMATGKPPWH
Kinase ANKK4.AA Ciliate-E2-Unclassified 653-856 21 1.5e-24 82.13 In-house 7-271 (352) Show / Hide 
Range on Protein: 653-856
Range on HMM: 7-271/352
Sequence Identity: 21% (58 aa)

LGGGSFGEVYKATHAVHGDV-AVKLAKPGKEDQVKMYKK-----------EARKHENSLI------------CEHIVPIKGFVECEDDACNCGLIGIVMK
.| |.||.|||. |  .. . | | .|  ... .| ...           . .|. ..              . |.. .| | . .|. .    | ||| 
IGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN----IYIVME

YMENGSLWDFRTTKWQ--------------QHPDLLPLTN-----RMVYEMSSGMQFLHSKD-IIHRDLKLENVLVDGDL---HVKIADLGLAT------
|.|.|.||.. . ...              ..      .      .. ..  .| ..||.|  |||||.|.||.|.| .    ..||.|.|..       
YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNN

-----------NLQTSFGDRCCGTHSHK----PPEAFRTDIPNSIMIGTPKYDVYSFAMTLYELLTGIHPYS
           ...    . .||| . .    .|| ..   ..       | |..|. . |||.|.| .|..
NCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA--YKCDIWSLGVILYEMLFGYYPFY
Kinase ANKK4.AA Ciliate-E2 653-855 19 2e-23 77.29 In-house 7-296 (365) Show / Hide 
Range on Protein: 653-855
Range on HMM: 7-296/365
Sequence Identity: 19% (60 aa)

LGGGSFGEVYKATH-AVHGDVA-----VKLAKPG--------KEDQVKMYKK---EARKHENSLI--------------------CEHIVPIKGFVECED
.| |.|| |||...  |  ..|      |. ...        |.  .|..||   |. | |....                    . .|. .. . . .|
IGQGNFGSVYKCKVWKVQKQFAIKIIDQKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKD

DACNCGLIGIVMKYMENGSLWDFRTTKWQQHPDLLP--------LTNRMVYEMSS---------------GMQFLHSKD-IIHRDLKLENVLVDGDLHVK
| .    | .|| | . |.|.|.   ......  ..           .. ..  .               ....||||  |||||.|.||.|.     .|
DNN----IYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IK

IADLGLAT---------------NLQTSFG-------------------DRCCGTHSHKPPEAFR-TDIPNSIMIGT---PKYDVYSFAMTLYELLTGIH
|.|.||..               .. .  .                   ...|||   ..|| ..  .. |    ..    | |..|. ..|||.|.| .
IIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ-QKQKGYDYKCDIWSLGVILYEMLFGKP

PY
|.
PF
Kinase ANKK4.AA Dicty4-Unclassified 763-855 40 2e-22 73.55 In-house 121-208 (263) Show / Hide 
Range on Protein: 763-855
Range on HMM: 121-208/263
Sequence Identity: 40% (38 aa)

GMQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLATNLQTSFGDRCCG-THSHKPPEAFRTDIPNSIMIGTPKYDVYSFAMTLYELLTGIHPY
|||.||....||||.|  |.|.| .  .||||.|..      |     . |     ||  .    |.      | ||||.|| ||||.||  ||
GMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQ------KSDVYSYAMMLYELATGDEPY
Kinase ANKK4.AA TK 653-850 17 3.4e-22 70.53 In-house 7-389 (486) Show / Hide 
Range on Protein: 653-850
Range on HMM: 7-389/486
Sequence Identity: 17% (67 aa)

LGGGSFG---EVYKATHAVHG--------------------------DVAVKLAKPGKEDQVKMYKK-----------------EARKHENSLI-CEHIV
|| | ||   ||||..   ..                          .||||  |.| ... .. .                  |. .  .||  ...||
LGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIV

PIKG-FVECEDDACNC-----GLIGIVMKYMENGS--------LWDFRTT------------------------------------------------KW
 . |  .. |   |       . . ||| ||..|.        |.. | .                                                 .
RLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIK

QQHPDLLP-----------------LTNRMVYEMS----SGMQFLHSKDI------IHRDLKLENVLVDGDLH-----------VKIADLGLATN----L
.. |.|                   || .    |.    .||..|||| .      .||||   |.||. ...           .|||| ||. .    |
DHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVL

QTSFGD--RCCGTHSHK------------------------------PPEAFRTDIPNSI---MIGTPKYDVYSFAMTLYELLT
    ..    . ..|..                              .||.... .. .     . |.| ||.||  ...|..|
ARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase ANKK4.AA TKL-Unique 650-856 27 6.5e-21 70.62 In-house 2-235 (290) Show / Hide 
Range on Protein: 650-856
Range on HMM: 2-235/290
Sequence Identity: 27% (66 aa)

GCHLGGGSFGEVYKATHAVHGDVAVKLAKPGKEDQVKMYKKEARKHENSLICEH----IVPIKGFVECEDDACNCGLIGIVMKYMENGSLWDFRTTKWQQ
.  .|.|..|.|||....   .||.|  .| .||. .  ..| ... | . . |    || . |.  | |.    .   ||| |.. ||| |  ..    
WNKIGEGGYGQVYKGKWRGY-PVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGY--CMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNN

H---PDLLPLTNRMVYEM----SSGMQFLHSKD--IIHRDLKLENVLVDGD-----LHVKIADLGLATNLQTS----FG-------DRCCGTHSHKPPEA
    .. ..|.. ... |    ..|| .||...  |||||||  |.||| .     . .||.| ||.... ..    ..       .  ||.    .|| 
NNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

FRTDIPNSIMIGTPKYDVYSFAMTLYELLTGIH------PYS
.|       .. . | |||||.. |.|..|.        ||.
LRMNF---CQY-SEKSDVYSFGIVLWEIATRKITKTYKKPYQ
Kinase ANKK4.AA Dicty4 763-812 40 3.7e-16 50.56 In-house 124-180 (277) Show / Hide 
Range on Protein: 763-812
Range on HMM: 124-180/277
Sequence Identity: 40% (23 aa)

GMQFLHSKD--IIHRDLKLENVLVDGDLHVKIADLGLAT----NLQTSF-GDRCCGT
||. ||. .  |||||||  | ||| .. ||..|.||..      . ..  .  |||
GMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGT
Kinase ANKK4.AA S_TKc 647-856 22 7.8e-16 55.31 SMART 1-231 (231) Show / Hide 
Range on Protein: 647-856
Range on HMM: 1-231/231
Sequence Identity: 22% (59 aa)

KLEGCHLGGGSFGEVYKATHAV-HGDVAVKLAKPGKEDQVKMYKKEARKHENSLICEHIVPIKGFVECEDDACNCGLIGIVMKYMEN--GSLWDFRTTKW
   . ..| |.||.|||..|   .  ||.|  |       .. ..| . ...   ...|| .... .        . . .|| |...  |.| |.   . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRG

QQ---HPDLLPLTNRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLATNLQTSFGDRCCGTHSHKPPEAFRTDIPNSIMIGTPKYDVYS
 .   .|     . ...|.. ......||. ||||||| ||.|.|   |.||.| |||. |     . .|||    .|| .          |..| |..|
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL--------GYGKCKCDWWS

FAMTLYELLT----------------------------------------GI-------HPYS
.  .|||.|.                                                 ||. 
CGCILYEMLCGYPPFPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase ANKK4.AA Pkinase_Tyr 701-798 35 1.4e-13 46.67 Pfam 63-158 (270) Show / Hide 
Range on Protein: 701-798
Range on HMM: 63-158/270
Sequence Identity: 35% (35 aa)

CEHIVPIKGFVECEDDACNCGLIGIVMKYMENGSLWDFRTTK--WQQHPDLLPLTNRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLA
...||   | . ....      | ||| ||..|.| |.  ..  ..|....  | . | .. ..||..|.|| .|||||   |.||. ...|||.| |||
HPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQ-MCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase ANKK4.AA TyrKc 647-849 20 1.8e-11 -37.21 SMART 1-280 (280) Show / Hide 
Range on Protein: 647-849
Range on HMM: 1-280/280
Sequence Identity: 20% (58 aa)

KLEGCHLGGGSFGEVYKATHAVHGDVAVKLAKPGKEDQVKMYKKEARKHENSL--ICEHIVPIKGFVECEDDACNC---GLIGIVMKYMENGSLWDFRTT
   |  || | ||||||.|     .||||  |...   ...  .|||   . |    ..|| . |   | ..  |    . . ||| ||..|.| |.   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCK-LGGHHPNIVRLYGV--CTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KWQQHPDLLPLTNRMVYEMSSGMQFLHSKDIIHRDLKLENVLVDGDLHVKIADLGLATNLQTS-------FGDRC----CGT------------------
.  .    ..    . .  ..||..|||| .|||||   |.||. ...|||.| ||. ..             |     .|                   
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

-----------------------HSH-----KPPEAFRTDIPNSIMIGTPKY-----------DVYSFAM--------------TLYELL
                       ..      ....  . .. .  .   |..           ..|.                 ...|..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase ANKK4.AA Dicty4 837-856 55 2e-06 17.95 In-house 199-218 (277) Show / Hide 
Range on Protein: 837-856
Range on HMM: 199-218/277
Sequence Identity: 55% (11 aa)

DVYSFAMTLYELLTGIHPYS
|||||.. |.|.||.  ||.
DVYSFGIVLWEILTRQEPYQ
Kinase ANKK4.AA Pkinase_Tyr 650-684 42 0.000662 13.85 Pfam 4-43 (270) Show / Hide 
Range on Protein: 650-684
Range on HMM: 4-43/270
Sequence Identity: 42% (17 aa)

GCHLGGGSFGEVYKATHA-----VHGDVAVKLAKPGKEDQ
|  || |.||||||.|        . .||||  |.|  ..
GKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHE
Kinase ANKK4.AA Dicty4 653-665 76 0.006586 5.73 In-house 7-19 (277) Show / Hide 
Range on Protein: 653-665
Range on HMM: 7-19/277
Sequence Identity: 76% (10 aa)

LGGGSFGEVYKAT
.|.||||||||.|
IGKGSFGEVYKGT
Kinase ANKK4.AA Pkinase_Tyr 837-850 42 3.431647 1.27 Pfam 196-209 (270) Show / Hide 
Range on Protein: 837-850
Range on HMM: 196-209/270
Sequence Identity: 42% (6 aa)

DVYSFAMTLYELLT
||.||  ...|..|
DVWSFGVLMWEIFT