TKL3

Species: Sea Urchin
Alias: SpTKL1b, SPU_008602, TKL3, Spk318
External Links: Sea Urchin Project Link
Annotation:

Classification

Group: TKL
Family: TKL-Sp1

Sequence

Name Sequence Type Origin Length Description Download
TKL3.AA Protein None 421 None Fasta, JSON
TKL3.kin_dom Protein Kinase Domain None 261 None Fasta, JSON

Protein domain

Protein domains of TKL3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TKL3.AA TKL-Sp1 157-417 86 3.9e-245 775.39 In-house 1-263 (263) Show / Hide
Range on Protein: 157-417
Range on HMM: 1-263/263
Sequence Identity: 86% (227 aa)

LDMGPVVGKGQFGVVHRASWRGTPVAVKKISMMGSRKDEIEKEVAIHRRACHPNIVQMMALGYQGNEAFLVMQFIEGPSLHTVIFPDRDDVKIPLDWAKQ
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||||||.
LDMGPVVGKGQFGVVHRASWRGTPVAVKKISMMGSRKDEIEKEVAIHRRACHPNIVQMMALGYQGKEAFLVMQFIEGPSLHTVIFPDRDDVKIPLDWAKK

LQISCEVLQAVTFMHACYILHLDIKPANILVDSATIRPYICDLGLAHIKNRNLMSQSA--VNMRGTPCFMPPEALGATEPGYRHSNKHDIWSVAGTLVEL
.||||||||||||||||.||||||||||..|..||.||||||||||||||||.||||.  ||||||||.||||.....|||.||.|||||||||.|.|||
MQISCEVLQAVTFMHACNILHLDIKPANVMVERATRRPYICDLGLAHIKNRNHMSQSTSMVNMRGTPCHMPPEMVQKQEPGWRHPNKHDIWSVACTFVEL

YSMKRLWGDSMNPLVLMARIYTGQMGKPDSLTAVDPKVQKILEPCFEQKPEKRPSASNLLDQF
|||||||||||....||.||.||||.||..||.|||||||||||||.|||||||||..|||||
YSMKRLWGDSMEFMALMRRILTGQMSKPEILTKVDPKVQKILEPCFDQKPEKRPSAEDLLDQF

Kinase TKL3.AA TKL 163-417 19 2.9e-64 219.81 In-house 1-364 (364) Show / Hide
Range on Protein: 163-417
Range on HMM: 1-364/364
Sequence Identity: 19% (74 aa)

VGKGQFGVVHRASWRG----------TPVAVKKISMMGSRK----------------------------DEIEKEVAIHRRACHPNIVQMMALGYQGNE-
.|.| ||.|... |||          ..|||||.... . .                            ...|.|. ...| .||||||.|.   ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------AFLVMQFIEGPS-LHTVIFPDRDDVKIPLDWAKQLQISCEVLQAVTFMHACY--------ILHLDIKPANILVDS-------------
             ..||....| | ||...            | . .... .. ... ..|..         |.| |.|..|||||.             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN

ATIRPYICDLGLAHIKNR---NLMSQSAVN--------------MRGTPCFMPPEALGATEP------------GYRHSNKHDIWSVAGTLVELYSMKRL
|.... |||.||.  ...   . .......               .|||..|.||.|  ...            |.  | |.|..| .  | |... .| 
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRP

WGDSMNPLVL---------MARIYTGQMGKPD----------SLTAVDPKVQKILEPCFEQKPEKRPSASNLLDQF
. | ... ..         | ... |.   ..            . ..| . |... | ...||||||.. .|...
YYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase TKL3.AA S_TKc 157-421 23 2.3e-44 154.61 SMART 1-231 (231) Show / Hide
Range on Protein: 157-421
Range on HMM: 1-231/231
Sequence Identity: 23% (65 aa)

LDMGPVVGKGQFGVVHRASWRG--TPVAVKKISMMGSRKDEIEKEVAIHRRACHPNIVQMMALGYQGNEAFLVMQFIEG--PSLHTVIFPDRD---DVKI
 ... ..||| ||.|... ...    ||.|.|.      . |..|..|...  |||||..    .  .. ..|| ...|   .|...|   .    ....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

PLDWAKQLQISCEVLQAVTFMHACYILHLDIKPANILVDSATIRPYICDLGLAHIKNRNLMSQSAVNMRGTPCFMPPEALGATEPGYRHSN-KHDIWSVA
|  .|.   . .....|. ..|   |.| |.||.|||.|.   .  ||| ||| .            . ||| .|.|| |        ..  | |.||. 
PE-HAR--FYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL---------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCG

GTLVELYSMKRLWGDSMNPLVLMARIYTGQMGKPDSLTAVDPKVQKILEPCFEQKPEKRPSASNLLDQF-----NDLI
 .| |... . ..    .. ... .|              .| .  ... |..  |||||.|  .|           .
CILYEMLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase TKL3.AA Pkinase 157-417 22 5.2e-39 139.02 Pfam 1-293 (293) Show / Hide
Range on Protein: 157-417
Range on HMM: 1-293/293
Sequence Identity: 22% (67 aa)

LDMGPVVGKGQFGVVHRASWRGTP--VAVKKISMMGSRKDEIEK-----EVAIHRRACHPNIVQMMALGYQGNEAFLVMQFIEGP----SLHTVIFPDRD
.  | ..|.| ||.| .. ..||.  ||||.|.  . .... .      |..|..| .|||||..    . ...  .|| . ||     .|...|     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

DVKIPL--DWAKQLQISCEVLQAVTFMHACYILHLDIKPANILVDSATIRP----YICDLGLAHIKNRNLMSQSAVNMRGTPCFMPPEALGATEPGYRHS
. . ..  ..     .  ..|... ..|.. |.| |.||.|||.|  .  .     ||| |||  .. .  .. .    ||| .|.|| .     |  ..
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIR---GGQYYG

NKHDIWSVAGTLVELYSMKRLWGDS-----MNPLVLMARIYTGQMGKPDSLT------------------AVDPKVQKILEPCFEQKPEKRPSASNLLDQ
 | |.||.  .| |... . .. ..     ........||  ..   . . .                  ....  ..... |....|.|||.|  .|  
PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH

--F
  |
PWF

Kinase TKL3.AA STE 157-418 20 5e-31 106.84 In-house 1-359 (359) Show / Hide
Range on Protein: 157-418
Range on HMM: 1-359/359
Sequence Identity: 20% (76 aa)

LDMGPVVGKGQFGVVHRASWR-----------------GTPVAVKKISMMGSR------------------KDEIEKEVAIHRRAC--HPNIVQMMALGY
..   ..||| ||.|..|  .                 |. .|.|....  ..                  ...|.||. |...    |||||.     .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

QG-------NEAFLVMQFIEGPSLHTVIF-----PDRDD------VKIPLDWAKQLQISCEVLQA-VTFMHACYILHLDIKPANILVDSATIRPYICDLG
..       .| ...| ...| ||  .|      .....       ..| .. .   | ...|..   . |   | | ||||||||.        .|| |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIA--YICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFG

LAHIKNRN--------------LMSQSAVNMRGTPCFMPPEALGATEPGYR---HSNKHDIWSVAGTLVELYSMKRLW--GDSMNPLVLMARIYTGQM--
.. . . .               |.|    . ||| .| || .   . | |   .. | ||||.  |..|.   |  |  .  |  . .... |  |.  
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQF

--------GKPDSLTAVD-------------------PKVQKILEPCFEQKPEKRPSASNLLD---QFN
        . |   . ..                   |. .  .. |..  |.|||.|| ||     | 
EQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase TKL3.AA TKL-Unique 159-346 24 6.9e-26 88.38 In-house 1-213 (290) Show / Hide
Range on Protein: 159-346
Range on HMM: 1-213/290
Sequence Identity: 24% (54 aa)

MGPVVGKGQFGVVHRASWRGTPVAVKKISM-MGSRKDEIE---KEVAIHRRAC-HPNIVQMMALGY----QGNEAFLVMQFIEGPSLHTVIF-----PDR
 . ..| | .|.| .. |||.|||.|...   .|......   .|| .  .   |||||. |.       . .. ..|| ...| ||. |.         
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

DDVKIPLDWAKQLQISCEVLQAVTFMHACY--ILHLDIKPANILVDSA-TIRPY---ICDLGLAHIKNRNLMSQSAVNMR---------GTPCFMPPEAL
   ...|........   . |.  . | |   |.|.|.|. |.|||.. .| ..   ||| ||. ....  .... .|.          |..  |.|| |
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSK--INKMTNNEHKGTRNQTRCGSFRWMAPEVL

GATEPGYRHSNKHDIWS
   .  .  |.| |..|
RMNF--CQYSEKSDVYS

Kinase TKL3.AA MLK 157-329 24 1.4e-25 85.74 In-house 1-205 (291) Show / Hide
Range on Protein: 157-329
Range on HMM: 1-205/291
Sequence Identity: 24% (51 aa)

LDMGPVVGKGQFGVVHRASWRGTP-----VAVKKIS-------MMGSRKDEIEKEVAIHRRACHPN----IVQMMALGYQ-GNEAFLVMQFIEGPSLHTV
..   ..|.| ||.|... ||..      ||||..         ... ....|.|. . |. .|||    |.| ..   | ... ..||...|| ||..|
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

I-----------FPDRDDVKIPLDWAKQLQISCEVLQAVTFMHACY---ILHLDIKPANILVDS-----ATIRPYICDLGLAH-IKNR--NLMSQSAVNM
.            ... |. ...| |  ....  . ... . |.     | | |.|. |||.|      .     ||| |... ....  | ||     .
LHGARSKWMDANHNQKNDRVYDHDHA--MNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMS-----N

RGTPCFMPPEAL
.||. .| ||..
AGTYAWMAPEVI

Kinase TKL3.AA TAK1 157-416 24 1.5e-24 79.76 In-house 1-284 (284) Show / Hide
Range on Protein: 157-416
Range on HMM: 1-284/284
Sequence Identity: 24% (73 aa)

LDMGPVVGKGQFGVVHRASWRGTPVAVKKISMM-----GSRKDEIEKEVAIHRRACHPNIVQMMAL-GYQGNEAFLVMQFIEGPSLHTVIFPDRDDVKIP
 .   .|||| .||| .|.||.. .|||..  .     .. . .||.|.    |. ||||..   .    .. . ||| .... ||| ...  ..     
IQNEHFVGKGTYGVVCKAKWRNKEIAVKRFEFIKYSSEECEQKNIEREIMQWSRVDHPNIIKLYGMYACHRQCQCLVMEYMDCGSLHNFLHGAKPKWEYT

LDWAKQ--LQISCEVLQAVTFMHACY---ILHLDIKPANILVDSATIRPYICDLGLAHIKNRNLMSQSAVNMRGTPCFMPPEA-----------------
.. |    .|..    |.| ..|.     . | ||||.| |  .      ||| |..       |.|.  ..|||. .| ||.                 
HAHAMSWMHQCA----QGVAYLHSMQPKPQIHRDIKPQNMLLCNKHRTLKICDFGTFCD-----MHQMMTCNRGTCRWMAPEVRELFDFKSNRIIINQPT

-LGATEPGYRHSNKHDIWSVAGTLVELYSMKRLWGDSMNP---LVLMARIYTGQMGKPDSLTA---VDPKVQKILEPCFEQKPEKRPSASNLLDQ
       .   . | || | . .. |. | |    . |||     .|  |..|.  .|  .|    . .   .  . | .. |||||| .     
GFQKVFRCEKYNMKCDIYSWGIIMWEVISRKHPYDHIMNPNSAYRIMWAIHNGN--RPPMETNRSDCPKRIEQFMKCCWDDNPEKRPSMQECVKY

Kinase TKL3.AA MOS 157-291 29 1.5e-24 78.18 In-house 1-151 (299) Show / Hide
Range on Protein: 157-291
Range on HMM: 1-151/299
Sequence Identity: 29% (47 aa)

LDMGPVVGKGQFGVVHRASWRGTPVAVKKIS-----MMGSRKDEIEKEVAIHRRACHPNIVQMMALG---YQGNE--AFLVMQFIEGPSLHTVIF-----
  .  . |.| || |  | ..|.||||| .         .|.     || . .|. |.|||. ||..     . .  .. .| .  . .|| ||      
VCLCQMIGRGGFGSVWKAQYCGRPVAVKQVNKCTKNLKAMRR-SFWAEVNY-LRLRHDNIVRVMAVSQRSPEDFNNLGTIIMECGGNQTLHQVIYEPTRH

PD--------RDDVKIPLDWAKQLQISCEVLQAVTFMHACYILHLDIKPANILVDSAT
|         |      |  .. . .|  |. |... |.. |||||.|||||.||  |
PPGDAGIIHCR-----MLILMHCCKYSLDVVNALQYCHHQNILHLDVKPANIIVDEGT

Kinase TKL3.AA TK 157-417 13 4.7e-21 66.63 In-house 1-486 (486) Show / Hide
Range on Protein: 157-417
Range on HMM: 1-486/486
Sequence Identity: 13% (67 aa)

LDMGPVVGKGQFG---VVHRASWRG---------------------------TPVAVKKIS--MMGSRKDEIE----------------KEVAIHR--RA
. .| . |.||||   .|... |||                           |||||| .      | .....                 | .. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

CHPNIVQMMALGYQG------------NEAFLVMQFIEGPS----LHTVIFPDRDDVKI-----------------------------------------
 |||||.. .   ||                .|| . .. .    |..     |.. .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------PLDWAKQLQISCEVLQAVTFMHAC------YILHLDIKPANILVDSATIR----------PYICDLGLAH
                              .|. . .| ... . ..  ..|..       . | |.   |.||..  ..            |.| ||. 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

IKN----RNLM---SQSAVNMRGTPC-------------------------FMPPEALGATEPGYR-----HSNKHDIWSVAGTLVELYS-MKRLWGDSM
 .     | .       ... .||..                          |.||.|   ..        .. | |.||   .. |...  .  ..  |
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

NP---------LVLMARIYTGQ-------------MGKPDSLTAVD-------------PKVQKILEPCFEQKPEKRPSASNLLDQF
.            .| .. .|.             | .|    . |             . .. ..  |.. .||.||. | |..|.
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase TKL3.AA LISK-DD1 162-327 28 6.8e-20 68.76 In-house 1-201 (290) Show / Hide
Range on Protein: 162-327
Range on HMM: 1-201/290
Sequence Identity: 28% (58 aa)

VVGKGQFGVVHRASWRGTPVAVKKISM--MGSRKDEIEK----EVAIHRR---ACHPNIVQMMALGYQ-------------GNEAFLVMQFIEGPSLHTV
  ||| || | .... |||||.|||.     . ... .|    |... .      ||||||    ..              . . ..|  ||||  ||  
EIGKGSFGKVYKGCYFGTPVAIKKIHKQPNDPNDPDYWKFMQREIKMLKNLLNIRHPNIVQFIGICEHPLASPSLVNRLLNESSLYIVTEFIEGGDLHWY

IFP-DRDDV-------KIPLDWAKQLQISCEVLQAVTFMHACYILHLDIKPANILVDSA---TIRPYICDLGLAHIKNRNLMSQSA--VNMRGTPCFMPP
..    ||        |||. | . . |.  . .|  . |.  |.| | |  |||||      .|  .||.|.| . .    .|      . ||. .|.|
LKNTPFDDTPEQYIHHKIPIPWKLRVKIALDIACAMAYLHSKNIIHRDLKSKNILVDENGDSQWRIKVCDFGFARMFEQKKNQQNNRHMTICGTDNWMAP

E
|
E

Kinase TKL3.AA CAMK 162-214 15 2.1e-14 42.13 In-house 1-103 (425) Show / Hide
Range on Protein: 162-214
Range on HMM: 1-103/425
Sequence Identity: 15% (16 aa)

VVGKGQFGVVHRASWRGTP--------------VAVKKISM-----------------------------MGSRKDEIEKEVAIHRRAC-------HPNI
. |.|.||.|...  . |.              ||.| |.                               .. ......|..|...         ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQM
...
IKL

Kinase TKL3.AA TyrKc 157-417 19 2.3e-14 9.63 SMART 1-280 (280) Show / Hide
Range on Protein: 157-417
Range on HMM: 1-280/280
Sequence Identity: 19% (56 aa)

LDMGPVVGKGQFGVVHRASWRGTPVAVKKISMMGSRKDEIEKEVAIHRRA--CHPNIVQMMALGYQG-------NEAFLVMQFIEGPSLHTVIFPDRDDV
. .| . | |.||.|... |. ..||||..      . .. .|  | ..    |||||.. .   |.          ..|| . .. .|.  .   |.. 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-

KIPLDWAKQLQISCEVLQAVTFMHACYILHLDIKPANILVDSATIRPYICDLGLAHIKNRN--------LMSQSA-VNMRG-TPCF-MPPEALGATEPGY
   | ... |...  . .   . |   . | |.   |.||..   .  |.| ||.                ...   . ..  |   |.||..      .
---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----NYG

RHSNKHDIWSVAGTLVELYSM-KRLWGDS----MNPLVLMARIYTG-QMGKPDS-LTA-----VDPKVQKILEPCFEQKPEKRPSASNLLDQF
. . | |.||   .. |...  .  . .     |..  ..... .|  | .|.. .         ... .| . | . .||.||. |.. ..|
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase TKL3.AA CAMK 263-327 23 3.1e-13 38.28 In-house 188-290 (425) Show / Hide
Range on Protein: 263-327
Range on HMM: 188-290/425
Sequence Identity: 23% (24 aa)

VLQAVTFMHACYILHLDIKPANILVDSAT----------------IRPYICDLGLA--HIKNRNLM-------------------SQSAVNMRGTPCFMP
...|| ..| . | |.|.|| |||.|.                      |.| |.|   ... |..                    |    . |||..|.
ICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMA

-PE
 ||
APE

Kinase TKL3.AA Pkinase_Tyr 157-238 26 4.1e-13 45.04 Pfam 1-96 (270) Show / Hide
Range on Protein: 157-238
Range on HMM: 1-96/270
Sequence Identity: 26% (25 aa)

LDMGPVVGKGQFGVVHRASWR------GTPVAVKKI--SMMGSR--KDEIEKEVAIHRRA-CHPNIVQMMALGY-QGNE--AFLVMQFIEGPSLHT
. .| . |.|.||.|... |.      ..|||||..  . | .   ...  .|..| .    |||||....  . ||     ..|| . .. .|..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

Kinase TKL3.AA MLK 394-417 33 0.00192 7.96 In-house 268-291 (291) Show / Hide
Range on Protein: 394-417
Range on HMM: 268-291/291
Sequence Identity: 33% (8 aa)

KILEPCFEQKPEKRPSASNLLDQF
| .. | .|.|.|||| .  . ..
KLMKQCWNQDPHKRPSFRQIVQHL

Kinase TKL3.AA MOS 393-419 29 0.061347 1.97 In-house 273-299 (299) Show / Hide
Range on Protein: 393-419
Range on HMM: 273-299/299
Sequence Identity: 29% (8 aa)

QKILEPCFEQKPEKRPSASNLLDQFND
...   | ...|| ||||  |.     
RQLIQKCWPKQPEQRPSARQLKHELEM

Kinase TKL3.AA TKL-Unique 393-417 20 0.06478 2.76 In-house 266-290 (290) Show / Hide
Range on Protein: 393-417
Range on HMM: 266-290/290
Sequence Identity: 20% (5 aa)

QKILEPCFEQKPEKRPSASNLLDQF
..... |. . |..||| .. .   
RDLIQQCWHHDPSQRPSFDEIIHRL

Kinase TKL3.AA Pkinase_Tyr 399-417 36 0.271777 5.0 Pfam 252-270 (270) Show / Hide
Range on Protein: 399-417
Range on HMM: 252-270/270
Sequence Identity: 36% (7 aa)

CFEQKPEKRPSASNLLDQF
| ...||.||. | .. |.
CWHYDPEDRPTFSEIHEQL