Gene TKL2 (Sea Urchin)

TKL2

Species: Sea Urchin
Alias: Spk394, TKL2
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Sp1

Sequence

Name Sequence Type Origin Length Description Download
TKL2.kin_dom Protein Kinase Domain None 261 None Fasta, JSON
TKL2.AA Protein None 423 None Fasta, JSON

Protein domain

Protein domains of TKL2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TKL2.AA TKL-Sp1 159-419 87 2.6e-244 772.77 In-house 1-263 (263) Show / Hide 
Range on Protein: 159-419
Range on HMM: 1-263/263
Sequence Identity: 87% (230 aa)

LDMGPVVGKGQFGVVHRASWRGTPVAVKKISMMGSRKDEIEKEVAIHRRACHPNIVQMMALGYQGREAFLVMQFIEGPSLHTVIFPDRDDVKIPLDWAKK
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||
LDMGPVVGKGQFGVVHRASWRGTPVAVKKISMMGSRKDEIEKEVAIHRRACHPNIVQMMALGYQGKEAFLVMQFIEGPSLHTVIFPDRDDVKIPLDWAKK

LQISCEVLQAVTFMHACNILHLDIKPANILVESATIRPYICDLGLAHIKNRNLMSQSA--VNIRGTPCFMPPEALGATEPGYRHSNKHDIWSVAGTLVEL
.|||||||||||||||||||||||||||..||.||.||||||||||||||||.||||.  ||.|||||.||||.....|||.||.|||||||||.|.|||
MQISCEVLQAVTFMHACNILHLDIKPANVMVERATRRPYICDLGLAHIKNRNHMSQSTSMVNMRGTPCHMPPEMVQKQEPGWRHPNKHDIWSVACTFVEL

YSNKRLWGDSVHPLALMARILTGQMSKPESLTAVDSKVQKILEPCFRQKPEKRPAASDLLDQF
||.|||||||....|||.|||||||||||.||.||.||||||||||.|||||||.|.||||||
YSMKRLWGDSMEFMALMRRILTGQMSKPEILTKVDPKVQKILEPCFDQKPEKRPSAEDLLDQF
Kinase TKL2.AA TKL 165-419 19 6.5e-62 212.0 In-house 1-364 (364) Show / Hide 
Range on Protein: 165-419
Range on HMM: 1-364/364
Sequence Identity: 19% (72 aa)

VGKGQFGVVHRASWRG----------TPVAVKKISMMGSRK----------------------------DEIEKEVAIHRRACHPNIVQMMALGYQGRE-
.|.| ||.|... |||          ..|||||.... . .                            ...|.|. ...| .||||||.|.   ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------AFLVMQFIEGPS-LHTVIFPDRDDVKIPLDWAKKLQISCEVLQAVTFMHACN--------ILHLDIKPANILVES-------------
             ..||....| | ||...            | ...... .. ... ..|..|        |.| |.|..|||| .             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN

ATIRPYICDLGLAHIKNR---NLMSQSAVN--------------IRGTPCFMPPEALGATEP------------GYRHSNKHDIWSVAGTLVELYSNKRL
|.... |||.||.  ...   . .......              ..|||..|.||.|  ...            |.  | |.|..| .  | |... .| 
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRP

WGDSVHPLAL---------MARILTGQMSKPE----------SLTAVDSKVQKILEPCFRQKPEKRPAASDLLDQF
. |  ..  .         | ... |.   .             . ..  . |... |  ..||||| ....|...
YYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase TKL2.AA S_TKc 159-419 23 7.5e-43 149.6 SMART 1-231 (231) Show / Hide 
Range on Protein: 159-419
Range on HMM: 1-231/231
Sequence Identity: 23% (64 aa)

LDMGPVVGKGQFGVVHRASWRG--TPVAVKKISMMGSRKDEIEKEVAIHRRACHPNIVQMMALGYQGREAFLVMQFIEG--PSLHTVIFPDRD---DVKI
 ... ..||| ||.|... ...    ||.|.|.      . |..|..|...  |||||..    .   . ..|| ...|   .|...|   .    ....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

PLDWAKKLQISCEVLQAVTFMHACNILHLDIKPANILVESATIRPYICDLGLAHIKNRNLMSQSAVNIRGTPCFMPPEALGATEPGYRHSN-KHDIWSVA
|  .|..  . .....|. ..|  .|.| |.||.|||. .   .  ||| ||| .            . ||| .|.|| |        ..  | |.||. 
PE-HARF--YMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL---------TTFCGTPWYMAPEVL-------GYGKCKCDWWSCG

GTLVELYSNKRLWGDSVHPLALMARILTGQMSKPESLTAVDSKVQKILEPCFRQKPEKRPAASDLLD---------QF
 .| |... . ..    .. ... .|.             .. .  ... |..  ||||| | ..|           |
CILYEMLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase TKL2.AA Pkinase 159-419 21 2.3e-41 147.33 Pfam 1-293 (293) Show / Hide 
Range on Protein: 159-419
Range on HMM: 1-293/293
Sequence Identity: 21% (66 aa)

LDMGPVVGKGQFGVVHRASWRGTP--VAVKKISMMGSRKDEIEK-----EVAIHRRACHPNIVQMMALGYQGREAFLVMQFIEGP----SLHTVIFPDRD
.  | ..|.| ||.| .. ..||.  ||||.|.  . .... .      |..|..| .|||||..    . ...  .|| . ||     .|...|     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

DVKIPL--DWAKKLQISCEVLQAVTFMHACNILHLDIKPANILVESATIRP----YICDLGLAHIKNRNLMSQSAVNIRGTPCFMPPEALGATEPGYRHS
. . ..  ..     .  ..|... ..|...|.| |.||.|||.   .  .     ||| |||  .. .  .. .  . ||| .|.|| .     |  ..
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIR---GGQYYG

NKHDIWSVAGTLVELYSNKRLWGDS-----VHPLALMARILTGQMSKPESLT------------------AVDSKVQKILEPCFRQKPEKRPAASDLLDQ
 | |.||.  .| |... . .. ..     . ......||. .. . ... .                  ....  ..... |....|.||| | ..|  
PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH

--F
  |
PWF
Kinase TKL2.AA STE 159-420 20 1.9e-29 101.22 In-house 1-359 (359) Show / Hide 
Range on Protein: 159-420
Range on HMM: 1-359/359
Sequence Identity: 20% (76 aa)

LDMGPVVGKGQFGVVHRASWR-----------------GTPVAVKKISMMGSR------------------KDEIEKEVAIHRRAC--HPNIVQMMALGY
..   ..||| ||.|..|  .                 |. .|.|....  ..                  ...|.||. |...    |||||.     .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

QGR-------EAFLVMQFIEGPSLHTVIF-----PDRDD------VKIPLDWAKKLQISCEVLQA-VTFMHACNILHLDIKPANILVESATIRPYICDLG
..        | ...| ...| ||  .|      .....       ..| .. ..  | ...|..   . |  .| | ||||||||.        .|| |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAY--ICRQILKGLLYYLHSHHIIHRDIKPANILL------VKLCDFG

LAHIKNRN--------------LMSQSAVNIRGTPCFMPPEALGATEPGYR---HSNKHDIWSVAGTLVELYSNKRLWGDSVHPLALMARILTGQMSK--
.. . . .               |.|    . ||| .| || .   . | |   .. | ||||.  |..|.   |  | |  .. |... .  . |.   
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQF

-------------PESLTAVD----------------SKVQKILEPCFRQKPEKRPAASDLLD---QFN
             |. |  ..                .. .  .. |..  |.||| ||.||     | 
EQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase TKL2.AA MOS 159-289 29 3.1e-25 80.46 In-house 1-147 (299) Show / Hide 
Range on Protein: 159-289
Range on HMM: 1-147/299
Sequence Identity: 29% (46 aa)

LDMGPVVGKGQFGVVHRASWRGTPVAVKKIS-----MMGSRKDEIEKEVAIHRRACHPNIVQMMALG---YQGRE--AFLVMQFIEGPSLHTVIF-----
  .  . |.| || |  | ..|.||||| .         .|.     || . .|. |.|||. ||..     . .  .. .| .  . .|| ||      
VCLCQMIGRGGFGSVWKAQYCGRPVAVKQVNKCTKNLKAMRR-SFWAEVNY-LRLRHDNIVRVMAVSQRSPEDFNNLGTIIMECGGNQTLHQVIYEPTRH

PD--------RDDVKIPLDWAKKLQISCEVLQAVTFMHACNILHLDIKPANILV
|         |      |  .. . .|  |. |... |..||||||.|||||.|
PPGDAGIIHCR-----MLILMHCCKYSLDVVNALQYCHHQNILHLDVKPANIIV
Kinase TKL2.AA TKL-Unique 161-361 24 9.5e-25 84.3 In-house 1-226 (290) Show / Hide 
Range on Protein: 161-361
Range on HMM: 1-226/290
Sequence Identity: 24% (55 aa)

MGPVVGKGQFGVVHRASWRGTPVAVKKISM-MGSRKDEIE---KEVAIHRRAC-HPNIVQMMALGY----QGREAFLVMQFIEGPSLHTVIF-----PDR
 . ..| | .|.| .. |||.|||.|...   .|......   .|| .  .   |||||. |.       .  . ..|| ...| ||. |.         
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

DDVKIPLDWAKKLQISCEVLQAVTFMHACN--ILHLDIKPANILVESA-TIRPY---ICDLGLAHIKNRNLMSQSA--------VNIRGTPCFMPPEALG
   ...|........   . |.  . | |.  |.|.|.|. |.|| .. .| ..   ||| ||. ...... . .         ... |..  |.|| | 
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRC-GSFRWMAPEVLR

ATEPGYRHSNKHDIWSVAGTLVELYSNKR
  .  .  |.| |..| .  | |....|.
MNF--CQYSEKSDVYSFGIVLWEIATRKI
Kinase TKL2.AA MLK 159-331 23 5e-24 80.33 In-house 1-205 (291) Show / Hide 
Range on Protein: 159-331
Range on HMM: 1-205/291
Sequence Identity: 23% (50 aa)

LDMGPVVGKGQFGVVHRASWRGTP-----VAVKKIS-------MMGSRKDEIEKEVAIHRRACHPN----IVQMMALGYQ-GREAFLVMQFIEGPSLHTV
..   ..|.| ||.|... ||..      ||||..         ... ....|.|. . |. .|||    |.| ..   | . . ..||...|| ||..|
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

I-----------FPDRDDVKIPLDWAKKLQISCEVLQAVTFMHACN---ILHLDIKPANILVES-----ATIRPYICDLGLAH-IKNR--NLMSQSAVNI
.            ... |. ...| |  ....  . ... . |.     | | |.|. |||.       .     ||| |... ....  | ||.     
LHGARSKWMDANHNQKNDRVYDHDHA--MNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSN-----

RGTPCFMPPEAL
.||. .| ||..
AGTYAWMAPEVI
Kinase TKL2.AA TK 159-419 13 9.4e-23 72.43 In-house 1-486 (486) Show / Hide 
Range on Protein: 159-419
Range on HMM: 1-486/486
Sequence Identity: 13% (67 aa)

LDMGPVVGKGQFG---VVHRASWRG---------------------------TPVAVKKIS--MMGSRKDEIE----------------KEVAIHR--RA
. .| . |.||||   .|... |||                           |||||| .      | .....                 | .. .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

CHPNIVQMMALGYQGRE------------AFLVMQFIEGPS----LHTVIFPDRDDVKI-----------------------------------------
 |||||.. .   ||..              .|| . .. .    |..     |.. .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------PLDWAKKLQISCEVLQAVTFMHAC------NILHLDIKPANILVESATIR----------PYICDLGLAH
                              .|. . .| ... . ..  ..|..      |. | |.   |.|| .  ..            |.| ||. 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

IKN----RNLM---SQSAVNIRGTPC-------------------------FMPPEALGATEPGYR-----HSNKHDIWSVAGTLVELYS-NKRLWGDSV
 .     | .       ... .||..                          |.||.|   ..        .. | |.||   .. |...  .  ..  .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

HP---------LALMARILTGQ-------------MSKPESLTAVD-------------SKVQKILEPCFRQKPEKRPAASDLLDQF
.            .| .. .|.             | .|    . |               .. ..  |.. .||.||  |.|..|.
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase TKL2.AA TAK1 159-330 27 1e-21 70.09 In-house 1-174 (284) Show / Hide 
Range on Protein: 159-330
Range on HMM: 1-174/284
Sequence Identity: 27% (51 aa)

LDMGPVVGKGQFGVVHRASWRGTPVAVKKISMM-----GSRKDEIEKEVAIHRRACHPNIVQMMAL-GYQGREAFLVMQFIEGPSLHTVIFPDRDDVKIP
 .   .|||| .||| .|.||.. .|||..  .     .. . .||.|.    |. ||||..   .    .  . ||| .... ||| ...  ..     
IQNEHFVGKGTYGVVCKAKWRNKEIAVKRFEFIKYSSEECEQKNIEREIMQWSRVDHPNIIKLYGMYACHRQCQCLVMEYMDCGSLHNFLHGAKPKWEYT

LDWAKK--LQISCEVLQAVTFMHACN---ILHLDIKPANILVESATIRPYICDLGLAHIKNRNLMSQSAVNIRGTPCFMPPEA
.. |    .|..    |.| ..|.     . | ||||.| |  .      ||| |..       |.|.  . |||. .| ||.
HAHAMSWMHQCA----QGVAYLHSMQPKPQIHRDIKPQNMLLCNKHRTLKICDFGTFCD-----MHQMMTCNRGTCRWMAPEV
Kinase TKL2.AA LISK-DD1 164-329 29 1.3e-21 75.09 In-house 1-201 (290) Show / Hide 
Range on Protein: 164-329
Range on HMM: 1-201/290
Sequence Identity: 29% (59 aa)

VVGKGQFGVVHRASWRGTPVAVKKISM--MGSRKDEIEK----EVAIHRR---ACHPNIVQMMALGYQ-------------GREAFLVMQFIEGPSLHTV
  ||| || | .... |||||.|||.     . ... .|    |... .      ||||||    ..              ... ..|  ||||  ||  
EIGKGSFGKVYKGCYFGTPVAIKKIHKQPNDPNDPDYWKFMQREIKMLKNLLNIRHPNIVQFIGICEHPLASPSLVNRLLNESSLYIVTEFIEGGDLHWY

IFP-DRDDV-------KIPLDWAKKLQISCEVLQAVTFMHACNILHLDIKPANILVESA---TIRPYICDLGLAHIKNRNLMSQSA--VNIRGTPCFMPP
..    ||        |||. | ... |.  . .|  . |. ||.| | |  ||||       .|  .||.|.| . .    .|      | ||. .|.|
LKNTPFDDTPEQYIHHKIPIPWKLRVKIALDIACAMAYLHSKNIIHRDLKSKNILVDENGDSQWRIKVCDFGFARMFEQKKNQQNNRHMTICGTDNWMAP

E
|
E
Kinase TKL2.AA TyrKc 159-419 19 1.3e-14 13.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 159-419
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

LDMGPVVGKGQFGVVHRASWRGTPVAVKKISMMGSRKDEIEKEVAIHRRA--CHPNIVQMMALGYQG-------REAFLVMQFIEGPSLHTVIFPDRDDV
. .| . | |.||.|... |. ..||||..      . .. .|  | ..    |||||.. .   |.          ..|| . .. .|.  .   |.. 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK-

KIPLDWAKKLQISCEVLQAVTFMHACNILHLDIKPANILVESATIRPYICDLGLAHIKNRN--------LMS-----QSA--VNIRGTPCFMPPEALGAT
   | ....|...  . .   . |  |. | |.   |.|| .   .  |.| ||.                .     ..   . ||     |.||..   
---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIR----WMAPECI---

EPGYRHSNKHDIWSVAGTLVELYSN-KRLWGDS----VHPLALMARILTG-QMSKPES-LTA-----VDSKVQKILEPCFRQKPEKRPAASDLLDQF
   .. . | |.||   .. |.... .  . .     . .  ..... .|  | .|.. .         ... .| . | . .||.||  |.. ..|
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase TKL2.AA CAMK 164-216 15 2.1e-14 42.13 In-house 1-103 (425) Show / Hide 
Range on Protein: 164-216
Range on HMM: 1-103/425
Sequence Identity: 15% (16 aa)

VVGKGQFGVVHRASWRGTP--------------VAVKKISM-----------------------------MGSRKDEIEKEVAIHRRAC-------HPNI
. |.|.||.|...  . |.              ||.| |.                               .. ......|..|...         ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQM
...
IKL
Kinase TKL2.AA Pkinase_Tyr 159-240 26 1.8e-13 46.24 Pfam 1-96 (270) Show / Hide 
Range on Protein: 159-240
Range on HMM: 1-96/270
Sequence Identity: 26% (25 aa)

LDMGPVVGKGQFGVVHRASWR------GTPVAVKKI--SMMGSR--KDEIEKEVAIHRRA-CHPNIVQMMALGY-QGRE--AFLVMQFIEGPSLHT
. .| . |.|.||.|... |.      ..|||||..  . | .   ...  .|..| .    |||||....  . ||.    ..|| . .. .|..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD
Kinase TKL2.AA CAMK 265-329 23 3.7e-13 38.02 In-house 188-290 (425) Show / Hide 
Range on Protein: 265-329
Range on HMM: 188-290/425
Sequence Identity: 23% (24 aa)

VLQAVTFMHACNILHLDIKPANILVESAT----------------IRPYICDLGLA--HIKNRNLM-------------------SQSAVNIRGTPCFMP
...|| ..| .|| |.|.|| |||. .                      |.| |.|   ... |..                    |      |||..|.
ICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMA

-PE
 ||
APE
Kinase TKL2.AA MLK 396-419 29 0.049455 3.0 In-house 268-291 (291) Show / Hide 
Range on Protein: 396-419
Range on HMM: 268-291/291
Sequence Identity: 29% (7 aa)

KILEPCFRQKPEKRPAASDLLDQF
| .. |  |.|.|||  .  . ..
KLMKQCWNQDPHKRPSFRQIVQHL
Kinase TKL2.AA Pkinase_Tyr 401-419 36 0.784912 3.44 Pfam 252-270 (270) Show / Hide 
Range on Protein: 401-419
Range on HMM: 252-270/270
Sequence Identity: 36% (7 aa)

CFRQKPEKRPAASDLLDQF
| ...||.||  |... |.
CWHYDPEDRPTFSEIHEQL