bon

Species: Fruit Fly
Alias: bon
External Links: Flybase Link
Annotation:

Classification

Group: Atypical
Family: TIF1

Sequence

Name Sequence Type Origin Length Description Download
bon.AA Protein None 1133 None Fasta, JSON

Protein domain

Protein domains of bon.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
RING bon.AA RING 83-130 22 7e-06 26.69 SMART 1-23 (23) Show / Hide
Range on Protein: 83-130
Range on HMM: 1-23/23
Sequence Identity: 22% (11 aa)

CVYCAQLLGSNDRPKLLECLHVACAQCVSTKFSELDRSLPPLIHCPVC
|  | .       |..|.| |  |  |.                ||.|
CPICLE-------PVVLPCGH-FCY-CI----------------CPIC

Zf-C3HC4 bon.AA zf-C3HC4 83-130 18 0.000701 12.27 Pfam 1-48 (48) Show / Hide
Range on Protein: 83-130
Range on HMM: 1-48/48
Sequence Identity: 18% (10 aa)

CVYCAQLLGSNDRPKLLECLHV-----ACAQCVSTKFSELDRSLPPLIHCPVC
|  | . .  . .| ...|.|       |  |... ... ... .    ||.|
CWICHCEWKDPNNPLIHPCGHRGSLKWFCHSCIKRWWNH-SGNTQ----CPIC

BBOX bon.AA BBOX 173-220 23 1.2e-08 36.01 SMART 1-51 (51) Show / Hide
Range on Protein: 173-220
Range on HMM: 1-51/51
Sequence Identity: 23% (12 aa)

AASIQCSSCSDGAVATSWC-VDCSEYICDSCVQA--HQRLKITKDHTIKPK
..   |... ....|. .| .||.. .|. | ..  ||. | ...|...| 
HRPPMCDNHQQHEPAHFFCVEDCQQCLCWDCDESGEHQANKLFRGHQVVPL

Zf-B_box bon.AA zf-B_box 174-220 25 8.2e-08 35.58 Pfam 1-45 (45) Show / Hide
Range on Protein: 174-220
Range on HMM: 1-45/45
Sequence Identity: 25% (12 aa)

ASIQCSSCSDGAVATSWCVDCSEYICDSCVQA-HQRLKITKDHTIKPK
    |. . .   .. .| ||.. ||..|... |.. . .|.||..| 
QM-YCPEHPE-EPLEYYCQDCQQCICEDCAVHGHKGNG-FKKHTVVPI

PHD bon.AA PHD 196-205 30 5.264573 1.61 Pfam 45-54 (54) Show / Hide
Range on Protein: 196-205
Range on HMM: 45-54/54
Sequence Identity: 30% (3 aa)

EYICDSCVQA
|..|..|. .
EWYCPRCKCC

BBOX bon.AA BBOX 235-276 29 6.3e-11 43.55 SMART 1-51 (51) Show / Hide
Range on Protein: 235-276
Range on HMM: 1-51/51
Sequence Identity: 29% (15 aa)

DKLHMCQLHP-QEKLSLFC-ETCDKLTCRDCQLS-DH------RDHKYKFA
..  ||. |   |.. .|| |.|... |.|| .| .|      |.|.... 
HRPPMCDNHQQHEPAHFFCVEDCQQCLCWDCDESGEHQANKLFRGHQVVPL

Zf-B_box bon.AA zf-B_box 236-276 26 4.4e-10 44.57 Pfam 1-45 (45) Show / Hide
Range on Protein: 236-276
Range on HMM: 1-45/45
Sequence Identity: 26% (12 aa)

KLHMCQLHPQEKLSLFCETCDKLTCRDCQLSDHRD-----HKYKFA
.  .|..||.|.|...|..|... |.|| ...|..     |...  
QM-YCPEHPEEPLEYYCQDCQQCICEDCAVHGHKGNGFKKHTVVPI

BBC bon.AA BBC 283-409 26 1.4e-42 148.72 SMART 1-132 (132) Show / Hide
Range on Protein: 283-409
Range on HMM: 1-132/132
Sequence Identity: 26% (35 aa)

SRQALSTLVSEINYKRFLLSSATKVIDDRQQLIH-----DKKKDLIKEITAMAVKITNTVNTRGKQLIMRLNEVCDSKLKVLVEKKETLQLLSDNTDHCI
 |..|.........|.. ...|.| |....| ..     ....|  ..|.|.  .. |..|.|.|...|.|.|.|. |.|.| ....|.. ......||.
HREKLEQHLTKLRKKHWECEDAMKQIQNIIQQVQPGHVDENHEDVEQCIRAHFDDLMNWLNRRKKMMLMDLDEQCENKQKWLMQQMQTMTQKQEQLEHCC

DFMQNALEKGSDFAILSSKKSLVRHLQKLKCQ
.|.|.||..|.....|.|||........|..|
QFCQWALNMGDCTEFLQSKKLIIFQCCHLHKQ

PHD bon.AA PHD 899-946 33 1e-14 47.54 Pfam 1-54 (54) Show / Hide
Range on Protein: 899-946
Range on HMM: 1-54/54
Sequence Identity: 33% (19 aa)

WCAVCLD-----GGELMCCD-KCPKVFHQNCHIPAIS--SLPDESESWQCLLCVNI
.|.|| .     .|...||| .||. ||| || | ..   .|..   |.|  |.. 
YCCVCQKCDWDDDGDMICCDNGCPRWFHQYCHGPPLEPEEIPEG--EWYCPRCKCC

PHD bon.AA PHD 899-944 29 3.2e-12 47.83 SMART 1-39 (39) Show / Hide
Range on Protein: 899-944
Range on HMM: 1-39/39
Sequence Identity: 29% (14 aa)

WCAVCLDGGELMCCD-KCPKVFHQNCHIPAISSLPDESESWQCLLCV
.| || . | ...|| .|.. .|| |. |. .   .... |.|  |.
YC-VCGK-G-MIQCDPGCDRWYHQ-CLGPPLE---PPDG-WYCPRCR

RING bon.AA RING 900-943 18 0.014736 4.35 SMART 1-23 (23) Show / Hide
Range on Protein: 900-943
Range on HMM: 1-23/23
Sequence Identity: 18% (8 aa)

CAVCLDGGELMCCDKCPKVFHQNCHIPAISSLPDESESWQCLLC
|..||.    ... .|   |.. |                | .|
CPICLE----PVVLPCGH-FCY-CI---------------CPIC

BROMO bon.AA BROMO 964-1071 24 2.9e-20 74.56 SMART 1-118 (118) Show / Hide
Range on Protein: 964-1071
Range on HMM: 1-118/118
Sequence Identity: 24% (30 aa)

SALELRILQRICLELYCQYEQS-----------LNFREPESPA---NTSYYEIVSSPMSLDVIRTRLDPSSPNHYKDIAGFVSDVRLIFSNTYLFYQEDT
.   .. .|... |..|. ...             |..| ..       ||.|.  ||.|. |. .|.    ..|...  || |..|.|.| . .. .|.
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLE---NHQYQSMEEFVDDFMLMFNNCMTYNEPDS

KTYSNAKYLENFFEEQLAKWLP
  |. || |..||||....  |
EVYKMAKKLQKFFEEKWREFPP

Bromodomain bon.AA Bromodomain 971-1057 23 2.1e-17 59.02 Pfam 1-89 (89) Show / Hide
Range on Protein: 971-1057
Range on HMM: 1-89/89
Sequence Identity: 23% (22 aa)

LQRICL--ELYCQYEQSLNFREP---ESPANTSYYEIVSSPMSLDVIRTRLDPSSPNHYK-DIAGFVSDVRLIFSNTYLFYQEDTKTYSNAKY
...|.   ... .   . .|..|   .   .. ||.|.. ||.|. |. .|     |.|.  ||.|  |..|...| . .. .|.  |  |..
CDQIMDMKYIMEHP-ICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKL---KNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK