Gene HMTK07 (M.brevicollis)

HMTK07

Species: M.brevicollis
Alias: HMTK07
External Links:
Annotation:

Classification

Group: TK
Family: HMTK

Sequence

Name Sequence Type Origin Length Description Download
HMTK07.AA Protein None 1017 None Fasta, JSON
HMTK07.kin_dom Protein Kinase Domain None 271 None Fasta, JSON

Protein domain

Protein domains of HMTK07.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PID HMTK07.AA PID 27-128 12 0.003618 12.91 Pfam 1-133 (153) Show / Hide 
Range on Protein: 27-128
Range on HMM: 1-133/153
Sequence Identity: 12% (17 aa)

FEAKFHGQLPVSRP-------QGNDVVMHAVSKIHEL---------------KQRAIPVQIMLTTKGVYVDQKDD---NSLMCKVPVAQLSWVCT--DPR
||... | ..| ..        . ...  .......                .|   .. . ..|.|| .  ...   ...|   |.  .| .    ||.
FEVRYLGCVEVPCHMRRPDKNTRMMQCQECIHRVCMQVPAKKINKIRGHRGHWQHWQKIDLHISTDGVKWIDEKTEAEQECMHDHPMRNISFCADGGDPH

-NKHLFSF-LVHEPRLHTVECYTFSSKK--NGK
 ..  |..  .......   |. | ..|  ...
VDMRYFAYDICRDGPCQRFACHVFWCCKTQQAQ
PTB HMTK07.AA PTB 218-347 14 0.000415 8.68 SMART 1-156 (156) Show / Hide 
Range on Protein: 218-347
Range on HMM: 1-156/156
Sequence Identity: 14% (23 aa)

SSLGCFKAIYKGGIPVKEIE-------GFHTVQQAALRVKDFGLPPKEVTLVVTQAQLILVERDTGDHMHEINMLHVSYSLVDP-----------RDHSH
..  ||.. | | ..|..         |   .|..  ... .. ......| ..   . |. ..|.. .|. .. ..|.. .||           .|...
PWGCCFNVWYLGCVEVPHHRNSMAPGKGMQVCQECMRKIRQHWKHWQKMHLHISVDGVKLIDPQTKQVIHHHPIHRISFCAHDPYRWNTGGHHCCDDDRC

FYWIVNDPRMG-------FAYCHIVQLLGNA-EMLPTCMAAAQRAVARHRRELASQ
| .|. .|             ||. .    . | .. .. .|   ... .    .|
FGYICRHPNDRGSHRMTYWFRCHVFWCEDPHAEDIAQTIGQAFQVCYQQCQKQRCQ
PID HMTK07.AA PID 255-316 20 0.014068 10.84 Pfam 55-123 (153) Show / Hide 
Range on Protein: 255-316
Range on HMM: 55-123/153
Sequence Identity: 20% (14 aa)

PPKEVTLVVTQAQLILVERDT---GDHMHEINMLHVSYSLV--DPR-DHSHFYW-IVNDPRMGFAYCHI
......| .. . . ..  .|   .. ||. .| ..|.  .  ||. |.  |   |. |.. .  .||.
HWQKIDLHISTDGVKWIDEKTEAEQECMHDHPMRNISFCADGGDPHVDMRYFAYDICRDGPCQRFACHV
PTB HMTK07.AA PTB 367-517 18 2e-14 55.18 SMART 1-156 (156) Show / Hide 
Range on Protein: 367-517
Range on HMM: 1-156/156
Sequence Identity: 18% (31 aa)

PPLGVYEVKYLGGVRCDGAG--------NEVVRKALGDLRQQFQQMLQLGDVQDWTQAGDRVVLVMTADGIRVVDLMSGEVLFFVYIRDVAFSTHL----
|.   ..|.||| |  . .         ..|.....  .|               .... ...|  . ||....|  ...|. .  |. ..|. |     
PWGCCFNVWYLGCVEVPHHRNSMAPGKGMQVCQECMRKIR-------------QHWKHWQKMHLHISVDGVKLIDPQTKQVIHHHPIHRISFCAHDPYRW

-HSGVDRKNNPEHDVFGFVAQDEKLN-------RHVCHLFKCPPGMARDICRTAAFAFKMCIEEMQRTEQE
   | . .... ...||... ..          .. ||.|.| .  | ||..|.  ||. | .. |.  ..
NT-GGH-HCCDDDRCFGYICRHPNDRGSHRMTYWFRCHVFWCEDPHAEDIAQTIGQAFQVCYQQCQKQRCQ
PID HMTK07.AA PID 372-514 20 1.1e-07 28.72 Pfam 1-153 (153) Show / Hide 
Range on Protein: 372-514
Range on HMM: 1-153/153
Sequence Identity: 20% (33 aa)

YEVKYLGG--VRCD-GAGNEV-----VRKALGDLRQQFQQMLQLGDVQDWT---QAGDRVVLVMTADGIRVVDLMS---GEVLFFVYIRDVAFSTH-LHS
.||.|||   | |  ... .      .. ..  ...|.     ...... .   |.. ...|  . ||....| ..   .|.. .  .| . |  .  ..
FEVRYLGCVEVPCHMRRPDKNTRMMQCQECIHRVCMQVP-AKKINKIRGHRGHWQHWQKIDLHISTDGVKWIDEKTEAEQECMHDHPMRNISFCADGGDP

GVDRKNNPEHDVFGF-VAQDEKLNRHVCHLFKCPP-GMARDICRTAAFAFKMCIEEMQRT
 ||      .. |.. .. | ...|. || |.| . . |.|| .|   ||  | .. .| 
HVD------MRYFAYDICRDGPCQRFACHVFWCCKTQQAQDIAQTVGQAFQVCYQQCLRA
Kinase HMTK07.AA HMTK 545-812 50 1.2e-191 642.94 In-house 1-291 (291) Show / Hide 
Range on Protein: 545-812
Range on HMM: 1-291/291
Sequence Identity: 50% (147 aa)

IKAIKVLGSGQFG-----------------TVWLALQR---MRDSSSSKAVKHRAVKLLRPNASEQDQEDFLREAITMSRISHPNLVRLVGVSVNHVPWL
.|||||.|.||||                 .|.||...   ......|....|||||.||..||..|.|.|||||..|....|||||.||||.....|||
LKAIKVIGAGQFGMVQCLRLAPPDEGCTSLKVYLAEWSVKDGDGKDDSNQPHHRAVKMLRGDASHEDREEFLREAEVMCQLRHPNLVQLVGVCMQQRPWL

VVLEFMRYGDLRNLLIACSEKKIEVTLAEQLQFMQSVCSGMAYLASKRLVHMDLACRNCLVGSNSQLKIGDFGLTRPFDEGKNYYKLEPNSSVKLPAKWL
.|||.|.||||||.|..|.||.|..|..|||.|.....|||||.||.|.||||||.||||||.|.|.||.||||||..|.|..|..|.... ||||.||.
CVLEYMQYGDLRNVLKTCREKNIQLTYHEQLYFCVQCASGMAYIASQRMVHMDLAARNCLVGHNNQVKIADFGLTRRLDPGQDYWHLRKHM-VKLPIKWM

SVEALS--TMTFSEKSDVWAAGVVFWEIVTYGSQPYP--QFRNKEMRRKLKEGYRLEQPTDFACPTDLYELMTLAWEADPDRRICFADLGIK
..||..  ...|||||||||.||..|||..||.|||.  |..|||..|...||.||.||....||.|...||. .|..||..|..||.|...
APEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGEQPYESQQIKNKEVQRHVREGRRLTQPPPDDCPDDFWDLMCTCWHKDPHQRPTFAQLQKM
Kinase HMTK07.AA TK 545-813 22 1.5e-103 348.1 In-house 1-486 (486) Show / Hide 
Range on Protein: 545-813
Range on HMM: 1-486/486
Sequence Identity: 22% (110 aa)

IKAIKVLGSGQFG---TVWLALQRMRDS------------------SSSKAVKHRAVKLLRPNASEQDQE-------------DFLREAITMSRIS----
|. .|.||.||||   .|.... |.|.                   ......   ||| |.. ......|             |||.||  |.  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPNLVRLVGVSVNHVP------------WLVVLEFMRYGD----LRNLLIACSEKKIE-----------------------------------------
 |||.|||.||.. ..|            |..|.|.| .||    ||. | .|..|...                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------VTLAEQLQFMQSVCSGMAYLASK------RLVHMDLACRNCLVGSNSQ-----------LKIGDFG---
                               .|....| ... ...||.||.||      ..||.|||.||||||.| .            ||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LTRPFDEGKNYYKLEPNS---------------------SVKLPAKWLSVEALS---------TMTFSEKSDVWAAGVVFWEIVTYG-SQPYPQF
     |.|  .....||. .. .                     . ||| .|.. |.|          . .|..|||||. ||. |||.|||  ..|.. 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

RN---------KEMRRKLKE------------GYRLEQPTDFACP--------------TDLYELMTLAWEADPDRRICFADLGIKV
 |         .|. ..|..            |||...|    ||              ...|.||.  |..||..|  |..|  . 
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase HMTK07.AA Pkinase_Tyr 545-816 38 5.2e-102 346.12 Pfam 1-270 (270) Show / Hide 
Range on Protein: 545-816
Range on HMM: 1-270/270
Sequence Identity: 38% (107 aa)

IKAIKVLGSGQFGTVWLALQRMRDSSSSKAVKHRAVKLLRPNASEQD--QEDFLREAITMSRI-SHPNLVRLVGVSV-NHVP--WLVVLEFMRYGDLRNL
|. .|.||.|.||.|...  ..   . ..   . ||| |...|....  .|||.||| .|. . .|||.|||.|| .    |  ...|.|.| .|||.. 
ITFGKKLGEGAFGEVYKGTWKG---DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

LIACSEKKIEVTLAEQLQFMQSVCSGMAYLASKRLVHMDLACRNCLVGSNSQLKIGDFGLTRPFDEGKNYYKLEPNSSVKLPAKWLSVEALSTMTFSEKS
| . .| |  .|. . ||. . ...||.||.||...| |||.|||||..| . ||.||||.|   . . || .   .. ||| ||.. |..... |..||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKS

DVWAAGVVFWEIVTYGSQP-YPQFRNKEMRRKL-KEGYRLEQPTDFACPTDLYELMTLAWEADPDRRICFADLGIKVQAL
|||. ||. |||.||| || ||   | |. ... ..|||...| .  || ..|.||.. |..||..|  |...   .. |
DVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN--CPDEIYDLMKQCWHYDPEDRPTFSEI---HEQL
Kinase HMTK07.AA TyrKc 545-816 35 9.7e-95 321.96 SMART 1-280 (280) Show / Hide 
Range on Protein: 545-816
Range on HMM: 1-280/280
Sequence Identity: 35% (107 aa)

IKAIKVLGSGQFGTVWLALQRMRDSSSSKAVKHRAVKLLRPNASEQDQEDFLREAITMSRI--SHPNLVRLVGVSVNH-------VPWLVVLEFMRYGDL
|. .|.||.|.||.|...  .         |   ||| |...|    .|||.|||  |...  .|||.|||.|| . .        | ..|.|.| .|||
ITLGKKLGEGAFGEVYKGTWK-------IQV---AVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

RNLLIACSEKKIEVTLAEQLQFMQSVCSGMAYLASKRLVHMDLACRNCLVGSNSQLKIGDFGLTRPFDEG------KNYYKLEPNSSVK--LPAKWLSVE
.. | .. .|   ..... |.|.  ...||.||.||...| |||.||||||.| . ||.||||.|  ...      | ||.    .. |  || .|.. |
KDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

ALSTMTFSEKSDVWAAGVVFWEIVTYGSQPYPQ-----FRNKEMRRKLKEGYRLEQPTDFA------CPTDLYELMTLAWEADPDRRICFADLGIKVQAL
.. . .|..|||||. ||. ||| ||| ||||        |.|.....|.|||..|| .        ||...|..|.  |..||. | .|...   .. .
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF
Kinase HMTK07.AA UTK 545-813 34 6e-74 251.98 In-house 1-296 (296) Show / Hide 
Range on Protein: 545-813
Range on HMM: 1-296/296
Sequence Identity: 34% (104 aa)

IKAIKVLGSGQFGTVWLALQRMRDSSSSKAVKHRAVKLLRPNAS-EQDQE---DFLREAI---TMSRIS-HPNLVRLVGVSVNHVPWLVVLEFMRYGDLR
..  . ||.|.||.| .|  | .. |    . ..||| ... |. .|..|   ||..||     |.. . |||..||||| ..  ||..|.|.|. ||||
VQLGRQLGQGAFGEVHKA--RFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLR

NLLIACSEKKI----EVTLAEQLQFMQSVCSGMAYLASKRLVHMDLACRNCLVGSN-------SQLKIGDFG---LTRPFDE--------GKNYYKLEPN
..|  ....       .|| ..|...  . .||.||.|...|| |||.|||||...       .. ||.|||   ..|            . .||.  ..
SYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQ

SSVKLPAKWLSVEALSTM-TFSEKSDVWAAGVVFWEIVTYGSQPYPQFRNKEMRRKLKEG--YRLEQPTDFACPTDLYELMTLAWEADPDRRICFADLGI
   ..| .| . |||  . .|..|||||. ||| |||.|.|..|||   | .    . .|  ||...| |  || ..|.||.  |..||..|  | ||  
--DRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWD--CPHPVYRLMHRCWHYDPQERPDFEDLVQ

KV
..
QM
Kinase HMTK07.AA TK-Unique 545-803 30 2.1e-72 246.82 In-house 1-284 (294) Show / Hide 
Range on Protein: 545-803
Range on HMM: 1-284/294
Sequence Identity: 30% (88 aa)

IKAIKVLGSGQFGTVWLALQRMRDSSSSKAVKHRAVKLLRPNASEQDQEDFLREAITMSRIS-HPNLVRLVGVSVNHV-PWLVVLEFMRYGDLRNLLIAC
..  .|.|.|.||.|| .  . ..  .. . |. |||.|. ||...|. |||.|.  |. .  |||.|...|...    ||. ..|....|.|...|  |
LEVGDVIGEGAFGQVWRGEVWGIW-KHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTC

S-------------------EKKIE---VTLAEQLQFMQSVCSGMAYLAS--KRLVHMDLACRNCLVGSNSQLKIGDFGLTRPFDEGKNYYKLEPNSSVK
                    ..| .   ...   ..|.  ...||.||||  |. ||.||. ||.|.... ..||.|||..|  . .. | . .  |. .
RPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMC--SQGR

LPAKWLSVEALS--TMTF-SEKSDVWAAGVVFWEIVTYGSQPYPQFRNKEMRRKLKEGYRLEQPTDFAC-PTDLYELMTLAWEADPDRR
.| .|.. |.|.  . .. ..|||||. ||. |||.|.|..|||. ..|........|||..||    | . ..|.||   |  .|. |
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPE--HCCSHEMYNLMKSCWQWEPEER
Kinase HMTK07.AA Src 545-813 37 3.4e-69 234.21 In-house 1-255 (255) Show / Hide 
Range on Protein: 545-813
Range on HMM: 1-255/255
Sequence Identity: 37% (100 aa)

IKAIKVLGSGQFGTVWLALQRMRDSSSSKAVKHRAVKLLRPNASEQDQEDFLREAITMSRISHPNLVRLVGVSVNHVPWLVVLEFMRYGDLRNLLIACSE
|| .. ||.|||| || .. .      .  |   ||| |.|     ..|.||.|| .|   .|..||.|  |     | . | |.|. | |   | . ..
IKLCRKLGQGQFGEVWMGYWNG-----NTKV---AVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-DG

KKIEVTLAEQLQFMQSVCSGMAYLASKRLVHMDLACRNCLVGSNSQLKIGDFGLTRPFDEGKNYYKLEPNSSVKLPAKWLSVEALSTMTFSEKSDVWAAG
.  .. | ... .   | .||||| |....| ||| || ||| |.  |..|||| | ..|... |  .. .  |.| ||   ||..  .|. |||||  |
EGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEY--CARHGAKFPIKWTAPEAINYGRFTIKSDVWSFG

VVFWEIVTYGSQPYPQFRNKEMRRKLKEGYRLEQPTDFACPTDLYE-LMTLAWEADPDRRICFADLGIKV
.  .||||||  |||  .|.|  .... |||. .|.   ||  ||| .|.  |..||..| .|. |  . 
ILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN--CPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase HMTK07.AA CTKA 545-813 34 1.8e-67 225.76 In-house 1-290 (290) Show / Hide 
Range on Protein: 545-813
Range on HMM: 1-290/290
Sequence Identity: 34% (101 aa)

IKAIKVLGSGQFGTVWLALQRMRDS---SSSKAVKHRAVKLLRPNASEQDQEDFLREAITMS--RISHPNLVRLVGVSVNHVPWLVVLEFMRYGDLRNLL
      .|.|..| |  |. . .        |  |  ||| |. .| | | . || || . |    .||| .||.||   | ||. . |.| ||||.  |
HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKDVAVKMLKDHATEEDRRAFLHEAFVLSSEHFHHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCYL

IACSEKK------------------IEVTLAEQLQFMQSVCSGMAYLASKRLVHMDLACRNCLVGSNSQLKIGDFGLTRPFDEGKNYYKLEPNSSVKLPA
 ||                      |||   ||      .  || |||.  .|| ||||||||.|.    || |||. |  . .  || .   |.  .| 
RACRPADGQVCPARARRSIPRSFHPIEVHAHEQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQYCHIKIADFGHGRTLRTESQYYYVS--SQRVMPV

KWLSVEALSTMTFSEKSDVWAAGVVFWEIVTYGSQPYPQFRNKEMRRKLKEG--YRLEQPTDFACPTDLYELMTLAWEADPDRRICFADLGIKV
 | . ||| . .||  ||||| ||. ||| . |  |.     .|       .   ||  |    ||  || .|.. |   |  |  |. |    
RWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAYTSHGMRRLPVPR--NCPQVLYHCMQECWKFEPNQRPTFETLQRML
Kinase HMTK07.AA Abl 545-813 37 1.3e-65 217.67 In-house 1-252 (252) Show / Hide 
Range on Protein: 545-813
Range on HMM: 1-252/252
Sequence Identity: 37% (102 aa)

IKAIKVLGSGQFGTVWLALQRMRDSSSSKAVKHRAVKLLRPNASEQDQEDFLREAITMSRISHPNLVRLVGVSVNHVPWLVVLEFMRYGDLRNLLIACSE
|   . || ||.| |. .. .  |    . |   ||| |. .. |   ..||.||  |  . |||||.|.||     |. .. ||| || | . |  |..
IMMKHKLGGGQYGEVYEGVWKRHD----CTV---AVKTLKEDTME--VHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLRECDR

KKIE-VTLAEQLQFMQSVCSGMAYLASKRLVHMDLACRNCLVGSNSQLKIGDFGLTRPFDEGKNYYKLEPNSSVKLPAKWLSVEALSTMTFSEKSDVWAA
.... |.|   |.    . ||| || ..  .| ||| |||||| .  .|. ||||.| . ..  |         | | ||   |.|   .|| |||||| 
EELPAVVL---LYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLAR-MMKDDTYTA---HAGAKFPIKWTAPESLAYNKFSSKSDVWAF

GVVFWEIVTYGSQPYPQFRNKEMRRKLKEGYRLEQPTDFACPTDLYELMTLAWEADPDRRICFADLGIKV
||. ||| |||  |||    ...  || .|||.|.|    ||.. ||||   |. ..  |  |...  ..
GVLLWEIATYGMSPYPGIDLSHVYHKLEKGYRMERPE--GCPPKVYELMRQCWQWSHTDRPSFKEIHHAM
Kinase HMTK07.AA Axl 545-811 36 3.3e-64 219.64 In-house 1-267 (267) Show / Hide 
Range on Protein: 545-811
Range on HMM: 1-267/267
Sequence Identity: 36% (100 aa)

IKAIKVLGSGQFGTVWLALQRMRDSSSSKAVKHRAVKLLR-PNASEQDQEDFLREAITMSRISHPNLVRLVGVSVNHVP------WLVVLEFMRYGDLRN
.   |.|| | ||.|  .  .  | |. |     ||| ..  . .... |.||.||. |   .||| .||.||...          .|.| ||..|||  
FVLGKMLGEGEFGSVMEGQLKQEDGSFVKV----AVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQMSERQRIPKPMVILPFMKHGDLHT

LLIAC--SEKKIEVTLAEQLQFMQSVCSGMAYLASKRLVHMDLACRNCLVGSNSQLKIGDFGLTRPFDEGKNYYKLEPNSSVKLPAKWLSVEALSTMTFS
 |..    .. . . |   ..||  . .|| ||.... .| ||| |||..  .    . |||| .   .|  ||.    .  |.| ||. .|.|    . 
FLLYSRLGDQPFYLPLQMLVKFMVDIACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSG-DYYRQGCIA--KMPVKWIAIESLADRVYT

EKSDVWAAGVVFWEIVTYGSQPYPQFRNKEMRRKLKEGYRLEQPTDFACPTDLYELMTLAWEADPDRRICFADLGI
 |||||| ||  |||.| |  |||   |.||   | .| || || |  |  .||.||   |||||  |  |. |  
SKSDVWAFGVTMWEIMTRGQTPYPGVENHEMYDYLIHGHRLKQPED--CMDELYDLMYQCWEADPKDRPSFSVLRE
Kinase HMTK07.AA Frk 545-817 37 1.2e-63 217.82 In-house 1-260 (260) Show / Hide 
Range on Protein: 545-817
Range on HMM: 1-260/260
Sequence Identity: 37% (104 aa)

IKAIKVLGSGQFGTVWLALQRMRDSSSSKAVKHRAVKLLRPNASEQDQEDFLREAITMSRISHPNLVRLVGVSVNHVPWLVVLEFMRYGDLRNLLIACSE
|. |. ||||||| ||  |               ||| |.| .   | .||||||  | .. || |..|  |     | ... | || | | . | | ..
IQLIRRLGSGQFGEVWEGLWNN--------TTPVAVKTLKPGT--MDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAIND

KKIEVTLAEQLQFMQSVCSGMAYLASKRLVHMDLACRNCLVGSNSQLKIGDFGLTR-PFDEGKNYYKLEPNSSVKLPAKWLSVEALSTMTFSEKSDVWAA
|  .. . ....    | .||||| |.  .| ||| || ||| .  .|| |||| |    . .. |  |    ...| ||   ||  .  |. |||||. 
KGRQCQMQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIY--ESRHGARFPIKWTAPEAANYNKFTIKSDVWSF

GVVFWEIVTYGSQPYPQFRNKEMRRKLKEGYRLEQPTDFACPTDLYELMTLAWEADPDRRICFADLGIKVQALL
|..  ||.|||  |||   |.|.   ...|||. ||.   ||  |||.|   |..||..|  |  |  |..  .
GILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPP--NCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF
Kinase HMTK07.AA Fer 545-814 29 2.2e-63 214.71 In-house 1-283 (283) Show / Hide 
Range on Protein: 545-814
Range on HMM: 1-283/283
Sequence Identity: 29% (87 aa)

IKAIKVLGSGQFGTVWLA---LQRMRDSSSSK---AVKHRAVKLLRPN-ASEQDQEDFLREAITMSR-ISHPNLVRLVGVSVNHVPWLVVLEFMRYGDLR
.. .|.||.| ||.|...   | .... .. .   ||   .|| .. . |..  ...|..||  |    .||| |.. ||.|   | ..|.||.  |.|.
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAV---KVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLD

NLLIACSEKKIE--VTLAEQLQFMQSVCSGMAYLASKRLVHMDLACRNCLVGS-NSQLK--IGDFGLTRPFDEGKNYYKLEPNSSVKLPAKWLSVEALST
. |     |. .  |...| ...   ...||.|| ||  .| |.| ||||..  . ..|  | |||. |  ..... ||. .  . |.| .||. |...|
SYLK----KNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKE-KACKVPIRWLAPETWQT

MTFSEKSDVWAAGVVFWEIVTYGSQPYPQ----FRNKEM-----RRKLKEGYRLEQPTDFACPTDLYELMT-LAWEADPDRRICFADLGIKVQ
...|.|.|||. ||. ||| | | .|||     ......     ... |.||..  |    .|......|.   |..||. |. ....  |. 
GIYSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNH--MPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase HMTK07.AA S_TKc 545-817 18 3.9e-38 133.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 545-817
Range on HMM: 1-231/231
Sequence Identity: 18% (53 aa)

IKAIKVLGSGQFGTVWLALQRMRDSSSSKAVKHRAVKLLRPNASEQDQEDFLREAITMSRISHPNLVRLVGVSVNHVPWLVVLEFMRY--GDLRNLLIAC
 . ....|.| ||.|...  .          .. |.| ..        |...||   ...  |||.|.| .| ..     .|.|..    |||. ..  .
YEILRKIGKGAFGKVYKCRHKK-------TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR

SEKKIE--VTLAEQLQFMQSVCSGMAYLASKRLVHMDLACRNCLVGSNSQLKIGDFGLTRPFDEGKNYYKLEPNSSVKLPAKWLSVEALSTMTFSE-KSD
  ..     .  .   .|. .|....|. |.. .| ||   | |. .  ..||.|||| | .            ...     ... | |    ..  |.|
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------TTFCGTPWYMAPEVL---GYGKCKCD

VWAAGVVFWEIVTYGSQPYPQFRNKEMRRKLKEGYRLEQPTDFACPTDLYELMTLAWEADPDRRICFADLGI-----KVQALL
.|. |....| .. |  |.|    ..| .|..             . .. ...   .. ||..|.   ..       |    .
WWSCGCILYEMLC-GYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase HMTK07.AA Pkinase 545-804 20 8e-22 78.25 Pfam 1-282 (293) Show / Hide 
Range on Protein: 545-804
Range on HMM: 1-282/293
Sequence Identity: 20% (60 aa)

IKAIKVLGSGQFGTVWLALQRMRDSSSSKAVKHRAVKLLRP--NASEQDQEDFL-REAITMSRISHPNLVRLVGVSVNHVPWLVVLEFMRYG----DLRN
.. ....||| ||.|...  .             ||| ..   . |..||.... .|.  | |..||| ||| ..  ..    .|.|... |    ||  
YHIGRKIGSGSFGCVYKCHHKGTGK-------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFD

LLIACSEKKIEV--TLAEQLQFMQSVCSGMAYLASKRLVHMDLACRNCLVGSNSQL----KIGDFGLTRPFDEGKNYYKLEPNSSVKLPAKWLSVEALS-
.. .  ...  .  .  |   .|  ...|..|. |.. .| ||   |.|. .| ..    ||.|||| . ||    | . . ....     ... | .  
YIST--WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIRG

TMTFSEKSDVWAAGVVFWEIVTYGSQPYPQF-------RNKEMRRKLKEGYRLEQPTDFACP-----------------TDLYELMTLAWEADPDRRI
    . |.|.|..|....| .. |  |.|.         .. ..|...  .. . |..   .                  .. ....  .. || .|.
GQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP