Gene RTKB3 (M.brevicollis)

RTKB3

Species: M.brevicollis
Alias: RTKB3
External Links:
Annotation:

Classification

Group: TK
Family: RTKB

Sequence

Name Sequence Type Origin Length Description Download
RTKB3.AA Protein None 1859 None Fasta, JSON
RTKB3.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of RTKB3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HYR RTKB3.AA HYR 529-606 29 9.4e-05 17.68 Pfam 1-86 (86) Show / Hide 
Range on Protein: 529-606
Range on HMM: 1-86/86
Sequence Identity: 29% (25 aa)

VDVTPPELTLAPNA---IVRFEALTNTFVYPTVTATDTSG-ERIVVTHTNNVQPD--EVG-TYDVTYSGEDSAKNKG-VLVVQVII
|| |||  .  ||     | .. .|    ....||||.||   .... ... . |   || ...|||  .|.| |..   ...| .
VDTTPPTVENCPNNIFRTVELGTSTVNVFWTEPTATDNSGDIQANLISRTAQPGDFFPVGEQTTVTYTFQDNAGNQADTCTFTVTV
GCC2_GCC3 RTKB3.AA GCC2_GCC3 406-444 35 0.001647 14.38 Pfam 1-37 (49) Show / Hide 
Range on Protein: 406-444
Range on HMM: 1-37/49
Sequence Identity: 35% (15 aa)

GTFHNTVR--CLSCGSGTYQDSASHLSTSCKTKSRCPAG-TY
||..|.    | .|. ||||.... .  ||.    ||.| |.
GTYYNKGQNPCEPCPRGTYQNEEGQD--SCI---PCPPGKTT
GCC2_GCC3 RTKB3.AA GCC2_GCC3 448-477 29 0.004375 13.0 Pfam 1-29 (49) Show / Hide 
Range on Protein: 448-477
Range on HMM: 1-29/49
Sequence Identity: 29% (9 aa)

GGSSSSNT-NCLACPAGSYQDATNHLETSCK
|  ..... .| .|| |.||.  . .  ||.
GTYYNKGQNPCEPCPRGTYQNEEGQD--SCI
TNFR RTKB3.AA TNFR 460-501 26 0.007584 15.72 SMART 1-50 (50) Show / Hide 
Range on Protein: 460-501
Range on HMM: 1-50/50
Sequence Identity: 26% (13 aa)

CP--AGSYQDATNHLE--TSCKTKT-NTCPV---GHYASNGGSTTSDRIC
|.  .| |..  ||.     |.  .  .||    |.|..  .. ||...|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC
TNFR RTKB3.AA TNFR 417-457 27 0.019319 11.47 SMART 1-50 (50) Show / Hide 
Range on Protein: 417-457
Range on HMM: 1-50/50
Sequence Identity: 27% (14 aa)

CG--SGTYQDSASHL---S--TSCKTKSRCPA---GTYDANGGSSSSNTNC
|    |.|... .|.   .  ..|   .|||    |.|    ... ||| |
CKCQEGHYCHHWNHTHYEPHCLPCR-HTRCPPEHMGQYMKQPCTATSNTVC
GCC2_GCC3 RTKB3.AA GCC2_GCC3 486-529 31 17.30604 1.3 Pfam 1-33 (49) Show / Hide 
Range on Protein: 486-529
Range on HMM: 1-33/49
Sequence Identity: 31% (14 aa)

GHYASNGGSTTSDRICAVCPDACDLSHGAYQDQTGQTSCDGCGV
|.| ..|.      .|  ||      .| ||.. ||.||  |..
GTYYNKGQ-----NPCEPCP------RGTYQNEEGQDSCIPCPP
HYR RTKB3.AA HYR 691-701 66 0.344112 5.94 Pfam 1-12 (86) Show / Hide 
Range on Protein: 691-701
Range on HMM: 1-12/86
Sequence Identity: 66% (8 aa)

VDTTPPGV-NVT
|||||| | |..
VDTTPPTVENCP
HYR RTKB3.AA HYR 745-756 50 3.814148 2.5 Pfam 64-75 (86) Show / Hide 
Range on Protein: 745-756
Range on HMM: 64-75/86
Sequence Identity: 50% (6 aa)

TVDYMATDRSGN
|| | ..|..||
TVTYTFQDNAGN
HYR RTKB3.AA HYR 829-852 36 1.779882 3.59 Pfam 62-86 (86) Show / Hide 
Range on Protein: 829-852
Range on HMM: 62-86/86
Sequence Identity: 36% (9 aa)

DYSIVYTARDDVGNTA-HATRNLTV
.... ||..|  ||.|   | . ||
QTTVTYTFQDNAGNQADTCTFTVTV
HYR RTKB3.AA HYR 1026-1046 36 7.620799 1.51 Pfam 58-79 (86) Show / Hide 
Range on Protein: 1026-1046
Range on HMM: 58-79/86
Sequence Identity: 36% (8 aa)

PAGSTYTVDFIVTDAAGNSD-S
| | ..||  ...|.|||.. .
PVGEQTTVTYTFQDNAGNQADT
HYR RTKB3.AA HYR 1154-1181 41 6.398754 1.76 Pfam 58-86 (86) Show / Hide 
Range on Protein: 1154-1181
Range on HMM: 58-86/86
Sequence Identity: 41% (12 aa)

PVGTLYVVNASVMDGAGNTA-TRTFRYLI
|||  ..| . . | |||.| | ||.  .
PVGEQTTVTYTFQDNAGNQADTCTFTVTV
HYR RTKB3.AA HYR 1182-1188 85 10.733995 1.02 Pfam 1-7 (86) Show / Hide 
Range on Protein: 1182-1188
Range on HMM: 1-7/86
Sequence Identity: 85% (6 aa)

VDTTPPV
||||||.
VDTTPPT
HYR RTKB3.AA HYR 1237-1261 37 3.556569 2.6 Pfam 60-86 (86) Show / Hide 
Range on Protein: 1237-1261
Range on HMM: 60-86/86
Sequence Identity: 37% (10 aa)

G-TYLVQYRTNDRYGNPA-EAARTVIV
| .. |.|   |. ||.| .   || |
GEQTTVTYTFQDNAGNQADTCTFTVTV
Kinase RTKB3.AA RTKB 1460-1722 70 4.1e-204 684.38 In-house 1-264 (264) Show / Hide 
Range on Protein: 1460-1722
Range on HMM: 1-264/264
Sequence Identity: 70% (185 aa)

VRLGEKLGNGAFGQVFRAWFCNRHSGEERSCAAKALKPGAPFRARQDFLSEMTVMKEIGAHPNIIGIFGHCLRDEPHILLVELAELGNLRDYLRKCRTSQ
|.|||||||||||.||.||..|||...|.|||||.|||||....||||.||||||||.|.|||.|||.||||.|||.||||||.||||||||||.||.||
VWLGEKLGNGAFGEVFQAWVRNRHMNTEQSCAAKVLKPGASYEERQDFCSEMTVMKELGWHPNVIGIIGHCLQDEPYILLVELCELGNLRDYLRMCRASQ

SKPQLLGSRQLADFCLQIASGMSFLERKNVIHRDLAARNVLLSQSLACKICDFGLARSIENEDYETTATKLPVKWMAPESLGYRIYTSKS-DVWSFGVTM
..|| | ..||.|||.|||.||.||...|||||||.|||||..|.|.|||||||.||.|..|.||||.|.||.|||||||...||||.|| |||||||||
HNPQSLKQAQLVDFCHQIACGMAFLHQHNVIHRDLCARNVLVDQQLHCKICDFGMAREIDHECYETTCTRLPIKWMAPESWAHRIYTTKSGDVWSFGVTM

WEIFSLGGTPYVKHRNVDILSLLADGYRLPKPRQAPGQADAIARMCWMHEADNRPTFLELVDLL
|||||||||||...||.||...|..|.|||||||.| .||.|..|||..||..||.| ||||..
WEIFSLGGTPYQQYRNGDIFYWLESGHRLPKPRQMPQAADHIMQMCWQMEAQHRPDFDELVDAF
Kinase RTKB3.AA TyrKc 1460-1722 37 6e-120 405.71 SMART 1-280 (280) Show / Hide 
Range on Protein: 1460-1722
Range on HMM: 1-280/280
Sequence Identity: 37% (112 aa)

VRLGEKLGNGAFGQVFRAWFCNRHSGEERSCAAKALKPGAPFRARQDFLSEMTVMKEIG-AHPNIIGIFGHCLRD-------EPHILLVELAELGNLRDY
..||.|||.||||.|...          . .| | ||..|    |.||..|. .|...|  ||||. ..| |. .       ||. ...|....|.|.||
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

LRKCRTSQSKPQLLGSRQLADFCLQIASGMSFLERKNVIHRDLAARNVLLSQSLACKICDFGLARSIENE-------DYETT----ATK--LPVKWMAPE
|||.|        |  ..| .||.|||.||..|..||.|||||||||.|..  . .||.||||.| |...       || ..     .|  ||..|||||
LRKHRPK------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPE

SLGYRIYTSKSDVWSFGVTMWEIFSLGGTPYVK-----HRNVDILSLLADGYRLPKPRQ--------APGQADAIARMCWMHEADNRPTFLELVDLL
.. |...|.|||||||||.|||||..|..||         | ... .. .|||.|.|          .|     | ..||......|||| |.....
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RTKB3.AA Pkinase_Tyr 1460-1722 43 4.4e-119 403.93 Pfam 1-270 (270) Show / Hide 
Range on Protein: 1460-1722
Range on HMM: 1-270/270
Sequence Identity: 43% (119 aa)

VRLGEKLGNGAFGQVFRAWFCNRHSGEERSCAAKALKPGAPFRA--RQDFLSEMTVMKEIGAHPNIIGIFGHCL-RDEP--HILLVELAELGNLRDYLRK
...|.||| ||||.|...     .....  .| | ||.||  ..  |.||..|. .||..| ||||.   | |. ..||  ... .|....|.|.|||||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

CRTSQSKPQLLGSRQLADFCLQIASGMSFLERKNVIHRDLAARNVLLSQSLACKICDFGLARSIENEDYE---TTATKLPVKWMAPESLGYRIYTSKSDV
 |   . .| |   .| ..|.|||.||..||.|| |||||||||.|.. .. .||||||||| |.|.||    .. .|||.||||||.. |...|.||||
HR---EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV

WSFGVTMWEIFSLGGTP-YVKHRNVDILSLL-ADGYRLPKPRQAPGQADAIARMCWMHEADNRPTFLELVDLL
|||||.|||||..|..| |    | ... ..  ||||.|.|. .|     . ..||......|||| |..  |
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase RTKB3.AA TK 1460-1722 23 3.4e-116 391.23 In-house 1-486 (486) Show / Hide 
Range on Protein: 1460-1722
Range on HMM: 1-486/486
Sequence Identity: 23% (115 aa)

VRLGEKLGNGAFG---QVFRAWFCNR---------------------HSGEERSCAAKALKPGAPFRARQDFL----------------SEMTVMKE-IG
..||.||| |.||   .|....  .|                     ..|..  .| | ||.|..  ... |.                .|| .|.. .|
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

AHPNIIGIFGHCLRD------------EPHILLVELAELGN----LRDYLRKCRTSQSKPQL--------------------------------------
 ||||. ..|.|...            || ....|....|.    |||||||||   ...|                                       
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LGSRQLADFCLQIASGMSFLERK------NVIHRDLAARNVLLSQSLA-----------CKICDFG---
                               |  .||  .|.|||.||..|..|      |..||||||||.|.....            |||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LARSIENEDYETTAT--------------------------KLPVKWMAPESLG---------YRIYTSKSDVWSFGVTMWEIFSLG-GTPYVKH
     ||| |...|. ....                          |||..|||||.|          |...|.|||||||||.|||||..| ...|  .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

RN---------VDILSLLADG--------------YRLPKPRQAP--------------GQADAIARMCWMHEADNRPTFLELVDLL
 |          ... .| .|              .|.|.| ..|                 . . ..|| .... |||| .|.. |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase RTKB3.AA TK-Unique 1460-1722 39 2.4e-102 346.32 In-house 1-294 (294) Show / Hide 
Range on Protein: 1460-1722
Range on HMM: 1-294/294
Sequence Identity: 39% (115 aa)

VRLGEKLGNGAFGQVFRAWFCN--RHSGEERSCAAKALKPGAPFRARQDFLSEMTVMKEIGAHPNIIGIFGHCLRD-EPHILLVELAELGNLRDYLRKCR
...|...| ||||||.|. ...   |... .. | |.|| .| .  .||||.|  .|||.|.||||. ..| | .. ||. .. | .. |||..|||.||
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

TS-----------------QSKPQL--LGSRQLADFCLQIASGMSFLER--KNVIHRDLAARNVLLSQSLACKICDFGLARSIEN-EDYETTAT--KLPV
                    .||..  . ...|. |. |||.||..|..  |...||||.||||||.  . |||||||.|| ... ..|... .  ..|.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

KWMAPESLG--YRIY-TSKSDVWSFGVTMWEIFSLGGTPYVKHRNVDILSLLADGYRLPKPRQA-PGQADAIARMCWMHEADNRPTFLELVDLL
.|||||||   ...| |.|||||||||.|||||.||..|| . .. ||. .. ||||.|.| .  . .   . . || .|.. ||.| .... |
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase RTKB3.AA UTK 1460-1722 33 7.3e-95 321.46 In-house 1-296 (296) Show / Hide 
Range on Protein: 1460-1722
Range on HMM: 1-296/296
Sequence Identity: 33% (98 aa)

VRLGEKLGNGAFGQVFRAWFCN-RHSGEERSCAAKALKPGAPFRARQD----FLSEMT---VMKEIGAHPNIIGIFGHCLRDEPHILLVELAELGNLRDY
|.||..|| ||||.|..| | . .  ..|  .| |.....|. .  ..    |. | .   .||    |||...  | |...|| ....|..| |.||.|
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LRKCRTSQS-KPQLLGSRQLADFCLQIASGMSFLERKNVIHRDLAARNVLLSQS-------LACKICDFG---LARSIE---------NEDYETT--ATK
||..| ..   | .| ..|. .....||.||..|......||||||||.|. ..       . |||.|||   ..| .          . .|..   ...
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LPVKWMAPESLGYR-IYTSKSDVWSFGVTMWEIFSLGGTPYVKHRNVDILSLLADG--YRLPKPRQAPGQADAIARMCWMHEADNRPTFLELVDLL
.|..|||||.| ..  .|.|||||||||..|||.. | .||  . |....  . .|  ||.|.|.. | .   . . ||. . ..||.| .||. .
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase RTKB3.AA FGFR 1460-1722 38 6.6e-87 295.02 In-house 1-293 (293) Show / Hide 
Range on Protein: 1460-1722
Range on HMM: 1-293/293
Sequence Identity: 38% (113 aa)

VRLGEKLGNGAFGQVFRAWFC---NRHSGEERSCAAKALKPGAPFRARQDFLSEMTVMKEIGAHPNIIGIFGHCLRDEPHILLVELAELGNLRDYLRKCR
  ||. || |.|||| .|      . .  .|   | | || ..  .   |  ||| .|| || |.|||   | |  . |   .||... |||||.||. |
LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVKMLKMNHTDKDLSDLVSEMEMMKMIGKHKNIINLLGCCTQEGPLYVIVEYCHHGNLRDFLRARR

-----TSQSKP-----------QL--------LGSRQLADFCLQIASGMSFLERKNVIHRDLAARNVLLSQSLACKICDFGLARSIENEDY--ETTATKL
      ... .           |         |....|  .  |.| || .|. . .||||||||||| .     ||||||||| | . ||   ||   |
PPGMDYKKDSQEYTDYKPRKPEQQDDIELIPNLTQKDLVSCAYQVARGMEYLASRKCIHRDLAARNVLVTDDYVMKICDFGLARDIHCIDYYRKTTNGRL

PVKWMAPESLGYRIYTSKSDVWSFGVTMWEIFSLGGTPYVKHR-NVDILSLLADGYRLPKPRQAPGQADAIARMCWMHEADNRPTFLELVDLL
|.||||||.|  |.||..|||||.|| .|||. .||.||       .. ..|  |.|. || . .     . . ||  ... |||| .||. |
PIKWMAPEALFDRVYTHQSDVWSYGVLLWEIMTYGGQPYPHIPSVEELYKYLKEGHRMEKPHNCSQEIYHMMCQCWHFKPCQRPTFKQLVEYL
Kinase RTKB3.AA Src 1460-1722 37 9.7e-87 294.48 In-house 1-255 (255) Show / Hide 
Range on Protein: 1460-1722
Range on HMM: 1-255/255
Sequence Identity: 37% (101 aa)

VRLGEKLGNGAFGQVFRAWFCNRHSGEERSCAAKALKPGAPFRARQDFLSEMTVMKEIGAHPNIIGIFGHCLRDEPHILLVELAELGNLRDYLRKCRTSQ
..| .|||.| || |. . . ..        | | ||||    . ..|| |  .||.   |.... ..  | ..||     |. . |.| |||.|    .
IKLCRKLGQGQFGEVWMGYWNGNT-----KVAVKTLKPGT--MSPEAFLQEAQIMKKL-RHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK----D

SKPQLLGSRQLADFCLQIASGMSFLERKNVIHRDLAARNVLLSQSLACKICDFGLARSIE--NEDY-ETTATKLPVKWMAPESLGYRIYTSKSDVWSFGV
.. . |  .|| |.  |.|.||..||..|.||||||||||| .....||..|||||| |.   . |   .  |.|.||.||| . |. .| ||||||||.
GEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGI

TMWEIFSLGGTPYVKHRNVDILSLLADGYRLPKPRQAPGQADA-IARMCWMHEADNRPTFLELVDLL
 ..||.. | .||   .| . |  .  |||.|.|.. | .    | ..||  ... ||||  | . |
LLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase RTKB3.AA Fer 1460-1723 32 1.8e-80 273.64 In-house 1-283 (283) Show / Hide 
Range on Protein: 1460-1723
Range on HMM: 1-283/283
Sequence Identity: 32% (93 aa)

VRLGEKLGNGAFGQVFRA----WFCNRHSGEERSCAAKALKP-GA-PFRA-RQDFLSEMTVMKEIGAHPNIIGIFGHCLRDEPHILLVELAELGNLRDYL
| ||.|||.|||| |...     ...  . . ...| |  |  .. . .. ...|. |. .|.    |||.. ..| |  ..|  .. |..  |.|..||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

RKCRTSQSKPQ-LLGSRQLADFCLQIASGMSFLERKNVIHRDLAARNVLLSQ-SLACK--ICDFGLARS--IENEDYETT--ATKLPVKWMAPESLGYRI
.|      ... ..  ... ..|.|.|.|| .|. ||.||||.||||.|...  . .|  | |||..|    . .||.    |.|.|..|.|||.. ..|
KK------NKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGI

YTSKSDVWSFGVTMWEIFSLGGTPYVK------HRNVD---ILSLLADGYRLPKPRQAPGQADAIAR-MCWMHEADNRPTFLELVDLLT
|..|.|||||||..||||. | .||          ||.   .     .||..| | ..|     |   .|| .. ..|||. |..  | 
YSPKTDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase RTKB3.AA Ack 1460-1722 39 1.1e-75 254.78 In-house 1-266 (266) Show / Hide 
Range on Protein: 1460-1722
Range on HMM: 1-266/266
Sequence Identity: 39% (108 aa)

VRLGEKLGNGAFGQVFRAWFCNRHSGEERSCAAKALKPG---APFRARQDFLSEMTVMKEIGAHPNIIGIFGHCLRDEPH-ILLVELAELGNLRDYLRKC
..|.||||.| || | |.   |  .|.  . | | |...   .|  . .||| |  .|  .  ||...  .|   .| |   .  |||..| | | ||| 
ITLCEKLGDGCFGVVWRGEWTN-PGGKHIQVAVKCLRSDKMQQP-NCMDDFLREVAIMHSL-DHPHLVRLYG-VVLDQPMLMMVTELAPCGSLLDCLRK-

RTSQSKPQLLGSRQLADFCLQIASGMSFLERKNVIHRDLAARNVLLSQS-LACKICDFGLARSI-ENED-YETTATK---LPVKWMAPESLGYRIYTSKS
  . ... .     | |||.|||.||..|| |. |||||||||.||       ||||||| |.  .||| | .  ..   .|  |.|||.| .|  ...|
HCRTAFFLI---HTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHAS

DVWSFGVTMWEIFSLGGTPYVKHRNVDILSLLA-DGYRLPKPRQAPGQADAIARMCWMHEADNRPTFLELVDLL
|||.||||.|| || |  |..  .  .|| ..  .| |||.|   |    ...  || |..  |||| ...|.|
DVWMFGVTLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL
Kinase RTKB3.AA Eph 1460-1722 36 3.1e-73 245.32 In-house 1-264 (264) Show / Hide 
Range on Protein: 1460-1722
Range on HMM: 1-264/264
Sequence Identity: 36% (99 aa)

VRLGEKLGNGAFGQVFRAWFCNRHSGEER---SCAAKALKPGAPFRARQDFLSEMTVMKEIGAHPNIIGIFGHCLRDEPHILLVELAELGNLRDYLRKCR
... . .| | || | .     .   .|      | |.|| |.. ..| ||||| ..|     |||||   |   . .|   ..|  |.| | ..||.  
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQF-DHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQHD

TSQSKPQLLGSRQLADFCLQIASGMSFLERKNVIHRDLAARNVLLSQSLACKICDFGLARSIENED-----YETTATKLPVKWMAPESLGYRIYTSKSDV
        . . ||      ||||| .|   | .||||||||.|... | ||. |||| | .|...     |.|.  | |..| ||| . ||..|| |||
G------QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTRGGKIPIRWTAPEAIAYRKFTSASDV

WSFGVTMWEIFSLGGTPYVKHRNVDILSLLADGYRLPKPRQAPGQADAIARMCWMHEADNRPTFLELVDLL
||.|. |||. | |  ||    | |...   .||||| |.  | .   ..  ||  .  .||.| ..|  |
WSYGIVMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase RTKB3.AA VEGFR 1563-1722 46 9e-61 208.22 In-house 168-332 (332) Show / Hide 
Range on Protein: 1563-1722
Range on HMM: 168-332/332
Sequence Identity: 46% (76 aa)

QLLGSRQLADFCLQIASGMSFLERKNVIHRDLAARNVLLSQSLACKICDFGLARS-I-ENEDYETTAT--KLPVKWMAPESLGYRIYTSKSDVWSFGVTM
. | .  |  . .|.| || ||. ...|||||||||.||. .   |||||||||. |  . || .     .|| |||||||.  ..||..|||||.|| .
DPLTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLCENNVVKICDFGLARHGIYKDPDYVRKGDQGRLPIKWMAPESIFDKVYTTYSDVWSYGVFL

WEIFSLGGTPYVKHR-NVDILSLLADGYRLPKPRQAPGQADAIARMCWMHEADNRPTFLELVDLL
|||||||| ||     . .  . | ||||. .|  .. .   |   ||  |   ||.| |||  |
WEIFSLGGSPYPGVQIDEEFCNRLKDGYRMRAPDYCTPEIYHIMLDCWHKEPEERPHFSELVEHL
Kinase RTKB3.AA S_TKc 1460-1726 23 7.1e-45 156.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 1460-1726
Range on HMM: 1-231/231
Sequence Identity: 23% (64 aa)

VRLGEKLGNGAFGQVFRAWFCNRHSGEERSCAAKALKPGAPFRARQDFLSEMTVMKEIGAHPNIIGIFGHCLRDEPHILLVELAEL--GNLRDYLRKCRT
 ....|.| ||||.|....  .      | .| | .|        .....|. ..|.   ||||. .....   .   .  |...   |.|.||..|...
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

SQSKPQLLGSRQLADFCLQIASGMSFLERKNVIHRDLAARNVLLSQSLACKICDFGLARSIENEDYETTATKLPVKWMAPESLGYRIYTS-KSDVWSFGV
 . ... .   . . .. ||.... .. ....|||||   |.||..    ||||||||| .       |       .|||| |    |.  |.|.||.|.
-HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

TMWEIFSLGGTPYVKHRNVDILSLLADGYRLPKPRQAPGQADAIARMCWMHEADNRPTFLELVD-----LLTAFI
...| .. | .|.       .. ..            . .|  . | |.  . ..|||  |.        .  ..
ILYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RTKB3.AA Pkinase 1460-1669 26 6.8e-30 106.78 Pfam 1-212 (293) Show / Hide 
Range on Protein: 1460-1669
Range on HMM: 1-212/293
Sequence Identity: 26% (61 aa)

VRLGEKLGNGAFGQVFRAWFCNRHSGEERSCAAKALKPGAPFR--ARQDFL-SEMTVMKEIGAHPNIIGIFGHCLRDEPHILLV-ELAELG----NLRDY
 ..|.|.| |.||.|...    .| |...  | | .|         ..... ||  .||..  ||||. ... . . ..|| .| |..| |     | ||
YHIGRKIGSGSFGCVYKC----HHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDY

LRKCRTSQSKPQLL--GSRQLADFCLQIASGMSFLERKNVIHRDLAARNVLLSQSLAC----KICDFGLARSI-ENEDYETTATKLPVKWMAPESLG-YR
..      ..   .    ... ....||..|. .. ....|||||   |.|...   .    ||||||||. . .  .  .|       .|||| .  ..
IST-----WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQ

IYTSKSDVWSFGVTMWEIFSLGGTPY
 |..|.|.||.|....| .. | .|.
YYGPKVDMWSCGCILYEMLC-GRPPF
Kinase RTKB3.AA VEGFR 1460-1556 35 7.8e-11 37.29 In-house 1-101 (332) Show / Hide 
Range on Protein: 1460-1556
Range on HMM: 1-101/332
Sequence Identity: 35% (36 aa)

VRLGEKLGNGAFGQVFRAWFCN-RHSGEERSCAAKALKPGAPFRARQDFLSEMTVMKEIGAHPNIIGIFGHCLR---DEPHILLVELAELGNLRDYLRKC
 .||  || ||||||  |   . | .   .  | | ||.||        .||. ... || | |     | |       |    ||    ||| .|||  
LKLGKMLGRGAFGQVHEASAFGIRKMETCTTVAVKMLKEGATASEHRALMSELKMLIHIGHHLNVVNFLGCCTKNIQKGPLMVIVEYCCFGNLSNYLRTK

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