RTKF2

Species: M.brevicollis
Alias: RTKF2
External Links:
Annotation:

Classification

Group: TK
Family: RTKF

Sequence

Name Sequence Type Origin Length Description Download
RTKF2.AA Protein None 936 None Fasta, JSON
RTKF2.kin_dom Protein Kinase Domain None 266 None Fasta, JSON

Protein domain

Protein domains of RTKF2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LDLa RTKF2.AA LDLa 351-391 30 2e-06 28.74 SMART 1-47 (47) Show / Hide
Range on Protein: 351-391
Range on HMM: 1-47/47
Sequence Identity: 30% (15 aa)

HCPYV--PPFSCPTAGDRTILATQICDGVPDCINGADE------AECFA
.||      | |.    | |  .. |||..|| .| ||      . |  
TCPPDHPNQFQCG--NGRCIPKSWVCDGDNDCGDGSDEWPFFDPENCPQ

Ldl_recept_a RTKF2.AA Ldl_recept_a 374-389 55 1.1e-05 20.11 Pfam 24-41 (41) Show / Hide
Range on Protein: 374-389
Range on HMM: 24-41/41
Sequence Identity: 55% (10 aa)

CDGVPDCINGADE--AEC
||| ||| .| ||  . |
CDGDPDCHDGSDEWPENC

Kinase RTKF2.AA RTKF 661-926 68 3.5e-233 758.96 In-house 1-272 (272) Show / Hide
Range on Protein: 661-926
Range on HMM: 1-272/272
Sequence Identity: 68% (186 aa)

VQLGEELGSGNFGRVLHGLWSQDKGSAIPVAIKFITTADGMDWRSQLLKEAVAMNTIGQHPHVIQLHGLLMTPFEDETVAFVMEFAAHGDLRSYLQREDV
..|||.||.|.||||.||.|.|.||...|||||.|.|.|.|.||.|.|.|..|||..|||||.||..|.||||||....|||||||.|||.|.|||..||
IMLGEQLGHGHFGRVHHGYWRQQKGQRQPVAIKHIHTQDMMNWRRQMLRECCAMNRVGQHPHIIQFFGILMTPFEQNEMAFVMEFAPHGDMRRYLQQHDV

EFGVAHTLQAAHQVVALALGFISKQGLVHRDVAARNVLVFEDQPTMLVKLTDFGLARVLSQHQEYYRSAQDDSLPFRWMAPEAITQRRFSEKSDVWSFGV
..|.||.|.|||||||.|..|||.||||||||||||||||||||.|.||||||||||||||||.||||.|...|||||||||||..|||..||||||||.
DLGRAHMLDAAHQVVAEAMVFISRQGLVHRDVAARNVLVFEDQPRMYVKLTDFGLARVLSQHQDYYRSMQNEELPFRWMAPEAIMHRRFTQKSDVWSFGM

LLFELTTRGRAPYGNQSNPVVLQNIARGKTLQLPPSAP------VSLHWLCAEIWVFEPEQRPSFEQIVEHL
.||||.|||..||||...|||||.|.||||||.|.|.|      ||.||||..||.|.|||||.|..|..||
MLFELFTRGDVPYGNMPHPVVLQFIRRGKTLQMPDSCPPDVCRFVSIHWLCQRIWTFDPEQRPDFDIIEDHL

Kinase RTKF2.AA TK 661-926 20 5.1e-94 315.56 In-house 1-486 (486) Show / Hide
Range on Protein: 661-926
Range on HMM: 1-486/486
Sequence Identity: 20% (102 aa)

VQLGEELGSGNFG---RVLHGLWSQDK----------------------GSAIPVAIKFIT--TADGMDWRSQ--------------LLKEAVAMNT-IG
..||..||.|.||   .|  |.| ...                      |  .|||.| ..  .|. .. . .              .. |.  |.  .|
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHPHVIQLHGLLMTPFED---------ETVAFVMEFAAHGD----LRSYLQREDVEFGV-----------------------------------------
.||....|.|  . . .          | .  |||...|||    ||.||.. . .|                                           
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------AHTLQAAHQVV----------------------ALALGFISKQ------GLVHRDVAARNVLVFEDQP--------TMLVKLTDFG----
          . |..  .|..                      | .. .....      ..||||.||||.||.|. .        .. .|..|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LARVLSQH-----------------------QEYYRSAQDDSLPFRWMAPEAIT---------QRRFSEKSDVWSFGVLLFELTTRGRAPYGN-QS
    ||| . ..                       |.|||..... ||.||||||...          ..|..||||||||||..|. |.|..||.   |
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N---------PVVLQNIARGKT------------LQLP--PSAP--------------VSLHWLCAEIWVFEPEQRPSFEQIVEHL
|           |.... || .            ...|  | .|                .. |. . | ..||.||.|.|..| |
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase RTKF2.AA TyrKc 661-926 32 1.7e-92 314.48 SMART 1-280 (280) Show / Hide
Range on Protein: 661-926
Range on HMM: 1-280/280
Sequence Identity: 32% (95 aa)

VQLGEELGSGNFGRVLHGLWSQDKGSAIPVAIKFITTADGMDWRSQLLKEAVAMNTIG-QHPHVIQLHGLLMTP----FEDETVAFVMEFAAHGDLRSYL
..||..||.|.||.| .| |.      |.||.| .        |  ...||  |  .| .||....|.|  ...     ..| .  |||...||||..||
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

QREDVEFGVAHTLQAAHQVVALALGFISKQGLVHRDVAARNVLVFEDQPTMLVKLTDFGLARVLSQH------QEYYRSA---QDDS-LPFRWMAPEAIT
..   .. ... |. ..| .|    ........||| ||||.|| |..    || .||||.| .  .      ..|||..   . .. || ||||||.| 
RKHRPKLCMKDLLSFCWQ-IACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

QRRFSEKSDVWSFGVLLFELTTRGRAPYGN-----QSNPVVLQNIARGKTLQLPPS--------APVSLHWLCAEIWVFEPEQRPSFEQIVEHL
 ..|..|||||||||...|. |.|  || .      ||  |.... .|. .  ||.        .|  .. .  . | ..||.||.|..|.| .
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase RTKF2.AA Pkinase_Tyr 661-926 35 4.7e-88 298.83 Pfam 1-270 (270) Show / Hide
Range on Protein: 661-926
Range on HMM: 1-270/270
Sequence Identity: 35% (100 aa)

VQLGEELGSGNFGRVLHGLWS-QDKGSAIPVAIKFITTADGMDW---RSQLLKEAVAMNTIGQHPHVIQLHGLLMTPFEDET--VAFVMEFAAHGDLRSY
...|..||.|.||.| .| |  ....  ||||.| .   . |.    |  ...||  | ..|.||....|.|  .   ..|   .  |||...||||..|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT--DQGEPNQIYIVMEYMPHGDLLDY

LQRE---DVEFGVAHTLQAAHQVVALALGFISKQGLVHRDVAARNVLVFEDQPTMLVKLTDFGLARVLSQHQEYY-RSAQDDSLPFRWMAPEAITQRRFS
|..    .  . . . || ..| .| .. . . ....|||.||||.|| |   .. || .|||||| . .. .|| |....  || .|||||.|  ..|.
LRKHREDKQPLTMKDLLQMCWQ-IAKGMEYLESKNCIHRDLAARNCLVTE---NNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFT

EKSDVWSFGVLLFELTTRGRAP-YGNQSNPVVLQNI-ARGKTLQLPPSAPVSLHWLCAEIWVFEPEQRPSFEQIVEHL
.||||||||||..|. |.|. | | . ||  |.. |  .|  .  |. .|  .. |  . | ..||.||.|..|.|.|
TKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase RTKF2.AA RTKA 661-908 30 9e-79 268.0 In-house 1-314 (314) Show / Hide
Range on Protein: 661-908
Range on HMM: 1-314/314
Sequence Identity: 30% (96 aa)

VQLGEELGSGNFGRVLHG-LWSQD----KGSAIPVAIKFIT--TADGMDWRSQLLKEAVAMNTIGQHPHVIQLHGLLMTPFE---DETVAFVMEFAAHGD
.|  . .|.|.|..|.   | .      .|.  .||||       .. .  |  ..|.     .. .||.| ||| .... .     ... |.|.. || 
MQVRHVVGHGHFSQVYQASLQDMEDEMRQGPQ-CVAIKECDDLMLNDKTTLSAWMREIMLLHSMRDCPHIIGLHGVCLPREDKHHQSHCGMVCEWCPHGN

LRSYLQRED----------------------VEFGVAHTLQAAHQVV------ALALGFISKQGLVHRDVAARNVLVFEDQPTMLVKLTDFGLARVLSQH
||  ...                            .|   ||..|..      | |. . .| | ||||||||||||.  ||. ..|| |||| ||... 
LRDFVRQHPHFSAPVVATIAMQHSGEPNASPKLLSEAQCHQALLQMCPCWAQVAQAMAYLAKCGIVHRDVAARNVLVMSLQPAFHCKLADFGLSRVMPS-

QEYYRSAQDDSLPFRWMAPEAITQRRFSEKSDVWSFGVLLFELTTRGRAPYG------------------------------NQSNPVVLQNIARGKTLQ
 .||.| .|| .||||||||.| .||.||.|||||||||. || |.| .|..                              . . .   |   .|.||.
SDYYKSRADDEMPFRWMAPECIMERRYSEHSDVWSFGVLVWELLTHGQTPWQNCESHQIVALLMRGERLTFAPTINAALRDSGCDLHHIIQMLKQGQTLP

LPPSAPVSLHWLCAEI
.||..|  |   |.. 
MPPCCPPCLQRFCFWC

Kinase RTKF2.AA UTK 661-926 31 4.9e-74 252.27 In-house 1-296 (296) Show / Hide
Range on Protein: 661-926
Range on HMM: 1-296/296
Sequence Identity: 31% (96 aa)

VQLGEELGSGNFGRVLHGLWSQDK------GSAIPVAIKFITTADGMDWRS---QLLKEAV---AMNTIGQHPHVIQLHGLLMTPFEDETVAFVMEFAAH
||||..||.|.|| | .. . |..      . |..|.    ..||. . .    ....||     |     ||.|..| |. .        . |.|... 
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ---HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP---WMIVTEYMEN

GDLRSYLQREDVEFG-------VAHTLQAAHQVVALALGFISKQGLVHRDVAARNVLVFEDQ----PTMLVKLTDFG---LARVLS--------QHQEYY
|||||||.|   ...         . |. | . .| .. ... .|.||||.||||.||...       |..|. |||   ..| ..        . ..||
GDLRSYLRRHRPTPPACPHWLTLHQRLCMAWD-IARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYY

RSAQDDSLPFRWMAPEAITQR-RFSEKSDVWSFGVLLFELTTRGRAPYGNQSNPVVLQNIARGKTLQLPP--SAPVSLHWLCAEIWVFEPEQRPSFEQIV
.....|..|.|||||||.|.. ||..|||||||||...|. |.||.||.. ||. |.... .|  ...|.  . | ..  |  . |  .|. ||.||..|
MAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLV

EHL
. .
QQM

Kinase RTKF2.AA RTKL 661-926 36 1.9e-72 190.74 In-house 1-259 (259) Show / Hide
Range on Protein: 661-926
Range on HMM: 1-259/259
Sequence Identity: 36% (99 aa)

VQLGEELGSGNFGRVLHGLWSQDKGSAIP--VAIKFITTADGMDWRSQLLKEAVAMNTIGQHPHVIQLHGLLMTPFEDETVAFVMEFAAHGDLRSYLQRE
. |..|||.|.|.||  .     .. ..|  |||| .   .        |.||| . .   |||.||.||  . |   .  | ..| |. | || ||  .
FILENELGRGQFSRVYQA---RSCSRMVPTQVAIKIAHEQQSKNQMDAVLYEAVLLHQL-HHPHIIQMHGCTAVP---QRMAMILELAPNGNLREYLRHD

DVE---FGVAHTLQAAHQVVALALGFISKQGLVHRDVAARNVLVFEDQPTMLVKLTDFGLARVLSQHQEYYRSAQDDSLPFRWMAPEAITQRRFSEKSDV
|      . .  ||   | || || .|    ..||| |.||||     | |. || |||| | |   |.|||  |.| .||||| ||          |||
DAPSSSWPQRQRLQWLCQ-VAQALAYIHQRRMIHRDLASRNVLLV---PMMVCKLSDFGLSRRLQNEQDYYRPQQNDHVPFRWMSPETLNGKPHTMASDV

WSFGVLLFELTTRGRAPYGNQSNPVVLQNIARGKTLQLPPSAPVSLHWLCAEIWVFEPEQRPSFEQIVEHL
| |||. .|  | |  ||     | |   .     | ||   |  |  | |  |   |. ||    .   |
WAFGVVCYEVIT-GQVPYADTDMPQVVALLKNEGRLALPAGTPPGLERLVAACWQTSPDVRPTAAALSPAL

Kinase RTKF2.AA Src 661-926 35 1.5e-67 228.51 In-house 1-255 (255) Show / Hide
Range on Protein: 661-926
Range on HMM: 1-255/255
Sequence Identity: 35% (95 aa)

VQLGEELGSGNFGRVLHGLWSQDKGSAIPVAIKFITTADGMDWRSQLLKEAVAMNTIGQHPHVIQLHGLLMTPFEDETVAFVMEFAAHGDLRSYLQ--RE
..| ..||.|.|| |  |.| .     ..||.| .  .. |.   ..|.|| .| .  .|....||.       ..| .  | |. .|| |  ||.  .|
IKLCRKLGQGQFGEVWMGYWNG----NTKVAVKTLKPGT-MS-PEAFLQEAQIMKKL-RHEKLVQLYAVCS---QEEPIYIVTEYMSHGSLLDYLKKDGE

DVEFGVAHTLQAAHQVVALALGFISKQGLVHRDVAARNVLVFEDQPTMLVKLTDFGLARVLSQHQEYYRSAQDDSLPFRWMAPEAITQRRFSEKSDVWSF
  .  . . .  | | ||    ..... ..||| ||||||| |.    ..|  ||||||.. .  . | . ..  .| .|.|||||. .||. |||||||
GRHLHLPQLIDMAAQ-VAEGMAYLESMNYIHRDLAARNVLVGENN---VCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSF

GVLLFELTTRGRAPYGNQSNPVVLQNIARGKTLQLPPSAPVSLHW-LCAEIWVFEPEQRPSFEQIVEHL
|.|| |. |.|| ||   .|. |||.. ||  .  |.  | .|.  .  . |  .||||| || . . |
GILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL

Kinase RTKF2.AA Ack 661-926 33 3.7e-60 201.63 In-house 1-266 (266) Show / Hide
Range on Protein: 661-926
Range on HMM: 1-266/266
Sequence Identity: 33% (91 aa)

VQLGEELGSGNFGRVLHGLWSQDKGSAIPVAIKFITTADGMDW--RSQLLKEAVAMNTIGQHPHVIQLHGLLM-TPFEDETVAFVMEFAAHGDLRSYLQR
. |.|.||.| || |  |.|..  |  |.||.|      .      . .|.|. .|  . .|||.. |.|.   .|     .  |.|.|  | |   |  
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQVAVKCLRSDKMQQPNCMDDFLREVAIMHSL-DHPHLVRLYGVVLDQPM----LMMVTELAPCGSLLDCLRK

EDVE--FGVAHTLQAAHQVVALALGFISKQGLVHRDVAARNVLVFEDQPTMLVKLTDFGLARVLSQHQEYYRSAQDD--SLPFRWMAPEAITQRRFSEKS
 .    |   ||| .    .| .. .   ....|||.||||.|.| |    .||  |||| | | |   |||..      .|| |.|||....|.|| .|
-HCRTAFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDD--RKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHAS

DVWSFGVLLFELTTRGRAPYGNQSNPVVLQNIA-RGKTLQLPPSAPVSLHWLCAEIWVFEPEQRPSFEQIVEHL
|||.||| | |  . |. |.   .   .||.|   |  |  |.  |  .  .  . | ..|. ||.| .|.. |
DVWMFGVTLWEMFSYGEEPWAGCNGYQILQKIDKEGERLPRPDCCPEDIYQMMMQCWQHHPADRPTFSAIRDQL

Kinase RTKF2.AA Frk 661-930 37 2.6e-55 190.09 In-house 1-260 (260) Show / Hide
Range on Protein: 661-930
Range on HMM: 1-260/260
Sequence Identity: 37% (103 aa)

VQLGEELGSGNFGRVLHGLWSQDKGSAIPVAIKFITTADGMDWRSQLLKEAVAMNTIGQHPHVIQLHGLLMTPFEDETVAFVMEFAAHGDLRSYLQ---R
.||  .|||| || |  ||| .    ..|||.| .  .  || .  .|.||  |  . .|| .|||. .      .| .  . |   || |  |||   .
IQLIRRLGSGQFGEVWEGLWNN----TTPVAVKTL-KPGTMDPN-DFLREAQIMKKL-RHPKLIQLYAVCTV---EEPIYIITELMRHGSLQEYLQAIND

EDVEFGVAHTLQAAHQVVALALGFISKQGLVHRDVAARNVLVFEDQPTMLVKLTDFGLARVLSQHQE-YYRSAQDDSLPFRWMAPEAITQRRFSEKSDVW
.  .  .   .. | || |  . .. .|  .|||.||||||| |.     .|. |||||||| . .|  | | ..  .| .| ||||.   .|. |||||
KGRQCQMQQLVDMAAQVAA-GMAYLESQNYIHRDLAARNVLVGEH---NICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVW

SFGVLLFELTTRGRAPYGNQSNPVVLQNIARGKTLQLPPSAPVSLHWLCAEIWVFEPEQRPSFEQIVEHLGGEL
|||.|| |. | || ||    |  ||| ...|  .  ||  |. |  .  | |  .|..|| || .   |   .
SFGILLTEIITYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF

Kinase RTKF2.AA SRM 662-927 38 2.5e-54 180.06 In-house 2-253 (253) Show / Hide
Range on Protein: 662-927
Range on HMM: 2-253/253
Sequence Identity: 38% (103 aa)

QLGEELGSGNFGRVLHGLWSQDKGSAIPVAIKFITTADGMDWRSQLLKEAVAMNTIGQHPHVIQLHGLLMTPFEDETVAFVMEFAAHGDLRSYLQR-EDV
 |.  ||.| || |  |||   ||. ..|||| |  .. |    .| ||  ||     | |.| ||         . |  . |  . | |  ||   .. 
TLCRKLGEGYFGEVWEGLW---KGQ-VHVAIKVIKRDNLMH-QHMLQKEIQAMKKL-RHKHIIRLHAVCSV---GDPVYIITELMRKGNLQQYLRDSDEK

EFGVAHTLQAAHQVVALALGFISKQGLVHRDVAARNVLVFEDQPTMLVKLTDFGLARVLSQHQEYYRSAQDDSLPFRWMAPEAITQRRFSEKSDVWSFGV
   . | |  | | ||  . .   |  .||| ||||||| ..    | |  |||||| .      |    |   |..| ||||.  | .| ||||||||.
ALPIPHLLDFACQ-VAEGMCYLEEQNYIHRDLAARNVLVGDN---NLCKVGDFGLARLI--KDDIYSPSHDHNIPYKWTAPEAANYRHYSQKSDVWSFGI

LLFELTTRGRAPYGNQSNPVVLQNIARGKTLQLPPSAPVSLHWLCAEIWVFEPEQRPSFEQIVEHLG
||.|. |.|  ||   .|   .| | ||  .  |   | . | |  | |  .|||||.| .  | | 
LLHEMFTYGQCPYPGMTNHETFQQIDRGYRMPCPAECPPEVHKLMLECWCRDPEQRPCFKDLREKLT

Kinase RTKF2.AA TK-Unique 775-926 34 1.4e-45 155.1 In-house 140-294 (294) Show / Hide
Range on Protein: 775-926
Range on HMM: 140-294/294
Sequence Identity: 34% (55 aa)

VALALGFISK--QGLVHRDVAARNVLVFEDQPTMLVKLTDFGLARVLSQHQEYYRSAQDDSLPFRWMAPEAIT--QRRF-SEKSDVWSFGVLLFELTTRG
.| .. ....  .. ||||..|||||. |      .|..|||.|| .. ...| .. .   .| ||||||..   .. . ..||||||||||..|. | |
IACGMEYLASQRKKIVHRDLCARNVLLTE---DKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLG

RAPYGNQSNPVVLQNIARGKTLQLPPSA-PVSLHWLCAEIWVFEPEQRPSFEQIVEHL
  ||.. ... ....| .|.....|..  .  .. |  . |  |||.||||.||.  |
ACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL

Kinase RTKF2.AA S_TKc 661-926 21 2.5e-41 144.54 SMART 1-231 (231) Show / Hide
Range on Protein: 661-926
Range on HMM: 1-231/231
Sequence Identity: 21% (60 aa)

VQLGEELGSGNFGRVLHGLWSQDKGSAIPVAIKFITTADGMDWRSQLLKEAVAMNTIGQHPHVIQLHGLLMTPFEDETVAFVMEFAAH--GDLRSYLQRE
 ......|.| ||.|  . .     .   |||| |          ....|   .    .||....|..   .    . . .|||.. .  |||..|... 
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKR

DVE-----FGVAHTLQAAHQVVALALGFISKQGLVHRDVAARNVLVFEDQPTMLVKLTDFGLARVLSQHQEYYRSAQDDSLPFRWMAPEAITQRRFSE-K
  .     |   |.   ..|.. .|| .. ..| .|||.   |.|. |      .|..||||||.|                  .|||| .    ..  |
GRHGLRFPFPE-HARFYMYQIC-CALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCK

SDVWSFGVLLFELTTRGRAPYGNQSNPVVLQNIARGKTLQLPPSAPVSLHWLCAEIWVFEPEQRPSFEQIVE-------H--L
.|.||.|..|.|. . |. |.    .. .. .. .          |  .. .   .....||.||.  .. .       |  .
CDWWSCGCILYEMLC-GYPPFP---QMQMMFKKIG---------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase RTKF2.AA Pkinase 661-926 22 4e-37 132.34 Pfam 1-293 (293) Show / Hide
Range on Protein: 661-926
Range on HMM: 1-293/293
Sequence Identity: 22% (69 aa)

VQLGEELGSGNFGRVLHGLWSQDKGSAIPVAIKFITTADGMDWRSQLLK---EAVAMNTIGQHPHVIQLHGLLMTPFEDETVAFVMEFAAHG----DLRS
 ..|. .|||.||.| .. .  .      ||.| |   .  .|  | .    |.  |. . .||....|..  ..   .  . .|||.. .|    || .
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED---KDHIYMVMEYCEGGLYVMDLFD

YLQ-REDVEF--GVAHTLQAAHQVVALALGFISKQGLVHRDVAARNVLVFEDQPTML---VKLTDFGLARVL-SQHQEYYRSAQDDSLPFRWMAPEAIT-
|.. ...  |     .    . |..  .| .. ..| .|||.   |.|.  |.   .   ||..|||||...   ... . .    .   ..|||| |  
YISTWRHGCFYFSEWECKFYMYQIL-RGLEYCHSMGIIHRDLKPENILI--DNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTP---WYMAPEVIRG

QRRFSEKSDVWSFGVLLFELTTRGRAPYGNQ----SNPVVLQNIARGKTLQLPPSAP-----------------------VSLHWLCAEIWVFEPEQRPS
..  . |.|.||.|..|.|. . || |. ..    .    .| |.| .  .|. . |                        ..  ..  .. . |..||.
GQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

FEQIVEH--L
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AEQILQHPWF

Kinase RTKF2.AA TK-Unique 661-757 26 4.2e-14 45.14 In-house 1-98 (294) Show / Hide
Range on Protein: 661-757
Range on HMM: 1-98/294
Sequence Identity: 26% (26 aa)

VQLGEELGSGNFGRVLHGLWSQDK---GSAIPVAIKFITTADGMDWRSQLLKEAVAMNTIGQHPHVIQLHGLLMTPFEDETVAFVMEFAAHGDLRSYLQR
. .|...|.|.|| | .|  ....   .  . ||.|          ....|||.  |. .|.||...|. |  ....  | .  .||... |.|..||..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD--EPWMIIMEYCPCGNLQHYLRT