Gene RTKL1 (M.brevicollis)

RTKL1

Species: M.brevicollis
Alias: RTKL1
External Links:
Annotation:

Classification

Group: TK
Family: RTKL

Sequence

Name Sequence Type Origin Length Description Download
RTKL1.AA Protein None 825 None Fasta, JSON
RTKL1.kin_dom Protein Kinase Domain None 214 None Fasta, JSON

Protein domain

Protein domains of RTKL1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RTKL1.AA RTKL 544-770 70 1.2e-232 623.19 In-house 1-227 (259) Show / Hide 
Range on Protein: 544-770
Range on HMM: 1-227/259
Sequence Identity: 70% (160 aa)

FILGNELGSGNFGRVVQASSCGAMVPTQVAIKIAHLIQSKNQTDAVLREALLLHTLEHPNIIAIYGCTLVEQRLAMVLELAPLGPLREYLRAPDGPGSGT
|||.||||.|.|.||.||.||..||||||||||||..|||||.||||.||.|||.|.||.||...|||.|.||.||.|||||.|.||||||..|.|.|..
FILENELGRGQFSRVYQARSCSRMVPTQVAIKIAHEQQSKNQMDAVLYEAVLLHQLHHPHIIQMHGCTAVPQRMAMILELAPNGNLREYLRHDDAPSSSW

PQAQRLSWLCQLASALAYLHQRPMIHRDLAARNALLVSEDVCKLSDFGLSRRLKTEEDYYRPQPNGDLPFRWMSLEGLNGKPHTLASDVWAFGVLAFEVL
||.|||.||||.|.||||.|||.|||||||.||.|||...|||||||||||||..|.||||||.|...||||||.|.|||||||.|||||||||...||.
PQRQRLQWLCQVAQALAYIHQRRMIHRDLASRNVLLVPMMVCKLSDFGLSRRLQNEQDYYRPQQNDHVPFRWMSPETLNGKPHTMASDVWAFGVVCYEVI

TGQVPYADTDPLQLRLFLDRGHRLRLP
||||||||||..|.   |    || ||
TGQVPYADTDMPQVVALLKNEGRLALP
Kinase RTKL1.AA TK 544-776 21 2.8e-77 258.46 In-house 1-445 (486) Show / Hide 
Range on Protein: 544-776
Range on HMM: 1-445/486
Sequence Identity: 21% (95 aa)

FILGNELGSGNFG---RVVQASSCGAM-----------------------VPTQVAIKIAHLIQSKNQTDAVL----------------REALLLHT--L
 .||..||.|.||   .| ..   | .                       ..|.||.|. ..  . .|..  .                .|. ...   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

EHPNIIAIYG-CTLVE-----------QRLAMVLELAPLGP----LREYLRAPDGPGSG-----------------------------------------
.||||. .|| || .|           . . .|.|..|.|     ||.|||. .....                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------TPQAQRLSWLCQLASALAYLHQRP------MIHRDLAARNALLVSEDV-----------CKLSDFG---
                                . .|.| . .|.|....|||...      ..|||||||| |. ...|           ||..|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRRLKTE-----------------------EDYYRPQPNGDLPFRWMSLEGLNGKP---------HTLASDVWAFGVLAFEVLT-GQVPYA---
     |.|..  .                       .|||| |..| ||.|||. | ||..          .| .||||.|||| .|..| ||.||.   
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

--------DTDPLQLRLFLDR------------GHRLRLPQ-DLAPP
        . |. ..  .| |            |.|.|.|| ...|.
SNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPD
Kinase RTKL1.AA Pkinase_Tyr 544-772 32 2.1e-71 242.43 Pfam 1-240 (270) Show / Hide 
Range on Protein: 544-772
Range on HMM: 1-240/270
Sequence Identity: 32% (78 aa)

FILGNELGSGNFGRVVQASSC--GAMVPTQVAIKIAHLIQSKNQ---TDAVLREALLLHTL-EHPNIIAIYGCTL-VEQR--LAMVLELAPLGPLREYLR
 ..| .||.|.||.|...     .    ..||.|.    ..  .    .. .||| ....|  ||||.  ||. .  ..   . .|.|..|.| |..|||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

APDGPGSGTPQAQRLSWLCQLASALAYLHQRPMIHRDLAARNALLVSEDVCKLSDFGLSRRLKTEEDYY-RPQPNGDLPFRWMSLEGLNGKPHTLASDVW
..  ..   .  . |..  | |....||.....||||||||| |. .. |.| .||||.| . ...||| | . .|.|| .||..| .| .  | .||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

AFGVLAFEVLT-GQVP-YADTDPLQLRLFL-DRGHRLRLPQD
.|||| .|..| |. | |.. .. ..  .. ..|.|.  |..
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN
Kinase RTKL1.AA TyrKc 544-814 31 8e-65 222.58 SMART 1-280 (280) Show / Hide 
Range on Protein: 544-814
Range on HMM: 1-280/280
Sequence Identity: 31% (93 aa)

FILGNELGSGNFGRVVQASSCGAMVPTQVAIKIAHLIQSKNQTDAVLREALLLHTL--EHPNIIAIYGCTLVE-------QRLAMVLELAPLGPLREYLR
  || .||.|.||.|...        .|||.|  .         . .||| ... |  .||||...||. . .       . | .|.|..|.| |..|||
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

APDGPGSGTPQAQRLSWLCQLASALAYLHQRPMIHRDLAARNALLVSEDVCKLSDFGLSRRLKTE------EDYYRPQ--PNGD--LPFRWMSLEGLNGK
.. .     . .. ||.  | |.  .|||... ||||||||| |. .. ..| ||||||| .. .      .||||..   .|.  || |||..| .| .
KHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

PHTLASDVWAFGVLAFEVLT-GQVPYAD-----TDPLQLRLFLDRGHRLRLPQDLAPPLTSFCQVAVGSFIYPYTDMPFLHWPSCRVGSSSSAGTI
  | .||||.|||. .|..| || || .      .. ... ....|.|.. |..   |  ||  |   . .|    .   . |..|   |     .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSF--VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RTKL1.AA UTK 544-777 31 1.3e-59 202.6 In-house 1-271 (296) Show / Hide 
Range on Protein: 544-777
Range on HMM: 1-271/296
Sequence Identity: 31% (86 aa)

FILGNELGSGNFGRVVQASS--CGAMVPT-QVAIKIAHLIQSKNQTDA----VLREAL---LLHTLE-HPNIIAIYGCTLVEQRLAMVLELAPLGPLREY
 .||..||.|.|| |  |.   |   ... .||.| .    ...|. .    ...||    ..  .. |||..  .|  . |. ...|.|... | || |
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LR-APDGPG-SGTPQA--QRLSWLCQLASALAYLHQRPMIHRDLAARNALLVSE-------DVCKLSDFG---LSRRLKT--------EEDYYRPQPNGD
|| ... |.  .. .   |||..  . |....|||..  .|||||||| |. .         |||..|||   .|||..|        | .||..|... 
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LPFRWMSLEGLNGK-PHTLASDVWAFGVLAFEVLT-GQVPYADTDPLQLRLFLDRGHRLRLPQ--DLAPPL
.|.|||. | |.    .|..||||.|||. .|..| |..||..    |. ... .| |.|.|.  |   |.
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPV
Kinase RTKL1.AA Ack 546-737 39 5.4e-54 180.51 In-house 3-199 (266) Show / Hide 
Range on Protein: 546-737
Range on HMM: 3-199/266
Sequence Identity: 39% (78 aa)

LGNELGSGNFGRVVQAS---SCGAMVPTQVAIKIAHLI--QSKNQTDAVLREALLLHTLEHPNIIAIYGCTLVEQRLAMVLELAPLGPLREYLRAPDGPG
|. .||.| || | ..    . |  .  |||.|.   .  |. |  |  |||.  .| |.||...  ||  |    | || ||||.| | . ||. . . 
LCEKLGDGCFGVVWRGEWTNPGGKHI--QVAVKCLRSDKMQQPNCMDDFLREVAIMHSLDHPHLVRLYGVVLDQPMLMMVTELAPCGSLLDCLRK-HCRT

SGTPQAQRLSWLCQLASALAYLHQRPMIHRDLAARNALLVSED-VCKLSDFGLSRRLKTEEDYYRPQPNG--DLPFRWMSLEGLNGKPHTLASDVWAFGV
. .. .  . .. |.|....||... .||||||||| || | |   | .||||.|.|. .||||| ...    .|| |.  | |. .  . |||||.|||
AFFLIHTLCDFCMQIAMGMRYLEMKRCIHRDLAARNILLFSDDRKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFGV
Kinase RTKL1.AA TK-Unique 544-771 28 5e-52 177.69 In-house 1-262 (294) Show / Hide 
Range on Protein: 544-771
Range on HMM: 1-262/294
Sequence Identity: 28% (74 aa)

FILGNELGSGNFGRVVQASSCGAM----VPTQVAIKIAHLIQSKNQTDAVLREALLLHTLE-HPNIIAIYGCTLVEQ-RLAMVLELAPLGPLREYLRAPD
. .|...|.|.|| |  .  .| .     ...||.|  .   .. . .. |.|. ..  |  ||||. ..||.   . .  ...| .| | |. |||   
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

GP--GS--------------GTPQAQRLS------WLCQLASALAYLHQRPM--IHRDLAARNALLVSEDVCKLSDFGLSRRLKTEEDYYRPQPNGDLPF
..  ..               .|.   .|      ...|.|....||.. ..  .||||.||| || .  |||..|||..|.. |...| . .  | .| 
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWMSLEGLN--GKPH-TLASDVWAFGVLAFEVLT-GQVPYADTDPLQLRLFLDRGHRLRLPQ
|||..| |   .... |  ||||.|||| .|..| |. || . .. ...  . .|.|. .|.
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPE
Kinase RTKL1.AA RTKF 544-776 37 5e-46 146.11 In-house 1-239 (272) Show / Hide 
Range on Protein: 544-776
Range on HMM: 1-239/272
Sequence Identity: 37% (90 aa)

FILGNELGSGNFGRVVQASSCGA-MVPTQVAIKIAHLIQSKNQTDAVLREALLLHTL-EHPNIIAIYG--CTLVEQ-RLAMVLELAPLGPLREYLRAPDG
  || .||.|.||||...       . . ||||  |     |   . |||. .. .  .|| || ..|   |  ||  .|.|.| || | .| ||   | 
IMLGEQLGHGHFGRVHHGYWRQQKGQRQPVAIKHIHTQDMMNWRRQMLRECCAMNRVGQHPHIIQFFGILMTPFEQNEMAFVMEFAPHGDMRRYLQQHD-

PGSGTPQAQRLSWLCQ-LASALAYLHQRPMIHRDLAARNALLVSED---VCKLSDFGLSRRLKTEEDYYRPQPNGDLPFRWMSLEGLNGKPHTLASDVWA
  .    |. |    | .|.|...  .. ..|||.|||| |   .      ||.|||| | |    ||||   | .||||||  |       |  |||| 
--VDLGRAHMLDAAHQVVAEAMVFISRQGLVHRDVAARNVLVFEDQPRMYVKLTDFGLARVLSQHQDYYRSMQNEELPFRWMAPEAIMHRRFTQKSDVWS

FGVLAFEVLT-GQVPYADTDPLQLRLFLDRGHRLRLPQDLAPP
||.. ||  | | |||.        .|  || .| .| . .||
FGMMLFELFTRGDVPYGNMPHPVVLQFIRRGKTLQMPDS-CPP
Kinase RTKL1.AA Fer 544-777 26 6.8e-46 154.32 In-house 1-256 (283) Show / Hide 
Range on Protein: 544-777
Range on HMM: 1-256/283
Sequence Identity: 26% (68 aa)

FILGNELGSGNFGRVVQA------SSCGAMVPTQVAIKIAHLIQSKNQTD---AVLREALLLHT-LEHPNIIAIYGCTLVEQRLAMVLELAPLGPLREYL
..||. ||.|.|| | ..         . .|...||.| . ..... ...    ...|| .. . . |||....||    || .  |.|... | |..||
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

RAPDGPGSGTPQAQRLSWLCQLASALAYLHQRPMIHRDLAARNALLVS-EDVCK--LSDFGLSRRLKTEEDYYRPQ-PNGDLPFRWMSLEGLNGKPHTLA
.  ..     . ....  . | |. ..|||.. .||||.|||| |.   ....|  .||||.|| .....  |.   .   .| ||.. | .. .  . .
KKNKNK--TVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPK

SDVWAFGVLAFEVLT-GQVPYAD----TDPLQL----RLFLDR-GHRLRLPQDLAPPL
.|||.|||...|. | |. ||..      . ..    |    . |.....|.  .|..
TDVWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEI
Kinase RTKL1.AA RTKA 544-784 29 6.6e-44 151.72 In-house 1-314 (314) Show / Hide 
Range on Protein: 544-784
Range on HMM: 1-314/314
Sequence Identity: 29% (93 aa)

FILGNELGSGNFGRVVQASSCGA-----MVPTQVAIKIAH--LIQSKNQTDAVLREALLLHTL-EHPNIIAIYGCTLVEQR------LAMVLELAPLGPL
.     .|.|.|..| |||   .       |. ||||  .   . .|    | .||..||| .  .|.||  .|  |          ..||.| .| | |
MQVRHVVGHGHFSQVYQASLQDMEDEMRQGPQCVAIKECDDLMLNDKTTLSAWMREIMLLHSMRDCPHIIGLHGVCLPREDKHHQSHCGMVCEWCPHGNL

REYLRA-P------------DGP---------GSGTPQAQRLSWLC----QLASALAYLHQRPMIHRDLAARNALLVSEDV---CKLSDFGLSRRLKTEE
|  .|  |                         | . . | |. .|    | |.|.||| ..  .|||.|||| |  |      ||| |||||| .   .
RDFVRQHPHFSAPVVATIAMQHSGEPNASPKLLSEAQCHQALLQMCPCWAQVAQAMAYLAKCGIVHRDVAARNVLVMSLQPAFHCKLADFGLSRVM-PSS

DYYRPQPNGDLPFRWMSLEGLNGKPHTLASDVWAFGVLAFEVLT-GQVPYA------------------------------DTDPLQLRLFLDRGHRLRL
|||.     ..||||| .| .  .    .||||.||||. |.|| ||.|..                              . |  ..   | .| .|..
DYYKSRADDEMPFRWMAPECIMERRYSEHSDVWSFGVLVWELLTHGQTPWQNCESHQIVALLMRGERLTFAPTINAALRDSGCDLHHIIQMLKQGQTLPM

PQDLAPPLTSFCQVA
|  . |.|  ||   
PPCCPPCLQRFCFWC
Kinase RTKL1.AA EGFR 544-771 33 6.7e-44 143.54 In-house 1-226 (258) Show / Hide 
Range on Protein: 544-771
Range on HMM: 1-226/258
Sequence Identity: 33% (79 aa)

FILGNELGSGNFGRV---VQASSCGAMVPTQVAIKIAHLIQSKNQTDAVLREALLLHTLEHPNIIAIYGCTLVEQRLAMVLELAPLGPLREYLRAP-DGP
. ..  |||| ||.|   .     |  |   ||||. .   ........|.||. .  ..||... . |  . .| . .|  . |.| | .|.|   |  
LKKVKVLGSGAFGTVYKGIWIPE-GENVKIPVAIKVLREQTGPKANEEMLDEAYVMASVDHPHLVRLLGVCMHSQ-MQLVTQYMPYGCLLDYVRQHKDNI

GSGTPQAQRLSWLCQLASALAYLHQRPMIHRDLAARNALLVSEDVCKLSDFGLSRRLKTEEDYYRPQPNGDLPFRWMSLEGLNGKPHTLASDVWAFGVLA
||     . | |  | |. . || .. |.|||||||| |. |    |  ||||.. |. .|. |. |  | .| .|| || .  . .| .||||..||  
GS----QHLLNWCVQIAKGMQYLEEHRMVHRDLAARNVLVKSPNHVKITDFGLAKLLEHDEKEYHAQ-GGKMPIKWMALECIHHRCYTHQSDVWSYGVTC

FEVLT-GQVPYADTDPLQLRLFLDRGHRLRLPQ
 |..| || ||.     .   .|..| ||  |.
WELMTFGQKPYDGIPAREIPDLLEKGERLPQPP
Kinase RTKL1.AA TKL 550-784 20 3.4e-40 139.84 In-house 1-343 (364) Show / Hide 
Range on Protein: 550-784
Range on HMM: 1-343/364
Sequence Identity: 20% (71 aa)

LGSGNFGRVVQASSCGAMVPTQ-------VAIKIAHLIQSKNQT--------------------------DAVLREALLLHTLEHPNIIAIYGCTLVEQR
.||| || | ..   |  .          ||.|. .  .... |                          .   .|..... | ||||. ..|. . .. 
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

-------------LAMVLELAPLGPLREYLRAPDGPGSGTPQAQRLSWLCQLASALAYLHQ--------RPMIHRDLAARNALLVSEDV-----------
             |..| |..| | |..||             ||..|  . |....|||.        .|.|||||  .| |. .              
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---CKLSDFGLSRRLKTEED---------------YYRPQPNGDL-PFRWMSLEGLNGK----------------PHTLASDVWAFGVLAFEVLTGQVPY
   ||..||||||.......                .| . .     .|||. | |.|.                . . ..||..||.. .|.||...||
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

ADTD-PLQL---------RLFLDRGHRLRLP---------QDLAPPLTSFCQVA
.| . . ..          .  |.|.|. .|         ..  . ..|... .
YDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLM
Kinase RTKL1.AA S_TKc 544-798 21 1.1e-34 122.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 544-798
Range on HMM: 1-231/231
Sequence Identity: 21% (59 aa)

FILGNELGSGNFGRVVQASSCGAMVPTQVAIKIAHLIQSKNQTDAVLREALLLHTLEHPNIIAIYGCTLVEQRLAMVLELAPL--GPLREYLRAPDGPG-
. .....|.| ||.| ..   .     .||||| .        . ..||  .|.   ||||. .|..    ..| ||.|...   | |..|..   ..| 
YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

-SGTPQAQRLSWLCQLASALAYLHQRPMIHRDLAARNALLVSEDVCKLSDFGLSRRLKTEEDYYRPQPNGDLPFRWMSLEGLNGKPHTL-ASDVWAFGVL
 .. |  .  ....|...||.|.|..  |||||   | || .  . |..||||.|.|                  .|. | |   ...  ..|.|..|..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

AFEVLTGQVPYADTDPLQLRLFLDRGHRLRLPQDLAPPLTSFCQVAVG---SFIYPYT-D-----MPFL
 .| |.|. |.  .. . ... .        ....   .   .|.      .     . .     .|..
LYEMLCGYPPFP-QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RTKL1.AA Pkinase 544-757 24 1.4e-33 119.86 Pfam 1-226 (293) Show / Hide 
Range on Protein: 544-757
Range on HMM: 1-226/293
Sequence Identity: 24% (57 aa)

FILGNELGSGNFGRVVQASSCGAMVPTQVAIKIAHLIQSKNQTD--AVL-REALLLHTLEHPNIIAIYGCTLVEQRLAMVLELAPLG----PLREYLR-A
. .|  .|||.||.| ..   |     .||.||  .   | . |  ... .|. ... | ||||. .|..   .... ||.|... |     | .|..  
YHIGRKIGSGSFGCVYKCHHKGTGK--IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

PDGPGSGTPQAQRLSWLCQLASALAYLHQRPMIHRDLAARNALLVSEDVC----KLSDFGLSRRLKTEEDYYRPQPNGDLPFRWMSLEGLN-GKPHTLAS
 .|. .  .  .  ... |....|.|.|..  |||||   | |.......    |..||||.. ...  .     . | .  ..|. | .. |.... ..
RHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTP--WYMAPEVIRGGQYYGPKV

DVWAFGVLAFEVLTGQVPYADT------DPLQL
|.|..|.. .|.|.|. |. .       |..|.
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQM