UTK03

Species: M.brevicollis
Alias: UTK03
External Links:
Annotation:

Classification

Group: TK
Family: UTK

Sequence

Name Sequence Type Origin Length Description Download
UTK03.AA Protein None 642 None Fasta, JSON
UTK03.kin_dom Protein Kinase Domain None 206 None Fasta, JSON

Protein domain

Protein domains of UTK03.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase UTK03.AA UTK 301-516 40 4.5e-106 358.71 In-house 57-296 (296) Show / Hide
Range on Protein: 301-516
Range on HMM: 57-296/296
Sequence Identity: 40% (98 aa)

AR---IMRAYAVPHHMNVLRFLGLCWDSETLMVVTEFCSRGSLQHVLRNARPSQGQDSPHLNLLDRIKMAADVARGMAYLANQEFVHRDLCARNCLVHEN
||   .| . .  .|.||||..|.|...| .|.|||....|.|...||..||.....  .|.| .|..||.|.||||.||... ||||||.|||||||..
ARELQMMKQFH--WHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMH

-------MTAKISGFD---ASTMVN---------QSPMDMQNGQNILNVRWMAPQVLTEA-RFSNKSDVWSFGVLLFECMTFASKPYADLSNGDVCHQRG
       |..||..|     | .||         .|.. |...|... .|||||..||.. ||..|||||||||...|..|....||...|| .|.|| .
RMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVC

FK---LTRSAWGTGMSSYRIMRSCWHMGPSSRPDFEDLLSAL
 .   . .. |. ... ||.|..|||. |. |||||||....
NGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM

Kinase UTK03.AA TK 301-516 20 6.9e-71 236.64 In-house 89-486 (486) Show / Hide
Range on Protein: 301-516
Range on HMM: 89-486/486
Sequence Identity: 20% (82 aa)

ARIMRAYA--VPHHMNVLRFLGLCWDSET------------LMVVTEFCSRGS----LQHVLRNARPSQGQDSP--------------------------
|..|      . || |..|..| | ..|.            .|.|.|... |.    |.. ||. ||   . ..                          
AEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSH

------------------------------------------HLNLLDRIKMAADVARGMAYLANQ------EFVHRDLCARNCLVHENMT---------
                                          .|.. ... |....|.||.||. .       ||||||.||||||.||..         
ESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCG

--AKISGFDAST-----MVNQSPMD-----MQNG----------------------QNILNVRWMAPQVLT---------EARFSNKSDVWSFGVLLFEC
  .||. |  |      .    . |     ....                      .  | .||||| .|.         . .|. ||||||||||..|.
PVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI

MTFASKPYAD-LSNGDVCH-----------------------QRGFKLTRS--AWGTG-------------MSSYRIMRSCWHMGPSSRPDFEDLLSAL
.|.. .||.  .|| ||..                       . | .. .   .  .                 |..|..|||  |. ||.|..|...|
FTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase UTK03.AA Pkinase_Tyr 279-475 34 2e-57 195.11 Pfam 30-227 (270) Show / Hide
Range on Protein: 279-475
Range on HMM: 30-227/270
Sequence Identity: 34% (70 aa)

QVAVKACSMPPGSPE--YSNFVIAARIMRAYAVPHHMNVLRFLGLCW-DSET--LMVVTEFCSRGSLQHVLRNARPSQGQDSPHLNLLDRIKMAADVARG
.|||| .     ...     |   |.||. .  .|| |..|..| |  ..|   ...|.|..  |.| . ||. |     | ..|.. | ..|....|.|
PVAVKMLKEGAMHEQNCREDFMREAKIMKQL--GHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR----EDKQPLTMKDLLQMCWQIAKG

MAYLANQEFVHRDLCARNCLVHENMTAKISGFDASTMVNQSPMD-MQNGQNILNVRWMAPQVLTEARFSNKSDVWSFGVLLFECMTFASKP-YADLSNGD
|.||... ..||||.||||||.||...||. |  .  .        . |   | ..|||| .. . .|. ||||||||||..| .|.  .| |...|| .
MEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEE

VCHQ
|...
VYEY

Kinase UTK03.AA TK-Unique 278-516 31 5.4e-55 188.06 In-house 31-294 (294) Show / Hide
Range on Protein: 278-516
Range on HMM: 31-294/294
Sequence Identity: 31% (83 aa)

KQVAVKACSMPPGSPEYSNFVIAARIMRAYAVPHHMNVLRFLGLCWDS-ETLMVVTEFCSRGSLQHVLRNARPS-----------------QGQDSPH-L
|.||||..  .    . ..|   ...|.  ... | |....|| | .| |  | . |.|..|.||| ||. ||                    ....  .
KCVAVKMLKDNATDTDKQDFLKEIQMMK--ELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPI

NLLDRIKMAADVARGMAYLAN--QEFVHRDLCARNCLVHENMTAKISGFDASTMVNQ-SPMDMQNGQNILNVRWMAPQVLT--EARF-SNKSDVWSFGVL
.. | .  | ..|.||.|||   ...|||||||||.|. |. ..||..|  .. |.   . .|. .|. . .||||| .|   .  . . ||||||||||
SPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVL

LFECMTFASKPYADLSNGDV--CHQRGFKLTRSAWGTGMSSYRIMRSCWHMGPSSRPDFEDLLSAL
..|..|. . || .... |.  | ..|. . . .       | .|.|||.  |..||.|..... |
MWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL

TyrKc UTK03.AA TyrKc 241-516 27 8.4e-54 185.98 SMART 1-280 (280) Show / Hide
Range on Protein: 241-516
Range on HMM: 1-280/280
Sequence Identity: 27% (89 aa)

LKALSK----------KSHADLFGGPRSSKRVRQELITEFDDWCLSSKQVAVKACSMPPGSPEYSNFVIAARIMRAY-AVPHHMNVLRFLGLCWDS----
.. . |          | ...                           ||||| .           |   ||||. .    || |..|..| | ..    
ITLGKKLGEGAFGEVYKGTWK--------------------------IQVAVKMLKEDA----REDFMREARIMCKLGG--HHPNIVRLYGVCTQQGRNF

---ETLMVVTEFCSRGSLQHVLRNARPSQGQDSPHLNLLDRIKMAADVARGMAYLANQEFVHRDLCARNCLVHENMTAKISGFDASTMVNQS-------P
   | ||.|.|... |.|.. ||. ||        |.. | .... ..|.||.||. . ..|||| ||||||.|| |.||| |  |  .           
MYIEPLMIVMEYMPHGDLKDYLRKHRPK-------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKD

MDMQ----NGQNILNVRWMAPQVLTEARFSNKSDVWSFGVLLFECMTFASKPYAD-----LSNGDVCH--QRGFKLTRSAWG-------TGMSSYRIMRS
. ..    .|   | .||||| .. . .|. |||||||||...| .|.  .|| .     .|| .| .  ..|. . . . .            |.||..
YYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQ

CWHMGPSSRPDFEDLLSAL
|||  |..|| |... . .
CWHEDPEDRPTFSEIHECF

Kinase UTK03.AA Abl 311-516 34 1.5e-44 146.21 In-house 53-252 (252) Show / Hide
Range on Protein: 311-516
Range on HMM: 53-252/252
Sequence Identity: 34% (72 aa)

HHMNVLRFLGLCWDSETLMVVTEFCSRGSLQHVLRNARPSQGQDSPHLNLLDRIKMAADVARGMAYLANQEFVHRDLCARNCLVHENMTAKISGFDASTM
.| |. . || |       ..||| . | |   ||..      |  .|. .  . ||. .| || || ...|.|||| |||||| |.   |.  |  . |
KHPNLVQLLGVCTREPPFYIITEFMCYGNLLDYLREC------DREELPAVVLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLARM

VNQSPMDMQNGQNILNVRWMAPQVLTEARFSNKSDVWSFGVLLFECMTFASKPY--ADLSNGDVCHQRGFKLTRSAWGTGMSSYRIMRSCWHMGPSSRPD
...     . |     ..| ||  |   .|| ||||| |||||.|  |.   ||   |||.     ..|... |   |   . |..|| ||.  .. || 
MKDDTYTAHAGAK-FPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATYGMSPYPGIDLSHVYHKLEKGYRMERPE-GCPPKVYELMRQCWQWSHTDRPS

FEDLLSAL
|...  |.
FKEIHHAM

Kinase UTK03.AA Src 312-516 36 2.3e-44 148.64 In-house 53-255 (255) Show / Hide
Range on Protein: 312-516
Range on HMM: 53-255/255
Sequence Identity: 36% (76 aa)

HMNVLRFLGLCWDSETLMVVTEFCSRGSLQHVLRNARPSQGQDSPHLNLLDRIKMAADVARGMAYLANQEFVHRDLCARNCLVHENMTAKISGFDASTMV
| .... .  | . |    |||. |.|||.  |..      ..  ||.| . | ||| ||.|||||  . ..|||| ||| || ||  .|.  |    ..
HEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK-----DGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLARLI

N--QSPMDMQNGQNILNVRWMAPQVLTEARFSNKSDVWSFGVLLFECMTFASKPYADLSNGDVCHQ--RGFKLTRSAWGTGMSSYR-IMRSCWHMGPSSR
        .. | . . ..|.||  ... ||. ||||||||.|| | .|.   ||   .| .|  |  ||... . .     . |  ||. |||  |  |
KEDDDEYCARHGAK-FPIKWTAPEAINYGRFTIKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHN-CPDELYEQIMLQCWHKDPEQR

PDFEDLLSAL
| || | . |
PTFEYLQWFL

Kinase UTK03.AA Musk 356-516 33 2.3e-44 144.35 In-house 121-282 (282) Show / Hide
Range on Protein: 356-516
Range on HMM: 121-282/282
Sequence Identity: 33% (54 aa)

PHLNLLDRIKMAADVARGMAYLANQEFVHRDLCARNCLVHENMTAKISGFDASTMVNQSPMDMQNGQNILNVRWMAPQVLTEARFSNKSDVWSFGVLLFE
| |. ... .||...| |||||    ||||||  ||||. |.|  ||. |  |  .        .. .   .|||.|  .   .|.  ||||..||.| |
PQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESIWYNQFTYESDVWAYGVCLWE

CMTFASKPYADLSNGDVCH--QRGFKLTRSAWGTGMSSYRIMRSCWHMGPSSRPDFEDLLSAL
   .|  ||  ..  .|    . |. |  .   . .. | .|| ||   |. || | ..   .
IFSYALQPYYGMTHEEVIYYIRQGNILS-CPENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI

Kinase UTK03.AA CTKA 311-516 35 1.1e-43 144.6 In-house 67-290 (290) Show / Hide
Range on Protein: 311-516
Range on HMM: 67-290/290
Sequence Identity: 35% (80 aa)

HHMNVLRFLGLCWDSETLMVVTEFCSRGSLQHVLRNARPSQGQDSP--------------HLNLLDRIKMAADVARGMAYLANQEFVHRDLCARNCLVHE
|| |||| ||.|  .. .  ..|. . | |. .||  ||  ||  |               .     . ||...| || |||   |||||| .||||.  
HHPNVLRLLGVCTQHKPWHMIMEHMQYGDLHCYLRACRPADGQVCPARARRSIPRSFHPIEVHAHEQVYMAMQIAAGMNYLAEMGFVHRDLACRNCLLGQ

NMTAKISGFDASTMVNQS-PMDMQNGQNILNVRWMAPQVLTEARFSNKSDVWSFGVLLFECMTFASKPYADLSNGDVC-----H-QRGFKLTRSAWGTGM
  . ||. |  .          .   | .. ||||||  | . .||  ||||.|||||.| |... ||.. .|   ||     |  |  .. |..  .  
YCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPWRHMSDQEVCQAYTSHGMRRLPVPRNCPQV--

SSYRIMRSCWHMGPSSRPDFEDLLSAL
  |  |  ||   |  || || |.  |
-LYHCMQECWKFEPNQRPTFETLQRML

Kinase UTK03.AA Frk 280-520 33 5.8e-43 146.58 In-house 26-260 (260) Show / Hide
Range on Protein: 280-520
Range on HMM: 26-260/260
Sequence Identity: 33% (81 aa)

VAVKACSMPPGSPEYSNFVIAARIMRAYAVPHHMNVLRFLGLCWDSETLMVVTEFCSRGSLQHVLRNARPSQGQDSPHLNLLDRIKMAADVARGMAYLAN
||||   . ||. .  .|.  |.||.      |  ...   .|   | ....||   .||||. |. |   .|.   ....   . ||| || ||||| .
VAVKT--LKPGTMDPNDFLREAQIMKKL---RHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQ-AINDKGR---QCQMQQLVDMAAQVAAGMAYLES

QEFVHRDLCARNCLVHENMTAKISGFDAST--MVNQSPMDMQNGQNILNVRWMAPQVLTEARFSNKSDVWSFGVLLFECMTFASKPYADLSNGDVCHQ--
| ..|||| ||| || |.   ||  |      |...  .     .  . ..| ||      .|. ||||||||.|| | .|.   ||. . | .| ..  
QNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIITYGRMPYPGMTNAEVLQMVD

RGFKLTRSAWGTGMSSYRIMRSCWHMGPSSRPDFEDLLSALSEEL
.|... . . .     | ||  |||  |  || || |   | . .
HGYRMPQPP-NCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF

Kinase UTK03.AA Tec 427-518 40 8.6e-26 87.15 In-house 162-254 (254) Show / Hide
Range on Protein: 427-518
Range on HMM: 162-254/254
Sequence Identity: 40% (38 aa)

VRWMAPQVLTEARFSNKSDVWSFGVLLFECMTFASKPYADLSNGDVCHQ--RGFKLTRSAWGTGMSSYRIMRSCWHMGPSSRPDFEDLLSALSE
|.| .| |.   |.| |||||.||||  |  .    ||  .|| .|  .  .|..| |      |. |.|| .||| .|  || |..||... |
VKWCPPEVFHYSRYSSKSDVWAFGVLMWEVFSCGKMPYENMSNSEVVEHVSQGHRLYRPHLCS-MHIYQIMYHCWHEKPEERPTFQQLLRQITE

Kinase UTK03.AA InsR 279-405 34 3.6e-23 74.57 In-house 33-163 (278) Show / Hide
Range on Protein: 279-405
Range on HMM: 33-163/278
Sequence Identity: 34% (46 aa)

QVAVKACSMPPGSPEYSNFVIAARIMRAYAVPHHMNVLRFLGLCWDSETLMVVTEFCSRGSLQHVLRNARPSQGQDSPHLN-------LLDRIKMAADVA
..|.|     . . |  .|   | .| .     . .| | || |   .  .|| |.  .| |   ||  || ...  | .|       | . . |||...
RCAIKTVNENASMRERIEFLNEASVMKEF---NCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRPEEEFNNPGCNRNQHVPCLDQMHQMAAEIC

RGMAYLANQEFVHRDLCARNCLVHENMTAKISGF
 ||||||   |||||| .|||.| .  | ||  |
DGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDF

Kinase UTK03.AA Tec 312-405 35 7.3e-19 62.59 In-house 53-141 (254) Show / Hide
Range on Protein: 312-405
Range on HMM: 53-141/254
Sequence Identity: 35% (33 aa)

HMNVLRFLGLCWDSETLMVVTEFCSRGSLQHVLRNARPSQGQDSPHLNLLDRIKMAADVARGMAYLANQEFVHRDLCARNCLVHENMTAKISGF
| .  .. | |     . .|||. ..|.|   ||  .   .. .  . .|  ..|  ||  |||||  . |.|||| |||||| ..   |.| |
HPKLVQLYGVCSQQRPIYIVTEYMEHGCLLNYLREHK---HHFQKNMAIL--LEMCQDVCEGMAYLERHCFIHRDLAARNCLVGDQCVVKVSDF

Kinase UTK03.AA InsR 427-472 54 8.5e-19 59.67 In-house 185-230 (278) Show / Hide
Range on Protein: 427-472
Range on HMM: 185-230/278
Sequence Identity: 54% (25 aa)

VRWMAPQVLTEARFSNKSDVWSFGVLLFECMTFASKPYADLSNGDV
||||||  |..  |. .||||||||.|.|  |... ||  |||  |
VRWMAPESLKDGVFTTHSDVWSFGVVLWEMVTLGEQPYQGLSNEQV

S_TKc UTK03.AA S_TKc 260-516 16 3.4e-14 31.16 SMART 1-231 (231) Show / Hide
Range on Protein: 260-516
Range on HMM: 1-231/231
Sequence Identity: 16% (47 aa)

KRVRQEL----------ITEFDDWCLSSKQVAVKACSMPPGSPEYSNFVIAARIMRAYAVPHHMNVLRFLGLCWDSETLMVVTEFCSR--GSLQHVLRNA
 .. ...           .. .    . ..||.|  .         ..    .|..     || |. .... . | . | .|.|.|.   |.| ..... 
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK--------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR

RP----SQGQDSPHLNLLDRIKMAADVARGMAYLANQEFVHRDLCARNCLVHENMTAKISGFDASTMVNQSPMDMQNGQNILNVRWMAPQVLTEARFSN-
..    ..      ..  .  .... ......|. .. ..||||   | |. |  . ||. |  .. .            .    .||| ||    ..  
GRHGLRFP------FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKC

KSDVWSFGVLLFECMTFASKPYADLSNGDVCHQRGFKLTRSAWGTGMSSYRIMRSCWHMGPSSRPDFEDLLS---------AL
|.|.||.|..|.|...    |.         .|. ||. .       .   ..| |... |. ||   ..|           .
KCDWWSCGCILYEMLC-GYPPFP-------QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase UTK03.AA Pkinase 311-458 22 7.5e-14 50.05 Pfam 58-207 (293) Show / Hide
Range on Protein: 311-458
Range on HMM: 58-207/293
Sequence Identity: 22% (37 aa)

HHMNVLRFLGLCWDSETLMVVTEFCSRG----SLQHVLRNARPSQGQDSPHL--NLLDRIKMAADVARGMAYLANQEFVHRDLCARNCLVHENMTA----
.| |..|... . |.  . .|.|.|  |    .| ....       ...  .     . ....  ..||..|. .. ..||||   |.|...|..     
NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACV

KISGFDAST---MVNQSPMDMQNGQNILNVRWMAPQVLT-EARFSNKSDVWSFGVLLFECMT
||. |  .      |.| |.   |      ..||| |.      . |.|.||.|..|.| ..
KICDFGLAKQFDY-NNS-MTTFCG----TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC

Kinase UTK03.AA Pkinase_Tyr 492-516 40 1.2e-07 26.56 Pfam 246-270 (270) Show / Hide
Range on Protein: 492-516
Range on HMM: 246-270/270
Sequence Identity: 40% (10 aa)

YRIMRSCWHMGPSSRPDFEDLLSAL
|..|..|||  |. || |..... |
YDLMKQCWHYDPEDRPTFSEIHEQL

Kinase UTK03.AA InsR 492-518 33 3e-07 20.28 In-house 252-278 (278) Show / Hide
Range on Protein: 492-518
Range on HMM: 252-278/278
Sequence Identity: 33% (9 aa)

YRIMRSCWHMGPSSRPDFEDLLSALSE
. .|. ||.  |. || | |... | .
QELMMMCWQYQPKMRPTFLDIIHYLCD

Kinase UTK03.AA Pkinase 494-516 24 1.231859 3.33 Pfam 269-293 (293) Show / Hide
Range on Protein: 494-516
Range on HMM: 269-293/293
Sequence Identity: 24% (6 aa)

IMRSCWHMGPSSRPDFEDLLSA--L
....|... |..|| .|..|    .
FIKWCLCKDPKKRPTAEQILQHPWF