Gene RTKA8 (M.brevicollis)

RTKA8

Species: M.brevicollis
Alias: RTKA8
External Links:
Annotation:

Classification

Group: TK
Family: RTKA

Sequence

Name Sequence Type Origin Length Description Download
RTKA8.AA Protein None 1116 None Fasta, JSON
RTKA8.kin_dom Protein Kinase Domain None 329 None Fasta, JSON

Protein domain

Protein domains of RTKA8.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LDLa RTKA8.AA LDLa 440-478 29 5e-06 27.28 SMART 1-47 (47) Show / Hide 
Range on Protein: 440-478
Range on HMM: 1-47/47
Sequence Identity: 29% (14 aa)

NCMSA--DELQAWGGEYIYPPQVCDGYQDCSNGRDE------NGCSA
 | .   .. |   |. |   .||||. ||..| ||       .|. 
TCPPDHPNQFQCGNGRCIPKSWVCDGDNDCGDGSDEWPFFDPENCPQ
Ldl_recept_a RTKA8.AA Ldl_recept_a 459-476 50 0.000518 14.96 Pfam 22-41 (41) Show / Hide 
Range on Protein: 459-476
Range on HMM: 22-41/41
Sequence Identity: 50% (10 aa)

QVCDGYQDCSNGRDE--NGC
.|||| .|| .| ||   .|
WVCDGDPDCHDGSDEWPENC
Kinase RTKA8.AA RTKA 723-1033 56 4.2e-229 767.4 In-house 1-314 (314) Show / Hide 
Range on Protein: 723-1033
Range on HMM: 1-314/314
Sequence Identity: 56% (177 aa)

FQVLEPVGEGHFSTVYKAAYQARPGKAMPDMPPFVALKEPK-LDLNEIGLLPEFLKEAMVLQAMGTHPHLIRLFGICLPRGD--HALRFAQVFEICDMGS
.||...||.||||.||.|..|... ..|...|..||.||.. |.||....|.....|.|.|..|...||.|.|.|.||||.|  |......|.|.|..|.
MQVRHVVGHGHFSQVYQASLQDME-DEMRQGPQCVAIKECDDLMLNDKTTLSAWMREIMLLHSMRDCPHIIGLHGVCLPREDKHHQSHCGMVCEWCPHGN

LKHVLTNSLAFSAPVVATIAMQASGEPNASPKLQRNDFEHRAFLQLIPCWAQVADVMTFLAERGIVHRDLAARNILVTSLQP-TLVKLADFGLSRVVSKE
|.........||||||||||||.||||||||||......|.|.||..|||||||..|..||..||||||.||||.||.|||| ...||||||||||....
LRDFVRQHPHFSAPVVATIAMQHSGEPNASPKLLSEAQCHQALLQMCPCWAQVAQAMAYLAKCGIVHRDVAARNVLVMSLQPAFHCKLADFGLSRVMPSS

DYYRSRSDDDLPFRWMAPEAIRELKFSEASDVWSFGVLLWEILNQGATPHSNCESHQIVALLMRGERLTFAPTINAALRDSNCESHQIVALLMRGERLTF
|||.||.||..||||||||.|.|...||.|||||||||.||.|..|.||..||||||||||||||||||||||||||||||.|..|.|...|..|..|..
DYYKSRADDEMPFRWMAPECIMERRYSEHSDVWSFGVLVWELLTHGQTPWQNCESHQIVALLMRGERLTFAPTINAALRDSGCDLHHIIQMLKQGQTLPM

APTINAALRDVSLAC
.|.....|......|
PPCCPPCLQRFCFWC
Kinase RTKA8.AA TK 723-1051 20 9.1e-83 277.17 In-house 1-486 (486) Show / Hide 
Range on Protein: 723-1051
Range on HMM: 1-486/486
Sequence Identity: 20% (105 aa)

FQVLEPVGEGHFS---TVYKAAYQARPGKAMPD-----------------MPPFVALKEPKLD-LNEIGLLPE-----------FLKEAMVLQAMGT---
 ....  |||.|    .|||. .. |... ...                  .  || |  |..  ..     .           ||.||.... |     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPHLIRLFGICLPRG--------DHALRFAQVFEICDMGS----LKHVLTNSLAFSAPVVATIAMQASGEPNAS-------------------------
 ||...||.|.|.  .        .|   .  | | .. |.    |.. | ..     .   ... | ...|. .                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----PKLQRNDFEHRAFLQ-----------------LIPCWAQVADVMTFLAER------GIVHRDLAARNILVTSLQPT---------LVKLADFG---
    .|.. ... .. .||                 |. . .|.|. | .|...      ..|||||||||.||..  ..          .|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSRVVSK------------------------EDYYRSRSDDDLPFRWMAPEAIR---------ELKFSEASDVWSFGVLLWEILNQGATPHSNCE
     |.| . .                        .||||..|.. ||.||||||...         . ||...|||||||||.|||.  |..|     
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

SHQIVALLMRGERLTFAPTINAALRDSNCESHQIVALLMR------------GERLTFA--PTIN--------------AALRDVSLACWHAQARHRPSF
|.| |.                     . . .... .| |            |.|.  .  |                 ... |. . |||.....||.|
SNQDVWKD-------------------G-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTF

AQLYQQL
.||..||
SQLHEQL
Kinase RTKA8.AA TyrKc 723-1051 25 1.1e-73 252.06 SMART 1-280 (280) Show / Hide 
Range on Protein: 723-1051
Range on HMM: 1-280/280
Sequence Identity: 25% (89 aa)

FQVLEPVGEGHFSTVYKAAYQARPGKAMPDMPPFVALKEPKLDLNEIGLLPEFLKEAMVLQAMG-THPHLIRLFGICLPR-------GDHALRFAQVFEI
 . ..  |||.| .|||. .              || |  | |      . .|..|| ..   |  ||...||.|.|.         . . .    |.| 
ITLGKKLGEGAFGEVYKGTWK-----------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMI----VMEY

CDMGSLKHVLTNSLAFSAPVVATIAMQASGEPNASPKLQRNDFEHRAFLQLIPCWAQVADVMTFLAERGIVHRDLAARNILVTSLQPTLVKLADFGLSRV
.. |.||. | ..                                    .|.    |.|. | .|......||||||||.||.. .   || .|||||| 
MPHGDLKDYLRKHRPK-----------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--TVKISDFGLSRD

VSKE-------DYYRSRS--DDD--LPFRWMAPEAIRELKFSEASDVWSFGVLLWEILNQGATPHSN-----CESHQIVALLMRGERLTFAPT---INAA
.  .       ||||...  . .  || ||||||.|.. ||...||||||||..|||.  |..|...     ..  ........|.|.   |    .   
IYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--

LRDSNCESHQIVALLMRGERLTFAPTINAALRDVSLACWHAQARHRPSFAQLYQQL
                      | ..  ... .. . |||...  ||.|.......
----------------------F-VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase RTKA8.AA Pkinase_Tyr 723-986 30 1.6e-65 222.53 Pfam 1-235 (270) Show / Hide 
Range on Protein: 723-986
Range on HMM: 1-235/270
Sequence Identity: 30% (82 aa)

FQVLEPVGEGHFSTVYKAAYQARPGKAMPDMPPFVALKEPKLDLNEIGL--LPEFLKEAMVLQAMGTHPHLIRLFGICLPRGDHALRFAQVFEICDMGSL
 . ..  |||.| .|||. .     .  ...|  || |    .        . .|..|| ..  .| ||...|| |.|...|..  .   |.| .  |.|
ITFGKKLGEGAFGEVYKGTWKG--DPDNTKIP--VAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDL

KHVLTNSLAFSAPVVATIAMQASGEPNASPKLQRNDFEHRAFLQLIPCWAQVADVMTFLAERGIVHRDLAARNILVTSLQPTLVKLADFGLSRVVSKEDY
.. | .                            .| ..    .|.   .|.|. | .|......||||||||.|||.  .  || .||||.| . ..||
LDYLRKHR--------------------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE--NNVVKICDFGLARDIYNDDY

Y-RSRSDDDLPFRWMAPEAIRELKFSEASDVWSFGVLLWEILNQGATP-HSNCESHQIVALL-MRGERL
| |.|.. .|| .|||||.|.. ||...|||||||||.|||.  |..|   ..  .......  .|.|.
YYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRM
Kinase RTKA8.AA UTK 723-986 26 1.2e-55 188.87 In-house 1-261 (296) Show / Hide 
Range on Protein: 723-986
Range on HMM: 1-261/296
Sequence Identity: 26% (77 aa)

FQVLEPVGEGHFSTVYKAAYQARPGKAMPDMPPFVALKEPKLDLNEIGLLP---EFLKEAM---VLQAMGTHPHLIRLFGICLPRGDHALRFAQVFEICD
 | ... |.|.| .|.|| .. ..   |..|   ||.|. . . .         .|..||    ....   ||...|| |.|.  .     .. | | . 
VQLGRQLGQGAFGEVHKARFT-QCSEHMYEM--DVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP----WMIVTEYME

MGSLKH-VLTNSLAFSAPVVATIAMQASGEPNASPKLQRNDFEHRAFLQ---LIPCWAQVADVMTFLAERGIVHRDLAARNILVTSLQ-----PTLVKLA
 |.| . . ... ..                           .....|    .. . ...|. | .|...|.|||||||||.||..        ...|.|
NGDLRSYLRRHRPTPP--------------------------ACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIA

DFG---LSRVVS---------KEDYYRSRSDDDLPFRWMAPEAIREL-KFSEASDVWSFGVLLWEILNQGATPHSNCESHQIVALLMRG--ERL
|||   .|| |.           .||.....| .|.|||||||. .  .|...||||||||..|||.  |..|  .   .|... ...|   |.
DFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRM
Kinase RTKA8.AA RTKF 870-987 49 3e-54 173.01 In-house 112-232 (272) Show / Hide 
Range on Protein: 870-987
Range on HMM: 112-232/272
Sequence Identity: 49% (60 aa)

AQ-VADVMTFLAERGIVHRDLAARNILVTSLQPTL-VKLADFGLSRVVSKE-DYYRSRSDDDLPFRWMAPEAIRELKFSEASDVWSFGVLLWEILNQGAT
.| ||  | |   .| ||||.||||.||   ||.. ||| |||| || |   ||||| ....|||||||||||   .|.. |||||||..|.|    |  
HQVVAEAMVFISRQGLVHRDVAARNVLVFEDQPRMYVKLTDFGLARVLSQHQDYYRSMQNEELPFRWMAPEAIMHRRFTQKSDVWSFGMMLFELFTRGDV

PHSNCESHQIVALLMRGERLT
|  | .   ...   || .|.
PYGNMPHPVVLQFIRRGKTLQ
Kinase RTKA8.AA CTKA 870-986 45 1.7e-46 154.14 In-house 138-255 (290) Show / Hide 
Range on Protein: 870-986
Range on HMM: 138-255/290
Sequence Identity: 45% (55 aa)

AQVADVMTFLAERGIVHRDLAARNILVTSLQPTLVKLADFGLSRVVSKE-DYYRSRSDDDLPFRWMAPEAIRELKFSEASDVWSFGVLLWEILNQGATPH
.|.|. | .|||.|.||||||.||.|.   |   .|.||||..|  . |  || . |   .|.|||||||... ||| |||||.||||||||.  | .| 
MQIAAGMNYLAEMGFVHRDLACRNCLLG--QYCHIKIADFGHGRTLRTESQYYYVSSQRVMPVRWMAPEALCFGKFSCASDVWAFGVLLWEIMSMGEKPW

SNCESHQIVALLMRG--ERL
       .. .   .  .||
RHMSDQEVCQAYTSHGMRRL
Kinase RTKA8.AA Src 852-986 40 8.9e-42 139.68 In-house 85-219 (255) Show / Hide 
Range on Protein: 852-986
Range on HMM: 85-219/255
Sequence Identity: 40% (56 aa)

LQ-RNDFEHRAFLQLIPCWAQVADVMTFLAERGIVHRDLAARNILVTSLQPTLVKLADFGLSRVVSK-EDYYRSRSDDDLPFRWMAPEAIRELKFSEASD
|. . .  |  . |||   ||||. | .| .. ..||||||||.||      ..| ||||| |.. . .| | .|..  .| .|.|||||.. .|.  ||
LKKDGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENN--VCKVADFGLARLIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSD

VWSFGVLLWEILNQGATPHSNCESHQIVALLMRGERL
|||||.||.||   | .|    . |. .  ..|| |.
VWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRM
Kinase RTKA8.AA Ack 871-987 46 1.2e-40 134.82 In-house 113-232 (266) Show / Hide 
Range on Protein: 871-987
Range on HMM: 113-232/266
Sequence Identity: 46% (56 aa)

QVADVMTFLAERGIVHRDLAARNILVTSLQPTLVKLADFGLSRV-VSKEDYYRSRSDD--DLPFRWMAPEAIRELKFSEASDVWSFGVLLWEILNQGATP
|.|. | .|  ....||||||||||. |    .|| .||||.|     |||||.       .|| |.|||..| ..|| |||||.||| |||    |  |
QIAMGMRYLEMKRCIHRDLAARNILLFSDD-RKVKICDFGLMRALGQNEDYYRMEFHRNLKVPFAWCAPECLRHRQFSHASDVWMFGVTLWEMFSYGEEP

HSNCESHQIVALLM-RGERLT
   |   ||  ..   ||||.
WAGCNGYQILQKIDKEGERLP
Kinase RTKA8.AA HMTK 870-987 41 3.5e-39 134.32 In-house 135-256 (291) Show / Hide 
Range on Protein: 870-987
Range on HMM: 135-256/291
Sequence Identity: 41% (52 aa)

AQVADVMTFLAERGIVHRDLAARNILVTSLQPTLVKLADFGLSRVVS-KEDYYRSRSDD-DLPFRWMAPEAIR--ELKFSEASDVWSFGVLLWEILNQGA
.|.|. |...|. . ||.||||||.||..    .||.|||||.| .   .||...|     || .||||||    .  |||.||||.|||..|||.  |.
VQCASGMAYIASQRMVHMDLAARNCLVGH--NNQVKIADFGLTRRLDPGQDYWHLRKHMVKLPIKWMAPEAMDGKRKIFSEKSDVWAFGVTMWEIWMYGE

TPHS--NCESHQIVALLMRGERLT
.| .    .. .. . ...| |||
QPYESQQIKNKEVQRHVREGRRLT
Kinase RTKA8.AA TK-Unique 871-986 40 1.7e-36 123.36 In-house 139-258 (294) Show / Hide 
Range on Protein: 871-986
Range on HMM: 139-258/294
Sequence Identity: 40% (49 aa)

QVADVMTFLAE--RGIVHRDLAARNILVTSLQPTLVKLADFGLSRVVSK-EDYYRSRSDDDLPFRWMAPEAIR--ELKF-SEASDVWSFGVLLWEILNQG
|.|  | .||.  ..||||||.|||.|.|.     .|..|||..| |.. ..| ...|   .| ||||||...  .  . .. |||||||||.|||.  |
QIACGMEYLASQRKKIVHRDLCARNVLLTE--DKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLG

ATPHSNCESHQIVALLMRGERL
|.| ..  . .|. .. .| |.
ACPYPGMPWKDIMECIRDGYRM
Kinase RTKA8.AA Met 871-986 37 2e-36 116.72 In-house 112-241 (271) Show / Hide 
Range on Protein: 871-986
Range on HMM: 112-241/271
Sequence Identity: 37% (49 aa)

QVADVMTFLAERGIVHRDLAARNILVTSLQPTLVKLADFGLSRVV-SKEDYYRSRSDDD---LPFRWMAPEAIR--------ELK-FSEASDVWSFGVLL
|||  |  .|..  ||||||.|| .        || |||||.| .     ||  ..  .   || .|||||  .          . |. .||||||||..
QVAKGMMYMASQKFVHRDLACRNCMLD--EHFTVKVADFGLCRDMDYDKEYYSQMHHTHPARLPVKWMAPECLQQGVCLGCPTYRQFTTKSDVWSFGVVM

WEILNQGATPHSNCES-HQIVALLMRG--ERL
|| .  ||.| ..  .   |   |  |   ||
WELMTRGAPPYPHVDNWFDITHWLHQGETRRL
Kinase RTKA8.AA S_TKc 723-1054 16 6.7e-21 76.67 SMART 1-231 (231) Show / Hide 
Range on Protein: 723-1054
Range on HMM: 1-231/231
Sequence Identity: 16% (58 aa)

FQVLEPVGEGHFSTVYKAAYQARPGKAMPDMPPFVALKEPKLDLNEIGLLPEFLKEAMVLQAMGTHPHLIRLFGICLPRGDHALRFAQVFEICDM--GSL
...|...|.| |..|||.                ||.|. |           ...|  .|.    ||....|....        ..  |.| ||   |.|
YEILRKIGKGAFGKVYKCRHKK--------TGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDL

KHVLTNSLA------FSAPVVATIAMQASGEPNASPKLQRNDFEHRAFLQLIPCWAQVADVMTFLAERGIVHRDLAARNILVTSLQPTLVKLADFGLSRV
.... .         |.  ... ..                              .|... . .. ..||.||||   |||...     .|..||||.|.
FDYIKKRGRHGLRFPFPE-HARFYM------------------------------YQICCALEYCHSHGIIHRDLKPENILLDE----HIKICDFGLARQ

VSKEDYYRSRSDDDLPFRWMAPEAIRELKFSE-ASDVWSFGVLLWEILNQGATPHSNCESHQIVALLMRGERLTFAPTINAALRDSNCESHQIVALLMRG
.         .       .|||| .   ...  ..|.||.|..|.| |  | .| .     |. ... .                               
L---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG-----------------------------

ERLTFAPTINAALRDVSLACWHAQARHRPSFAQLYQ------QLQGL
            ..|    |..   ..||.  .. |      . . .
---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase RTKA8.AA Pkinase 881-984 28 2.4e-14 51.83 Pfam 126-234 (293) Show / Hide 
Range on Protein: 881-984
Range on HMM: 126-234/293
Sequence Identity: 28% (32 aa)

ERGIVHRDLAARNILVTSLQPTL---VKLADFGLSRVVSKEDYYRSRSDDDLPFRWMAPEAIR-ELKFSEASDVWSFGVLLWEILNQGATPHSNC-----
..||.||||   |||.   ....   ||..||||..... .  ..  ..     ..|||| ||   . . ..|.||.|..|.| |. | .| ...     
SMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN

-ESHQIVALLMRGE
 .  |.... |...
HDQMQMICRIMGPP
Kinase RTKA8.AA Pkinase 723-841 19 1.1e-12 45.96 Pfam 1-116 (293) Show / Hide 
Range on Protein: 723-841
Range on HMM: 1-116/293
Sequence Identity: 19% (25 aa)

FQVLEPVGEGHFSTVYKAAYQARPGKAMPDMPPFVALKEPKLDLNEIGLLPEFLK--EAMVLQAMGTHPHLIRLFGICLPRGDHALRFAQVFEICDMG--
.......|.| |..|||.  .  .          ||.|. |.. .. . . . ..  |. ... .  ||. .||....   .||      |.| |..|  
YHIGRKIGSGSFGCVYKCHHKGTGK--------IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-KDHIY---MVMEYCEGGLY

--SLKHVLT--NSLAF--SAPVVATIAMQ
  .|.....  .. .|  |  ..  .. |
VMDLFDYISTWRHGCFYFSEWECKFYMYQ
Kinase RTKA8.AA Met 724-800 27 3.8e-08 22.48 In-house 1-72 (271) Show / Hide 
Range on Protein: 724-800
Range on HMM: 1-72/271
Sequence Identity: 27% (22 aa)

QVLEPVGEGHFSTVYKAAYQARPGKAMPDMPPFVALKEPKLD---LNEIGLLPEFLKEAMVLQAMGTHPHLIRLFGICLP
 .....| |||  ||.. |    |.  .     .| |   |      .|.   .||.|...   .  ||.   | ||||.
HFDDVIGQGHFGCVYHGMYHDNDGNEHH-----CACKS--LHGERITDIQHISQFLREGIMMKHF-DHPNVLSLIGICLD
Kinase RTKA8.AA UTK 1004-1051 24 4.2e-08 23.83 In-house 247-296 (296) Show / Hide 
Range on Protein: 1004-1051
Range on HMM: 247-296/296
Sequence Identity: 24% (12 aa)

HQIVALLMRG--ERLTFAPTINAALRDVSLACWHAQARHRPSFAQLYQQL
.|... ...|   |.   .   ... .. ..|||.  . ||.| .|.||.
MQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase RTKA8.AA TK-Unique 723-827 24 2.1e-07 21.7 In-house 1-99 (294) Show / Hide 
Range on Protein: 723-827
Range on HMM: 1-99/294
Sequence Identity: 24% (26 aa)

FQVLEPVGEGHFSTVYKAAYQARPGKAMPDMPP-FVALKEPKLDLNEIGL-LPEFLKEAMVLQAMGTHPHLIRLFGICLPRGDHALRFAQVFEICDMGSL
. |.. .||| |..|... .  ..   ...  .  ||.|  .|  |. ..   .||||. .... | ||......|.|   .    ..  ..| | .|.|
LEVGDVIGEGAFGQVWRGEVWGIW---KHWDKQKCVAVK--MLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD---EPWMIIMEYCPCGNL

KHVLTNS
 | | ..
QHYLRTC
Kinase RTKA8.AA CTKA 723-799 32 5.2e-07 19.44 In-house 1-79 (290) Show / Hide 
Range on Protein: 723-799
Range on HMM: 1-79/290
Sequence Identity: 32% (26 aa)

FQVLEPVGEGHFSTVYKAAYQARPG--KAMPDMPPFVALKEPKLDLNEIGLLPEFLKEAMVLQ-AMGTHPHLIRLFGICL
 ..   .||||.  |..|    .|   ||       ||.|  | . .| .   .|| || ||      ||  .|| |.|.
HCIMFKIGEGHYGQVFRAWLMPDPDDFKAQRKKGKDVAVKMLKDHATE-EDRRAFLHEAFVLSSEHFHHPNVLRLLGVCT
Kinase RTKA8.AA RTKF 723-797 26 6.6e-07 18.01 In-house 1-69 (272) Show / Hide 
Range on Protein: 723-797
Range on HMM: 1-69/272
Sequence Identity: 26% (21 aa)

FQVLEPVGEGHFSTVYKAAYQARPGKAMPDMPPFVALKEPKLDLNEIGLL---PEFLKEAMVLQAMGTHPHLIRLFGI
 .. | .| ||| .| ..   .  | . |     || |      .  ..     . |.|.  .   | ||| |..|||
IMLGEQLGHGHFGRVHHGYWRQQKGQRQP-----VAIKH----IHTQDMMNWRRQMLRECCAMNRVGQHPHIIQFFGI
Kinase RTKA8.AA Met 1028-1045 55 2e-06 16.81 In-house 254-271 (271) Show / Hide 
Range on Protein: 1028-1045
Range on HMM: 254-271/271
Sequence Identity: 55% (10 aa)

DVSLACWHAQARHRPSFA
|| |.||||..  ||.| 
DVMLCCWHANPEDRPQFS
Kinase RTKA8.AA Ack 723-838 25 5e-06 16.34 In-house 1-107 (266) Show / Hide 
Range on Protein: 723-838
Range on HMM: 1-107/266
Sequence Identity: 25% (30 aa)

FQVLEPVGEGHFSTVYKAAYQARPGKAMPDMPPFVALKEPKLD-LNEIGLLPEFLKEAMVLQAMGTHPHLIRLFGICLPRGDHALRFAQVFEICDMGSLK
  ..|  |.| |  | ..   .  ||  .     || |  . | ..  . . .||.|. .. ..  ||||.||.|. |   |  .    |.| .  ||| 
ITLCEKLGDGCFGVVWRGEWTNPGGKHIQ-----VAVKCLRSDKMQQPNCMDDFLREVAIMHSL-DHPHLVRLYGVVL---DQPM-LMMVTELAPCGSLL

HVLTNSLAFSAPVVATI
  |.  .  . . ..|.
DCLRKHCRTAFFLIHTL
Kinase RTKA8.AA Pkinase_Tyr 1031-1051 38 7e-06 20.53 Pfam 250-270 (270) Show / Hide 
Range on Protein: 1031-1051
Range on HMM: 250-270/270
Sequence Identity: 38% (8 aa)

LACWHAQARHRPSFAQLYQQL
. |||... .||.|.....||
KQCWHYDPEDRPTFSEIHEQL
Kinase RTKA8.AA HMTK 1010-1050 34 1e-05 16.05 In-house 249-291 (291) Show / Hide 
Range on Protein: 1010-1050
Range on HMM: 249-291/291
Sequence Identity: 34% (15 aa)

LMRGERLT-FAPT-INAALRDVSLACWHAQARHRPSFAQLYQQ
...| |||   |.  .. . |.  .|||.. . ||.|||| . 
VREGRRLTQPPPDDCPDDFWDLMCTCWHKDPHQRPTFAQLQKM
Kinase RTKA8.AA Src 1031-1051 42 1.2e-05 15.06 In-house 235-255 (255) Show / Hide 
Range on Protein: 1031-1051
Range on HMM: 235-255/255
Sequence Identity: 42% (9 aa)

LACWHAQARHRPSFAQLYQQL
| |||.... || |. |.. |
LQCWHKDPEQRPTFEYLQWFL
Kinase RTKA8.AA Ack 1031-1051 33 1.4e-05 14.78 In-house 246-266 (266) Show / Hide 
Range on Protein: 1031-1051
Range on HMM: 246-266/266
Sequence Identity: 33% (7 aa)

LACWHAQARHRPSFAQLYQQL
. || ...  ||.|.... ||
MQCWQHHPADRPTFSAIRDQL
Kinase RTKA8.AA TK-Unique 1033-1051 42 3.4e-05 13.98 In-house 276-294 (294) Show / Hide 
Range on Protein: 1033-1051
Range on HMM: 276-294/294
Sequence Identity: 42% (8 aa)

CWHAQARHRPSFAQLYQQL
||.  . .||||.|. ..|
CWQWEPEERPSFRQIKHRL
Kinase RTKA8.AA HMTK 774-799 46 0.000194 11.5 In-house 70-94 (291) Show / Hide 
Range on Protein: 774-799
Range on HMM: 70-94/291
Sequence Identity: 46% (12 aa)

EFLKEAMVLQAMGTHPHLIRLFGICL
||| || |...   ||.|..| | |.
EFLREAEVMCQL-RHPNLVQLVGVCM
Kinase RTKA8.AA CTKA 1033-1051 36 0.001846 7.33 In-house 272-290 (290) Show / Hide 
Range on Protein: 1033-1051
Range on HMM: 272-290/290
Sequence Identity: 36% (7 aa)

CWHAQARHRPSFAQLYQQL
||      ||.|..|   |
CWKFEPNQRPTFETLQRML
Kinase RTKA8.AA Src 775-798 33 0.047867 2.69 In-house 41-63 (255) Show / Hide 
Range on Protein: 775-798
Range on HMM: 41-63/255
Sequence Identity: 33% (8 aa)

FLKEAMVLQAMGTHPHLIRLFGIC
||.|| ..  .  |..|..|. .|
FLQEAQIMKKL-RHEKLVQLYAVC
Kinase RTKA8.AA Src 723-743 19 0.252391 0.2 In-house 1-21 (255) Show / Hide 
Range on Protein: 723-743
Range on HMM: 1-21/255
Sequence Identity: 19% (4 aa)

FQVLEPVGEGHFSTVYKAAYQ
.. ..  |.|.|  |... ..
IKLCRKLGQGQFGEVWMGYWN