23193

Species: M.brevicollis
Alias: 23193
External Links:
Annotation:

Classification

Group: TK-assoc
Family: SH2
Subfamily: Chimera

Sequence

Name Sequence Type Origin Length Description Download
23193.AA Protein None 2199 None Fasta, JSON

Protein domain

Protein domains of 23193.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
GCC2_GCC3 23193.AA GCC2_GCC3 511-549 38 0.001223 14.8 Pfam 1-37 (49) Show / Hide
Range on Protein: 511-549
Range on HMM: 1-37/49
Sequence Identity: 38% (16 aa)

GTYHDMVR--CLSCGAGTYQDSASHLSTSCKPKSRCPAG-TY
|||..     | .|. ||||.... .  ||.|   ||.| |.
GTYYNKGQNPCEPCPRGTYQNEEGQD--SCIP---CPPGKTT

GCC2_GCC3 23193.AA GCC2_GCC3 553-582 29 0.004375 13.0 Pfam 1-29 (49) Show / Hide
Range on Protein: 553-582
Range on HMM: 1-29/49
Sequence Identity: 29% (9 aa)

GGSSSSNT-NCLACPAGSYQDATNHLETSCK
|  ..... .| .|| |.||.  . .  ||.
GTYYNKGQNPCEPCPRGTYQNEEGQD--SCI

TNFR 23193.AA TNFR 522-562 30 0.006346 16.53 SMART 1-50 (50) Show / Hide
Range on Protein: 522-562
Range on HMM: 1-50/50
Sequence Identity: 30% (15 aa)

CG--AGTYQDSASHLS--TSCKPKS--RCPA---GTYDANGGSSSSNTNC
|   .|.|... .|..    |.| .  |||    |.|    ... ||| |
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC

TNFR 23193.AA TNFR 565-606 26 0.007584 15.72 SMART 1-50 (50) Show / Hide
Range on Protein: 565-606
Range on HMM: 1-50/50
Sequence Identity: 26% (13 aa)

CP--AGSYQDATNHLE--TSCKTKT-NTCPV---GHYASNGGSTTSDRIC
|.  .| |..  ||.     |.  .  .||    |.|..  .. ||...|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC

FU 23193.AA FU 474-528 28 0.016496 12.25 SMART 1-48 (48) Show / Hide
Range on Protein: 474-528
Range on HMM: 1-48/48
Sequence Identity: 28% (16 aa)

DGSCDWVVGSCDDSCDSSCACNSGLDTVNDVCSTCGKGTYHDM-VRCLS-CGAGTYQ
|| |      |...|..   |..     .| |..| .| |..   .|.| | .|.| 
DGVC----KPCHPECAT--GCWGPG---PDQCTSCPHGYYLHHNGTCVSQCPPGYYP

TNFR_c6 23193.AA TNFR_c6 565-606 32 0.041155 10.65 Pfam 1-41 (41) Show / Hide
Range on Protein: 565-606
Range on HMM: 1-41/41
Sequence Identity: 32% (15 aa)

CPAG-SYQDATNHLE--TSCKTKTNTCPV-GHYASNGGSTTSDRIC
|| | .|.| .||..  .|| |.   |.  |.|..     |... |
CPPGKTYTD-WNHVPHCLSC-TR---CHPMGQYMVQPCTWTQNTVC

TNFR 23193.AA TNFR 609-650 18 0.049208 7.22 SMART 1-50 (50) Show / Hide
Range on Protein: 609-650
Range on HMM: 1-50/50
Sequence Identity: 18% (9 aa)

CP--DGTWMNINGNSA--QQCYQKS-VPCSP---GQEVSNKGDKTADNIC
|.  .|.  . ....    .| . .  .|.|   ||...  ...| . .|
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC

TNFR_c6 23193.AA TNFR_c6 522-562 32 0.365443 7.41 Pfam 1-41 (41) Show / Hide
Range on Protein: 522-562
Range on HMM: 1-41/41
Sequence Identity: 32% (14 aa)

CGAG-TYQDSASHLSTSCKPKSRCPA-GTYDANGGSSSSNTNC
|  | ||.|   |    |.. .||.  |.|      . .|| |
CPPGKTYTD-WNH-VPHCLSCTRCHPMGQYMVQPCTWTQNTVC

GCC2_GCC3 23193.AA GCC2_GCC3 588-613 37 1.353848 4.9 Pfam 14-36 (49) Show / Hide
Range on Protein: 588-613
Range on HMM: 14-36/49
Sequence Identity: 37% (10 aa)

CPVGHYASNGGSTTSDRICAVCPDG-T
|| | | ...|..     |  ||.| |
CPRGTYQNEEGQD----SCIPCPPGKT

NCD3G 23193.AA NCD3G 562-594 27 1.388515 3.7 Pfam 28-54 (54) Show / Hide
Range on Protein: 562-594
Range on HMM: 28-54/54
Sequence Identity: 27% (9 aa)

CLACPAGSYQDATNHLETSCKTKTNTCPVGHYA
|. ||.|.|.. |.  ...|.    .|| ....
CIPCPEGEYSNTTD--SYTCT----PCPEDQWP

GCC2_GCC3 23193.AA GCC2_GCC3 648-663 37 5.819585 2.84 Pfam 9-24 (49) Show / Hide
Range on Protein: 648-663
Range on HMM: 9-24/49
Sequence Identity: 37% (6 aa)

NICAACSSNSYQPSQG
|.| .|  ..||.. |
NPCEPCPRGTYQNEEG

TNFR_c6 23193.AA TNFR_c6 609-650 27 17.486105 1.67 Pfam 1-41 (41) Show / Hide
Range on Protein: 609-650
Range on HMM: 1-41/41
Sequence Identity: 27% (12 aa)

CPDG-TWMNINGNSAQQCYQKSVPCSP-GQEVSNKGDKTADNIC
||.| |      | . .| .   .|.| ||...   ..| .  |
CPPGKTYTD--WNHVPHCLSC-TRCHPMGQYMVQPCTWTQNTVC

TNFR_c6 23193.AA TNFR_c6 653-670 15 46.408968 0.22 Pfam 1-18 (41) Show / Hide
Range on Protein: 653-670
Range on HMM: 1-18/41
Sequence Identity: 15% (3 aa)

CSSN-SYQPSQGLAVQCTR
|. . .|.  .. . .|..
CPPGKTYTD-WNHVPHCLS

NCD3G 23193.AA NCD3G 675-688 50 18.914199 0.33 Pfam 31-44 (54) Show / Hide
Range on Protein: 675-688
Range on HMM: 31-44/54
Sequence Identity: 50% (7 aa)

CKAGEYVTNPDSLT
|..|||. ..|| |
CPEGEYSNTTDSYT

NCD3G 23193.AA NCD3G 700-723 33 1e-05 18.93 Pfam 31-54 (54) Show / Hide
Range on Protein: 700-723
Range on HMM: 31-54/54
Sequence Identity: 33% (8 aa)

CAAGNYQASAGQTSCLPCPVDSYS
|..| |. . . ..|.||| | ..
CPEGEYSNTTDSYTCTPCPEDQWP

GCC2_GCC3 23193.AA GCC2_GCC3 699-734 40 0.000244 17.08 Pfam 13-49 (49) Show / Hide
Range on Protein: 699-734
Range on HMM: 13-49/49
Sequence Identity: 40% (15 aa)

ACAAGNYQASAGQTSCLPCPVD-SYSDTSAATSCKPC
.|  | || ..||.||.|||.  .. |. ..|| . |
PCPRGTYQNEEGQDSCIPCPPGKTTTDYPGSTSESDC

TNFR_c6 23193.AA TNFR_c6 700-717 30 0.558761 6.78 Pfam 1-19 (41) Show / Hide
Range on Protein: 700-717
Range on HMM: 1-19/41
Sequence Identity: 30% (6 aa)

CAAG-NYQASAGQ-TSCLPC
|. |  |..  ..   ||.|
CPPGKTYTD-WNHVPHCLSC

GCC2_GCC3 23193.AA GCC2_GCC3 789-821 33 9.9e-08 28.11 Pfam 1-33 (49) Show / Hide
Range on Protein: 789-821
Range on HMM: 1-33/49
Sequence Identity: 33% (11 aa)

GKYSLASASVCSACPAGTYSELAQASACTQCPA
| |. .. . |..|| ||| . ..  .|  ||.
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPCPP

NCD3G 23193.AA NCD3G 766-792 33 7e-05 16.46 Pfam 28-54 (54) Show / Hide
Range on Protein: 766-792
Range on HMM: 28-54/54
Sequence Identity: 33% (9 aa)

CIPCAAGKYQGQPYSTVCIDCAAGKYS
||||..| |. .. |. |..|  . ..
CIPCPEGEYSNTTDSYTCTPCPEDQWP

GCC2_GCC3 23193.AA GCC2_GCC3 822-858 34 0.000297 16.8 Pfam 1-37 (49) Show / Hide
Range on Protein: 822-858
Range on HMM: 1-37/49
Sequence Identity: 34% (13 aa)

GKFSASENSISCARCSAGTYQAQAGQSDCQTCQAG-YT
| .. ...   |  |  |||| ..||  |  | .|  |
GTYYNKGQ-NPCEPCPRGTYQNEEGQDSCIPCPPGKTT

HYR 23193.AA HYR 867-944 27 0.000557 15.13 Pfam 1-86 (86) Show / Hide
Range on Protein: 867-944
Range on HMM: 1-86/86
Sequence Identity: 27% (24 aa)

TDVTPPELTLAPNA---IVRFEALTNTFVYPTVTATDTSG-ERIVVTHTNNVQPD--EVG-TYDVTYSGEDSAKNKG-VLVVQVII
.| |||  .  ||     | .. .|    ....||||.||   .... ... . |   || ...|||  .|.| |..   ...| .
VDTTPPTVENCPNNIFRTVELGTSTVNVFWTEPTATDNSGDIQANLISRTAQPGDFFPVGEQTTVTYTFQDNAGNQADTCTFTVTV

NCD3G 23193.AA NCD3G 799-825 37 0.001059 12.96 Pfam 28-54 (54) Show / Hide
Range on Protein: 799-825
Range on HMM: 28-54/54
Sequence Identity: 37% (10 aa)

CSACPAGTYSELAQASACTQCPAGKFS
|. ||.|.||    .  || || .  .
CIPCPEGEYSNTTDSYTCTPCPEDQWP

TNFR 23193.AA TNFR 819-850 20 0.031832 9.2 SMART 1-50 (50) Show / Hide
Range on Protein: 819-850
Range on HMM: 1-50/50
Sequence Identity: 20% (10 aa)

CP--AGKFSASEN-----S--ISCA--RCSA---GTYQAQAGQS----DC
|.  .| .....|     .   .|   ||.    |.|  | ...     |
CKCQEGHYCHHWNHTHYEPHCLPCRHTRCPPEHMGQYMKQPCTATSNTVC

FU 23193.AA FU 747-808 20 0.051589 6.31 SMART 1-48 (48) Show / Hide
Range on Protein: 747-808
Range on HMM: 1-48/48
Sequence Identity: 20% (13 aa)

QTSCDGCGVGSRLDLTTSSCIP-CAAGKYQGQPYSTVCIDCAAGKYSLASASVCSA-CPAGTYS
.. |  |          ..|   |   .       . |. |. |.| .   ..| . ||.|.| 
DGVCKPCH---------PECATGCWGPG------PDQCTSCPHGYYLHHN-GTCVSQCPPGYYP

FU 23193.AA FU 813-876 18 0.122139 1.82 SMART 1-48 (48) Show / Hide
Range on Protein: 813-876
Range on HMM: 1-48/48
Sequence Identity: 18% (12 aa)

ASACTQCPAGKFSASENSISCAR-CSAGTYQAQAGQSDCQTCQAGYTVNPDFTQCTDVTPPELTL
.. |  |            .||  |.  .      . .|..|  ||  ...  .| .  ||    
DGVCKPCH----------PECATGCWGPG------PDQCTSCPHGYYLHHN-GTCVSQCPPGYYP

GCC2_GCC3 23193.AA GCC2_GCC3 756-786 32 0.260116 7.23 Pfam 1-31 (49) Show / Hide
Range on Protein: 756-786
Range on HMM: 1-31/49
Sequence Identity: 32% (10 aa)

GSRLDLTTSSCIPCAAGKYQGQPYSTVCIDC
|  ..  .. |.||  | || .  .. || |
GTYYNKGQNPCEPCPRGTYQNEEGQDSCIPC

TNFR_c6 23193.AA TNFR_c6 802-819 36 0.543899 6.82 Pfam 1-19 (41) Show / Hide
Range on Protein: 802-819
Range on HMM: 1-19/41
Sequence Identity: 36% (7 aa)

CPAG-TYSELAQASACTQC
|| | ||.. .... |..|
CPPGKTYTDWNHVPHCLSC

NCD3G 23193.AA NCD3G 833-853 28 0.596488 4.79 Pfam 28-48 (54) Show / Hide
Range on Protein: 833-853
Range on HMM: 28-48/54
Sequence Identity: 28% (6 aa)

CARCSAGTYQAQAGQSDCQTC
| .| .|.|. . .   |..|
CIPCPEGEYSNTTDSYTCTPC

TNFR_c6 23193.AA TNFR_c6 836-854 28 1.879706 4.98 Pfam 1-20 (41) Show / Hide
Range on Protein: 836-854
Range on HMM: 1-20/41
Sequence Identity: 28% (6 aa)

CSAG-TYQAQAGQ-SDCQTCQ
|. | ||..  .. . |. |.
CPPGKTYTD-WNHVPHCLSCT

GCC2_GCC3 23193.AA GCC2_GCC3 738-755 44 3.545678 3.54 Pfam 16-33 (49) Show / Hide
Range on Protein: 738-755
Range on HMM: 16-33/49
Sequence Identity: 44% (8 aa)

HGAYQDQTGQTSCDGCGV
.| ||.. ||.||  |..
RGTYQNEEGQDSCIPCPP

HYR 23193.AA HYR 1029-1051 41 0.025881 9.64 Pfam 1-24 (86) Show / Hide
Range on Protein: 1029-1051
Range on HMM: 1-24/86
Sequence Identity: 41% (10 aa)

VDTTPPVI-SLTQGVNVTVEAGST
||||||.. . . ..  ||| |..
VDTTPPTVENCPNNIFRTVELGTS

HYR 23193.AA HYR 1089-1100 50 3.814148 2.5 Pfam 64-75 (86) Show / Hide
Range on Protein: 1089-1100
Range on HMM: 64-75/86
Sequence Identity: 50% (6 aa)

TVDYMATDRSGN
|| | ..|..||
TVTYTFQDNAGN

HYR 23193.AA HYR 1173-1196 40 0.346527 5.93 Pfam 62-86 (86) Show / Hide
Range on Protein: 1173-1196
Range on HMM: 62-86/86
Sequence Identity: 40% (10 aa)

DYSIVYTARDDVGNTA-HATRTLTV
.... ||..|  ||.|   | | ||
QTTVTYTFQDNAGNQADTCTFTVTV

HYR 23193.AA HYR 1370-1390 36 7.620799 1.51 Pfam 58-79 (86) Show / Hide
Range on Protein: 1370-1390
Range on HMM: 58-79/86
Sequence Identity: 36% (8 aa)

PAGSTYTVDFIVTDAAGNSD-S
| | ..||  ...|.|||.. .
PVGEQTTVTYTFQDNAGNQADT

HYR 23193.AA HYR 1498-1525 41 6.398754 1.76 Pfam 58-86 (86) Show / Hide
Range on Protein: 1498-1525
Range on HMM: 58-86/86
Sequence Identity: 41% (12 aa)

PVGTLYVVNASVMDGAGNTA-TRTFRYLI
|||  ..| . . | |||.| | ||.  .
PVGEQTTVTYTFQDNAGNQADTCTFTVTV

HYR 23193.AA HYR 1526-1532 85 10.733995 1.02 Pfam 1-7 (86) Show / Hide
Range on Protein: 1526-1532
Range on HMM: 1-7/86
Sequence Identity: 85% (6 aa)

VDTTPPV
||||||.
VDTTPPT

HYR 23193.AA HYR 1581-1605 33 3.787572 2.51 Pfam 60-86 (86) Show / Hide
Range on Protein: 1581-1605
Range on HMM: 60-86/86
Sequence Identity: 33% (9 aa)

G-TYVVQYRTNDRYGNPA-EAARSVIV
| ...|.|   |. ||.| .    | |
GEQTTVTYTFQDNAGNQADTCTFTVTV

SH2 23193.AA SH2 2004-2034 34 0.002613 11.54 Pfam 18-52 (81) Show / Hide
Range on Protein: 2004-2034
Range on HMM: 18-52/81
Sequence Identity: 34% (12 aa)

ETLPVGSYILRYSDNTK-QLVLSVRSRS---RVQH
.. | |....| |..|. . .||||  .   ||.|
PGNPDGTFLVRESESTPGDYTLSVRDDGPGDRVKH

SH2 23193.AA SH2 2100-2136 42 1.2e-10 33.1 Pfam 1-40 (81) Show / Hide
Range on Protein: 2100-2136
Range on HMM: 1-40/81
Sequence Identity: 42% (17 aa)

YFHGQIDRSEAEKRLLA-NGSDNAFLVRARS--AGSYALS
..|| | |.|||..|..  . | .|||| ..   |.|.||
WYHGKISRQEAERLLMNPGNPDGTFLVRESESTPGDYTLS

SH2 23193.AA SH2 2098-2187 26 2e-09 38.53 SMART 1-87 (87) Show / Hide
Range on Protein: 2098-2187
Range on HMM: 1-87/87
Sequence Identity: 26% (25 aa)

EPYFHGQIDRSEAEKRLLAN-GSDNAFLVRA--RSAGSYALSILSLKSKDAKCHHHLLEVNEEGLVTLNNDLLSPPCTSIVGAVELLRRVPPE
.|..|| |.|.|||. |... . | .||||   ...|.|.||. .      |..| ... |..| . .  .  .... |.   |.  .. |  
QPWYHGNISREEAEQLLKNPGMPDGDFLVRDSESNPGDYVLSVRWK----GKVKHYRIRRNDDGKYYIDET-WRRKFPSL-ELVNHYQHNPLG